Digital Commons Network^™

From Devout Follower Of Muhammad To Committed Disciple Of Jesus: Principles And Methods Of Transition Phase Discipleship Among Adventist Believers From A Muslim Background In Ethiopia, Temesgen Bulti Besha

Dissertations

Islam is the second most dominant religion in Ethiopia commanding about 34 percent of the over one hundred ten million population of the country. The Seventh-day Adventist Church has not been successful, until recently, to effectively reach this large and growing Muslim population. In the last decade and half, hundreds of Ethiopian Muslims are coming to faith in Christ through the ministry of the Church. However, church members, leaders, and disciplers lack adequate understanding of the transition phase discipleship during which the new believers from Muslim background (BMBs) go through considerable challenges such as persecution, lack of social and economic …

War-Displaced International Students: A Qualitative Study Of Factors Influencing The Integration Of Ukrainians At A Midwestern Healthcare College, Ivan Riapolov

Dissertations

Problem

The war in Ukraine has disrupted the country’s higher education system, displacing Ukrainian students and affecting their mental well-being. These students encounter numerous challenges while adapting to new academic and cultural environments abroad. Higher education professionals must recognize and address the unique experiences and needs of international students by region of origin to better serve these populations. This study aimed to explore the factors that influence the social and academic integration of Ukrainian international students into a new culture and to inform institutions of the best practices for creating supportive environments for international students.

Method

The qualitative study explored …

Religious Participation, Subjective Happiness, And Purpose In Life As Predictors Of Psychological Resilience Among College Students At A Faith-Based Institution In The United States, Elaine Powell Oliver

Dissertations

Problem

During the transition from adolescence to adulthood, also known as emerging adulthood, many college students experience psychological distress, such as anxiety, depression, stress, and loneliness (Arnett & Tanner, 2009; DeRosier et al., 2013). For some students, their psychological distress will impact how they perform academically and whether they will persist in their academic goals (Hartley, 2012; Robbins et al., 2018). Many students lack the resilience needed to survive and thrive amid the challenges of college life (Lane, 2020; McLafferty et al., 2022; Watkins et al., 2012). -- Resilience is considered an essential psychological characteristic to assist students in navigating …

Navigating Big Data In Cyber Archaeology: An Updated Four-Field Approach Applied To San Miceli, Jared Wilson

Dissertations

Problem

This dissertation examines the evolving role of digital technologies in archaeological research, focusing on the management and interpretation of extensive digital datasets generated by modern excavations. Drawing on six years of comprehensive fieldwork at San Miceli, Sicily, this study critically evaluates and updates the established four-field methodology proposed by Levy et al. (2012), encompassing acquisition, analysis, dissemination, and curation. While traditional archaeological documentation methods rely heavily on analog techniques, these approaches increasingly fall short due to the rapid expansion and complexity of digital data.

Method

To address this gap, the dissertation refines and expands the current methodological framework by …

Relationship Between Financial Literacy And Financial Behavior Among Seventh-Day Adventist Full-Time Pastors In The North American Division Of The Seventh-Day Adventist Church, Edwin G. Romero

Dissertations

Problem

This investigation intended to examine the relationship between the financial literacy components of full-time pastors and their financial behavior components. Many pastors struggle with their finances and often retire unprepared due to having inaccurate or incomplete knowledge of relevant financial information and planning strategies.

Method

This study adopted a quantitative, descriptive, and correlational approach to investigate the financial and demographic characteristics of pastors. The questionnaire completed by participants was the financial literacy questionnaire developed by Stella et al. (2020), which helped measure general financial literacy among full-time pastors, and the Financial Management Behavior Scale (FMBS) developed by Xiao (2008) …

The Concept Of Israel In The Old Testament And Its Divine Purpose: An Exegetical And Theological Analysis, Gregory Arutyunyan

Dissertations

The aim of this study is to undertake a fresh look into the concept of Israel in the Old Testament and its divine purpose in the context of the overarching theology of the Hebrew Bible. The working method used in this research is a theological and exegetical analysis of relevant Hebrew text along with incorporating historical and socio-archaeological background studies.

The conclusion that is reached is that Old Testament Israel was a cosmopolitan community of people connected through biological links, intermarriage relationships, and political alliances. In a spiritual sense, the term Israel served as a characterizing title granted to Jacob …

Evolution Of Bacteria: The Subsequent Relationships Between Different Species And Their Hosts, Helen Appleberry

Dissertations

To explore the relationship between two recently identified bacterial species (S. anginosus and S. urinae), three aims were designed. First, niche ranges were identified via two metagenome databases. Different niche ranges were identified between the two groups. S. urinae was more specific to the urogenital tract. S. anginosus appeared to be present across human anatomical niches. Secondly, specific genes to the S. urinae group were identified. This gives insight into the genomic and phenotypic differences previously identified. Thirdly, a temporal study was created to view S. urinae in female urine over 8 weeks. This showed stability in the urinary microbiome …

Analyzing The Population Structure Of The Rhizobia Associated With Astragalus Lentiginosus, Joshua Adam Melnick

Dissertations

Legumes are an incredibly diverse and agriculturally important family of plants. They have a special relationship with symbiotic bacteria known as rhizobia which fix nitrogen into ammonia within nodules on their roots. Astragalus is the largest plant genus on Earth, and the species Astragalus lentiginosus is extraordinarily diverse, consisting of approximately 40 varieties. However, the rhizobia of A. lentiginosus have never been studied. In this study, root nodules were extracted from 17 varieties of A. lentiginosus to obtain rhizobial strains and metagenomes. A. lentiginosus primarily associates with rhizobia from the genera Mesorhizobium and Allomesorhizobium. There was little evidence of horizontal …

Deciphering The Source Of Escherichia Coli In Urinary Tract Infections: A Comparative Metagenomic Analysis Of The Female Urogenital Microbiome, Alexis Annabel Avalos

Dissertations

In 2019, there was a 140.19% increase in deaths due to urinary tract infections (UTIs) compared to 1990, worldwide. One of the common uropathogens known to associate with UTIs in females is Escherichia coli. The prevailing belief is that E. coli in the bladder originates in the rectum, passing its way from the perineal, to the vagina, and finally into the bladder. Known as the Fecal-Perineal-Urethral (FPU) hypothesis, this “origin story” has been supported by several studies that have relied on genotyping or serotyping isolates collected from the bladder and rectum. Most notably, culturing isolates from samples has been central …

Reconceptualizing Christian Nationalism, Robert Stevenson

Dissertations

This thesis sets out to critically engage with existing research on Christian nationalism. It argues that current research suffers from a methodological focus that is too broad, and theoretical grounding that is too imprecise, both of which prevent researchers from grasping the full scope and intent of Christian nationalism, as imagined by Christian nationalists themselves. Drawing on data collected from X accounts (formerly Twitter) of Christian nationalist users, Christian nationalist podcasts, and Christian nationalist books, it employs qualitative content analysis, mapped to Bourdieusian field theory to provide a structured approach for the understanding complex data involving multiple spheres of power, …

Role Of Coronavirus Envelope Protein On Infectivity, Garrett E. Zaagman

Dissertations

Coronaviruses infect a wide range of hosts and have caused recent human pandemics. While much has been learned, gaps remain in understanding viral assembly and egress, particularly the role of the envelope (E) protein in specific infectivity. To study this, recombinant MHV viruses were created with E gene deletions and HiBiT-tagged spike (S) proteins to monitor virion release. In mouse cells, MHV∆E S-HiBiT secreted less spike and fewer infectious particles, indicating reduced specific infectivity. Comparisons between human HeLa-CEACAM and mouse DBT cells showed species-specific support for virus production. TMED10, a host membrane protein, was tested as a potential E-interacting partner …

Anti-Inflamatory Mechansim Of Bacillus Subtilis Derirved Exopolysaccharide, Adrian Taylor Ibarra

Dissertations

Exopolysaccharides (EPS) secreted by the commensal bacterium Bacillus subtilis exhibit potent anti-inflammatory properties, yet the underlying molecular mechanisms remain incompletely understood. We hypothesized that EPS reprograms antigen-presenting cells toward a tolerogenic state by modulating TLR4–MyD88 signaling. To test this, we began using a chemically defined, high-yield EPS production and purification protocol that largely eliminates protein and DNA contaminants, thus improving functional reproducibility across experiments using this new method. In vitro, EPS engaged TLR4 on murine dendritic cells (DC2.4) without inducing classical NF-κB activation, seen by LPS stimulation. Rather, EPS treatment upregulated inhibitory molecules, PD-L1 and PD-L2 while leaving activation markers, …

Investigating The Mechanism Of Resistance To Ido1 Enzyme Inhibitor Treatment In Human Glioblastoma, Kyla Shivakumar Hatton

Dissertations

Glioblastoma (GBM) is the most common and most aggressive form of adult cancer in the central nervous system, with GBM accounting for the majority of all malignant brain tumors. GBM is currently considered to be an incurable form of cancer, with over 14,000 patients diagnosed in the United States last year. Given the success of immunotherapy for treating other types of cancer, our group has investigated the possibility of therapeutically neutralizing immunosuppressive indoleamine 2,3 dioxygenase 1 (IDO1) in patients with GBM. Canonically, IDO1 is an immunosuppressive cytoplasmic enzyme that catalyzes the first step in metabolizing L-tryptophan into L-kynurenine (ie. ↓L-Trp→↑L-Kyn). …

Developing Chemically Defined Serum-Free Medium For Leukemic Blast And Stem Cell Expansion, Carmen Eva Finley

Dissertations

The relapse and chemotherapy resistance are the major challenges of acute myeloid leukemia (AML) treatment, driven by a rare population of leukemia stem cells (LSCs). LSCs are unique types of cells which evade standard chemotherapies and can regenerate AML post-treatment. Targeting LSC therapy remains limited, in part due to the lack of reliable in vitro AML culture systems to grow LSCs for drug discovery. This study aimed to engineer a chemically defined, serum-free 2D in vitro culture condition that supports either the expansion of leukemic blasts (LBs) or primary human LSCs by optimizing current protocols for hematopoietic stem cells (HSCs) …

Investigating Whether Txnrd2 Is A Therapeutic Target Against Triple Negative Breast Cancer Using African American-Derived Models, Keacha Chang

Dissertations

Despite similar breast cancer incidence rates, African American (AA) women experience a 40% higher mortality rate compared to Caucasian American (CA) women. This disparity is multifactorial and particularly pronounced in the Chicago area. AA women are twice as likely to be diagnosed with triple-negative breast cancer (TNBC), often at a younger age and with more aggressive disease. TNBC is a heterogeneous subtype lacking targeted therapies and is associated with the poorest prognosis among breast cancer types. Therefore, there is an urgent need for novel therapeutic strategies for TNBC, especially those tailored to AA patients. The thioredoxin pathway is essential for …

Examining Secretory Pathways In Inflammasome Activated Innate Immune Cells, Alejandra Castellanos Urquidez

Dissertations

Innate immune cells serve as the first line of defense by detecting pathogens through pathogen- and damage-associated molecular patterns (PAMPs and DAMPs). Recognition of PAMPs triggers the synthesis and secretion of pro-inflammatory proteins, with the inflammasome playing a key role in the secretion of interleukin-1β (IL-1β), a crucial part of the innate immune response. Upon inflammasome activation, the release of signal-peptide lacking cytoplasmic proteins such as IL-1β occurs through non-classical pathways known as unconventional protein secretion (UCPS), which vary depending on the cell type and stimulus which helps tailor the extent of pro-inflammatory protein secretion. Broadly, UCPS cargoes are released …

"I'M Not Having Fun Anymore": A Qualitative Analysis Of Gender And Harassment In Bars And Clubs, Phoebe Marie Jackson

Dissertations

Sexual harassment, while often spoken about in hushed tones or ignored altogether, happens frequently and often loudly. 66 percent of women who have experienced sexual harassment report that the harassment took place in a public space, such as work, school, or on the street (Kearl, 2018). Harassment is not discreet, but rather normalized, and those who experience it are expected to brush it off or take it in their stride. However, such harassment and subsequent dehumanization has a deteriorating effect on the mental well-being of those affected (Graham et. al., 2016). This study aims to hone in on the effect …

What Works In Telehealth Play Therapy? An Appreciative Heuristic Inquiry, Veronica Ann Ball

Dissertations

With the onset of coronavirus disease 2019 (COVID-19) in the United States in March 2020 (World Health Organization, 2020), professional counselors providing traditional in-person play therapy found themselves in a quandary regarding the delivery of services during a global pandemic (Evans, 2022; Mitchell, 2020; Whaibeh et al., 2020). Online counseling proffered a means to prevent the disruption of services, respond to the need for emerging counseling services, and comply with social restrictions (Evans, 2022). Prior to the pandemic, telehealth play therapy was used sparingly (Haslam & Harris, 2011; Smith et al., 2021), and many child-serving mental health professionals lacked training …

What About The Children? An Exploration Of Family Counselors' Play Therapy Training And Preparedness To Integrate Children Into Family Counseling, Patricia J. Walker Monical

Dissertations

Children are an important part of families, yet family counselor education programs often do not incorporate training for including children in family counseling. At some point in their careers, family counselors and therapists will encounter clients who have children 3–12 years old. The problem is that since these professionals often receive little to no training in play therapy and thus do not typically include young children in family therapy, these younger family members are often overlooked. Research has confirmed that, due to a lack of sufficient training and supervision in play therapy, many family therapists report feeling unprepared to work …

Pushing The Boundaries Of Large Language Models: Innovations And Limitations In Nlp, Finance, And Mathematics, A M Muntasir Rahman

Dissertations

Large Language Models (LLMs) have emerged as transformative tools across a spectrum of domains, yet their practical deployment reveals a blend of remarkable potential and notable limitations. This research explores innovative methodologies to extend the capabilities of LLMs while addressing critical challenges in their evaluation and application. By leveraging rule-based approaches, the in-context learning capabilities of LLMs, and human-in-the-loop validation across three focused studies, this research introduces robust strategies for dataset synthesis, model enhancement, and model assessment in three distinct domains: natural language processing, financial sentiment analysis, and mathematical reasoning

The first study proposes an efficient data augmentation framework, EASE, …

Game-Based Learning With Augmented Reality, Kantida Nanon

Dissertations

Augmented Reality (AR) technology provides an effective and controllable learning environment, especially for complicated, potentially dangerous, or critical content. Effective implementation of interaction and platforms for educational tools can maximize learner engagement and optimize the learning experience. This dissertation explores the potential of AR technology to enhance learning experiences across multiple platforms and subject areas, particularly within chemistry and mathematics. The dissertation is grounded in the field of Human-Computer Interaction (HCI) and explores the potential of AR to increase learner engagement, improve learning outcomes, and transform traditional pedagogical practices.

The dissertation is divided into two parts. The first part examines …

Ensemble Learning Models For Large-Scale Time Series Forecasting In Supply Chain, Minjuan Zhang

Dissertations

Machine learning and AI techniques are transforming supply chain forecasting, driven by the expanding availability of data assets. These advanced methods offer powerful opportunities to optimize management processes, reduce operational costs, and enhance strategic decision-making, which is crucial for enterprise success. However, conventional statistical approaches, such as Autoregressive Integrated Moving Average Models (ARIMA), dynamic regression, and Unobserved Component Models (UCMs)—which have long dominated time series forecasting—often fall short in accuracy and scalability. These traditional models face limitations in batch processing, handling large-scale data, addressing uncertainty-induced disruptions, and synchronizing demand-supply scenarios.

To address these challenges, a novel class of AI-powered ensemble …

Interactive Visualization Workflows For Mitigating Analytical Uncertainty, Kaustav Bhattacharjee

Dissertations

This dissertation takes a process-centric and stakeholder-first perspective for handling analytical uncertainty: the form of uncertainty that confronts data analysts' insight-generation processes in high-consequence decision-making scenarios. The cost of an incorrect decision when data is used for movie recommendations as opposed to when personal data is used to drive insights or when data-driven modeling is used to drive real-time decisions for maintaining the health of a grid are vastly different in terms of consequences. This dissertation looks at analytical uncertainty in two real-world scenarios: i) how sensitive information leakage can be prevented during the open data release process with data …

Crowd-Sourced Learning For Computer Graphics Applications, Yunhao Zhang

Dissertations

Computer Graphics (CG) revolves around virtual content creation using computational methods, spanning applications from games to visual effects. Typically, the creation of CG content is led by expert practitioners who guide computational algorithms towards satisfactory results. Thus, creating CG content often requires manual iterations encompassing algorithm design, parameter tuning, and aesthetic feedback. This work investigates how to leverage crowd-sourcing to streamline such creation processes, focusing on animation and simulation. In animation, a novel crowd-sourcing framework is proposed for combat animation, enabling users to analyze motion similarities, and retrieve matching motions using novel crowd-sourced motion features. Such features enable quantifying previously …

Representation Of Alaskan Native People In Nonprofit Leadership, Vanessa Smith

Dissertations

The nonprofit sector faces a significant issue: the underrepresentation of the communities it aims to serve, including Alaska Native communities. This research investigates the likely causes of this underrepresentation and explores potential solutions. It includes nine qualitative interviews with a majority of Alaskan Native leaders and consultations with other non-Native nonprofit leaders who have extensive experience in Alaska's nonprofit organizations.

This study arose from firsthand experience in an Anchorage, Alaska nonprofit, where the lack of Alaska Native representation in leadership roles within an organization meant to serve the Alaska Native community was evident. The research aimed to understand how well …

Beyond Average Effects In Education Research Syntheses: Explaining Heterogeneity Of Concept Mapping Research In Science Education Through Meta-Regression Modeling, Aaron Wenger

Dissertations

Contemporary education research seeks causal inferences in order to guide policy and practice. Often well-controlled quasi-experimental and experimental designs are used as they are very useful for supporting and contextualizing causal inferences. Nevertheless, individual studies, even high-quality, resource-intensive randomized controlled trials, are not able to establish generalized claims. Because primary studies vary over dozens of variables (e.g., grade, subject, duration) simply conducting additional primary studies cannot change this. Furthermore, the informal assessments of primary studies common in literature reviews are unable to resolve certain challenges (e.g., publication bias) that are described in the emerging field of meta-research. These challenges require …

A Phenomenological Study To Determine How Expert Avid Teachers Use Collaboration To Strengthen Student Metacognition And Student Self-Efficacy And Determine When It Occurs, Megan Hernandez

Dissertations

Purpose: The purpose of this phenomenological study was to determine how expert AVID teachers from the California Central Valley describe the use of collaboration to strengthen student metacognition and self-efficacy and how they describe the evidence that indicates metacognition and self-efficacy are occurring.

Methodology: Five Central California school districts were chosen to conduct the phenomenological study on expert AVID teachers. One to two AVID teachers from each of the five school districts were chosen in the study for eight participants. The expert AVID teachers were chosen for having at least five years of experience teaching AVID and being up to …

Examining Teachers’ Experiences In Fostering Social-Emotional Learning After Returning To In-Person Instruction In The Midst Of The Covid-19 Pandemic, Rosario Grajeda

Dissertations

Purpose: This qualitative phenomenological study examines how middle school teachers in Riverside County, California, support the social-emotional learning (SEL) needs of students as students returned to in-person instruction after the COVID-19 pandemic. Methodology: This qualitative study explores how Riverside County middle school teachers addressed students' social and emotional needs upon returning to in-person learning after COVID-19. Twelve teachers from local public middle schools (grades 6-8) participated in semi-structured interviews, answering ten questions. Data from interviews and artifacts were transcribed and analyzed using NVIVO software to identify recurring themes related to the study questions. Findings: The shared experiences of participants and …

An Exploratory Study Of The Barriers Of Pediatric Palliative Care Programs And Their Relationships To Funding, Mary Maureen Kirkpatrick Mclaughlin

Dissertations

This study, a sequential mixed methods design, used quantitative techniques and a qualitative, phenomenological approach. The quantitative phase addressed the research question: Does the reimbursement of services for the delivery of pediatric palliative care differ between types of funding, and is funding related to directors' perceptions of obstacles to the delivery of care? The qualitative phase addressed the research question: What are the barriers that CHI PACC directors' experience in their roles and how do they overcome them?

Administrators' Perception Of The Effectiveness Of Trauma-Informed Practices In Disciplinary Decisions, Rebecca Cahill

Dissertations

This research study examined administrators’ perceptions of the effectiveness of trauma-informed practices in disciplinary decision-making. Ten elementary school assistant principals were interviewed about their experiences with trauma-informed practices following a student referral. The participants also submitted behavioral expectation matrices and discipline flowcharts for analysis. The participants recognized and valued the underlying elements of trauma-informed practices (relationships, context, support, and cultural factors). However, they lack a clear understanding of and processes for full implementation of trauma-informed practices into disciplinary decision-making. Given the increase in negative student behavior and teacher requests for support, more research is needed to identify a process(es) for …