Digital Commons Network^™

Low-Level Pharmaceuticals And Personal Care Products In The Waters Of Michigan, Lisa M. Anderson

Dissertations

The results of this research are the product of a two year study funded by the Michigan Department of Environmental Quality with monies from the Clean Michigan Initiative. Low-level (part per billion range) pharmaceuticals and personal care products (PPCPs) in the waters of Michigan were investigated. Five rivers in the State were sampled; including the Clinton, Grand, Kalamazoo, Muskegon, and Saginaw. Groundwater samples were obtained from two shallow municipal water wells also; one on the Grand River and one on the Kalamazoo River. The wells were sampled to determine if PPCPs in the river water were being drawn in by …

Domestic Violence Rights Movement In Tanzania: An Exploration, Flora Peter Myamba

Dissertations

In Tanzania, the involvement of a social movement to addressing domestic violence is fairly recent (early 1990s) (Green, 1999; Hirsch, 2003; Michau, 2002; TAMWA, 1999). As has historically been the case in most African countries, domestic violence has remained largely invisible, being considered a normal custom, practice and tradition (Green, 1999; The New York Times, 2005; TAMWA, 1999). Efforts to address it have been regarded as shameful and pointless (TGNP, 1993). Indeed, cultural mores remain very contentious with regard to the activities of the Tanzanian domestic violence rights movement (DVRM). It is this conflict between the movement's efforts to educate …

A Study Of Exceptional Mentoring Insights For Adult Education And Emerging Mentors, Laura Lee Larson

Dissertations

The purpose of this critical engagement project was to focus on how mentoring relationships positively impact personal and professional lives -- what I call exceptional mentoring. This was a qualitative study using a narrative inquiry methodology and the theoretical framework of transformational leadership. There were five participants in the study who are known in the industry to be exceptional mentors because of their dedication and passion for caring about others. The research method included one-on-one interviews lasting between two and five hours. The study explored the life stories of these individuals with the intent to learn how people become mentors, …

Climate In Catholic Schools: A Comparative Study Of Three Types Of Organizational Structures, Andra Zommers

Dissertations

This study inquired into American Catholic schools' organizational structures and their relationship with school climate through use of the national data from Schools and Staffing Survey 2003-04 by the National Center for Education Statistics, U.S. Department of Education. The study focused on the statistical assessment of Catholic school teachers' perceptions of climate within three organizational structures. Another aspect of the research was the principals' perception of climate within each of the organizational structures. Last, the study investigated whether teachers' and principals' perceptions of climate differed.

A weighted one-way ANOVA was run to investigate whether the type of Catholic school could …

Characterization Of Natural Organic Matter And Precursors To Trihalomethanes Using Spectral Flourescence Signatures, Krit Punburananon

Dissertations

Disinfection is an essential process to kill pathogens (i.e., disease causing organisms) in source water during the production of drinking water. Chlorine is most widely used disinfectant because it is effective, affordable, and also provides chlorine residual to ensure that the water is safe through the distribution system. Nonetheless, chlorine reacts with Natural Organic Matter (NOM) and forms potentially carcinogenic Disinfection By-products (DBPs). The major chlorination DBPs are dominantly Trihalomethanes (THMs). However, not all organic compounds are equally reactive to THMs formation.

NOM in water samples collected from the Delaware & Raritan Canal and its tributaries (Central New Jersey) was …

Collaborative Learning Utilizing A Domain-Based Shared Data Repository To Enhance Learning Outcomes, David J. Lubliner

Dissertations

A number of learning paradigms have postulated that knowledge formation is a dynamic process where learners actively construct a representation of concepts integrating information from multiple sources. Current teaching strategies utilize a compartmentalized approach where individual courses contain a small subset of the knowledge required for a discipline. The intent of this research is to provide a framework to integrate the components of a discipline into a cohesive whole and accelerate the integration of concepts enhancing the learning process. The components utilized to accomplish these goals include two new knowledge integration models; a Knowledge Weighting Model (KWM) and the Aggregate-Integrate-Master …

Counselor Religiosity And Its Relationship To The Willingness To Encourage Forgiveness And Reconciliation In Clients, Annmarie Cutting

Dissertations

Problem: Although the concept of forgiveness is very old, it has not been systematically studied until fairly recently. As forgiveness therapies and the empirical study of these therapies continue to emerge, the question of the counselor’s own sense of religiosity and forgiveness has not been considered. This study looked at the religiosity of counselors/psychotherapists and how this influences the degree to which they have forgiven an individual who has hurt or offended them, as well as whether a counselor’s religiosity influences their willingness to encourage a client to forgive someone who has hurt or offended them.

Purpose: The purpose of …

Regulation Of Transglutaminase By 5-Ht2a Receptor Signaling And Calmodulin, Ying Dai

Dissertations

Transglutaminase (TGase), nature’s biological glue, catalyzes the post-translational modification of proteins by formation of intra- and intermolecular protein cross-links or by primary amine incorporation. TGase has various physiological functions, such as skin-barrier formation and blood clot stabilization, whereas increasing evidence indicates they may also involved in neurodegenerative diseases including Huntington’s disease (HD), Alzheimer disease’s, and progressive supranuclear palsy. Mutant huntingtin (htt) and small G proteins (e.g. Rac 1) are potential substrates of TGases. The purpose of this dissertation was to characterize the mechanisms by which 5-HT2A receptor signaling and calmodulin (CaM) regulate TGase-catalyzed transamidation of Rac1 and htt in cultured …

A Critical Evaluation Of John Hick's Religious Pluralism In Light Of His Eschatological Model, Haejong Je

Dissertations

Introduction to the Problem

The philosophy of John Hick, who is famous for his religious pluralism, has received vigorous study in terms of its epistemology, authority, the concept of God, and Christology. However, less attention has been given to his pareschatology. As explained below, initial investigation shows that there is a need for in-depth study of Hick’s religious philosophy in this area.

The Problem

Based upon preliminary research, Hick’s religious pluralism seems to reveal a critical problem with external correspondency, as follows. His pareschatology, which is an attempt to accept all eschatologies of major world religions as valid, may as …

An Investigation Of The Perceptions Of Clergy And Laity On Race-Based Organizational Segregation In The Southern Union Conference Of Seventh-Day Adventists, David K. Penno

Dissertations

Problem

The Seventh-day Adventist Church in the United States maintains a racially segregated organization in a society that has intentionally dismantled segregation in most of its organizations. The church needs to evaluate its current conference organization in light of this reality. The purpose of this study was to describe the perceptions of Seventh-day Adventist clergy and members in two conferences in the Southern Union concerning race-based organizational segregation in the church.

Method

This study used a mixed method and was descriptive in design. Four focus groups were conducted to explore the dimensions of the research problem. This step was followed …

The Queer Work Of Fantasy: The Romance In Antebellum America, Zachary Neil Lamm

Dissertations

This project examines the ways in which antebellum writers of romances theorized the relationship between fantasy and queer desire. These writers produced vision of alternative forms of sociality that serve to criticize the heteronormativity of antebellum sexual culture and to promote fantasy as both a mode of critique and a strategy for cultural subversion. Antebellum romances thus represent both a deep dissatisfaction with their author's contemporary culture and a means of envisioning subversive socialities and intimacies that promote freedom of the expression of desire and allow for the queerness that might characterize such expressions if subjects were able to speak …

Moral Reasons Arbitrariness, Brad Seeman

Dissertations

Bradley Nelson Seeman

Loyola University Chicago

MORAL REASONS ARBITRARINESS

The moral philosophies of Allan Gibbard, Christine Korsgaard, and John Post (following Ruth Garrett Millikan's "teleosemantics") each succumb to moral reasons arbitrariness. If a moral philosophy suffers from moral reasons arbitrariness, it fails to establish support relations for moral judgments that uniquely justify those judgments in terms that make essential reference to a person's ability to consider and weigh those support relations in making a moral decision. Moral reasons arbitrariness arises when (1) moral reasons are rooted in factors adventitious to the consideration of support relations, or (2) conflicting moral judgments …

A Rat Model Examining Behavioral And Neurochemical Effects Of Passive Exposure To Aggression On Observers, Hideo Suzuki

Dissertations

Previous studies have consistently reported that passive exposure to aggression is a risk of aggressive inclinations for a human witness. However, it is unclear whether a witness' aggressiveness is semi-permanently socialized or temporarily primed. Furthermore, a neurochemical mechanism of passive exposure to aggression also remains unaddressed in clinical literature. The present research used a rat model to clarify the behavioral and neurochemical effects of passive exposure to aggression. First, rats were screened for their aggressiveness after they were acutely or chronically exposed to aggression or non-aggression. It was found that observer rats chronically exposed to aggression exhibited more aggression than …

Philo Of Alexandria's Exposition Of The Tenth Commandment, Hans Svebakken

Dissertations

As part of a larger exposition on the Ten Commandments, Philo offers in Spec.4.78b-131 a detailed exposition of both the Tenth Commandment, which he reads simply as "You shall not desire," and the Mosaic dietary laws, which he identifies as a distinct set of subsidiary laws designed to promote observance of the Tenth Commandment. Setting his exposition in the context of Middle-Platonic moral psychology, this dissertation answers two fundamental questions: First, what, in Philo's view, does the Tenth Commandment prohibit? (All desire? A certain type? What type?) Second, how, in Philo's view, is the Tenth Commandment observed? (What are the …

The Art Of Trinitarian Articulation: A Case Study On Richard Of St. Victor's _De Trinitate_, Todd D. Vasquez

Dissertations

Richard of Saint Victor deliberately constructs his treatise De Trinitate with trinitarian structures to sustain the hearts and shape the minds of his readers with the contemplation of the Trinity. His work fits within a genre of writing in the Middle Ages where the formation of the theological apprentice was at the heart of crafting one’s theological work. The dissertation consists of three sections: Section I, “Introduction & Background,” establishes the context for the thesis. Chapter one fits Richard’s De Trinitate within the theological heritage of Augustine and Anselm of Canterbury. Chapter two describes aspects of the liturgical and educational …

Cultic Allusions In The Suffering Servant Poem (Isaiah 52:13-53:12), Kyesang Ha

Dissertations

This study investigates the Hebrew cultic allusions in the Suffering Servant Poem (Isa 52:13-53:12) in order to discover the nature or meaning of the suffering of Yahweh's Servant. The survey of literature reveals that the background of the Suffering Servant Poem is to be found in the Hebrew cultus. Thus the nature or meaning of the Servant's suffering is determined by a penetrating as well as comprehensive study of the text, specifically from the Hebrew cultic perspective. However, there has never been any careful, comprehensive study of the cultic allusions in the Poem in connection with the Suffering Servant. This …

Language Attitudes, Linguistic Knowledge, And The Multicultural Education Of Pre-Service Teachers: A Sociolinguistic Study, Maria Elisa Paredes

Dissertations

Abstract This research created, implemented and evaluated the impact of a language unit designed to increase linguistic knowledge and change attitudes toward linguistic diversity for pre-service teachers taking an education class that focused on child and adolescent development at an urban university in Missouri. Both quantitative and qualitative measures were used to document learning and attitude change toward linguistic variety during 4-8 hours of instruction. The language unit included a pretest/posttest design, an overview of general linguistics, phonetics, phonology, sociolinguistics, language acquisition and bilingualism; the unit utilized multiple digital tools (DVD & CD) created by the researcher. Demographic correlates to …

Synthesis And Evaluation Of Structural Analogs Of Escherichia Coli Lipid A For Application Towards Cd14-Targeting Glycotherapeutics, Aileen Fay Galos Bongat

Dissertations

Lipid A is a glucosamine-based phospholipid that anchors carbohydrate molecules to the outer membrane of most Gram-negative bacteria. During severe infection, this amphiphilic macromolecule invoke a strong and acute pro-inflammatory response that leads to sepsis and ultimately to septic shock, organ failure and death. Thus, following the convention that the best antidote is often a derivative of the parent agonistic molecule, researchers have actively pursued the idea of creating an analog of Lipid A that can block the cellular receptor for this molecule and thereby arrest the cascade of events that lead to sepsis. Consequently, we became interested in creating …

Gene Expression Profiles As Molecular Indicators Of Dissolved Oxygen Stress In Grass Shrimp Palaemonetes Pugio Holthuis 1949, Tiandao Li

Dissertations

Occurrence and severity of hypoxia is increasing in coastal and estuarine environments, and recovery of impacted habitats and living resources is slow. Detection of early biological effects of hypoxia is needed for timely remedial action to be taken. The overall objectives of this research was to develop molecular indicators of dissolved oxygen stress to assess the biological impact of hypoxia in coastal estuaries and validate their use through a combination of laboratory and field studies. To achieve these goals, grass shrimp, Palaemonetes pugio, oxygen-sensitive and hypoxia-tolerant species abundant in estuarine systems, were exposed to hypoxia under controlled laboratory conditions, and …

Yellow Head Virus: Transmission And Genome Analyses, Hongwei Ma

Dissertations

Yellow head virus (YHV) is an important pathogen to shrimp aquaculture. Among 13 species of naturally YHV-negative crustaceans in the Mississippi coastal area, the daggerblade grass shrimp, Palaemonetes pugio, and the blue crab, Callinectes sapidus, were tested for potential reservoir and carrier hosts of YHV using PCR and real time PCR. The YHV replicated in the daggerblade grass shrimp, and was still detectable on 36 d post-inoculation, causing 8% mortality after injection. However, YHV did not replicate in the blue crab. These data suggest that the daggerblade grass shrimp could act as a reservoir host for YHV. Storage conditions of …

Examination Of An Aloe Vera Galacturonate Polysaccharide Capable Of In Situ Gelation For The Controlled Release Of Protein Therapeutics, Shawn David Mcconaughy

Dissertations

A therapeutic delivery platform has been investigated with the ultimate goal of designing a sustained protein release matrix utilizing an in-situ gelling, acidic polysaccharide derived from the Aloe vera plant. The Aloe vera polysaccharide (AvP) has been examined in order to determine how chemical composition, structure, molecular weight and solution behavior affect gelation and protein/peptide delivery. Correlations are drawn between structural characteristics and solution behavior in order to determine the impact of polymer conformation and solvation on gel formation under conditions designed to simulate nasal applications. Steady state and dynamic rheology, classic and dynamic light scattering, zeta potential, pulse field …

Flexography Printing Of Silver Based Conductive Inks On Packaging Substrates, Ramesh Chandra Kattumenu

Dissertations

Printing technologies for the production of flexible electronics have gained much interest due to its potential as a means to reduce the complexity and costs of present technology. High volume printing techniques like flexography are of great importance in order to produce rolls of flexible electronics printed directly on paper substrates. The proposed research will be focused on RFID components being in-line printed using flexography printing as the manufacturing platform. The properties of substrates and inks and printing process parameters are evaluated to study their effect on printed traces and RFID antenna. It was found in the study that properties …

Construction Of A New Model System In Saccharomyces Cerevisa To Study Yopo And Identify Its Targets, Laura Nejedlik

Dissertations

Yersinia species use a type three secretion system (TTSS) to inject Yersinia outer proteins (Yops) into the target cell. The effector YopO is a serine/threonine kinase which upon association with actin becomes active. However, activation of the kinase is not required for actin disruption. YopO also contains a Rho/Rac binding domain, but it is unclear how it affects these proteins.

We have established an expression system in Saccharomyces cerevisiae to study YopO. The expression vector contains a GAL1 promoter for inducible expression of YopO as well as a V5 epitope used for visualization of each Yop. We have shown that …

Evaluation Of Electron Donor Materials Used To Create Subsurface Permeable Reactive Barriers For Enhanced Reductive Dechlorination Of Chlorinated Ethenes, Elizabeth S. Semkiw

Dissertations

Chlorinated ethenes (CEs) are widespread ground water contaminants, apparently due to their extensive migration from numerous contamination source points. In this study, a long-term field investigation and aquifer microcosm experiments were combined to evaluate the effectiveness of electron donor materials used to create and maintain subsurface permeable reactive barriers (PRBs) for the enhanced in-situ biodegradation of CEs. The laboratory component includes the first side-by-side comparison of electron donor materials dairy whey, lactate syrup, and Hydrogen Release Compound® (HRC), in which dechlorination rates, fermentation product distributions, and H₂ production were monitored as measures of substrate efficiency. Field study allowed the …

Switch On And Switch Off Nanosensors For The Detection Of Nerve Gas Agents, Shankar Varaganti

Dissertations

The central hypothesis of this research is the development of novel nanosensors by a bottom-up approach for the detection of nerve gas agents. The nanosensor assembly consists of four main parts; nanoparticles (N), Monomer (M), Complex (C) and Receptor (R). Two novel Ru (II)-bipyridyl and zinc complexes with tryptophan receptors either in 4,4' or 5,5' position of the bipyridyl ring have been synthesized and characterized by using ¹H NMR, ¹³C NMR, mass spectrometry and absorption spectroscopy. Silica nanoparticles or quantum dots are used as a platform for the nanosensors. Highly conjugated stilbene type compounds are used as monomers. …

Sense Of Humor, Stress And Coping, And Outcomes In Children's Lives, Lambertha Okhuizen-Stier Phd, Mph, Rn

Dissertations

Children are confronted with many stressors in their environment which may bring about symptoms such as anxiety, sadness, worry, aggressiveness, hyperactivity, restlessness, or low self esteem (Sharrer & Ryan-Wenger, 2002). To prevent the short and long term effects of stress, children may use coping strategies to manage or alter stressful life events (Lazarus & Folkman, 1984). This study explores the relationships between stress and sense of humor among school-age children. A sample of 106 students (and parents/guardians) in the San Diego Unified School District (SDUSD) returned self-report instruments packets containing the Multidimensional Sense of Humor Scale for Children, and the …

Homefront, Stacy Elaine Pratt

Dissertations

This collection of poetry and essays explores the nature of marriage, time, and human experience. Many of the pieces center on the author's experience as the wife of a soldier deployed to Iraq and Afghanistan. Others use scientific and mathematical imagery to illustrate spiritual concepts.

Development Of A Workflow For The Comparison Of Classification Techniques, Zanifa Omary

Dissertations

As the interest in machine learning and data mining springs up, the problem of how to assess learning algorithms and compare classifiers become more pressing. This has been associated with the lack of comprehensive and complete workflow depending on the project scale to provide guidance to its users. This means the success or failure of the project can be highly dependent on the person or team carrying it.

The standard practice adopted by many researchers and experimenters has been to follow steps or phases from existing workflows such as CRISP-DM, KDD and SASSEMMA. However, as machine learning and data mining …

A Mathematical And Computational Exploration Of The Effect Of The A-Current In Determining The Activity Phase Of Follower Neurons, Yu Zhang

Dissertations

Bursting oscillations are prevalent in neurons of central pattern generators (CPGs) that produce rhythmic motor activity, and the activity phase plays an important role in determining the normal or dysfunctional network output. The activity phase is the delay time-with respect to some reference time in each cycle and normalized by the oscillation cycle period-of the onset of action potentials by a neuron. This dissertation investigates how the A-current, in conjunction with other intrinsic properties, sets the activity phase of a neuron driven by inhibition.

This dissertation is divided into two major components. In the first component, methods of dynamical systems …

Review Of The Genus Polycheria Haswell, A Symbiotic Group Of Amphipods (Crustacea: Dexaminidae) With Descriptions Of New Species From Florida, The Caribbean Sea, And The Indo-Pacific Region, John Milton Foster

Dissertations

Systematics and taxonomy of the dexaminid amphipod genus Polycheria Haswell (Dexamindae: Amphipoda), whose members are cosmopolitan associates of tunicates and sponges, are confused. This is due in large part to the many inadequate and incomplete descriptions and poorly some executed illustrations, especially for the early studies on the group. Previously, 22 nominal species or forms have been described or designated in the literature. The purpose of this study is to critically review and clarify the systematics of this enigmatic genus. Based on personal collections and on specimens from museums, five new species are designated and 22 species or forms are …