Digital Commons Network^™

Mechanical Characterization Of Animal Derived Starting Materials For Tissue Engineering, Bin Zhang

Dissertations

Animal derived starting materials are well established in the production of Tissue Engineered Medical Devices. Porcine specifically can be found in products ranging in application from hernia repair to breast reconstruction. Although this material has been largely accepted in the Tissue Engineering industry, little is known of its material properties and mechanical characteristics. A review of the scientific literature describes limited mechanical measures only on uncontrolled research grade material. The objective of this work is to mechanically characterize porcine starting material used in the medical device industry. Porcine skin is provided by Midwest Research Swine, LLC (MRS) an established supplier …

Identification Of Neurobiological Mechanisms Associated With Attention Deficits In Adults Post Traumatic Brain Injury, Ziyan Wu

Dissertations

Traumatic Brain Injury (TBI) is one of the major public health concerns with approximately 70 million new cases occurring worldwide per year. It is often caused by a forceful bump, blow, or jolt to the head, resulting in brain tissue damage and normal brain functions disruption. All grades of TBI, ranging from mild to severe, can cause wide-ranging and long-term effects on affected individuals, resulting in physical impairments, and neurocognitive consequences that permanently affect their abilities to perform daily activities. Attention deficits are the most common persisting neurocognitive consequences following TBI, which significantly contribute to poor academic and social functioning, …

Data Assimilation For Conductance-Based Neuronal Models, Matthew Moye

Dissertations

This dissertation illustrates the use of data assimilation algorithms to estimate unobserved variables and unknown parameters of conductance-based neuronal models. Modern data assimilation (DA) techniques are widely used in climate science and weather prediction, but have only recently begun to be applied in neuroscience. The two main classes of DA techniques are sequential methods and variational methods. Throughout this work, twin experiments, where the data is synthetically generated from output of the model, are used to validate use of these techniques for conductance-based models observing only the voltage trace. In Chapter 1, these techniques are described in detail and the …

Brasilidade In Built Form: Tracing National Identity In Modernist Architecture In Brazil, 1922–1968, Angela Starita

Dissertations

The conceptual framework of Brazilian national identity in built form changed drastically between the 1930s and the 1960s, from the Baroque of colonial-era Brazil to the improvised constructions of the poor. The advocates of these architectural imaginaries were not suggesting that these styles be copied. Instead, they used them as a type of hermeneutic for explicating how Modernism should be deployed in order for it to be authentically Brazilian. The transition from the colonial model to an aesthetics of poverty was a result of a confluence of factors. These included the country’s relatively new struggle to define itself away from …

Coding Against Stragglers In Distributed Computation Scenarios, Malihe Aliasgari

Dissertations

Data and analytics capabilities have made a leap forward in recent years. The volume of available data has grown exponentially. The huge amount of data needs to be transferred and stored with extremely high reliability. The concept of "coded computing", or a distributed computing paradigm that utilizes coding theory to smartly inject and leverage data/computation redundancy into distributed computing systems, mitigates the fundamental performance bottlenecks for running large-scale data analytics.

In this dissertation, a distributed computing framework, first for input files distributedly stored on the uplink of a cloud radio access network architecture, is studied. It focuses on that decoding …

Pegylated Block Copolymer For Cancer Imaging And Treatment, Sweety Singh

Dissertations

Gene theranostics have emerged as an important tool for the treatment of cancer as well as other diseases. Among the challenges in this field is the lack of effective vectors to chaperone plasmids into cells while the vector itself exhibits minimal toxicity. Herein, the synthesis, cellular uptake, and gene delivery using a biocompatible norbornene-based block copolymer is reported. This block copolymer, bearing polyethylene glycol moieties along with primary amines is functionalized with both a boron dipyrromethene (BODIPY) fluorophore for fluorescence tracking and a folic acid derivative for cancer cell targeting.

Stoichiometry control afforded residual unreacted amine functional groups available to …

Schwann Cells In Combination With Gag-Mimetic Scaffolds For Spinal Cord Repair, Sharareh Hashemi

Dissertations

Spinal cord injury (SCI) being a devastating neurological dysfunction can cause extensive irreversible neuronal loss and axonal damage. Fifty-four cases of spinal cord injury per million people occur annually in the United States. Due to the loss of glial cells and demyelination of axons, the neuronal function of surviving neurons is disrupted leading to permanent loss of sensory and motor functions. The glial scar formed by astrogliosis at the chronic stage protects undamaged tissues, but it is known to be a major barrier for axonal regeneration. The limited regeneration capacity of spinal cord makes it challenging to successfully treat the …

Effects Of A Primary Blast-Induced Traumatic Brain Injury On The Susceptibility To Behavioral And Neuronal Deficits On A Susequent Blunt Trauma, Aswati Aravind

Dissertations

Soldiers are often exposed to more than one traumatic brain injury (TBI) event over the course of their service. In recent years, more attention has been drawn to the increased risk of neurological deficits caused by the 'blast plus' polytrauma, which typically is a blast trauma combined with other forms of TBI. The objective of this dissertation is to investigate if exposure to a blast TBI predisposes the brain to increased neurological deficits when followed with a second blunt head trauma. The behavioral and neuronal deficits resulting from a blast plus injury involving a mild-moderate blast followed by a mild …

Comparing Teaching Strategies Utilized To Enhance Self-Confidence Among Novice Nursing Students, Ashley N. Carter

Dissertations

Faculty play a considerable role in positively impacting the development of a novice nursing student's self-confidence through contemporary, innovative, and meaningful teaching practices that are data-driven. Employing effective confidence-building teaching strategies early in the curriculum supports the development of confidence as a professional attribute and is critical to student success, patient safety, and patient comfort (Blum et al., 2010; Bulfone et al., 2016; Lundberg, 2008; White, 2009). This prospective, cross-sectional, quantitative, comparison pilot study compared the effectiveness of a role-play (RP) physical assessment simulation with a new teaching strategy, an individual high-fidelity physical assessment simulation (HFS), to determine the impact …

Health Literacy Preparation Of Bsn Students: A Basic Qualitative Study, Robin E. Squellati

Dissertations

Understanding the complexity of multiple health conditions, treatment options, and medications requires a high level of health literacy. Yet, 88% of Americans have some deficiency in health literacy. The nursing literature is lacking in best practices for teaching nursing students how to address health literacy concepts with their patients. Therefore, this basic qualitative study explored Bachelor's of Science in Nursing (BSN) students' educational preparation to integrate health literacy in patient education. The primary research questions asked, How do BSN students describe their preparation to integrate health literacy in patient education?

The Relation Between Patient Education And Picc Line Occlusion And Infection, Patricia L. Cameron

Dissertations

The purpose of this study was to test the feasibility of using an electronic tablet to supplement patient and caregiver education about PICC line maintenance and to compare the percentage of PICC line complications in the intervention group with national percentage rates for patients and caregivers.

Life Balance In Nurse Educators: A Mixed Methods Study, Joan M. Owens

Dissertations

The topic of nurse educator life balance is significant to the nurse educator community, which is facing a national nurse faculty shortage, challenges in producing enough new nurses, and a continuing shortage of nurses. This compromises patient safety and the quality of care. Major factors identified as contributing to the shortage of nurse educators are educator dissatisfaction with workload and work life balance. Life balance is described as an enjoyable array of daily activities that is meaningful and contributes to the individual's health. Professional quality of life is described as the quality one feels in relation to one's work as …

Physical Activity Improves Depressive Symptoms In Older Adults, Karen Lee Fahey

Dissertations

Engaging in physical activity can help older adults to take part in community activities, maintain relationships, and initiate new friendships, thus preventing loneliness and depression. The purpose of this quality improvement (QI) project was to evaluate whether participation in physical activity improved depressive symptoms in 15 older adults at a local senior center. Pender's health promotion model was used to determine nursing and behavioral science views on components that affect health behavior.

Consensus In Anesthesia Handoff Reporting, Robin L. Groves Anselm

Dissertations

Despite some improvement, no consensus exists to perfect quality in anesthesia handoff practice and policy. This quality improvement project was designed to assist a local anesthesia and perioperative workforce questioning the quality of its current handoff. Theories and models used to inform the project included the Inter-Professional Team Collaborative, Lewin's change theory, the continuous quality improvement theory, and the knowledge to action model. The communication assessment tool (CAT) functioned as a needs assessment yielding a gap in handoff practice of 25 participants. The CAT also served as the post project evaluation survey. The situation, background, assessment, and recommendation (SBAR) tool …

Effect Of Patient Handoff Methods On Nurse Self-Efficacy, Christopher Scott Guelbert

Dissertations

Patients experience multiple transitions in care between nursing providers (handoffs) during hospitalization. Handoffs are opportunities for communication errors to occur. Patient handoffs between the post-anesthesia care unit (PACU) to the nursing division is a frequent event within hospitals. Methods of handoff vary in practice from face-to-face, telephone, or written report. Nurses receiving patient handoff may experience varying degrees of self-efficacy levels in providing care to the newly acquired patient from the PACU. Self-efficacy levels can be measured utilizing the Nursing Care Self-Efficacy Scale (NCSES). Variances in nursing self-efficacy scores among the methods of face-to-face and telephone patient handoff were analyzed …

Syndemic Conditions And Medication Adherence In Older Hiv-Positive Men Who Have Sex With Men, Roland Zepf

Dissertations

For people living with HIV, lack of adherence to medication regimen is a significant problem with serious deleterious outcomes. Reasons for non-adherence are co-concurring psychosocial health conditions—also known as syndemic conditions—such as symptoms of depression, post-traumatic stress disorder (PTSD), past physical or sexual abuse, intimate partner violence (IPV), stimulant use, and binge drinking. Majority of all new HIV infections in the United States are among men who have sex with men (MSM). This dissertation reports on a secondary analysis of cross-sectional data from older MSM living with HIV receiving treatment at two outpatient HIV clinics in San Francisco.

How Does Standard Use Of A Rectal Acetaminophen/Intravenous (Iv) Opioid Combination Compare To Iv Opioid Alone In Improved Comfort Levels And Decreased Overall Opioid Use In Full-Term Infants Post Open Heart Repair?, Jacqueline M. Ochsenreither

Dissertations

Pediatric cardiothoracic surgical patients experience varying degrees of pain in the immediate post-operative period. Multiple analgesic modalities can be utilized to effectively manage pain in this specific patient population. Routinely, IV opioid only is prescribed post-operatively to manage acute pain needs in this select group of patients. However, standard use of rectal acetaminophen as an adjunct to IV opioid to improve comfort levels and decrease overall opioid use in the immediate post-operative period in this select population has not been examined. This retrospective, 18-month, quantitative study was conducted at a large urban children's teaching hospital incorporating electronic medical inpatient chart …

Veteran Specific Risk Factors For Delirium, Allison Perkins

Dissertations

Purpose/Aims: This study explored the relationships between military characteristics such as combat experience, mental health issues such as post-traumatic stress disorder (PTSD), traumatic brain injury (TBI), depression, anxiety and substance use disorder (SUD), physical comorbidities such as coronary artery disease (CAD), other risk factors, and delirium diagnosis among hospitalized veterans.

Background: Delirium is a common disorder experienced by 25% of all hospitalized adults 65 years and older. No published studies to date have examined whether combat, TBI and PTSD are associated with the incidence of delirium in the hospitalized veteran.

Methods: A retrospective cross-sectional cohort design with a sample size …

Interagency Collaboration In Local Partnership Agreements: A Qualitative Case Study Identifying And Describing The Perception Of Preparedness Of Transition Specialists Working In Workability I Projects, Barbara Boyd

Dissertations

Purpose: The purpose of this qualitative case study was to identify and describe the preparedness of transition specialists working in WorkAbility I (WAI) projects as perceived by transition specialists using Kohler’s Taxonomy for Collaborative Transition Programming. In addition, its purpose is to explore the perceptions of transition specialists regarding interagency collaboration in local partnership agreements (LPAs).

Methodology: This qualitative case study identified and described WAI transition specialists’ perception of transition programming and interagency collaboration. It employed the use of semi-structured interview questions consisting of open-ended questions. Using this methodology promoted the extraction of high quality information from the transition specialists. …

Examining The Effects Of A Peer-Mediated Social Skills Intervention On The Prosocial Behaviors Of Elementary Students With Emotional And Behavioral Disorders, Prabhjot Singh

Dissertations

Students with Emotional and Behavioral Disorders represent part of the population of students who receive special education services, and the social skill deficits that they present makes it so that they are less likely to pass their classes and more likely to drop out of school than their typical peers. The social skill deficits of these students often lead to a variety of negative factors including poor relationships and academic achievement. The purpose of this study was to examine the effects of a peer-mediated social skills intervention on fourth and fifth grade students in a public-school setting. The current study …

A Mixed Methods Study Identifying And Describing Factors To Promote Psychological Safety In Middle School Professional Learning Communities: Making The Bread Rise, William Cloo

Dissertations

Purpose: The purpose of this mixed methods explanatory study was to identify and describe factors of risk-taking behavior among Riverside County Professional Learning Community (PLC) middle school teachers. It elicited teacher perspectives of a psychologically safe PLC that promotes risk-taking. Additionally, it sought to identify factors that increase psychological safety in a PLC.

Methodology: This mixed methods study uses a sequential explanatory 2-step process to produce results. The quantitative-qualitative study started with a quantitative survey that collected and analyzed numerical data on levels of risk among the population. Qualitative interviews provided context and further explanation on the methods to foster …

Distress After Preterm Birth: A Discourse Analysis Of Parents' Accounts And Photographs, Ira Kantrowitz-Gordon

Dissertations

Preterm birth is a distressing experience for parents. This distress may continue into early childhood, with negative consequences for parents' mental health and child development. The purpose of this study was to take an in-depth look at how parents formed their accounts of premature birth, postpartum distress, and lives as parents and partners. Discourse analysis of semi-structured interviews and photo-elicitation assignments were used to analyze the parents' experiences in the context of the couple relationship.

La Maestra’S Circle Of Care: Studying The Impact Of An Integrated Service Model On The Health And Well-Being Of Vulnerable Populations, Zara Marselian

Dissertations

ABSTRACT

There is an urgent need to reform the health care delivery system in the United States, as recognized through current bipartisan efforts. Society’s vulnerable populations especially need health care reform as health care outcomes are the poorest among disadvantaged populations. Moreover, vulnerable populations are twice as likely to develop chronic diseases than the general population and they remain ill due to other contextual, societal factors affecting their ability to achieve health and well-being. This population is subjected to adverse life events that suggest a more comprehensive approach to health and well-being is called for.

The Circle of Care is …

The Effect Of Using Virtual Manipulatives On Students’ Ability To Mentally Compare Proper Fractions, William Wilson Mcneary Iii

Dissertations

This study proposes a method to analyze the effects of the use of virtual fraction models (circle/bar/number line) on students’ ability to mentally compare proper fractions. Since developing a sense of magnitude with both whole numbers and rational numbers is highly correlated with improved performance on standardized assessments and improved performance in later algebra classes, special attention is directed to the bar and number line as they are linear representations.

The study used an experimental pretest/posttest group design by randomly assigning subjects within class sections to a control group (physical fraction circles) and treatment groups with seven different methods of …

Moral Development And Public Health Nursing, Margaret Avila

Dissertations

Public health nurses (PHNs) have the opportunity and professional obligation to be at the forefront of the fight to eliminate health disparities based on the practice principle of social justice. The overall purpose of this descriptive study was to explore the stage of the moral development in a convenience sample of practicing public health nurses (PHNs) and the differences in moral development stage across selected demographic variables (age, gender, race/ethnicity, level of entry into professional nursing, highest level of education, years practicing as an RN, years practicing in a public health department, self-identified political views, primary language, and region of …

The Relationships Between Patients' Perceptions Of Nurse Caring Behaviors, Nurses' Perceptions Of Nurse Caring Behaviors And Patient Satisfaction In The Emergency Department, Theresa Bucco

Dissertations

Approximately 100 million people seek care in Emergency Departments yearly, which can be overwhelming for many Emergency Department (ED) nurses. Thus, caring for these patients and meeting their needs is challenging for ED nurses. It is the patients' perceptions of the first caring encounters in the ED that can have a significant impact on patient satisfaction.

The purpose of the study was to examine the relationships between patients' perceptions of nurse caring behaviors, nurses' perceptions of nurse caring behaviors, and patient satisfaction in the ED.

The Experience Of Viewing Self In The Mirror After A Mastectomy, Wyona M. Freysteinson

Dissertations

The purpose of this study was to talk with women who have had a mastectomy in order to discern the experience of viewing self in a mirror post-operatively. More specifically, the study sought to describe the experience from both a structural and a phenomenological perspective. The question guiding the study was: What is the experience of viewing self in the mirror after a mastectomy? Twelve women, who had a mastectomy 3-12 months prior to participation in the study, discussed their experiences of viewing self in mirror in audio-taped conversational interviews. A structural analysis was performed on each transcript, followed by …

The Biopsychosocial Model Of Metabolic Syndrome Among U.S. Adults, Jennifer L. Saylor

Dissertations

The Metabolic Syndrome (MetS) is a cluster of medical disorders (obesity, hypertension, dyslipidemia, and insulin/resistance/glucose intolerance) that characteristically occur together in individuals. The prevalence of MetS continues to increase in the U.S. and increases the risk of type 2 diabetes, cardiovascular disease (CVD), and mortality. Little research uses a theoretical model to identify direct or indirect contributions to MetS and predictors to MetS. Identifying the factors that influence MetS in a national sample is necessary to understand targets for intervention to prevent the MetS and its sequelae.

This study tested a hypothesized conceptual model of the biopsychosocial factors associated with …

Using A Collaborative Center For Integrative Reviews And Evidence Summaries To Narrow The Education-Practice-Research Gap, Cecelia Lorayne Crawford

Dissertations

The overarching purpose of this dissertation project was to design a collaborative center for integrative reviews and evidence summaries (CCIRES) to advance the state of the art and science of nursing knowledge and narrow the education-practice-research gap. The CCIRES program was created as a web-based platform embedded in the Kaiser Permanente Southern California infrastructure. The specific purpose of this project was to implement CCIRES via that infrastructure, and evaluate the implementation, structures, processes, and usability of CCIRES.

The Utilization And Effectiveness Of The Hesi E (Square) Exit Exam As A Graduation Requirement Toward Increasing Nclex-Rn® Pass Rates In Baccalaureate Nursing Programs, Debra Henline Sullivan

Dissertations

The purpose of the study was threefold. The first purpose compared the NCLEX-RN® first-time pass rates of BSN students in nursing programs that use the HESI E2 exit exam with other computerized exit exams, and those using no exit exam. NCLEX-RN® first-time pass rates for students taking HESI E2 did not show a statistically significant increase compared to students that took no exit exam. A second purpose, compared NCLEX-RN® first-time pass rates of BSN students in nursing programs utilizing the E2 that require a minimum benchmark score as a graduation requirement with those BSN students that use HESI E2 but …