Digital Commons Network^™

Unraveling The Antiviral Mechanisms Of Bat Cells: Processing Of Genomic Rnas By Dicer In Bat Cells Limits Sars-Cov-2 Replication, Iyanuoluwani Owolabi

Dissertations

Bats are reservoirs for numerous viruses that cause serious diseases in other animals and humans. Several mechanisms are proposed to contribute to the tolerance of bats to these pathogens. This study investigates the response of bat cells to double-stranded RNA generated by SARS-CoV-2 replication. Here, we found the involvement of Dicer in the processing of viral genomic RNAs during SARS-CoV-2 infection. Examining RNA sequencing of infected cells, small-interfering RNA (siRNA)-like fragments were found derived from viral RNAs. Depletion of Dicer showed a reduction in these RNAs and an increase in viral loads suggesting unlike other mammals, bats may use Dicer …

The Effect Of Implementing A Development Program Using Mental Imagery On The Time To Master Psychomotor Skills, Randal Agee

Dissertations

Psychomotor skills development programs that use mental imagery have been demonstrated to help individuals acquire psychomotor skills (Anu et al., 2020; Seymore-Walsh et al., 2020; Toth et al., 2020). The commercial trucking industry is presently experiencing a global shortage of qualified truck drivers (American Trucking Association, 2019; Staats et al., 2017). One reason individuals are avoiding or leaving careers as commercial truck drivers is the time spent away from home (Staats et al., 2017). A couple logistical strategies have been developed to improve the situation (Mittal et al., 2018; Prime Inc, 2024); however, for the solutions to be sustainable, the …

Resiliency Training For Music Therapy Students During Fieldwork Experiences, Crystal Weaver

Dissertations

All music therapy undergraduate and equivalency students in the United States must complete 1,200 hours of fieldwork experience to obtain degree conferment from an accredited and approved higher education program (American Music Therapy Association, 2023b, p. 1). While engaging in fieldwork had several benefits for music therapy students, such as the opportunity to build practical experience and refine skills, the experience also involved several challenges (Forinash, 2019; Tien & Trang, 2020). A challenge not yet thoroughly examined by faculty and staff within higher education music therapy programs was student mental health. To date, researchers had not examined the prevalence of …

The Barriers Preventing Generational Diversity In The Workplace: A Design-Based Research Study On Generational Diversity In The Workplace, Bryan T. Benke

Dissertations

Generational diversity poses numerous challenges within organizations, primarily as workplaces can now encompass up to five generations (BasuMallick, 2020). The scholar-practitioner explored various facets of generational diversity, highlighting barriers that impact the work environment, employee behavior, communication, knowledge transfer, technology adoption, management decisions, employer obligations, and cultural disparities. Despite increasing recognition of diversity, equity, and inclusion (DEI), entrenched biases persist, perpetuating stereotypes and marginalizing different generational cohorts (Fasbender & Gerpott, 2022; Gates, 2023; Renstrom, 2020; St. Aubin, 2019). Research revealed deficiencies in emotional intelligence (EI) among apprentices, particularly in self-awareness, self-management, social awareness, and relationship management, alongside challenges in achieving …

A Mixed Methods Study On Teacher Knowledge And Its Influence On Reducing Math Anxiety In Students, Shannon E. Cruz

Dissertations

Math anxiety has been a cause for concern in many people's lives before research commenced on its impact on math performance and learning. The dissertation in practice was focused on how a teacher’s lack of preparation and tools to support students with math anxiety could be changed in the field of education. Using a design thinking-based process, the student researcher identified a research question about how professional development about math anxiety helps teachers understand and support affected students while analyzing two null hypotheses regarding teacher understanding and ability to support students. Once the knowledge gap was identified, the student researcher …

Structural And Functional Characterization Of The Sos Pathway Genes (Sos1, Sos2, And Sos3) In Avicennia Marina: Insights Into Salinity Stress Tolerance, Mariam Obaid Alzaabi

Dissertations

Abiotic stress is a major challenge for agricultural productivity. Salinity stress is a vital environmental constraint that significantly limits plant growth and reduces crop yield worldwide. Halophytes, such as Avicennia marina, offer unique opportunities to dissect adaptive mechanisms underlying salt tolerance. This study focuses on the structural and functional characterization of the Salt Overly Sensitive (SOS) pathway genes (SOS1, SOS2, and SOS3) from A. marina. Full-length cDNAs of AmSOS1, AmSOS2, and AmSOS3 were cloned and characterized. The sequence analysis of these genes compared to the respective orthologs revealed high similarities and conservation of all …

Useful Measures Of Adult Attachment And Object Relations In Psychotherapy, Matilde A. Torallas Huerta

Dissertations

This is a literature review of objective and projective measures of attachment and object relations in adults, with the objective of reviewing outstanding research to identify the key factors for adult attachment assessment considered within attachment and object relations theories, what measures of adult attachment styles and dysfunction work best, and to provide key themes of assistance in the measurement of attachment and object relations in adult clients in psychotherapy. Theoretical foundations of attachment and object relations theory are reviewed as well as objective and projective instruments grouped by format. The 10 themes found to be useful in the assessment …

Shades Of Families: Exploring Intersectionalities Of Cross-Cultural Parenting Experiences In The U.S., Shu-Han Huang

Dissertations

As multiracial and multicultural families continue to grow across the United States, parents must navigate evolving cultural identities, systemic inequities, and increasing social and emotional pressures. These realities underscore the need for parenting resources that are both culturally responsive and emotionally supportive. This transcendental phenomenological study explored the lived experiences of 11 cross-cultural parents raising children in the U.S., with a focus on how intersecting identities and systemic forces shape parenting practices.

Guided by Critical Multiracial Theory and Intersectionality Theory, this study investigated parenting at the personal, familial, societal, and structural levels. Data were collected through semi-structured interviews and analyzed …

Temporal Dynamics In Spatial Random Field Theory: A Methodological Advance In Fmri Data Analysis, Theophilus Barnabas Kobina Acquah

Dissertations

Functional magnetic resonance imaging (fMRI) is a noninvasive tool for studying neural correlates of cognition by measuring task-evoked brain activity. Accurate interpretation of fMRI data depends on modeling the hemodynamic response (HR), which varies across brain regions and conditions. Brain plasticity adds complexity as functional changes during development and aging affect cognition, emotion, and behavior. BOLD signals display complex temporal dynamics influenced by both neural and physiological factors, challenging conventional models. This highlights the need for adaptive frameworks that account for temporal dependencies and spatial heterogeneity in neural activity detection. This current study enhances fMRI data analysis by integrating temporal …

Evaluating The Indirect Effect Of Microaffirmations On Intersecting Marginalized Identities And School Sense Of Belonging Among School Psychology Graduate Students, April Pratt

Dissertations

There is a discrepancy between the proportion of school psychologists identified as racially, ethnically, or linguistically diverse (REL) in the United States and the proportion of REL students they serve (Blake et al., 2016; Proctor & Owens, 2019). Current data estimates over 80% of school psychologists identify as white (Goforth et al., 2021), whereas more than 50% of U.S. public school students have non-white racial/ethnic identities (Irwin et al., 2024). In addition to increased recruitment of REL students to school psychology graduate programs, trainers in these programs must implement effective strategies to ensure retention. One method is to increase students’ …

A New Approach: Supporting Traditional Jazz Pedagogy Through Neuroscience, Christopher John Navarrete

Dissertations

Jazz musicians face a considerable learning curve in their performance endeavors. Numerous factors must be taken into account, including performance anxiety, memorization, active listening, ear training, mastery of musical techniques, and improvisation. Through the effective preparation of these skills, musicians tend to achieve success; however, this success fundamentally relies on the practice habits of the jazz musician.

A common approach in jazz pedagogy emphasizes the development of musical techniques such as scales and chords, modulating across various harmonic progressions. I will define this as a “traditional approach” used in jazz pedagogy. This method has been widely embraced by jazz musicians …

Examining The Effects Of Aryl Hydrocarbon Receptor Activation On Gut Immune Responses, Aspen Elizabeth King

Dissertations

Previous studies conducted in our laboratory suggest that activation of the aryl hydrocarbon receptor (AhR) activation with the prototypical ligand 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) initially suppresses both fecal and serum antigen-specific IgA responses, but fecal antigen-specific IgA levels recover from suppression while serum IgA levels do not. The purpose of the research detailed in this dissertation was to explore two potential mechanisms allowing for the more rapid recovery of antigen-specific IgA in the feces relative to the serum: (1) an increase in myeloid-derived suppressor cells (MDSCs) that enhance IgA antibody responses in intestinal tissues, and (2) an increase in the migration of …

Lived Experiences Of Reintegration For Afghanistan Veterans Who Were Army Combat Medics, Matthew Argento

Dissertations

The purpose of this study was to examine the lived experiences, strengths, and challenges of reintegrating into civilian life for GWOT Army veterans who were medics. Three veterans completed in-depth interviews about their reintegration experiences. Results were organized into domains, core ideas, and categories. This study added to the existing literature on both combat medics and military transitions and suggests new areas of future research on combat medics and their transitions post-military.

Participants expressed feeling nervous about their reintegration, primarily due to their familiarity with the structured military lifestyle, anxiety regarding how much or little their family would need them, …

Here Be Dragons: The Barriers Of Korean American Female Leaders In Secondary Schools, Joyce A. Kim

Dissertations

In K-12 public schools, there is a shortage of Korean American women in school leadership roles at the secondary level. This phenomenological study explores the contributing factors to this lack of representation, how institutions can recruit and retain Korean American female leaders, and how school systems can better support them. This study examines the leadership experiences of eight Korean American women. It utilizes the socio-political contexts of Korean patriarchy, the Model Minority Myth, and mentorship to help frame the problem of existing barriers. This study explores the following questions: What factors hinder Korean American women in school leadership? What structural …

Unlocking Potential: How Disengagement And Reengagement Shape Performance And Well-Being, Asha Bradley

Dissertations

Task persistence can become problematic when individuals continue to perform challenging tasks unlikely to yield success. Instead, it may lead to frustration, burnout, and negative psychological outcomes. Recognizing when to disengage from these goals is essential for reallocating resources toward more attainable objectives by shifting focus to a new task rather than persisting on the same one. Ultimately, this promotes emotional well-being and resilience. No previous studies have experimentally examined the combined processes of disengagement and reengagement. This study investigates the temporal and causal effects of disengagement and subsequent reengagement with an alternative task, making it the first to experimentally …

A Randomized Clinical Trial Exploring Two Doses Of Cannabidiol Daily For Eight Weeks On Health And Stress, Ryland Emery Townsend

Dissertations

This study’s purpose was to explore whether a 60 or 30 mg dose of cannabidiol (CBD) consumed in a beverage further supplemented with L-theanine, vitamin E, and vitamin C would alter various measures on subjective measures of stress, health and fitness related outcomes, and objective measures of stress. This double-blind, placebo-controlled clinical trial recruited healthy, college-aged subjects for randomization into one of four treatment groups where they consumed daily a single 12 ounce beverage for eight weeks containing 1) 60 mg CBD (CBD60) plus L-theanine; 2) 30 mg CBD (CBD30) plus L-theanine; 3) no CBD (CBD0), L-theanine alone, and 4) …

The Role Of A Web-Based Collaborative Cloud Application As A Tool For Spanish Acquisition: College Students’ Attitudes And Perceptions In Language Courses, Gloria Mercedes Monzon

Dissertations

The purpose of this study was to examine college students’ attitudes and perceptions toward using a web-based collaborative cloud application (Padlet) for aquiring the Spanish language. Conducted during the Fall 2024 semester, the study involved 53 college students from the Colorado Rocky Mountain region who engaged with Padlet in their Spanish language courses. A quantitative method was employed to address the following three research questions related to students’ perceptions of Padlet’s effectiveness in developing four essential skills: listening, speaking, reading, and writing; their attitudes toward Padlet’s features; and their overall evaluation of Padlet as a language-learning tool.

Q1 What are …

Sexual And/Or Gender Minority (Sgm) Stigma Within Nursing Schools: The Relationship Between Stigmatic School Attributes, Minority Stressors, And Sgm Nursing Student Mental Health, Michelle Gee

Dissertations

Nursing education is heteronormative and cis-normative, which has been correlated to stigma and ignorance exhibited by nurses towards sexual and/or gender minorities (SGM). Minority Stress Theory (MST) states that circumstances in the environment that promote stigma related to minority identities lead to unique minority stressors, such as discrimination. These minority stressors subsequently affect mental health. While it is known that SGM patients experience mental health issues that relate to stigma and discrimination in healthcare settings, nothing is known about SGM nursing students dealing with stigma and discrimination within nursing education. The aim of this descriptive correlational study was to inform …

Unschoolers In Higher Education: A Narrative Case Study Of Unschoolers’ Sense Of Belonging At University, Melissa Marie Carlson

Dissertations

Approximately 20% of families engaged in homeschooling have selected unschooling as their educational approach, with estimates suggesting this number may be even higher (Vesneski et al., 2022). Unschooling emphasizes the establishment of an environment where children can autonomously direct their learning by exploring their interests, unencumbered by traditional educational milestones or specific schedules (Arnall, 2018; Riley, 2020; Riley & Gray, 2015). Despite increasing public acceptance and recognition, research on the outcomes for unschoolers—particularly those pursuing higher education—is limited (Riley, 2020). The purpose of this study was to explore the importance of supporting unschoolers after they have matriculated, specifically fostering sense …

The Lived Experiences Of High School Students Serving As Peer Mentors, Heather S. Mitchell

Dissertations

Youth mentoring is an intervention that has demonstrated a tremendous amount of potential in mitigating a variety of struggles experienced by youth (DuBois & Rhodes, 2006; Grossman & Tierney, 1998; Herrera et al., 2008; “Impact Evaluation”, 2009; Karcher, 2009; Karcher, 2010; Kraus & Cleveland, 2016; Lerner et al., 2006; McQuillin et al., 2020). The exploration of the possible benefits to adolescents serving as mentors, especially nontraditional student mentors, has received little attention (Besnoy & McDaniel, 2016; Deane et al., 2018; James et al., 2014; Karcher, 2009; Karcher et al., 2010; Larson et al., 2020; Opara et al., 2023; Quimby et …

Longitudinal Assessment Of Blast-Related Traumatic Brain Injury (Tbi): Impact On Structural Neuroimaging Correlates, Working Memory, And Processing Speed, Carmen Velez

Dissertations

The conflicts in Afghanistan and Iraq led to a significant surge in blast-related traumatic brain injuries (bTBIs). However, our understanding of their lasting neurological impacts remains incomplete. To our knowledge, this is the first longitudinal study of its size to explore whether increasing levels of blast exposure predict neural atrophy or cognitive decline over time. We analyzed 149 baseline and follow-up data sets from service members categorized by blast exposure: blast naïve (n = 57), single blast (n = 70), and multiple blasts (n = 22). Participants underwent structural magnetic resonance imaging (MRI) and neuropsychological assessment.

All data were drawn …

Balancergnn: Balancer Graph Neural Network For Imbalanced Datasets, Mallika Boyapati

Dissertations

Addressing imbalanced datasets is challenging due to machine learning models' inclination to learn the majority class. Graph construction plays a major role in determining how Graph Neural Networks (GNNs) perform on imbalanced datasets. In this research, we introduce the BalancerGNN framework to tackle highly imbalanced datasets, demonstrating its effectiveness in fraud detection as one of the case studies. This framework is designed to work for any binary node classification dataset with significant class imbalances. This research addresses the following questions: i) How effective are feature engineering techniques in the case of imbalanced datasets? ii) How do graph representation learning and …

Quadratic Stochastic Processes: Algebraic Structures And Their Applications, Taimun Saleh Qaisar

Dissertations

This research focuses on the algebraic structures of the Quadratic Stochastic Processes (𝑄𝑆𝑃𝑠). In this work, we first study 𝜉𝑎- Quadratic Stochastic Operators (𝑄𝑆𝑂𝑠) linked to the partition P3. We simultaneously discuss the dynamics of the obtained 𝑄𝑆𝑂𝑠. Moreover, algebraic structure of the associated genetic algebra is studied. Further, we build Quadratic Stochastic Processes (𝑄𝑆𝑃𝑠) using the given Markov processes. Consequently, we obtain an ordinary differential equation for the resultant Quadratic Stochastic Processes (𝑄𝑆𝑃𝑠). Besides, we apply the solution of this ordinary differential equation for the option pricing problem. Thereafter, we construct Quadratic Stochastic Processes (𝑄𝑆𝑃𝑠) in three-dimensional space by …

Exploring Date Pomace As A Functional Ingredient In Bread: Nutritional And Functional Properties, Alaa Almoumen

Dissertations

This study investigated the incorporation of desugared date fruit pomace into wheat bread rolls and evaluated its effects on dough handling, bread quality, staling behavior, sensory acceptability, and nutritional composition. The research was conducted in three experimental phases: (i) development and characterization of a high-fiber dietary ingredient (HFDI) from date pomace, including its physicochemical and functional properties; (ii) bread fortification and quality assessment, where wheat flour was partially replaced with 0–20% HFDI to evaluate its effects on dough rheology, bread texture, color, moisture retention, shelf life, and consumer acceptance; and (iii) nutritional and physiological evaluation of the fortified breads, including …

Therapeutic Role Of Bioactive Peptides Derived From Hemoglobin, Priya Antony Pereppadan

Dissertations

Bioactive peptides are peptide fragments derived from the proteolytic cleavage or maturation of functional proteins that have shown promising therapeutic potential in addressing major health challenges, including type 2 diabetes, hypertension, and pain management. Diabetes is characterized by high blood glucose levels due to insufficient insulin production or utilization. There are several therapeutic targets for managing diabetes, and one key target is dipeptidyl peptidase IV (DPP IV) due to its role in glucose metabolism. In hypertension, angiotensin-converting enzyme 1 (ACE1) is critical for regulating blood pressure by forming angiotensin II, and its inhibition represents an established treatment strategy. Additionally, the …

The Cellular Trafficking And Targeting Of Angiotensin-Converting-Enzyme-2 (Ace2) And Neutral-Amino-Acid-Transporter (B0at1) Variants: Implications For The Pathogenesis Of Associated Diseases And Therapy, Nesreen Fayyad Alkhofash

Dissertations

Angiotensin-converting enzyme 2 (ACE2) and the neutral amino acid transporter B0AT1, encoded by SLC6A19, are membrane proteins with pivotal roles in human physiology. ACE2 is involved in regulating blood pressure and serves as the cellular entry receptor for SARS-CoV-2, while B0AT1 facilitates amino acid absorption in the intestine. The interplay between ACE2 and B0AT1, particularly their physical interaction and co-expression in the intestine, underscores their relevance in both normal physiology and disease. Dysregulation of these proteins has been implicated in conditions such as hypertension, and Hartnup disease and they have been usurped by SARS-CoV-2 to cause COVID-19. Despite their …

From Microplastic Impact To Biodegradation Solutions: Investigating Microplastic Pollution, Microbial Responses, And Efficacy Of Synthetic Microbial Consortia In Plastic Degradation, Rener Sahot De Jesus

Dissertations

Plastics, including microplastics, pose significant environmental threats due to their widespread presence and harmful ecological effects. This dissertation present three distinct, yet interconnected studies. First, a study on microplastic contamination in urban recreational parks was conducted in Al Ain, United Arab Emirates. Results showed that low-density microplastics were present in 87% of soil samples, with spectroscopic analysis identifying synthetic polymers such as polyethylene and polypropylene. Additionally, these microplastics were found to negatively affect soil pH and moisture levels, emphasizing the need for enhanced monitoring and management strategies. Second, the effects of ground microplastics on Photobacterium leiognathi strains, a marine luminous …

Resilient Learning For Anomaly Detection In Smart Living Systems, Sahar Abedzadeh

Dissertations

Cyber-Physical Systems (CPS) rely on anomaly-based detection methods to ensure the integrity and security of critical infrastructures such as smart grids, smart water metering systems, and advanced metering infrastructures (AMI). Anomaly detection methods are commonly used to identify deviations from normal system behavior by establishing learned profiles and thresholdbased distinctions between benign and anomalous events. However, conventional frameworks often fail to account for adversarial data poisoning attacks, unlabeled unsafe events, and environmental noise—factors that distort training data, degrade detection accuracy, and increase false alarms. This dissertation proposes a resilient learning framework that mitigates these biases by integrating quantile regression, M-estimation …

Nonparametric Finite Mixture Of Ising Graphical Models, Manal Hamadi Alloqmani

Dissertations

Statistical applications in fields such as bioinformatics, genomics, speech processing, image processing, and communications often involve large-scale models in which thousands or millions of random variables are linked in complex ways. Graphical models provide a general methodology for approaching these problems, and indeed many of the models developed by researchers in these applied fields are instances of the general graphical model formalism. This formalism gives a nice framework for capturing complex dependencies among the random variables and building a large-scale model for high-dimensional data. Recently, high-dimensional data are more assumed to come from one population and follow a parametric or …

Utilizing Drainage Induced Pfas Enrichment In Cascade Generated Foam For Efficient Removal At Wastewater Treatment Plants, Ethan Samuel Coffin

Dissertations

Observed trends in municipal solid waste landfills reveal a distinct disparity between per- and polyfluorinated alkyl substances (PFAS) composition entering in waste, mostly as diPAP and FTOH, and leaching out as FTCA and PFCA. These patterns are elucidated by compiling PFAS compositions in paper, textiles, and carpet, with known precursor transformations that generate FTCA and PFCA in leachate. Landfill leachate is commonly discharged to wastewater treatment plants (WWTP), which are ineffective at degrading PFAS and only serve as key conduits and discharge points for PFAS to the environment. Foam fractionation has been identified as a promising technology for concentrating and …