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Longitudinal Evaluation Of Vitamin D Concentrations In Relation To The Onset Of Type 2 Diabetes In American Adults: A Secondary Data Analysis, Kathryn Michelle Schurr

Dissertations

Background: Prior research has suggested that low levels of Vitamin D may have negative effects on various biological functions, including Type 2 diabetes. The relationship between Vitamin D and the risk of Type 2 Diabetes has not yet been fully investigated. The objective of this research is to examine patients’ laboratory test data longitudinally to determine how vitamin D and other covariates of interest affect Type 2 diabetes status over time.

Methods: This study used retrospective data review from Quest Diagnostics from January 1, 2010, through December 31, 2022. Patients included in the study were required to have consecutive test …

Systematics, Biogeography, And Floral Trait Evolution Of The Plant Genus, Medinilla (Melastomataceae), John Peter Quakenbush

Dissertations

Medinilla is a large paleotropical genus in the plant family Melastomataceae with a long history of systematic uncertainty. The first objective of this research is to test the monophyly of Medinilla. A species tree is estimated using 599 nuclear gene trees, and 87 concatenated chloroplast genes are used to estimate the plastid phylogeny. Sampling includes 272 Medinilla and outgroups. Pachycentria and Plethiandra are resolved within Medinilla. Other fleshy-fruitedgenera long associated with Medinilla (i.e., Catanthera, Heteroblemma, Kendrickia) belong to other clades. With this new evolutionary framework, an infrageneric classification system is proposed for Medinilla consisting of …

Beneficial Effects Of Exercise On Glial Cell Line-Derived Neurotrophic Factor Content And Endplate Morphology In Skeletal Muscle Of Aging Male And Female Rats, Juliana M. Vangyseghem

Dissertations

Premenopausal women display lower incidence and severity of neurological disease compared to men of the same age, yet these populations are often treated similarly. A decline in neuromuscular function is associated with aging, which may be partially explained by a decline in neurotrophic factor expression with age. A possible way to maintain neuroprotection would be to regulate the production and release of a target-derived neurotrophic factor, such as glial cell line-derived neurotrophic factor (GDNF). GDNF has been shown to be the most potent survival factor for motor neurons and GDNF content of skeletal muscle has been shown to increase with …

Identity And Alterity In A Comedy Series From Santa Cruz, Bolivia, During The Presidency Of Evo Morales, Anita L. Zandstra,

Dissertations

This dissertation explores the construction of social identity and social difference in and through Neo/Los Mismos, a Bolivian comedy series produced during the presidency of Evo Morales (2006-2019), the country’s first president to claim an Indigenous identity. These years were characterized by profound divisions between the Bolivian highlands, home to Morales’s base of support, and the opposition based in the lowlands department of Santa Cruz. This qualitative study takes an interdisciplinary approach to social identity and social difference during the Morales era, drawing on concepts from linguistic anthropology, literary criticism, and humor studies, and tracing connections between Neo/Los Mismos and …

Experiential-Based Research Depicting Humanistic Survival After Violent Victimization & Traumatization Exploring Human Resilience, Spirituality, Meditation & Expressive Writing, Sabrina Harris

Dissertations

Unattended trauma-induced stressors resulting from incidents of violent victimization can escalate into mental health challenges, including trauma-related and substance-abuse disorders, which most often co-occur in a debilitating manner. Therefore, it is essential to conduct ongoing exploratory research on cognitive-based approaches (e.g., spirituality), psychological adaptations (e.g., human resilience), and trauma-informed approaches (e.g., meditation, expressive writing), which serve to reduce or offset the adverse impact of trauma.

Twelve women who experienced victimization and traumatization but did not seek professional mental-health intervention were interviewed; six had been abused as children and eight as adults. Some did not contact or follow through with reports …

Developmental Programming Of Normal Versus Metabolically Altered Pancreas In Rat: Effect Of Gestational Diabetes, Sanabil Ali Ahmed

Dissertations

Diabetes Mellitus (DM) is a chronic condition characterised by pancreatic β-cell dysfunction and consistently elevated blood glucose levels (hyperglycaemia), either due to the inability of the body to produce any or adequate amounts of insulin or the inability of the body to effectively utilise the produced insulin (i.e., insulin resistance). DM can be classified into 3 main types: Type 1 DM (T1DM), Type 2 DM (T2DM), and Gestational Diabetes Mellitus (GDM). GDM is defined as “hyperglycaemia that is first diagnosed during pregnancy with glucose levels below those considered diagnostic of overt diabetes outside of pregnancy”.

The mature pancreas is a …

Transforming Fermentation Residues From Date Fruit Pomace For The Synthesis Of Bioadsorbent Material In An Integrated Biorefinery Framework, Sabeera Haris

Dissertations

In the pursuit of enhanced waste management solutions, this comprehensive research delves into the untapped potential of Date Fruit Pomace (DFP), an abundant byproduct from the date syrup industry that is currently underutilized, leading to environmental concerns. The study emphasizes the need for proper waste management and valorization strategies to mitigate the environmental impact of DFP and promote sustainability within the date processing industry. The initial phase involves characterizing DFP from Emirati varieties, highlighting its compositional and functional properties. The analysis reveals that DFP is rich in total dietary fiber (45.5%), residual sugars (35.3%), protein (10.6%), ash (4.1%), and fat …

Say Her Name: A Phenomenological Study On Black Women’S Experiences With Fearful Encounters With The Police, Marilyn Shantey Buford

Dissertations

Police violence is a historical, systemic issue that continues to plague the Black community to this day. Research discussing the systemic oppression of police violence on Black people has seen an increase over the past decade. However, little has been discussed on the effects of police violence on Black people’s health and wellness, particularly their mental health. The research that exists surrounding police violence and mental health is largely concentrated on the experiences of Black men. Little is known about how Black women personally experience police violence or how these experiences impact their mental, emotional, and physical health. Not exploring …

Uncovering The Lifeworlds Of College Students Who Are Food Insecure: An Interpretive Phenomenological Inquiry, Amber L. Kolesar

Dissertations

Food insecurity (FI) is a concern for many college students, and contributes to significant physical, mental, and academic stressors. Experts have described the need for qualitative research. A better understanding of the experience of FI among college students may help to inform future research and interventions to support students on their educational journey. This study sought to interpret the lived experience of FI, with specific focus on the sociocultural context in which students experience FI, and its' contributing factors. Incorporating the philosophical perspective of Merleau-Ponty, the researcher utilized interpretive phenomenological analysis to uncover the life-worlds of food-insecure college students.

Qualitative Study: Brain Breaks In Primary School Classroom, Mandeep Biring

Dissertations

Purpose: The purpose of this qualitative phenomenological study was to identify and describe the brain break strategies used by exemplary primary grade teachers to support student learning for each of the three different types of brain breaks (breathing breaks, movement breaks, and mental breaks). A further purpose of this study was to identify primary teachers’ perceptions of which brain break strategies are most effective to support student learning.

Methodology: A phenomenological research design was used for this study. A qualitative method was used to collect data which included conducting semistructured interviews and observations with participants to gain information related to …

Reproductive Biology Of The Jellyfish Outbreak Along The Uae Coastal Waters, Amrutha Aravind

Dissertations

Jellyfish are a ubiquitous occurrence in the world’s oceans. During the past decades, dramatic spatial increases and temporal shifts in jellyfish distributions have been reported around the world. The United Arab Emirates (UAE) coastal area also has experienced several blooms along with severe adverse impacts on its economic facilities. Few studies have been conducted within the Arabian Gulf and the Sea of Oman, to identify the blooming species and the environmental parameters that favor such breakouts. The present study aimed to identify the jellyfish species found along the coastal area of UAE and trying to link their occurrence with seasonal …

Shepherds Leading The Flocks: A Qualitative Phenomenological Study Of Church Leaders Managing Church Membership During The Covid-19 Pandemic, Rbetrice Phillips

Dissertations

Purpose: The purpose of this phenomenological study was to identify and describe experiences of church leaders adapting the Scarneo (2019) intrapersonal and interpersonal socioecological influences while managing membership during the COVID-19 Pandemic.

Methodology: This study used a qualitative phenomenological approach with a socioecological justification with open-ended interview questions investigating the lived experiences of the participants. This study aimed to gather data from sample size 10 church leaders in Los Angeles County, California plus a snowball sampling of referred church leaders who managed during COVID-19. In this study, the collection of narratives through semi-structured interviews provided the data which was analyzed …

Nursing Leadership Characteristics: Effect On Nursing Job Satisfaction And Retention Of Baby Boomer And Generation X Nurses, Sandra L. Swearingen

Dissertations

The purpose of this research is to determine the degree to which nursing staffs that have a positive experience with nursing leadership are more likely to demonstrate job satisfaction. The different values and norms of the generational cohorts result in each cohort perceiving leadership characteristics differently. In addition, factors such as length of exposure to nursing leadership characteristics, location of work, shift of work, clinical versus non-clinical positions and the presence or absence of Servant-Leadership, all have the potential to impact nursing satisfaction. Nursing satisfaction or dissatisfaction impacts nursing retention, further modifying nursing leadership practices.

A Design Thinking Mixed Methods Study On Learned Empathy Through Multicultural Education, Samanantha Webb

Dissertations

The dissertation in practice focused on addressing the issue of inadequate diversity, equity, and inclusion (DEI) competencies among teachers in a Title I school. The problem of practice emerged within the context of an increasingly diverse educational landscape, necessitating educators to possess robust DEI skills. The proposed solution was a professional development (PD) program, crafted using a design thinking approach, which included an asynchronous learning module supplemented by a book study. The comprehensive PD program was aimed at enhancing the teachers' understanding and application of DEI principles, making the prototype relevant to the demands of multicultural education in today’s diverse …

Evaluating The Susceptibility Of The Lew.1wr1 Rat To Glucose Intolerance, Insulin Resistance, And Masld : Is Fat10 The Key?, Quiana Claudette Wilkerson Vidal

Dissertations

Obesity is an epidemic that affects over 40% of adults in America. Obesity can be divided into metabolically healthy and metabolically unhealthy obesity, with the latter being characterized by symptoms closely associated with metabolic syndrome, type 2 diabetes, and metabolic dysfunction-associated steatotic liver disease (MASLD). What causes the transition from metabolically healthy to metabolically unhealthy obesity is not fully known. Further, it is unclear how this transition correlates with the onset of co-morbid conditions. We propose that Ubiquitin D (FAT10) may play a role in transitioning into a metabolically unhealthy state in response to obesity. This dissertation evaluated two main …

Mitigation Of Inflammation In Early Post-Traumatic Osteoarthritis Through Low-Intensity Ultrasound, Shahid Khan

Dissertations

Post-traumatic osteoarthritis (PTOA), a subset of OA caused by direct injury or repetitive microtrauma, results in a robust release of inflammatory mediators. If inadequately controlled, this pro-inflammatory phase leads to early tissue damage. The biomedical burden of PTOA is significant and inadequately addressed due to difficulties in identifying the disease onset, slow progression, and incomplete understanding of its etiology and pathogenesis. However, PTOA's distinct initiating events allow for early intervention. This thesis investigates whether fibronectin fragments (FnFs) can induce an early inflammatory response in a triple cellular in vitro model of early PTOA and whether continuous low-intensity ultrasound (cLIUS) can …

Assembly And Analysis Of Space Biofilm-Forming Bacterial Model Organisms Towards The Treatment Of Water System Biofilms, Yo-Ann VéLez Justiniano

Dissertations

Space exploration imposes unique challenges on the human body and engineered systems alike. One such challenge is the control of microbial life, specifically biofilms, within the water processor assembly of the International Space Station (ISS). This investigation aimed to determine the feasibility of using an innovative bioremediation approach to mitigate biofilm growth in the water processor assembly. This approach entails the dissemination of a desired anti-biofilm gene across the microbial population of the water processor assembly through horizontal gene transfer via conjugation. To ascertain the viability of this method, the research was divided into two primary focuses. The first part …

Exploring Manifestations Of Pluriform Love In The Leadership Of Christian Early Childhood Communities: A Phenomenological Study 2019-2024 In New Zealand, Sharon Kaye Judge

Dissertations

Problem

This study responds to the need to explore and/or propose models of leadership for Christian early childhood education and care (ECEC) settings in New Zealand (NZ). While previous studies identify love and care as a priority there is a need to define and prioritize Biblical understandings of love that may align with the principles of the national ECE framework. The study represents an alternative narrative to the neo-liberal influences which dominate areas of ECEC leadership through the marketization and standardization of children’s services nationally and globally.

Purpose of Study

Many factors contribute to the purpose of this study which …

Cbct Perceptions Of Radiology Leaders In The Midwest Dental Schools: A Qualitative Study, Tenzin Dadul

Dissertations

Problem

The integration of Cone Beam Computed Tomography (CBCT) in dental education is hindered by a lack of formal training among radiology leaders, insufficient institutional support, and financial constraints. Despite the proven efficacy of CBCT in enhancing diagnostic accuracy and treatment planning, its adoption in pre-doctoral curricula remains limited. This gap in education poses significant challenges for dental graduates, who are increasingly expected to utilize advanced imaging technologies in clinical practice.

Purpose of Study

This qualitative study aimed to explore the perceptions of radiology leaders in Midwest dental schools regarding the integration of CBCT education into pre-doctoral curricula. The objectives …

Employees' Perception Of The Management Of The Covid-19 Crisis At Najran University, Saudi Arabia, Noora Nasser Alsuhaibani

Dissertations

Problem

During the COVID-19 crisis, particularly in the context of Saudi education, the ability to physically attend schools and colleges was greatly hindered due to the widespread transmission of the virus and the resulting obstacles. The issues necessitated the use of crisis management strategies. Some Saudi universities are capable of implementing an organized plan both before to and during crisis management, whereas others lack this competence. This is a substantial problem. Several universities in Saudi Arabia effectively managed the COVID-19 epidemic, whereas others did not. Furthermore, prior studies on crisis management indicate that administrators exhibit diverse responses. By participating in …

The Relationship Between Secondary Ela Teacher Pedagogical Practices, Student Self-Regulated Learning And Digital Self-Efficacy In A Blended Learning Environment, Melissa K. Miller

Dissertations

In the era of emerging technologies in the 21st Century classroom, secondary English Language Arts (ELA) students may exhibit complications in navigating literacy in blended learning environments. The purpose of this research study focused on addressing a gap in the current literature in these specific areas to investigate the relationship between ELA teachers’ pedagogical practices and elements of secondary students’ learning motivation for ELA. Specifically, this study explored secondary ELA students’ perception of teachers’ classroom practices, self-regulated learning, and digital self-efficacy. The overarching research question in this study examined: What relationship exists between (a) the pedagogical practices of secondary ELA …

Developing Geopolymer-Based Adsorptive Materials For Nutrient Removal From Agricultural Runoff And Drainage, Gabrielle Jacquelle Savoir

Dissertations

With the rise of population placing strain on food supplies and the failure of current prevention strategies to mitigate effects of agricultural pollution, research is needed to develop new technologies for the removal and recovery of nutrients from agricultural runoff and drainage. Geopolymer, an alkali-silicate material polymerized within an acidic or alkaline medium, is promising as an adsorptive substrate due to its multifaceted customizability, cost effectiveness, and adsorptive properties. Hence, the objective of this research was to develop porous metakaolin (MK) geopolymer based adsorptive materials with high affinities for phosphate and ammonium/ammonia to act as nutrient control within agricultural runoff …

Context-Aware Machine Learning For Low-Burden Brain-Computer Interfaces, T. Warren De Wit

Dissertations

We are interested in the utility that artificially intelligent mobile systems such as drones offer to personnel in fast-paced, high-stakes situations such as disaster relief that demand real-time situational awareness. Ideally, these assistive systems place no additional cognitive or physical burden on their user; rather, they should respond to the user's intent with minimal physical or cognitive impact. Artificial intelligence (AI) and machine learning (ML) are already widely applied in both brain-computer interfaces (BCI) and drone navigation. We propose leveraging the robust computer-vision based AI that exists on modern drones to use objects as waypoints and fly a reconnaissance drone …

The Role Of Semaphorins In Response To Injury In C. Elegans Neurons, Maria Belen Harreguy Alfonso

Dissertations

When neural tissue is injured by trauma, delicate neuronal processes such as axons and dendrites are prone to lesion damage and often disconnect. The molecular, cellular, and circuit mechanisms that underlie the regrowth and reconnection of these processes and the recovery of behavior are major challenges in the fields of neuroscience, regeneration, and resilience. At the molecular and cellular levels, signaling pathways that mediate neuronal growth cone guidance during development can play a role in neuronal regeneration and recovery from injury. One family of signaling proteins involved in this process comprises the highly conserved semaphorins and their receptors, the plexins. …

Novel Photobase Generators For Photoinduced Polymerization And Ph Regulation, Shupei Yu

Dissertations

Photochemistry encompasses the investigation of chemical processes instigated by light absorption. As important branches of photochemistry, photosensitive and optical materials have attracted extensive research interests in both academia and industry. Photosensitive and optical materials are composed of polymers / small molecules with photo-responsive properties. These materials not only can absorb light in the desired energy spectrum, but also exhibit chemical / physical reactions, which can be applied to different fields such as photoredox, photo-heat, phototherapy, solar cells, diodes, etc. Among them, photobase generators (PBGs) are a series of photosensitive compounds, which absorb the incident light, then release the basic species …

Assessing The Feasibility And Mechanism Of Destructive Removal Of Per- And Polyfluoroalkyl Substances (Pfas) From Water, Kaushik Vinaykumar Londhe

Dissertations

One of the most pertinent challenges faced by the drinking water community is the widespread contamination of per- and polyfluoroalkyl substances (PFAS). These anthropogenic chemicals have been ubiquitously used in everyday products such as carpets, stain repellents, dyes, shampoos, non-stick cookware as well as in aqueous firefighting foams. PFAS are linked with adverse health effects in humans such as thyroid disease, obesity, immunological and reproductive disorders and linked to cancer in adults and low birth weight and developmental defects in infants.

Conventional water treatment technologies have proven to be largely ineffective in PFAS remediation, due to their extreme stability and …

Distributed Intelligence: Exploring Federated Paradigms Across Computing And Networking On The Edge, Yang Deng

Dissertations

Computer Graphics (CG) revolves around virtual content creation using computational methods, spanning applications from games to visual effects. Typically, the creation of CG content is led by expert practitioners who guide computational algorithms towards satisfactory results. Thus, creating CG content often requires manual iterations encompassing algorithm design, parameter tuning, and aesthetic feedback. This work investigates how to leverage crowd-sourcing to streamline such creation processes, focusing on animation and simulation. In animation, a novel crowd-sourcing framework is proposed for combat animation, enabling users to analyze motion similarities, and retrieve matching motions using novel crowd-sourced motion features. Such features enable quantifying previously …

Development Of Novel Protein Digestion And Quantitation Methods For Mass Spectrometic Analysis, Yongling Ai

Dissertations

Proteins are the workhorses of biology, playing multifaceted roles in maintaining cellular function, signaling, and response to environmental cues. Understanding their abundance and dynamics is pivotal for unraveling the complexities of biological processes, which underpins the foundations of molecular and cellular biology. Accurate measurement of protein quantities provides insights into cellular homeostasis, facilitates the discovery of biomarkers, and sheds light on the molecular mechanisms of diseases, bridging the gap between the molecular intricacies of proteins and their functional consequences in health and disease. The evolution of protein quantitation methodologies, from classical colorimetric assays to sophisticated mass spectrometry-based approaches, has expanded …

Establishing A Novel Lipid-Polyamine Metabolic Connection To Virus Replication, Yazmin Edith Cruz Pulido

Dissertations

Polyamines are small positively charged alkylamines found in all living cells. These ubiquitous molecules have been found to play a variety of roles ranging from stabilizing nucleic acids (DNA and RNA) to cellular proliferation. Studies have also identified roles for polyamines in viral packaging and viral enzyme function. However, the role of polyamines on cellular components and their effect on viral replication is less known. In our efforts to identify the lipid-polyamine metabolic connection to virus replication we utilized a human hepatocyte cell line in which polyamines were depleted via pharmacological or genetic approaches and studied the effects on lipid …

Relationship Between School-Wide Positive Behavior Interventions And Supports, Student Achievement, And Teacher Efficacy In High Poverty Rural Alabama Elementary Schools, William Combs

Dissertations

The purpose of this research study is to determine if relationships exist between the level of School-wide Positive Behavior Interventions and Supports implementation, student academic achievement, and teacher self-efficacy in high-poverty rural Alabama elementary schools. The research encompassed a comprehensive analysis of existing literature, incorporating historical and policy-related context, theoretical underpinnings, relevant studies, and expert viewpoints. Additionally, the research involved the gathering and examination of data, presentation of findings, establishment of conclusions, and suggestions for prospective research directions. The primary objective of this study is to investigate potential correlations between the extent of SWPBIS (School-Wide Positive Behavior Interventions and Supports) …