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Articles 6001 - 6030 of 20106

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What We Think, What We Know And What We Think We Know About False Convictions, Samuel Gross Jan 2017

What We Think, What We Know And What We Think We Know About False Convictions, Samuel Gross

Articles

False convictions are notoriously difficult to study because they can neither be observed when they occur nor identified after the fact by any plausible research strategy. Our best shot is to collect data on those that come to light in legal proceedings that result in the exoneration of the convicted defendants. In May 2012, the National Registry of Exonerations released its first report, covering 873 exonerations from January 1989 through February 2012. By October 15, 2016, we had added 1,027 cases: 599 exonerations since March 1, 2012, and 428 that had already happened when we issued our initial report but …


Tax Treatment Of A Marijuana Business, Douglas A. Kahn, Howard Bromberg Jan 2017

Tax Treatment Of A Marijuana Business, Douglas A. Kahn, Howard Bromberg

Articles

Currently, twenty-eight states and the District of Columbia allow the use of marijuana for medical purposes and permit the conduct of a business marketing of marijuana for that purpose. Eight of those states and the District of Columbia permit the recreational use of marijuana. There is reason to believe that more states will decriminalize the marketing of marijuana. However, marijuana is listed in Schedule 1 of the federal Controlled Substances Act of 1970 (CSA) which makes it illegal under federal law to manufacture or distribute marijuana even when it is legal to do so under local state law. In a …


Labor And Employment Arbitration Today: Mid-Life Crisis Or New Golden Age?, Theodore J. St. Antonie Jan 2017

Labor And Employment Arbitration Today: Mid-Life Crisis Or New Golden Age?, Theodore J. St. Antonie

Articles

The major developments in employer-employee arbitration currently do not involve labor arbitration, that is, arbitration between employers and unions. The focus is on employment arbitration, arbitration between employers and individual employees. Beginning around 1980, nearly all the states judicially modified the standard American doctrine of employment-at-will whereby, absent a statutory or contractual prohibition, an employer could fire an employee "for good cause, for no cause, or even for cause morally wrong." Under the new regime, grounded in expansive contract and public policy theories, wrongfully discharged employees often reaped bonanzas in court suits, with California jury awards averaging around $425,000." Many …


Equality Adds Quality: On Upgrading Higher Education And Research In The Field Of Law, Susanne Baer Jan 2017

Equality Adds Quality: On Upgrading Higher Education And Research In The Field Of Law, Susanne Baer

Articles

Much has been attempted, and many pro1ects are still underway aimed at achieving equality in higher education and research. Today, the key argument to demand and support the integration of gender in academia is that equality is indeed about the quality on which academic work is supposed to be based. Although more or less national political, social and cultural contexts matter as much as academic environments, regarding higher education and research, the integration of gender into the field of law seems particularly interesting. Faculties of law enjoy a certain standing and status, are closely connected to power and politics, and …


A Geo-Statistical Investigation Of Agricultural And Infrastructural Risk Factors Associated With Primary Verotoxigenic E. Coli (Vtec) Infection In The Republic Of Ireland, 2008–2013, Paul Hynds, Jean O'Dwyer, Una B. Fallon, Coilín Oscar Óhaiseadha Jan 2017

A Geo-Statistical Investigation Of Agricultural And Infrastructural Risk Factors Associated With Primary Verotoxigenic E. Coli (Vtec) Infection In The Republic Of Ireland, 2008–2013, Paul Hynds, Jean O'Dwyer, Una B. Fallon, Coilín Oscar Óhaiseadha

Articles

Ireland reports the highest incidence of verotoxigenic Escherichia coli (VTEC) infection in Europe. This study investigated potential risk factors for confirmed sporadic and outbreak primary VTEC infections during 2008-2013. Overall, 989 VTEC infections including 521 serogroup O157 and 233 serogroup O26 were geo-referenced to 931 of 18488 census enumeration areas. The geographical distribution of human population, livestock, unregulated groundwater sources, domestic wastewater treatment systems (DWWTS) and a deprivation index were examined relative to notification of VTEC events in 524 of 6242 rural areas. Multivariate modelling identified three spatially derived variables associated with VTEC notification: private well usage (odds ratio (OR) …


Raman Spectroscopic Analysis Of Oral Cells In The High Wavenumber Region, Fiona Lyng, Luis Felipe C.S Carvalho, Franck Bonnier, Cláudio Tellez, Laurita Dos Santos, Kate O´Callaghan, Jeff O'Sullivan, Luis Eduardo S. Soares, Hugh Byrne Jan 2017

Raman Spectroscopic Analysis Of Oral Cells In The High Wavenumber Region, Fiona Lyng, Luis Felipe C.S Carvalho, Franck Bonnier, Cláudio Tellez, Laurita Dos Santos, Kate O´Callaghan, Jeff O'Sullivan, Luis Eduardo S. Soares, Hugh Byrne

Articles

No abstract provided.


Correlation Between The Structure And The Anticorrosion Barrier Properties Of Hybrid Sol–Gel Coatings: Application To The Protection Of Aa2024-T3 Alloys, Maikki Cullen, Muhammad Morshed, Mary O'Sullivan, Emma Mchugh, Brendan Duffy, Mohamed Oubaha Jan 2017

Correlation Between The Structure And The Anticorrosion Barrier Properties Of Hybrid Sol–Gel Coatings: Application To The Protection Of Aa2024-T3 Alloys, Maikki Cullen, Muhammad Morshed, Mary O'Sullivan, Emma Mchugh, Brendan Duffy, Mohamed Oubaha

Articles

Hybrid sol–gel materials have been extensively studied as viable alternatives to toxic chromate (VI)-based coatings for the corrosion protection of AA2024-T3 in the aerospace industry, due to the wide range of available chemistries they offer and the tremendous development potential of innovative functional coatings. However, so far, little work has been performed in identifying the effect of the employed chemistries on the structure and anticorrosion properties of the coatings. This work proposes to contribute to a better understanding of the relationship existing between the structure, morphology and anticorrosion properties of hybrid sol–gel coatings deposited on AA2024- T3 aluminium surfaces, the …


An Insight Into The Superior Performance Of A Heterogeneous Gold Nanocatalyst Supported By A Single Walled Carbon Nanotubes Compared To Titanium Dioxide And Amorphous Carbon For The Green Aerobic Oxidation Of Aromatic Alcohols, Anne Shanahan, Mary Mcnamara, Hugh Byrne, James A. Sullivan Jan 2017

An Insight Into The Superior Performance Of A Heterogeneous Gold Nanocatalyst Supported By A Single Walled Carbon Nanotubes Compared To Titanium Dioxide And Amorphous Carbon For The Green Aerobic Oxidation Of Aromatic Alcohols, Anne Shanahan, Mary Mcnamara, Hugh Byrne, James A. Sullivan

Articles

Gold nanocomposites based on three supports, single wall carbon nanotubes, carbon black and TiO2, were prepared using an in-situ reduction technique and characterized. They were tested for their suitability as heterogeneous catalysts in the green aerobic oxidation of 1-phenylethanol, 2-phenylethanol and benzylalcohol of industrial importance. For all reactions, the use of single wall carbon nanotubes as supports resulted in superior reaction efficiency and specificity for aldehyde to that of TiO2 and carbon black. The gold nanocatalysts can be reused over several reaction cycles with a minimal degeneration in catalytic activity. The activity of the gold nanoparticle catalyst was related to …


Effects Of Cold Plasma On Surface, Thermal And Antimicrobial Release Properties Of Chitosan Film, Shashi Kishor Pankaj, Carmen Bueno-Ferrer, N.N. Misra, Luke O'Neill, Paula Bourke, P.J Cullen Jan 2017

Effects Of Cold Plasma On Surface, Thermal And Antimicrobial Release Properties Of Chitosan Film, Shashi Kishor Pankaj, Carmen Bueno-Ferrer, N.N. Misra, Luke O'Neill, Paula Bourke, P.J Cullen

Articles

This work aims to analyze the effects of cold atmospheric air plasma treatment of antimicrobial chitosan film with different levels of thymol. Optical characterization of the dielectric barrier discharge showed the generation of reactive nitrogen and oxygen species by the system. A significant increase in the surface roughness was observed after cold plasma treatment of the films. No significant difference was observed in the thermal profile of the plasma-treated films. A significant increase in the thymol diffusion coefficient was observed after the plasma treatment for all the active films.


Monitoring Player Fitness, Fatigue Status And Running Performance During An In-Season Training Camp In Elite Gaelic Football, Shane Malone, Brian Hughes, Mark Roe, Kieran Collins, Martin Buchheit Jan 2017

Monitoring Player Fitness, Fatigue Status And Running Performance During An In-Season Training Camp In Elite Gaelic Football, Shane Malone, Brian Hughes, Mark Roe, Kieran Collins, Martin Buchheit

Articles

Objectives: To examine selected perceptual and physiological measures to monitor fitness, fatigue and running performance during an in-season training camp in elite Gaelic football. Methods: Twenty-two elite Gaelic football players were monitored for training load, perceived ratings of wellness, heart rate variability (HRV; LnSD1), heart rate recovery (HRR), exercise heart rate (HRex), lower limb muscular power (CMJ) and global positioning system (GPS) variables. The Yo-Yo intermittent recovery test level 1 (Yo-YoIR1) was assessed pre and post the training camp. With specific small-sided games (SSG) used as a measure of running performance. Results: During the camp, HRex decreased (−12.2%), HRR increased …


Lost In Transplantation: The Supreme Court's Post-Prudence Jurisprudence, Adam N. Steinman Jan 2017

Lost In Transplantation: The Supreme Court's Post-Prudence Jurisprudence, Adam N. Steinman

Articles

This essay is an invited response to Fred Smiths Vanderbilt Law Review article Undemocratic Restraint Smith critiques an important trend in the Supreme Courts decisions on standing the transformation of concepts that had been viewed as judiciallycreated prudential limits on a partys standing to sue into concepts grounded in positive law such as federal statutes or the Constitution This essay uses two Supreme Court decisions which coincidentally came down weeks after Smiths article was published to highlight some questions and concerns regarding two areas of standing doctrine that Smith examines One subject of doctrinal transplantation has been the zone of …


Civilizing Criminal Settlements, Russell M. Gold, Carissa Byrne Hessick, F. Andrew Hessick Jan 2017

Civilizing Criminal Settlements, Russell M. Gold, Carissa Byrne Hessick, F. Andrew Hessick

Articles

No abstract provided.


The Cost Of Inexperience, Mirit Eyal-Cohen Jan 2017

The Cost Of Inexperience, Mirit Eyal-Cohen

Articles

Free market entry is vital in preventing concentration of market power and eliminating large deadweight losses Yet in recent years studies show that newcomers are less successful than existing firms that have diversifies their products in the market What might explain this phenomenonThis Article unveils a regulatory catch 22 It reveals that although a regulation may be efficient in correcting a certain market failure its distributional effects may create another It exposes the degree to which "economies of experience" in regulation create significant disadvantages to newcomers and provide substantial advantages to oldtimers Being wellversed in their marketplace oldtimers possess knowledge …


There's No Place Like Home: Reshaping Community Interventions And Policies To Eliminate Environmental Hazards And Improve Population Health For Low-Income And Minority Communities, Emily A. Benfer, Allyson E. Gold Jan 2017

There's No Place Like Home: Reshaping Community Interventions And Policies To Eliminate Environmental Hazards And Improve Population Health For Low-Income And Minority Communities, Emily A. Benfer, Allyson E. Gold

Articles

Substandard housing and environmental conditions threaten the health and wellbeing of individuals residing throughout the United States Empirical evidence on the relationship between housing and health has increased exponentially However despite the growth in research residents continue to be exposed to environmental health hazards Minorities and people in poverty are exposed to environmental health hazards at a disproportionately high rate Hazards such as lead mold pest infestation radon and carbon monoxide among others threaten individual safety and health and limit one's ability to access opportunity in society Moreover the effects of exposure can be farreaching Common approaches to healthy communities …


Design-Based Research Mobile Gaming For Learning Jewish History, Tikkun Olam, And Civics, Owen Gottlieb Jan 2017

Design-Based Research Mobile Gaming For Learning Jewish History, Tikkun Olam, And Civics, Owen Gottlieb

Articles

How can Design-Based Research (DBR) be used in the study of video games, religious literacy, and learning? DBR uses a variety of pragmatically selected mixed methods approaches to design learning interventions. Researchers, working with educators and learners, design and co-design learning artifacts and environments. They analyze those artifacts and environments as they are used by educators and learners, and then iterate based on mixed methods data analysis. DBR is suited for any "rich contextualized setting in which people have agency." (Hoadley 2013) such as formal or informal learning environments.

The case covered in this chapter is a mobile Augmented Reality …


Ethanol Extract Of Blighia Sapida Stem Bark Show Remarkable Prophylactic Activity In Experimental Plasmodium Berghei-Infected Mice., Olayinka O. Otegbade, Johnson A. Ojo, Dolapo I. Adefokun, Oyindamola O. Abiodun, Bolaji N. Thomas, Olusola Ojurongbe Jan 2017

Ethanol Extract Of Blighia Sapida Stem Bark Show Remarkable Prophylactic Activity In Experimental Plasmodium Berghei-Infected Mice., Olayinka O. Otegbade, Johnson A. Ojo, Dolapo I. Adefokun, Oyindamola O. Abiodun, Bolaji N. Thomas, Olusola Ojurongbe

Articles

This work explores the antiplasmodial potential of ethanol extract of Blighia sapida (Lin. Sapindaceae) in chloroquine (CQ)- resistant Plasmodium berghei (ANKA strain)–infected mice. Chloroquine-resistant (ANKA) strain of P berghei was inoculated intraperitoneally into Swiss albino mice. Mice were treated orally for 4 consecutive days, before and after inoculation (prophylactic, suppressive, and curative models) with graded doses of the plant extracts with Artemether-Lumefantrine (Coartem) as control. Prophylactically, the extract showed a remarkable activity in the chemosuppression of P berghei parasites (P


How Much Wind And Solar Are Needed To Realize Emissions Benefits From Storage?, Srujana Naga Goteti, Eric Hittinger, Eric Williams Jan 2017

How Much Wind And Solar Are Needed To Realize Emissions Benefits From Storage?, Srujana Naga Goteti, Eric Hittinger, Eric Williams

Articles

Environmental outcomes from energy storage depend on its usage patterns, the existing generation fleet, and fossil fuel prices. This work models the deployment of large, non-marginal quantities of energy storage and wind and solar power to determine their combined effects on grid system emissions. Two different grid environments are analyzed: a coal-heavy grid (Midcontinent ISO) and non-coal grid (New York ISO). An iterative dispatch model is used that operates storage to maximize income, considering that this operation can influence wholesale energy prices. With current low natural gas prices ($2.6 per MMBtu), adding storage slightly reduces carbon emissions in New York, …


To Be Or Not To Be T4: Evidence Of A Complex Evolutionary Pathway Of Head Structure And Assembly In Giant Salmonella Virus Spn3us, Bazla Ali, Maxim Desmond, Sara Mallory, Andrea Benitez, Larry J. Buckley, Susan T. Weintraub, Michael V. Osier, Lindsay W. Black, Julie A. Thomas Jan 2017

To Be Or Not To Be T4: Evidence Of A Complex Evolutionary Pathway Of Head Structure And Assembly In Giant Salmonella Virus Spn3us, Bazla Ali, Maxim Desmond, Sara Mallory, Andrea Benitez, Larry J. Buckley, Susan T. Weintraub, Michael V. Osier, Lindsay W. Black, Julie A. Thomas

Articles

Giant Salmonella phage SPN3US has a 240-kb dsDNA genome and a large complex virion composed of many proteins for which the functions of most are undefined. We recently determined that SPN3US shares a core set of genes with related giant phages and sequenced and characterized 18 amber mutants to facilitate its use as a genetic model system. Notably, SPN3US and related giant phages contain a bolus of ejection proteins within their heads, including a multi-subunit virion RNA polymerase (vRNAP), that enter the host cell with the DNA during infection. In this study, we characterized the SPN3US virion using mass spectrometry …


Magnetometry Via Spin-Mechanical Coupling In Levitated Optomechanics, Pardeep Kumar, Mishkatul Bhattacharya Jan 2017

Magnetometry Via Spin-Mechanical Coupling In Levitated Optomechanics, Pardeep Kumar, Mishkatul Bhattacharya

Articles

We analyze magnetometry using an optically levitated nanodiamond. We consider a configuration where a magnetic field gradient couples the mechanical oscillation of the diamond with its spin degree of freedom provided by a nitrogen vacancy center. First, we investigate the measurement of the position spectrum of the mechanical oscillator. We find that conditions of ultrahigh vacuum and feedback cooling allow a magnetic field gradient sensitivity of 1μTm−1/Hz" role="presentation" style="box-sizing: border-box; display: inline; font-size: 12.88px; line-height: normal; word-spacing: normal; overflow-wrap: normal; white-space: nowrap; float: none; direction: ltr; max-width: none; max-height: none; min-width: 0px; min-height: 0px; border: 0px; padding: 0px; margin: 0px; …


Career Development And Personal Success Profile Of Students - Followers And Students - Potential Future Leaders: The Case Of Rit Croatia, Jasminka Samardzija, Joseph Kevin Walker, Vanda Bazdan Jan 2017

Career Development And Personal Success Profile Of Students - Followers And Students - Potential Future Leaders: The Case Of Rit Croatia, Jasminka Samardzija, Joseph Kevin Walker, Vanda Bazdan

Articles

This study examines the differences among students in terms of self-reported leadership characteristics. It was conducted among all three programs and four generations of undergraduates at RIT Croatia. The goal of this study is to determine the differences among students who report being more and less leadership prone (Potential Future Leaders and Followers, respectively) with regard to demographic characteristics, reported self reliance socialization pattern, college level and program choice, career focus attainment and development, and reported attitudes regarding the importance of specific personality traits in leadership, the importance of specific career development factors and success indicators. Research showed that generation …


Maternal Nutrient Intakes From Food And Drinks Consumed In Early Pregnancy In Ireland, Laura Mullaney, Shona Cawley, Rachel Kennedy, Amy C. O'Higgins, Daniel Mccartney, Michael J. Turner Jan 2017

Maternal Nutrient Intakes From Food And Drinks Consumed In Early Pregnancy In Ireland, Laura Mullaney, Shona Cawley, Rachel Kennedy, Amy C. O'Higgins, Daniel Mccartney, Michael J. Turner

Articles

Background: The aim of this observational study was to measure food, macronutrient and micronutrient intakes of women presenting for antenatal care and assess compliance with current nutritional recommendations.


Vitamin D Receptor Variants And Uncontrolled Asthma, Conor Kerley, Katrina Hutchinson, John Faul, Peter Greally, David Coghlan, Basil Elnazir, Michael Louw, Yury Rochev Jan 2017

Vitamin D Receptor Variants And Uncontrolled Asthma, Conor Kerley, Katrina Hutchinson, John Faul, Peter Greally, David Coghlan, Basil Elnazir, Michael Louw, Yury Rochev

Articles

BACKGROUND: Asthma is a common childhood respiratory disease, affecting around 20% of Irish children. In other populations, vitamin D receptor (VDR) polymorphisms have been associated with asthma risk. We aimed to investigate the association between 2 VDR polymorphisms and uncontrolled paediatric asthma. METHODS: 44 asthmatic children and 57 healthy volunteers were studied. The VDR TaqI gene variant in exon 9 (T/C) (rs731236) and ApaI (rs7975232) in intron 8 (C/T) were determined, using TaqMan®Assays. The lung function, serum 25-hydroxyvitamin D (25OHD) levels and other biomarkers of allergy, immunity, airway and systemic inflammation were assessed. RESULTS: The distribution of T and C …


Outcomes Of Exclusive Enteral Nutrition In Paediatric Crohn's Disease, L. Lafferty, M. Tuohy, A. Carey, Sheila Sugrue, M. Hurley, Seamus Hussey Jan 2017

Outcomes Of Exclusive Enteral Nutrition In Paediatric Crohn's Disease, L. Lafferty, M. Tuohy, A. Carey, Sheila Sugrue, M. Hurley, Seamus Hussey

Articles

Background/objectives: Exclusive enteral nutrition (EEN) is a safe and effective treatment modality for inducing remission in paediatric Crohn's disease (CD). The primary aim of this study was to compare the outcomes of EEN to corticosteroid (CS) therapy in newly diagnosed, treatment-naïve patients with CD. A secondary aim was to describe the outcomes of EEN in a national cohort of paediatric CD patients over a 10-year period.

Subjects/methods: A retrospective chart review was conducted at the Irish national referral centre for paediatric CD. A case-matched analysis was conducted on two cohorts matched for age, gender, disease location, disease behaviour and disease …


Sinapinic And Protocatechuic Acids Found In Rapeseed: Isolation, Characterisation And Potential Benefits For Human Health As Functional Food Ingredients, Leah Quinn, Steven G. Gray, Steve Meaney, Steven Fiinn, Owen Kenny, Maria Hayes Jan 2017

Sinapinic And Protocatechuic Acids Found In Rapeseed: Isolation, Characterisation And Potential Benefits For Human Health As Functional Food Ingredients, Leah Quinn, Steven G. Gray, Steve Meaney, Steven Fiinn, Owen Kenny, Maria Hayes

Articles

Rapeseed is a globally valuable crop, and its production has steadily grown over the past 20 yr. Rapeseed is cultivated in China, India, Canada and Europe; however, in terms of rapeseed production, Europe is the largest producer (Carre, 2014). In the year 2013/2014, the European Union (EU) produced 9.93 million t of rapeseed oil, while China produced 6.58 million t (List, 2015). A by-product of the rapeseed oil industry, rapeseed meal contains bioactive constituents, such as the phenolics sinapinic acid (SA) and protocatechuic acid (PCA), which have potential uses as functional food ingredients and for use in cosmetic and pharmaceutical …


Cd10 − /Aldh − Cells Are The Sole Cisplatin-Resistant Component Of A Novel Ovarian Cancer Stem Cell Hierarchy, Brendan Ffrench, Claudia Gasch, Karsten Hokamp, Cathy Spillane, Gordon Blackshields, Thamir Mahmoud Mahgoub, Mark Bates, Louise Kehoe, Aoibhinn Mooney, Ronan Doyle, Brendan Doyle, Dearbhaile O ’ Donnell, Noreen Gleeson, Bryan T Hennessy, Britta Stordal, Ciaran O ’ Riain, Helen Lambkin Jan 2017

Cd10 − /Aldh − Cells Are The Sole Cisplatin-Resistant Component Of A Novel Ovarian Cancer Stem Cell Hierarchy, Brendan Ffrench, Claudia Gasch, Karsten Hokamp, Cathy Spillane, Gordon Blackshields, Thamir Mahmoud Mahgoub, Mark Bates, Louise Kehoe, Aoibhinn Mooney, Ronan Doyle, Brendan Doyle, Dearbhaile O ’ Donnell, Noreen Gleeson, Bryan T Hennessy, Britta Stordal, Ciaran O ’ Riain, Helen Lambkin

Articles

No abstract provided.


Advances In Control Of Food Mixing Operations, Patrick J. Cullen, Serafim Bakalis, Carl Sullivan Jan 2017

Advances In Control Of Food Mixing Operations, Patrick J. Cullen, Serafim Bakalis, Carl Sullivan

Articles

Mixing is a ubiquitous unit operation within the food industry and employed not only to combine multiple ingredients, but also to control reactions and modify the structure of foods. Failure of the mixing process may result in poor quality, organoleptic or functional attributes of foods along with product safety concerns. The industry is increasingly adopting automation and advanced control strategies such as Process Analytical Technology. Sensors can provide both insights into the complex mechanisms of mixing along with effective control. Here we discuss some recent advances in the control of food mixing operations.


Cancer Incidence In Ireland—The Possible Role Of Diet, Nutrition And Lifestyle, Daniel Mccartney, Declan Byrne, Marie Cantwell, Michael Turner Jan 2017

Cancer Incidence In Ireland—The Possible Role Of Diet, Nutrition And Lifestyle, Daniel Mccartney, Declan Byrne, Marie Cantwell, Michael Turner

Articles

Aim This observational ecological study aims to compare Ireland’s age-specific cancer incidence rates (ASRs) with equivalent European and global data and to highlight possible dietary, nutritional and lifestyle contributors to cancer in Ireland.

Subjects and methods Using the International Agency for Research on Cancer’s (IARC) GLOBOCAN database, Irish ASRs for all-site cancer and for "lifestyle-related" cancers such as those of the colo-rectum, oesophagus, breast, lung and prostate were compared with European and global incidence data. Irish dietary and nutrient intake data were reviewed and evaluated in the context of these cancer incidence data and in relation to the established dietary, …


Pcr-Ribotype Distribution Of Clostridium Difficile In Irish Pigs, Katharina Stein, Sarah Egan, Helen Lynch, Celine Harmanus, Lorraine Kyne, Celine Herra, Sinead Mcdermott, Ed Kuijper, Fidelma Fitzpatrick, Susan Fitzgerald, Lynda Fenelon, Denise Drudy Jan 2017

Pcr-Ribotype Distribution Of Clostridium Difficile In Irish Pigs, Katharina Stein, Sarah Egan, Helen Lynch, Celine Harmanus, Lorraine Kyne, Celine Herra, Sinead Mcdermott, Ed Kuijper, Fidelma Fitzpatrick, Susan Fitzgerald, Lynda Fenelon, Denise Drudy

Articles

Clostridium difficile is an important enteric pathogen in humans causing infections in the healthcare environment and the community. Carriage of C. difficile and C. difficile-related enterocolitis has been reported in piglets worldwide. The aim of this study was to investigate the rates of C. difficile isolation from pigs in Ireland. Faecal samples from piglet litters and sows were collected from six farms in 2015. The sows were non-diarrhoeal at the time of sampling. The diarrhoeal status of the piglets was unknown. C. difficile was isolated from 34/44 (77%) of piglet litter samples and from 33/156 (21%) of sow samples. The …


Vitamin D Improves Selected Metabolic Parameters But Not Neuropsychological Or Quality Of Life Indices In Osa: A Pilot Study, Conor Kerley, Katrina Hutchinson, Jessica Branham, Aisling Mcgowan, John Faul, Liam Cormican Jan 2017

Vitamin D Improves Selected Metabolic Parameters But Not Neuropsychological Or Quality Of Life Indices In Osa: A Pilot Study, Conor Kerley, Katrina Hutchinson, Jessica Branham, Aisling Mcgowan, John Faul, Liam Cormican

Articles

Study Objectives: Our group and others have reported a high rate of vitamin D deficiency in obstructive sleep apnea (OSA), where vitamin D levels (25(OH) D) correlate negatively with OSA severity and some of its associated metabolic alterations. Data regarding vitamin D supplementation in OSA are lacking. We wanted to evaluate the effect of vitamin D3 supplementation on OSA symptoms and metabolic parameters. Methods: We conducted a pilot, double-blind, randomized, placebo-controlled trial of daily supplementation with 4,000 IU vitamin D3 (D3) or placebo (PL). We studied 19 Caucasian adults (14 male, mean age 55 y, mean body mass index [BMI] …


Broad-Scale Redistribution Of Mrna Abundance And Transcriptional Machinery In Response To Growth Rate In Salmonella Enterica Serovar Typhimurium, Andrew D. S. Cameron, Shane Dillon, Carsten Kröger, Laurens Beran, Charles Dorman Jan 2017

Broad-Scale Redistribution Of Mrna Abundance And Transcriptional Machinery In Response To Growth Rate In Salmonella Enterica Serovar Typhimurium, Andrew D. S. Cameron, Shane Dillon, Carsten Kröger, Laurens Beran, Charles Dorman

Articles

We have investigated the connection between the four-dimensional architecture of the bacterial nucleoid and the organism's global gene expression programme. By localizing the transcription machinery and the transcriptional outputs across the genome of the model bacterium Salmonella enterica serovar Typhimurium at different stages of the growth cycle, a surprising disconnection between gene dosage and transcriptional output was revealed. During exponential growth, gene output occurred chiefly in the Ori (origin), Ter (terminus) and NSL (non-structured left) domains, whereas the Left macrodomain remained transcriptionally quiescent at all stages of growth. The apparently high transcriptional output in Ter was correlated with an enhanced …