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Low Complexity Maximum-Likelihood Detector For Dsttd Architecture Based On The Qrd-M Algorithm, Joaquín Cortez, Miguel Bazdresch, Julio Ramírez, Ramón Palacio, Erica Ruiz

Articles

This paper presents a new decoder algorithm for the double space-time transmit diversity (DSTTD) system. The decoder is based on the QRD-M algorithm, which performs a breadth-first search of possible solutions tree. The search is simplified by skipping unlikely candididates, and it is stopped when no promising candidates are left. Furthermore, the search is divided into three concurrent iterations, making possible a fast, parallel implementation either in hardware or software. After presenting an analysis of the capacity and diversity of DSTTD, we present performance results showing that the proposed decoder is capable of achieving near maximum likelihood performance. We also …

A Community-Building Framework For Collaborative Research Coordination Across The Education And Biology Research Disciplines, Nancy Pelaez, Trevor R. Anderson, Stephanie M. Gardner, Yue Yin, Joel K. Abraham, Edward L. Bartlett, Cara Gormally, Carol A. Hurney, Tammy M. Long, Dina L. Newman, Karen Sirum, Michael T. Stevens

Articles

Since 2009, the U.S. National Science Foundation Directorate for Biological Sciences has funded Research Coordination Networks (RCN) aimed at collaborative efforts to improve participation, learning, and assessment in undergraduate biology education (UBE). RCN-UBE projects focus on coordination and communication among scientists and educators who are fostering improved and innovative approaches to biology education. When faculty members collaborate with the overarching goal of advancing undergraduate biology education, there is a need to optimize collaboration between participants in order to deeply integrate the knowledge across disciplinary boundaries. In this essay we propose a novel guiding framework for bringing colleagues together to advance …

Raman Spectral Analysis For Rapid Screening Of Dengue Infection, Tahir Mahmood, Haq Nawaz, A. Ditta, M.I. Majeed, M.A. Hanif, N. Rashid, H.N. Bhatti, H.F. Nargis, M. Saleem, Franck Bonnier, Hugh Byrne

Articles

Infection with the dengue virus is currently clinically detected according to different biomarkers in human blood plasma, commonly measured by enzyme linked immunosorbent assays, including non-structural proteins (Ns1), immunoglobulin M (IgM) and immunoglobulin G (IgG). However, there is little or no mutual correlation between the biomarkers, as demonstrated in this study by a comparison of their levels in samples from 17 patients. As an alternative, the label free, rapid screening technique, Raman spectroscopy has been used for the characterisation/diagnosis of healthy and dengue infected human blood plasma samples. In dengue positive samples, changes in specific Raman spectral bands associated with …

Parental Attitudes To Myopia: A Key Agent Of Change For Myopia Control?, Saoirse Mccrann, Daniel Ian Flitcroft, Kevin Lalor, John Butler, Aaron Bush, James Loughman

Articles

Purpose

With the increasing prevalence in myopia there is growing interest in active myopia prevention. This study aims to increase our understanding of parental attitudes to myopia development and control, as a means to inform future health planning and policy. It evaluates, for the first time, the attitude of parents to myopia and its associated risks, as well as assessing the exposure of Irish children to environmental factors that may influence their risk profile for myopia development.

Methods

Parents of 8–13 year old children in eight participating schools completed a questionnaire designed to assess their knowledge of and attitudes towards …

Controlling The Jury-Teaching Function, Richard D. Friedman

Articles

When evidence with a scientific basis is offered, two fundamental questions arise. First, should it be admitted? Second, if so, how should it be assessed? There are numerous participants who might play a role in deciding these questions—the jury (on the second question only), the parties (through counsel), expert witnesses on each side, the trial court, the forces controlling the judicial system (which include, but are not limited to, the appellate courts), and the scientific establishment. In this Article, I will suggest that together, the last two—the forces controlling the judicial system and the scientific establishment—have a large role to …

Endoscopic Ultrasound Features Of Multiple Endocrine Neoplasia Type 1-Related Versus Sporadic Pancreatic Neuroendocrine Tumors: A Single-Center Retrospective Study, Gianluca Tamagno, Vanessa Scherer, Alberto Caimo, Simona Bergmann, Peter Kann

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Pancreatic neuroendocrine tumors (pNETs) can occur in patients with a familial syndrome either as multiple endocrine neoplasia type 1 (MEN-1) or as sporadic tumors. Endoscopic ultrasound (EUS) has become one of the first-line investigations for pNET characterization. The ultrasonographic features of pNETs may differ depending on the familial versus sporadic pathogenesis of the tumor. Therefore, the EUS findings could help and direct the definition of a pNET with an impact on the most appropriate diagnostic and ther- apeutic patient management. Methods: In this single-center retrospective study, we reviewed the EUS features of 94 pNETs from 37 MEN-1 patients and 15 …

Conformational Studies Of Gram-Negative Bacterial Quorum Sensing Acyl Homoserine Lactone (Ahl) Molecules: The Importance Of The N→* Interaction, Fintan Kelleher, Goar Sánchez-Sanz, Darren Crowe, Alan Nicholson, Adrienne Fleming

Articles

A ¹H NMR study shows the presence of intermolecular hydrogen bonds for AHLs in CDCl₃ solution. A detailed computational study of the structure of AHLs and the relative stability between the extended conformations (X) and those showing n→p* interactions (np) have been carried out by means of DFT calculations. Solvent effects have been shown to be very important when stabilising np conformations, particularly with polar solvents. This was shown by the shortening of C···O intramolecular distances and the increase in the relative energies favouring the np conformation with the dielectric constant of the solvent. …

Enzymatic Extraction Of Fucoxanthin From Brown Seaweeds, Emer Shannon, Nissreen Abu-Ghannam

Articles

Brown seaweeds contain a number of bioactive compounds. The xanthophyll, fucoxanthin, has in vivo efficacy against disorders such as type 2 diabetes, obesity and cancer. Organic solvents are traditionally employed to extract fucoxanthin, but carry a toxic chemical and environmental burden. The aim of this study was to optimise a fucoxanthin extraction method using enzymes, water, low-temperature dehydration and mechanical blending, to produce yields comparable to those achieved with an organic solvent (acetone). Response surface methodology was applied, using Fucus vesiculosus as a model species. A fucoxanthin yield of 0.657 mg g^-1 (dry mass) was obtained from F. …

Holographic Beam-Shaping Diffractive Diffusers Fabricated By Using Controlled Laser Speckle, Kevin Murphy, Vincent Toal, Izabela Naydenova, Suzanne Martin

Articles

A method for fabricating diffractive holographic optical diffusers is reported, allowing a high degree of control of the resulting diffuser characteristics. The method consists of recording a laser speckle pattern using a single carrier beam, with controlled speckle size and shape, in an acrylamide-based volume photopolymer. The multiple interferences that create the speckle pattern form the hologram. Results are presented verifying the diffusers are volume holographic in nature and the speckle pattern is recorded accurately in the photopolymer. Diffusers recorded by this method are analysed to characterise the optical performance of the diffusers and to illustrate their beam-shaping capabilities, particularly …

Quantifying Partisan Gerrymandering: An Evaluation Of The Efficiency Gap Proposal, Benjamin Plener Cover

Articles

Electoral districting presents a risk of partisan gerrymandering: the manipulation of electoral boundaries to favor one political party over another. For three decades, the U.S. Supreme Court has failed to settle on a legal test for partisan gerrymandering, and such claims have uniformly failed. Until recently. Plaintiffs prevailed before a three-judge federal panel in Wisconsin by leveraging a new measure called the "efficiency gap," which quantifies partisan gerrymandering in terms of two parties' relative efficiency at translating votes for their party into seats in government. The case is now before the Court, which may embrace the efficiency gap approach and …

Angular Lens, Rishabh Sahu, Swati Chaudhary, Kedar Khare, Mishkatul Bhattacharya, Harshawardhan Wanare, Anand K. Jha

Articles

We propose a single phase-only optical element that transforms different orbital angular momentum (OAM) modes into localized spots at separated angular positions on a transverse plane. We refer to this element as an angular lens since it separates out OAM modes in a manner analogous to how a converging lens separates out transverse wave-vector modes at the focal plane. We also simulate the proposed angular lens using a spatial light modulator and experimentally demonstrate its working. Our work can have important implications for OAM-based classical and quantum communication applications.

Interdisciplinary Teaching And Learning Within Molecular Gastronomy Education: Does It Benefit Students?, Roisin Burke, Pauline Danaher

Articles

Since the creation of Molecular Gastronomy (MG) as a scientific discipline in 1988 a variety of higher education modules and programmes in that discipline have developed around the world. At the Technological University Dublin, MG has been taught using an interdisciplinary approach since the academic year 2012/2013. A Culinary Science lecturer and a Culinary Arts lecturer work in synergy and teach an interdisciplinary group of Food Science (FS) and Culinary Arts (CA) students. The students’ work is assessed, in each academic year, using summative methods i.e. written exam and a project assignment. In the academic year 2016/2017 the assignment reports …

Investigating Secondary Students Beliefs About Mathematical Problem-Solving, Mark Prendergast, Cormac Breen, Aibhin Bray, Fiona Faulkner, Brian Carroll, Dominic Quinn

Articles

Many studies over the past thirty years have highlighted the important role of students’ beliefs for successful problem solving in mathematics. Given the recent emphasis afforded to problem solving on the reformed Irish secondary school mathematics curriculum, the main aim of this study was to identify Irish students’ (n = 975) beliefs about the field. A quantitative measure of these beliefs was attained through the use of the Indiana Mathematical Belief Scale, an existing thirty item (five scale) self-report questionnaire. A statistical analysis of the data revealed that students who were further through their secondary education had a stronger belief …

In Vitro Label Free Screening Of Chemotherapeutic Drugs Using Raman Micro-Spectroscopy: Towards A New Paradigm Of Spectralomics., Zeineb Farhane, Haq Nawaz, Franck Bonnier, Hugh Byrne

Articles

This overview groups some of the recent studies highlighting the potential application of Raman micro-spectroscopy as an analytical technique in preclinical development to predict drug mechanism of action and in clinical application as a companion diagnostic and in personalised therapy due to its capacity to predict cellular resistance and therefore to optimise chemotherapeutic treatment efficacy.

Notably, the anthracyclines, Doxorubicin and Actinomycin D, elicit similar spectroscopic signatures of subcellular interaction characteristic of the mode of action of intercalation. Although Cisplatin and Vincristine show markedly different signatures, at low exposure doses, their signatures at higher doses show marked similarities to those elicited …

Confocal Raman Spectroscopic Imaging For In Vitro Monitoring Of Active Ingredient Penetration And Distribution In Reconstructed Human Epidermis Model, Lynda Miloudi, Franck Bonnier, Ali Tfayli, Florent Yvergnaux, Hugh Byrne, Igor Chourpa, Emilie Munnier

Articles

Topically applied Active Cosmetic Ingredients (ACI) or Active Pharmaceutical Ingredients (API) efficacy is directly related to their efficiency of penetration in the skin. In vitro Reconstructed Human Epidermis (RHE) surrogate models offer in vivo like skin samples for transdermal studies. Using Delipidol®, an ACI currently used in the cosmetics industry, the capabilities to deliver accurate distribution maps and penetration profiles of this molecule by means of Confocal Raman spectroscopic Imaging have been demonstrated. Using a NCLS (Non negative constrained least squares) approach, contribution of specific molecules can be estimated at each point of spectral maps in order to deliver semi-quantitative …

Studies Of Geometrical Profiling In Fabricated Tapered Optical Fbers Using Whispering Gallery Modes Spectroscopy, Vishnu Kavungal, Gerald Farrell, Qiang Wu, Arun Kumar Mallik, Yuliya Semenova

Articles

This paper experimentally demonstrates a method for geometrical profiling of asymmetries in fabricated thin microfiber tapers with waist diameters ranging from ∼10 to ∼50µm with submicron accuracy. The method is based on the analysis of whispering gallery mode resonances excited in cylindrical fiber resonators as a result of evanescent coupling of light propagating through the fiber taper. The submicron accuracy of the proposed method has been verified by SEM studies. The method can be applied as a quality control tool in fabrication of microfiber based devices and sensors or for fine-tuning of microfiber fabrication set-ups.

Secrecy And Randomness: Encoding Cloud Data Locally Using A One-Time Pad, Paul Tobin, Lee Edward Tobin, Mick Mckeever, Jonathan Blackledge

Articles

There is no secrecy without randomness, and we address poor cloud security using an analogue chaotic onetime pad encryption system to achieve perfect secrecy. Local encoding returns control to the client and makes stored cloud data unreadable to an adversary. Most cloud service providers encode client data using public encryption algorithms, but ultimately businesses and organisations are responsible for encoding data locally before uploading to the Cloud. As recommended by the Cloud Security Alliance, companies employing authentication and local encryption will reduce or eliminate, EU fines for late data breach discoveries when the EU implements the new general data protection …

Institutional Loyalties In Constitutional Law, Aziz Huq, David Fontana

Articles

No abstract provided.

Investigation Of Temperature Response Of Photopolymer Material Used For Holographic Sensor, Muhammad Irfan Dr, Tatsiana Mikulchyk Dr, Suzanne Martin Dr, Izabela Naydenova Prof

Articles

Recently, functionalised photopolymer has emerged as a versatile recording material in the field of optical holography due to its novel characteristics and potential use in the development of holographic based sensors, and optical elements. This work describes the temperature response of a newly developed photopolymer, containing of a monomer Nisopropylacrylamide (NIPA) which under photopolymerisation forms a temperature sensitive polymer - Poly(Nisopropylacrylamide) (PNIPA). The photonic sensor was developed by holographic recording of volume phase transmission gratings in a self-processing NIPA-based polymer with a 532 nm laser beam. A 633 nm probe beam was used to monitor real time diffraction efficiency (DE) …

A High-Temperature Humidity Sensor Based On A Singlemode-Side Polished Multimode-Singlemode Fiber Structure, Xianfan Wang, Ke Tian, Libo Yuan, Elfed Lewis, Gerald Farrell, Pengfei Wang

Articles

A relative humidity (RH) sensor based on a simple singlemode-side polished multimode-singlemode (SSPMS) fiber hybrid structure is investigated, which is capable of working over a relatively high-temperature range, at which many RH sensors based on moisture sensitive material coatings cannot operate. The beam propagation method is used to analyze the light transmission characteristics within the side polished multimode fiber (SPMMF) structure. Experimental results show that the SPMMF surface roughness has a significant influence on the sensor's humidity sensing performance, as a result of the adsorption and desorption of water molecules along the side polished surface. A higher surface roughness results …

Thermal Modeling And Experimental Evaluation Of Five Different Photovoltaic Modules Integrated On Prototype Test Cells With And Without Water Flow, Vivek Tomar, G.N. Tiwari, T.S. Bhatti, Brian Norton

Articles

An analytical model of temperature dependent electrical and thermal efficiency of mono-crystalline (m-Si), polycrystalline (p-Si), amorphous silicon thin film (a-Si), cadmium telluride thin film (CdTe) and copper indium gallium selenide (CIGS) photovoltaic modules integrated on five prototypes identical insulted test cells is developed with and without surface water flow. This model helps in ascertaining the influence of temperature on their performance of building integrated photovoltaic-thermal (BiPVT) system. The theoretically calculated results are experimentally validated in outdoor ambient environment. The electrical & thermal efficiencies are calculated for both high and low mass flow rate of water, ṁw. Daily average electrical efficiency …

Muddy Waters: Refining The Way Forward For The “Sustainability Science” Of Socio-Hydrogeology, Paul Hynds, Shane Regan, Luisa Andrade, Simon Mooney, Kevin O'Malley, Stephanie Dipelino, Jean O'Dwyer

Articles

The trouble with groundwater is that despite its critical importance to global water supplies, it frequently attracts insufficient management attention relative to more visible surface water sources, irrespective of regional climate, socioeconomic profile, and regulatory environment. To this end, the recently defined sub-discipline of "socio-hydrogeology", an extension of socio-hydrology, seeks to translate and exchange knowledge with and between non-expert end-users, in addition to involving non-expert opinion and experience in hydrogeological investigations, thus emphasising a "bottom-up" methodology. It is widely acknowledged that issues pertaining to groundwater quality, groundwater quantity, climate change, and a poor general awareness and understanding of groundwater occurrence …

K-Means And Hierarchical Cluster Analysis As Segmentation Algorithms Of Ftir Hyperspectral Images Collected From Cutaneous Tissue, Cassio Lima, Luciana Correa, Hugh Byrne, Denise Zezell

Articles

Fourier Transform Infrared (FTIR) spectroscopy is a rapid and label-free analytical technique whose potential as a diagnostic tool has been well demonstrated. The combination of spectroscopy and microscopy technologies enable wide-field scanning of a sample, providing a hyperspectral image with tens of thousands of spectra in a few minutes. In order to increase the information content of FTIR images, different clustering algorithms have been proposed as segmentation methods. However, systematic comparative tests of these techniques are still missing. Thus, the present paper aims to compare the ability of K-means Cluster Analysis (KMCA) and Hierarchical Cluster Analysis (HCA) as clustering algorithms …

Non-Crossing Partitions And Milnor Fibers, Colum Watt, Michael Falk, Thomas Brady

Articles

For a finite real reflection group, W, we use non-crossing partitions of type W to construct a finite cell complex with the homotopy type of the Milnor fiber of the associated W–discriminant, Δ_W, and another with the homotopy type of the Milnor fiber of the defining polynomial of the associated reflection arrangement. These complexes support natural cyclic group actions realizing the geometric monodromy. Using the shellability of the non-crossing partition lattice, this cell complex yields a chain complex of homology groups computing the integral homology of the Milnor fiber of Δ_W.

General Dissipative Materials For Simple Histories, John Murrough Golden, G. Amendola, M. Fabrizio

Articles

A material with memory typically has a set of many free energy functionals associated with it, all members of which yield the same constitutive relations. An alternative interpretation of this set is explored in the present work. Explicit formulae are derived for the free energy and total dissipation of an arbitrary material in the cases of step function and sinusoidal/exponential histories. Expressions for the fraction of stored and dissipated energy are deduced. Also, various formulae are given for discrete spectrum materials. For materials with relaxation function containing one decaying exponential, the associated Day functional is the physical free energy. For …

Discriminants Of Polynomials In The Archimedean And Non-Archimedean Metrics, Vasili Bernick, Natalia Budarina, Hugh O'Donnell

Articles

An upper bound for the number of cubic polynomials which have small discriminant in terms of the Euclidean and p-adic metrics simultaneously is obtained.

A Conceptual Framework For Understanding The Biogeochemistry Of Dry Riverbeds Through The Lens Of Soil Science, Maria Isabel Arce, Clara Mendoza, Maria Almagro, Nuria Catalan, Anna M. Romani, Eugenia Marti, R. Gomez, Susana Bernal, Arnaud Foulquier, Michael Mutz, Rafael Marce, Annamaria Zoppini, Giulia Gionchetta, Gabriele Weigelhofer, R. Del Campo, Christopher T. Robinson, Alan Gilmer, Martin Rulik, Obrador Biel, Oleksandra Shumilova, Sanja Zlatanovic, Shai Arnon, Petr Baldrian, Gabriel Andreas Singer, Thibault Datry, Nikolaos Th Skoulikidis, Britta Tietjen, Daniel Von Schiller

Articles

Intermittent rivers and ephemeral streams (IRES) encompass fluvial ecosystems that eventually stop flowing and run dry at some point in space and time. During the dry phase, channels of IRES consist mainly of dry riverbeds (DRBs), prevalent yet widely unexplored ecotones between dry and wet phases that can strongly influence the biogeochemistry of fluvial networks. DRBs are often overlooked because they do not strictly belong to either domain of soil or freshwater science. Due to this dual character of DRBs, we suggest that concepts and knowledge from soil science can be used to expand the understanding of IRES biogeochemistry. Based …

High Sensitivity Temperature Sensor Based On Singlemode-No-Core- Singlemode Fibre Structure And Alcohol, Ke Tiana, Gerald Farrell, Xianfan Wang, Yifan Xin, Yanqiu Du, Wenlei Yang, Haidong Liang, Elfed Lewis, Pengfei Wang

Articles

A high sensitivity temperature sensor based on a singlemode-no-core-singlemode (SNCS) fibre structure and surrounded with alcohol within a silica capillary is described. In this investigation, no-core fibre (NCF) is used as the multimode waveguide and alcohol is chosen as the temperature sensitive medium. By packaging the alcohol solution with a short length of NCF enclosed within a silica capillary, the surrounding temperature can be detected by monitoring the variations of transmission loss at a specific wavelength. The theoretical analysis predicts this temperature sensor can provide high sensitivity, and the experimental results support this. The maximum temperature sensitivity of the sample …

Introducing A New Cement Hydration And Microstructure Model, Niall Holmes

Articles

This paper presents a new cement hydration model (HYDCEM) to predict the microstructure evolution of hydrating tricalcium silicate (C3S). The model is written in MATLAB and employs the continuum approach and integrated particle kinetics relationships to show the change in C3S and the growth of Calcium Silicate Hydrate (C-S-H) and Calcium Hydroxide (CH) in the pore space over time. Cement hydration is a highly complex process. While hydration models should never completely remove experimental analysis, they are an aid to better understand cement hydration and microstructure development by providing a method to analyse a large number of pastes with different …

Nano–Bio Interactions: Nanomedicine And Nanotoxicology, Hugh Byrne, S. Mukherjee, Pratap C. Naha

Articles

The 21st century has truly become the age of nanotechnology. Nanomaterials, design strategies, and processing have already made a significant impact in areas of materials science and electronics, with many commercial applications already being available on the consumer market. However, the ability to manipulate material functions and interactions on a scale of tens of nanometers, e.g., biological subcellular organelles, may yet prove to have the most significant impact on human health and the environment.