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Controlling Unequal Surface Energy Results Caused By Test Liquids: The Case Of Uv/O3 Treated Pet, Bilge N. Altay, Paul D. Fleming, Md Arifur Rahman, Alexandra Pekarovicova, Bruce Myers, Cem Aydemir, Arif Karademir Apr 2022

Controlling Unequal Surface Energy Results Caused By Test Liquids: The Case Of Uv/O3 Treated Pet, Bilge N. Altay, Paul D. Fleming, Md Arifur Rahman, Alexandra Pekarovicova, Bruce Myers, Cem Aydemir, Arif Karademir

Articles

Ultraviolet/ozone (UV/O3) treatment has been reported to be an effective method to modify properties such as wettability, adhesion or adsorption of plastic surfaces. The change in the surface is measured by contact angle analysis, which employs liquids and their surface tensions (ST) to estimate the surface energy (SE). We found two different practices in the scientific community: (1) the majority of researchers adopted the ST value of liquids from the literature, while (2) other researchers conducted real-time measurements in the lab under ambient conditions prior to SE estimation. To the best of our knowledge, there is no study that compares …


Controlling Unequal Surface Energy Results Caused By Test Liquids: The Case Of Uv/O3 Treated Pet, Bilge N. Altay, Paul D. Fleming, Md Arifur Rahman, Alexandra Pekarovicova, Bruce Myers, Cem Aydemir, Arif Karademir Apr 2022

Controlling Unequal Surface Energy Results Caused By Test Liquids: The Case Of Uv/O3 Treated Pet, Bilge N. Altay, Paul D. Fleming, Md Arifur Rahman, Alexandra Pekarovicova, Bruce Myers, Cem Aydemir, Arif Karademir

Articles

Ultraviolet/ozone (UV/O3) treatment has been reported to be an effective method to modify properties such as wettability, adhesion or adsorption of plastic surfaces. The change in the surface is measured by contact angle analysis, which employs liquids and their surface tensions (ST) to estimate the surface energy (SE). We found two different practices in the scientific community: (1) the majority of researchers adopted the ST value of liquids from the literature, while (2) other researchers conducted real-time measurements in the lab under ambient conditions prior to SE estimation. To the best of our knowledge, there is no study that compares …


The World Is Our Classroom: Developing A Model For International Virtual Internships - The Global Innovations Project, Paul Doyle, Brian Keegan, Damian Gordon, Anna Becevel, Paul J. Gibson, Zhiying Jiang Phd, Dympna O'Sullivan Apr 2022

The World Is Our Classroom: Developing A Model For International Virtual Internships - The Global Innovations Project, Paul Doyle, Brian Keegan, Damian Gordon, Anna Becevel, Paul J. Gibson, Zhiying Jiang Phd, Dympna O'Sullivan

Articles

In the aftermath of COVID-19, remote working has become the norm, and graduates now need an even wider range of skills, which traditional classrooms and internships do not always provide. Working in multiple time zones, within global multi-cultural teams, and only ever meeting colleagues through online technology are just some of the challenges, which require a new type of global graduate. Transversal skills including leadership, collaboration, innovation, digital, green, organization and communication skills are critical. The disruption from COVID-19 also presents unprecedented opportunities to develop more inclusive approaches to internships and international experiences, to level the playing field for students …


Latin American Film, Mirna Vohnsen Apr 2022

Latin American Film, Mirna Vohnsen

Articles

The scholarship on Latin American film in 2020 points to a diverse and vibrant field of study that encompasses a wide range of themes. This year, the representations of indigenous peoples, as well as the studies on youth and transnationalism, have caught the attention of several scholars. Another topic that has gained importance is the revisiting of films, filmmakers, and performers from the twentieth century. Volume 17, number 2, of Studies in Spanish & Latin American Cinemas, which is devoted to Mexican documentaries from the last century, is a poignant example of this development. Aside from these topics, gender and …


In The Garden: Capacities That Contribute To Community Groups Establishing Community Gardens,, Gerard Doyle Apr 2022

In The Garden: Capacities That Contribute To Community Groups Establishing Community Gardens,, Gerard Doyle

Articles

Based on case studies in Dublin, Ireland, this paper examines the motives for individuals to establish community gardens therein. The paper also outlines the capacities required for community groups to successfully establish and sustain community gardens in Ireland. These capacities include the involvement of individuals with a range of expertise, the presence of supportive community groups/organisations and state agencies, and access to resources, including land. The research findings, detailed in this paper, indicate that community gardens in urban settings encounter a number of challenges, including the absence of a mechanism for community groups to access land. The article provides a …


The Power Of A Good Story: How Narrative Techniques Can Make Transactional Documents More Persuasive, Karen J. Sneddon Apr 2022

The Power Of A Good Story: How Narrative Techniques Can Make Transactional Documents More Persuasive, Karen J. Sneddon

Articles

Transactional documents are complex, multi-faceted documents reviewed by various audiences at multiple points in time. They are more than descriptive legal devices that dictate the exchange of widgets for cash. While the core of many transactional documents will be the acquisition, creation, or exchange of property or services, transactional documents do more than memorialize that understanding. At first glance, transactional documents may seem simply like expository texts that aim to create the private law between the transacting parties and educate the audience by delivering a sequence of instructions, but transactional documents do much more. They tell the stories of the …


Autonomous Vehicle Regulation & Trust: The Impact Of Failures To Comply With Standards, William H. Widen, Phillip Koopman Apr 2022

Autonomous Vehicle Regulation & Trust: The Impact Of Failures To Comply With Standards, William H. Widen, Phillip Koopman

Articles

The autonomous vehicle (AV) industry works very hard to create public trust in both AV technology and its developers. Building trust is part of a strategy to permit the industry itself to manage the testing and deployment of AV technology without regulatory interference. This article explains how industry actions to promote trust (both individually and collectively) have created concerns rather than comfort with this emerging technology. The article suggests how the industry might change its current approach to law and regulation from an adversarial posture to a more cooperative one in which a space is created for government regulation consistent …


Inoculating The Next Generation Of Lawyers: Mandating Substances Use And Mental Health Education For Law Students, Janet Stearns Apr 2022

Inoculating The Next Generation Of Lawyers: Mandating Substances Use And Mental Health Education For Law Students, Janet Stearns

Articles

No abstract provided.


Ai Insurance: How Liability Insurance Can Drive The Responsible Adoption Of Artificial Intelligence In Health Care, Ariel Dora Stern, Avi Goldfarb, Timo Minssen, W. Nicholson Price Ii Apr 2022

Ai Insurance: How Liability Insurance Can Drive The Responsible Adoption Of Artificial Intelligence In Health Care, Ariel Dora Stern, Avi Goldfarb, Timo Minssen, W. Nicholson Price Ii

Articles

Despite enthusiasm about the potential to apply artificial intelligence (AI) to medicine and health care delivery, adoption remains tepid, even for the most compelling technologies. In this article, the authors focus on one set of challenges to AI adoption: those related to liability. Well-designed AI liability insurance can mitigate predictable liability risks and uncertainties in a way that is aligned with the interests of health care’s main stakeholders, including patients, physicians, and health care organization leadership. A market for AI insurance will encourage the use of high-quality AI, because insurers will be most keen to underwrite those products that are …


Portraits Of Bankruptcy Filers, Pamela Foohey, Robert M. Lawless, Deborah Thorne Apr 2022

Portraits Of Bankruptcy Filers, Pamela Foohey, Robert M. Lawless, Deborah Thorne

Articles

One in ten adult Americans has turned to the consumer bankruptcy system for help. For almost forty years, the only systematic data collection about the people who file bankruptcy has come from the Consumer Bankruptcy Project (CBP), for which we serve as co-principal investigators. In this Article, we use CBP data from 2013 to 2019 to describe who is using the bankruptcy system, providing the first comprehensive overview of bankruptcy filers in thirty years. We use principal component analysis to leverage these data to identify distinct groups of people who file bankruptcy. This technique allows us to situate the distinctions …


A New Framework For Digital Taxation, Reuven Avi-Yonah, Young Ran (Christine) Kim, Karen Sam Apr 2022

A New Framework For Digital Taxation, Reuven Avi-Yonah, Young Ran (Christine) Kim, Karen Sam

Articles

The international tax regime has wide implications for business, trade, and the international political economy. Under current law, multinational enterprises do not pay their fair share of taxes to market countries where profits are generated because market countries are only allowed to tax companies with a physical presence there. Digital companies, like Google and Amazon, can operate entirely online, thereby avoiding market country taxes. Multinationals can also exploit existing tax rules by shifting their profits to low-tax jurisdictions, thereby avoiding taxes in the residence country where their headquarters are located.

Recently, a global tax deal was reached to tackle these …


"A Mystifying And Distorting Factor": The Electoral College And American Democracy, Katherine A. Shaw Apr 2022

"A Mystifying And Distorting Factor": The Electoral College And American Democracy, Katherine A. Shaw

Articles

A Review of Let the People Pick the President: The Case for Abolishing the Electoral College. By Jesse Wegman.


The Progressive Love Affair With The Carceral State, Kate Levine Apr 2022

The Progressive Love Affair With The Carceral State, Kate Levine

Articles

A Review of The Feminist War on Crime: The Unexpected Role of Women’s Liberation in Mass Incarceration. By Aya Gruber.


Judicial Impartiality In The Judicial Council Act 2019: Challenges And Opportunities, Brian M. Barry Dr Mar 2022

Judicial Impartiality In The Judicial Council Act 2019: Challenges And Opportunities, Brian M. Barry Dr

Articles

The Judicial Council is tasked with promoting and maintaining high standards of judicial conduct. The Judicial Council Act 2019 identifies judicial impartiality as a principle of judicial conduct that Irish judges are required to uphold and exemplify. Despite its ubiquity, judicial impartiality is perhaps under-explained and under-examined.

This article considers the nature and scope of judicial impartiality in contemporary Irish judging. It argues that the Judicial Council ought to take a proactive, multi-faceted approach to promote and maintain judicial impartiality, to address contemporary challenges that the Irish judiciary face including increasingly sophisticated empirical research into judicial performance, the proliferation of …


Teaching Ethnographic Methods For Cultural Anthropology: Current Practices And Needed Innovation, Alissa Ruth, Katherine Mayfour, Thurka Sangaramoorthy, Bryan Mckinley Jones Brayboy, Melissa Beresford, Alexandra Brewis, H. Russell Bernard, Meskeren Z. Glegziabher, Jessica Hardin, Krista Harper, Pardis Mahdavi, Jeffrey G. Snodgrass, Cindi Sturtzsreetharan, Amber Wutich Mar 2022

Teaching Ethnographic Methods For Cultural Anthropology: Current Practices And Needed Innovation, Alissa Ruth, Katherine Mayfour, Thurka Sangaramoorthy, Bryan Mckinley Jones Brayboy, Melissa Beresford, Alexandra Brewis, H. Russell Bernard, Meskeren Z. Glegziabher, Jessica Hardin, Krista Harper, Pardis Mahdavi, Jeffrey G. Snodgrass, Cindi Sturtzsreetharan, Amber Wutich

Articles

Historically, ethnographic methods were learned by cultural anthropology students in individual research projects. This approach creates challenges for teaching in ways that respond to the next generation’s calls to decenter anthropology’s White, heteropatriarchal voices and engage in collaborative community-based research. Analyzing syllabi from 107 ethnographic methods training courses from the United States, we find the tradition of the “lone researcher” persists and is the basis of ethnographic training for the next generation. There is little evidence of either active reflection or team-based pedagogy, both identified as necessary to meet career opportunities and diversification goals for the wider field of cultural …


Acceptability-Based Brand Color Tolerance, A Case Study, Robert Chung, Yan Liu Mar 2022

Acceptability-Based Brand Color Tolerance, A Case Study, Robert Chung, Yan Liu

Articles

The Pantone R Formula Guide (or Guide), printed using specially-formulated inks on specified substrates, has been used widely by brands to specify brand color aims. While the Guide is silent on brand color tolerance, there are two competing criteria that influence the brand color tolerance, i.e., perceptibility and acceptability. Perceptibility-based color tolerance focuses on “Can I see the difference?” and the permissive difference is in the just-noticeable difference (JND) region. Acceptability-based color tolerance, focusing on “Can I accept the outcome?”, requires fit-for-use cases to identify what the just-acceptable difference (JAD) is. Instead of conducting psychometric tests, this research uses the …


An Analysis Of The Impact And Efficacy Of Online Emotional Intelligence Coaching As A Support Mechanism For University Students, Aiden Carthy, Wyndham Chalmers, Eoghan Guiry, Philip Owende Mar 2022

An Analysis Of The Impact And Efficacy Of Online Emotional Intelligence Coaching As A Support Mechanism For University Students, Aiden Carthy, Wyndham Chalmers, Eoghan Guiry, Philip Owende

Articles

As a consequence of the COVID-19 pandemic, many college courses have pivoted to complete online delivery and colleges are also tasked with providing student supports online. It is likely this transition will last beyond any COVID-19 specific restrictions, therefore this small-scale, exploratory study examined the efficacy and impact of the provision of a 5 week online emotional intelligence (EI) coaching programme to a cohort of Irish university students (n = 19) studying at Technological University Dublin (TU Dublin). Results revealed that the average overall level of EI increased for participants following the coaching programme. Students reported that they believed …


Assessment Of Consumer Protection Act 2019 To Support Tobacco Control In India, Ashok R. Patil Mar 2022

Assessment Of Consumer Protection Act 2019 To Support Tobacco Control In India, Ashok R. Patil

Articles

The use of tobacco products has been clearly established to cause significant medical and economic harm. While specific tobacco control legislation has been enacted in the form of the COTPA 2003, it is important to examine if other legislations can be utilised for regulation of tobacco consumption. One such legislation is the Consumer Protection Act 2019, which significantly expands the rights of consumers and protection given to them in terms of product safety and product quality. Accordingly, this paper provides an in-depth analysis of the Consumer Protection Act 2019 and the scope of utilising this legislation and the jurisprudence on …


Adapting To 4 Degrees C World, Karrigan Bork, Karen Bradshaw, Cinnamon P. Carlarne, Robin Kundis Craig, Sarah Fox, Josh Galperin, Keith Hirokawa, Shi-Ling Hsu, Katrina Kuh, Kevin Lynch, Michele Okoh, Jessica Owley, Melissa Powers, Shannon Roesler, J.B. Ruhl, James Salzman, David Takacs, Clifford J. Villa Mar 2022

Adapting To 4 Degrees C World, Karrigan Bork, Karen Bradshaw, Cinnamon P. Carlarne, Robin Kundis Craig, Sarah Fox, Josh Galperin, Keith Hirokawa, Shi-Ling Hsu, Katrina Kuh, Kevin Lynch, Michele Okoh, Jessica Owley, Melissa Powers, Shannon Roesler, J.B. Ruhl, James Salzman, David Takacs, Clifford J. Villa

Articles

The Paris Agreement's goal to hold warming to 1.50-2 0 C above pre-industrial levels now appears unrealistic. Profs. Robin Kundis Craig and J.B. Ruhl have recently argued that because a 40 C world may be likely, we must recognize the disruptive consequences of such a world and respond by reimagining governance structures to meet the challenges of adapting to it. In this latest in a biannual series of essays, they and other members of the Environmental Law Collaborative explore what 40 C might mean for a variety of current legal doctrines, planning policies, governance structures, and institutions.


Towards An Ethical Framework For The Design And Development Of Inclusive Home-Based Smart Technology For Smart Spaces For Older Adults And People With Disabilities, Emma Murphy, Julie Doyle, Ioannis Stavrakakis, Damian Gordon, Brian Keegan, Dympna O'Sullivan Feb 2022

Towards An Ethical Framework For The Design And Development Of Inclusive Home-Based Smart Technology For Smart Spaces For Older Adults And People With Disabilities, Emma Murphy, Julie Doyle, Ioannis Stavrakakis, Damian Gordon, Brian Keegan, Dympna O'Sullivan

Articles

Unique ethical, privacy and safety implications arise for people who are reliant on home-based smart technology due to health conditions or disabilities. As a result we need to carefully reflect on our approaches to ethical issues over the life cycle of smart home technology design and the wider living context for end users and relevant stakeholders. In this position paper we highlight a need for a reflective, inclusive ethical framework for the design of inclusive smart spaces. We present key ethical considerations in the design, development and deployment of smart home-based technology for older adults and people with disabilities. We …


Understanding The Influence Of Place On Festival Making And Artistic Production In The Local Urban Festival Context, Danielle Lynch, Bernadette Quinn Dr Feb 2022

Understanding The Influence Of Place On Festival Making And Artistic Production In The Local Urban Festival Context, Danielle Lynch, Bernadette Quinn Dr

Articles

Recent decades have seen a dramatic increase in research output on arts festivals and cultural events, and a growing focus on the role festivals play in negotiating and constructing meanings of place. However, little attention has been paid to how place shapes the process of festival making and artistic production. This paper attempts to address this shortcoming by examining the extent to which place matters to the production of festival activity and asks: how does place influence festival making and artistic production in a local arts festival context? The study is part of ongoing qualitative research into the Five Lamps …


Sociodemographic, Personal, Peer, And Familial Predictors Of E-Cigarette Ever Use In Espad Ireland: A Forward Stepwise Logistic Regression Model, Joan Hanafin, Salome Sunday, Luke Clancy Feb 2022

Sociodemographic, Personal, Peer, And Familial Predictors Of E-Cigarette Ever Use In Espad Ireland: A Forward Stepwise Logistic Regression Model, Joan Hanafin, Salome Sunday, Luke Clancy

Articles

Introduction:
/="/">E-cigarette ever use has risen significantly in recent years in Ireland, similar to trends elsewhere in Europe, the United States, and Asia-Pacific region. Results from ESPAD Ireland (European School Survey Project on Alcohol and other Drugs) show teenage e-cigarette ever use increased from 18% (2015) to 37% (2019). Given this increase, our aim is to profile e-cigarette ever users and never users in this age group; to examine sociodemographic, personal, peer, and familial factors associated with e-cigarette ever use; and to suggest appropriate measures to reduce use.
/="/">
/="/">Methods:
/="/">A nationally representative stratified random sample of …


Using Phreeqc To Model Cement Hydration, Niall Holmes Dr., Mark Tyrer, Roger P. West Prof, Aaron Lowe, Denis Kelliher Feb 2022

Using Phreeqc To Model Cement Hydration, Niall Holmes Dr., Mark Tyrer, Roger P. West Prof, Aaron Lowe, Denis Kelliher

Articles

This paper presents the steps involved in undertaking an analysis of hydrating cements with different levels of limestone powder using the PHREEQC geochemical software with the Notepad++ editor. The analysis begins with determining which solid phases are thermodynamically predicted to precipitate and form using the oxide compositions of commercial CEM I and CEM II/A-L cements. When the phases are known, PHREEQC is programmed to provide predictions of the phase dissolution and phase assemblage over time (here, 1000 days of hydration) as well as the pore solution chemistry. Thermodynamics has been successfully applied to the field of cement hydration to predict …


In Vitro Toxicological Evaluation Of Mesoporous Silica Microparticles Functionalised 1 With Carvacrol And Thymol, Cristina Fuentes, Ana Fuentes, Hugh Byrne, José Barat, María José Ruiz Feb 2022

In Vitro Toxicological Evaluation Of Mesoporous Silica Microparticles Functionalised 1 With Carvacrol And Thymol, Cristina Fuentes, Ana Fuentes, Hugh Byrne, José Barat, María José Ruiz

Articles

The cytotoxicity of carvacrol- and thymol- functionalised mesoporous silica microparticles (MCM-41) was assessed in the human hepatocarcinoma cell line (HepG2). Cell viability, lactate dehydrogenase (LDH) activity, reactive oxygen species (ROS) production, mitochondrial membrane potential (ΔΨm), lipid peroxidation (LPO) and apoptosis/necrosis analysis were used as endpoints. Results showed that both materials induced cytotoxicity in a time and concentration-dependent manner, being more cytotoxic than free essential oil components and bare MCM-41. This effect was caused by the cell-particle interactions and not from degradation products released to the culture media, as demonstrated in the extract dilution assays. LDH release was seen to be …


Extracellular Secretion Of A Cutinase With Polyester-Degrading Potential By E. Coli Using A Novel Signal Peptide From Amycolatopsis Mediterranei, Yeqi Tan, Gemma K. Kinsella, Gary T. Henehan, Barry J. Ryan Feb 2022

Extracellular Secretion Of A Cutinase With Polyester-Degrading Potential By E. Coli Using A Novel Signal Peptide From Amycolatopsis Mediterranei, Yeqi Tan, Gemma K. Kinsella, Gary T. Henehan, Barry J. Ryan

Articles

Recent studies in this laboratory showed that an extracellular cutinase from A. mediterranei (AmCut) was able to degrade the plastics polycaprolactone and polybutylene succinate. Such plastics can be slow to degrade in soils due to a lack of efficient polyester degrading organisms. AmCut also showed potential for the biocatalytic synthesis of esters by reverse hydrolysis.

The gene for AmCut has an upstream leader sequence whose transcript is not present in the purified enzyme. In this study, we show using predictive modelling, that this sequence codes for an N-terminal signal peptide that directs transmembrane expression via the Sec secretion pathway.

E. …


Effects Of Religiosity And Travel Desire On Covid-19 Vaccination Intentions, Muhammet Kesgin, Ali Selcuk Can, Dogan Gursoy, Yuksel Ekinci, Khaled Aldawodi Jan 2022

Effects Of Religiosity And Travel Desire On Covid-19 Vaccination Intentions, Muhammet Kesgin, Ali Selcuk Can, Dogan Gursoy, Yuksel Ekinci, Khaled Aldawodi

Articles

Despite the deadly consequences of the COVID-19 pandemic, vaccine hesitation remains a threat to public health and international travel. This study tests the effect of Muslim religiosity on belief-based attitudes (i.e., subjective norms, perceived behavioural control) and travel desire as a proxy for COVID-19 vaccination intentions. The structural model was tested using PLS-SEM with the data collected via a self-administrated survey between April and June 2021 in Saudi Arabia (N=759). Results reveal that travel desire along with belief-based attitudes influence COVID-19 vaccination intentions. Intrinsic religiosity influences individuals’ subjective norms, directly and perceived behavioural control and COVID-19 vaccination intentions indirectly through …


Ultrasound 96 Probe Device Protocol For Cancer Cell Treatment, Aisling Field, Brijesh K. Tiwari, James F. Curtin, Julie R M Mondala, Janith Wanigasekara Jan 2022

Ultrasound 96 Probe Device Protocol For Cancer Cell Treatment, Aisling Field, Brijesh K. Tiwari, James F. Curtin, Julie R M Mondala, Janith Wanigasekara

Articles

Ultrasound is a sound wave with frequencies ranging between 20 kHz and 20 MHz. Ultrasound is able to temporarily and repeatedly open the BBB safely and enhance chemotherapeutic delivery without adverse effects. This novel technique in drug delivery benefits from the powerful ability of ultrasound to produce cavitation activity. Cavitation is the generation and activity of gas-filled bubbles in a medium exposed to ultrasound. As the pressure wave passes through the media, gas bubbles expand at low pressure and contract at high pressure. This leads to oscillation which produces a circulating fluid flow known as microstreaming around the bubble with …


Evolutionary Paths To Macrolide Resistance In A Neisseria Commensal Converge On Ribosomal Genes Through Short Sequence Duplications, Jordan C. Raisman, Michael A. Fiore, Lucille Tomin, Joseph K. O. Adjei, Virginia X. Aswad, Jonathan Chu, Christina J. Domondon, Ben A. Donahue, Claudia A. Masciotti, Connor G. Mcgrath, Jo Melita, Paul A. Podbielski, Madelyn R. Schreiner, Lauren J. Trumpore, Peter C. Wengert, Emalee A. Wrightstone, André O. Hudson, Crista B. Wadsworth Jan 2022

Evolutionary Paths To Macrolide Resistance In A Neisseria Commensal Converge On Ribosomal Genes Through Short Sequence Duplications, Jordan C. Raisman, Michael A. Fiore, Lucille Tomin, Joseph K. O. Adjei, Virginia X. Aswad, Jonathan Chu, Christina J. Domondon, Ben A. Donahue, Claudia A. Masciotti, Connor G. Mcgrath, Jo Melita, Paul A. Podbielski, Madelyn R. Schreiner, Lauren J. Trumpore, Peter C. Wengert, Emalee A. Wrightstone, André O. Hudson, Crista B. Wadsworth

Articles

Neisseria commensals are an indisputable source of resistance for their pathogenic relatives. However, the evolutionary paths commensal species take to reduced susceptibility in this genus have been relatively underexplored. Here, we leverage in vitro selection as a powerful screen to identify the genetic adaptations that produce azithromycin resistance (� 2 μg/mL) in the Neisseria commensal, N. elongata. Across multiple lineages (n = 7/16), we find mutations that reduce susceptibility to azithromycin converge on the locus encoding the 50S ribosomal L34 protein (rpmH) and the intergenic region proximal to the 30S ribosomal S3 protein (rpsC) through short tandem duplication events. Interestingly, …


Re-Thinking The Coronavirus Pandemic As A Policy Punctuation: Covid-19 As A Path-Clearing Policy Accelerator, John Hogan, Michael Patrick Howlett, Mary P. Murphy Jan 2022

Re-Thinking The Coronavirus Pandemic As A Policy Punctuation: Covid-19 As A Path-Clearing Policy Accelerator, John Hogan, Michael Patrick Howlett, Mary P. Murphy

Articles

This article joins with others in this special issue to examine the evolution of our understanding of how the coronavirus disease (COVID)-19 pandemic impacted policy ideas and routines across a wide variety of sectors of government activity. Did policy ideas and routines transform as a result of the pandemic or were they merely a continuation of the status quo ante? If they did transform, are the transformations temporary in nature or likely to lead to significant, deep and permanent reform to existing policy paths and trajectories? As this article sets out, the literature on policy punctuations has evolved and helps …


Plasma Induced Reactive Oxygen Species-Dependent Cytotoxicity In Glioblastoma 3d Tumourspheres, Janith Wanigasekara, Carlos Barcia, Patrick J. Cullen, Brijesh Tiwari, James F. Curtin Jan 2022

Plasma Induced Reactive Oxygen Species-Dependent Cytotoxicity In Glioblastoma 3d Tumourspheres, Janith Wanigasekara, Carlos Barcia, Patrick J. Cullen, Brijesh Tiwari, James F. Curtin

Articles

The aim of this study was to determine the effects of a pin‐to‐plate cold atmospheric plasma (CAP) on U‐251 MG three‐dimensional (3D) glioblastoma spheroids under different conditions. 3D tumorspheres showed higher resistance to the CAP treatment compared to 2D monolayer cells. A single CAP treatment was able to induce cytotoxicity, while multiple CAP treatments augmented this effect. CAP was also able to induce cytotoxicity throughout the tumoursphere, and we identified that reactive oxygen species(ROS) plays a major role, while H2O2plays a partial role in CAP‐induced cytotoxicity in tumour-spheres. We conclude that ROS‐dependent cytotoxicity is induced uniformly throughout glioblastoma and epidermoid …