Digital Commons Network^™

A New Rough Wall Layer Modeling For Turbulent Flows Using The Brinkman Equation, Meng-Huang Lu

Dissertations

No abstract provided.

Making The Difference In High Poverty; High Achieving Urban Elementary Schools: Selected Principal's Perspectives, Penny Larsen

Dissertations

This study is a mixed-method design focusing on ten White and ten non-White elementary principals working in urban areas. The qualitative methodology uses interviews and observations to examine how principals conceptualize the student achievement gaps and through what practices do they attempt to remedy the condition. The quantitative data resulted from the Quick Discrimination Index and relied on descriptive statistics. The primary audience for this study includes PK-12 public school administrators, particularly those in urban high-diversity, high-achieving schools.

The investigation (1) examined cultural differences between White and non-White administrators and their student constituency in terms of ethnicity and language use, …

A Comparison Of Maintenance-Training Methods For Children Diagnosed With Autism, Nicholas L. Weatherly

Dissertations

The current study evaluated the effects of two different maintenance-training methods and one control condition on skill maintenance within a public-school classroom for children diagnosed with autism. The two training methods involved the use of either a continuous-reinforcement schedule or a thinned partial-reinforcement schedule during 20 overlearning training sessions following skill acquisition. The control condition did not involve any overlearning following skill acquisition. Three children were each taught two curricular programs, with each program involving the two training methods and the control condition using a multielement design. Overlearning using a thinned partial-reinforcement schedule reliably produced greater maintenance across all participants, …

Physical Education Content Knowledge And Physical Activity Behaviors Of Mississippi High School Students, Christina Leigh Lumpkin Martin

Dissertations

The present study investigated physical education content knowledge, physical activity behaviors, and body mass indexes of 386 Mississippi ninth (n=236 ) and twelfth (n=150) grade students with a goal of establishing evidence-based needs to modify physical education curricula. Results of this study suggested that a significant, direct relationship did exist in the Assessment of Sub-disciplinary Knowledge in Physical Education: Exercise Physiology (ASK PE: EXP);(Ayers, 2004) scores and scores from the Modifiable Activity Questionnaire for Adolescents (M4<2^4);(Aaron & Kriska, 1997) for both ninth and twelfth grade students. Findings also suggested that physical education content knowledge (exercise physiology) is more likely to contribute to twelfth grade reported physical activity scores than ninth grade reported physical activity scores. However, ninth graders were more active than twelfth graders. This is possibly explained by the small difference (5%) in ASK PE: EXP scores between ninth (M ASK PE: EXP score = 52%, SD=.22) and twelfth graders (M ASKPE: EXP score = 57%, SD = .21). As a whole, results indicated that Mississippi ninth and twelfth grade students' average ASKPE: EXP score was lower (M = 53%, SD = .22) than students in 16 other states (M = 62%, SD = 7.65). Further, majority of Mississippi high school students are performing significantly below the established, research-based cutoff score of 62% (observed N below 62% = 236 and observed N above 62% = 150). This is notable, because findings also suggested that students who scored higher (M knowledge = 76%, SD = .08);(M activity = 8.6 hours/week, SD = 9.7) or above 62% on the ASK PE: EXP were more likely to be active during a weekly basis compared to those who scored lower (M knowledge = 39%, SD = .14);(M activity = 5.8 hours/week, SD = 9.8) or below a 62% on the ASK PE: EXP. With this noted, it was recommended that Mississippi high schools evaluate the current physical education programs, and strive to implement curricula that can provide students with the necessary knowledge and skills to make lifelong healthy decisions.

Identification Of Two Distinct Glutaminyl Cyclase Isoforms In Drosophila Melanogaster, Amanda Thigpen Parker

Dissertations

Sequence analyses revealed two putative glutaminyl cyclase genes in Drosophila melanogaster with greater than 60% amino acid sequence identity to previously identified glutaminyl cyclase in humans. Expression, purification, and characterization of both putative proteins revealed two enzymatically active glutaminyl cyclase enzymes. Comparison of the Drosophila melanogaster glutaminyl cyclase enzymes to the published human glutaminyl cyclase revealed the enzymes were very similar. The Km values obtained were identical to those of human glutaminyl cyclase for three different substrates tested. However, the Drosophila glutaminyl cyclases demonstrated lower turnover numbers. Both Drosophila glutaminyl cyclase isoforms were inhibited by imidazole, imidazole derivatives, and metal …

Knowledge-Based Analysis Of Genomic Expression Data By Using Different Machine Learning Algorithms For The Purpose Of Diagnostic, Prognostic Or Therapeutic Application, Venkata Jagan Mohan Thodima

Dissertations

With more and more biological information generated, the most pressing task of bioinformatics has become to analyze and interpret various types of data, including nucleotide and amino acid sequences, protein structures, gene expression profiling and so on. In this dissertation, we apply the data mining techniques of feature generation, feature selection, and feature integration with learning algorithms to tackle the problems of disease phenotype classification, clinical outcome and patient survival prediction from gene expression profiles.

We analyzed the effect of batch noise in microarray data on the performance of classification. Batchmatch, a batch adjusting algorithm based on double scaling method …

The Impact Of Gender Socialization On Women?S Learned Technological Helplessness And Its Andragogical Implications, Joy Elise Harris

Dissertations

This research investigated a proposed construct of learned technological helplessness (LTH) in female adult learners, which is believed to be impacted by socialization into traditional gender roles, teacher modeling, and age. A two-pronged approach was used to examine women?s attitudes and beliefs about their abilities to use technology as a learning and personal productivity tool. Participants were females, over age 18, on two campuses of a public Midwest research university. Prior to the primary research, a pilot study (n=204) was undertaken for the purpose of creating a teacher modeling instrument, which measured how teachers model the use of technology. The …

Relation Of Family Functioning To Treatment Outcomes In Day And Residential Programs: A Clinical Study With Emotionally Disturbed Adolescents, Utpala Shanker

Dissertations

Residential and day facilities are important providers of treatment for seriously emotionally disturbed adolescents. The primary difference between the two types of treatment programs is that adolescents attending day treatment reside with their families while those in residential programs live at the treatment facility. Very few studies have addressed the relation of family functioning to treatment outcomes for adolescents. Furthermore, extant research has not investigated whether the relation of family functioning to treatment outcomes is different for adolescents in residential and day programs, This study proposed that adolescents from severely dysfunctional families at admission would have better outcomes in their …

Towards Development Of A Fully Synthetic Conjugate Vaccine: Investigation Of Structural Analogs Of Streptococcus Pneumoniae Serogroup 6, Archana R. Parameswar

Dissertations

Involvement of complex glycostructures in a variety of damaging and healing processes has already been acknowledged by development of carbohydrate-based vaccines and therapeutics. The bacteria Streptococcus pneumoniae (SPn) have become one of the most frequent causes of pneumonia, bacteremia, and meningitis in the elderly, immunocompromised, and, especially, in young children. SPn has one of the largest public health and economic impacts amongst all bacterial infectious diseases. Over 2 million children die annually worldwide due to pneumonia, accounting for almost 20% of deaths under age five with more than half of these deaths attributed to SPn. Amongst over ninety elucidated SPn …

Synthesis Of Α-Hydroxy And Fluoro Phosphonates And Cyclic Ether-Containing Natural Products, Nongnuch Sutivisedsak

Dissertations

A number of important classes of natural product (eg. amphidinolide C, (-)-centrolobine, etc) contain common structural features of tetrahydrofurans and tetrahydropyrans. This study involved the development of stereoselective mothods for the synthesis of tetrahydrofurans and tetrahydropyrans including the application of allylic hydroxy phosphonates and their derivatives as chiral, non racemic building blocks for the synthesis of biological active molecules. The enantiomeric excess of non racemic α-hydroxy phosphonates and carbonate derivatives prepared via the asymmetric Pudovik reaction can be improved by kinetic resolution. Both chemical and enzyme catalysts were utilized in the kinetic resolution of phosphonates. Enantioselective acylation of a variety …

The Effect Of Active Site Mutations On The Homodimeric Behavior Of The Pvuii Restriction Endonuclease, Grigorios A. Papadakos

Dissertations

The PvuII restriction endonuclease, a homodimer of two 18 kDa subunits, belongs to the type II family of restriction enzymes. Located in the active site of PvuII, Tyrosine 94 has previously been shown to be involved in the metal ion binding by the enzyme. The profile of the Ca2+ dependence of the DNA binding to the Y94F variant is shown to be clearly biphasic. The application of a sequential binding model yielded a coupling energy (ΔGcoop) at -0.54 for the upper phase and -1.15 kcal/mole for the lower phase. The similar metal binding pattern between the Y94F and the WT …

Mechanistic Studies Of Specific Dna Cleavage By Pvuii Restriction Endonuclease, Xie Fuqian

Dissertations

PvuII restriction endonuclease is a homodimeric protein which recognizes and cleaves the palindromic sequence (CAG?CTG) in the presence of Mg(II) ions. Starting with PvuII as a model system, pKa calculations with crystallographically defined metal ligated water are applied to PD?D/ExK motif metallonucleases in order to investigate the activation of nucleophile in metal dependent DNA hydrolysis. These results establish the electrostatic contributions of the metal ions and the conserved Lys in lowering water pKa. The calculated pKa values of metal ligands have been used to simulate the pH dependence of Mg(II) binding to PvuII. The bell shaped pH-rate profile is dissected …

A Study Of The Effectiveness Of A School District's Mentoring / Professional Development Plan For Beginning Teachers, Jason Sefrit

Dissertations

The purpose of the study of the mentoring I professional development program within the teaching profession was to determine the extent and perceived value of the existing formal mentoring program in the Fort Zumwalt School District. The study found that the district's mentoring and professional development program for new teachers is effective as perceived by both beginning teachers and their administrators. The instrument used in this study was a survey designed by the District and distributed to beginning teachers who finished their first year of teaching and the formal mentor program during the 2002-2003 through the 2006-2007 school years. Surveys …

A Study Of The Effectiveness Of A School District's Mentoring / Professional Development Plan For Beginning Teachers, Kim Carter

Dissertations

The purpose of the study of the mentoring / professional development program within the teaching profession was to determine the extent and perceived value of the existing formal mentoring program in the Fort Zumwalt School District. The study found that the district's mentoring and professional development program for new teachers is effective as perceived by both beginning teachers and their administrators. The instrument used in this study was a survey designed by the District and distributed to beginning teachers who finished their first year of teaching and the formal mentor program during the 2002-2003 through the 2006-2007 school years. Surveys …

Reproductive And Social Dynamics Of A Lek Breeding Bird, Thomas Brandt Ryder

Dissertations

Sociality and the unequal apportionment of reproductive success among social individuals is a common characteristic of many vertebrate taxa. To date, our understanding of what factors drive high variance in reproductive success (i.e., intra vs. inter-sexual selection) and which male attributes contribute to that variance, are still fragmentary for most species. Moreover, how social structure interacts with individual behavior and fitness remains understudied despite its potential importance to the evolution of cooperation. This dissertation research focused on understanding this complex synergistic interplay between social and reproductive dynamics in a lek-breeding bird, the wire-tailed manakin. The first chapter examines the complex …

Remote Sensing Solutions For Estimating Runoff And Recharge In Arid Environments, Adam M. Milewski

Dissertations

Efforts to understand and to quantify the interplay between precipitation, runoff, and recharge are often hampered by the paucity of appropriate monitoring systems. We developed methodologies for rainfall-runoff and groundwater recharge computations that heavily rely on observations extracted from a wide-range of global remote sensing data sets (TRMM, SSM/I, AVHRR, and AMSR-E,) using the arid Sinai Peninsula (SP; area: 61,000 km²) and the Eastern Desert (ED; area: 220,000 km²) of Egypt as our test sites. A two-fold exercise was conducted. Temporal remote sensing data (TRMM, AVHRR and AMSR-E) were extracted from global data sets over the …

Exploration Of The Chemical And Biological Processes Through Molecular Dynamics Simulation And Blocklocalized Wavefunction Method, Yuchun Lin

Dissertations

Computer simulation plays a crucial role in interpreting, unifying and guiding experimental observations. In this dissertation, molecular dynamics (MD) simulations and the block-localized wavefunction (BLW) method have been used to explore the chemical and biological processes.

Detailed MD simulations were performed to study the transportation of NH₄⁺, NH₃ and H₂O through the Escherichia coli ammonium transporter (AmtB) membrane protein. A periplasmic recruitment vestibule was identified and the entrance of an NH₄⁺ into this vestibule requires only 3.1 kcal/mol. In the end of this vestibule, the phenyl ring of Phe107 dynamically opens and …

A Comparison Of Three Training Methods On The Acquisition And Retention Of Automotive Product Knowledge, Rhiannon M. Fante

Dissertations

The purpose of this study was to compare the effects of a traditional (non-fluency) web-based training program with and without study objectives with a web-based fluency-building training program on the acquisition and retention of automotive product knowledge. The effects of the training conditions were assessed by how accurately and quickly participants responded on a product knowledge test immediately after training, four weeks after training, and eight weeks after training. A three-group between subjects design was used with 20 college students in each group. Results indicated that participants in the fluency training group were more accurate and fluent immediately after training, …

Synthesis, Characterization, And Catalytic Application Of Gold Nanoparticles, Junhyung Kim

Dissertations

Properties of nanometer-sized gold(Au) particles, especially those that are protected by a monolayer coating of thiolate ligands, called 'Monolayer Protected Clusters' (MPCs), are of rigorous multidisciplinary interest for their potential applications in catalysis and electronics due to their variation with size.

In larger core diameter sizes (>1.5nm) AuMPCs show metallic behavior as observed from electrochemical measurements. On the other hand, sub-nanometer ([approximate]1.1nm) AuMPCs exhibit molecule-like electronic behavior which is typical of Au38 nanoparticles. The various alkane chain thiols(C4 S-C12 S) capped Au38 MPCs have been examined with independent analytical tools, producing a remarkably consistent picture of these materials.

The …

Collective Bargaining In Public Schools: Superintendents' Perspective, Kyle W. Mayer

Dissertations

The purpose of this study was to explore how selected superintendents are experiencing the collective bargaining process. Exploration included an examination of the various roles that selected superintendents have played in the collective bargaining process within rural and suburban school districts in Michigan.

Furthermore, exploration included thematic areas of greatest challenges facing superintendents in recent collective bargaining negotiations. Particular emphasis was given to the style of collective bargaining environment that superintendents reported as most conducive to successful contract negotiations. In addition, the rising cost of health care benefits was a significant point of emphasis within this study.

Twenty-six superintendents from …

The Role Of Short Term Synamptic Plasticity In Temporal Coding Of Neuronal Networks, Lakshmi Chandrasekaran

Dissertations

Short term synaptic plasticity is a phenomenon which is commonly found in the central nervous system. It could contribute to functions of signal processing namely, temporal integration and coincidence detection by modulating the input synaptic strength. This dissertation has two parts. First we study the effects of short term synaptic plasticity in enhancing coincidence detecting ability of neurons in the avian auditory brainstem. Coincidence detection means a target neuron has a higher firing rate when it receives simultaneous inputs from different neurons as opposed to inputs with large phase delays. This property is used by birds in sound localization. When …

Projecting Land Use Changes Using Parcel-Level Data : Model Development And Application To Hunterdon County, New Jersey, Florencio C. Ballesteros Jr.

Dissertations

This dissertation is to develop a parcel-based spatial land use change prediction model by coupling various machine learning and interpretation algorithms such as cellular automata (CA) and decision tree (DT). CA is a collection of cells that evolves through a number of discrete time steps according to a set of transition rules based on the state of each cell and the characteristics of its neighboring cells. DT is a data mining and machine learning tool that extracts the patterns of decision process from observed cell behaviors and their affecting factors. In this dissertation, CA is used to predict the future …

Density Relaxation Of Granular Matter Through Monte Carlo And Granular Dynamics Simulations, Oleksandr M. Dybenko

Dissertations

Granular materials are the principal ingredients of the industrial complex involved with the handling and processing of bulk solids including pharmaceuticals, chemicals, agricultural and mining materials. Despite the enormous importance of these materials in society, their behavior is not well-understood; in fact, there is no known model available that is capable of predicting the wide range of phenomenon that have been observed. One of the most important of these is known as density relaxation. Here, a granular material undergoes an increase in solids fraction as a result of the application of discrete taps or continuous vibrations.

In this dissertation, the …

Roles Of Gap Junctions In Neuronal Networks, Joon Ha

Dissertations

This dissertation studies the roles of gap junctions in the dynamics of neuronal networks in three distinct problems. First, we study the circumstances under which a network of excitable cells coupled by gap junctions exhibits sustained activity. We investigate how network connectivity and refractory length affect the sustainment of activity in an abstract network. Second, we build a mathematical model for gap junctionally coupled cables to understand the voltage response along the cables as a function of cable diameter. For the coupled cables, as cable diameter increases, the electrotonic distance decreases, which cause the voltage to attenuate less, but the …

Synthesis And Characterization Of Plasma Enhanced Chemically Vapor Deposited Tantalum Films, Weizhong Chen

Dissertations

A low temperature inorganic plasma-enhanced chemical vapor deposition (PECVD) process has been developed for the growth of Ta using tantalum pentachloride (TaC15) as the preferred precursor and hydrogen as the reactant gas. Ta coatings were deposited at substrate temperature of 370-400 °C, reactor working pressures of 0.7-2 Ton, hydrogen carrier flow rate of 10-20 sccm, hydrogen reactant flow rates of 500 sccm, and plasma power ranging from 60 to 100W. Ta coatings were characterized with respect to their chemical, structural, and morphological properties by Auger electron spectroscopy (AES), x-ray diffraction (XRD), atomic force microscopy (AFM), x-ray photoelectron spectroscopy (XPS), scanning …

Appropriation Of Privacy Management Within Social Networking Sites, Catherine Dwyer

Dissertations

Social networking sites have emerged as one of the most widely used types of interactive systems, with memberships numbering in the hundreds of millions around the globe. By providing tools for their members to manage an ever-changing set of relationships, social networking sites push a constant expansion of social boundaries. These sites place less emphasis on tools that limit social boundaries to enable privacy.

The rapid expansion of online social boundaries has caused privacy shockwaves. Privacy offline is enabled by constraints of time and space. Online, powerful search engines and long term digital storage means private data have no expiration …

Instabilities Of Volatile Films And Drops, Nebojsa Murisic

Dissertations

We report on instabilities during spreading of volatile liquids, with emphasis on the novel instability observed when isopropyl alcohol (IPA) is deposited on a monocrystalline silicon (Si) wafer. This instability is characterized by emission of drops ahead of the expanding front, with each drop followed by smaller, satellite droplets, forming the structures which we nickname “octopi” due to their appearance. A less volatile liquid, or a substrate of larger heat conductivity, suppress this instability. In addition, we examine the spreading of drops of water (DJW)-JPA mixtures on both Si wafers and plain glass slides, and describe the variety of contact …

Signal Transmission In Epithelial Layers, Filippo Posta

Dissertations

Cell signaling is at the basis of many biological processes such as development, tissue repair, and homeostasis. It can be carried out by different mechanisms. Here we are focusing on ligand mediated cell-to-cell signaling in which a molecule (ligand) is free to move into the extra-cellular medium. On the cell layer surface, it can bind to its molecule-specific receptors located on the cell plasma membrane. This mechanism is the subject of many experimental and theoretical studies on many model biological systems, such as the follicular epithelium of the Drosophila egg, which motivates this work.

Here, we present a general mathematical …

Data Allocation In Disk Arrays With Multiple Raid Levels, Jun Xu

Dissertations

There has been an explosion in the amount of generated data, which has to be stored reliably because it is not easily reproducible. Some datasets require frequent read and write access. like online transaction processing applications. Others just need to be stored safely and read once in a while, as in data mining. This different access requirements can be solved by using the RAID (redundant array of inexpensive disks) paradigm. i.e., RAIDi for the first situation and RAID5 for the second situation. Furthermore rather than providing two disk arrays with RAID 1 and RAID5 capabilities, a controller can be postulated …

Production Of Nanocrystalline Rdx By Ress : Development And Material Characterization, Victor Stepanov

Dissertations

The aim of the present work was to address the hazardous vulnerability of energetic materials to accidental initiation. An improved form of the explosive RDX with a significantly reduced sensitivity to stimuli including shock and impact was sought. The direction of this research was to investigate the effect of RDX crystal size reduction down to nano-scale dimensions on the sensitivity characteristics. Although size reduction of energetic crystals has been demonstrated often to result in a sensitivity reduction, the effect at the nano-scale particle size has not been investigated.

To generate nanocrystalline RDX a recrystallization process was developed based on rapid …