Digital Commons Network^™

Estrogen Influences On The Developing Rat Hippocampus Through Interactions With The Brain Derived Neurotrophic Factor And P160 Coactivator Proteins, Derek Tyler Solum

Dissertations

In addition to their primary role in the maintenance and regulation of reproductive capacity, ovarian steroid hormones acting through specific nuclear receptors influence more general neurobiological functions, such as perceptual-spatial skills and learning and memory. Estrogens act to alter certain aspects of cognitive performance and pathology such as epileptic seizure activity and Alzheimer’s disease. Furthermore, ovarian steroids act during development to alter the neuronal cytoarchitecture and synaptic connectivity. These early influences of steroids on the brain are essentially permanent and in part determine the steroid responsiveness of the adult brain. The mechanism and sites of action for the effects of …

The Fatherhood Of God: An Exegetical Study From The Hebrew Scriptures, David Russell Tasker

Dissertations

The purpose of this dissertation is to develop a theology of the fatherhood of God from the Hebrew Scriptures. Although many studies have explored the topic from the perspective of other disciplines, the actual theology of God's fatherhood, as revealed in the Hebrew Scriptures, has been neglected until now. This has resulted in the dichotomization between the concept of God as presented in the so-called Old and New Testaments.

Because of the tendency to explain God through the lenses of Greek and Roman mythology, chapter 1 surveys ANE thought, showing that the fatherhood of god concept goes back a lot …

Teachings From Cree Elders: A Grounded Theory Study Of Indigenous Leadership, Leona Makokis Edd

Dissertations

For the past two hundred and fifty years, the relationship between First Nations and Euro-Canadians, has shifted from an equal partnership to one of colonized and colonizer. Despite this history, First Nations people have shown resiliency, continuing to honor beliefs, values, and traditions. Constrained by Euro-Canadian government Indian Affairs polices, First Nations have not progressed economically or politically, but have been caught in the trap of administering their own poverty. The First Nations people are dying a slow death; thus, it is critical to examine their current reality, acknowledging that history does not begin with the arrival of the Europeans, …

Intergenerational Transmission Of Values Through Adages In An Ecuadorian Family, Norma Albán-Lowry

Dissertations

Problem. This study explored the function of adages in intergenerational value transmission in an Ecuadorian family. Drawing on the richness of Hispanic culture, the study documents a method used by parents and grandparents to pass on their wisdom to younger generations.

The transmission of values to younger generations has always been of special interest to parents, teachers, and religious educators. While the role of the family in the transmission of values has been researched, the use of adages, long practiced as a traditional parenting method in Ecuadorian families, had not been studied.

Method. The ethnographic method, as proposed …

The Evolving Face Of God As Creator: Early Ninteenth-Century Traditionalist And Accommodationist Theological Responses In British Religious Thought To Paleonatural Evil In The Fossil Record, Thane Hutcherson Ury

Dissertations

The Topic

From the early Reformation through the early 1800s, Gen 1-11 was consensually understood as providing a perspicacious, historical account of how God brought the world into being. Tenets of belief included six literal 24-hour days of creation and a catastrophic global Flood, and most often the conviction that Gen 1:31 implies that no evil of any type existed prior to the Fall. New geological interpretations in the early nineteenth century, however, pointed toward an earth history that seemed anything but very good, instead suggesting a harsh concatenation of deep-time prelapsarian pain, struggle, destruction of the weak, predation, diseases, …

Environment, Cultures, And Social Change On The Great Plains: A History Of Crow Creek Tribal School, Robert W. Galler Jr.

Dissertations

This study explores the socio-cultural history of a school for Native American students on the Crow Creek Sioux Reservation in central South Dakota. The case study places the school's history (1886-present) within the context of the historic interaction between environment, cultures, and social change on the Great Plains.

This work focuses on a Catholic school and the multi-dimensional students and staff who constitute its story. These individuals acted neither as perpetually passive students nor simplistically sinister administrators. Instead, this dissertation broadly explores the challenging nature of intercultural relations that led to the founding of the school and how tribal/Catholic interactions …

An Account Of Novice Phylogenetic Tree Construction From The Problem-Solving Research Tradition, Terrance E. Brisbin

Dissertations

Both the content and strategic knowledge used in phylogenetic tree construction are described to account for novice performance. A review of the literature is used to place this research with respect to studies in: problem solving studies (both expert, and novice), the history and practice of evolutionary systematics, and the teaching of evolution. The computer-based problem-solving environment is discussed along with model problems used for the research.

Each of the five research problems consists of an encoded matrix containing phylogenetic data organized by taxa and characters. Twelve participants (high school students) volunteered to solve the research problems, on their own …

An Examination Of Voir Dire From An Interactionist Perspective, Peter R. Stevenson

Dissertations

Trial attorneys, historically, have used both scientific and unscientific selection techniques to empanel a jury, and these methods continue to be used in contemporary courtrooms. The ability of these techniques to pick a 'good” jury has been shown to have limited utility. This ineffectiveness may be due, in part, to a false assumption about the passivity of prospective jurors during questioning. An interactionist perspective sees individuals as much more active in that they control the information given out. Most potential jurors offer genuine presentations of self during jury selection in that they truthfully respond to the questions posed by courtroom …

A Preliminary Investigation Of The Acceptability And Effectiveness Of Computer-Based Adjunctive Parent Training For Child Noncompliance, Dwayne M. Munneke

Dissertations

Noncompliance with parent requests is a commonly reported behavior problem for clinic-based child referrals. Parent skills training has been empirically demonstrated as an effective treatment for helping parents increase positive child behaviors and decrease negative behaviors. Unfortunately, many therapists and agencies are unable to implement parent-training programs due to limited therapist training, limited economic resources, or long waiting lists.

Adjunctive, computer-based, treatment programs have become increasingly popular in both research and clinical settings for facilitating psychological assessment and intervention. This project involved the development and preliminary investigation of the effectiveness and acceptability of a computer-based program designed to supplement therapist-delivered …

Whatever Shines: Poems, Kathleen Mcgookey

Dissertations

The poems in my manuscript can be divided into two groups: poems in verse and prose poems. The majority are prose poems. Though I did not set out to write in the prose poem form, I’ve become more and more attracted to it, eventually seeking what Baudelaire sought when he wrote the poems in Le Spleen de Paris, a poetic prose "musical without rhythm or rhyme, supple enough and shocking enough to adapt itself to lyrical movements of the soul, undulations of the reverie, sudden leaps of conscience." Charles Simic believes prose poems contain a tension between the lyric impulse …

Affective Responses To Television Newscasts: Have You Heard The News?, Jessica Purtan Harrell

Dissertations

This study examined the impact o f television news viewing on affective responses in viewers. Participants watched a 10-minute newscast that contained only negative, only positive, or both negative and positive news stories at either 8:00 a.m. or 6:00 p.m. Negative news viewers showed elevations in anxiety and negative affect, while positive news viewers showed decreases in anxiety and negative affect. Watching a combined newscast resulted in no mood changes. Affective changes caused by watching the news were not maintained 3 hours after viewing, and morning versus evening viewing had no impact on mood responses to that news. While news …

Intermodal Transit System Coordination With Dynamic Vehicle Dispatching, Md. Shoaib Chowdhury

Dissertations

In most urban areas where transit demand is spread widely, passengers may be served by an intermodal transit system, consisting of a rail transit line (or a bus rapid transit route) and a numbers of feeder routes connecting at different transfer stations. In such a system, passengers may need one or more transfers to complete their journey. Therefore, scheduling vehicles operating in the system with special attention to reduce transfer time can contribute significantly service quality improvements. In this study two models, one for coordination of a general intermodal. transit system and another for dynamic dispatching of vehicles on coordinated …

Genetically Evolved Dynamic Control For Quadruped Walking, Giorgio Grasso

Dissertations

The aim of this dissertation is to show that dynamic control of quadruped locomotion is achievable through the use of genetically evolved central pattern generators. This strategy is tested both in simulation and on a walking robot. The design of the walker has been chosen to be statically unstable, so that during motion less than three supporting feet may be in contact with the ground.

The control strategy adopted is capable of propelling the artificial walker at a forward locomotion speed of ~1.5 Km/h on rugged terrain and provides for stability of motion. The learning of walking, based on simulated …

Endotoxin Removal From Protein Solutions By Immobilized Metal Ion Affinity Chromatography, Yun Kang

Dissertations

In the biotechnology/pharmaceutical industry, the removal of endotoxins from final protein product has always been a challenge. A novel method for endotoxin removal from protein solutions, immobilized metal (ion) affinity chromatography (IMAC) has been developed in this study. Fe³⁺ was charged to a chelating gel that contains iminodiacetic acid (IDA). The IDA- Fe³⁺ IMAC column was exploited to remove endotoxin from protein solutions. This method involves the adsorption of the endotoxin on IMAC column. More than 99% endotoxin is removed and protein yield is higher than 90%. IDA-Fe³⁺ IMAC has proved to be an economical and efficient …

Investigation Of The Baroreflex Of The Rat : Steady State And Dynamic Features, Xiaorui Tang

Dissertations

The baroreflex is one of the most important feedback systems in the body to maintain blood pressure variation within the homeostatic range. In this dissertation, the important features of the carotid and aortic baroreflexes have been extensively investigated on ventilated, central nervous system intact, neuromuscular blocked (NMB) rats using different control system and signal processing tools. Studies have demonstrated that sinoaortic denervation (SAD) caused substantial increases in the blood pressure variability. Comparing the pre- and post-SAD blood pressure spectra, there was a significant increase of power in the very low frequency region (0.00195 -0.2 Hz), and a significant decrease of …

Applications Of Agent Architectures To Decision Support In Distributed Simulation And Training Systems, Plamen V. Petrov

Dissertations

This work develops the approach and presents the results of a new model for applying intelligent agents to complex distributed interactive simulation for command and control. In the framework of tactical command, control communications, computers and intelligence (C₄I), software agents provide a novel approach for efficient decision support and distributed interactive mission training. An agent-based architecture for decision support is designed, implemented and is applied in a distributed interactive simulation to significantly enhance the command and control training during simulated exercises. The architecture is based on monitoring, evaluation, and advice agents, which cooperate to provide alternatives to the …

Simulation And Modeling Of Magnetically-Assisted Impaction Coating (Maic) Process For Dry Particle Coating, Bodhisattwa Chaudhuri

Dissertations

The objective of proposed research is to model, and understand the processes happening at multiple length and time scales in magnetically assisted impaction coating process. The smallest length scale is of the order of the molecular size and is important because during collisions the molecules rearrange themselves to form a semi-permanent bond between the core and secondary particles, which is studied by using the results of direct numerical integration of the governing Newton's equations. The effect of parameters such as size, orientation and relative velocity of particles on the collision mechanics is quantified. The largest length scale which is the …

Identification And Classification Of Coryneform Bacteria Isolated From Bovine Mammary Glands, Jeffrey L. Watts

Dissertations

Coryneform bacteria are frequently isolated from bovine mastitis and these infections are associated with economic losses. Corynehacterium bovis, a lipid requiring species, has been the most frequently isolated coryneform from the milk of infected bovine mammary glands. However, the taxonomic status of this organism is uncertain. In the current study, a polyphasic approach was used to identify coryneform bacteria isolated from bovine mastitis and determ ine the phylogenetic relationships among the identified species. A total of 212 coryneform bacteria isolated from bovine mastitis was obtained from mastitis reference laboratories in the United States and Canada. Presumptive identification based upon …

Molecular And Biological Characterization Of A Tanapox Virus Tnf-Binding Protein And The Complete Nucleotide Sequence Of The Psti-J Genomic Fragment, Mini Paulose-Murphy

Dissertations

Most of the poxvirus encoded virulence factors have been identified as proteins that are secreted from infected host cells. Some of these secretory proteins impede host immune defenses. We have previously demonstrated that tanapox virus (TPV) infected cells secrete a 38 kDa glycopeptide that binds to human (h) interferon-γ, h-interleukin (IL)-2, and hIL-5. We now show an additional activity in the supernatant from TPV infected cells that down-regulates the expression of tumor necrosis factor-a (TNF-α) induced cell adhesion molecule gene expression. This activity was not detected in mock infected cells. Enzyme linked immunosorbent assays (ELISA) on primary human endothelial cells, …

In-Line Measurement Of Solibility Of Physical Blowing Agents In Thermoplastic Melts As Related To Extrusion Foaming, Qiang Zhang

Dissertations

A novel in-line method for measuring physical blowing agent solubility in thermoplastic melts in extrusion foaming equipment has been developed in this study. This method uses video microscopy in connection with a foaming extruder (single or twin-screw) to generate solubility data by observing the onset of gas bubble formation/dissolution. This method offers a number of advantages over the existing conventional methods. It can be easily used to obtain solubility data for many foamable thermoplastic-physical blowing agent systems at high pressure and temperature near actual foaming conditions. Data generated using this method could be directly used to characterize and control a …

Finite Fraction Method For Tracking Desinfection By-Product Precursors In Water Treatment, Doanh Van

Dissertations

Dissolved Organic Matter (DOM) has been the subject of recent regulatory activities and agenda. Among them are the Infonnation Collection Rule (ICR), the Disinfectants/Disinfection By-Product Rule (D/DBPR) and the Interim Enhanced Surface Water Treatment Rule (ESWTR). Both the latter two have provisions to limit the formation of disinfection by-products (DBP) by controlling reactivity and removal of DOM or both. Brief regulatory review of these rules was given.

Although the topic of DBP formation potential and DBP precursor removal have been studied by many researchers since Rooks (1974), the efficacy of methods that have been developed to date has been handicapped …

Tell Hesban And Vicinity In The Iron Age, Paul J. Ray

Dissertations

Problem. Tell Hesban is a major archaeological ruin in central Transjordan. It was excavated from 1968-76 by Andrews University. However, almost 25 years after the termination of this endeavor, a final report dealing with the Iron Age remains has not yet appeared. Although relatively little remains from the Iron Age, which is the earliest period represented on the tell, an understanding of what is left is nevertheless important for comprehending the role the site played in the region at this time.

Method. A historical research design has been used in this study. The excavated architectural and soil/debris layers were analyzed …

Differential Perceptions Of English Teachers About The Teaching Of Literature In Seventh-Day Adventist Secondary Schools In Selected Regions Of The Caribbean, Shirley Ann Mcgarrell

Dissertations

Problem. Literature, as a subject in the English curriculum, is not taught in all Seventh-day Adventist (SDA) secondary schools in the Caribbean. This research attempts to investigate and document the reasons why this subject is not taught as part of the English curriculum in some schools and yet is taught in other schools. Literature, as a course of study, addresses philosophical, moral, ethical, and spiritual questions, and often teachers are not the central controllers in determining whether this subject should be taught in church-operated secondary schools. The literature teacher’s role could be pivotal in this situation, but only if …

The Issue Of Antitrinitarianism In The Fifteenth-Century Novgorod-Moscow Movement: Analysis And Evaluation, Oleg Zhigankov

Dissertations

This study attempts to examine the trinitarian beliefs of the fifteenth-century Novgorod-Moscow movement, analyzing both their own writings and the polemical writings of those who considered their teaching antitrinitarian.

The main objective of the present research is to contribute to the restoration of the authentic theological identity of this movement. Chapter 1 defines the problem, which has already been raised by some nineteenth-century scholars who have pointed out that the allegedly antitrinitarian character of the Subbotniks' movement must be open for further discussion. It also shows that no systematic research on Subbotniks' theology has ever been produced.

The second chapter …

Comparing Outcome Of Residential And Intensive Outpatient Treatment Services For Substance Dependence, Shawn E. Channell

Dissertations

The past 20 years have witnessed a significant increase in the number of published studies comparing inpatient with outpatient substance dependence treatment The majority of these studies have reported no benefit for those recipients receiving more intensive treatment However, the outpatient treatment investigated in these studies has typically been day treatment often involving 27 hours a week of participation, and not intensive outpatient treatment (IOP), which involves 12 or fewer hours of participation per week. Additionally, few published studies have compared alcohol and cocaine dependent populations. This study was designed to compare effectiveness of the residential and intensive outpatient levels …

Site-Based Management And Student Achievement, Roxana Marie Hopkins

Dissertations

The question that this study seeks to answer is. Does site-based management increase student achievement? Researchers believe that when a school can function more like a closed system, involved in site-based decision making, the culture of the organization may be more conducive to higher student achievement. This study has attempted to determine if there is a basis for this belief.

Supporting the study are three organization theories. Bureaucracy Theory, Systems Theory, and Human Resource Development Theory. These three theories run like threads in a tapestry throughout the research and legislation upon which this research is developed.

Researchers, up to this …

The Validity Of The Adhd Section Of The Diagnostic Interview Schedule For Children, Ann M. Mcgrath

Dissertations

The purpose o f this study was to learn more about the validity o f the ADHD portion of the NIMH-DISCIV. In order to accomplish this goal, 58 youth participants were divided into three groups: (1) subjects who met criteria for ADHD based upon both the youth and the caretaker versions of the DISC; (2) subjects who met criteria for ADHD based upon the caretaker DISC, but not according to the youth DISC; and (3) subjects who did not meet criteria for ADHD according to either the youth or the caretaker DISC. Subjects in these groups were compared across parent …

Students' Mental Models Of Electricity In Simple Dc Circuits, Andrew C. Isola Iii

Dissertations

This study presents the results of research into middle school students' knowledge about the nature and mechanisms of action of electricity in simple DC circuits. Sixth, seventh, and eighth graders (n=99) were asked a series of questions about the roles of bulbs, batteries, wires, and electricity in circuits. Almost half the number of students (n=42) were found to have used detailed, well-defined, and logically consistent mental models based on their responses. A total of 15 different detailed mental models were documented in these students that belonged to one of four different general model types: (1) round trip flow using both …

Protein And Endotoxin Interactions And Endotoxin Removal From Protein Solutions, Liping Li

Dissertations

The investigation objectives of this study include: endotoxin disaggregation by proteins; protein concentration effect on protein-endotoxin binding and endotoxin removal; size exclusion high performance liquid chromatography (SE-HPLC) studies on endotoxin dissociation by bovin serum albumin (BSA); use of Ca⁺² to re-aggregate endotoxin in hemoglobin solutions and the subsequent removal of endotoxin by ultrafiltration; quantitative determination of Ca⁺² effects on endotoxin removal and protein yield in a two-stage ultrafiltration.

It is known that some proteins can disaggregate endotoxins and form complexes with lipopolysaccharides (LPS). It is also known that Ca can act as "bridges" to aggregate LPS in aqueous …

Skin: A Work Of Fiction, Kellie Wells

Dissertations

In Skin, a polyphonous novel, a community of characters similarly metaphysically vexed and similarly grappling with issues of selfhood and identity intersect and catalyze in one another moments of recognition. These brief self-reckonings suggest to the characters that though the quest to discern their place in the universe is a plagued one, it is not without value as it at least results in faint glimmers of enlightenment. Ultimately, how ever, these flickerings of understanding inch the characters no closer to the big certainties they seek, and they therefore must determine that the process itself, or, more to the point, …