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Investigative Advocacy: The Mechanics Of Muckraking, Patrick Barry Jan 2022

Investigative Advocacy: The Mechanics Of Muckraking, Patrick Barry

Articles

This essay argues that drafting a complaint is a form of investigative advocacy and that the best of them uphold the tradition of muckraking journalism.


Platforms As Blackacres, Thomas E. Kadri Jan 2022

Platforms As Blackacres, Thomas E. Kadri

Articles

While writing this Article, I interviewed a journalist who writes stories about harmful technologies. To do this work, he gathers information from websites to reveal trends that online platforms would prefer to hide. His team has exposed how Facebook threatens people's privacy and safety, how Amazon hides cheaper deals from consumers, and how Google diverts political speech from our inboxes. You'd think the journalist might want credit for telling these important stories, but he instead insisted on anonymity when we talked because his lawyer was worried he'd be confessing to breaking the law-to committing the crime and tort of cyber-trespass. …


Accessible Design Is Mediated By Job Support Structures And Knowledge Gained Through Design Career Pathways, Sarah Andrew, Garreth W. Tigwell Jan 2022

Accessible Design Is Mediated By Job Support Structures And Knowledge Gained Through Design Career Pathways, Sarah Andrew, Garreth W. Tigwell

Articles

Digital designers often do not make their work accessible (e.g., websites failing criteria set by the W3C's Web Content Accessibility Guidelines), and accessible design research discusses many solutions to address this problem (e.g., teaching accessibility within university design and technical courses). However, prior research in this area typically does not acknowledge whether recommendations and resources to support accessible design are suitable for all digital designers due to different training pathways and job support structures (e.g., large-company vs. rural and self-employed designers or designers who learned their skills outside of formal education settings). We interviewed 20 digital designers from rural and …


The Landscape Of Startup Corporate Governance In The Founder-Friendly Era, Jennifer S. Fan Jan 2022

The Landscape Of Startup Corporate Governance In The Founder-Friendly Era, Jennifer S. Fan

Articles

In corporate governance scholarship, there is an important debate about the nature and roles of the members of the board of directors in venture capital-backed private companies. The impact of a newly emerged, founder-centric model has been underappreciated, while the role of the independent director as tiebreaker or swing vote is vastly overstated. The reality is that corporate governance in these companies is a norm-driven, consensus-building process that rarely spills out into open conflict.

This is the first empirical study of startup corporate governance post-Great Recession and during the pandemic. Using survey and interview methodologies, this Article makes four primary …


Terrified By Technology: How Systemic Bias Distorts U.S. Legal And Regulatory Responses To Emerging Technology, Steve Calandrillo, Nolan Kobuke Anderson Jan 2022

Terrified By Technology: How Systemic Bias Distorts U.S. Legal And Regulatory Responses To Emerging Technology, Steve Calandrillo, Nolan Kobuke Anderson

Articles

Americans are becoming increasingly aware of the systemic biases we possess and how those biases preclude us from collectively living out the true meaning of our national creed. But to fully understand systemic bias we must acknowledge that it is pervasive and extends beyond the contexts of race, privilege, and economic status. Understanding all forms of systemic bias helps us to better understand ourselves and our shortcomings. At first glance, a human bias against emerging technology caused by systemic risk misperception might seem uninteresting or unimportant. But this Article demonstrates how the presence of systemic bias anywhere, even in an …


Self-Control Of Personal Data And The Constitution In East Asia, Dongsheng Zang Jan 2022

Self-Control Of Personal Data And The Constitution In East Asia, Dongsheng Zang

Articles

No abstract provided.


The Supreme Court’S Chief Justice Of Intellectual Property Law, Bob Gomulkiewicz Jan 2022

The Supreme Court’S Chief Justice Of Intellectual Property Law, Bob Gomulkiewicz

Articles

Justice Clarence Thomas is one of the most recognizable members of the United States Supreme Court. Many people recall his stormy Senate confirmation hearing and notice his fiery dissenting opinions that call on the Court to reflect the original public meaning of the Constitution. Yet observers have missed one of Justice Thomas’s most significant contributions to the Court—his intellectual property law jurisprudence. Justice Thomas has authored more majority opinions in intellectual property cases than any other Justice in the Roberts Court era and now ranks as the most prolific author of patent law opinions in the history of the Supreme …


Designing Interdisciplinary, Early Intervention Dispute Resolution Tools To Decrease Evictions And Increase Housing Stability, Christine N. Cimini Jan 2022

Designing Interdisciplinary, Early Intervention Dispute Resolution Tools To Decrease Evictions And Increase Housing Stability, Christine N. Cimini

Articles

This Article provides a unique glimpse into the development of an early-intervention, pre-court, interdisciplinary dispute resolution project intended to decrease evictions and increase housing stability for recipients of subsidized housing in Seattle. With a grant from the Seattle Housing Authority (SHA), a coalition of non-profit organizations had the rare opportunity to design a dispute resolution system into existence. A dispute system design team was formed and began by examining the interconnected problems of housing instability, eviction, and houselessness. Despite thorough research on dispute system design and extensive meetings with stakeholders, the deign team encountered numerous challenges. This Article identifies the …


Bridges To A New Era Part 2: A Report On The Past, Present, And Potential Future Of Tribal Co-Management On Federal Lands In Alaska, Monte Mills, Martin Nie Jan 2022

Bridges To A New Era Part 2: A Report On The Past, Present, And Potential Future Of Tribal Co-Management On Federal Lands In Alaska, Monte Mills, Martin Nie

Articles

Nowhere else in the United States are tribal connections and reliance on federal public lands as deep and geographically broad-based as in what is now Alaska. The number of Tribes—229 federally recognized tribes—and the scope of the public land resource—nearly 223 million acres—are simply unparalleled. Across that massive landscape, federal public lands and the subsistence uses they provide remain, as they have been since time immemorial, “essential to Native physical, economic, traditional, and cultural existence.”[1] Alas, the institutions, systems, and processes responsible for managing those lands, protecting those uses, and honoring those connections are failing Alaska Native Tribes.

The …


The Hidden Harms Of Privacy Penalties, Mary D. Fan Jan 2022

The Hidden Harms Of Privacy Penalties, Mary D. Fan

Articles

How to frame privacy penalties to protect our personal information is an important question as demands for legislation and proposals proliferate. The predominant assumption in calls for a comprehensive consumer privacy regime is that regulation and penalties arm the consumer David against Goliath businesses. Missing in the focus on powerful companies is attention to the potential harms of expanding privacy penalties for small-fry individuals and entities, especially from disfavored or marginalized groups. This article is the first to illuminate the regressive risks of privacy penalties, showing how broad privacy penalties can become tools for harassment of small businesses and individuals …


Violence Everywhere: How The Current Spectacle Of Black Suffering, Police Violence, And The Violence Of Judicial Interpretation Undermine The Rule Of Law, David B. Owens Jan 2022

Violence Everywhere: How The Current Spectacle Of Black Suffering, Police Violence, And The Violence Of Judicial Interpretation Undermine The Rule Of Law, David B. Owens

Articles

No abstract provided.


Taxing Creativity, Xuan-Thao Nguyen, Jeffrey A. Maine Jan 2022

Taxing Creativity, Xuan-Thao Nguyen, Jeffrey A. Maine

Articles

The recent sell offs of song catalogs by Bob Dylan, Stevie Nicks, Neil Young, and Mick Fleetwood for extraordinarily large sums of money raise questions about the law on creativity. While patent and copyright laws encourage a wide array of creative endeavors, tax laws governing monetization of creative works do not. The Songwriters Capital Gains Equity Act, in particular, solidifies creativity exceptionalism, exacerbates tax inequities among creators, and perpetuates racial disparities in the tax Code. This Article asserts that the law must encourage creativity from all creators. It is time to eliminate tax exceptionalism for musical compositions or expand its …


The Injustice Of 1.5°C–2°C: The Need For A Scientifically Based Standard Of Fundamental Rights Protection In Constitutional Climate Change Cases, Andrea K. Rodgers, Lauren E. Sancken, Jennifer Marlow Jan 2022

The Injustice Of 1.5°C–2°C: The Need For A Scientifically Based Standard Of Fundamental Rights Protection In Constitutional Climate Change Cases, Andrea K. Rodgers, Lauren E. Sancken, Jennifer Marlow

Articles

In 2015, signatories to the Paris Agreement agreed to the goal of keeping global temperature rise this century to well below 2°C above preindustrial levels and to pursue efforts to limit the temperature increase even further to 1.5°C. Although the adoption of the Paris Agreement was in many ways a political triumph, seven years later many climate advocates are presenting the Paris target to judicial bodies as the de facto legal standard for fundamental rights protection in climate change cases. Yet, the history leading up to the signatories’ ultimate adoption of the Paris Agreement target suggests that the target is …


Modeling Through, Ryan Calo Jan 2022

Modeling Through, Ryan Calo

Articles

Theorists of justice have long imagined a decision-maker capable of acting wisely in every circumstance. Policymakers seldom live up to this ideal. They face well-understood limits, including an inability to anticipate the societal impacts of state intervention along a range of dimensions and values. Policymakers cannot see around corners or address societal problems at their roots. When it comes to regulation and policy-setting, policymakers are often forced, in the memorable words of political economist Charles Lindblom, to “muddle through” as best they can.

Powerful new affordances, from supercomputing to artificial intelligence, have arisen in the decades since Lindblom’s 1959 article …


Airborne Fungal Spore Review, New Advances And Automatisation, Moisés Martínez-Bracero, Emma Markey, Jerry Hourihane Clancy, Eoin Mcgillicuddy, Gavin Sewell, David J. O'Connor Jan 2022

Airborne Fungal Spore Review, New Advances And Automatisation, Moisés Martínez-Bracero, Emma Markey, Jerry Hourihane Clancy, Eoin Mcgillicuddy, Gavin Sewell, David J. O'Connor

Articles

Fungal spores make up a significant portion of Primary Biological Aerosol Particles (PBAPs) with large quantities of such particles noted in the air. Fungal particles are of interest because of their potential to affect the health of both plants and humans. They are omnipresent in the atmosphere year-round, with concentrations varying due to meteorological parameters and location. Equally, differences between indoor and outdoor fungal spore concentrations and dispersal play an important role in occupational health. This review attempts to summarise the different spore sampling methods, identify the most important spore types in terms of negative effects on crops and the …


Impacts Of Covid-19 Lockdown On Private Domestic Groundwater Sample Numbers, E. Coli Presence And E. Coli Concentration Across Ontario, January 2020–March 2021: An Interrupted Time-Series Analysis, T. Latchmore, S. Lavallee, Martin Boudou, K. Mcdermott, R. S. Brown, Paul Hynds, Anna Majury Jan 2022

Impacts Of Covid-19 Lockdown On Private Domestic Groundwater Sample Numbers, E. Coli Presence And E. Coli Concentration Across Ontario, January 2020–March 2021: An Interrupted Time-Series Analysis, T. Latchmore, S. Lavallee, Martin Boudou, K. Mcdermott, R. S. Brown, Paul Hynds, Anna Majury

Articles

Approximately 1.5 million individuals in Ontario are supplied by private water wells (private groundwater supplies). Unlike municipal supplies, private well water quality remains unregulated, with owners responsible for testing, treating, and maintaining their own water supplies. The COVID-19 global pandemic and associated non-pharmaceutical interventions (NPIs) have impacted many environmental (e.g., surface water and air quality) and human (e.g., healthcare, transportation) systems over the past 15-months (January 2020 to March 2021). To date, the impact of these interventions on private groundwater systems remains largely unknown. Accordingly, the current study aimed to investigate the impact of a province-wide COVID-19 lockdown (late-March 2020) …


Building Performance - Societal Drive, Programme And Symposium, Joseph Little, Patrick Daly Jan 2022

Building Performance - Societal Drive, Programme And Symposium, Joseph Little, Patrick Daly

Articles

Society is increasingly looking at the construction industry to mitigate the environmental crisis and solve the housing crisis through wholesale embrace of three broad sets of challenges. The MSc in Building Performance (Energy Efficiency in Design) (MSc BP(EED)) was created in 2017 to provide significant upskilling in the knowledge, skills, and software applications of building design professionals so that they can meet these challenges, while creating compliant, sustainable, super-low energy, new and renovated buildings. The delivery of the programme supports upskilling of employed building design professionals at Masters level, encouraging a minority to develop their capacity and interest in research …


Bioactive Peptides From Algae: Traditional And Novel Generation Strategies, Structure-Function Relationships, And Bioinformatics As Predictive Tools For Bioactivity, Jack O'Connor, Marco Garcia-Vaquero, Steve Meaney, Brijesh Kumar Tiwari Jan 2022

Bioactive Peptides From Algae: Traditional And Novel Generation Strategies, Structure-Function Relationships, And Bioinformatics As Predictive Tools For Bioactivity, Jack O'Connor, Marco Garcia-Vaquero, Steve Meaney, Brijesh Kumar Tiwari

Articles

Over the last decade, algae have been explored as alternative and sustainable protein sources for a balanced diet and more recently, as a potential source of algal-derived bioactive peptides with potential health benefits. This review will focus on the emerging processes for the generation and isolation of bioactive peptides or cryptides from algae, including: (1) pre-treatments of algae for the extraction of protein by physical and biochemical methods; and (2) methods for the generation of bioactive including enzymatic hydrolysis and other emerging methods. To date, the main biological properties of the peptides identified from algae, including anti-hypertensive, antioxidant and antiproliferative/ …


Charge Transfer Mediated Triplet Excited State Formation In Donor-Acceptor-Donor Bodipy: Application For Recording Of Holographic Structures In Photopolymerizable Glass, Tatsiana Mikulchyk, Safakath Karuthedath, Catherine S.P. De Castro, Andrey A. Buglak, Aimee Sheehan, Aaron Wieder, FréDéRic Laquai, Izabela Naydenova, Mikhail Filatov Jan 2022

Charge Transfer Mediated Triplet Excited State Formation In Donor-Acceptor-Donor Bodipy: Application For Recording Of Holographic Structures In Photopolymerizable Glass, Tatsiana Mikulchyk, Safakath Karuthedath, Catherine S.P. De Castro, Andrey A. Buglak, Aimee Sheehan, Aaron Wieder, FréDéRic Laquai, Izabela Naydenova, Mikhail Filatov

Articles

Donor–acceptor–donor BODIPY triads bearing anthracene or pyrene as electron donating subunits were prepared through a stepwise synthesis. Photoinduced electron transfer and formation of long-lived triplet excited states via spin–orbit charge transfer intersystem crossing (SOCT-ISC) was studied by steady-state and ultrafast pump-probe spectroscopy and further supported by DFT computations. New BODIPYs were found to form triplet states and sensitize singlet oxygen in both polar and non-polar solvents which is unusual for photosensitizers operating via SOCT-ISC. BODIPY-anthracene triad (ABA) was used as a photosensitizer component in a photopolymerizable glass that was prepared by a four-step sol–gel process. ABA in combination with N …


Application Of Advanced Non-Linear Spectral Decomposition And Regression Methods For Spectroscopic Analysis Of Targeted And Non-Targeted Irradiation Effects In An In-Vitro Model, Ciara Slattery, Khanh Nguyen, Laura Shields, Isabel Vega Carrascal, Sean Singleton, Fiona Lyng, Brendan Mcclean, Aidan Meade Jan 2022

Application Of Advanced Non-Linear Spectral Decomposition And Regression Methods For Spectroscopic Analysis Of Targeted And Non-Targeted Irradiation Effects In An In-Vitro Model, Ciara Slattery, Khanh Nguyen, Laura Shields, Isabel Vega Carrascal, Sean Singleton, Fiona Lyng, Brendan Mcclean, Aidan Meade

Articles

Irradiation of the tumour site during treatment for cancer with external-beam ionising radiation results in a complex and dynamic series of effects in both the tumour itself and the normal tissue which surrounds it. The development of a spectral model of the effect of each exposure and interaction mode between these tissues would enable label free assessment of the effect of radiotherapeutic treatment in practice. In this study Fourier transform Infrared microspectroscopic imaging was employed to analyse an in-vitro model of radiotherapeutic treatment for prostate cancer, in which a normal cell line (PNT1A) was exposed to low-dose X-ray radiation from …


Biomolecular Corona Stability In Association With Plasma Cholesterol Level, Duong N. Trinh, Meda Radlinskaite, Jack Cheeseman, Gunther Kuhnle, Helen M.I. Osborn, Paula Meleady, Daniel I.R. Spencer, Marco P. Monopoli Jan 2022

Biomolecular Corona Stability In Association With Plasma Cholesterol Level, Duong N. Trinh, Meda Radlinskaite, Jack Cheeseman, Gunther Kuhnle, Helen M.I. Osborn, Paula Meleady, Daniel I.R. Spencer, Marco P. Monopoli

Articles

Biomolecular corona is spontaneously formed on the surface of nanoparticles (NPs) when they are in contact with biological fluids. It plays an important role in the colloidal stability of NPs, which is of importance for most of their medical applications and toxicity assessment. While typical studies use either blood plasma or serum from a pooled biobank, it is unclear whether differences in the media, such as cholesterol level or protein concentration, might affect the NP colloidal stability and corona composition. In this study, the silica corona was prepared at particularly low plasma concentrations (3%, v/v–1.98 mg/mL) to identify the critical …


Spontaneous Symmetry Breaking And Linear Electrooptic Response In The Achiral Ferronematic Compound, Neelam Yadav, Yuri Panarin, Wanhe Jiang, Georg H. Mehl, J.K. Vij Jan 2022

Spontaneous Symmetry Breaking And Linear Electrooptic Response In The Achiral Ferronematic Compound, Neelam Yadav, Yuri Panarin, Wanhe Jiang, Georg H. Mehl, J.K. Vij

Articles

A compound with the constituent non-chiral molecules, DIO, known to exhibit three nematic subphases namely N, Nx and NF, is studied by polarizing microscopy as function of the alignment layers on one of the substrates, no alignment on any of the substrates, alignment layer on both substrates with parallel and antiparallel rubbing, different cell spacings. The cell with one alignment layer is also studied by electro-optics. N is found to be a conventional nematic phase, but it shows two additional unusual features: chiral domains of opposite chirality and the linear EO response to the applied signal under certain experimental conditions. …


Formation Of Gold Nanoparticle Self-Assembling Films In Various Polymer Matrices For Sers Substrates, Ksenia A. Maleeva, Ilia E. Kaliya, Anton P. Tkach, Anton A. Babaev, Michail Baranov, Kevin Berwick, Tatiana S. Perova, Alexander V. Baranov, Kirill V. Bogdanov Jan 2022

Formation Of Gold Nanoparticle Self-Assembling Films In Various Polymer Matrices For Sers Substrates, Ksenia A. Maleeva, Ilia E. Kaliya, Anton P. Tkach, Anton A. Babaev, Michail Baranov, Kevin Berwick, Tatiana S. Perova, Alexander V. Baranov, Kirill V. Bogdanov

Articles

Surface-enhanced Raman spectroscopy (SERS) is regarded as a versatile tool for studying the composition and structure of matter. This work has studied the preparation of a SERS substrate based on a self-assembling plasmonic nanoparticle film (SPF) in a polymer matrix. Several synthesis parameters for the SPF are investigated, including the size of the particles making up the film and the concentration and type of the self-assembling agent. The result of testing systems with different characteristics is discussed using a model substance (pseudo isocyaniniodide). These models can be useful in the study of biology and chemistry. Research results contain the optimal …


Application Of High-Intensity Ultrasound To Improve Food Processing Efficiency: A Review, Prasad Chavan, Pallavi Sharma, Sajeev Rattan Sharma, Tarsem Chand Mittal, Amit Jaiswal Jan 2022

Application Of High-Intensity Ultrasound To Improve Food Processing Efficiency: A Review, Prasad Chavan, Pallavi Sharma, Sajeev Rattan Sharma, Tarsem Chand Mittal, Amit Jaiswal

Articles

The use of non-thermal processing technologies has grown in response to an ever-increasing demand for high-quality, convenient meals with natural taste and flavour that are free of chemical additions and preservatives. Food processing plays a crucial role in addressing food security issues by reducing loss and controlling spoilage. Among the several non-thermal processing methods, ultrasound technology has shown to be very beneficial. Ultrasound processing, whether used alone or in combination with other methods, improves food quality significantly and is thus considered beneficial. Cutting, freezing, drying, homogenization, foaming and defoaming, filtration, emulsification, and extraction are just a few of the applications …


Opportunities And Barriers Faced By Early-Career Civil Engineers Enacting Global Responsibility, Shannon Chance, Inês Direito, John Mitchell Jan 2022

Opportunities And Barriers Faced By Early-Career Civil Engineers Enacting Global Responsibility, Shannon Chance, Inês Direito, John Mitchell

Articles

The term ‘global responsibility’ projects a holistic sense of ethics, sustainability, and obligation. To achieve the long-term viability of human life on Earth, civil engineering must be conducted in increasingly responsible ways, and civil engineers must value and enact global responsibility in their work. Interviews conducted with nine civil engineers in London provide insight regarding engineers’ familiarity with the term, how they learned about it, what opportunities and barriers they face, and what might be done by professional and educational institutions to help them practice more responsibly. Results indicate: the term itself is novel but underlying concepts are not; continuing …


A Magnetic Nanoparticle-Doped Photopolymer For Holographic Recording, Muhammad Irfan, Suzanne Martin, Muhammad Ahmed Obeidi, Scott Miller, Frank Kuster, Dermot Brabazon, Izabela Naydenova Jan 2022

A Magnetic Nanoparticle-Doped Photopolymer For Holographic Recording, Muhammad Irfan, Suzanne Martin, Muhammad Ahmed Obeidi, Scott Miller, Frank Kuster, Dermot Brabazon, Izabela Naydenova

Articles

Functionalised holograms are important for applications utilising smart diffractive optical elements for light redirection, shaping and in the development of sensors/indicators. This paper reports on holographic recording in novel magnetic nanocomposites and the observed temperature change in dry layers and liquid samples exposed to alternating magnetic field (AMF). The nanocomposite consists of N-isopropylacrylamide (NIPA)-based polymer doped with magnetic nanoparticles (MNPs), and local heating is achieved through magnetic induction. Here, volume transmission holographic gratings (VTHGs) are recorded with up to 24% diffraction efficiency (DE) in the dry layers of magnetic nanocomposites. The dry layers and liquid samples are then exposed to …


Perceived Social Support And Stress: A Study Of 1st Year Students In Ireland, Lavinia Mclean, David Gaul, Rebecca Penco Jan 2022

Perceived Social Support And Stress: A Study Of 1st Year Students In Ireland, Lavinia Mclean, David Gaul, Rebecca Penco

Articles

Social support is consistently associated with positive outcomes for students, in terms of wellbeing and academic achievement. For first year students, social support offers a way to deal with stressors associated with the challenge of transitioning to university. The current research was conducted with a range of first year students (n = 315) early in their first semester in university. Both male and female students reported moderate levels of social support and perceived stress, while those with higher levels of social support reported lower levels of stress. Gender differences were apparent in both the levels and sources of social …


A Micron-Range Displacement Sensor Based On Thermo-Optically Tuned Whispering Gallery Modes In A Microcapillary Resonator, Zhe Wang, Arun Kumar Mallik, Fangfang Wei, Zhuochen Wang, Anuradha Rout, Qiang Wu, Yuliya Semenova Jan 2022

A Micron-Range Displacement Sensor Based On Thermo-Optically Tuned Whispering Gallery Modes In A Microcapillary Resonator, Zhe Wang, Arun Kumar Mallik, Fangfang Wei, Zhuochen Wang, Anuradha Rout, Qiang Wu, Yuliya Semenova

Articles

A novel micron-range displacement sensor based on a whispering-gallery mode (WGM) microcapillary resonator filled with a ne matic liquid crystal (LC) and a magnetic nanoparticle- coated fiber half-taper is proposed and experimentally demonstrated. In the proposed device, the tip of a fiber half-taper coated with a thin layer of magnetic nanoparticles (MNPs) moves inside the LC-filled microcapillary resonator along its axis. The input end of the fiber half-taper is connected to a pump laser source and due to the thermo-optic effect within the MNPs, the fiber tip acts as point heat source increasing the temperature of the LC material in …


Comparison Study Of An Optimized Ultrasound-Based Method Versus An Optimized Conventional Method For Agar Extraction, And Protein Co-Extraction, From Gelidium Sesquipedale, Laura Pilar Gomez Barrio, Eduarda Melo Cabral, Ming Zhao, Carlos Alvarez Garcia, Ramsankar Senthamaraikannan, Ramesh Babu Padamati, Uma Tiwari, James Curtin, Brijesh K. Tiwari Jan 2022

Comparison Study Of An Optimized Ultrasound-Based Method Versus An Optimized Conventional Method For Agar Extraction, And Protein Co-Extraction, From Gelidium Sesquipedale, Laura Pilar Gomez Barrio, Eduarda Melo Cabral, Ming Zhao, Carlos Alvarez Garcia, Ramsankar Senthamaraikannan, Ramesh Babu Padamati, Uma Tiwari, James Curtin, Brijesh K. Tiwari

Articles

Agar is a hydrocolloid found in red seaweeds, which has been of industrial interest over the last century due to its multiple applications in the food, cosmetic, and medical fields. This polysaccharide, extracted by boiling for several hours, is released from the cell wall of red seaweeds. However, the environmental impact coming from the long processing time and the energy required to reach the targeted processing temperature needs to be reduced. In this study, a response surface methodology was employed to optimize both conventional extraction and ultrasound-assisted extractions. Two different models were successfully obtained (R2 = 0.8773 and R …


Cell Death Induced In Glioblastoma Cells By Plasma-Activated-Liquids (Pal) Is Primarily Mediated By Membrane Lipid Peroxidation And Not Ros Influx, Sebnem Gunes, Zhonglei He, Evanthia Tsoukou, Sing Wei Ng, Daniela Boehm, Beatriz Pinheiro, Paula Bourke, Renee Malone, Patrick J. Cullen, Wenxin Wang, James Curtin Jan 2022

Cell Death Induced In Glioblastoma Cells By Plasma-Activated-Liquids (Pal) Is Primarily Mediated By Membrane Lipid Peroxidation And Not Ros Influx, Sebnem Gunes, Zhonglei He, Evanthia Tsoukou, Sing Wei Ng, Daniela Boehm, Beatriz Pinheiro, Paula Bourke, Renee Malone, Patrick J. Cullen, Wenxin Wang, James Curtin

Articles

Since first identified in 1879, plasma, the fourth state of matter, has been developed and utilised in many fields. Nonthermal atmospheric plasma, also known as cold plasma, can be applied to liquids, where plasma reactive species such as reactive Oxygen and Nitrogen species and their effects can be retained and mediated through plasma-activated liquids (PAL). In the medical field, PAL is considered promising for wound treatment, sterilisation and cancer therapy due to its rich and relatively long-lived reactive species components. This study sought to identify any potential antagonistic effect between antioxidative intracellularly accumulated platinum nanoparticles (PtNPs) and PAL. We found …