Digital Commons Network^™

Investigating The Functional Role Of Tick Antioxidants In Hematophagy And Vector Competence, Deepak Kumar

Dissertations

Ticks are obligate hematophagous arthropods and harbor several pathogens which transmit various diseases to humans and their domesticated animals. Host blood- digestion in a tick midgut (MG) generates several reactive oxygen species (ROS), which are extremely toxic to essential macromolecules (e.g. DNA, proteins, and lipids) within the cell, resulting in high oxidative stress. Thus, this dissertation focuses on the questions of how tick homeostasis responds to high oxidative stress, and how ticks and their harbored pathogens survive the high surge of oxidative stress during blood digestion. We are specifically interested in the tick-pathogen, Rickettsia parkeri (R. parkeri, Rp), harbored by …

Examining Teachers' And College Students' Perspectives Toward E-Textbooks As An Educational Tool, Nariman Ali Alawami

Dissertations

The purpose of this research was to understand the perspectives of teachers and students regarding their use of specific e-textbooks in a higher education learning environment. The e-textbooks used by the teachers and students were examined in order to determine functions and features to focus on during the inquiry. This study was particularly interested in the design of e-textbooks and how they are used by both teachers and students in the learning process. The participants in the research were also prompted to suggest improvements to e-textbooks. A case study approach was used as the methodology to examine three teachers represented …

Biology Laboratories At A Distance: A Case Study And Experiment Of Ecology And Evolution Labs With Community College Students, Beverly E. Ranney

Dissertations

Community colleges deliver more courses online; laboratory-based courses face challenges in how to do this. This study examined how ecology and evolution laboratories could effectively be delivered in an online biology community college course. Virtual simulations and hands-on, at-home kits were used in two groups. Results showed that students using the virtual simulations had higher learning gains and more positive perceptions towards their laboratory experiences than those students using athome kits. By evaluating learning gains on a pretest/posttest and utilizing interviews and focus groups, this research concluded that virtual simulations offered a superior learning experience for online learners. The results …

The Effects Of Punishment On Resistance To Change And Reinstatement, Tomesha A. Manora

Dissertations

Resistance to change (RTC) refers to the persistence of behavior when environmental changes disrupt responding. Studies have shown that RTC varies as a function of the reinforcement associated with the context, with higher rates and magnitudes of reinforcement generating greater response persistence. Resistance to change has been shown to be related to reinstatement, or the increase in responding during extinction when responses are followed by noncontingent reinforcement. Little research has investigated whether punishers have equivalent yet opposite effects as reinforcers on response persistence and reinstatement. The present study investigated the effects of electric shock punishment on resistance to change and …

A Qualitative Study Analysis On How Utilizing A Token Economy Impacts Behavior And Academic Success, Solomon Defrancis Dr.

Dissertations

Utilizing a qualitative study analysis, this study examines how behavior impacts academic success utilizing a token economy with students who suffer from emotional disturbance disorder. Through focus groups of para educators, therapists and teachers on special education settings, there will be a comparative analysis of behavior and academic success. The study will consist of six education sites throughout the Antelope Valley: A kindergarten through eighth grade (Yellen Learning Center), a kindergarten through sixth grade elementary (Valley View Elementary), a seventh through eighth grade intermediate school (Joe Walker) and three high schools that are ninth through twelfth grade (Desert Pathways, Palmdale …

Action Research Using Entomological Research To Promote Hands-On Science Inquiry In A High-Poverty, Midwest Urban High School, Dustin Stockmann

Dissertations

The purpose of this mixed-methods action research study was to examine to what extent entomological research can promote students’ hands-on learning in a high-poverty, urban, secondary setting. In reviewing the literature, the researcher was not able to find a specific study that investigated how entomological research could promote the hands-on learning of students. The researcher did find evidence that research on learning in a secondary setting was important to student growth. It should also be noted that support was established for the implementation of hands-on science inquiry in the classroom setting. The study’s purpose was to aid educators in their …

Using Spatialisation To Support Exploratory Search Behaviour, Clement Roux

Dissertations

Information-seekers traditionally interact with digital content through keyword-based search interfaces displaying results in list views. Well-defined lookup search tasks are performed brilliantly with these interfaces, enabling users to find relevant information and develop a relative understanding of the underlying information space. However, it is feasible to suggest that ill-defined and abstract search tasks could be better supported with a different interface that could allow the user to explore a library’s content and develop an appropriate mental model of the information space. One such approach is based on the use of visualisation, an approach to data analysis that aims to reduce …

Investigating The Impact Of Unsupervised Feature-Extraction From Multi-Wavelength Image Data For Photometric Classification Of Stars, Galaxies And Qsos, Annika Lindh

Dissertations

This thesis reviews the current state of photometric classification in Astronomy and identifies two main gaps: a dependence on handcrafted rules, and a lack of interpretability in the more successful classifiers. To address this, Deep Learning and Computer Vision were used to create a more interpretable model, using unsupervised training to reduce human bias.

The main contribution is the investigation into the impact of using unsupervised feature-extraction from multi-wavelength image data for the classification task. The feature-extraction is achieved by implementing an unsupervised Deep Belief Network to extract lower-dimensionality features from the multi-wavelength image data captured by the Sloan Digital …

An Exploration Of The Impact Of Animal Agriculture On Human Sustainable Development Index And The Child Health Indicator, Hithesan Pandian

Dissertations

Several studies have shown that animal agriculture is one of the major contributors to climate change due to greenhouse gas emissions, deforestation, land degradation, freshwater shortages, general environmental pollution and world hunger. Apart from this, meat consumption is strongly associated with certain fatal health conditions such as cancer, cardiovascular disease and diabetes (Wu, 2014). Although meat production and export could be economically beneficial in the short run, it could lead to over-exploitation of natural resources and in turn the destruction of the environment in the long run. Hence, it is essential for the leaders of a nation to make smart …

In Vivo And In Vitro Studies Of Polyamides That Are Active Antiviral Agents Against Hpv16, Edith Csiki-Fejer

Dissertations

Long-term, persistent infection with high-risk strains of human papillomavirus (HPV) is the precursor of most cervical cancers and an increasing number of the head and neck cancers. While HPV vaccines can protect patients under twenty-five years old from possible infections, no HPV antiviral drugs are available for the definitive treatment of preexisting or future viral infections. To treat current or future HPV infections, drugs that selectively block virus-specific processes, but do not damage the host cells, are needed. The compounds developed in our group are unique Imidazole-pyrrole polyamides, analogs of natural products Distamycin A and Netropsin that function by interfering …

Processing Of Cds/Cdte Solar Cell And The Growth Model Of Cdte Thin Film, Guogen Liu

Dissertations

Cadmium telluride is the only thin film photovoltaic (PV) technology to surpass crystalline silicon PV in the cost. The most common CdTe solar cells consist of a simple p-n heterojunction structure containing a p-doped CdTe layer and n-doped cadmium sulfide (CdS) layer, which acts as a window layer. Cadmium Sulfide (CdS) thin films are often deposited on glass substrates coated with TCO layers by the close-spaced sublimation (CSS) or sputter techniques in industrial because of in-line production integration. It is seldom reported that CdS is deposited by the chemical bath deposition (CBD) batch process. The bottleneck of CBD for commercial …

Biomimetic And Vascularized 3-D Liver Cancer Model, Derek Yip

Dissertations

Anti-angiogenic drugs have failed to show significant extended mortality, except when co-administered with chemotherapy drugs in clinical trials. This should be predicted by in vitro models, and yet 2D in vitro models of liver cancer co-administered with these two types of drugs show increased cell viability, contradicting clinical trials. In vitro models should mimic clinical trials in order to accurately predict drug outcomes. 2D in vitro models fail because they lack features of the cancer environment such as presence of stromal cells and a vasculature.

In order to achieve a biomimetic and vascularized in vitro model that would better recapitulate …

Algorithms For Pre-Microrna Classification And A Gpu Program For Whole Genome Comparison, Ling Zhong

Dissertations

MicroRNAs (miRNAs) are non-coding RNAs with approximately 22 nucleotides that are derived from precursor molecules. These precursor molecules or pre-miRNAs often fold into stem-loop hairpin structures. However, a large number of sequences with pre-miRNA-like hairpin can be found in genomes. It is a challenge to distinguish the real pre-miRNAs from other hairpin sequences with similar stem-loops (referred to as pseudo pre-miRNAs). The first part of this dissertation presents a new method, called MirID, for identifying and classifying microRNA precursors. MirID is comprised of three steps. Initially, a combinatorial feature mining algorithm is developed to identify suitable feature sets. Then, the …

Genetic Risk For Increased Oxidative Stress In The Aging Brain:Implications For White Matter Integrity And Cognition, Lauren Salminen

Dissertations

Oxidative stress is a key mechanism of the aging process that can cause damage to brain white matter and cognitive functions. Allele variations of two polymorphisms (SOD2, CAT -262) have been associated with abnormalities in antioxidant enzyme activity, suggesting a risk for enhanced oxidative damage to brain white matter and cognition among older individuals with these genetic mutations. The present study utilized diffusion tensor imaging (DTI) and neuropsychological assessment to compare differences in microstructural white matter integrity and cognitive performance among 96 older adults (age 50-85) with and without genetic risk factors of SOD2 (rs4880) and CAT -262 (rs1001179). Results …

Investigations Of Storage Root Development In Cassava (Manihot Esculenta Crantz), Yeetoh Chaweewan

Dissertations

The tropical root crop cassava is cultivated for its large starchy storage roots. Understanding critical processes in root tuberization is essential if improvement programs are to secure future yields for farmers. Studies were undertaken to identify critical components of storage root development at the anatomical and gene expression levels. Two types of roots were identified from greenhouse-grown stem cuttings: basal roots, which develop from the stem cut end and are prolific in nature, and nodal roots, which originate from the region of the buried axillary bud. Only nodal roots develop to produce storage organs. Anatomical sectioning was performed to determine …

Health-Risk Behaviors And Bmi Percentiles, Timothy Mikando Makubuya

Dissertations

This study examined the relationship between Body Mass Index (BMI) percentile and health risk behaviors of physical activity, dietary behaviors and sleep among high school students from the Youth Risk Behavioral Survey. The study used the 2013 National Youth Risk Behavioral Survey data from the U.S. Center for Disease Control and Prevention (CDC). The researcher used data for 9th to 12th graders to examine the associations between physical activity, dietary behavior, sleep and BMI percentiles among those participants using a measure of Spearman’s Rho correlation and Multiple Linear Regression analysis. There were significant indirect associations between physical activity, dietary behavior …

Black Spaces In White Places: Toward Black Educational Imagination, Shenita Nicole Mayes

Dissertations

Using a combination of Critical Race Theory, self-determination, and Black radical imagination as a theoretical framework, this dissertation explores how the features of Black educational imagination – liberatory pedagogy, critically conscious acts, and a revitalized Black teaching force – animate Black school space. These spaces facilitate the re-humanization of Black people, the recognition of counter-narratives as valuable, and the consideration of racial trauma in hiring practices. Each space represents a meaningful recognition of Black radical imagination and therefore inform my actions in the workplace. I argue that a possible path towards liberating Black people from racialized oppression is paved by …

Effects Of Human Disturbance On Physiology, Behavior, And Ornamentation In The Eastern Bluebird, Lauren Marjorie Gillespie

Dissertations

Overall, few studies have focused on anthropogenic disturbance on wildlife physiology. Research has typically focused on how environmentally contaminated areas or anthropogenic disturbance (e.g. noise, human activity) influences biodiversity, community structure and behavior of individual animals. However, understanding how disturbance influences some aspects of physiology can require sacrifice of the animal, prohibiting ecologically relevant measures of behavior and reproductive success. This research strives to examine covariation between testosterone (T) and corticosterone (CORT), plumage ornamentation, and behavior in two populations of eastern bluebirds (Sialia sialis) that differ in degree to which their habitat is modified by human activity.

In …

Mitigating The Effects Of Test Anxiety Through A Relaxation Technique Called Sensory Activation, Marylynne Abbott

Dissertations

Test anxiety is a phenomenon which has been researched for decades. Student performance, goal attainment, and personal lives are all negatively affected by the multiple factors of test anxiety. This quantitative study was designed to determine if a particular relaxation technique, called sensory activation, could mitigate the symptoms and effects of test anxiety. The Test and Anxiety Examination Measure, developed by Brooks, Alshafei, and Taylor (2015), was used to measure test anxiety levels before and after implementation of the sensory activation relaxation technique. Two research questions guided the study using not only the overall test anxiety score from the Test …

Therapeutic And Safety Evaluation Of Curcumin's Antimicrobial And Anti-Inflammatory Properties On Canine And Equine, Stephanie Bland

Dissertations

In total, four experiments were conducted to determine the therapeutic and safety effects of the nutraceutical, turmeric and its active ingredient curcumin on canine and equine. Two studies were conducted on client-owned, moderately arthritic canines, studying the therapeutic and safety effect of curcumin’s anti-inflammatory properties. In Exp. 1, two different dosages, 500 mg, SID of 95% curcumin and 250 mg, BID of 95% liposomal-curcumin, were evaluated in ten moderately arthritic dogs over five months. The dogs in the 95% curcumin group had an overall greater significance in pain reduction by Day 60. Exp. 2, was a follow-up experiment to Exp. …

Discriminative Stimulus Effects Of 3,4-Methylenedioxypyrovalerone And 4-Methylmethcathinone, Michael D. Berquist

Dissertations

Recent escalation in the popularity of recreational synthetic cathinone (“bath salts”) use has prompted numerous scientific investigations of the neurochemical and behavioral effects of 3,4-methylenedioxypyrovalerone (MDPV) and 4-methylmethcathinone (4-MMC), two of the more common chemical constituents of these illicit “bath salts”. Previous neurochemical and electrophysiological studies have revealed that MDPV functions as a blocker, and 4-MMC as a substrate, at monoamine transporters, and both produce transient increases in extracellular monoamines. In addition, previous research has demonstrated that MDPV and 4-MMC support self-administration in nonhuman experimental subjects, and their rewarding effects are observed when paired with contextual cues in nonhuman models …

Assessing Change In Attachment Security Of Adolescents At Residential Therapeutic Programs, Laura Santa Thum

Dissertations

Adolescents with significant, persistent behavioral and mental health problems are increasingly being treated in private residential treatment programs (RTPs). Recent research at such programs shows that adolescents’ symptoms improve over the course of treatment and that such positive results persist up to a year post discharge. This study attempts to address what is occurring below the symptom level by exploring if attachment security increases as symptoms improve over the course of treatment in private RTPs. The level of attachment security was assessed along the dimensions of attachment avoidance and anxiety as a general construct and according to specific relationships (with …

Establishing And Testing Conditioned Reinforcers: Evaluating The Effects Of The Discriminative Stimulus Procedure Using Intermittency With Individuals With Developmental Disabilities, Yannick A. Schenk

Dissertations

A common characteristic of individuals with developmental disabilities is a restricted range of interest. Developing procedures to establish new reinforcers for such individuals can promote the acquisition of new skills and ameliorate decreases in motivation related to satiation. Several procedures for conditioning reinforcers have shown to be effective in the research literature for establishing neutral stimuli as conditioned reinforcers. Most of this literature is basic research with animal subjects (e.g., rats, pigeons). Few applied studies have directly evaluated the use of these procedures. Additional research is necessary to determine their effectiveness. The purposes of this study were to: (a) evaluate …

Rising Against The “Enemies Of The Church”: The Dynamics Of Russian Desecularization And The Making Of Its Punitive Regime, Rachel Lynn Schroeder

Dissertations

This study makes an original contribution to theorizing desecularization, which Karpov (2010) defines as “a process of counter-secularization, through which religion reasserts its societal influence in reaction to previous and/or co-occurring, secularizing processes.” Existing theory states that desecularization is agency driven, involves social actors and activists with specific interests, ideologies and strategies. However, the theory does not explain the dynamics whereby desecularization takes place and a particular desecularizing regime—in structural and normative form and symbolic and discursive content—develops through social action and achieves hegemonic status. This dissertation fills this important gap by asking: How and why, in the anomic post-Soviet …

An Evaluation Of The Acceptability And Effects Of A Computer-Delivered Values-Based Behavioral Activation Treatment For Depression Among Older Adults, Kellie Reynolds

Dissertations

Depression is a common psychological disorder among older adults and is associated with serious secondary effects to health and social well-being. Behavioral activation has been found to be an efficacious treatment for depression. However, there is limited research on the treatment effects of behavioral activation with older adults. In general, older adults under-utilize mental health treatments. Computer-delivered treatments have been developed to address access and under-utilization. The purpose of this dissertation was to evaluate the acceptability and effects of a computer-delivered values-based behavioral activation treatment for depression in older adults. This study consisted of two phases. Phase I consisted of …

Increasing Caregiver Supervision Of Young Children: Teaching Scanning, Predicting Behavior, And Modifying For Safety, Natalie Truba

Dissertations

Unintentional injuries account for a significant number of child deaths and visits to the emergency department. Although increased supervision is routinely shown to be an effective method of preventing unintentional childhood injuries, few interventions systemically teach caregivers behavioral skills to supervise their children appropriately. The present study utilized a multiple baseline design to pilot test an intervention designed to increase caregiver supervision and decrease unintentional childhood injuries by training caregivers how to provide appropriate levels of supervision for their young children (ages 6 to 36 months). Specifically, caregivers were taught in the present study include: (1) scanning the environment (for …

The Lived Experience Of Individuals With Chronic Back And Neck Pain, Depression, And/Or Anxiety, Tara L. Palmeri

Dissertations

More than 1.5 billion people worldwide suffer from chronic pain (CP). People who experience chronic pain are 20 to 40% more likely to meet criteria for an anxiety disorder, and three to four times more likely to be clinically depressed than their pain-free counterparts. The relationship between CP and mental health has been studied quantitatively; however, few researchers have investigated co-morbid CP and mental health through a phenomenological lens. The subjective nature of the relationship is not comprehensively addressed within the literature.

This qualitative phenomenological study explored (a) how individuals with chronic back and/or neck pain (CBNP) experience, understand, and …

Culturally Relevant Education For Rural Schools: Creating Relevancy In Rural America, Joshua J. Anderson

Dissertations

In this dissertation, I investigate the ways in which culturally relevant pedagogy is conceptualized and implemented by two secondary English Language Arts educators in one school district with a strong sense of rural identity. Culturally relevant pedagogy is considered by many professionals in the field of education to be an effective philosophy to inform instructional practices for narrowing the achievement gap of historically marginalized groups (Cummins, 1990; Gay, 2000; Ladson-Billings, 1994, 2000). A careful review of the literature on culturally relevant pedagogy reveals the discourse surrounding culturally relevant pedagogy has largely been dominated by urban voices (Cochran-Smith, 2003; Esposito & …

Natural Disasters In Latin America: The Role Of Disaster Type And Productive Sector On The Urban-Rural Income Gap And Rural To Urban Migration, Madeline Alice Messick

Dissertations

This research provides insight into the impact of natural disasters as drivers of rural to urban migration in Latin America and the Caribbean (LAC). Disasters of varying types are predicted to have differing impacts on the productive sectors of agriculture, industry, and services; which due to the concentration of the various productive sectors in either urban or rural areas, subsequently changes the urban-rural wage differential. Changes to the wage differential (as measured by the urban-rural income gap) are predicted to lead to movement between urban and rural areas until a new equilibrium wage is reached.

This dissertation first identifies a …

Ecological And Phenotypic Factors Influencing The Movement Dynamics Of The Blackspotted Topminnow, Fundulus Olivaceus, Scott Richard Clark

Dissertations

Movement of individuals throughout a landscape is a complex behavior that has important consequences on numerous ecological and evolutionary processes. Perhaps most notably is the relationship between movement and reproduction, as this has implicit ramifications on individual fitness and consequently, population level processes. Although this relationship has been theoretically and empirically demonstrated across a number of animal taxa, its role in fishes remains understudied and largely unknown. Using a series of outdoor mesocosms, in combination with a field study, I employed passive integrated transponder (PIT) tags to experimentally assess the sex-specific movement dynamics of a small-bodied, sexually-dimorphic stream fish, the …