Digital Commons Network^™

Impaired Clearance And Enhanced Pulmonary Inflammatory/Fibrotic Response To Carbon Nanotubes In Myeloperoxidase-Deficient Mice, Aidan Meade, Anna Shvedova, Alexandr Kapralov, Wei Hong Feng, Elena Kisin, Ashley Murray, Robert Mercer, Claudette St. Croix, Megan Lang, Simon Watkins, Nagarjun Konduru, Brett Allen, Jennifer Conroy, Gregg Kotchey, Bashir Mohamed, Yuri Volkov, Alexander Star, Bengt Fadeel, Valerian Kagan

Articles

Advancement of biomedical applications of carbonaceous nanomaterials is hampered by their biopersistence and proinflammatory action in vivo. Here, we used myeloperoxidase knockout B6.129X1-MPO (MPO k/o) mice and showed that oxidation and clearance of single walled carbon nanotubes (SWCNT) from the lungs of these animals after pharyngeal aspiration was markedly less effective whereas the inflammatory response was more robust than in wild-type C57Bl/6 mice. Our results provide direct evidence for the participation of MPO – one of the key-orchestrators of inflammatory response – in the in vivo pulmonary oxidative biodegradation of SWCNT and suggest new ways to control the biopersistence of …

An Investigation In The Development Of Europe's Erasmus Internship Policy, Frank Cullen

Articles

The involvement of the School of Culinary Arts and Food Technology in international mobility for work placement has experienced exponential growth over the past five years with the assistance of European Leonardo da Vinci and Erasmus funding for European internships. The main purpose behind the European Commission funding ventures for internship (experiential learning) is to enhance the students’ cultural awareness, cultivate their language skills and develop their professionalism in their field of study. This paper provide an overview of the development of Erasmus internship and relationship between the the European Commission, the HEA, and DIT.

What Is The Pensee Sauvage And Is It Still Alive In Modern Society?, Mark William Farrell

Articles

The culinary process has changed somewhat down through the ages but not to any great extent. The raw materials are still similar but innovation and creativity has been applied to them to give the finished product varying degrees of taste, texture, sensory and aesthetic pleasure. Fundamentally the tools which we use to interpret or rate our food are the very same apparatus which animals use to define theirs. The anthropology of sensory perception is essentially the same for animals and man in an evolutionary perspective (Pasquet, Simmen & Pagezy, 2000). It reflects the capacity of the animal or primitive human …

The Positive Role Of Breastfeeding On Infant Health During The First 6 Weeks: Findings From A Prospective Observational Study Based On Maternal Reports, Roslyn Tarrant, Margaret Sheridan-Pereira, Katherine Younger, John Kearney

Articles

This study aimed to report on adverse infant and maternal clinical outcomes, and investigate the relationship between infant feedingpractice and such adverse clinical outcomes in infants during the first 6 weeks postpartum. From an eligible sample of 450 motherterminfant pairs recruited from the Coombe Women and Infants University Hospital in Dublin, 27.1% of infants (n=122) werematernally reported to have had an illness during the first 6 weeks that necessitated the provision of prescribed medication ± generalpractitioner/paediatrician attendance ± hospitalisation. Of these, 90 infants had ≥1 episode of infection ± viral ± gastro-intestinalrelatedcondition. After adjustment, ‘any’ breastfeeding to 6 weeks was …

Disciplinary Identity Of Nanoscience And Nanotechnology Research- A Study Of Postgraduate Researchers’ Experiences, Deepa Nathamuni Chari, Robert Howard, Brian Bowe

Articles

Nanoscience and Nanotechnology research although growing at very fast rate, its disciplinary identity remains ‘ill-defined’. It is often viewed as multidisciplinary; and/or interdisciplinary science or even as a unique discipline on its own way. As a consequence, whether this growing research area requires researchers that have studied specialised undergraduate or postgraduate nanoscience and nanotechnology programmes; or traditional science and engineering disciplines is still less understood. The examination of postgraduate researchers’ experiences of nanoscience and nanotechnology research can provide a way of understanding nanoscience and nanotechnology research and the associated forms of disciplinarity, which in turn can address what the type …

Physicochemical And Microbiological Quality Of Harvested Rainwater From An Agricultural Installation In Ireland, Sean O'Hogain, Liam Mccarton, Niamh Mcintyre, Jenny Pender, Anna Reid

Articles

Members of DTC Research Group. Dublin Institute of Technology was commissioned in 2005 by the Department of Environment, Heritage and Local Government in Ireland to assess the feasibility of utilising rainwater to replace treated mains water for nonpotable uses. The project involved the design, installation, commissioning and monitoring of rainwater harvesting on a farm. Two monitoring programmes, Regime 1 and Regime 2, examined the physicochemical and microbiological quality of the harvested rainwater. Samples were taken monthly and tested. Regime 1 analysis showed that the microbiological quality of the rainwater from the site did not comply with the requirements of the …

Refraction And Prescribing, Claire E. Mcdonnell

Articles

Refraction and prescribing are two different concepts and often a prescribed correction is not the same as the error found in the testing room. This article explores the reasons why the results of a refraction may not necessarily be identical to the correction the patient needs to wear.

Preparation And Rapid Analysis Of Antibacterial Silver, Copper And Zinc Doped Sol–Gel Surfaces, Swarna Jaiswal, Brendan Duffy, Patrick Mchale

Articles

The colonisation of clinical and industrial surfaces with microorganisms, including antibiotic-resistant strains, has promoted increased research into the development of effective antibacterial and antifouling coatings. This study describes the preparation of metal nitrate (Ag, Cu, Zn) doped methyltriethoxysilane (MTEOS) coatings and the rapid assessment of their antibacterial activity using polyproylene microtitre plates. Microtitre plate wells were coated with different volumes of liquid sol–gel and cured under various conditions. Curing parameters were analysed by thermogravimetric analysis (TGA) and visual examination. The optimum curing conditions were determined to be 50–70 °C using a volume of 200 μl. The coated wells were challenged …

Review Of Ultrasound Elastography Quality Control And Training Test Phantoms, S. Cournane, Andrew Fagan, Jacinta Browne

Articles

While the rapid development of ultrasound elastography techniques in recent decades has sparked its prompt implementation in the clinical setting adding new diagnostic information to conventional imaging techniques, questions still remain as to its full potential and efficacy in the hospital environment. A limited number of technical studies have objectively assessed the full capabilities of the different elastography approaches, perhaps due, in part, to the scarcity of suitable tissue-mimicking materials and appropriately designed phantoms available. Few commercially-available elastography phantoms possess the necessary test target characteristics or mechanical properties observed clinically, or indeed reflect the lesion-to-background elasticity ratio encountered during clinical …

Evaluation And Identification Of Markers Of Damage In Mushrooms (Agaricus Bisporous) Postharvest Using A Gc/Ms Metabolic Profiling Approach., Aoife O'Gorman, Catherine Barry-Ryan, Jesus Maria Frias

Articles

The aim of this research was to use the gas mass spectrometry (GC/MS) profiling method coupled with chemometric tools to profile mechanically damaged and undamaged mushrooms during storage and to identify specific metabolites that may be used as markers of damage. Mushrooms grown under controlled conditions were bruise damaged by vibration to simulate damage during normal transportation. Three damage levels were evaluated; undamaged, damaged for 20 min and damaged for 40 min and two time levels studied; day zero and day one after storage at 48C. Applying this technique over 100 metabolites were identified, quantified and compiled in a library. …

Assessment Of An Osteoblast-Like Cell Line As A Model For Human Primary Osteoblasts Using Raman Spectroscopy, Lindsay Mcmanus, Franck Bonnier, George Burke, Brian Meenan, Adrian Boyd, Hugh Byrne

Articles

Raman spectroscopy is employed to determine the suitability of the U20S osteoblast-like cell line for use as a model for human primary osteoblasts, with emphasis on the ability of these cell types to replicate their tissue of origin. It was found that both cell types demonstrated early stage mineral deposition that followed significantly different growth patterns. Analysis of the growth pattern and spectral data from primary cells revealed increasing bone quality ratios and a high crystallinity, consistent with previous reports. Conversely the investigation of the U20S osteoblast-like cell line provided evidence of dense multilayered mineralised regions that corresponded more closely …

Genetic Analysis Of Relative Water Content (Rwc) In Two Recombinant Inbred Line Populations Of Soybean [Glycine Max (L.) Merr.], Salvador Virginia, Megan Pagan, Melissa Cooper, Stella K. Kantartzi, David A. Lightfoot, Khalid Meksem, My Abdelmajid Kassem

Articles

Drought affects soybean [Glycine max (L.) Merr.] and other crops productivity in the US and other parts of the world. Relative water content (RWC) is an important indicator for plant water deficit tolerance (WDT). The objective of this study is to map quantitative trait loci (QTL) for RWC and several other leaf traits such as leaf dry weight (LDW), leaf fresh weight (LFW), and leaf turgid weight (LTW) in two soybean recombinant inbred line (RIL) populations, one derived from a cross of ‘Essex’ and ‘Forrest’ (ExF, n=94) and the other is derived from a cross of ‘PI 438489B’ and …

New Approaches To Selecting Resistance Or Tolerance To Sds And Fusarium Root Rot, Jiazheng Yuan, Rabia Bashir, Graciela Salas, Hemlata Sharma, Ali Srour, David A. Lightfoot

Articles

Fusarial rots are a significant problem worldwide affecting roots (and sometimes fruits) of most major crops including soybean, maize and wheat. Cultivar variation in partial resistance or tolerance is widespread and significant. Different cultivars of the soybean [Glycine max (L.) Merr.] have both resistance/tolerance to the leaf scorch known as Sudden Death Syndrome (SDS) and to the infection and root rot by the causal organism, Fusarium virguliforme (ex. F. solani f. sp glycines) hence the syndrome is composed of two diseases (1-3). Thirteen loci have been identified from analysis of 7 different crosses (2). Using new strains and new …

Using A Minimum Tile Path For Plant Transformations Encompassing The Entire Soybean Genome, Hidayat Ullah, Mohammed Jasim, David A. Lightfoot

Articles

Genomes like Glycine max (soybean) that have been highly conserved following increases in ploidy represent a frontier for genome analysis. Many soybean QTL analyzed to date have been composed of gene clusters each with contributing a portion of the trait rather than alleles of single genes. At the Soybean Genome Database (SoyGD) http://soybeangenome.siu.edu the genome browser that integrates and served the publicly available soybean physical map, BAC fingerprint database and genetic map associated genomic data shows a minimum tile of transformation ready BIBAC-like clones in pCLD04541 (pV41; oriV; tra; bom). Sequence resources made available through the DOE genome sequencing project …

Saving Their Own Souls: How Rluipa Failed To Deliver On Its Promises, Sarah Gerwig-Moore

Articles

In the summer of 2001, as a graduate student in law and theology, I began work on a master’s thesis that examined the predicament of men of faith on San Quentin’s Condemned Row. I was working in the California Appellate Project—mostly assisting with direct appeals and state habeas petitions on behalf of men under a death sentence—when a colleague guided me into theological conversations with some of our clients. On Condemned Row, they waited—up to five years to be assigned a court-appointed appellate attorney, on judges’ rulings, and to find whether the legal system would ultimately exact the penalty it …

Chevron, Greenwashing, And The Myth Of “Green Oil Companies”, Judd F. Sneirson

Articles

As green business practices grow in popularity, so does the temptation to “greenwash” one’s business to appear more environmentally and socially responsible than it actually is. We examined this phenomenon in an earlier paper, using BP and the Deepwater Horizon catastrophe as a case study and developing a framework for policing dubious claims of corporate social responsibility. This Article revisits these issues focusing on Chevron, an oil company that claims in its advertisements to care deeply about the environment and the communities in which it operates, even as it faces an $18 billion judgment for polluting the Ecuadorean Amazon and …

Exercise Is Medicine: Some Cautionary Remarks In Principle As Well As In Practice, Ross Neville

Articles

On the basis of extensive research on the relationship between physical activity, exercise and health, as well as strong support from policymakers and practitioners, the “Exercise is Medicine” initiative has become something of a linchpin in the agenda for modern healthcare reform and reflects a broader acceptance that the philosophy of health politics must shift from social engineering to performativity. However, in spite of the avowed commitment to encouraging individuals to take on a more reflexive relation to their health, it remains unclear as to whether an initiative such as this is, unambiguously, a good thing. In this paper, a …

Considering A Complemental Model Of Health And Fitness, Ross Neville

Articles

This article examines the concept of fitness, which, in spite of its much avowed cultural significance, has become the subject of much critical attention. In particular, it considers the now contested relation of fitness to health; the fact that, although there appears to be a clear consensus on a simple causal relation between the two, this has been deemed illusory outside the medico-scientific context of its production. In response to the problems with both of these positions, this article examines the potential for reconfiguring the relation between fitness and health on new terms. A complemental model of health and fitness …

Information-Seeking Behaviour Of Nurses: Where Is Information Sought And What Processes Are Followed?, Denise O'Leary, Siobhan Ni Mhaolrunaigh

Articles

Aim This paper is a report of a study on how nurses inform their decision-making in the workplace

Background Despite the growing availability of research evidence, nurses have been slow to adopt it into their daily decision-making.

Method The study was undertaken in Ireland between 2006 and 2007 using a sequential mixed methods approach. In phase 1, the views of a quota sample of 29 nurses were explored using semi-structured interviews incorporating vignettes. Phase 2 involved the design and dissemination of a survey to a disproportionate stratified random sample of 1356 nurses. The response rate was 29%.

Findings In decision-making, …

Hemp Lime Bio-Composite As A Building Material In Irish Construction, Patrick Daly, Paolo Ronchetti, Tom Woolley Dr

Articles

This report presents the findings of scoping study into the potential application of hemp lime biocomposite as a construction material in Irish context. The research was carried out under STRIVE funding administered under the Irish Environmental Protection Agency (EPA) examining the state of play of hemp lime in construction toward assessing its potential application in Ireland.

The research involved a range of methods, mainly qualitative, including significant literature review and extensive collation of data on hemp lime performance and testing data, semi structured interviews and field work / review of key case studies in Ireland, UK and Europe.

The study …

Too Rough A Justice: The Ethiopia-Eritrea Claims Commission And Civil Liability For Claims For Rape Under International Law, Ryan S. Lincoln

Articles

The developments in international law prohibiting rape during armed conflict have grown at a rapid pace in recent decades. Whereas rape had long been considered an inevitable by-product of armed conflict, evolution in international humanitarian law (IHL) has relegated this conception mostly to the past. The work of international criminal tribunals has been at the forefront of this change, developing the specific elements of the international crime of rape, and helping to change the perception of rape in international law violations of IHL, however also give rise to civil liability Despite the advances with respect to rape made in the …

Must-Have Books: Critical Reading For Your Classroom Library, Jane Leeth

Articles

Visiting Scholar Katherine Bomer shared more than four dozen books with teachers at our 2012 Winter Workshop, helping us envision Critical Reading and Writing for Social Action units for our own classrooms. If you missed the workshop or didn’t get to see all of Katherine’s 50+ books, IPYW reading workshop coach Jane Leeth can help. Here, Jane presents her “must-have” recommendations from Katherine’s stack—including grade levels and story descriptions.

The Irony Of Hosanna-Tabor Evangelical Lutheran Church And School V Eeoc, Caroline Mala Corbin

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In Hosanna-Tabor Evangelical Lutheran Church and School v. EEOC, a schoolteacher sued her employer for retaliating against her in violation of the American with Disabilities Act (ADA). The success of her ADA claim turned on whether the Supreme Court thought that she was a minister. If she was not a minister, she would have probably won. After all, the school stated in writing that a main reason for her termination was her threatened lawsuit. But because the Supreme Court decided that she was a minister, and that ministers may not sue their religious employers for discrimination under the ministerial …

Effect Of Drip Irrigation Circuits Design And Lateral Line Length On: Ii-Flow Velocity And Velocity Head, Mohamed Yousif Tayel, David A. Lightfoot, Hani A.-G. Mansour

Articles

The objectives of the work were to study the effect of drip irrigation circuits (DIC) and lateral lines lengths (LLL) on: Flow velocity (FV) and velocity head (VH). Laboratory tests were con- ducted at Irrigation Devices and Equipments Tests Laboratory, Agricultural Engineering Research Institute, Agriculture Research Center, Giza, Egypt. The experimental design of laboratory experiments was split in randomized complete block design with three replicates. Laboratory tests carried out on three irrigation lateral lines 40, 60, 80 m (LLL₁, LLL₂; LLL₃) under the following three drip irrigation circuits (DIC): a) one manifold for lateral …

Reducing Recidivism Through Entrepreneurship Programmes In Prisons, Thomas Cooney

Articles

Prison systems are facing significant challenges from overcrowding and a ‘revolving door’ routine. Reducing recidivism would help alleviate both these problems and would also assist in breaking the cycle of career criminality. However, one of the primary causes of recidivism is a lack of employment opportunities for people who have spent time in prison, thereby causing them to return to crime. Given the dearth of entrepreneurship research on ex-prisoners, this paper examines a ‘Start Your Own Business’ programme delivered inside a prison. Based on interviews with the participants, the author examines whether such programmes offer a realistic opportunity for reducing …

Connectedness In The Lives Of Older People In Ireland, Carmel Gallagher

Articles

This paper presents an analysis of the connectedness of older people in two sample areas, one urban and one rural in Ireland. The paper is based on a study of the communal participation of older people in two geographic localities, Rathmore, a suburban area of Dublin, and Rathbeg, a rural area in County Donegal, conducted between 2000 and 2005. A multi stage study that used both qualitative and quantitative methods examined significant communal interactions of older people across a range of arenas, including leisure interests, involvement in clubs, religious practices, voluntary work, relationships with kin, friends and neighbours, helping activities, …

The Impact Of The Rise And Fall Of Chevron On The Executive's Power To Make And Interpret Law, Linda Jellum

Articles

The Supreme Court's willingness to defer to agency interpretations of ambiguous statutes has vacillated over the past seventy years. The Court's vacillation has dramatically impacted the executive 's power to make and interpret law. This Article examines how the Court augmented then constricted executive lawmaking power and ceded then reclaimed executive interpretive power with a single case and its legal progeny. Chevron U.S.A., Inc. v. Natural Resources Defense Council, Inc. and its aftermath dramatically altered the executive's power to make and interpret law. Prior to Chevron, Congress had the primary responsibility for lawmaking, while agencies made policy choices primarily when …

Resilience And Water Governance: Adaptive Governance In The Columbia River Basin, Barbara Cosens

Articles

The 1964 Columbia River Treaty between the United States and Canada is currently under review. Under the treaty, the river is jointly operated by the two countries for hydropower and is the largest producer of hydropower in the western hemisphere. In considering the next phase of international river governance, the degree of uncertainty surrounding the drivers of change complicates efforts to predict and manage under traditional approaches that rely on historical ecosystem responses. At the same time, changes in social values have focused attention on ecosystem health, the decline of which has led to the listing of seven salmon and …

Dealing With Overcrowding In Prisons: Contrasting Judicial Approaches From The Usa And Ireland., Mary Rogan

Articles

Two recent decisions, one given by the Supreme Court of the United States of America and one of the Irish High Court, address the consequences of overcrowding in prisons. In Brown, Governor of California et at v. Plata et al1 (hereinafter Plata) the US Supreme Court upheld a decision of a three judge federal court requiring the State of California to reduce its prison population to 137.5% of the prison system’s design capacity, requiring the release of up to 46,000 prisoners. The Court agreed that the overcrowding in the Californian prison system had caused the breach of prisoners’ rights under …

Improving Criminal Justice Data And Policy, Mary Rogan

Articles

Criminal justice policy in Ireland is often criticised for lacking a robust evidence base.

Increased knowledge about crime and criminal justice may act to enrich all types of criminological enquiry and policy formation. This paper explores the potential of large population registries, similar to those created in the health sector, to inform criminal justice policymaking. The paper looks at the importance of such data collection for criminal justice research and policy and the potential hurdles to its development.