Digital Commons Network^™

The Theological Significance Of The Relations Of Freedom And Time In The Sciences And Humanities: An Evaluation Of The Contributions Of David Bohm And Pauli Pylkko, Michael F. Younker

Dissertations

The concepts of freedom and time underlay all other philosophical and theological questions. This dissertation addresses the natures and relations of freedom and time and their impact upon theological reflection, primarily through the works of the philosopher of science, David Bohm and the philosopher of the humanities, Pauli Pylkkö. These two representatives come from the two competing cultures of the sciences and humanities, which illustrate the deep philosophical conflict that has emerged between these cultures concerning the natures of freedom and time. Specifically, the paradigmatic contributions of Albert Einstein's four-dimensional 'timeless space-time' (with timeless freedom) alongside Bohm, on the one …

Sources And Atmospheric Oxidation Of Sulfur Dioxide And Formaldehyde Based On Wintertime Aircraft Observations Over The Eastern United States, Jaime R. Green

Dissertations

Plume intercepts from flights on the NSF-C-130 during the Wintertime Investigation of Transport, Emission and Reactivity (WINTER) campaign were used to estimate (1) the oxidation rates of Sulfur Dioxide (SO₂) under wintertime conditions and the factors that determine SO₂ removal; and (2) to examine the oxidation, lifetime and source apportionment of formaldehyde (HCHO). Observations suggest that OH governs the rate SO₂ oxidation in the eastern United States during winter. The range of mean oxidation rates during the day from power plants were 0.22–0.71%/hr, producing SO₂ lifetimes of 13–43 days, if SO₂ consumption is assumed …

Investigation Into The Perceptually Informed Data For Environmental Sound Recognition, Chenglin Kang

Dissertations

Environmental sound is rich source of information that can be used to infer contexts. With the rise in ubiquitous computing, the desire of environmental sound recognition is rapidly growing. Primarily, the research aims to recognize the environmental sound using the perceptually informed data. The initial study is concentrated on understanding the current state-of-the-art techniques in environmental sound recognition. Then those researches are evaluated by a critical review of the literature. This study extracts three sets of features: Mel Frequency Cepstral Coefficients, Mel-spectrogram and sound texture statistics. Two kinds machine learning algorithms are cooperated with appropriate sound features. The models are …

Generating Cyberattack Model Components From An Attack Pattern Database, Tymaine S. Whitaker

Dissertations

The number, variety, sophistication, and consequences of cyberattacks are all growing. The developers and users of computer systems should have some knowledge of the different types of cyberattacks that can occur. Models of cyberattack patterns can contribute to that knowledge. Executable models of cyberattacks used to simulate the attacks can reveal system vulnerabilities and improve decisions made by both attackers and defenders during attacks. One type of cyberattack model, Attack Trees, supports visualization and formal analysis of cyberattacks. A second type of model, Petri nets with Players, Strategies, and Costs (PNPSC), was developed specifically for cyberattack modeling as part of …

Reinforcement Learning Applied To Manufacturing Material Handling, Swetha Govindaiah

Dissertations

Applying machine learning methods to improve the efficiency of complex manufacturing processes, such as material handling, can be challenging. The interconnectedness of the multiple components that make up such processes and the typically large number of variables required to specify procedures and plans within them combine to make it very difficult to map the details of a real-world manufacturing process to an abstract mathematical representation suitable for machine learning methods. This work comprises both applied and theoretical results. On the applied side, machine learning, in particular reinforcement learning, was used to generate increasingly efficient plans for material handling to satisfy …

Analytical Aeroelastic Models For Chordwise And Spanwise Flexible Flapping Wings In Forward Flight, Deepa Kodali

Dissertations

Animal wings deform significantly during flight. However, the aerodynamic features of flexible wings interacting with the surrounding fluid have not been adequately explored. One of the main challenges in predicting aerodynamic forces is that the wing shape and motion are a priori unknown. In this dissertation, two-way coupled analytical fluid-structure interaction models for chordwise and spanwise flexible flapping wings in forward flight are derived. The unsteady aeroelasticity is modeled with the Euler-Bernoulli beam and Theodorsen equations under the small deformation assumption. The two-way coupling for a chordwise flexible airfoil is realized by considering the trailing-edge deformation relative to the leading-edge …

Daxx As A Restrictor Of Tumor Initiating Cell Survival In Er+ Breast Cancer And Its Therapeutic Implications, Daniel Seamus Peiffer

Dissertations

Breast cancer overall is the second most common cause of cancer related death in women, with one in eight women being diagnosed during their lifetime. Breast cancer itself is divided into subtypes based on the expression levels of the hormone receptors including the estrogen receptor (ER) and the progesterone receptor (PR), as well as expression of the growth factor receptor epidermal growth factor receptor 2 (HER2). ER+ breast cancer is the most common breast cancer diagnosis, and these tumors are defined as being initially dependent on activation of the receptor for growth. Based on this, targeted endocrine therapies (ETs) have …

Measuring And Evaluating Directional Textures And Using Them In Visual Discovery, Manil Maskey

Dissertations

This dissertation focuses on three aspects of directional textures. The first aspect is the development of a new directional texture-based visualization technique to address challenges in visualizing multivariate data in a single display. The technique uses a multi level Markov Random Field-based texture synthesis to progressively generate a visualization that encodes data variables using various texture features, especially texture direction. Since texture directionality has not been used extensively in visualization, this technique provides a new visual cue to display additional data variable in a single display. Evaluations of the new texture-based visualization technique are also presented. The second aspect is …

Characterization Of Putative Peptidyl-Trna Hydrolase Domain Containing 1, Geordan L. Burks

Dissertations

Putative peptidyl-tRNA hydrolase domain containing 1 (PTRHD1) is a eukaryotic protein predicted to be a Pth2-like peptidyl-tRNA hydrolase. Peptidyl-tRNA hydrolases (Pth) perform the essential function of recycling tRNA from peptidyl-tRNA in the event of translational failure. This function is ubiquitous in all domains of life. Homologues of bacterial (Pth1) and archaeal (Pth2) Pths are present in eukaryotes; however, simultaneous knockout of Pth1 and Pth2 has no effect on cell viability, suggesting the presence of additional proteins in eukaryotes that contain Pth activity. PTRHD1 was proposed as one such eukaryotic Pth and was tested for Pth hydrolase activity. While PTRHD1 did …

Constructing A Theology Of Relational Life Through The Themes Of Creation, Incarnation, And Re-Creation As An Alternative To Current Categories Of Religions, Andrew Tompkins

Dissertations

This dissertation argues that current categories of religions are overly reliant on Western Enlightenment-based presuppositions and academic thinking that creates barriers in understanding God’s desire for all people to have abundant life. Many theologians and missiologists utilize these inherited categories without first subjecting them to the biblical canon. As a result, the theological and missiological discourse on religions is often grounded in extra-biblical presuppositions rooted primarily in an overly high view of human reason that do not accurately portray a biblical approach to relational life. These presuppositions do not accurately portray a biblical approach to relational life. I, therefore, compared …

"Let Us Make 'Adam": An Edenic Model Of Personal Ontology, Marla A. Samaan Nedelcu

Dissertations

Personal ontology studies human constitution and human nature, an increasingly debated topic in Christian theology. Historically, the most prominent models of personal ontology in Christian theology have been substance dualist models. More recently, physicalist models have offered prominent alternatives.

This dissertation studies the conflict of interpretations between these two major model groupings. By applying a canonical theology, it then presents an Edenic model of personal ontology that can address the current conflict of interpretations. To achieve this end, the dissertation briefly analyzes substance dualism and physicalism according to the rubrics of constitution and nature, using a model methodology. It then …

Aerococcus Urinae: Establishing The Pathogenesis Of An Emerging Uropathogen, Evann E. Hilt

Dissertations

Urinary tract infection (UTI) is the world's most common bacterial infection. Much is known about the infectious process (pathogenesis) of a few of the bacteria that cause these infections, especially E. coli. Unfortunately, the pathogenesis of E. coli and other uropathogenic bacteria was explored almost exclusively in the belief that the bladder is supposed to be sterile. Our recent evidence, however, debunks this dogma. We used modern methods to reveal diverse bacterial communities in the bladders of adult women. These communities differ in women with and without lower urinary tract symptoms (LUTS), including UTI and urinary incontinence (UI). Many bacteria …

The Social And Contextual Mechanisms Of Children's Learning In Museums, Lindsay R. Maldonado

Dissertations

This study explored the associations between immersive exhibit design, mother-child engagement, conversational interactions, and children's learning. Participants were 41 mothers and their 6-8-year-old children (Mage=7.15, SD=.79). A within-subjects, mixed methods approach was utilized, including naturalistic observations, interview data, and surveys. Mother-child dyads were video and audio-recorded as they visited four different exhibits: two low immersion exhibits and two high immersion exhibits. Interview data was collected from children immediately following the visit to assess learning. Survey data was collected from mothers to assess education, environmental predispositions, and science-related career. In high immersion exhibits, mothers and children spent more time and asked …

Characterization Of The Effects Of Sex And Estrogen Receptor Signaling On Antigen-Specific T Cells For Immunotherapy, Flor Cecilia Navarro Negredo

Dissertations

Adoptive cell transfer (ACT) immunotherapy using antigen (Ag)-specific T cells is partially effective treating several malignancies but numerous challenges remain in order to improve its therapeutic potential. The roles of host factors, such as sex hormone receptor signaling, that can affect the T cell anti-tumor function remain understudied. The work performed in this dissertation characterized the role of estrogen signaling on T cell function in vitro, and during ACT immunotherapy against hepatocellular carcinoma (HCC) in vivo. Estrogen signaling through ERa enhanced the expression and secretion of Type I effector cytokines including IFNg, TNFa, and Granzyme B in male and female …

Protection From Staphylococcus Aureus Bloodstream Infection By Probiotic Exopolysaccharide, Wonbeom Paik

Dissertations

Staphylococcus aureus is known to cause severe systemic infection with high mortality rates. Antibiotics are the only approved therapy for patients, but the widespread prevalence of antibiotic resistant strains limits treatment efficacy, and many patients succumb to the disease. Many probiotic agents are commercially available, but the mechanisms by which they benefit are not known. Understanding these mechanisms will help develop novel therapeutics that can improve healthcare, including systemic infections by S. aureus. Bacillus subtilis is a probiotic bacterium that produces an exopolysaccharide (EPS) that induces anti inflammatory macrophages (MΦ). We tested if EPS could be used for systemic S. …

Yczr, A New Case Of Plp-Dependent Mocr/Gabr Type Transcription Regulator In Klebsiella Pneumonia, Yuanzhang Zheng

Dissertations

Increasing number of genes encoding PLP-dependent transcription regulators, MocR/GabR type regulators, have been identified in various bacterial genomes. However, only a handful of them, including MocR, PdxR and GabR have been studied experimentally. They control different aspects of the bacterial metabolism. Only GabR has reported crystallographic structures. MocR/GabR regulators possess a chimeric structure consisted of a WHTH DNA binding domain and an Aminotransferase-like regulation domain, which can bind PLP as an effector in transcription regulation. Such a chimeric construct presents an interesting case in molecular evolution. The regulation domains of All MocR/GabR type regulators loss their catalytic capacity during evolution …

An Evaluation Of The Information Security Awareness Of University Students, Alan Pike

Dissertations

Between January 2017 and March 2018, it is estimated that more than 1.9 billion personal and sensitive data records were compromised online. The average cost of a data breach in 2018 was reported to be in the region of US$3.62 million. These figures alone highlight the need for computer users to have a high level of information security awareness (ISA). This research was conducted to establish the ISA of students in a university. There were three aspects to this piece of research. The first was to review and analyse the security habits of students in terms of their own personal …

Game Types, Game-Related Behaviors And Resilience: Creating A Roadmap For Effective Gamification Design In Higher Education, Patrick Marino

Dissertations

Gamification, or the use of game-based mechanics and thinking in real world applications, is on the rise in educational environments. While various applications seek to increase engagement and motivation for tasks related to student success, research regarding best practices for the design of such systems is lacking. In fact, conflicting outcomes from various gamification studies at the secondary and tertiary education levels suggest that not all gamification designs are effective for increasing student success. Meanwhile, research from the medical field indicates gamification can be used to increase resilience; which has been linked to various student success outcomes including academic performance. …

Angels And Sub-Divine Supernatural Beings: Their Characteristics, Function, And Relationship To God And Humanity In Deuteronomy-Kings, Joni Amanda Mcguire-Moushon

Dissertations

This research analyzes selected passages in Deuteronomy-Kings in order to determine the characteristics and roles of supernatural sub-divine beings within these books. Then this data is compared with the angelology of the Second Temple period in order to identify the similarities and the extent of the differences between them.

Deuteronomy contains references to supernatural sub-divine beings, such as “demons” and “holy one(s)”. While Deuteronomy affirms the existence of sub-divine beings, it forbids the Israelites to worship them. In the books of Joshua and Judges, there is awareness of supernatural beings and their roles as warriors, messengers, and tormentors. However, in …

Islam, Christianity, Traditional Religions And Power Politics In Northern Nigeria Since Pre-Islamic Period, Emmanuel M. Abar

Dissertations

Problem

Currently in Northern Nigeria, religious interaction among the three major religious traditions, Islam, Christianity, and African Traditional Religion, is marred by violent religious conflicts. Also, competing concepts of religious legitimacy, which appeal to the historical heritage of Nigeria, are often used to validate and justify the violation of religious freedom. Does the current state of religious interaction among the various religious groups reflect the true heritage of religious interaction in Northern Nigeria? Or is it possible that the history of the interaction between African Traditional Religions, Islam, and Christianity in the past might actually be a heritage that points …

Ceramic Architectural Models From The Madaba Plains Region: A Selected Art Historical Analysis, Stefanie P. Elkins

Dissertations

Problem

Architectural models can be described as small, ceramic, house-shaped structures that come in an often bewildering array of shapes and sizes. They appear all over the ancient Near East, and although evidence shows that they were created as early as the Neolithic period, they seem to have peaked in popularity and proliferation during the Iron Age. A few studies and several typologies have been offered over the years, but none have addressed iconography or artistic motifs as well as shape. Furthermore, no in-depth typology of architectural models within the country of Jordan has been offered. This dissertation explores the …

Adventist Healthcare: A Qualitative Study Of 19th Century Founding Governing Principles In 21st Century Adventist Hospitals, Cesiah Yareth Pimentel Melendez

Dissertations

Problem and Purpose

Founding values and principles can help organizations stay focused on fulfilling their mission. This is especially true in faith-based organizations that seek to continue their founding principles as a governing commitment to their core identity. This study identified Adventist healthcare founding principles in Ellen G. White's early health visions and explored how Adventist healthcare leaders perceived these principles as governing principles applied to current Adventist healthcare practices.

Conceptual Framework and Research Design

Two metaphors and three areas of literature review guided my approach of this qualitative study of Adventist healthcare founding principles. My first metaphor of DNA …

Functionalized Carbon Nanotubes In Hydrophobic Drug Delivery, Kun Chen

Dissertations

The direct incorporation of carboxylated carbon nanotubes (f-CNTs) into hydrophobic drug particles during their formation via anti-solvent precipitation is presented. The approach is tested using two drugs namely antifungal agent Griseofulvin (GF) and antibiotic Sulfamethoxazole (SMZ) that have very different aqueous solubility. It is observed that the f-CNTs dispersed in the water serve as nucleating sites for crystallization and are readily incorporated into the drug particles without altering crystal structure or other properties. The results show that the hydrophilic f-CNTs dramatically enhance dissolution rate for both drugs. The increased degree of functionalization leads to higher hydrophilicity and therefore faster dissolution …

Cardiac Regenerative Medicine: Insights From Healthy And Diseased Engineered Tissues, Pamela Grace Hitscherich

Dissertations

Cardiovascular disease remains the leading cause of mortality in the United States. Current tissue engineering approaches have fallen short of promoting fully functional cardiovascular cells and the post-myocardial infarction microenvironment is still not well understood. These gaps in knowledge are addressed in this dissertation through the development of in vitro engineered cardiac tissues using electroactive materials to enhance the differentiation of pluripotent stem cell derived cardiomyocytes and through the development of in vitro myocardial inflammation models dedicated to understanding cardiomyocytes and macrophages interactions.

Specifically, piezoelectric poly (vinylidene fluoride-trifluoroethylene) (PVDF-TrFE) supports the attachment and survival of mouse embryonic stem cell derived …

Diffusion, Adoption, And Network Constraint: Can Understanding Personal Networks Of Afghan Women Improve The Adoption 0f Agricultural Innovations, Clair Wilcox

Dissertations

A plethora of case studies conducted in myriad locations find that factors influencing the adoption of agricultural innovation are different, emphasizing the need for locality specific understanding (Waddingon 2014). The diffusion of agricultural innovations may be influenced by the structure of the social system in which that diffusion is taking place. This study investigates the social structure of rural Afghan women, in an effort to determine how they interact and exchange information, and how the personal network structure, and the nature of the women’s interaction influences adoption of innovations. With the objective of framing rural development programs targeting women in …

Identifying Barriers To Teacher Implementation Of Evidence-Based Practices In Middle-School Reading, Brenda Fortson

Dissertations

This study explores factors that may be related to Mississippi’s 2015 eighth-grade reading scores, which rank the state in 50^th place (Nation’s Report Card, 2016). Whereas there are likely several factors that contribute to middle-school students’ poor performance on the high-stakes tests, this study examines teachers’ reported knowledge and use of evidence-based teaching practices, sense of self-efficacy in implementing the practices, and concerns regarding high-stakes testing and possible relationship with their implementation of the practices.

All public schools in Mississippi were invited to participate in an online survey of sixth-, seventh-, and eighth-grade teachers. After data were screened, 187 …

“The Moral Of This Nazi Fairytale”: A Qualitative Content Analysis Of Invisible Adult Education In World War Ii-Era Film, Lauren Carson

Dissertations

When the United States entered WWII, the government contracted with several film studios to produce propagandistic cartoons, newsreels, and short films. These contracts continued throughout the war, and government agencies not only censored these films, but also produced some of their own film media. The deliberately embedded messages planted to influence viewers worked well for several reasons. During the war years, the Nazi Party produced its own propaganda films, and while the United States decried that deliberate attempt to influence populations, the United States government was doing exactly what they condemned: producing film made to influence its own population. Since …

Hydrogen Bond Mediated Water Structuring, Diffusion, And Elastic Properties In Acrylamide Copolymer Glycohydrogels, April Levu Fogel

Dissertations

Glycohydrogels have recently gained considerable interest as biocompatible and high water content hydrogels that have similar physicochemical nature to the cell membrane, making them ideal materials for targeted biomedical and personal care applications (e.g., drug delivery systems, biosensors, and contact lenses). Regardless of the specific application, water-polymer and water-water hydrogen bonding interactions have been shown to dictate hydration stability and diffusional properties in traditional hydrogel architectures (e.g., crosslinked HEMA). However, due to the development of glycohydrogel materials within the past two decades, most literature focuses on synthetic techniques and general hydration characteristics. Furthermore, scant literature examines the effect of hydrophobically …

Documentary Production As A Site Of Struggle: State, Capital, And Precarity In The Contemporary Chinese Documentary, Jiachun Hong

Dissertations

Documentary filmmakers have been considered artists, authors, or intellectuals, but rarely as labor. This study investigates how the nature of work as well as life is changing for those who work in the expanding area of TV documentary in China, in the midst of China’s shift towards a market-based economy. How do documentary makers reconcile their passion for documentary making with the increasingly precarious conditions of work? And, how do they cope with and resist the pressures of neoliberalism to survive in increasingly competitive local and global markets? Based on data gathered through the interviews with 40 practitioners from January …

Analysis Of The Cis-Regulatory Element Lexicon In Upstream Gene Promoters Of Arabidopsis Thaliana And Oryza Sativa, Belan Khalil

Dissertations

AN ABSTRACT OF THE DISSERTATION OF BELAN M. KHALIL, for the Doctor of Philosophy degree in Plant Biology, presented July 11, 2018, at Southern Illinois University Carbondale. TITLE: ANALYSIS OF THE CIS-REGULATORY ELEMENT LEXICON IN UPSTREAM GENE PROMOTERS OF ARABIDOPSIS THALIANA AND ORYZA SATIVA. MAJOR PROFESSOR: Dr Matt Geisler Gene expression in plants is partly regulated through an interaction of trans-acting factors with the promoter regions of the gene. Trans-acting factor binding sites consist of short nucleotide sequences most often present in the upstream promoter region. These binding sites, the cis-regulatory elements (CREs), vary in structure, complexity and function. In …