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The Effect Of Maternal Obesity On The Regulation Of Gene Expression And Cell Fate During Embryonic Cortical Neurogenesis, Thilina Thejinda Alawathugoda

Dissertations

Neurodevelopmental disorders have their roots in multifaceted origins that manifest during the earliest stages of embryonic growth, often linked to sophisticated gene regulation dynamics. A perturbed metabolic environment, specifically owing to maternal obesity, can lead to dyslipidemia, subsequently threatening the optimal development of the embryonic central nervous system. Growing evidence suggests that such metabolic irregularities during pregnancy can alter neurogenesis pathways, thus predisposing the developing fetus to neurodevelopmental disorders. One of the primary avenues through which these disruptions may occur is through alterations in histone modifications resulting from fluctuations in the expression of histone modifying enzymes or the availability of …

Synthesis Of Glucomannan-Xylan Composite Biofilms: Characterization And Applications For Food Packaging, Kholoud Al-Ajlouni

Dissertations

Scientists are most concerned about the need for green alternatives for efficient food packaging polymers to replace petroleum-based packaging products. The waste of corn cobs and the roots of the konjac plant contain hemicellulose, xylan and glucomannan respectively, and can be used to produce biofilms for food packaging.

The aim of these studies is to formulate biofilms from glucomannan-xylan blends that compete with petroleum-based plastic wrap. The biofilms must be strong, smooth, transparent, have a water vapor barrier, have the required mechanical properties and be cheap. Biofilms from glucomannan were stiff, lacked mechanical properties, and absorbed moisture. Therefore, it reacts …

Resiliency In Families Of Children With Low Vision, Deborah Lynn Mendoza

Dissertations

Resiliency is comprised of a complex interplay of risk and protective factors that change and develop over time. In the past, research focused on characteristics that allowed individuals to remain untouched by negative events around them; however, over time, this has morphed into investigating not only the characteristics individuals possess but those present within families as well. Families of children who have either a congenital or an acquired disability could face a unique set of risk factors over time that might require different protective factors to ensure they emerged from their adversity positively changed. As professionals, we have a responsibility …

A Study Of Policies And Responses To Chronically Absent Students In Illinois High Schools In The Four Southern Most Regions Of The Illinois Associaiton Of School Administrators, Charles Shain Crank

Dissertations

No abstract

Three Essays On International Migration And Remittances, Mir Tanzim Nur Angkur

Dissertations

This dissertation concerns the effects of international migration and remittances. The study explores two pressing issues: child marriages and livelihood strategies and how the receipts of remittances from abroad influence these outcomes. The research objectives and findings of each of the three essays is summarized below:

The first essay, titled “ Do remittances protect against child marriages? The Rohingyas in Bangladesh”, focuses on the role that remittances could play in combating this harmful practice among the displaced Rohingya population. Nearly one million Rohingya refugees have been living in one of the world’s largest refugee camp in Cox’s Bazar, Bangladesh. I …

Utilization Of The Endophytic Fungus Piriformospora Indica To Improve Salinity Stress Tolerance: An Insight Into The Date Palm’S Transcriptomic And Functional Genomic Approaches, Miloofer Sabeem

Dissertations

Sustainable agriculture in arid and semi-arid regions depends on managing soil salinity, which is a major environmental issue and a critical component of sustainable food production. Salinity has a significant impact on date palm growth and physiological functions. Plant growth promoting microbiota has become a viable option to improve plant growth and performance under salt stress. Piriformospora indica is a highly versatile root endophyte in agricultural fields capable of coping with salinity. Its role in increasing abiotic stress tolerance has been reported in several plant species, but not in date palms. This research study investigated the growth, biochemical and molecular …

The Relationship Between Startups’ Early Adoption Of Digital Platforms And Startups’ Pre-Money Valuation, Bader Hassan Faqeeh

Dissertations

The objective of this study was to explore whether there was a significant positive relationship between startups’ early adoption of the digital platforms, namely, 1) mobile application, 2) a premium domain name website, and 3) the existence of active startup social media accounts, and startups’ pre-money valuation. To achieve this objective, this research used a relatively novel method in entrepreneurial research to collect data, whereby LinkedIn’s Sales Navigator was used along with an automation tool in order to send hundreds of automated connection and message requests to investors on LinkedIn who were sent a copy of the survey questions along …

Biological Seawater Desalination Using Green Algae And Cyanobacteria, Abdul Mannan Zafar

Dissertations

Water shortage in many coastal parts of the world is reaching alarming situation, including the United Arab Emirates. Urbanization and rapid population growth are generating critical water demands with an increase in per capita consumption. Seawater is usually treated by membrane processes such as Reverse Osmosis (RO). However, this technology is energy intensive and generates excessive brine as a waste. The solution to this problem can be found in natural remediation techniques that can reduce salt concentration from seawater, such as halophytes. A salt-tolerant species can consume Na⁺ and Cl^- ions and increase cellular growth which is termed …

Characterization Of The Probiotic Properties Of Yeast Strains Isolated From Different Food Sources And Unraveling The Potential Nutritional Benefits Of Fermented Date Palm Pomace With Selected Probiotic Candidates: Untargeted Metabolomics And Carbohydrate Metabolites Of In Vitro Digested Fraction, Nadia Al Kalbani

Dissertations

The use of agricultural by-products, including date palm pomace (DPP), presents a promising opportunity for advancing sustainable food production. By fermenting DPP with novel probiotic yeast candidates, the bioactive properties of the by-product can be enhanced, potentially yielding health benefits. This dissertation aimed to (1) isolate yeast from fermented food products as well as to characterize their probiotic properties; (2) investigate the physiochemical properties of fermented DPP by selected yeast isolates; (3) evaluate the health benefits of non-fermented and fermented DPP samples both pre and post-digestion (bioaccessible portions); and (4) analyze the untargeted metabolites and carbohydrates metabolites in the bioaccessible …

Using Natural Language Processing To Evaluate Electronic Health Records Of Patients With Ovarian Cancer For Documentation Of Goals Of Care, Hillarie Elizabeth Joehl

Dissertations

Growing evidence supports the benefits of serious illness communication including goals of care (GOC) discussions and documentation in the electronic health record (EHR). Patients who discuss end-of-life (EOL) care with their clinicians are more likely to have positive outcomes including better-reported quality of life, less distress, and a higher likelihood of receiving care consistent with their preferences. Limited research suggests only a small fraction of ovarian cancer patients have such discussions with their clinicians. Using a novel natural language processing (NLP) methodology, this retrospective and descriptive study explores EHRs for patients with ovarian cancer to characterize documentation of GOC. Using …

Learning Science: Physical And Life Sciences In Curricula Across U.S. Schools Of Nursing, Valerie C. Sauda

Dissertations

Nursing educators are being challenged to provide curriculum that meets the changing healthcare environment and demand for creative, innovative nurses to assist in transforming healthcare into the future (Benner, Sutphen, Leonard, & Day, 2010; Institute Of Medicine, 2011). The liberal education provided within a baccalaureate of science in nursing (BSN) degree program provides a diversity of courses within the curriculum, including courses in the natural, physical, mathematical, and social sciences (American Association of Colleges of Nursing [AACN], 2008). Although nursing programs have included science courses in curriculum since the early 1900s (Nutting & Dock, 1907), there is lack of nursing …

It Is What It Is...Enduring The Never-Ending: The Lived Experiences Of Parenting Adult Children With Developmental/Intellectual Disabilities, Siri Gurunam Kaur Khalsa

Dissertations

The parental home is the predominant place of residence for adults with developmental disabilities/ intellectual disabilities (DD/ID) (Heller et al., 2007). More than 75% of the adult population with DD/ID, living in the US, continue to have their basic needs provided by parents (Williamson & Perkins, 2014). This is based on the estimated statistic of 1.0 to 1.58% of the entire U.S. adult population has a developmental disability (Anderson et al., 2019; Fox et al., 2015). About 2.9 million adults with DD/ID live with a parent 55 years (Byun et al, 2006), with more than 25% of these parents older …

The Lived Experience Of Older Nepalese Women With Urinary Incontinence, Somi Panday

Dissertations

Urinary incontinence (UI) poses a significant challenge for women across different cultures, as their diverse perceptions of UI impact their decision-making and choices, which are influenced by personal beliefs and preferences. Although research on women's experiences with urinary incontinence has shown substantial progress, encompassing various cultural contexts, more studies are still needed to examine cultural factors and employ the framework of transcultural nursing theory. Additionally, limited research has explored the experiences of older women with urinary incontinence in Nepal. This descriptive phenomenological study aims to explore the lived experience of older Nepalese women dealing with urinary incontinence. By applying the …

The Nursing Process And Allegations Of Malpractice Against Perinatal Registered Nurses In Florida, Genifer Jones Johnson

Dissertations

The nursing process as a foundation of professional nursing practice organizes care around the components of assessment, diagnosis, planning, implementation, and evaluation as required for professional registered nurses by the Florida Nurse Practice Act. Nurses who fail to comply with the Nurse Practice Act risk poor outcomes for their clients, disciplinary action from the State regulatory body, and legal action from the clients. This study was an examination of litigation claims against professional registered nurses in Florida who practice perinatal nursing seeking to identify and categorize allegations of negligence within the components of the nursing process. The expectation of this …

Stroke Survivors' And Informal Caregivers' Perceptions Of Depressive Symptoms After Stroke: A Mixed-Methods Sequential Explanatory Study, Tanya L. Breckenridge-Trotter

Dissertations

Poststroke depression (PSD) is a frequently occurring complication of stroke that affects up to 30% of all stroke survivors in the first 24 months after stroke. PSD has been correlated with increases in hospital length of stay and hospital costs, increased physical morbidity and mortality, the risk for recurrent stroke at one year, decreased functional outcome, decreased cognitive function, and decreased quality of life post stroke. Estimates are >50% stroke survivors with depressive symptoms are left untreated due to lack of recognition. Moreover, depression in family caregivers of stroke survivors may negatively influence stroke recovery and stroke survivor quality of …

Effect Of An Rn-Facilitated Post Discharge Phone Call Hf Self-Management Strategy, Vivia O. Haye

Dissertations

Heart Failure (HF) is associated with substantial financial challenges resulting in exorbitant yearly costs, and frequent readmits to the emergency department. Post-discharge HF self-management is crucial to improve client outcomes. The purpose of this quantitative, quasi-experimental, project was to examine whether the implementation of an RN-facilitated post-discharge phone call that focused on HF self-management strategies reduced return emergency department (ED) visits within 72 hours in an urban South Florida hospital. Orem's self-care theory and the Meleis transition model were used for their success in managing chronic illnesses such as HF. Both examined if an RN facilitated post-discharge telephone call that …

A Quantitative Study Of Perceived Fitness And Nutrition Levels Of Secondary Educators In Relation To Their Overall Job Satisfaction Program At A Private Midwestern University, Jessica Arico

Dissertations

The profession of education traditionally embodies an idea of educating children on math, science, social studies, and English along with other elective course areas. In recent decades, however, the burnout rates and mental health of educators have become a subject of media attention and the basis for many new professional development programs. The one element wholly ignored in this space is the physiological wellbeing of educators and the impact physical health has on mental health and job satisfaction. This study set out to provide a baseline for beginning the discussion and future research on the physiological impact on educators and …

Differences In Internalized Weight Stigma And The Treatment Of Clients In Larger Bodies Among Mental Health And Medical Professionals, Alexis Dosal

Dissertations

Weight is a complex interaction of several factors, including genetics, environment, adverse childhood experiences, culture, physiology, and emotional circumstances (Hale, 2019). By solely considering the categories of food consumption and individual activity, the belief of personal responsibility and controllability is perpetuated, which may lead to intentional or unintentional harm within interpersonal interactions and throughout medical services (Nutter et al., 2020). Weight bias refers to “stereotypes, negative attitudes, and discriminatory behavior toward individuals with larger bodies” (Nutter et al., 2020). Weight bias can be displayed as discomfort around those in larger bodies, holding beliefs that fat people are lazy or unattractive, …

Trauma Mediating The Severity Of Depressive Symptoms In Veterans With Ptsd, Meghan Curtin

Dissertations

Trauma serves as a risk factor for developing both posttraumatic stress disorder (PTSD) and depression. The purpose of this study was to examine trauma type as a mediator in the relationship between gender and severity of depressive symptoms among veterans with PTSD. The literature shows trauma type plays a role in developing PTSD and depressive symptoms. The first hypothesis was that female veterans who met the diagnostic criteria for PTSD would report higher levels of depressive symptoms than their male counterparts. The second hypothesis was that this gender difference would be partly mediated by levels of interpersonal trauma experience. Self-report …

Impact Of Physical Inactivity On Glucose Metabolism And Skeletal Muscle Secretions In Healthy Trained Rats And Potential Counteracting Effect Of Exercise And Protocatechuic Acid, Hira Shakoor

Dissertations

Modern societies have significantly transformed people's lifestyles, leading to a substantial increase in physical inactivity, which concerns 23% of adults and 81% of adolescents worldwide. Physical inactivity is a major factor contributing to the emergence of chronic diseases, most prominently Type 2 Diabetes (T2D), which exhibits a high prevalence in many countries. T2D is characterized by elevated blood glucose levels due to cells’ responsiveness to insulin. The shift towards inactivity likely occurred more rapidly than the genome's capacity to adapt, resulting in the metabolic dysfunctions underlying the development of T2D. Skeletal muscle is crucial in the onset of these metabolic …

Supervisory Impact On Counselor-In-Training Wellness, Erin Brumfield Grima

Dissertations

Counselors being able to engage in self-care practices to establish and maintain their wellness is a well-documented need. The risks of neglecting self-care are also well documented, yet counselors struggle to engage in consistent self-care practices (Baker & Gabriel, 2021; Posluns & Gall, 2020). When demand for counselors is constant (Bureau of Labor Statistics, U.S. Department of Labor, 2020) an examination of how to impact counselor wellness through supervision discussion of self-care is needed. The purpose of the study was to examine supervision discussion of self-care, support of mastery of counselors-in-training’s emotions and any resulting impact on counselor wellness. Data …

Computational And Experimental Investigation Of Elemental Sulfur And Polysulfide, Jyoti Sharma

Dissertations

Petroleum processing results in the generation of significant quantities of elemental sulfur (S₈), leading to a surplus of sulfur worldwide. Despite its abundance and low cost, the use of sulfur in value-added organic compound synthesis is limited due to its unpredictable and misunderstood reactivity. This dissertation aims to address this issue by tackling it from two angles. Firstly, by utilizing Density Functional Theory (DFT) calculations, the reactivity of sulfur in the presence of nucleophiles is studied. This facilitates the identification of organic polysulfide intermediates that can be generated under different conditions, as well as the corresponding reactivity for …

‘The Food Of The Home’ An Exploration Of Place And Practice Of Ordinary Women In Dublin City 1950-2000 On Irish Cuisine, Roann Byrne

Dissertations

Before the rise of restaurants and the accessibility of dining out, the home was where food engagement took place. In the recent surge of Irish Michelin restaurants, and our growing reputation for food culture, one element has been overlooked. Long before the great chefs and level of fine dining we have now – the heart of Irish food culture lay in the home. In the ongoing debate of what Irish cuisine is, we haven’t thought to look inwards, to the routes of our food engagement. This thesis seeks to understand the places, practices and engagement of ordinary women and food …

Experiences And Perceptions Of Rural Postpartum Women With Substance Use Disorders Inclusive Of Opioids Regarding Their Care, Debra L. Kramlich

Dissertations

Perinatal opioid use and neonatal withdrawal continue to rise rapidly in the face of the growing epidemic of opioid addiction in the United States, with rural areas more severely impacted. Despite several decades of research and development of practice guidelines, maternal and neonatal outcomes have not improved substantially. This focused ethnography aimed to address that gap by exploring rural women's experiences and perceptions of care to inform development of efficacious, holistic models of care to improve outcomes for these women and their children. Participant observations, oral accounts and formal interviews, and artifact review (i.e., health records, any print and electronic …

Baccalaureate Nursing Student And Faculty Views Of Effective Teaching, Kelley Noll

Dissertations

This study aimed to determine baccalaureate nursing student and nursing faculty views of effective teaching. Using the Teacher Behavior Checklist (TBC), a psychometrically sound tool, participants were sent an email containing a link to an online survey (Keeley, Smith, & Buskist, 2006). Baccalaureate nursing students (n=353) and nursing faculty (n=26) were sent the email with a response rate of 25.2% (n=89) and 69.2% (n=18) respectively. Participants were asked to rank order the top 10 qualities and associated behaviors they perceived as effective to nursing education.

‘The Magic Of Flowers’: An Explorative Study Into The Ways Floral Decorations Influence The Experience Of Guests In A Food Setting, In Contemporary Ireland, Johanna Banaditsch

Dissertations

This research project explores the influence of floral decorations on the experience of a diner in a food setting in contemporary Ireland by examining what and how dining experiences are designed, where floral decorations are relevant in this context and how they specifically influence people in these settings.

The research was conducted using the philosophical worldview of interpretivism. In order to answer the five sub-research questions and thus achieve the research aim, the research draws on existing literature on hospitality experiences, literature on the influence of flowers and qualitative primary research conducted through semi-structured in-depth interviews with flower providers and …

Atrial Fibrillation Management In Hispanic Adults, Tania Borja

Dissertations

Background: Research has found atrial fibrillation (AF) to be the primary or a contributing cause of death on 183,321 death certificates, and an underlying cause of death for 26,535 Americans in 2019. Findings indicate an increased AF diagnosis in White people compared to racial and ethnic minorities, contrasting widespread findings of increased prevalence of cardiovascular disease and ischemic strokes in minorities. Significant disparities—by race and socioeconomic status in disease distribution and access to testing and lifesaving treatments—have been documented, specifically associated with social determinants of health (SDOH); i.e., the conditions in which people are born, grow, live, work, and age. …

Exploring The School Nurse's Knowledge, Experiences, And Role In Trauma-Informed Care: Implications For School Nurse Practice, Lesha H. Rouse

Dissertations

School nurses as the only health care professional in schools with the potential to be in daily contact with students are in a critical position to create awareness, influence action, and provide leadership in trauma-informed care (TIC). However, there is a lack of research regarding school nurse TIC knowledge, experiences, and role in school health practice. Research has asserted the pervasiveness of Adverse Childhood Experiences (ACEs) in society as well as, it's potential to cause deleterious life-long health, educational, social, and economic outcomes (Bethell et al., 2017; Felitti et al., 1998; Stevens, 2019). Exploring the school nurse's role in TIC …

The Relationships Between Parenting Stress, Growth, And Development In Infants With Congenital Heart Defects During The First Six Months Of Life, Danica F. Sumpter

Dissertations

The stress experienced by parents at the time of diagnosis and hospitalization for their infant's congenital heart defect (CHD) is well recognized by healthcare professionals. Increased parenting stress has been negatively correlated with development in low birthweight infants. The primary purpose of this study was to explore the parenting stress as experienced by parents of infants with CHD during their first six months of life. In addition, the relationship between parenting stress and the growth and development of infants with CHD was explored. Due to the transactional nature of mother-infant interaction, both directions of this relationship were examined, the factors …

Sensing The Rhizosphere: Microbial Transcriptome Responses To Root Exudates And Redox-Active Metabolites, Ankita Bhattacharyya

Dissertations

The term “rhizosphere” describes the dynamic interface between plant roots and soil influenced by root exudates. It is a hotspot of microbial activity, plant-microbe, and microbe-microbe interactions. Distinct variations in bacterial diversity are thought to be driven by plant root exudates. However, the molecular details of these processes still remain unclear.

I addressed this gap by focusing on two strains, Pseudomonas synxantha 2-79 and Burkholderia lata 383, representing diverse groups of Gammaproteobacteria comprised of species with environmental, agricultural, and medical significance. In the first part of this project, we used a combination of metabolomics and RNA-seq to characterize transcriptome responses …