Digital Commons Network^™

Exploring A School Culture And Climate Where Students Can Flourish: Using Focus Group Methodology To Capture Key Stakeholder Perceptions About School Culture And Climate In An Alternative Education High School., Michael Lee Paynter

Dissertations

This study was a qualitative action research project that involved focus groups of key stakeholders at an alternative education high school including: students, teaching staff, classified staff, supervisors, families, and collaborative partners. A semi-structured interview guide was used to discover their perceptions of a school culture and climate where students FLOURISH. The word FLOURISH is used in this research to describe the optimal experience of thriving and growing as well as an acronym that contains the elements that a literature review found to be important for such environments serving the most vulnerable student populations. This type of research is especially …

Uncovering The Protological Hermeneutics Of George Mccready Price And Benjamin Warfield, Sergio L. Silva

Dissertations

Problem

The problem this dissertation addresses is the protological hermeneutical impasse between George McCready Price and Benjamin Warfield over whether biblical protology should be interpreted literally or symbolically in response to the evolutionary theory.

Method

To identify, compare, and contrast the protological hermeneutics of George McCready Price and Benjamin Warfield, this dissertation adopts an interdisciplinary methodology that seeks to integrate historical theology, systematic theology, and exegetical-biblical theology.

Conclusions

The protological hermeneutical impasse between George McCready Price and Benjamin Warfield over the interpretation of biblical protology was caused by how they applied their views on epistemology. On the hermeneutical level (where …

Primed To Lead: A Case Study Of Global Leader Education In South Korea, Landis Garrel Fryer

Dissertations

Drawing students from an international audience, some higher education institutions are educating global leaders through business school programs. This is an instrumental case study of one such program€”the Global Masters of Business Administration (Global MBA) at Korea University Business School. This dissertation analyzed interviews, onsite observations, and documents with the concepts of globalisms and cosmopolitanism as a framework. the findings uncovered programmatic features designed to educate global leaders and participant considerations of global leader characteristics. the conclusion situated these considerations and findings within existing leadership theory and placed the case as an example of shared cosmopolitanism and global leader education …

The Role Of Notch-1-Mediated Repression Of Pten On Growth And Cancer Stem Cell Survival In Trastuzumab Resistant, Her2+ Breast Cancer, Andrew Thomas Baker

Dissertations

Trastuzumab targets the ErbB2 (HER2) receptor on breast cancer cells to attenuate HER2 driven tumor formation. Trastuzumab reduces both downstream PI3K/Akt and MAPK pathway signaling as well as the breast cancer stem cell (BCSC) population. BCSCs are hypothesized to be responsible for tumor recurrence, metastasis, as well as drug resistance. Today, resistance to trastuzumab remains a major clinical problem for women diagnosed with HER2+ breast cancer. Attenuation of PI3K/Akt and MAPK pathways may occur through the tumor suppressor, PTEN. Women with HER2+ breast tumors expressing less PTEN and increased PI3K/Akt or MAPK activity have worse overall outcome. Previously we have …

We Can Do Better: Evaluating An Intervention Remedying Caseworkers’ Negative Racial Bias Towards African American Families Involved In Child Welfare, Adrianne Michele Fletcher

Dissertations

Given that U.S. history documents the severing of African-American family ties by isolating parents from each other and their children under slavery, it is imperative that the child welfare system be free of any echoes of that holocaust. Yet many scholars and practitioners who lament negative racial attitude, both implicit and explicit, may continue to contribute to the over-representation of African-American children in the U.S. child welfare system. This study proposes to examine a subcategory of practitioner attitudes, those about the caregivers’ race, and how those attitudes can be altered through a reflective educational experience. Drawing from pre-existing research about …

Research Practices Of Music Educators: A Review Of The Journal Of Research In Music Education, Clifton Brent Mcreynolds

Dissertations

Music Education researchers face the same challenge of producing valid, reliable, and thorough work as any field in education. A content analysis was conducted on the Journal of Research in Music Education from 2011-2016 to determine what research trends were occurring and whether or not those trends are continuations of existing literature. Investigation included distributions of research designs as well as the four components Crotty recommended for quality research. Findings supported previous research indicating more qualitative studies within the journal. Also, for those articles having three or four of Crotty’s components, qualitative coding of these components were categorized into constructive-where …

Investigating Novel Methods Of Interaction With Pharmaceutically Relevant Enzymes, Cory T. Reidl

Dissertations

Metalloproteins requiring one or more metal ions for normal function make up 30% of all known proteins, and many critical biological pathways contain at least one metallo-enzyme. Di-nuclear metallo-proteins constitute a large class of these proteins yet we currently lack effective methods of inhibiting these enzymes for the development of new medical therapies, particularly for the discovery of new antibiotics. Our work has focused on developing novel functionalities that selectively interact with di-nuclear catalytic centers, and we are targeting three separate di-zinc-metallo-enzymes that are unique to bacteria and play key roles in their growth and development. These enzymes are DapE, …

Aging Well In 21st Century America: Towards A Theological Ethics Of Aging, Chrisitan Cintron

Dissertations

As Third Agers transition into life after work they are faced with a renewed challenge, living the good life. The normative images emanating from the social and cultural landscape allow Third Agers to either envision and live their new life, or adopt a course set out for them. These new lives require a re-discovery and re-defining of the self, a reinterpretation of one's role in society, and relationship to others. As with other phases of life, individuals need guidance when confronted with images of living well that are contradictory or perhaps antithetical to what they imagined for themselves. Various social …

Mutual Regulation Of Crp And N(Epsilon)-Lysine Acetylation In Escherichia Coli, Robert James Davis

Dissertations

Post-translational modifications, such as N(epsilon)-lysine acetylation, are known to alter the behavior of transcriptional regulators in eukaryotes, but very little is known about the consequences of acetylation on transcriptional regulation in bacteria. Here, I provide evidence that a global transcriptional regulator of carbon metabolism, cAMP Receptor Protein (CRP), promotes both enzymatic and non-enzymatic lysine acetylation in E. coli. Non-enzymatic lysine acetylation occurs when cells ferment acetate, such as during growth on high concentrations of glucose. Intriguingly, CRP can be non-enzymatically acetylated on several lysines, including lysine 100 (K100). I provide evidence that neutralization of the K100 positive charge, as would …

Characterization Of Multi-Albumin Pegylated Complexes Synthesized Using "Click" Chemistry As Drug Delivery Systems, Jonathan Alejandro Hill

Dissertations

Due to its ability to transport hydrophobic materials through the bloodstream, human serum albumin has become an intriguing component for drug delivery systems. The most pressing concerns with current albumin-based systems are the risk of pathogenic transfer associated with human-sourced blood proteins, the negative effect on osmotic pressure due to administration of a large dose of albumins, the potential immune response and loss of biological activity due to heavy modification of these albumins, and the need for organic solvents for preparation of these products. Key residues in the two main drug binding sites, DS1 and DS2, are conserved in bovine …

Elevated Hydrostatic Pressure Selectively Enhances Matricellular Gene Expression In Human Trabecular Meshwork Cells, Jonathan Lautz

Dissertations

Primary open-angle glaucoma (POAG) is a progressive optic neuropathy

characterized by loss of peripheral vision secondarily associated with elevated intraocular pressure (IOP). Transforming growth factor (TGF)-β2 is markedly elevated in the aqueous humor (AH) of patients with POAG. It has been previously shown that TGF-β2 increases IOP, in part, by inducing expression and release of endothelin-1 (ET-1) and connective tissue growth factor (CTGF) within the trabecular meshwork (TM). ET-1 and CTGF may ultimately lead to increases in IOP by enhancing TM cell contractility and extracellular matrix (ECM) deposition. Here we confirm that TGF-β2 enhances mRNA content of ET-1, CTGF, and …

Investigating The Effects Of Student Engagement On Latina/O Community College Students, Manuel Salgado

Dissertations

As the growth of the largest ethnic minority group, Latina/os, continues to grow there is an increasing concern that the current educational system is not effectively meeting the academic needs of this group of students. The community college sector has gained greater recognition for its potential to meet the needs of a much broader scope of students, particularly low-income and students of color. This study aims to contribute to the understanding of the Latina/o experience and the factors that contribute to college success among community college students. Specifically, this study used hierarchical multiple regression and logistic regression analysis to investigate …

"Let's Get Together And Chew The Fat": Women, Size And Community In Modern America, Amelia Earhart Serafine

Dissertations

"Let's Get Together and Chew the FAT: Women, Size, and Community in Modern America" argues that between 1948 and the 1980s, women in America formed communities around issues of size in order to claim agency over their bodies. Primarily concerned with losing weight, many women in these groups nonetheless created new tools and abilities with which to resist oppression based on body size. Some women went as far as to form explicitly positive fat identities and reject compulsory slenderness. This dissertation investigates four cases studies: TOPS (Take off Pounds Sensibly), Overeaters Anonymous, Weight Watchers, and the Fat Liberation movement of …

Mild Hydrofunctionalizations Of Olefins Using More Cost-Effective Metal Catalysts, Alexander James Villani-Gale

Dissertations

The focus of this dissertation is the study of alkene hydroaylation reactions. In the first chapter, a review of the relevant literature concerning zinc- and iron-catalyzed hydroarylation of unsaturated bonds is presented. In chapter two, the development of a zinc-catalyzed hydroarylation of alkenes is presented, which is quickly followed by a detailed investigation into the probable mechanism. Chapter three discusses the development of an iron/silver-catalyzed arene prenylation reaction, followed by the development of an iron/zinc-catalyzed arene prenylation reaction. The final section of chapter three discusses the adaptation of the iron/zinc-catalyzed arene prenylation into an undergraduate organic teaching laboratory.

What Is The Relationship Between Vitamin D Status, Pregnancy Symptoms And Quality Of Life?, Jennifer Woo

Dissertations

Purpose and Background/Significance: The main purpose of the study is to determine: (1) to determine if there is a relationship between vitamin D status, pregnancy symptoms, health promoting behaviors, and quality of life and (2) to determine if differences exist in pregnancy symptoms, health promoting behaviors and quality of life between African American and Hispanic women. There is evidence to show that vitamin D deficiency has been associated with numerous symptoms such as musculoskeletal pain, poor sleep, and depression. However, whether low levels of vitamin D is associated with these and other symptoms during pregnancy is unknown. What is known …

The Lived Experience Of Intersectionality Among African American Women With Breast Cancer, Teri D. Armour Burton

Dissertations

African American women (AAW) continue to have breast cancer mortality rates that are 42% higher than White women (De Santis et al., 2015). Researchers suggest that an epistemological approach that integrates the biomedical and feminist models would be more effective in addressing health disparities. The concept of intersectionality, which grew out of the Black feminist movement, provides a lens in which to view the lived experiences of AAW with breast cancer. The intersectionality paradigm attempts to address the marginalized, oppressive, intersecting social existence of AAW through the examination of identity, social class, and power.

This qualitative study applied a descriptive …

Faith And Homelessness: Examining The Influence Of The Faith-Based Component Of A Transitional Housing Program On The Attitudes And Behaviors Of Homeless Men, Douglas Edward Luffborough Iii

Dissertations

Homelessness is a social and public policy concern. In the United States, homelessness is a problem with multiple and complex causes that include mental illness and the effects of physical, economic, and social conditions such as extreme poverty, exposure to the elements, mental and substance abuse disorders, malnutrition, and victimization. Transitional housing is a temporary option offered as a response to homelessness, recognizing that if individuals are provided with shelter, they may be supported in their attempt to achieve self-sufficiency.

There is some evidence that supports the benefits of federally funded transitional housing programs, but to date, few studies have …

Examining Hybrid-Gift Philanthropy In Division I Intercollegiate Athletics: A Mixed Methods Study, John Thomas O'Sullivan

Dissertations

Over the past few decades, the money and attention associated with Intercollegiate Athletics (ICA) has exploded. At the same time, however, many ICA departments claim to be at a financial crossroads with coaching salaries and operational costs soaring upwards. Not surprisingly, ICA departments are responding by focusing on increasing their fundraising in innovative ways. Perhaps the most interesting of these is in the area of hybrid—or blended—giving, which combines cash with a deferred gift. While these gifts have the potential to help generate substantially more revenue for ICA, unfortunately there is limited empirical research surrounding them.

In an effort to …

Examination Of The Collaboration Between Career Technical Education And Core Teachers In Linked Learning Pathways, Lucia M. Van Scyoc

Dissertations

Purpose. The purpose of this mixed methods study was to determine how teachers in Linked Learning Pathways rate the effectiveness and identify the impact of the collaboration strategies of a shared purpose, interdependent team and focus on results as they are used in the integration of career and technical education and core academic courses. This also included identifying and describing the criteria used by teachers to determine positive impact in identifying positive collaboration strategies.

Methodology. A mixed method research design, consisting of quantitative and qualitative data, was used to conduct this study. Specifically, an explanatory sequential design model starting with …

Disrupting Poverty: The Impact Of Academic Optimism And Organizational Citizenship Behaviors On Student Achievement In California High-Poverty Secondary Charter Schools, Derek King

Dissertations

ABSTRACT

Disrupting Poverty: The Impact of Academic Optimism and Organizational Citizenship Behaviors on Student Achievement in California High-Poverty Secondary Charter Schools

by Derek King

One of the byproducts of the Civil Rights Act of 1964 was the commissioning of a study by the United States Department of Health, Education and Welfare to better understand the disposition of the nation’s educational system. By 1966, the most comprehensive educational study to date was completed, the Equality of Educational Opportunity (Coleman et al., 1966). The findings shocked the nation by concluding that familial poverty restricted a student’s academic achievement, rendering all school-based interventions …

Spectroscopic And Spectro-Astrometric Analysis Of T Tauri Stars, Logan Ryan Brown

Dissertations

To understand our own solar origins, we must investigate the composition of the protoplanetary disk from which the solar system formed. To infer this, we study analogs to the early solar system called T Tauri stars. These objects are low-mass, pre-main sequence stars surrounded by circumstellar disks of material from which planets are believed to form. We present high-resolution, near-infrared spectroscopic data for the T Tauri stars DR Tau and AA Tau using NIRSPEC at the Keck II telescope. For DR Tau, a spectro-astrometric analysis was performed, obtaining sub-seeing spatial information on water emission. Alongside a disk model, we constrained …

The Synthesis And Characterization Of Photoluminescent Conjugated Frameworks Containing Silicon And Germanium, Douglas William Hammerstroem

Dissertations

Siloles and 9-heterofluorenes (Si, Ge) are conjugated π-electron systems containing Group 14 atoms which demonstrate unique properties such as high electron affinity, mobility, and bathochromically shifted optical spectra relative to their all-carbon analogs. This is due to their low-lying lowest-unoccupied molecular orbital (LUMO) which is resultant of the σ*-π* conjugation between the exocyclic groups at the Group 14 center and the butadiene unit of the ring. As a consequence, they have received considerable attention for their use as components for a wide variety of optical and electronic applications such as organic light emitting diodes (OLEDs), photovoltaic devices, field-effect transistors (FETs), …

Identifying The Complexity Of Bipolar Disorder, Brandie Marie Stiles

Dissertations

Bipolar disorder is a complex illness that is difficult to correctly diagnosis and treat. Experts estimate that a correct diagnosis and treatment for bipolar disorder may be delayed for up to 7-10 years after symptoms become problematic. The primary purpose of this study was to identify the complexity of diagnosing bipolar disorder, including diagnostic patterns, recommended treatment, and patient response. A focused ethnography, including in-depth interviews and a retrospective chart review, were completed to answer the research questions: 1) What is the nature of the experience of receiving a diagnosis of bipolar disorder? 2) What are the diagnostic and treatment …

Bullying Experiences And Resilience In Lgbtq Youth, Melinda Mccormick

Dissertations

Many young LGBTQ people are experiencing bullying which can lead to increased risk of suicide, drug abuse, and depression, as well as an increased risk of out-of-home placements in either foster care or homeless shelters. As a result of this, LGBTQ young adults are often framed as being at risk. Although this has been helpful in the past in order to raise awareness of the challenges experienced by LGBTQ young people, there is also evidence that they show resilience in response to those challenges. In order to advance the social work value of being strengths-based, this research looked for examples …

Supporting Students With Disabilities Entering The Science, Technology, Engineering, And Mathematics Field Disciplines, Karen Marie Dishauzi

Dissertations

Extensive research exists on female, African American, and Hispanic students pursuing Science, Technology, Engineering and Mathematics (STEM) field disciplines. However, little research evaluates students with disabilities and career decision-making relating to STEM field disciplines. This study explored the career decision-making experiences and self-efficacy for students with disabilities. The purpose of this research study was to document experiences and perceptions of students with disabilities who pursue, and may consider pursuing, careers in the STEM field disciplines by exploring the career decision-making self-efficacy of students with disabilities. This study documented the level of influence that the students with disabilities had or may …

Anthropogenic Disturbance Modulates Mammal Community Diversity, Assembly, & Abundance: Emerging Infectious Disease Risk In The Greater Yellowstone Ecosystem, Leticia Andrea Gutiérrez Jiménez

Dissertations

This dissertation examines the role of mammalian biodiversity in maintaining overall ecosystem health in the Greater Yellowstone Ecosystem (GYE). The study explores the pathways by which anthropogenic disturbance prevents or promotes the emergence of human infectious diseases. I studied two paramount research questions: Question 1: What are the direct effects of anthropogenic disturbance on rodent community assemblages and the consequent indirect effects on public health? I first surveyed the GYE rodent community and their pathogens by using land use as a measure of anthropogenic disturbance (e.g., human settlements, horseback ranches, pastures, undisturbed). I identified pathogens in rodent blood samples by …

Synthetic Ion Channels: A New Class Of Membrane Disruptor And Efflux Pump Inhibitor For The Recovery Of Antibiotic Potency, Mohit Bharatkumar Patel

Dissertations

Antibiotic resistance has become a world-wide health care crisis. In 2013 there were 50,000 deaths in U.S. and EU, associated with hospital acquired bacterial infections. This problem is exacerbated by the lack of new antibiotics in development. Here, we report that synthetic amphiphiles represent a new class of adjuvants that rescue antibiotic potency against multidrug resistant bacteria. Hydraphiles are amphiphiles, designed and synthesized in Gokel lab, that show many of the same properties as protein ion channels. Hydraphiles were previously shown to have antimicrobial activity against Escherichia coli, Bacillus subtilis and Saccharomyces cerevisiae. Here, we report that hydraphiles recover the …

Endogenous Small Interfering Rna: Insights Into Esirna Biogenesis And Their Precursors, Andrew White Harrington

Dissertations

Rarely in research is the path to an answer straightforward. Initial questions lead to more questions, many times doubling back to allow for greater insight into the original question. For example, discovery of interactions between previously unrelated pathways can lead to breakthroughs with regard to understanding of gene regulation. One such novel interaction and the subsequent discoveries this interaction spurred are discussed herein. Transposons, or “Jumping Genes” are mobile genetic elements found throughout all three major domains of life. Transposons comprise 44% of the human genome and possess the ability to move within the genome. This ability makes them an …

Color-Mediated Foraging By Pollinators: A Comparative Study Of Two Passionflower Butterflies At Lantana Camara, Gyanpriya Maharaj

Dissertations

Colorful floral signaling and resulting insect foraging behaviors have only been extensively examined in hymenopteran pollinators, especially bees, in comparison to flies, beetles, and butterflies regardless of their ecological importance. Therefore, my study provides novel information by focusing on foraging behaviors of adult passionflower butterflies, Heliconius melpomene and Dryas iulia, to the color changing flowers of Lantana camara. My dissertation which is divided into four chapters, aims to explore various aspects of color mediate foraging in passionflower butterflies by combining observations in the wild with controlled field and laboratory experiments. In the first chapter I reviewed flower color development and …

Sexual Orientation Microaggressions In High Schools, Marti Lee Baricevic

Dissertations

Sexual orientation-based discrimination in schools has evolved from primarily blatant, overt forms to include subtler and ambiguous forms. Recent research has found that same-gender-attracted youth are more resilient in managing school-based discrimination than previously reported. Within the framework of Symbolic Interactionism, this dissertation used a basic qualitative approach, influenced by Grounded Theory methods, to investigate sexual orientation microaggressions in high schools, strategies employed by same-gender-attracted students in managing sexual orientation microaggressions, and the relationship between microaggressive experiences and sexual identity. Fourteen adolescents, ranging from ages 16 to 19, from seven separate schools, who self-identified as lesbian, gay, bisexual, and queer, …