Digital Commons Network^™

Synergies In Scholarship At The Research Teaching Nexus At Tu Dublin: Building Research Synergies Into Teaching Activity Workshop, Deirdre Mcquillan

Articles

Objective of workshop is to provide and recognise possibilities for research synergies for individuals attending and to help participants develop more research supportive personal teaching philosophies. The workshop is evidence based and drawn from a survey of academics at TU Dublin in early 2021 on research synergies at the research teaching nexus.

Overview Of Hybrid Financial Instruments And Investment Leverage Enablers For Cultural Heritage Adaptive Reuse, Tracy Pickerill

Articles

Cultural heritage adaptive reuse investment strategies involve long-term, sometimes perpetual, investment horizons, which necessitate the integration of sustainable funding mechanisms. In order to achieve participatory circular human prosperity, the sustainable finance movement must re-evaluate investment leverage approaches including value creation models, the design of hybrid financial instruments, analytical decision-making frameworks,collaborative social enterprise structures, impact performance metrics and evolving mindsets.

In the context of this overview of financial and non-financial instruments, cultural heritage adaptive reuse activities include:

• Adaptive reuse of cultural built heritage structures

• Energy retrofit of cultural built heritage structures

• Protection and management of natural eco-systems;

• …

A Geometric Approach To Conditioning And The Search For Minimum Variance Unbiased Estimators, David L. Farnsworth, James E. Marengo

Articles

Our purpose is twofold: to present a prototypical example of the conditioning technique to obtain the best estimator of a parameter and to show that this technique resides in the structure of an inner product space. The technique uses conditioning of an unbiased estimator on a sufficient statistic. This procedure is founded upon the conditional variance formula, which leads to an inner product space and a geometric interpretation. The example clearly illustrates the dependence on the sampling methodology. These advantages show the power and centrality of this process.

(Re)Framing Race In Civil Rights Lawyering, Anthony V. Alfieri, Angela Onwuachi-Willig

Articles

This Review examines the significance of Henry Louis Gates, Jr.'s new book, Stony the Road: Reconstruction, White Supremacy, and the Rise of Jim Crow, for the study of racism in our nation's legal system and for the regulation of race in the legal profession, especially in the everyday labor of civil-rights and poverty lawyers, prosecutors, and public defenders. Surprisingly, few have explored the relevance of the racial narratives distilled by Gates in Stony the Roa - the images, stereotypes, and tropes that Whites constructed of Blacks to deepen and ensure the life and legacy of white supremacy-to the practice …

Pivot Points In Bivariate Linear Regression, David L. Farnsworth, Carl V. Lutzer

Articles

There are little-noticed points in the plane, which are artifacts of linear regression. The points, which are called pivot points, are the intersections of sets of regression lines. We derive the coordinates of the pivot point and explain its sources. We show how a pivot point arises in a certain notable data set, which has been analyzed often for points of high leverage. We obtain the application of pivot points that shortens calculations when updating a set of bivariate observations by adding a new point.

Challenging Domestic Injustice Through International Human Rights Advocacy: Addressing Homelessness In The United States, Eric Tarst, Tamar Ezer, Melanie Ng, David Stuzin, Conor Arevalo

Articles

This Article explores how international human rights norms and procedures can serve as a powerful tool in addressing injustice in the United States context, using work addressing the criminalization of homelessness as a case study. Moreover, it explores how civil and political rights and negative obligations by the government can serve as an entry point for asserting a more robust understanding of rights that includes social and economic rights and affirmative obligations by government. The Article documents and analyzes original work led by the National Homelessness Law Center and other pioneering advocates, reflecting on lessons learned and next steps to …

Proven Concepts In New Contexts: Applying Public Health, Mental Health, And Human Rights Strategies To Atrocity Prevention, Jocelyn Getgen Kestenbaum, Arlan F. Fuller, Caitlin O. Mahoney, Amy E. Meade

Articles

No abstract provided.

Democracy’S Destiny, Gilda Daniels

Articles

From its beginning, America has had a paradoxical democracy, where “all men are created equal” while simultaneously denying the right to vote to anyone who was not White, male, or owned property. The pandemic exposed the fault lines of our democratic form of government. Those imposing barriers to the ballot are facing off against the advocates of access. It is not a new battle. In America, we seek ways to limit who can participate instead of expanding opportunities. We have dedicated our resources to dancing around the edges of democracy, for example, advocating for vote by mail or automatic voter …

The Problem With Assumptions: Revisiting “The Dark Figure Of Sexual Recidivism”, Tamara Rice Lave, Jj Prescott, Grady Bridges

Articles

What is the actual rate of sexual recidivism given the well‐ known fact that many crimes go unreported? This is a difficult and important problem, and in “The dark figure of sexual recidivism,” Nicholas Scurich and Richard S. John (2019) attempt to make progress on it by “estimat[ing] actual recidivism rates . . . given observed rates of reoffending” (p. 171). In this article, we show that the math in their probabilistic model is flawed, but more importantly, we demonstrate that their conclusions follow ineluctably from their empirical assumptions and the unrepresentative empirical research they cite to benchmark their calculations. …

Deal Protection Devices, Albert H. Choi

Articles

In mergers and acquisitions transactions, a buyer and a seller will often agree to contractual mechanisms (deal protection devices) to deter third parties from jumping the deal and to compensate a disappointed buyer. With the help of auction theory, this Article analyzes various deal protection devices, while focusing on the two most commonly used mechanisms: match rights and target termination fees. A match right gives the buyer a right to “match” a third party’s offer so as to prevent the third party from snatching the target away, while a termination fee compensates the buyer when a third party acquires the …

Contract Design When Relationship-Specific Investment Produces Asymmetric Information, Albert H. Choi, George Triantis

Articles

Under conventional contract theory, contracts may be efficient by protecting relationship specific investment from holdup in subsequent (re)negotiation over terms of trade. This paper demonstrates a different problem when specific investment also provides significant private information to the investing party. This is fairly common: for example, a manufacturer invests to learn about its buyer's idiosyncratic needs or a collaborator invests to learn about a joint venture. We show how such private information can lead to subsequent bargaining failure and suboptimal ex ante relationship-specific investment. We also show that this inefficiency is worse if the parties enter into a binding and …

Trade Administration, Kathleen Claussen

Articles

At the core of public debates about trade policy making in the United States and the so-called "trade war" is a controversy over who should be responsible for making U.S. trade law: Congress or the President. What these important conversations miss is that underlying much of our trade policy in recent decades is a widespread executive-branch lawmaking apparatus with monitoring, rulemaking, adjudicative, and enforcement features that operates in considerable shadow. Executive branch agencies are now the primary actors in trade lawmaking. This Article excavates that critical underbelly: what I call our "trade administrative state." It maps the trade administrative state's …

E-Cigarettes And Smoking In Irish Teens: A Logistic Regression Analysis Of Current (Past 30-Day) Use Of E-Cigarettes, Joan Hanafin, Salome Sunday, Luke Clancy

Articles

Aim

Electronic cigarette (e-cigarette) use among Irish teenagers has risen significantly. In 2019, prevalence of current use (last 30 days) among 15–17-year-olds was 17.3%. We examine social determinants of adolescent e-cigarette current use.

Subject and methods

A stratified random sample of 50 schools in Ireland was surveyed in 2019, part of the European School Survey Project on Alcohol and other Drugs (ESPAD), with 3495 students aged 15, 16, and 17. Bivariate and multivariable logistic regression [providing adjusted odds ratios (AORs)] analyses were performed using Stata version 16.

Results

Current e-cigarette users were more likely to be male (AOR = 0.55, …

Cy Prés Settlements In Privacy Class Actions / Acuerdos Cy Prés En Acciones De Clase Sobre Privacidad, Thomas E. Kadri, Ignacio N. Cofone

Articles

This essay considers the potential for using cy prés settlements in privacy class actions. These settlements are a procedural mechanism to overcome distribution challenges in class actions. When it is too burdensome to prove individual claims or too costly to distribute damages to class members, courts on occasions award damages to a charity or non-profit organization involved in work serving the class members' interests. These controversial settlements have been gaining attention in various legal systems. The U.S. Supreme Court recently considered their propriety in Frank v. Gaos, while courts in Canada and several Latin American countries have been experimenting with …

The Separation Of Voting And Control: The Role Of Contract In Corporate Governance, Gabriel V. Rauterberg

Articles

The default rules of corporate law make shareholders’ control rights a function of their voting power. Whether a director is elected or a merger is approved depends on how shareholders vote. Yet, in private corporations shareholders routinely alter their rights by contract. This phenomenon of shareholder agreements—contracts among the owners of a firm— has received far less attention than it deserves, mainly because detailed data about the actual contents of shareholder agreements has been lacking. Private companies disclose little, and shareholder agreements are thought to play a trivial or nonexistent role in public companies. I show that this is false—fifteen …

Novel Facet Of An Old Dietary Molecule? Direct Influence Of Caffeine On Glucose And Biogenic Amine Handling By Human Adipocytes, Wiem Haj Ahmed, Nathalie Boulet, Anaïs Briot, Barry J. Ryan, Gemma K. Kinsella, Jeffrey O’Sullivan, Francisco Les, Josep Mercader-Barceló, Gary T. Henehan, Christian Carpéné

Articles

Caffeine is a plant alkaloid present in food and beverages consumed worldwide. It has high lipid solubility with recognized actions in the central nervous system and in peripheral tissues, notably the adipose depots. However, the literature is scant regarding caffeine’s influence on adipocyte functions other than lipolysis, such as glucose incorporation into lipids (lipogenesis) and amine oxidation. The objective of this study was to explore the direct effects of caffeine and of isobutylmethylxanthine (IBMX) on these adipocyte functions. Glucose transport into fat cells freshly isolated from mice, rats, or humans was monitored by determining [3H]-2-deoxyglucose (2-DG) uptake, while the incorporation …

Β-Glucosidase From Streptomyces Griseus: Ester Hydrolysis And Alkyl Glucoside Synthesis In The Presence Of Deep Eutectic Solvents, Albert Uhoraningoga, Gemma K. Kinsella, Gary T. Henehan, Barry J. Ryan

Articles

Deep Eutectic Solvents (DES) are ionic liquid analogs that have attracted considerable attention as green solvents for biocatalytic transformations. The use of DES as part of a ‘solvent engineering’ approach to enhance enzyme stability holds great promise since they are biodegradeable, relatively inexpensive and environmentally safe media for enzyme reactions. However, the behaviour of specific enzymes in such solvents is complex; some enzymes are inhibited in DES, while others appear to be activated.

Glucosidases are among the most widely used enzymes for commercial chemoenzymatic synthesis. In particular, their application in the synthesis of biodegradable alkyl glucosides by reverse hydrolysis is …

Metatheme Analysis: A Qualitative Method For Cross-Cultural Research, Amber Wutich, Melissa Beresford, Cindi Sturtzsreetharan, Alexandra Brewis, Sarah Trainer, Jessica Hardin

Articles

In recent years, there has been a florescence of cross-cultural research using ethnographic and qualitative data. This cutting-edge work confronts a range of significant methodological challenges, but has not yet addressed how thematic analysis can be modified for use in cross-cultural ethnography. Thematic analysis is widely used in qualitative and mixed-methods research, yet is not currently well-adapted to cross-cultural ethnographic designs. We build on existing thematic analysis techniques to discuss a method to inductively identify metathemes (defined here as themes that occur across cultures). Identifying metathemes in crosscultural research is important because metathemes enable researchers to use systematic comparisons to …

Temperature-Sensitive Holograms With Switchable Memory, Muhammad Irfan Dr, Suzanne Martin Dr, Izabela Naydenova Prof

Articles

Abstract

Herein, the dynamics and reversibility of temperature-induced changes in volume phase holographic gratings (VPHGs) recorded in the low-toxicity self-processing photopolymer poly(N-isopropyl acrylamide) (poly-NIPA) are reported on. Transmission and reflection gratings are exposed to temperatures ranging 8–60 °C to study the effect of temperature on their properties. First, the role of the photopolymer chemical composition is investigated by comparing layers containing NIPA with those containing acrylamide (AA) and measuring the normalized diffraction efficiency (DE) at 60 °C; higher thermal sensitivity is observed for poly-NIPA gratings (24% drop) versus low sensitivity for AA gratings (2% increase). The impact of …

A Tighter Constraint On Earth-System Sensitivity From Long-Term Temperature And Carbon-Cycle Observations, Tony E. Wong, Ying Cui, Dana L. Royer, Klaus Keller

Articles

The long-term temperature response to a given change in CO2 forcing, or Earth-system sensitivity (ESS), is a key parameter quantifying our understanding about the relationship between changes in Earth’s radiative forcing and the resulting long-term Earth-system response. Current ESS estimates are subject to sizable uncertainties. Long-term carbon cycle models can provide a useful avenue to constrain ESS, but previous efforts either use rather informal statistical approaches or focus on discrete paleoevents. Here, we improve on previous ESS estimates by using a Bayesian approach to fuse deep-time CO2 and temperature data over the last 420 Myrs with a long-term carbon cycle …

An Lpc Pole Processing Method For Enhancing The Identification Of Dominant Spectral Features, Jin Xu, Mark Davis, Ruairí De Fréin

Articles

This paper proposes a new time-resolved spectral analysis method based on a modification to the linear predictive coding (LPC) method for enhancing the identification of the dominant frequencies of a signal. The method described here is based on a z-plane analysis of the LPC poles. These poles are used to produce a series of reduced order filter transfer functions which can accurately identify and estimate the frequency of the dominant spectral features. The standard LPC method has been shown to suffer from a sensitivity to noise and its performance is dependent on the filter order. The proposed method can …

Internet Of Medical Things (Iomt): Overview, Emerging Technologies, And Case Studies, Sahshanu Razdan, Sachin Sharma

Articles

No abstract provided.

Why Parents Chose To Send Their Children To Irish-Medium Immersion Preschools: Learning From Parental Choice Strategies In Celtic Countries, Maire Mhic Mhathuna, Fiona Nic Fhionnlaoich

Articles

This study investigated the reasons Irish parents chose to send their children to Irish-medium preschools settings over other forms of early childhood education. The international literature on parental decision making regarding childcare and relevant studies on immersion education in Celtic countries were reviewed. A parental questionnaire, informed by this literature, was distributed through selected immersion settings in Ireland. Social and cognitive development were the main reasons parents cited in regard to early childhood education and an interest in the Irish language and bilingualism along with the good reputation of the immersion preschool were the reasons they chose immersion preschooling. Comparisons …

Episodic Occurrence Of Favourable Weather Constrains Recovery Of A Cold Desert Shrubland After Fire, Alexandra K. Urza, Peter J. Weisberg, David Board, Jeanne C. Chambers, Stanley G. Kitchen, Bruce A. Roundy

Articles

1. Key to the long-term resilience of dryland ecosystems is the recovery of foundation plant species following disturbance. In ecosystems with high interannual weather variability, understanding the influence of short-term environmental conditions on establishment of foundation species is essential for identifying vulnerable landscapes and developing restoration strategies. We asked how annual environmental conditions affect post-fire establishment of Artemisia tridentata, a shrub species that dominates landscapes across much of the western United States, and evaluated the influence of episodic establishment on population recovery.
2. We collected A. tridentata stem samples from 33 plots in 12 prescribed fire sites that burned 8–11 years …

Unveiling Women’S Needs And Expectations As Users Of Bike Sharing Services: The H2020 Diamond Project, Andrea Gorrini, Rawad Choubassi, Federico Messa, Wafaa Saleh, Augustus Ababio-Donkor, Maria Chiara Leva, Lorraine D'Arcy, Francesco Fabbri, David Laniado, Pablo Aragon

Articles

Within the objectives of the H2020 DIAMOND project, the paper investigates women’s needs and expectations as users of the bike-sharing service managed by Syndicat Mixte Autolib et Velib Métropole in the territory of Paris Region-Petite Couronne (France). The paper presents a thematic literature review focused on gender inclusion in bike-sharing schemes. The proposed methodological approach is based on (i) Geographic Information Systems for the analysis of geolocated open datasets related to land, sociodemographic and mobility characteristics of the areas surrounding each docking stations. This was aimed at identifying a short list of suitable bike-sharing docking stations, which were further characterized …

U-251mg Spheroid Generation Using A Scaffold Based Method Protocol, Lara Carroll, Brijesh K. Tiwari, James F. Curtin, Janith Wanigasekara

Articles

3D cell culture is a technique that is used to grow cells in vitro that will mimic an in vivo environment. 3D cell models are a helpful learning tool for researchers to better understand disease mechanisms and to explore different therapeutic properties of drugs. 3D cell cultures can be developed using patient derived cancer cells. Once they have been grown, these 3D cells can be used to screen for small molecule drugs or for genetic modification in for analysis of disease pathways or to predict drug treatments toxicity or efficacy. 3D cell cultures are a big step towards the more …

U-251mg Spheroid Generation Using Hanging Drop Method Protocol, Lara Carroll, Brijesh K. Tiwari, James F. Curtin, Janith Wanigasekara

Articles

The use of 3D cell culture has been a major step in developing cellular models that can mimic physiological tissues. Traditional 2D cell cultures are often unable to accurately represent the cellular functions and responses that are present in tissues, as a result, research findings based on 2D cultures tend to be skewed with limited predictive capability. 3D cell cultures can be grown from cells obtained from cancer organoids in patients. These models are useful for understanding disease mechanisms and exploring drug therapeutics in areas such as toxicity and efficacy. In order to gather more physiologically relevant data, a variety …

U-251mg Spheroid Generation Using Low Attachment Plate Method Protocol, Lara J. Carroll, Brijesh K. Tiwari, James F. Curtin, Janith Wanigasekara

Articles

3D cell culture is a process used to grow cells in vitro to mimic an in vivo environment. 3D cell models are very useful for understanding disease mechanisms and exploring drug therapeutics. 3D cultures can be grown from cells taken from cancer organoids in patients. Once grown, they can be used to screen for small molecule drugs or they can be genetically modified in order to analyse disease pathways or predict the toxicity or efficacy of a drug treatment. These cultures decrease the need to use animals in research and provides more reliable results as it uses human physiology. This …

Raman Spectroscopic Characterisation Of Non Stimulated And Stimulated Human Whole Saliva, Genecy Calado, Isha Behl, Hugh Byrne, Fiona Lyng

Articles

Human saliva is a unique biofluid which can reflect the physiopathological state of an individual. The wide spectrum of molecules present in saliva, compounded by the close association of salivary composition to serum metabolites, can provide valuable information for clinical diagnostic applications through highly sensitive vibrational spectroscopic techniques such as Raman spectroscopy. However, the nature of saliva, in terms of collection and patient-related characteristics, can be considered factors which may strongly affect the Raman spectral profile of salivary samples and disrupt the search for specific salivary biomarkers in the detection of diseases. The main objective of this study was to …

Mining And Managing Big Data Refactoring For Design Improvement: Are We There Yet?, Eman Abdullah Alomar, Mohamed Wiem Mkaouer, Ali Ouni

Articles

Refactoring is a set of code changes applied to improve the internal structure of a program, without altering its external behavior. With the rise of continuous integration and the awareness of the necessity of managing technical debt, refactoring has become even more popular in recent software builds. Recent studies indicate that developers often perform refactorings. If we consider all refactorings performed across all projects, this consists of the refactoring knowledge that represents a rich source of information that can be useful for both developers and practitioners to better understand how refactoring is being applied in practice. However, mining, processing, and …