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Dual Modality Optical Coherence Tomography : Technology Development And Biomedical Applications, Farzana Rahmat Zaki

Dissertations

Optical coherence tomography (OCT) is a cross-sectional imaging modality that is widely used in clinical ophthalmology and interventional cardiology. It is highly promising for in situ characterization of tumor tissues. OCT has high spatial resolution and high imaging speed to assist clinical decision making in real-time.

OCT can be used in both structural imaging and mechanical characterization. Malignant tumor tissue alters morphology. Additionally, structural OCT imaging has limited tissue differentiation capability because of the complex and noisy nature of the OCT signal. Moreover, the contrast of structural OCT signal derived from tissue’s light scattering properties has little chemical specificity. Hence, …

Speciation Of Gaseous Oxidized Mercury Molecules Relevant To Atmospheric And Combustion Environments, Francisco J. Guzman

Dissertations

Mercury is a pervasive and highly toxic environmental pollutant. Major anthropogenic sources of mercury emissions include artisanal gold mining, cement production, and combustion of coal. These sources release mostly gaseous elemental mercury (GEM), which upon entering the atmosphere can travel long distances before depositing to environmental waters and landforms. The deposition of GEM is relatively slow, but becomes greatly accelerated when GEM is converted to gaseous oxidized mercury (GOM) because the latter has significantly higher water solubility and lower volatility. Modeling GOM deposition requires the knowledge of its molecular identities, which are poorly known because ultra-trace (tens to hundreds part …

Interventions Of Waterjet Technology In Skin Incisions, Nadi Atalla

Dissertations

This research explores the use of waterjet (WJ) technology in performing skin incisions. The study defines the analytical relationships between the skin properties and the operating parameters of the WJ which include the skin thickness, its elastic modulus, the WJ pressure, the nozzle’s orifice diameter, its stand-off distance and the traverse speed of the WJ as well as the duration of applying the WJ pressure. An analytical model is developed to measure the depth incision of the skin, the water pressure and the water velocity, while using a WJ. Systemization and optimization models that determine the optimal operating parameters levels …

Statistical Machine Learning Methods For Mining Spatial And Temporal Data, Fei Tan

Dissertations

Spatial and temporal dependencies are ubiquitous properties of data in numerous domains. The popularity of spatial and temporal data mining has thus grown with the increasing prevalence of massive data. The presence of spatial and temporal attributes not only provides complementary useful perspectives, but also poses new challenges to the representation and integration into the learning procedure. In this dissertation, the involved spatial and temporal dependencies are explored with three genres: sample-wise, feature-wise, and target-wise. A family of novel methodologies is developed accordingly for the dependency representation in respective scenarios.

First, dependencies among discrete, continuous and repeated observations are studied …

Epitaxial Growth Of Iii-Nitride Nanostructures And Their Optoelectronic Applications, Moab Rajan Philip

Dissertations

Light-emitting diodes (LEDs) using III-nitride nanowire heterostructures have been intensively studied as promising candidates for future phosphor-free solid-state lighting and full-color displays. Compared to conventional GaN-based planar LEDs, III-nitride nanowire LEDs exhibit numerous advantages including greatly reduced dislocation densities, polarization fields, and quantum-confined Stark effect due to the effective lateral stress relaxation, promising high efficiency full-color LEDs. Beside these advantages, however, several factors have been identified as the limiting factors for further enhancing the nanowire LED quantum efficiency and light output power. Some of the most probable causes have been identified as due to the lack of carrier confinement in …

N8- Polynitrogen Stabilized On Carbon-Based Supports As Metal-Free Electrocatalyst For Oxygen Reduction Reaction In Fuel Cells, Zhenhua Yao

Dissertations

The sluggish oxygen reduction reaction (ORR) kinetics at the cathode is one of the key factors limiting the performance of polymer electrolyte membrane fuel cell (PEMFC). Platinum-based materials are the most widely studied catalysts for this ORR reaction while their large-scale practical application in fuel cells is hindered due to their scarcity and low stability. Therefore, highly active, low cost and robust non-Pt catalysts are being developed to overcome the drawbacks. Recently, a novel polynitrogen N8- (PN) stabilized on multiwall carbon nanotube (MWNT) was synthesized under ambient condition for the first time by our group and demonstrated high ORR activities. …

Surface-Enhanced Raman Detection Of Glucose On Several Novel Substrates For Biosensing Applications, Laila Saad Alqarni

Dissertations

The small normal Raman cross-section of glucose is considered to be a major challenge for its detection by Surface Enhanced Raman Spectroscopy (SERS) for medical applications. These applications include blood glucose level monitoring of diabetic patients and evaluation of patients with other medical conditions, since glucose is a marker for many human diseases. This dissertation focuses on Surface-Enhanced Raman Scattering primarily for the detection of glucose. Some experiments also are carried out for the detection of the corresponding enzyme glucose oxidase that is used in electrochemical glucose sensors and in biofuel cells. This project explores the possibility of utilizing Surface …

Workload Allocation In Mobile Edge Computing Empowered Internet Of Things, Qiang Fan

Dissertations

In the past few years, a tremendous number of smart devices and objects, such as smart phones, wearable devices, industrial and utility components, are equipped with sensors to sense the real-time physical information from the environment. Hence, Internet of Things (IoT) is introduced, where various smart devices are connected with each other via the internet and empowered with data analytics. Owing to the high volume and fast velocity of data streams generated by IoT devices, the cloud that can provision flexible and efficient computing resources is employed as a smart "brain" to process and store the big data generated from …

Fouling And Aging In Membrane Filtration : Hybrid Afm-Based Characterization, Modelling And Reactive Membrane Design, Wanyi Fu

Dissertations

Membrane filtration has been extensively used in water and wastewater treatment, desalination, dairy making, and biomass/water separation. However, membrane fouling, aging and insufficient removal efficiency for dissolved organic matters remain major challenges for wider industrial applications. In order to tackle these challenges, this doctoral dissertation investigates mechanisms of membrane fouling and development of antifouling membrane filtration technologies. Specifically, four major research areas are explored: (i) nanoscale physicochemical characterization of the chemically modified polymeric membranes; (ii) quantitative modelling between membrane properties and membrane fouling and defouling kinetics; (iii) development of quantitative structure-activity relationships for membranes that undergo thermal and chemical aging …

Engineered Excipients Via Dry Particle Coating, Liang Chen

Dissertations

Excipients with good flowability, bulk density as well as compaction properties are desired for use in tableting since they play important roles in formulation development and processing, including, handling, mixing, feeding and compaction. However, it is often difficult to manufacture excipients that simultaneously possess all three desirable properties, particularly if their size is fine. In addition, it is desirable that the excipients promote direct compression of poorly compactable fine cohesive drug powders at sufficiently high drug loading, and not just achieve the desired high functional properties in placebo formulations. This dissertation aims to developed engineered excipients towards this unmet industry …

Temporal And Functional Cortical Aspects Related To Mirror Visual Feedback During Target-Directed Movement In Healthy And Stroke Individuals, Maryam Rohafza

Dissertations

Stroke is the leading cause of disability in the United States (American Heart Association, American Stroke Association) affecting 800,000 individuals annually (i.e., one person every 45 seconds). Therapy for stroke often uses repetitive task practice, which is difficult to perform for patients due to impairment. Mirror visual feedback (MVF) based rehabilitation uses the effect of observing the mirror reflection of volitional movement of one limb, to activate visuomotor brain areas that process movement of the opposite limb. In persons with hemiplegia due to stroke, exercising the less affected limb while observing its reflection, perceived by them as the motion of …

Variables Affecting Quality Of Life And Adherence In Adults With Type 2 Diabetes, Michele L. Poradzisz

Dissertations

The purpose of this two-phase mixed methods study was to examine the influence of selected variables on quality of life (QOL) and adherence to diabetes regimen in a convenience sample of adults with Type 2 diabetes. Participants were all clients of the same American Diabetes Association-recognized diabetes center and had previously received comprehensive diabetes education.

Evolving An Ecological Way Of Thinking: Social Interactions And The Construction Of Environmentally Sustainable Behaviors In Adolescents During Expeditionary Learning, Jennifer Fruend

Dissertations

The people around us - as well as the methodical progression of education through content - often shape our relationship to the world. Currently, Earth is at a crossroads, which requires humans to act and live more sustainably with an intentional environmental ethos, whether for literal survival or for slowing Earth’s resource degradation. Situated within the models of ecological contributors such as Aldo Leopold, transformational experiences, particularly when processed with self-reflection, writing, and social interaction, can change behaviors and priorities in individuals. Additionally, by recognizing the place of social learning components in expeditionary, informal, or adventure-based education settings, the potential …

Phylogeographic Relationships Of Coereba Flaveola And Their Malaria Parasites, Meghann Humphries

Dissertations

This dissertation is broadly focused on elucidating how the geographic structure and demographic changes in host and parasite populations relate to one another, and how such interactions contribute to the generation and maintenance of biological diversity.

I begin by investigating the population structure of the Coereba flaveola (bananaquit) population within Puerto Rico, which is the apparent source of several expansions of the species into the Lesser Antilles. These findings indicate that both island and taxon effects influence the observed demographic changes. Because susceptibility to antagonists is related to both host species-specific characteristics and to geographical location, coevolutionary outcomes of these …

The Impact Of Instructional Technology On Lesson Effectiveness And Obstacles To Incorporating Technology Into Lesson Design As Perceived By Elementary School Teachers, Sarah Loring

Dissertations

Purpose. The purpose of this qualitative study was to identify and describe the impact of instructional technology on lesson effectiveness and obstacles to incorporating instructional technology into lesson design as perceived by elementary school teachers.

Methodology. A qualitative ethnographic method was used in this study. Triangulation was accomplished through the collection and analysis of direct interviews, and artifacts shared by educators and strengthened by information-rich data provided in direct observations.

Findings: Major finding of the study showed high student engagement with the use of technology, and unavailability of the internet/Chromebooks as a big obstacle to technology integration.

Conclusions: Based on …

Experienced Engagement In Appreciative Advising Of Adjunct Professors In Community College Education, Margaret Kenrick

Dissertations

Purpose: The purpose of this explanatory sequential mixed-methods study was to identify what Appreciative Advising strategies were used by adjunct professors to engage community-college students when participating in Appreciative Advising. The study was also designed to describe the experiences of the adjunct professors as they implemented the strategies of Appreciative Advising with students. In addition, it was the purpose of this study to describe the benefits and challenges adjunct professors experienced when participating in Appreciative Advising. Finally, this study sought to describe the impact to teaching practices experienced by adjunct professors who participated in Appreciative Advising.

Methodology: This study used …

An Investigation Of The Ability Of The Minnesota Early Childhood Screening Program To Predict Educational Achievement In Third Grade Children, Martha Dewey Bergren

Dissertations

The ecological model assumes school, community, family, and friends shape child outcomes. Minnesota mandates comprehensive Early Childhood Screening (ECS) for preschool children including vision and hearing, and cognitive, language, motor, growth and speech, with optional screening for health, behavior, and life stresses. Children meeting federal criteria for special education programs are recommended for interventions. Children with less serious health and/or behavior problems or who lack sufficient resources may also be at risk for academic difficulties. The purpose of this study was to investigate the ability of family, health, development, behavior, and stress data collected at Minnesota ECS to predict grade …

Outcome Evaluation Of An Interdisciplinary Care Model For Children With Cystic Fibrosis, Roberta P. Pawlak

Dissertations

Cystic Fibrosis (CF) is a life-limiting, autosomal recessive inherited disease that affects approximately 30,000 individuals in the United States. Health problems of children with CF tend to be complex, requiring specialty health services. Often children with CF are cared for in CF Care Centers, where an interdisciplinary care team addresses these needs. The Cystic Fibrosis Foundation (CFF) recommends specific Clinical Practice Guidelines be applied to all patients with CF. A major gap in the CF literature is evidence of guideline application results on health outcomes. The purpose of this study was to examine the influence of an interdisciplinary care model …

Comparison Of Two Methods For Measuring The Tangible Outcomes Of An Associate Degree Nursing Program, Denise Hooper Elliott

Dissertations

The purposes of this study were (a) to describe and measure the tangible outcomes of an Associate Degree Nursing (ADN) program for the graduate, the community, and cooperating clinical agencies; and (b) to propose a methodology that explicates the tangible outcomes of an ADN program. Using a descriptive design, tangible outcomes of one ADN program at a North Central Alabama community college were measured, collection methods were evaluated for effectiveness and efficiency, and the need for training of data collection staff was evaluated.

The Relationship Between Spouses' Strength Of Identification And Their Patterns Of Change In Perceived Body Space And Articulation Of Body Concept During And After Pregnancy, Jacqueline M. Fawcett

Dissertations

The family is a living open system characterized by pattern and organization. While the rate of change in pattern and organization varies throughout the life cycle of the family, few periods involve the rapid and extensive repatterning and reorganization present in pregnancy. Empirical evidence suggests that changes in body image occur during and after pregnancy in both wives and husbands. The study designed to test the hypotheses used a sample of fifty married couples who attended Lamaze preparation for childbirth classes.

A Quantitative Study Examining Project Lead The Way Gateway Program Outcomes In A Suburban School District, Patrick Joseph Bellinger

Dissertations

Within the confines of this study, the Researcher investigated Project Lead the Way (PLTW) Gateway program outcomes at a Midwest suburban school district. The study examined specific academic achievement outcomes and attitudes regarding STEAM courses and STEAM careers among students who completed at least one semester in a middle school PLTW Gateway program. The Researcher attempted to determine if there was a difference in student attitudes related to STEAM between students who enrolled in a PLTW Gateway course and students who never enrolled in PLTW Gateway, as determined in an online survey. The Researcher also attempted to determine if there …

A Quantitative Case Study On School Climate, Student Behavior, Student Achievement, And Classroom Facility Factors In An Urban Midwest High School, Shamonda Owens

Dissertations

This research was a quantitative case study on the possible relationship between school climate, student behavior, student achievement, and classroom facility factors in an urban Midwest high school. Specific variables included lighting, wall color, classroom temperature, school climate, student behavior, and student academic achievement. The researcher collected the following data: student behavior, number of out of school suspensions (OSS) students received in 2014 through 2017, End of Course data, 2014-2017, in the areas of Biology, American Government, English I, and English II. To measure school climate, the researcher used the district’s annual climate survey. School climate survey data measured student …

Modifying Inhibited Primer Performance Via Control Of Epoxy-Amine Matrix Structure And Composition, Steven Wand

Dissertations

This research represents an effort to deliver a new fundamental understanding of how polymer matrix characteristics influence corrosion protection of organic coatings, in particular the performance of corrosion inhibitor-containing primers. By modifying the structure and composition features of epoxy-amine matrices which commonly serves as the binder for protective coatings, the thermal/mechanical, adhesion, and transport properties which govern coating performance and inhibitor release were altered in such a way that directly influenced protection efficacy. This research is composed of three distinct approaches towards systematically varying thermoset network characteristics and observing the resulting impact on transport behaviors and corrosion prevention, with an …

“Polysoaps” Via Raft Copolymerization To Form Well-Defined Micelles For Water Remediation And Targeted Drug Delivery Applications, Phillip Pickett

Dissertations

Amphiphilic copolymers have become increasingly important for environmental and biological applications due to their behavioral characteristics in aqueous solution. For example, structurally-tailored statistical amphiphilic copolymers or “polysoaps” can self-assemble into micelles or other architectures in water at various concentrations. Polysoaps may be differentiated from small molecule surfactant micelles in their capability to self-assemble into unimolecular associates (unimolecular micelles) with no dependence on concentration. Such micelles offer enormous potential for dispersion of hydrophobic species in water at high dilution. Importantly, each polymer chain forms its own micelle and upon dilution, these micelles remain intact and capable of dispersing hydrocarbon material in …

Validation Of A Scale To Measure Phonological And Morphological Knowledge And Skill Of Speech-Language Pathologists And Elementary Teachers, Susan S. Perry

Dissertations

Phonological and morphological skills are crucial to the process of reading. Speech-language pathologists (SLPs) have received advanced trained in these basic foundations of language and could be an untapped resource in our school systems for teaching beginning reading skills. The purposes of this research were to examine SLPs’ and general education elementary (K-6) teachers’ attitudes toward SLPs taking part in reading instruction, to compare the differences in phonological and morphological knowledge and skill among SLPs and teachers, and to assess the performance of the Revised Basic Language Constructs Surveywhen administered to SLPs and teachers.

Results indicated that, although fewer …

Engineering Multifunctional And Morphologically Diverse Polymer Brush Surfaces, Cassandra M. Reese

Dissertations

The combination of surface-initiated polymerization (SIP) and post-polymerization (PPM) serves as a powerful approach to fabricate complex, multifunctional polymer films, which can be precisely tuned for desired surface engineering applications. Careful manipulation of PPM parameters such as reaction conditions, the tethered brush parameters, and the physical properties of the unbound post-modifier greatly influence the depth of penetration of the post-modifier and the polymer brush compositional heterogeneity. This dissertation focuses on engineering polymer brush surfaces with multifunctional chemistries and tunable morphologies by investigating the PPM parameters that dictate the distribution of post-modifiers on grafted polymer brush surfaces.

The first chapter of …

Fundamental Attribution Error: Perspectives Of Principal, Teacher, And Parent Influence On Student Growth, Sonja Rayner

Dissertations

The primary purpose of this study was to determine principals’, teachers’, and parents’ attributions of their own and the other groups’ relative influence on student academic outcomes measured by standardized tests. The secondary purpose was to determine whether and how fundamental attribution error and self-serving bias predicts or explains the responses of each group. Descriptive analyses were conducted to compare responses from these three constituent groups. Additionally, repeated measures MANOVA was conducted in order to explain the effect the moderator variable, school performance level, had on the strength of the relationship between the independent (school rating and group) and dependent …

Manipulation Of Noncovalent Interactions For The Synthesis And Use Of Natural Product Synthons, Alison P. Hart

Dissertations

Natural products are widely used in the pharmaceutical industry, in agriculture, and as specialty chemicals. Methodology development focuses on optimizing the key organic reactions to access these natural products while trying to limit the overall number of synthetic steps. Key bond forming strategies are sought to provide new ways to address carbon-carbon or carbon-heteroatom bonds. The advancement of new asymmetric reactions to generate enantiopure products from achiral starting materials is a vital area of research. The objectives addressed in this dissertation include: 1) the development of a general reductive conversion of esters to ethers with a broad substrate scope accessing …

The Cultural Adaptation Experiences Of Chinese Higher Education Students In The American Deep South: A Comparison Across Disciplines, Xiaonan Song

Dissertations

In the past decade, Chinese international students have been found as one of the largest international student groups at American institutions across the country. However, the American Deep South was not less frequently studied in the past. Due to the distinctiveness of the Deep South, the researcher conducted this qualitative research on Chinese international students studying in this historically and culturally distinctive region. Mississippi was chosen as a representative state of the Deep South in the current study. The researcher collected data from in-depth interviews from three publicly funded institutions in Mississippi. Besides reporting many common issues regarding to cultural …

A Mixed Method Study: Assessing Critical Thinking, Metacognition, And Motivation In A Flipped Classroom Instructional Model, Phyllis Brown

Dissertations

Technology has changed pedagogical methods in higher education. Educators are using technology more and integrating more active learning techniques. One pedagogical method, the flipped classroom, is suitable for integrating technology and active learning techniques. The pedagogical efficacy of the flipped classroom has not been determined despite being a potential solution for technology savvy millennial students. This mixed method study assessed critical thinking, metacognition, and motivation in higher education flipped classrooms in the United States. Human Anatomy and Physiology Society (HAPS) members teaching traditional and flipped format science courses were purposefully selected to participate in the study. A sample of 14 …