Digital Commons Network^™

An Innovative Protective Jacket For Structures Subject To Blast Loads: A Comprehensive Experimental And Simulation Study, Nicholas J. Carlson

Dissertations

As the importance of protective engineering and multi-hazard mitigation design has grown in recent years, the development of an effective structural protection system that aids in the preservation of life safety during blast events is an important topic of research in structural engineering. This protection is especially vital for blast and explosion mitigation, where a vehicle-borne bomb or an improvised explosive device can readily cause an under-designed structure with insufficient redundancy to undergo progressive collapse due to the removal of its first-floor columns. An especially pressing research need is the consideration of structures that require blast protection, but—due to time …

Novel Color And Local Image Descriptors For Content-Based Image Search, Sugata Banerji

Dissertations

Content-based image classification, search and retrieval is a rapidly-expanding research area. With the advent of inexpensive digital cameras, cheap data storage, fast computing speeds and ever-increasing data transfer rates, millions of images are stored and shared over the Internet every day. This necessitates the development of systems that can classify these images into various categories without human intervention and on being presented a query image, can identify its contents in order to retrieve similar images.

Towards that end, this dissertation focuses on investigating novel image descriptors based on texture, shape, color, and local information for advancing content-based image search. Specifically, …

Mechanical, Electronic And Optical Properties Of Multi-Ternary Semiconductor Alloys, Dongguo Chen

Dissertations

The ability to obtain tunable properties with composition makes multi-ternary alloys extremely useful for a variety of applications in semiconductor devices and is of significant interest in experimental and theoretical research. This dissertation investigates the mechanical, electronic and optical properties of multi-ternary, i.e., binary, ternary and quaternary, semiconductor alloys using analytical methods and first-principles calculations.

For the calculations of mechanical properties, existing models on the average shear modulus of III-V & II-VI binary semiconductors are revised. New expressions are developed for the average Young’s modulus as well as the shear modulus and Young’s modulus on (111) plane for these compounds. …

The Application Of Bayesian Adaptive Design And Markov Model In Clinical Trials, Xiaoyu Lu

Dissertations

In this research, two new designs in clinical trials are proposed. The first problem is a new Bayesian adaptive dose-finding design and its application in an oncology clinical trial. This design is used for phase IB studies with the biomarker as the endpoint and with the fewer patients. The second problem is another new Bayesian adaptive dose-finding design with longitudinal analysis and its application in phase II depression clinical trial. This design is best fit for phase II dosing-finding clinical trials with clinical endpoints. MTD information has been obtained before the trials.

In adaptive dose-finding clinical trials, the strategy is …

Developing Crash Modification Factors For Operational Parameters On Urban Freeways, Eugene Vida Maina

Dissertations

Studies have shown that, roadway safety has become an intensively investigated topic with the objective of improved understanding of the factors that cause crashes to occur. However, it has been shown that as traffic volumes continue to increase across the United States, 52% of drivers feel less safe on the roads today more than they did five years ago and that the American public feels that traffic safety is a serious problem that needs both the government and media to pay more attention to this issue.

In response to these public and driver grievances, State and National transportation agencies have …

The Effect Of Nanoclays On The Properties Of Aspirin Modified Enteric Polymer Prepared By Hot-Melt Mixing, Nonjaros Chomcharn

Dissertations

Melt mixing in batch equipment or continuous extruders is a technique that recently gained the attention of the pharmaceutical industry. This dissertation investigates two controlled-release drug delivery systems. The first system, namely the enteric matrix, contains an active pharmaceutical ingredient (API) and plasticizer in an enteric polymer while in the second system a nanoclay is added to the enteric matrix, to produce a polymer nanocomposite. The first system employs hot-melt mixing to prepare a modified enteric matrix, as a delayed-release dosage form. Different concentrations of aspirin (ASP) ranging from 10 – 30% w/w are melt-mixed with a plasticized Eudragit® …

Study Of Deep Level Defects Of N+-Cds/P-Cdte Solar Cells, Poonam Rani Kharangarh

Dissertations

Among various photovoltaic materials, polycrystalline cadmium telluride thin film is now the most promising material, due to its low production cost excellent stability and reliability. Current-voltage and capacitance-voltage measurements of CdTe photovoltaic devices at different temperatures can provide valuable information about non-idealities in the n-p semiconductor junction. There are certain limitations which limit the efficiency of CdTe solar cells. There is no real distinction between defects and impurities in CdTe solar cells as both act as beneficial dopants or detrimental traps unlike Si where intentional shallow dopants and traps are distinctly different. Therefore, the role of defect states on CdTe …

High Performance Digital Signal Processing: Theory, Design, And Applications In Finance, Mustafa Ugur Torun

Dissertations

The way scientific research and business is conducted has drastically changed over the last decade. Big data and data-intensive scientific discovery are two terms that have been coined recently. They describe the tremendous amounts of noisy data, created extremely rapidly by various sensing devices and methods that need to be explored for information inference. Researchers and practitioners who can obtain meaningful information out of big data in the shortest time gain a competitive advantage. Hence, there is more need than ever for a variety of high performance computational tools for scientific and business analytics. Interest in developing efficient data processing …

Escherichia Coli 2-Oxoglutarate Dehydrogenase Multienzyme Complex: E1 And E2 Substrate Specificty, E1 Carboligase Activity, And E2 Interchain Succinyl Transfer, Da Jeong Shim

Dissertations

Escherichia coli (E. coli) 2-oxoglutarate dehydrogenase multienzyme complex (OGDHc) contains three components: a thiamin di phosphate (ThD P) dependent 2-oxogl utarate dehydrogenase (E1 o), a di hydrol i poylsucci nyl transferase (E2o), and a di hydrol i poyl dehydrogenase (E3). The first two components carry out the principal reactions for succinyl CoA formation while the third one reoxidizes dihydrolipoamide to lipoamide. This mechanism is similar to other 2-oxoacid dehydrogenase complexes, including pyruvate dehydrogenases (PDHc) and branched-chain dehydrogenases.

E1o of the E. coli OGDHc was engineered to accept unnatural substrates. The natural substrate for E1 o is 2-oxogl utarate …

Hosx: Hospital Operations Excellence Model, Shivon S. Boodhoo

Dissertations

Hospital performance can be evaluated in four categories: (i) quality of care, (ii) process of care (iii) financial and (iv) operations productivity. Of these, ‘quality of care’ is the most widely reported and studied measure of performance, and focuses primarily on the clinical outcomes of the patient. In contrast, operations productivity and efficiency is the least studied measure, and currently there is limited ability to evaluate how efficiently the hospital has used its resources to deliver healthcare services. Cost containment in the healthcare industry is a challenging problem, and there is a lack of models and methods to benchmark hospital …

Computational Thermochemistry Of Hydrocarbons, Oxygenates, Cyclic Alkanes, And Furans, Jason Michael Hudzik

Dissertations

Fundamental thermochemical properties including enthalpies (ΔH°_{f 298}), entropies (S° (T)), heat capacities (C_p(T)), and bond dissociation energies (BDEs) for several common and complex hydrocarbon fuel species are determined using computational chemical methods. ΔH° _{f 298} values are calculated using work reactions with the B3LY P (6-31 G(d,p) and 6-311G(2d,2p) basis sets), CBS-QB3, and G3MP2B3 calculation methods. Structures, moments of inertia, vibrational frequencies, and internal rotor potentials are calculated for contributions to entropies and heat capacities. Kinetic rate parameters are calculated for hydrogen abstraction and chemical activation reactions.

Recommended ΔH° …

A Statistical Study Of Plasmawaves And Energetic Particles In The Outer Magnetosphere, Kyungguk Min

Dissertations

The Earth magnetosphere contains energetic particles undergoing specific motions around Earth’s magnetic field, and interacting with a variety of waves. The dynamics of energetic particles are often described in terms of three kinds of adiabatic invariants. Energetic electrons are often unstable to the whistler-mode chorus waves, and ions, to the electromagnetic ion cyclotron (EMIC) instability. These waves play an important role in the dynamics of the magnetosphere by energizing electrons to form a radiation belt, extracting energy from the hot, anisotropic ions and causing pitch angle scattering of energetic ions and relativistic electrons into the loss cone. EMIC waves correspond …

Foaming Of Amorphous Drug Delivery Systems Prepared By Hot Melt Mixing And Extrusion, Graciela Terife

Dissertations

Currently there is considerable interest from both academe and pharmaceutical industry in exploring foaming processes and their products in drug delivery applications. However, there is still little knowledge of the impact of the morphology of the foamed structures on the performance of drug products in spite of some publications in this area. Therefore, the main objective of this dissertation is to gain a fundamental understanding of the correlation between foam morphology and performance of amorphous drug delivery systems, which are comprised of an Active Pharmaceutical Ingredient (API) and Polymer excipient.

The Hot Melt Extrusion (HME) process is used to compound …

Mathematical Models For Bistable Nematic Liquid Crystal Displays, Chenjing Cai

Dissertations

Bistable Liquid Crystal Displays (LCDs) offer the potential for considerable power savings, compared with conventional (monostable) LCDs. The existence of two (or more) stable field-free states that are optically-distinct means that contrast can be maintained in a display without an externally-applied electric field. An applied field is required only to switch the device from one state to the other, as needed. This dissertation focuses on theoretical models of a possible bistable nematic device, whose operating principle relies on controlling surface anchoring conditions. Switching between the two stable steady states is achieved by application of a transient electric field. A 1D …

Thermochemistry Reaction Paths And Oxidation Kinetics On Ketonyl And Aldehydic Nitrogen Oxides, Propene And Isooctane: A Theoretical Study, Suarwee Snitsiriwat

Dissertations

Thermochemical properties for several atmospheric and combustion related species are determined using computational chemical methods coupled with fundamentals of thermodynamics and statistical mechanics. Enthalpies of formation (ΔH_f°₂₉₈) are determined using isodesmic reaction analysis at the CBS-QB3 composite and the B3LYP density functional methods. Entropies (S°₂₉₈) and heat capacities (Cp°(T)) are determined using geometric parameters and vibration frequencies; internal rotor contributions are included in S and Cp(T) values in place of torsion frequencies. Kinetic parameters are calculated versus pressure and temperature for the chemical activated …

Investigations Into B-O Defect Formation-Dissociation In Cz-Silicon And Their Effect On Solar Cell Performance, Prakash M. Basnyat

Dissertations

About 30% of the total market share of industrial manufacture of silicon solar cells is taken by single crystalline Czochralski (CZ) grown wafers. The efficiency of solar cells fabricated on boron-doped Czochralski silicon degrades due to the formation of metastable defects when excess electrons are created by illumination or minority carrier injection during forward bias. The recombination path can be removed by annealing the cell at about 200° C but recombination returns on exposure to light.

Several mono-crystalline and multi-crystalline solar cells have been characterized by methods such as laser beam induced current (LBIC), Four-Probe electrical resistivity etc. to better …

Stability And Precipitation Of Diverse Nanoparticles, Chintal Desai

Dissertations

Nanotechnology is a rapidly growing industry that is exploiting the novel characteristics of materials manufactured at the nanoscale. Carbon based nanomaterials such as Carbon Nanotubes (CNTs) and Detonation Nanodiamond (DND) possess unique properties and find a wide range of industrial applications. With the advent of mass production of such materials, there is a possibility of contamination of water resources. Depending on the surface properties and structures, they might aggregate and settle down, or be dispersed and transported by the water. Therefore, there is a need to develop an understanding of the fate of such materials in aqueous media. The understanding …

A Numerical Method For Electro-Kinetic Flow With Deformable Interfaces, Manman Ma

Dissertations

We consider two-phase flow of ionic fluids whose motion is driven by an imposed electric field. At a fluid-fluid interface, a screening cloud of ions develops and forms an electro-chemical double layer or ‘Debye layer’. The applied electric field acts on the ionic cloud it induces, resulting in a strong slip flow near the interface. This is known as ‘induced-charge electro-kinetic flow’, and is an important phenomenon in microfluidic applications and in the manipulation of biological cells. The models with two different cases including the fast or slow charging time scales are studied both analytically and numerically. We address a …

Study Of Elementary Reactions Of Combustion Importance At Elevated Temperatures And Pressures, Manuvesh Sangwan

Dissertations

The aim of the present study is to study the kinetics of elementary reactions of combustion importance at elevated temperatures and pressures. High pressure is encountered in many systems of practical importance such as internal combustion engines and rocket combustion chambers. Several reactions of OH, CH₃ and HO₂ radicals are studied. The pressure range covered in this study is 1 - 100 bar and the temperature range is 292 - 834 K. The experimental approach used is laser photolysis coupled to UV transient absorption spectroscopy. A unique high pressure heatable flow reactor is employed and a novel approach …

Application Of Hydrogen Peroxide As Brown Tide Bloom Control Agent, Varunpreet Randhawa

Dissertations

Harmful algal blooms (HABs) are growing problem across the globe. One such HAB that’s recurring in the coastal waters of New York and New Jersey since mid-1980s, and has been reported in other countries recently, is brown tide bloom. The causal organism is a minute pel agophyte (cell diameter ~- 2µ m) Aureococcus anophagefferens. The brown tide bloom has been responsible for the severe ecological damage and economic loss (e.g. shellfishery) in the affected areas. This research focuses on finding a method to control brown tide blooms and explores the potential of natural chemical biocide hydrogen peroxide (H_{2 …}

Gp Representation Space Reduction Using A Tiered Search Scheme, John Joseph Aleshunas

Dissertations

The size and complexity of a GP representation space is defined by the set of functions and terminals used, the arity of those functions, and the maximal depth of candidate solution trees in the space. Practice has shown that some means to reduce the size or bias the search must be provided. Adaptable Constrained Genetic Programming (ACGP) can discover beneficial substructures and probabilistically bias the search to promote the use of these substructures. ACGP has two operating modes: a more efficient low granularity mode (1st order heuristics) and a less efficient higher granularity mode (2nd order heuristics). Both of these …

Synthesis And Characterization Of Luminescent Cyclic Germanium Compounds, Teresa Lynn Bandrowsky

Dissertations

The vision in the field of organic electronics is the realization of flexible, easily manufactured, low cost optoelectronics for use in organic light emitting diodes (OLEDs) for large area displays and lighting applications, organic photovoltaic cells, and organic field-effect transistors. The active layers within such devices are composed of semiconducting small molecules or polymers. The rich chemistry of new π-conjugated materials holds the key to continued progress by allowing the material properties of organic semiconductors to be readily tuned towards application specific demands. At the core of this subject matter is how to modify the electronic structures of π-conjugated molecules …

The Investigation Of Iron(Ii) Complexes And Their Catalytic Applications, Matthew Joseph Lenze

Dissertations

Several new η5-indenyl (Ind) complexes of iron featuring phosphinooxazoline (PHOX) ligands were synthesized and spectroscopically characterized and in a few cases structurally. The complexes were synthesized using phosphinooxazoline ligands and the corresponding iron precursor [Fe(η5-Ind) I(CO)2], yielding novel piano-stool iron complexes of the general formula [Fe(η5-Ind)(CO)(PHOX)]+ in 73% to 81% isolated yields. The complexes were tested for their efficacy in a carbon-carbon bond formation known as the Mukaiyama aldol reaction. The [Fe(η5-Ind)(CO)(PHOX)]+ complexes were capable of activating the carbonyl of aromatic aldehydes towards by attack 1-(tertbutyldimethylsilyloxy)-1-methoxyethene to form the expected silyl protected β-hydroxyesters. In these complexes, the η5-η3 haptotropic shift …

Developmental Reading Course Repeaters With Significant Cognitive Disabilities At The Community College: Evaluating Enrollment Motivations And Goals, Juliet Katherine Lilledahl Scherer

Dissertations

This study investigated the enrollment motivations of developmental reading course repeaters at St. Louis Community College (STLCC) who are judged to be highly unlikely to exit the developmental reading sequence by their instructors and/or counselors in the Access Office, the office that assists students with disabilities. This three-phase study consisted of interviewing STLCC students in this population (Phase I) and surveying their parents (Phase II), as well as surveying fulltime reading faculty and Access counselors at STLCC (Phase III) to ascertain their opinions of the Phase I and Phase II findings and to collect their opinions on a range of …

Microglial Activation By Amyloid-Beta, Geeta Subhash Paranjape

Dissertations

Paranjape, Geeta S.,Ph.D.,University of Missouri-Saint Louis, May 2012. Aβ(1-42) Protofibrils But Not Fibrils Activate Microglia. Major Professor: Michael R. Nichols. One of the hallmark features of the Alzheimer’s disease (AD) brain is the extracellular deposition of amyloid-β protein (Aβ) in both fibrillar (senile plaques) and diffuse forms. Significant proinflammatory markers including activated microglia and cytokines have been detected surrounding the plaques but are absent in diffuse areas suggesting that microglial activation is sensitive to Aβ structure. Since Aβ displays structural polymorphism in vitro, we sought to determine the relationship between Aβ aggregation state and microglial proinflammatory response. Size exclusion chromatography …

Perceptions Of Kentucky Secondary School Principals About Agricultural Education Programs: A Comparison Of Schools With And Without Agricultural Education Programs, Andy Joe Moore

Dissertations

Countless research suggests that secondary agricultural education programs could benefit all students regardless of school characteristics and geographic location, yet many secondary schools have yet to include agricultural education as part of their curricular offerings. In response, numerous studies have been conducted in recent years throughout the United States regarding how secondary agricultural education programs are perceived by school leaders. For the first time, this study sought to shed light on how secondary principals in Kentucky perceived agricultural education programs. Considered in this study, were how secondary principals with agricultural education in their schools perceived those programs differently than secondary …

First Year Baccalaureate Nursing Program Outcomes: Effects Of Prerequisite Courses And Preadmission Testing, Sonya House

Dissertations

Schools of Nursing are faced with the difficult task of selecting students for admission into nursing programs. This responsibility is challenging as the number of students applying to programs typically outweighs the number of students who can be admitted. As a result, faculty must identify methods for selecting students who have the greatest likelihood of being successful. As noted in the literature, attrition that occurs as the result of being academically underprepared is found in the beginning of nursing programs (Murray, Merriman, & Adamson, 2008). The central research question represents the purpose of the study: To what extent do prerequisite …

Evaluation Of Human Fecal Pollution In Mississippi Coastal And Creek Waters Using Library Independent Markers, Christopher John Flood

Dissertations

The objective of this study was to determine whether statistically valid correlations could be elucidated between standard indicator bacteria (enterococci and fecal coliforms) from coastal creek and marine samples and the presence of four library independent molecular markers that are human or sewage specific. Eight hundred and nineteen samples were collected between August 2007 and July 2010 to determine enterococcal and fecal coliform counts and the presence of genetic markers for sewage indicator organisms Methanobrevibacter smithii, human specific Bacteroides sp., Bacteroides thetaiotaomicron, and Fecalibacterium sp. During the course of this study environmental parameters were measured and statistically analyzed to determine …

A Model Exploration Of Teacher Efficacy, Attitudinal Beliefs, And Caring Behaviors Towards Latino Linguistically Diverse Students, Jennifer Keller Johnson

Dissertations

No abstract provided.

Will Implementing A Research Based Dese Approved Early Childhood Program Have An Effect On The School Readiness Of Prekindergarten Students, Stephanie Small

Dissertations

The purpose of this comparative study was to examine the connection between the implementation of a quality early childhood program and the kindergarten readiness of prekindergarten students as measured by the Developmental Indicators for Assessment of Learning-DIAL-3. The researcher analyzed historical data obtained from approximately 40 students in the Study Site School District in the prekindergarten programs at Woodbridge Elementary School for the 2008-2009 and 2009-2010 school years. The researcher developed two research questions: a) What impact does a MODESE approved, research-based early childhood program have on the kindergarten readiness of prekindergarten students in the Study-Site School District as measured …