Digital Commons Network^™

Reducing Pediatric Morbidity Through Development Of A Clinical Practice Guideline, Deanna Kroh

Dissertations

Peripheral intravenous therapy is a commonly utilized treatment modality for the care of acutely ill pediatric patients. Two risk factors include infiltration and extravasation injuries. These injuries, peripheral intravenous infiltration or extravasation injuries (PIVIEs), can vary in their clinical manifestations from minor discomfort to harm as severe as loss of limb or disfigurement. Clinicians caring for patients at risk of developing PIVIEs need to be able to act quickly to reduce potential morbidity. The purpose of this project was to create a clinical practice guideline (CPG) that would guide staff intervention if a PIVIE occurs, with the ultimate goal of …

The Impact Of Music Education On Middle School Students’ Attendance Rates And Academic Achievement On Math And English Language Arts, Irene Wang Shi

Dissertations

In recent years, students’ standardized test scores have become one of the major measurements for students’ learning. However, music as a non-tested subject is often viewed as a lesser valued subject compared to core subjects. The purpose of this study was to investigate the impact music programs have on student academic achievement and attendance rate. The data was collected from one middle school of a large school district located in the northeast of Missouri. The study population includes sixth, seventh, and eighth-grade students who enrolled in the 2017-2018, 2018-2019, and 2020-2021 school years. The population was divided into students who …

Evaluating Mindfulness On Loneliness In An Older Adult Population, Jessica Tieskoetter

Dissertations

Problem: Loneliness is a widespread public health concern and has negatively impacted mortality and health outcomes among older adults. This quality improvement project’s purpose was to evaluate mindfulness on loneliness and quality of life among adults aged 65 years and older, participating in a weekly befriending socialization program.

Methods: A descriptive cohort design was utilized to assess loneliness pre-and post-implementation of a mindfulness telephone line over three months. A convenience sample of 22 older adults enrolled in a befriending socialization program was used. The Iowa Model of Evidence-Based Practice framework was applied to guide the implementation of a practice change …

When St. Louis School Nature Leaders And Environmental Partners Work Together Nature-Based Learning Inspires Joy And Curiosity In K-2 Students, Julie Frisch, Melissa Politte

Dissertations

This study focused on what values teachers saw in nature-based learning, what outcomes they saw for their students, and what factors have enabled them to do nature-based learning. This explanatory sequential mixed-methods study looked at nature-based learning in St. Louis elementary schools with kindergarten through second-grade students.

We used purposive sampling to choose six schools to examine further through case studies. We then conducted interviews with 8 teachers on qualities of nature-based learning captured in 12 words.

We identified five themes from our interviews and observations: Every School Needs a Nature Champion, Community Bridges in Nature-Based Learning, There is Magic …

Standardizing Discharge Practices For Pediatric Urology Outpatient Procedures: A Quality Improvement Project, Megan Bush

Dissertations

Background: Standard discharge instructions of verbal and written methods are only understood by about 45-50% of caregivers. Video discharge instructions (VDIs) in addition to standard methods of verbal and written instructions can be very effective for caregiver comprehension (CC), retaining discharge education information and improving patient outcomes. Problem: In an outpatient surgery department in a Midwestern Children’s hospital, 100% of the discharge instructions for pediatric urology outpatient procedures are different than the instructions given to caregivers by the surgeon. Methods: The study utilizes a descriptive evaluation of change in how discharge instructions were written and provided. Interventions …

Untold Perspectives: The Impact Of The Closure Of A Health Institution In A Black Community In North St. Louis County, Patricia Zahn, Kiley Bednar, Andrea Jackson-Jennings, Erica L. Henderson

Dissertations

Based on the literature of social determinants of health, health equity, and anchor institutions, it is evident that hospitals have a role to play in ensuring the health of their community. However, our understanding of the impact of hospital closures is limited, especially when it comes to Black communities. The purpose of this study is to examine the relationship of the closure of the Normandy Osteopathic Hospital to the social determinants of health—specifically access to care and economic stability as it relates to income and wealth generation—for a Black community in one near-North suburb of St. Louis. Ten individuals with …

No One Can Whistle A Symphony: Analyzing Growth In Proficiency For English Learners In Coteaching, Debra Ann Cole

Dissertations

K-12 ELs in the U.S. are increasing in number and diversity (Park, et al., 2018), requiring schools to establish and grow language instruction education programs (LIEPs) that facilitate language acquisition for a wide range of learners, while also providing equitable opportunities to learn. The study used a quantitative, pretest-posttest, research design to address gaps in the literature noted by Takanishi & Menestrel (2017), regarding which LIEPs are most effective for various EL subgroups, and to explore the effects of Coteaching for ELs (COTEL) on growth in proficiency. Data from 723 ELs in two Midwestern districts was disaggregated three ways to …

We Eat, We Live, We Repeat: Reimagining Food Heritage Through Foodways And Sustainable Food Practices, Caitlin L. Crain, Amy L. Roznos, Britt L. Tate Beaugard, Darius L. Williams

Dissertations

The purpose of this co-authored, mixed methods descriptive research study was to examine how the intersection of foodways and sustainable food practices helps define the food heritages of St. Louis area residents. While prior research examines these concepts separately, and even shows connections with other factors such as health and discrimination, none look at all of these concepts together—a gap this research fills. To that end, this dissertation describes the intersection of cultural foodways and connection to sustainability in seeking a definition of food heritage and a path towards sustainable food heritage for St. Louis residents. Purposeful sampling using the …

Effects Of Forest Restoration On The Recovery Of Dead Wood, Associated Arthropods, And Insect-Mediated Wood Decomposition, Estefania Fernandez Barrancos

Dissertations

Dead wood represents 8% of terrestrial carbon stocks and is an important source of habitat and food for decomposer and non-decomposer arthropods. However, anthropogenic disturbance reduces the amount of dead wood, putting at risk the presence of a habitat that is essential for many arthropods and other organisms that rely on it for food and shelter. Forest restoration aims to assist the recovery of ecosystems that have been damaged or destroyed and could be a means to recover both dead wood and its associated arthropod communities. This doctoral dissertation lies at the intersection of climate change, biodiversity loss and ecological …

Military Instructors' Perspectives Of Integrating Instructional Multimedia Into Military Classrooms, Keontra Campbell

Dissertations

The United States Army has made efforts to meet the demand for digital technology. There is a continued need to train Soldiers with integrated multimedia instruction products to ensure soldiers are combat-ready. The purpose of this study was to investigate military instructors' lived experiences and perspectives on interactive multimedia instructional (IMI) product integrations' influence on students learning experiences and knowledge transfer and to understand the challenges instructors face, the strategies, needs, barriers, and the resources they use when integrating IMI products at a U.S. Army School of Excellence. The study uses a qualitative research design using a phenomenological approach. The …

Characterizing Endogenous Dicer Products To Unravel Novel Rnai Biogenesis Pathways, Jacob Oche Peter

Dissertations

ABSTRACT

RNA interference (RNAi) is a pervasive gene regulatory mechanism in eukaryotes based on the action of multiple classes of small RNA (sRNA). Exploiting RNAi pathways in non-model systems have great potential for creating potent RNAi technologies. Here, we accessed RNAi-mediated control of gene expression in the two-spotted spider mite, Tetranychus urticae (T. urticae) using engineered dsRNA designed to modulate the host RNAi pathway and increase RNAi efficacy. Analysis of Dicer (Dcr) generated fragments revealed how exogenous RNAs access the host RNAi pathway in this animal, opening avenues for designing RNAi technology for their control. Further, some organisms …

Investigating Pedestrian Distraction By Phone At Intersection Crossings, Safety Implications And Potential Treatments, Lusanni Mercedes Acosta Rodriguez

Dissertations

Road user distraction is a major safety concern. The issue is not only for drivers, but also for vulnerable road users such as pedestrians. Every year people are involved in potential and real crashes due to being distracted while walking/crossing streets. Although there are several ways by which pedestrians are distracted, phone use while crossing streets is among the riskier and growing behaviors. Crossing an intersection, especially those with heavy traffic, requires full attention from the individual. Inattentiveness to traffic while on a phone call, texting, web-surfing, listening to music before crossing a street can lead to a fatal crash. …

Oncolytic Tanapoxvirus Variants Expressing Mil-2 And Mccl-2 Regress Human Pancreatic Cancer Xenografts In Immunocompromised And Immunocompetent Cann.Cg-Foxn1Nu/Crl Nude Mice, Scott David Haller

Dissertations

Pancreatic ductal adenocarcinoma (PDAC) is the fifth leading cause of cancer-related death in Western countries. The incidence of PDAC has increased over the last 40 years and is projected to be the second leading cause of cancer death by 2030. Despite aggressive treatment regimens, prognosis for patients diagnosed with PDAC is very poor; PDAC has the lowest 5-year survival rate for any form of cancer in the United States (US). PDAC cases are rarely detected in early stage when surgical resection can be performed and few, approximately 20%, are suitable for surgical resection which remains the only curative treatment when …

From Young To Old: The Effects Of Sedentary-Aging And Exercise Interventions On Structural Plasticity Of Lumbar Motor Neurons, Nmj, And Glial Cell Line-Derived Neurotrophic Factor Expression, Alberto Felipe Cintron-Colon

Dissertations

Neuromuscular weakness has been associated with age progression. A possible reason is a disconnection between muscle and neuron, causing components from both the central and peripheral nervous systems to deteriorate. Exercise, however, has beneficial effects for both muscle and nervous tissue, inducing neuroprotection. Neurotrophic factors are powerful regulators of neuronal maintenance and synaptic strength. Glial cell line-derived neurotrophic factor (GDNF) is a neurotrophic factor that has been shown to be a potent survival factor for somatic motor neurons that innervate skeletal muscle.

This study aims to evaluate changes in structural plasticity of motor neurons in the lumbar spinal cord and …

German Imperialism And Applied Orientalism: German Encounters With The Ottoman Empire, 1850-1918, Matthew David Penix

Dissertations

Edward Said’s influential treatise on culture and imperialism, Orientalism, specifically called out German scholars of the Islamic “Orient” as being different. The lack of a formal German empire in Muslim lands seemed to preclude a culture of Orientalism. This dissertation examines the lived experience of Germans who traveled and worked in the Ottoman Empire from 1850-1918. As German interests sought their “place in the sun” during the decades before 1914, the Ottoman Empire became a major field of business investment, military-to-military contact, and missionary endeavor for Germans acting at the behest of both state and private interests. Their experiences formed …

The Language-Dream Relationship In Multilinguals, Brittany Dishaun Burkes

Dissertations

According to the United States Census Bureau, the United States alone is host to around 350 languages. When it comes to investigating languages in dreams by multilinguals, some studies have focused heavily on only two languages—Spanish and English. The purpose of this study was to add to the understanding of how language use relates to the dream content of multilinguals. This study recruited the assistance of nine polylingual individuals. The participants were instructed to record their dreams in the languages in which they occurred for 2 weeks. After 2 weeks, the participants translated their dreams into English in order for …

The Relationship Between Adolescent Exposure To Community Violence, Depression, And Resilience, Nieves A. Esquivel

Dissertations

The present study experimentally investigated the development of depressive symptoms in adolescents who have been exposed to community violence. Participants (N=334) were asked to take a survey of 81 questions addressing one’s exposure to neighborhood violence, resilience, and depressive symptoms. Participants exposed to community violence reported more depressive symptoms in every category except Ineffectiveness. Participants who were exposed to community violence also reported higher resilience levels. Given the results, more research is needed to understand the specific factors of resilience that may prevent adolescents exposed to community violence from developing depressive symptoms.

Factors Influencing Community Responses To Hoarding: Evaluating Operational Culture Of Hoarding Task Forces, Stigma, And Successful Outcomes, Leslie Gail

Dissertations

Hoarding is generally recognized as a pervasive need to acquire and retain items past the point of maintaining safe living spaces. Ushered into popular culture through television shows highlighting conflict, awareness of hoarding has increased. Experts report this condition affects 2-5% of the adult population, but this figure does not include children, family, neighbors, and community members (Buscher et al., 2013; Minor and Youth Children of Hoarding Parents, 2021). A unique feature of hoarding is the myriad of ways it is discovered.” People who hoard may keep conditions a secret due to a lack of awareness, concerns about forced remediation, …

They Don'y Expect You To Know Much: Black African International Students Encountering And Countering The Afropessimistic Attitude Within Academic Spaces, Margaret Sergon

Dissertations

Black African international students in the United States are vulnerable to increased microaggressions because of their minority statuses. In addition to being Black and speaking with non-native accents, African students must contend with Afropessimism which in this study refers to the Western world’s negative perception of Africa. The study is a mixed methods study that seeks to understand how the Afropessimistic attitude impacts the way Black African international students are perceived and interacted with, within the academic spaces. The findings indicate that African international students consistently encounter the Afropessimistic attitude, and it impacts their academic engagement. The findings also suggest …

Prevalence Of Lost Time Injuries And Fatalities Among Construction Workers In Al Ain, United Arab Emirates (Uae), Ghuwaya Humaid Alnuaimi

Dissertations

Migrants account for more than 80% of the total population of the United Arab Emirates (UAE). Few population-based data were available about the burden of lost time injuries (LTIs) and fatalities among migrant workers employed in the construction industry. The proposed study aimed to estimate the prevalence of LTIs and associated factors, and fatalities among construction workers in Al Ain, of Abu Dhabi Emirate in the UAE. A cross-sectional study design was used to estimate the prevalence of LTIs resulting in one or more than a day of sick leave in a random sample (n=1,626) of male construction workers in …

An Evaluation Of The Effects Of Sub-Chronic Ketamine Exposure On Rodent Memory As Assessed By The Odor Span Task In Female Rats, Angela Marie Thomas

Dissertations

Though numerous studies have been undertaken to explore the mechanisms of action of antidepressant medications, little is known about the origins of the disorders they treat. Recently, the therapeutic value of ketamine as a treatment for depression was recognized by the Food and Drug Administration. Historically, ketamine has been used in the laboratory setting to induce ‘schizophrenia-like’ symptomology in humans and animals to allow for further study of those symptoms in a controlled environment; a correlation between ketamine use and deficits in memory and cognitive function has been suggested. This study evaluated the impact of sub-chronic sub-anesthetic ketamine on performance …

Analysis Of The Zebrafish Olfactory System Using Immunohistochemistry And Enhanced Techniques Of Desorption Electrospray Ionization Mass Spectrometry (Desi-Ms), Tara Lynn Maser

Dissertations

Desorption electrospray ionization (DESI-MS) is an ambient ionization technique where the sample is analyzed directly from a surface with very minimal sample preparation under ambient conditions and follows ESI-like ionization mechanisms. DESI-MS has proven powerful in analyzing or imaging lipids and other small molecules directly from biological samples and even allows for subsequent histological staining and analyses. However, DESI-MS is less widely used for protein analysis due to a lack of sensitivity and the complex diversity of proteins in biological samples.

A major goal of this research has been to obtain new neurobiological knowledge by combining histology and mass spectrometry …

Understanding The Interfacial Processes Of Reactive Nanobubbles Toward Agricultural Applications, Xiaonan Shi

Dissertations

There is a growing interest in nanobubble (NB) technology because of its diverse applications (e.g., detergent-free cleaning, water aeration, ultra-sound imaging and intracellular drug delivery, and mineral processing). NBs have a higher efficiency of mass transfer compared to bulk scale bubbles due to the high specific surface areas. The high specific surface also facilitates physical adsorption and chemical reactions in the gas liquid interface. Furthermore, the collapse of NBs creates shock waves and the formation of hydroxyl radicals (OH).

However, it remains elusive why or how NBs are stabilized in water and particularly, the states of internal pressures of NBs …

Assessing Structural And Functional Brain Alterations And Work-Related Fatigue In Non-Hyposmic And Hyposmic Covid-19 Survivors, Rakibul Hafiz

Dissertations

In the year 2019, life began to change at the advent of a global pandemic caused by the novel coronavirus. Mask mandates and mass vaccinations have mitigated the effects significantly, yet cases keep rising with new variants, especially, in densely populated countries, like India. Recent neuroimaging evidence shows the virus can attack the central nervous system (CNS). However, exactly which brain regions undergo structural and functional changes remain largely unknown. Many patients experience 'loss of/reduced sense of smell' (i.e., hyposmic) and an alarming number of survivors develop persistent symptoms ('long-COVID') for several months after initial infection. Fatigue is the most …

Repeated Low-Level Blast Induces Chronic Neuroinflammation And Neurobehavioral Changes In Rat Models, Arun Reddy Ravula

Dissertations

Blast-induced neurotrauma (bTBI) is a signature medical concern for military personnel when they are exposed to explosions in active combat zones. However, soldiers as well as law enforcement personnel are also repeatedly exposed to low-level blasts during training sessions with heavy weaponries as part of combat readiness. Service personnel who sustain brain injuries from repeated low-level blasts (rLLBs) do not display overt pathological symptoms immediately but rather develop cognitive impairments, attention deficits, anxiety, and sleep disturbances over time. An improved rat model of rLLB was developed in this thesis by applying controlled low-level blast pressures (10 psi) repeated five times …

Design Of Self-Assembled Peptides For Wound Healing, Ka-Kyung Kim

Dissertations

According to the CDC, 15% of diabetic patients develop diabetic foot ulcers (DFU) and approximately 170,000 patients undergo non-traumatic amputation annually. DFU is a major complication of diabetes caused by non-healing full-thickness wounds through the dermis. The current treatments include blood sugar control, frequent debridement, offloading, moist wound care, infection treatment, and amputation. To achieve wound closure of DFU, appropriate wound care and antibiotic therapy are essential. Topical regimens include hydrocolloids, alginates, foam, silver-impregnated dressings, and hydrogels. Wound healing is a complex and dynamic interplay between the immune system, keratinocytes, and dermal cells (in case of cutaneous wound). Angiogenesis has …

An Exploratory Study On How Math Stories Engage Young Learners In Mathematical Sense-Making, Maria Gigi Carunungan

Dissertations

This is an exploratory study of how pedagogy in the form of math stories, shapes young learners’ perceptions, motivations, and sense-making of math concepts. The research is presented in an exploratory documentary, with audio-video data collected through the iPhone. The pilot test of story-driven math learning solutions was conducted by two teachers with eight first grade children from diverse backgrounds in an afterschool program. This study also includes interviews of the teachers, educational leaders and specialists in primary school curricula, children’s literature, and math education. The results of the pilot validated the efficacy of story-driven math learning solutions for mathematical …

Remifentanil Patient Controlled Analgesia Use In Laboring Women: A Feasibility And Acceptability Study, Joshua Carr

Dissertations

Background/Purpose: Interest in remifentanil patient controlled analgesia (RPCA) as a treatment for labor pain has increased due to its unique pharmacodynamics and effectiveness on pain control among parturients. Despite its promise, RPCA remains infrequently used in the US. The purpose of this study was to 1) examine the implementation and acceptability of a new RPCA protocol in the labor and delivery ward of a mid-sized hospital, and 2) identify the attitudes and beliefs of healthcare workers in a real-world clinical setting.

Theoretical/Conceptual Framework: The holistic nature of Comfort Theory can account for the proposed mechanisms contributing to the …

A Study Of The Challenges Faced By Students Who Identify As Refugees Who Have Experienced Interrupted Education And Trauma, Merdin Mohammed

Dissertations

Every year, more than 65 million people are displaced worldwide. These refugees, asylum seekers, and internally displaced people flee conflict, poverty, environmental degradation, and other conditions forcing them from their homes. In 2020, the number of individuals internally displaced reached 82.4 million; of this total, 26.4 million were refugees. In 2021, of the 11,411 refugees resettled in the United States, 8.6% resettled in California. When refugee students come to San Diego, the majority resettle in the neighborhoods of City Heights and El Cajon. These refugee children have lived on the road or in refugee camps, faced consistent interruptions to a …

Effectiveness Of Fall Prevention Multimedia Program On Patient Awareness, Self-Efficacy, And Engagement, Perlita C. Cerilo

Dissertations

Hospitalized adults are at high risk of falls during their acute episode of care making fall prevention programs a critical element of care. Patient self-efficacy and engagement in fall-prevention activities are important aspects of fall-prevention programs. Education may play an important role in increasing self-efficacy and the likelihood of engagement; however, a gap in evidence explores the effect of patient education on self-efficacy and engagement among hospitalized older adults in preventing falls. This quasi-experimental study examined the effect of a multimedia program on hospitalized adults' levels of fall risk awareness, self-efficacy, and engagement in fall prevention. Sixty hospitalized adults in …