Digital Commons Network^™

A Nanoscale Shape-Discovery Framework Supporting Systematic Investigations Of Shape-Dependent Biological Effects And Immunomodulation, Wei Zhang, Hender Lopez, Luca Boselli, Paolo Bigini, André Perez-Potti, Zengchun Xie, Valentina Castagnola, Qi Cai, Camila P. Silveira, Joao M. De Araujo, Laura Talamini, Nicolò Panini, Giuseppe Ristagno, Martina B. Violatto, Stéphanie Devineau, Marco P. Monopoli, Mario Salmona, Valeria A. Giannone, Sandra Lara, Kenneth A. Dawson, Yan Yan

Articles

Since it is now possible to make, in a controlled fashion, an almost unlimited variety of nanostructure shapes, it is of increasing interest to understand the forms of biological control that nanoscale shape allows. However, a priori rational investigation of such a vast universe of shapes appears to present intractable fundamental and practical challenges. This has limited the useful systematic investigation of their biological interactions and the development of innovative nanoscale shape-dependent therapies. Here, we introduce a concept of biologically relevant inductive nanoscale shape discovery and evaluation that is ideally suited to, and will ultimately become, a vehicle for machine …

Artificial Intelligence-Based Power System Stabilizers For Frequency Stability Enhancement In Multi-Machine Power Systems, Aliyu Sabo, Noor Izzri Abdul Wahab, Mohammad Lutfi Othman, Mai Zurwatul Ahlam Mohd Jaffar, Hakan Acikgoz, Hamed Nafisi, Hossein Shahinzadeh

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Low frequency oscillations (LFOs) occur in a system of interconnected generators connected by weak interconnection. A power system stabilizer (PSS) is commonly used to improve the capacity of the power system dampening. Under a variety of operating conditions, traditional PSSs fail to deliver superior damping. To address this issue, a Farmland Fertility Algorithm (FFA-PSSs controller) was used to solve an optimization problem for optimal design of PSSs system parameters, and its performance efficiency was compared to GA and PSO-based PSSs controllers. In addition to PSS, flexible current transmission (FACTS) devices are widely used. PSSs controllers and FACTS devices are frequently …

A Sinusoidal Signal Reconstruction Method For The Inversion Of The Mel-Spectrogram, Anastasia Natsiou, Sean O'Leary

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The synthesis of sound via deep learning methods has recently received much attention. Some problems for deep learning approaches to sound synthesis relate to the amount of data needed to specify an audio signal and the necessity of preserving both the long and short time coherence of the synthesised signal. Visual time-frequency representations such as the log-mel-spectrogram have gained in popularity. The log- mel-spectrogram is a perceptually informed representation of audio that greatly compresses the amount of information required for the description of the sound. However, because of this compression, this representation is not directly invertible. Both signal processing and …

Workplace Dispute Resolution In Ireland At A Crossroads: Challenges And Opportunities, Brian M. Barry Dr

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The Workplace Relations Act 2015 fundamentally reformed the workplace dispute resolution system in Ireland–the centrepiece being the Workplace Relations Commission, the new body for first-instance dispute resolution. While the overall system is an improvement on its overly-complex and confusing predecessor, the Supreme Court’s decision in Zalewski v An Adjudication Officer declaring aspects of adjudication at the WRC unconstitutional, coupled with user representatives’ persistent concerns about how adjudication is conducted, present ongoing challenges.

This article describes the results of a survey undertaken in 2019 by the author of over one hundred representatives’ views on the system, and contextualises them in light …

Corticothalamic Projections Deliver Enhanced Responses To Medial Geniculate Body As A Function Of The Temporal Reliability Of The Stimulus, Srinivasa P Kommajosyula, Edward L Bartlett, Rui Cai, Lynne Ling, Donald M Caspary

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Ageing and challenging signal-in-noise conditions are known to engage the use of cortical resources to help maintain speech understanding. Extensive corticothalamic projections are thought to provide attentional, mnemonic and cognitive-related inputs in support of sensory inferior colliculus (IC) inputs to the medial geniculate body (MGB). Here we show that a decrease in modulation depth, a temporally less distinct periodic acoustic signal, leads to a jittered ascending temporal code, changing MGB unit responses from adapting responses to responses showing repetition enhancement, posited to aid identification of important communication and environmental sounds. Young-adult male Fischer Brown Norway rats, injected with the inhibitory …

Social Media Influencers (Smis) In Context: A Literature Review, Charles Alves De Castro, Isobel O'Reilly Dr, Aiden Carthy

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This review focused on three main areas, "Social Media Influencers (SMIs) in Context, The Impact of SMIs on Adolescents, and Consumer Behaviour in a Digital Era – Generation Z in Perspective". This article aims to further the overall understanding of SMIs and outlines the impact of SMIs on adolescents‘ lives. Thus, the main objective of this literature review is to raise awareness within the marketing field about the influence of social media influencers on adolescents and how brands promote their products and content through social media influencers. The review comprised a regular search using electronic journal databases and secondary data …

Notions Of Explainability And Evaluation Approaches For Explainable Artificial Intelligence, Giulia Vilone, Luca Longo

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Explainable Artificial Intelligence (XAI) has experienced a significant growth over the last few years. This is due to the widespread application of machine learning, particularly deep learning, that has led to the development of highly accurate models that lack explainability and interpretability. A plethora of methods to tackle this problem have been proposed, developed and tested, coupled with several studies attempting to define the concept of explainability and its evaluation. This systematic review contributes to the body of knowledge by clustering all the scientific studies via a hierarchical system that classifies theories and notions related to the concept of explainability …

Audio Representations For Deep Learning In Sound Synthesis: A Review, Anastasia Natsiou, Sean O'Leary

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The rise of deep learning algorithms has led many researchers to withdraw from using classic signal processing methods for sound generation. Deep learning models have achieved expressive voice synthesis, realistic sound textures, and musical notes from virtual instruments. However, the most suitable deep learning architecture is still under investigation. The choice of architecture is tightly coupled to the audio representations. A sound’s original waveform can be too dense and rich for deep learning models to deal with efficiently - and complexity increases training time and computational cost. Also, it does not represent sound in the manner in which it is …

Profiling Food Festivals By Type, Name And Descriptive Content: A Population Level Study, Muhammet Kesgin, Rajendran S. Murthy, Rick Lagiewski

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Purpose: This research aims to classify and describe food festivals and examine the patterns in food festival naming and festival descriptions in online media. Design: This research represents the first population-level empirical examination of food festivals in the United States using a purpose-built dataset (N=2626). Methodology includes text mining to examine food festival communications. Findings: Food festival size varies across local and regional spheres within the country. Food festivals employ geographical (place-, destination-based) associations in their names. Food festivals’ descriptions and online communications showcase a welcoming environment predominantly emphasizing family-oriented and live entertainment experiences. Food festivals across the country show …

Realising Compact Growth In Dublin; Reviewing Measures Adopted By Local Authorities To Concentrate Development Along The Proposed Metrolink Luas Greenline Transport Corridor, Paul J. Lawlor Mr

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Since 1999, there have been a noticeable evolution in the Irish national and regional planning policy towards concentrating new development within the footprint of existing towns and cities. The approach of ‘realising compact growth’ has numerous benefits including reducing carbon emissions, making more effective and economic use of existing infrastructure, avoiding urban sprawl and helping to achieve more balanced regional development. To enable its achievement, the National Planning Framework (NPF) and the Regional Spatial and Economic Strategies (RSESs) have set ambitious targets for compact urban growth and they include measures that are designed to promote the development of vacant and …

A Novel Parabolic Model Of Instructional Efficiency Grounded On Ideal Mental Workload And Performance, Luca Longo, Murali Rajendran

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Instructional efficiency within education is a measurable concept and models have been proposed to assess it. The main assumption behind these models is that efficiency is the capacity to achieve established goals at the minimal expense of resources. This article challenges this assumption by contributing to the body of Knowledge with a novel model that is grounded on ideal mental workload and performance, namely the parabolic model of instructional efficiency. A comparative empirical investigation has been constructed to demonstrate the potential of this model for instructional design evaluation. Evidence demonstrated that this model achieved a good concurrent validity with the …

A Survey Of Machine Learning Techniques For Video Quality Prediction From Quality Of Delivery Metrics, Obinna Izima, Ruairí De Fréin, Ali Malik

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A growing number of video streaming networks are incorporating machine learning (ML) applications. The growth of video streaming services places enormous pressure on network and video content providers who need to proactively maintain high levels of video quality. ML has been applied to predict the quality of video streams. Quality of delivery (QoD) measurements, which capture the end-to-end performances of network services, have been leveraged in video quality prediction. The drive for end-to-end encryption, for privacy and digital rights management, has brought about a lack of visibility for operators who desire insights from video quality metrics. In response, numerous solutions …

Beyond The Public Square: Imagining Digital Democracy, Mary Anne Franks

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To create online spaces that do not merely replicate existing hierarchies and reinforce unequal distributions of social, economic, cultural, and political power, we must move beyond the simplistic clich6 of the unregulated public square and commit to the hard work of designing for democracy.

When we say 'public square,' ... we need to ask- who or what is this public? Who owns this space, what makes it public? . . . This is the essence of democracy: the ability to question power, and the power to do so. - Tom Wilkinson

A Strategy Model For Workplace Mediation Success, Brian M. Barry Dr

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The article proposes a three-step model to help workplace mediators decide on the optimum strategy for mediating workplace disputes. The model uses a grid – the Workplace Mediation Strategy Grid – which is based on a modified version of a grid Professor Leonard Riskin developed for categorising mediation orientations (Riskin 1994; Riskin 1996). The model asks the mediator to first consider the nature of the workplace dispute based on three facets of the dispute. This guides the mediator to plot a position on the Grid which represents two fundamental aspects of strategy for mediating that dispute: (1) how broadly the …

Provenance: An Intermediary-Free Solution For Digital Content Verification, Bilal Yousuf, M. Atif Qureshi, Brendan Spillane, Gary Munnelly, Oisin Carroll, Matthew Runswick, Kirsty Park, Eileen Culloty, Owen Conlan, Jane Suiter

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The threat posed by misinformation and disinformation is one of the defining challenges of the 21st century. Provenance is designed to help combat this threat by warning users when the content they are looking at may be misinformation or disinformation. It is also designed to improve media literacy among its users and ultimately reduce susceptibility to the threat among vulnerable groups within society. The Provenance browser plugin checks the content that users see on the Internet and social media and provides warnings in their browser or social media feed. Unlike similar plugins, which require human experts to provide evaluations and …

Rces: Rapid Cues Exploratory Search Using Taxonomies For Covid-19, Wei Li, Rishi Choudhary, Arjumand Younus, Bruno Ohana, Nicole Baker, Brendan Leen, Muhammad Atif Qureshi

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To assist the COVID-19 focused researchers in life science and healthcare in understanding the pandemic, we present an exploratory information retrieval system called RCES. The system employs a previously developed EVE (Explainable Vector-based Embedding) model using DBpedia and an adopted model using MeSH taxonomies to exploit concept relations related to COVID-19. Various expansion methods are also developed, along with explanations and facets that collectively form rapid cues for a valuable navigational and informed user experience.

Love Hertz: Corporate Groups And Insolvency Forum Selection, John A. E. Pottow

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The Hertz bankruptcy got a lot of attention, including for its bizarre equity trading. A less heralded but more significant legal aspect of that insolvency, however, was its complex interaction of cross-border insolvency proceedings.

This article discusses the “centripetal” and “centrifugal” forces in the Hertz case that counselled a U.S.-based centralized solution for an international enterprise comprising over 10,000 branches centripetally but also accommodated centrifugal European resistance to subject directors to the consequences of filing their entities in a foreign jurisdiction. This not uncommon constellation of incentives required not a COMI shift but what this article terms a jurisdiction shift …

Editing And Interleaving, Patrick Barry

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This essay suggests that a powerful learning strategy called "interleaving"--which involves strategically switching between cognitive tasks--is being underused. It can do more than make study sessions more productive; it can also make editing sessions more productive.

Caring For The Souls Of Our Students: The Evolution Of A Community Economic Development Clinic During Turbulent Times, Gowri J. Krishna, Kelly Pfeifer, Dana Thompson

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Community Economic Development (CED) clinicians regularly address issues surrounding economic, racial, and social justice, as those are the core principles motivating their work to promote vibrant, diverse, and sustainable communities. When COVID-19 arrived, and heightened attention to police brutality and racial injustice ensued, CED clinicians focused not only on how to begin to address these issues in their clinics, but on how to discuss these issues more deeply and effectively with their students. This essay highlights the ways in which the pandemic school year influenced significant rethinking of one CED clinic’s operations: first, the pandemic sharpened the clinic’s mission to …

Towards An Integrated Case Method In Management Education - Developing An Ecosystem-Based Research And Learning Journey For Flipped Classrooms, Jan-Philipp Buechler Prof Dr, Gregor Brüggelambert Prof Dr, Jan-Phillip Büchler Prfo Dr, Helen De.Haan-Cao Dr, Asta Savaneviciene Prof

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In the field of management science and business administration, the case method is gaining ground in research as well as in teaching. Case studies support on the one hand exploratory re-search and on the other hand problem-based teaching. However, we find that case research and case teaching remain unchained in management study programs and propose to close this gap. We identify an untapped potential of boosting the case method by integrating case-based re-search and teaching into a discovery and learning journey of applied science. We suggest em-bedding the ‘Integrated Case Method’ (ICM) in the ecosystem of universities to the end …

Teaching Meiosis With The Dna Triangle Framework: A Classroom Activity That Changes How Students Think About Chromosomes, Leslie Kate Wright, Paulina Cortez, Margaret A. Franzen, Dina L. Newman

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Many biology students struggle to learn about the process of meiosis and have particular difficulty understanding the molecular basis of crossing over and the importance of homologous pairing for proper segregation. To help students overcome these challenges, we designed an activity that uses a newly developed Chromosome Connections Kit® from 3-D Molecular Designs to allow learners to explore meiosis at the molecular level. We took a backwards design approach in constructing an effective classroom activity. We developed evidence-based learning objectives and designed a crossing over activity that targets students' misconceptions and key concepts about meiosis. Assessment questions were designed based …

The Breakdown Of The Public-Private Divide In Securities Law: Causes, Consequences, And Reforms, George S. Georgiev

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As a regulatory scheme, U.S. securities law has traditionally been designed around a set of lines-the 'public-private divide"-which separate public companies, public capital, and public markets, from private companies, private capital, and private markets. Until the early 2000s, the lines were successful in establishing two largely coherent legal realms-a highly regulated public realm and a lightly regulated private realm. A series of bold and often-inconsistent reforms between 2002 and 2020, however, have transformed this longstanding regime into a low-friction system wherein public capital flows to both public and private companies, private capital is ever more abundant, and firms can effectively …

Special Matters: Filtering Privileged Materials In Federal Prosecutions, Christina Frohock

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This Article reviews the U.S. Department of Justice's toolbox for handling potentially privileged materials, with close attention to the evolution from filter teams to the Special Matters Unit in fraud prosecutions. Significant case opinions from the U.S. Courts of Appeals for the Fourth, Sixth, and Eleventh Circuits reveal the judiciary's diverse views on filter teams. The recent case of United States v. Esformes in the U.S. District Court for the Southern District of Florida, now on appeal to the Eleventh Circuit, illustrates how a filter team can fall short and draw unflattering attention to the Department of Justice. In the …

Funding Global Governance, Kristina B. Daugirdas

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Funding is an oft-overlooked but critically important determinant of what public institutions are able to accomplish. This article focuses on the growing role of earmarked voluntary contributions from member states in funding formal international organizations such as the United Nations and the World Health Organization. Heavy reliance on such funds can erode the multilateral governance of international organizations and poses particular risks for two kinds of undertakings: normative work, such as setting standards and identifying best practices; and evaluating the conduct of member states and holding those states accountable, including through public criticism, when they fall short. International organizations have …

Privacy As The Price Of Drug Access, Laura Karas

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In response to the recent increase in FDA-approved specialty drugs and escalating specialty drug prices, drug companies now offer patient support programs ("PSPs") for eligible patients prescribed a particular pharmaceutical drug. Such programs encompass both financial assistance for the purchase of a specialty drug and behavioral services, including nursing support and injection training, intended to improve drug adherence. Although ostensibly gratuitous, these programs have a steep and underappreciated cost: disclosure of protected health information. In effect, patient support programs compel patients to trade protected health information for drug access. This Article provides the first in-depth examination of the legal and …

Contract Schemas, Roseanna Sommers

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This review draws on the notion of “contract schemas” to characterize what ordinary people think is happening when they enter into contractual arrangements. It proposes that contracts are schematically represented as written documents filled with impenetrable text containing hidden strings, which are routinely signed without comprehension. This cognitive template, activated whenever people encounter objects with these characteristic features, confers certain default assumptions, associations, and expectancies. A review of the literature suggests that contract schemas supply (a) the assumption that terms will be enforced as written, (b) the feeling that one is obligated to perform, and (c) the sense that one …

Perspectives On Computing Ethics: A Multi-Stakeholder Analysis, Damian Gordon, Ioannis Stavrakakis, Paul J. Gibson, Brendan Tierney, Anna Becevel, Andrea Curley, Michael Collins, William O'Mahony, Dympna O'Sullivan

Articles

Purpose:

Computing ethics represents a long established, yet rapidly evolving, discipline that grows in complexity and scope on a near-daily basis. Therefore, to help understand some of that scope it is essential to incorporate a range of perspectives, from a range of stakeholders, on current and emerging ethical challenges associated with computer technology. This study aims to achieve this by using, a three-pronged, stakeholder analysis of Computer Science academics, ICT industry professionals, and citizen groups was undertaken to explore what they consider to be crucial computing ethics concerns. The overlap between these stakeholder groups are explored, as well as whether …

Punnett Square Or Protein Production? The Expert-Novice Divide For Conceptions Of Genes And Gene Expression, Dina L. Newman, Aeowynn Coakley, Aidan Link, Korinne Mills, Leslie Kate Wright

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Concepts of molecular biology and genetics are difficult for many biology undergraduate students to master yet are crucial for deep understanding of how life works. By asking students to draw their ideas, we attempted to uncover the mental models about genes and gene expression held by biology students (n = 23) and experts (n = 18) using semistructured interviews. A large divide was identified between novice and expert conceptions. While experts typically drew box-and-line representations and thought about genes as regions of DNA that were used to encode products, students typically drew whole chromosomes rather than focusing on gene structure …

Seaweed Polysaccharide In Food Contact Materials (Active Packaging, Intelligent Packaging, Edible Films, And Coatings), Kalpani Y. Perera, Shubham Sharma, Amit K. Jaiswal, Swarna Jaiswal

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Food contact materials (FCMs) are materials that come in contact with food products such as food packaging which play a significant role in the food quality and safety. Plastic, which is a major food packaging material, harms the eco-system, wildlife, and the environment. As a result, numerous researches have been in progress on alternative polymers, which has similar properties as plastic but is also environmentally friendly (biodegradable). In recent years, the utilization of seaweed polysaccharides has piqued interest due to its biodegradability, non-toxicity, antioxidant capabilities, and excellent film formation ability. However, it has a number of drawbacks such as low …

Ungrading, Supporting Our Students Through A Pedagogy Of Care, Shaun Ferns, Robert Hickey, Helen Williams

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The awarding of grades or marks to student work is traditionally considered a fundamental feature of assessment. Grades became more widely established in the twentieth century becoming ubiquitous across most educational institutions. There is increasing evidence to suggest that grades are not effective tools for promoting or measuring learning. One alternative approach for promoting and measuring learning is "Ungrading," in which no letter grades or marks are given to students. Instead, they are replaced with formative feedback provided through strategies such as individual feedback, peer review and self-assessment. An Ungrading approach promises increased learner motivation, a reduction in stress, and …