Digital Commons Network^™

Flight To Liquidity Or Safety? Recent Evidence From The Municipal Bond Market, Huixin Bi, Blake W. Marsh

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No abstract provided.

Efficacy Of Quikclot Combat Gauze When Used By Immediate Responders In A Simulated Gunshot Wound, Brenden Feingerts

Yale School of Medicine Physician Associate Program Theses

Gunshot wounds sustained by civilians in the context of active shooter events are distressingly common in the United States. Current guidelines recommend the use of advanced hemostatic dressings as the first-line treatment for gunshot wounds sustained to anatomical areas in which a tourniquet cannot be effectively deployed. These guidelines have been informed by studies conducted in military and surgical settings by trained medical personnel, however, no studies have been conducted to assess their efficacy when utilized by untrained civilian bystanders. In this study, we will compare the efficacy of QuikClot Combat Gauze to standard gauze for achieving hemostasis when utilized …

Efficacy Of Rimegepant Plus Calcitonin Gene-Related Peptide Monoclonal Antibody For Migraine, Carina Leggio

Yale School of Medicine Physician Associate Program Theses

Migraine is a paroxysmal pain disorder managed with abortive therapy during a pain attack, prophylactic therapy to prevent attacks, and often a combination of both. Calcitonin gene-related peptide (CGRP) and its receptor have a role in the provocation of migraines, and therefore have been targeted in the development of both preventive and abortive therapies. However, there is limited research investigating concomitant use of the therapies. This study will examine the safety and efficacy of oral rimegepant when used for acute treatment concomitantly with a monoclonal antibody (mAb) targeting the CGRP ligand or receptor for the preventive treatment of migraine. A …

Sudarshan Kriya Yoga And Alteration In Depression Severity And Default Mode Network Connectivity, Elizabeth Togneri

Yale School of Medicine Physician Associate Program Theses

Major depressive disorder is one of the most common and burdensome psychiatric disorders. Many individuals still experience symptoms despite pharmacological treatment. Breathing techniques have shown potential for stress, depression, and anxiety reduction. A second promising treatment are mindfulness-based interventions, which have been shown to effectively decrease depression with fewer side effects than pharmacological agents. Both interventions are accessible via remote instruction. This study will investigate the effect of Sudarshan Kriya Yoga breathwork on depression symptoms. Using a prospective, randomized controlled trial, subjects will receive Sudarshan Kriya Yoga, Mindfulness Based Stress Reduction, or standard care for 8-weeks. We will measure changes …

Coronary Angiogram Plus Invasive Physiologic Tests In Women With Nonobstructive Coronary Dysfunction, Megan Mccauley

Yale School of Medicine Physician Associate Program Theses

Ischemic heart disease is the leading cause of death for women in the Western hemisphere. Women with ischemic heart disease typically present to the emergency department with acute coronary syndrome, and subsequently undergo coronary angiography. In 66% of women, no evidence of obstructive disease is found, and current standard of care recommends no further diagnostic testing. However, nonobstructive diseases cannot be ruled out with coronary angiography alone and therefore are frequently missed. This study will examine whether invasive physiological testing with coronary angiography can impact multiple adverse cardiac events in adult women. Using a prospective comparative effectiveness trial, we will …

Behavioral And Emotional Changes Across Covid-19 School Experiences In Children And Adolescents, Brittney Gunneson

Yale School of Medicine Physician Associate Program Theses

The COVID 19 pandemic has necessitated several containment measures including full or partial remote learning for some children and adolescents. Displacement from school is known to be socially isolating with the potential to impact child behavior. However, the direction of effect of pandemic school closures on the emotional well-being of children and adolescents is not yet clear. This study aims to determine the effect of remote learning on emotional and behavioral changes in children and adolescents. Using participants from the Adolescent Brain Cognitive Development study, this longitudinal prospective cohort study will compare mean, current, and follow-up scores on the Child …

Sexual Function In Women Undergoing Risk Reducing Salpingo-Oophorectomy With Or Without Hysterectomy, Madeline Perez

Yale School of Medicine Physician Associate Program Theses

Bilateral Salpingo-Oophorectomies are offered to women with hereditary breast and ovarian cancer syndromes as prophylaxis to reduce the incidence of ovarian cancer. These surgeries induce acute surgical menopause and often result in compromised sexual function including decreased desire, sexual discomfort, and diminished sexual satisfaction. However, little is known about the differences in sexual function in women who undergo surgery with hysterectomy versus those that leave their uterus intact. Using a prospective cohort study, we will compare the effects of Bilateral Salpingo-Oophorectomy alone versus Bilateral Salpingo-Oophorectomy plus hysterectomy on sexual function in premenopausal women with breast cancer gene mutations. We will …

The Effect Of Plasma Levels Of Matrix Metalloproteinase-9 On Intracranial Aneurysm Progression, Peter Stampfel

Yale School of Medicine Physician Associate Program Theses

Intracranial aneurysms are a common vascular abnormality identified incidentally or after rupture leading to aneurysmal subarachnoid hemorrhage. However, accurately assessing the risk of aneurysmal disease progression is challenging. Here we propose a prospective cohort study to identify if elevated levels of matrix metalloproteinase-9, a molecular marker of vascular degeneration, in the peripheral blood samples of subjects with unruptured intracranial aneurysms correlate with aneurysm progression over a follow up period. This study aims to aid in identifying patients at increased risk of aneurysm progression in order to guide treatment decisions and ultimately decrease subarachnoid hemorrhage morbidity and mortality.

Spiritual Direction Practice In Physician Associates, Nicholas Nielsen

Yale School of Medicine Physician Associate Program Theses

Burnout affects nearly 50% of healthcare providers including physician associates throughout their professions. The extent of burnout experienced is directly related to the life satisfaction of these providers and to the level of care they provide their patients. One effective way to combat burnout is emotional intelligence practice, but there is little evidence to suggest that incorporating spiritual well-being can reduce burnout and improve life satisfaction in clinicians. In this study, we will assess the effect of spiritual guided practice on burnout and life satisfaction in physician associates. Using a non-blinded randomized control trial, we will select inpatient hospitalist physician …

Early Use Of Vaginal Progesterone And Cervical Pessary To Reduce Preterm Birth Rates In Twins, Thomas Vulaj

Yale School of Medicine Physician Associate Program Theses

Preterm birth is one of the most common causes of neonatal morbidity and mortality. The incidence of preterm birth can be reduced by treatment with vaginal progesterone or cervical pessary. However, no studies have supported a treatment regimen that can reduce preterm birth in twin pregnancies. In this study, we will examine whether a combination therapy of vaginal progesterone and cervical pessary can reduce preterm birth in women with dichorionic-diamniotic twin gestations. We will enroll pregnant women with dichorionic-diamniotic twins at 11-14 weeks’ gestation from a local hospital in a randomized control trial. This novel approach may help establish a …

Annual Report & Accounts For The 12 Months To 31 March 2021, Uk Asset Resolution

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No abstract provided.

Clone Of Re: Ela Administration, Spiros Pantelias, Corey N. Runkel

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interview with the BOG Director of Financial Stability about several topics related to the design and implementation of ELA in Greece

Her Majesty's Treasury Annual Report And Accounts 2020-2021, United Kingdom: Her Majesty's Treasury

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No abstract provided.

Monetary Policy Report - July 2021, Bank Of Canada/Central Bank Of Canada/La Banque Du Canada

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No abstract provided.

Best Practice Guide For Gbp Loans: The Working Group On Sterling Risk-Free Reference Rates, Bank Of England/Central Bank Of The United Kingdom

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No abstract provided.

The Bank Of England's Sterling Monetary Framework: Smf Operating Procedures, Bank Of England/Central Bank Of The United Kingdom

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No abstract provided.

Monetary Policy Report July 2021, Sveriges Riksbank

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No abstract provided.

Yale Medicine Magazine July 2021, Issue 167, Yale University. School Of Medicine

Yale Medicine Magazine - alumni bulletin and magazine

This is the July 2021 issue of Yale Medicine Magazine, issue 167. Prepared in cooperation with the alumni and development offices at the School of Medicine. Earlier volumes are called Yale School of Medicine alumni bulletins, dating from v.1 (1953) through v.13 (1965) and Yale Medicine: alumni bulletin of the School of Medicine, v.1 (1965) through v. 52, no.1. (Autumn 2017).

Allocation Of Special Drawing Rights For The Eleventh Basic Period: Draft Executive Board Decision And Managing Director Report To The Board Of Governors, International Monetary Fund (Imf), International Monetary Fund (Imf): Monetary And Financial Systems Department

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No abstract provided.

Final Gazette Notice, United Kingdom: Registrar Of Companies

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No abstract provided.

Fundamentals Vs. Policies: Can The Us Dollar's Dominance In Global Trade Be Dented?, Georgios Georgiadis, Arnaud Mehl, Helena Le Mezo, Cã©Dric Tille

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No abstract provided.

Lessons Learned: Neel Kashkari, Yasemin Esmen

Journal of Financial Crises

Neel Kashkari was the Interim Assistant Secretary of the Treasury for Financial Stability between October 2008 and May 2009. He oversaw the architecture and administration of the Troubled Asset Relief Program (TARP) during this time. This “Lessons Learned” is based on a phone interview with Mr. Kashkari.

Lessons Learned: Phillip Swagel, Yasemin Esmen

Journal of Financial Crises

Phillip Swagel was Assistant Secretary for Economic Policy at the U.S. Treasury between 2006 and 2009. During this time, he advised Treasury Secretary Hank Paulson as his chief economist, served as a member of the TARP Investment Committee, and played an important part in the conservatorship of Fannie Mae and Freddie Mac. This “Lessons Learned” is based on a phone interview with Mr. Swagel.

Lessons Learned: James Wigand, Sandra Ward

Journal of Financial Crises

A finance specialist and longtime Federal Deposit Insurance Corporation (FDIC) executive, James Wigand served as Deputy Director, Franchise and Asset Marketing, at the FDIC from 1997 to 2010, a period encompassing the global financial crisis of 2007-09. Wigand oversaw the resolution of all insured-depository institutions during the crisis, arranging acquisitions of troubled banks or liquidating them. He also acted as liaison between the chairman and board of directors of the FDIC. In 2010, in the aftermath of the crisis, Wigand was named director of the newly created Office of Complex Financial Institutions at the FDIC, an office formed under the …

Lessons Learned: Arthur Murton, Sandra Ward

Journal of Financial Crises

Arthur Murton joined the Federal Deposit Insurance Corp. in 1986 as a financial economist and rose through the ranks to become Director of the Division of Insurance and Research, a post he held from 1995 to 2013 and which he steered through the financial crisis of 2007-09. Murton participated in the important interagency discussions held on Columbus Day weekend in 2008 that led to the establishment of breakthrough programs that proved critical in stabilizing financial markets. This “Lessons Learned” summary is based on an interview with Mr. Murton about his crisis experience.

Lessons Learned: Michael Krimminger, Charles Euchner, Maryann Haggerty

Journal of Financial Crises

Michael Krimminger was Special Advisor for Policy and General Counsel at the Federal Deposit Insurance Corporation during the global financial crisis. In that role, he provided legal and policy advice on the writing and implementation of the Dodd-Frank Act, including its systemically important financial institution provisions, living wills, capital markets and capital, and structured finance requirements. He is now a partner at Cleary Gottlieb Steen & Hamilton LLP. This “Lessons Learned” is based on an interview with Mr. Krimminger.

Lessons Learned: Diane Ellis, Sandra Ward

Journal of Financial Crises

Diane Ellis served as Deputy Director, Insurance and Research, at the Federal Deposit Insurance Corp. during the financial crisis of 2007-09. The FDIC played a critical role in stabilizing financial conditions and establishing confidence in the financial markets by guaranteeing newly issued debt on a temporary basis for banks and thrifts as well as financial holding companies and eligible bank affiliates. The agency also fully guaranteed certain non-interest-bearing transaction deposit accounts. Ellis played an important role in implementing the Temporary Liquidity Guarantee Program that proved so critical in stemming the crisis. This “Lessons Learned” is based on a phone interview …

Comment Letters May Have Helped Shape Federal Reserve’S Municipal Liquidity Facility (Mlf) And Main Street Lending Program (Mslp), Steven Kelly

Journal of Financial Crises

YPFS Archive Notes highlight noteworthy content or additions to the YPFS Resource Library.

In support of the YPFS efforts to archive primary and secondary materials that shed light on financial crises, this YPFS Archive Note highlights the addition of public comment letters solicited by the Federal Reserve to evaluate two of its proposed emergency lending facilities, the Municipal Liquidity Facility (MLF) and the Main Street Lending Program (MSLP) designed to help the US economy endure the financial stresses caused by the coronavirus pandemic. The released correspondence reflects a wide array of congressional and stakeholder concerns. Ultimately, the Fed incorporated …

Hungary: Magyar Reorganizációs És Követeléskezelő Zrt (Mark Zrt.), Mallory Dreyer

Journal of Financial Crises

Hungary saw a surge in commercial real estate (CRE) lending prior to the Global Financial Crisis. By 2014, the banking sector was saddled with a high ratio of nonperforming CRE loans and repossessed property, though Hungarian banks remained solvent with high capital adequacy ratios. The central bank of Hungary, the MNB, announced the creation of an asset management company, Magyar Reorganizációs és Követeléskezelő Zrt. (MARK), to purchase nonperforming CRE assets from Hungarian banks on a voluntary basis, to clear their balance sheets and allow for increased lending. MARK was fully-owned by the MNB, which provided MARK’s share capital and a …

Spain: Sociedad De Gestión De Activos Procedentes De La Reestructuración Bancaria (Sareb), David Tam, Sean Fulmer

Journal of Financial Crises

In the wake of the Global Financial Crisis, the Spanish real estate market struggled to recover, which posed significant issues for savings banks that had an outsized exposure to the real estate sector. The Spanish government created Sociedad de Gestión de Activos procedentes de la Reestructuración Bancaria (SAREB) in 2012 to buy impaired real estate assets from troubled banks and sell them over a 15-year period using funds from an up to €100 billion ($123 billion) loan from the European Financial Stability Facility. Its mandate was “to help clean up the Spanish financial sector and, in particular, the banks that …