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การศึกษาเปรียบเทียบกระบวนการสร้างความเป็นกลางทางการเมืองในข้าราชการพลเรือนฝ่ายประจำ ระหว่างประเทศไทย สหราชอาณาจักรและสหรัฐอเมริกา, ธีรพล บุญนาค
Chulalongkorn University Theses and Dissertations (Chula ETD)
การศึกษานี้มีวัตถุประสงค์เพื่อศึกษาความเหมือนและแตกต่างของกระบวนการสร้างความเป็นกลางทางการเมืองในข้าราชการพลเรือนฝ่ายประจำระหว่างประเทศไทย สหราชอาณาจักรและสหรัฐอเมริกา โดยเป็นการวิจัยเชิงคุณภาพ ดำเนินการผ่านการค้นคว้าเอกสาร ประกอบกับการสัมภาษณ์เชิงลึกผู้เกี่ยวข้องกับงานทรัพยากรบุคคลของประเทศไทย และเจ้าหน้าที่ของสถานทูตสหราชอาณาจักรและสหรัฐอเมริกาประจำประเทศไทย ผลการศึกษาพบว่า กฎหมายว่าด้วยข้าราชการพลเรือนของทั้งสามประเทศสามารถแสดงออกถึงความเข้าใจของรัฐต่อคำว่าเป็นกลางทางการเมือง ซึ่งทั้งสามประเทศมีความเข้าใจนิยามความเป็นกลางทางการเมืองตรงกัน โดยสหราชอาณาจักรและสหรัฐอเมริกาให้ความสำคัญกับการอบรมและจัดทำคู่มือการปฏิบัติตนอย่างเป็นกลางทางการเมืองให้แก่ข้าราชการพลเรือนฝ่ายประจำ แต่ประเทศไทยไม่ได้มีการบังคับให้ส่วนราชการจัดอบรมและจัดทำคู่มือในประเด็นนี้ ด้านการลงโทษข้าราชการที่ปฏิบัติตนไม่เป็นกลางทางการเมือง สหราชอาณาจักรและสหรัฐอเมริกาจัดให้มีเจ้าหน้าที่และหน่วยงานตรวจสอบความประพฤติข้าราชการ และมีคณะกรรมการสอบสวนข้อเท็จจริง ซึ่งหากพบความผิดสามารถลงโทษข้าราชการได้ทันที แต่ประเทศไทยไม่มีความจริงจัง ในเรื่องการตรวจสอบความประพฤติที่อาจไม่เป็นกลางทางการเมืองของข้าราชการ ทำให้ไม่มีการลงโทษให้เป็นแบบอย่างแก่ข้าราชการคนอื่น ๆ กฎหมายว่าด้วยความเป็นกลางและมารยาท ทางการเมืองของประเทศไทยจึงไม่มีสภาพบังคับในทางปฏิบัติ ดังนั้น หน่วยงานกลางด้านทรัพยากรบุคคลของประเทศไทยควรจัดให้มีการตรวจสอบและไต่สวนหาข้อเท็จจริงเกี่ยวกับ การปฏิบัติตนอย่างเป็นกลางทางการเมือง เพื่อรักษาผลประโยชน์และความน่าเชื่อถือของรัฐบาล ซึ่งเป็นปัจจัยสำคัญที่จะนำไปสู่ประสิทธิภาพและเสถียรภาพของรัฐบาลต่อไป
Biomarker Identification Of Pancreatic Ductal Adenocarcinoma Metastasis By Systems Biology Approach, Tanakamol Mahawan
Biomarker Identification Of Pancreatic Ductal Adenocarcinoma Metastasis By Systems Biology Approach, Tanakamol Mahawan
Chulalongkorn University Theses and Dissertations (Chula ETD)
Systems biology synergises biology with computational sciences, offering a holistic perspective and cutting-edge tools like machine learning (ML) to reveal disease biomarkers. ML can identify key molecular signals from omics data for biomarker candidate discovery. Effective ML demands practices avoiding data leakage and enhancing reproducibility. This study aimed to build a robust pipeline for biomarker candidates discovery using ML and applied it to pancreatic ductal adenocarcinoma (PDAC). PDAC is an aggressive pancreatic cancer with a poor prognosis. Over 80% of patients are diagnosed at late metastatic stages with no standard markers known for rapid and cost-effective metastasis diagnosis. Biomarkers for …
The Comparison Between Alternative And Standard Methods For Quality Control Of Diphtheria Toxoid In Thai-Gpo’S Dtp And Dt Vaccines (Adsorbed), Wanlop Leeden
Chulalongkorn University Theses and Dissertations (Chula ETD)
In response to the country's vaccine security policy and to make Thailand self-reliant in vaccine supply, the Government Pharmaceutical Organization has been successfully established he the production process of dT and DTP vaccine (Adsorbed). According to WHO recommendation, the quality control scheme for dT, DTP vaccines (adsorbed) includes identity test, toxicity and reversion to toxicity test, potency test, and antigen content and degree of absorption. Therefore, it is of interest to study and develop appropriate methods for use in quality control and for inclusion in the product registration application process. The comparison study of the quality testing methods can categorized …
Investigation Of Alpha Kinase 3 (Alpk3)-Associated Cardiomyopathy Using Multiomics And An Induced Pluripotent Stem Cell (Ipsc)-Derived Cardiomyocyte And Cardiac Organoid Model, Chanatjit Cheawsamoot
Investigation Of Alpha Kinase 3 (Alpk3)-Associated Cardiomyopathy Using Multiomics And An Induced Pluripotent Stem Cell (Ipsc)-Derived Cardiomyocyte And Cardiac Organoid Model, Chanatjit Cheawsamoot
Chulalongkorn University Theses and Dissertations (Chula ETD)
Hypertrophic cardiomyopathy and dilated cardiomyopathy together make up one of the highest prevalence genetic diseases in the world, estimated to have a prevalence of around 1 in 200 to 1 in 600 individuals. Most of the genes implicated in causing cardiomyopathy are those that encode sarcomeric components in cardiomyocytes, such as MYBPC3 and MYH7. Numerous genes that encode non-sarcomeric proteins or have unknown function have been increasingly associated with cardiomyopathy and it was thought that the resulting disease from variants in these genes tend to be mild and low penetrant. However, recent evidence of one of these unknown protein coding …
Washback Effects Of Vstep.3-5 On Lecturers' Teaching Practices And Students' Learning Strategies At Tertiary Level In Vietnam, Phuong Ai Ngoc Doan
Washback Effects Of Vstep.3-5 On Lecturers' Teaching Practices And Students' Learning Strategies At Tertiary Level In Vietnam, Phuong Ai Ngoc Doan
Chulalongkorn University Theses and Dissertations (Chula ETD)
The study aimed to explore the washback effects of “Vietnamese Standardized Test of English Proficiency” (VSTEP.3-5) - a locally produced high-stakes test that fulfills the country’s specific requirements – on Vietnamese EFL lecturers’ teaching practices and undergraduate students’ learning strategies. The study utilized a mixed-method design, incorporating three primary research instruments: questionnaires, semi-structured interviews, and classroom observation. Quantitative data were obtained through questionnaires delivered to 25 lecturers of English and 600 sophomores, Academic year 2022, at Hue University of Foreign Languages and International Studies (HUFLIS), Hue City, Central Vietnam. Qualitative data were collected thanks to in-depth interviews with 8 selected …
Effects Of Augmented Reality Hotel Situated-Learning Board Game On English Oral Communication Skills And Motivation Of Thai Efl Learners, Wipada Sutthiroj
Effects Of Augmented Reality Hotel Situated-Learning Board Game On English Oral Communication Skills And Motivation Of Thai Efl Learners, Wipada Sutthiroj
Chulalongkorn University Theses and Dissertations (Chula ETD)
The purpose of the study was (1) to study the effects of Augmented Reality Hotel Situated-learning Board Game on Thai EFL learners' oral communication skills, (2) to study the effects of Augmented Reality Hotel Situated-learning Board Game on Thai EFL learners' motivation, and (3) to explore the perceptions of Thai EFL learners towards Augmented Reality Hotel Situated-learning Board Game. The study's participant group comprises 25 diverse mixes of students from Rajamangala University of Technology Krungthep. The study employed a quasi-experimental design that used both qualitative and quantitative methods. The findings indicated that: (1) there was a significant improvement in the …
Bezlotoxumab Binding Specificity To Toxin B Of Clostridium Difficile, Kun Karnchanapandh
Bezlotoxumab Binding Specificity To Toxin B Of Clostridium Difficile, Kun Karnchanapandh
Chulalongkorn University Theses and Dissertations (Chula ETD)
Clostridioides difficile infection (CDI) is one of the significant global health issues. Toxin B is the main target protein preventing CDI recurrence. Clinical research has shown that bezlotoxumab (Bez), a monoclonal antibody designed to prevent CDI recurrences, is less effective against the B2 strain compared to the B1 strain, resulting in a high recurrence rate. Bez functions by binding to the epitope 1 and 2 regions in the combined repetitive oligopeptide (CROP) domain. Some binding residues are distinctively different between B1 and B2 strains. In this work, our goal was to understand and compare the interaction of toxins B1 and …
การวิเคราะห์โครงข่ายสำหรับแผนที่ทรัพยากรเพื่อการตอบโต้เหตุอัคคีภัย กรณีศึกษาเขตพระโขนง, กัญจณ์ หริ่งรอด
การวิเคราะห์โครงข่ายสำหรับแผนที่ทรัพยากรเพื่อการตอบโต้เหตุอัคคีภัย กรณีศึกษาเขตพระโขนง, กัญจณ์ หริ่งรอด
Chulalongkorn University Theses and Dissertations (Chula ETD)
การศึกษาในครั้งนี้มีวัตถุประสงค์เพื่อวิเคราะห์โครงข่ายการกระจายทรัพยากรด้านการตอบสนองต่อเหตุฉุกเฉินประเภทอัคคีภัย โดยพิจารณาศักยภาพเชิงพื้นที่ต่อการปฏิบัติการระงับเหตุอัคคีภัยในขอบเขตพื้นที่ เขตพระโขนง กรุงเทพมหานคร โดยนำข้อมูลเชิงพื้นที่ (spatial data) ตำแหน่งของทรัพยากรในการจัดการอัคคีภัย ความหนาแน่นของประชากร และสถิติตำแหน่งการเกิดเหตุอัคคีภัยระหว่างปี พ.ศ. 2563-2566 มาวิเคราะห์ความสัมพันธ์ระหว่างระยะทางและเวลาที่ใช้ในการเผชิญเหตุ (response time) โดยใช้เทคโนโลยีภูมิสารสนเทศ (GIS) แสดงการวิเคราะห์โครงข่าย (Network Analysis) ด้วยข้อมูลแบบเปิด (Open Data) ผ่านการนำเสนอแผนที่แบบเซลล์หกเหลี่ยม (Hexagonal Cell) เพื่อศักยภาพในการเผชิญเหตุอัคคีภัย และเสนอแนวทางการกระจายทรัพยากรด้านการจัดการระงับอัคคีภัยอย่างมีประสิทธิภาพยิ่งขึ้น เนื่องจากเขตพระโขนง กรุงเทพมหานคร มีพื้นที่ 13,576,720 ตารางเมตร สามารถแบ่งเป็นแผนที่รูปแบบเซลล์หกเหลี่ยมขนาดเส้นผ่านศูนย์กลาง 100 ม. ได้ 1,675 เซลล์ ผลการวิเคราะห์เบื้องต้นชี้ให้เห็นว่า ภูมิศาสตร์ของการวางทรัพยากรในการควบคุมอัคคีภัย โดยเฉพาะสถานีดับเพลิง มีผลต่อศักยภาพในการควบคุมอัคคีภัย ตำแหน่งของทรัพยากรในการเผชิญเหตุอัคคีภัยซึ่งกระจายอยู่ในทิศ เหนือ ตะวันออก และตะวันตก ช่วยให้การเข้าถึงพื้นที่เกิดเหตุสามารถใช้เวลาที่สั้นที่สุดในการควบคุมอัคคีภัยได้ภายในมาตรฐานขั้นต่ำคือ 10 นาที อย่างไรก็ตามเมื่อพิจารณาระยะทาง อุปสรรคด้านการจราจร และโอกาสในการเกิดเหตุซึ่งขึ้นอยู่กับความหนาแน่นของจำนวนประชากรแล้ว สำนักป้องกันและบรรเทาสาธารณภัยเขตพระโขนง กรุงเทพมหานคร และหน่วยงานที่เกี่ยวข้อง ยังต้องการข้อมูลด้านสถิติของเวลาที่ใช้ในการเผชิญเหตุ (response time) ในแต่ละช่วงเวลา เพื่อนำไปพัฒนาระบบบริการการเผชิญเหตุอัคคีภัยที่สอดคล้องกับการปฏิบัติการในเวลาที่ต่างกันออกไปและพิจารณาการกระจายทรัพยากรให้ครอบคลุมในเขตพระโขนงเพื่อเป็นประโยชน์ต่อทั้งผู้ประสบภัยและผู้อยู่อาศัยต่อไป
Vietnam Economic Influence In Laos During 2002-2020, Chayapat Wareenil
Vietnam Economic Influence In Laos During 2002-2020, Chayapat Wareenil
Chulalongkorn University Theses and Dissertations (Chula ETD)
This thesis examines Vietnam’s role in the Lao economy from 2002 to 2020 to study how Vietnam plays an important role in the Lao economy in an era where economic tools are a tool to expand influence and make Vietnam have competitors such as China and Thailand in playing a role in Laos. This thesis uses “Interdependence Theory” as a tool for explaining the relationship between Vietnam and Laos. The study found that although Vietnam may not be the country that invests the most in Vietnam, but Vietnam still plays an important role in Lao economy. Vietnam’s role in the …
The Role Of Tica In Thailand's Technical Assistance To The Countries In Mekong Subregion, Sathavee Supakatisan
The Role Of Tica In Thailand's Technical Assistance To The Countries In Mekong Subregion, Sathavee Supakatisan
Chulalongkorn University Theses and Dissertations (Chula ETD)
Technical assistance had been one of Thai foreign policy tools since the very end of Cold War until recent time. The function of Thai technical assistance was to facilitate better cooperation with other countries especially neighboring in Mekong subregion for mutual benefits. During the late 1980s, Thailand utilized her experiences as a recipient country by giving technical and economic assistance via DTEC, an official aid reception agency, to Indochina and Myanmar in order to extend her good will towards these countries for the purpose of economic and political development within in the region. In 2003, Thailand declared herself as a …
Efficiency Of Mrna Vaccine Against House Dust Mite Allergy In Mouse Model, Chanatip Thanasarnthungcharoen
Efficiency Of Mrna Vaccine Against House Dust Mite Allergy In Mouse Model, Chanatip Thanasarnthungcharoen
Chulalongkorn University Theses and Dissertations (Chula ETD)
Through the capacity to mediate Th1-biased immune responses and the induction of neutralizing antibodies, the mRNA-lipid nanoparticle (LNP) platform could represent an innovative approach for shorter, safer, and more effective treatment of house dust mite (HDM) allergy. Our previous study showed that nucleoside-modified mRNA encoding recombinant forms of HDM allergens Der p 1 and Der p 2 (ProDer p 1 and Der p 2 K96A) and formulated with ionizable LNP, induced Th1-biased immune responses and potent specific blocking IgG responses, while being non-reactogenic in sensitized mice. This present study evaluated the immunotherapeutic efficacy of HDM-specific mRNA-LNP-based AIT in a mouse …
The Future Of Meat Substitutes For Sustainable Food System: Insights From Chinese Consumer Preference And Role Of Agenda Setting, Wenxuan Guo
Chulalongkorn University Theses and Dissertations (Chula ETD)
The future of meat substitutes for China's sustainable food system was examined in this dissertation. Influence of media agenda-setting, consumer perception, preferences, and experts' opinions towards sustainable meat systems were investigated by text mining, online questionnaire survey, and stakeholder in-depth interviews. Integration of the agenda-setting concerning meat substitutes with the 2022 Chinese government dietary policy and the influence of articles in mainstream news is recommended. The research findings contribute to bridging the gap between policy formulation, agenda-setting, and public perception and suggest that media provide information consistently with the national food policy and provide education and knowledge correctly and clearly. …
Comparative Study On Intergenerational Support Influencing The Elderly Decision To Work In China And South Korea, Ying Li
Chulalongkorn University Theses and Dissertations (Chula ETD)
Intergenerational support refers to financial support and emotional support between parents and children. In South Korea and China, intergenerational support is significant in family relationships. This study examines the impact of intergenerational support influencing the elderly decision to work through an empirical research approach using data from CHARLS (China Health and Retirement Longitudinal Study) and KLSoA (Korean Longitudinal Study of Aging). The Logit results showed that in South Korea, children’s financial support to parents and emotional communication between generations significantly impacted the elderly’s work choices. In China, the frequency of meetings between parents and children impacts the elderly’s work choices. …
Trendy Asian Desserts And Urban Youth Identity Creation: Comparing Young People's Cultural Practices And Social Media Activities In Singapore, Bangkok And Kuala Lumpur, Shangya Li
Chulalongkorn University Theses and Dissertations (Chula ETD)
Urban Southeast youth create a type of dessert-centered cultural capital based in their encounters with Asia-centered desserts in trendy urban cafes. They turn these encounters into digital products to share online. This helps them create a refined Asian cosmopolitan identity grounded in localized forms of food culture and history. This identity distinguishes them from earlier generations and situates themselves in a cosmopolitan middle class. The research examines young people’s onsite and online behaviors with four kinds of Asian desserts: Shibuya toast, Kakigori, Bingsu and Bubble tea in cafes and restaurants found in three cities – Singapore, Bangkok, and Kuala Lumpur. …
Exploring Communication Competence And The Attitudes Of Lower Secondary Efl Students Towards Communication Competence In An Online Project-Based Learning In Myanmar, Khaing Thar Tun
Chulalongkorn University Theses and Dissertations (Chula ETD)
This study explored communication competence, small-group communication competence, and the attitudes of lower secondary EFL students towards communication competence in an online project-based learning approach in Myanmar. The study used a mixed-methods research design that integrated surveys, semi-structured interviews, and observations. The study discovered that lower secondary EFL students' online communication competence was slightly high, approaching sufficing competence, while their small-group communication competence in online PBL learning settings was moderately high, approaching maximizing competence. The study predicted slightly high online communication competence and moderately high small-group communication competence within the parameters of the population. In addition, approximately 30% of lower …
Digital Sustainable Livelihoods And Displacement: A Study Of Myanmar Mixed Migrants In Mae Sot, Thailand, Thinn Nadi Soe
Digital Sustainable Livelihoods And Displacement: A Study Of Myanmar Mixed Migrants In Mae Sot, Thailand, Thinn Nadi Soe
Chulalongkorn University Theses and Dissertations (Chula ETD)
This study explores how digital tools enhance sustainable livelihoods for Myanmar mixed migrants in Thailand and examines how digital resources integrate into livelihood strategies for self-reliance and socio-economic well-being using a modified Sustainable Livelihood Framework. Insights from key informants’ experiences, and stakeholder perspectives reveal that mixed migrants leverage strong human and social capital, showing adaptability and resilience, which can lead to sustainable livelihoods with digital engagement. However, major challenges in financial stability, digital access, natural resources, and social inclusion require further support.
Consumer Protection In Asean's E-Commerce: Common Issues And The Path Towards Harmonization Of Regulatory Frameworks, Yi-Hsuan Tseng
Consumer Protection In Asean's E-Commerce: Common Issues And The Path Towards Harmonization Of Regulatory Frameworks, Yi-Hsuan Tseng
Chulalongkorn University Theses and Dissertations (Chula ETD)
The purpose of this study is to examine legal documents to identify disparities in consumer protection regulations in ASEAN's e-commerce and to propose recommendations to benefit from harmonization of regulatory framework. The study’s scope includes ASEAN’s six key internet economies: Indonesia, Malaysia, the Philippines, Singapore, Thailand, and Vietnam. Textual and comparative analyses of legal documents in the six ASEAN member countries reveal considerable variations in crucial issues in ASEAN’s consumer protection laws, potentially resulting in unequal protection levels for consumers from different ASEAN countries, where Singapore is the best practice. As a result, the study suggests that other ASEAN countries …
Migration Of Koreans To The Perm Region During The Korean Enlightenment Period, Luiza Veronika Kim-Istomina
Migration Of Koreans To The Perm Region During The Korean Enlightenment Period, Luiza Veronika Kim-Istomina
Chulalongkorn University Theses and Dissertations (Chula ETD)
The thesis analyzes the migration of Koreans to the Perm region during the Korean enlightenment period. To achieve this goal, the theory of segmental migration was chosen, a hermeneutic approach and discourse analysis were used to analyze archival sources, as well as statistical methods and a database to study the social status of migrants and a comparative method to identify the characteristics of migration. The study was carried out using sources from the Perm State Archive, 1904-1910. The thesis explains the reasons for the migration of Koreans to the Perm region, the social status and assimilation of migrants and the …
Chinese Language Education In Asean Confucius Institutes: Case Studies Of Universities In Thailand, Malaysia, And Singapore, Pengyu Lin
Chulalongkorn University Theses and Dissertations (Chula ETD)
This thesis will examine how Confucius Institutes in Bangkok, Kuala Lumpur, and Singapore use localized forms of Chinese language education to create richer opportunities for Chinese and ASEAN citizens to communicate. Using concepts from Chinese language education and Intercultural Communication Studies, the thesis will identify specific ways that Chinese language education has been adapted in Confucius Institute programs at Chulalongkorn University in Bangkok, University of Malaya in Kuala Lumpur, and Nanyang Technological University in Singapore to suit local cultural, social, and political contexts and to enhance intercultural dialogue. To analyze how the Chinese language teaching models used in Confucius Institutes …
Entrainment As A Therapeutic Mechanism In Music Therapy: A Scoping Review, Weiting Yuan
Entrainment As A Therapeutic Mechanism In Music Therapy: A Scoping Review, Weiting Yuan
Chulalongkorn University Theses and Dissertations (Chula ETD)
Entrainment is a fundamental concept in music therapy, illustrating the profound influence of environmental rhythms on internal biological processes. It plays a pivotal role in music therapy as one of the key mechanisms for therapeutic change. Due to the wide variability in existing literature on the implementation of entrainment in music therapy, this scoping review aimed to summarize existing studies and identify key characteristics and outcomes addressed in this literature. Out of the 167 items identified from the initial database search, a total of 10 studies were selected for review, revealing a diverse range of methodologies and participant demographics. Predominantly …
A Scoping Review Of Community Music Projects For Adolescents And Young Adults With Asd, Alicia Ng Wei Chen
A Scoping Review Of Community Music Projects For Adolescents And Young Adults With Asd, Alicia Ng Wei Chen
Chulalongkorn University Theses and Dissertations (Chula ETD)
Transition after graduation poses significant psychosocial challenges for adolescents with autism spectrum disorder (ASD), often exacerbated by the abrupt cessation of services and support programs. A potential intervention to address their needs is community music projects. This scoping review aims to summarize current practices, identify research gaps, and offer insights for music therapists, community leaders, and care providers by reviewing relevant literature on community music projects for adolescents and young adults with ASD. Out of 784 initially screened studies, 15 articles met the inclusion criteria. Studies were found to be predominantly conducted in the USA and utilized diverse research methodologies. …
Under The Queen’S Umbrella: The Representation Of Modern Korean Society Through Historical Korean Drama, Prichaya Thanayuwat
Under The Queen’S Umbrella: The Representation Of Modern Korean Society Through Historical Korean Drama, Prichaya Thanayuwat
Chulalongkorn University Theses and Dissertations (Chula ETD)
This research examines how the historical Korean drama "Under the Queen's Umbrella" (2022) portrays modern Korean society. By comparing the societal depictions within the drama with contemporary Korean society, it analyzes the benefits and drawbacks of using historical dramas to represent modern social issues. The researcher primarily uses Stuart Hall's theory of representation as a framework. The study found that the scriptwriter of the drama created a representation of modern Korean phenomena through a cross-temporal representation, highlighting the intense competition within the education system, the dynamics of parental and family institutions, and human rights issues. Moreover, Korean society as depicted …
การแสดงขับร้องเดี่ยวระดับมหาบัณฑิตโดย อิสรพงศ์ ดอกยอ, อิสรพงศ์ ดอกยอ
การแสดงขับร้องเดี่ยวระดับมหาบัณฑิตโดย อิสรพงศ์ ดอกยอ, อิสรพงศ์ ดอกยอ
Chulalongkorn University Theses and Dissertations (Chula ETD)
การแสดงขับร้องเดี่ยวระดับมหาบัณฑิตโดย อิสรพงศ์ ดอกยอ มีจุดประสงค์เพื่อนำเสนอและถ่ายทอดบทเพลงร้องศิลป์ บทเพลงพื้นบ้าน และบทเพลงลูกทุ่งไทยต่อสาธารณชน โดยการแสดงขับร้องเดี่ยวในครั้งนี้ผู้วิจัยได้คัดเลือกบทเพลงรวมทั้งสิ้น 11 เพลง แบ่งออกเป็น 3 ประเภทดังนี้ 1) บทเพลงร้องศิลป์ จำนวน 2 เพลง 2) บทเพลงพื้นบ้านภาษาอังกฤษ จำนวน 3 เพลง และ 3) บทเพลงลูกทุ่งไทยในหลายยุคที่มีความเป็นเอกลักษณ์ของไทยอย่างชัดเจน จำนวน 6 เพลง ผู้วิจัยได้ศึกษาค้นคว้าเกี่ยวกับประวัติความเป็นมาและได้วิเคราะห์บทเพลง อย่างละเอียด เพื่อนำมาตีความหมายและนำไปสู่การศึกษาและสังเคราะห์เป็นวิธีการขับร้อง ที่เหมาะสมกับบทเพลงในแต่ละประเภทโดยมุ่งประเด็นไปที่การศึกษาเกี่ยวกับเทคนิคการขับร้อง ในบทเพลงร้องศิลป์และบทเพลงพื้นบ้านภาษาอังกฤษ เพื่อเป็นแนวทางในการต่อยอดและประยุกต์ กับการขับร้องบทเพลงลูกทุ่งไทยในรูปแบบการนำเสนอที่มีเอกลักษณ์เฉพาะตัวและเหมาะสม กับการจัดแสดงในยุคปัจจุบัน
Measurement Of Precipitated Calcium Citrate In Urine By Murexide-Based Indicator Displacement Assay And Its Clinical Utility In Calcium Oxalate Urolithiasis, Chaiyadol Tantasith
Measurement Of Precipitated Calcium Citrate In Urine By Murexide-Based Indicator Displacement Assay And Its Clinical Utility In Calcium Oxalate Urolithiasis, Chaiyadol Tantasith
Chulalongkorn University Theses and Dissertations (Chula ETD)
Urinary stone, mainly composed of calcium oxalate (CaOx), is a longstanding urologic condition with high prevalence and recurrence rates. Dietary habits, specifically increased consumption of high oxalate diet and low intake of citrate-containing foods, lead to hyperoxaluria and hypocitraturia that directly contribute to CaOx stone formation. Measurements of urinary oxalate and citrate are essential to estimate the risk of CaOx stone formation. Currently, high-performance liquid chromatography is used for urinary citrate measurement, but it is complicated and requires well-trained technicians. We hypothesized that instead of directly measuring citrate in urine, measurement of calcium citrate (CalCit) precipitated in urine challenging with …
Development Of Raman Spectroscopy-Integrated Calcium Oxalate Crystallization Index (Rcoci) Test And Its Clinical Validation For Diagnosing Calcium Oxalate Urolithiasis, Kamonchat Boonkam
Development Of Raman Spectroscopy-Integrated Calcium Oxalate Crystallization Index (Rcoci) Test And Its Clinical Validation For Diagnosing Calcium Oxalate Urolithiasis, Kamonchat Boonkam
Chulalongkorn University Theses and Dissertations (Chula ETD)
Urinary stone disease is mostly formed in the kidney and is highly recurrent. The most common type of urinary stones is calcium oxalate (CaOx). The development of urinary screening tests for estimating risk of CaOx stone formation is still challenging. Recently, we developed a urinary test, called indole-reacted calcium oxalate crystallization index (iCOCI) test, that provided a high diagnostic accuracy for CaOx urolithiasis. However, the iCOCI test is time-consuming and highly acidic chemicals are required for quantifying amount of CaOx. In this study, we proposed to develop a new method, called Raman spectroscopy-integrated calcium oxalate crystallization index (rCOCI) test, that …
The Combination Effect Of Lapatinib And Palbociclib In Endocrine-Resistant Breast Cancer Cells, Kantasorn Horpratraporn
The Combination Effect Of Lapatinib And Palbociclib In Endocrine-Resistant Breast Cancer Cells, Kantasorn Horpratraporn
Chulalongkorn University Theses and Dissertations (Chula ETD)
Hormonal therapy is necessary in hormone receptor-positive breast cancer patients. It is used in both early and advanced-stage patients. Unfortunately, many patients developed endocrine resistance later on after the treatment was initiated and this could progress the disease. Endocrine resistance results from many mechanisms, including HER2 signaling pathway. These resistant breast cancer cells exhibit more HER2 signaling proteins such as AKT and ERK, compared to wild-type hormone receptor-positive breast cancer cells. Palbociclib is a CDK4/6 inhibitor and is indicated in patients who developed tamoxifen resistance. Lapatinib is a dual tyrosine kinase inhibitor- HER1 and HER2 and is used in HER2-overexpressed …
Epigenetic Regulation Of Leucine Rich Repeat Containing G Protein Coupled Receptor 5 (Lgr5) In Corneal Endothelial Cells, Kulsiri Prakanrattana
Epigenetic Regulation Of Leucine Rich Repeat Containing G Protein Coupled Receptor 5 (Lgr5) In Corneal Endothelial Cells, Kulsiri Prakanrattana
Chulalongkorn University Theses and Dissertations (Chula ETD)
Human corneal endothelial cells (hCECs) are vital for maintaining corneal transparency. However, their limited capacity for proliferation can result in vision loss, requiring corneal transplantation. The Leucine-rich repeat-containing G protein-coupled receptor 5 (LGR5) plays a critical role in maintaining various fetal and adult stem cell types by promoting the Wnt/β-catenin signaling. Although LGR5 is present in corneal endothelial progenitors, its expression decreases as these cells mature, coinciding with the loss of replicative properties. In this study, we explore strategies to reactivate LGR5 expression in cultured hCECs through epigenetic modulation. We found low levels of DNA methylation and hydroxymethylation at LGR5 …
Crispr-Cas12a-Based Detection And Differentiation Of Mycobacterium Spp., Peeraphan Compiro
Crispr-Cas12a-Based Detection And Differentiation Of Mycobacterium Spp., Peeraphan Compiro
Chulalongkorn University Theses and Dissertations (Chula ETD)
Mycobacterium species cause several vital human diseases, including tuberculosis (TB) and non-tuberculous mycobacterial (NTM) infections. TB is a chronic infectious disease caused by the Mycobacterium tuberculosis complex (MTBC). Additionally, non-tuberculous mycobacteria infections are caused by major NTM species, including Mycobacterium abscessus, Mycobacterium avium, Mycobacterium fortuitum, Mycobacterium kansasii, Mycobacterium gordonae, and Mycobacterium intracelulare, are medically necessary. Both groups of infections can lead to outbreaks in immunocompromised individuals and AIDS patients. It is crucial to differentiate between these two groups of mycobacterial infections, as they require distinct treatment approaches. However, initial diagnosis poses limitations in terms of time and diagnostic tools. Therefore, …
Functional Studies Of P.N258k And P.G279d Variants In The Kcnq2 Gene, Suphalak Chokvithaya
Functional Studies Of P.N258k And P.G279d Variants In The Kcnq2 Gene, Suphalak Chokvithaya
Chulalongkorn University Theses and Dissertations (Chula ETD)
Mutations in the KCNQ2 gene encoding for voltage-gated K channel subunits underlying the neuronal M-current, have been associated with infantile-onset epileptic disorders. The clinical spectrum ranges from self-limited neonatal seizures to epileptic encephalopathy and delayed development. Although gain- and loss-of-function mutations of KCNQ2 leads to indistinguishable phenotypes, different therapeutic approaches are required. To better understand genotype-phenotype correlation, more reports of patients and their mutations with elucidated molecular mechanism are needed. Here, we report nine unrelated patients with KCNQ2-related epilepsy carrying de novo heterozygous KCNQ2 p.N258K or p.G279D identified via Trio exome sequencing that has never been previously reported. To investigates …
The Effect Of Water Temperature And Carbohydrate Drink On Intestinal Epithelial Injury, Endotoxemia, Splanchnic Perfusion, And Core Temperature, During Running In The Heat, Warot Rangsimahariwong
The Effect Of Water Temperature And Carbohydrate Drink On Intestinal Epithelial Injury, Endotoxemia, Splanchnic Perfusion, And Core Temperature, During Running In The Heat, Warot Rangsimahariwong
Chulalongkorn University Theses and Dissertations (Chula ETD)
Background: Prolonged exercise can result in splanchnic hypoperfusion and elevated core body temperature (Tcore), which can contribute to gastrointestinal injury and endotoxemia. The effects of fluid temperature and carbohydrate consumption during exercise on these variables are less clear. Objectives: The study aimed to determine the effects of the temperature of water and carbohydrate drinks on intestinal epithelial injury, endotoxemia, splanchnic perfusion, and Tcore during 60-minute of moderate-intensity running. Methods: Ten participants completed four 60-minute running trials at 70% VO2max with different types of hydration: no water (NW), ambient temperature water (ATW), cold water (CW), and cold carbohydrate water (CW+CHO). Doppler …