Digital Commons Network^™

Size Dependent Translocation And Fetal Accumulation Of Gold Nanoparticles From Maternal Blood In The Rat., Manuela Semmler-Behnke, Jens Lipka, Alexander Wenk, Martin Schäffler, Furong Tian, Günter Schmid, Günter Oberdörster, Wolfgang G. Kreyling

Articles

Background

There is evidence that nanoparticles (NP) cross epithelial and endothelial body barriers. We hypothesized that gold (Au) NP, once in the blood circulation of pregnant rats, will cross the placental barrier during pregnancy size-dependently and accumulate in the fetal organism by 1. transcellular transport across the hemochorial placenta, 2. transcellular transport across amniotic membranes 3. transport through ~20 nm wide transtrophoblastic channels in a size dependent manner. The three AuNP sizes used to test this hypothesis are either well below, or of similar size or well above the diameters of the transtrophoblastic channels.

Methods

We intravenously injected monodisperse, negatively …

Response Of Conifer-Encroached Shrublands In The Great Basin To Prescribed Fire And Mechanical Treatments, Richard F. Miller, Jaime Ratchford, Bruce A. Roundy, Robin J. Tausch, April Hulet, Jeanne C. Chambers

Articles

In response to the recent expansion of piñon and juniper woodlands into sagebrush-steppe communities in the northern Great Basin region, numerous conifer-removal projects have been implemented, primarily to release understory vegetation at sites having a wide range of environmental conditions. Responses to these treatments have varied from successful restoration of native plant communities to complete conversion to nonnative invasive species. To evaluate the general response of understory vegetation to tree canopy removal in conifer-encroached shrublands, we set up a region-wide study that measured treatment-induced changes in understory cover and density. Eleven study sites located across four states in the Great …

Rrd1p, An Rna Polymerase Ii-Specific Prolyl Isomerase And Activator Of Phosphoprotein Phosphatase, Promotes Transcription Independently Of Rapamycin Response., Rwik Sen, Shivani Malik, Sarah Frankland-Searby, Bhawana Uprety, Shweta Lahudkar, Sukesh R Bhaumik

Articles

Rrd1p (resistance to rapamycin deletion 1) has been previously implicated in controlling transcription of rapamycin-regulated genes in response to rapamycin treatment. Intriguingly, we show here that Rrd1p associates with the coding sequence of a galactose-inducible and rapamycin non-responsive GAL1 gene, and promotes the association of RNA polymerase II with GAL1 in the absence of rapamycin treatment following transcriptional induction. Consistently, nucleosomal disassembly at GAL1 is impaired in the absence of Rrd1p, and GAL1 transcription is reduced in the Δrrd1 strain. Likewise, Rrd1p associates with the coding sequences of other rapamycin non-responsive and inducible GAL genes to promote their transcription in …

Culinary Internship And The European Mobility Action Plan: Part One, Frank Cullen

Articles

International mobility for work placement has experienced exponential growth over the past five years with the assistance of European Leonardo da Vinci and Erasmus funding for European internships. The main purpose behind the European Commission funding ventures for internship (experiential learning) is to enhance the students’ cultural awareness, cultivate their language skills and develop their professionalism in their field of study. It is generally accepted that experiential learning in the workplace provides many learning opportunities for students (Billett, 2001:121, Fuller and Unwin, 2003, Guile and Griffiths, 2001, Cullen, 2010a, Cullen, 2010b, Kristensen, 2004). In spite of acceptance that experiential learning …

A Soft Condensed Matter Approach Towards Mathematical Modelling Of Mass Transport And Swelling In Food Grains, Michael Chapwanya, N. Misra

Articles

Soft condensed matter (SCM) physics has recently gained importance for a large class of engineering materials. The treatment of food materials from a soft matter perspective, however, is only at the surface and is gaining importance for understanding the complex phenomena and structure of foods. In this work, we present a theoretical treatment of navy beans from a SCM perspective to describe the hydration kinetics. We solve the transport equations within a porous matrix and employ the Flory–Huggin’s equation for polymer–solvent mixture to balance the osmotic pressure. The swelling of the legume seed is modelled as a moving boundary with …

An Off-Label Use Of Parental Rights? The Unanticipated Doctrinal Antidote For Professor Mnookin's Diagnosis, Emily Buss

Articles

No abstract provided.

Bacteria On Shared Mobile Phones Can Lead To Infections, Roberta Basol, Jean Beckel, Judy Gilsdorf-Gracie, Amy Hilleren-Listerud, Terri Mccaffrey, Sherri Reischl, Pamela Rickbeil, Mary Schimnich, Kirsten Skillings, Mary A. Struffert

Articles

It's now a common practice for hospital-owned mobile phones to be shared among healthcare employees from shift to shift. Despite the benefit of increased, timely communication between caregivers, sharing mobile devices can lead to the spread of healthcare-associated infections (HAIs) if they aren't properly disinfected. The Guidelines for Disinfection and Sterilization in Healthcare Facilities describe "non-critical environmental surfaces" as items that are frequently touched by the hand and may pose a risk of secondary infection transmission.

The Intersection Of Family Law And Education Law, Debra Chopp

Articles

It is well-established that parents have a fundamental liberty interest in directing the education of their children. As family law practitioners know, however, parents do not always agree with each other on matters pertaining to their child's education. Where education issues arise in family law cases, it is important for members of the family law bar to have familiarity with education laws so that they may properly advise their clients. This article will identify and briefly discuss common intersections of family law and education law.

Footwear And Wrist Communication Links Using 2.4 Ghz And Uwb Antennas, Domenico Gaetano, Patrick Mcevoy, Max Ammann, Colm Brannigan, Louise Keating, Frances Horgan

Articles

It is reported that wearable electronic devices are to be used extensively in the next generation of sensors for sports and health monitoring. The information obtained from sensors on the human body depends on the biological parameters, the measurement rate and the number of sensors. The choice of the wireless protocol depends on the required data rates and on system configurations. The communication link quality is achieved with narrowband technologies such as Bluetooth or Zigbee, provided that the number of sensors is small and data rates are low. However, real-time measurements using wideband channels may also be necessary. This paper …

Studies On The Synthesis Of Orthogonally Protected Azalanthionines, And Of Routes Towards B-Methyl Azalanthionines, By Ring-Opening Of N-Activated Aziridine-2-Crboxylates, Keith O'Brien, Keith Ó Proinsias, Fintan Kelleher

Articles

Orthogonally protected azalanthionines were successfully synthesised by the ring-opening of N-activated aziridine-2-carboxylates with protected diaminopropanoic acids (DAPs). The required DAPs were also prepared by ring-opening of N-activated aziridine-2-carboxylates with para-methoxybenzylamine, but it was found that the choice of aziridine protecting groups dictated both the success of the reaction as well as the regioselectivity of the isolated products. Attempts to extend the methodology to the preparation of the more sterically demanding b-methyl azalanthionines have, so far, been unsuccessful.

Legal Protections For The 'Personal Best' Of Each Employee: Title Vii's Prohibition On Sex Discrimination, The Legacy Of Price Waterhouse V. Hopkins, And The Prospect Of Enda, Mary Anne Case

Articles

No abstract provided.

Legal Protections For The 'Personal Best' Of Each Employee: Title Vii’S Prohibition On Sex Discrimination, The Legacy Of Price Waterhouse V. Hopkins, And The Prospect Of Enda, Mary Anne Case

Articles

No abstract provided.

Fraud And Abuse In Mesothelioma Litigation, Lester Brickman

Articles

No abstract provided.

Mechanical Mastication Of Utah Juniper Encroaching Sagebrush Steppe Increases Inorganic Soil N, Kert R. Young, Bruce A. Roundy, Dennis L. Eggett

Articles

Juniper (Juniperus spp.) has encroached on millions of hectares of sagebrush (Artemisia spp.) steppe. Juniper mechanical mastication increases cover of understory species but could increase resource availability and subsequently invasive plant species. We quantified the effects of juniper mastication on soil resource availability by comparing total C, total N, C : N ratio, Olsen extractable P, sulfate S, and pH using soil samples and inorganic N (NO₃^-+NH₄⁺) using ion exchange membranes. We compared resource availability in paired masticated and untreated areas in three juniper-dominated sagebrush and bunchgrass ecosystems in the Utah portion …

Microfiber Coupler Based Label-Free Immunosensor, Lin Bo, Christy Charlton O'Mahony, Yuliya Semenova, Niamh Gilmartin, Pengfei Wang, Gerald Farrell

Articles

Optical microfibers and related structures which incorporate large evanescent field and minimal size offer new opportunities for biosensing applications. In this paper we report the development of an immunosensor based on a tapered microfiber coupler embedded in a low refractive index polymer. Biomolecules adsorbed on the microfiber coupler surface modify the surrounding refractive index. By immobilizing antigens on the surface of the sensing area, the microfiber coupler was able to operate as a label-free immunosensor to detect specific antibodies. We experimentally demonstrated for the first time the sensing ability of this sensor using a fibrinogen antigen-antibody pair. By monitoring the …

Field Penetration In Mri-Based Breast Models: A Numerical Investigation, Giuseppe Ruvio, Raffaele Solimene, Antonio Cuccaro, Max Ammann

Articles

The use of reliable computational tools is fundamental to investigate different aspects of microwave breast cancer imaging. From the development of high-definition and realistic numerical breast models, different coupling mechanisms and the reaction of different tissues to microwave signals can be characterized. In this paper, field penetration inside four numerical breast phantoms with varying adipose content is evaluated in the frequency range 0.5 - 10 GHz across sagittal cuts.

Improved Protocols For Vibrational Spectroscopic Analysis Of Body Fluids, Franck Bonnier, François Petitjean, Matthew Baker, Hugh Byrne

Articles

The applications of vibrational spectroscopy to the examination of human blood serum are explored. Although FTIR spectra can be recorded in aqueous solutions at (gelatin) concentrations as low as 100mg/L, the high-wavenumber region remains obscured by water absorption. Using Raman spectroscopy, high quality spectra of gelatine solutions as low as 10mg/L can be achieved, also covering the high-wavenumber regions. In human serum, spectral profiles are weak and partially obscured by water features. Dried deposits are shown to be physically and chemically inhomogeneous resulting in reduced measurement reproducibility. Concentration of the serum using commercially available centrifugal filter devices results in an …

Dna → Rna: What Do Students Think The Arrow Means?, Leslie Kate Wright, J. Nick Fisk, Dina L. Newman

Articles

The central dogma of molecular biology, a model that has remained intact for decades, describes the transfer of genetic information from DNA to protein though an RNA intermediate. While recent work has illustrated many exceptions to the central dogma, it is still a common model used to describe and study the relationship between genes and protein products. We investigated understanding of central dogma concepts and found that students are not primed to think about information when presented with the canonical figure of the central dogma. We also uncovered conceptual errors in student interpretation of the meaning of the transcription arrow …

In-Package Atmospheric Pressure Cold Plasma Treatment Of Cherry Tomatoes, N. Misra, Kevin Keener, Paula Bourke, J Mosnier, Patrick J. Cullen

Articles

Cold plasma is increasingly under research for decontamination of foods, especially fresh fruits and vegetables. The effect of cold plasma on food quality, however, remains under researched. This study investigates the effects of cold plasma generated within a sealed package from a dielectric barrier discharge on the physical quality parameters and respiration rates of cherry tomatoes. Respiration rates and weight loss were monitored continuously, while other parameters are reported at the end of storage period. Differences among weight loss, pH and firmness for control and treated cherry tomatoes were insignificant towards the end of storage life. Changes in respiration rates …

We The Peoples: The Global Origins Of Constitutional Preambles, Tom Ginsburg, Daniel Rockmore, Nick Foti

Articles

No abstract provided.

Incentives For Reporting Disease Outbreaks, Ramanan Laxminarayan, Julian Reif, Anup Malani

Articles

Background: Countries face conflicting incentives to report infectious disease outbreaks. Reports of outbreaks can prompt other countries to impose trade and travel restrictions, which has the potential to discourage reporting. However, reports can also b

In-Package Atmospheric Pressure Cold Plasma Treatment Of Strawberries, N. Misra, Paula Bourke, Patrick J. Cullen, Sonal Patil

Articles

The ability to generate low temperature plasma at atmospheric pressure offers new opportunities to decontaminate biological materials, including fresh foods. In this study, strawberries were treated with atmospheric cold plasma (ACP), generated with a 60 kV dielectric barrier discharge (DBD) pulsed at 50 Hz, across a 40 mm electrode gap, generated inside a sealed package containing ambient air (42% relative humidity). The current-voltage characteristics revealed that the plasma operated in the filamentary regime. The background microflora (aerobic mesophillic bacteria, yeast and mould) of strawberries treated for 5 min was reduced by 2 log 10 within 24 h of post-ACP treatment. …

In-Package Nonthermal Plasma Degradation Of Pesticides On Fresh Produce, N. Misra, Shashi Pankaj, Tony Walsh, Finbarr O'Regan, Paula Bourke, Patrick J. Cullen

Articles

In-package nonthermal plasma (NTP) technology is a novel technology for the decontamination of foods and biological materials. This study presents the first report on the potential of the technology for the degradation of pesticide residues. A cocktail of pesticides, namely Azoxystrobin, Cyprodinil, Fludioxonil and Pyriproxyfen was tested on strawberries. The concentrations of these pesticides were monitored in priori and post- plasma treatment using GC-MS/MS. An applied voltage and time dependent degradation of the pesticides was observed for treatment voltages of 60, 70 and 80 kV and treatment durations ranging from 1 to 5 min, followed by 24 h in-pack storage. …

Hydrologic And Erosion Responses To Wildfire Along The Rangeland-Xeric Forest Continuum In The Western Us: A Review And Model Of Hydrologic Vulnerability, Christopher Jason Williams, Frederick B. Pierson, Peter R. Robichaud, Jan Boll

Articles

The recent increase in wildfire activity across the rangeland–xeric forest continuum in the western United States has landscape-scale consequences in terms of runoff and erosion. Concomitant cheatgrass (Bromus tectorum L.) invasions, plant community transitions and a warming climate in recent decades along grassland–shrubland–woodland–xeric forest transitions have promoted frequent and large wildfires, and continuance of the trend appears likely if warming climate conditions prevail. These changes potentially increase overall hydrologic vulnerability by spatially and temporally increasing soil exposure to runoff and erosion processes. Plot and hillslope-scale studies demonstrate burning may increase event runoff or erosion by factors of 2–40 over …

Identification Of Quantitative Trait Loci (Qtl) Underlying Protein, Oil, And Five Major Fatty Acids’ Contents In Soybean, M Akond, Shiming Liu, Melanie Boney, Stella K. Kantartzi, David A. Lightfoot, Nacer Bellaloui, Khalid Meksem, My Abdelmajid Kassem

Articles

Improved seed composition in soybean [Glycine max (L.) Merr.] for protein and oil quality is one of the major goals of soybean breeders. A group of genes that act as quantitative traits with their effects can alter protein, oil, palmitic, stearic, oleic, linoleic, and linolenic acids percentage in soybean seeds. The objective of this study was to identify Quantitative Trait Loci (QTL) controlling protein, oil, and fatty acids content in a set of F5:8 RILs de-rived from a cross between lines, ‘MD 96-5722’ and ‘Spencer’ using 5376 Single Nucleotide Polymorphism (SNP) markers from the Illumina Infinium SoySNP6K BeadChip array. QTL …

Identification Of Quantitative Trait Loci (Qtl) Underlying Protein, Oil, And Five Major Fatty Acids’ Contents In Soybean, Masum Akond, Shiming Liu, Melanie Boney, Stella K. Kantartzi, Khalid Meksem, Nacer Bellaloui, David A. Lightfoot, My Abdelmajid Kassem

Articles

Improved seed composition in soybean [Glycine max (L.) Merr.] for protein and oil quality is one of the major goals of soybean breeders. A group of genes that act as quantitative traits with their effects can alter protein, oil, palmitic, stearic, oleic, linoleic, and linolenic acids percentage in soybean seeds. The objective of this study was to identify Quantitative Trait Loci (QTL) controlling protein, oil, and fatty acids content in a set of F5:8 RILs de-rived from a cross between lines, ‘MD 96-5722’ and ‘Spencer’ using 5376 Single Nucleotide Polymorphism (SNP) markers from the Illumina Infinium SoySNP6K BeadChip array. …

Identifying Legal, Ecological And Governance Obstacles, And Opportunities For Adapting To Climate Change, Barbara Cosens

Articles

No abstract provided.

Adaptive Water Governance Project: Assessing Law, Resilience And Governance In Regional Socio-Ecological Water Systems Facing A Changing Climate, Barbara Cosens

Articles

No abstract provided.

Bastards! . . .. And The Welfare Plantation, Zanita E. Fenton

Articles

No abstract provided.

Experimental Design Of Photo-Fenton Reactions For The Treatment Of Car Wash Wastewater Effluents By Response Surface Methodological Analysis, Maha Tony, Zeinab Bedri

Articles

Establishing a treatment process for practical and economic disposal of car wash wastewater has become an urgent environmental concern. Photo-Fenton’s process as one of the advanced oxidation processes is a potentially useful oxidation process in treating such wastewater. Lab-scale experiments with UV source, coupled with Fenton’s reagent, showed that hydrocarbon oil is degradable through such a process. The feasibility of photo-Fenton’s process to treat wastewater from a car wash is investigated in the present study. A factorial design based on the response surface methodology was applied to optimize the photo-Fenton oxidation process conditions using chemical oxygen demand (COD) reduction as …