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Stream Clustering And Visualization Of Geotagged Text Data For Crisis Management, Nathaniel C. Crossman Jan 2020

Stream Clustering And Visualization Of Geotagged Text Data For Crisis Management, Nathaniel C. Crossman

Browse all Theses and Dissertations

In the last decade, the advent of social media and microblogging services have inevitably changed our world. These services produce vast amounts of streaming data, and one of the most important ways of analyzing and discovering interesting trends in the streaming data is through clustering. In clustering streaming data, it is desirable to perform a single pass over incoming data, such that we do not need to process old data again, and the clustering model should evolve over time not to lose any important feature statistics of the data. In this research, we have developed a new clustering system that …


Small-Signal Analysis Of Non-Isolated Ćuk Dc-Dc Converter, Lokesh Kathi Jan 2020

Small-Signal Analysis Of Non-Isolated Ćuk Dc-Dc Converter, Lokesh Kathi

Browse all Theses and Dissertations

In the future, renewable energy sources will be the primary energy sources due to non-renewable energy resources depletion. Having a sustainable energy source as an input voltage source for the electrical system is essential. Its applications can be widely used in hybrid solar-wind energy systems, electric vehicles, etc. This converter is invented and named after by Slobodan Cuk. An analysis describing a detailed steady-state operation of the non-isolated Cuk converter operating in continuous-conduction mode (CCM) is provided. The expected steady-state current and voltage waveforms across different components of the converter are analytically derived. Design equations for the converter are provided. …


Global Identification Of Human Modifier Genes Of Alpha-Synuclein Toxicity, Ishita Haider Jan 2020

Global Identification Of Human Modifier Genes Of Alpha-Synuclein Toxicity, Ishita Haider

Browse all Theses and Dissertations

Alpha-synuclein is a small lipid binding protein abundantly expressed in the brain. Lewy body or Lewy-like pathology, primarily composed of misfolded alpha-synuclein, is a pathological feature shared by several neurodegenerative disorders, including Parkinson's disease (PD). Both missense mutations and increased copy numbers of the SNCA gene, encoding the alpha-synuclein protein, have been genetically linked to autosome dominant PD. Other genetic variations affecting the expression of the SNCA gene have been associated with sporadic PD. Although the physiological function of alpha-synuclein is not well understood, its localization to plasma and vesicular membranes at the presynaptic terminals suggests a role in neurotransmission. …


Kv2.1 Channel Clustering In The Sod1-G93a Mouse Model Of Als, Joshua Christopher Harris Jan 2020

Kv2.1 Channel Clustering In The Sod1-G93a Mouse Model Of Als, Joshua Christopher Harris

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Kv2.1 channels mediate slow-activating K+ rectifier current within the membrane of spinal motoneurons (MNs), and they are known to co-localize with other synapses and ion channels. Although Kv2.1 channels are suggested to regulate MN excitability, little research has gone into investigating its potential contribution to MN-altered excitability in Amyotrophic Lateral Sclerosis (ALS). Using the male SOD1-G93A mouse model of ALS, we examined Kv2.1 cluster area and density in lumbar MNs at four key stages of disease progression. In our experiments, MNs were separated by type via SK3 immunoreactivity in order to isolate and compare the responses of disease-resistant (slow; SK3+) …


The Guardian, Week Of December 16, 2019, Wright State Student Body Dec 2019

The Guardian, Week Of December 16, 2019, Wright State Student Body

The Guardian Student Newspaper

News articles from The Guardian for the week of December 16, 2019. The Guardian is the official student-run newspaper for Wright State University. It has been published regularly since March of 1965.


The Guardian, Week Of December 9, 2019, Wright State Student Body Dec 2019

The Guardian, Week Of December 9, 2019, Wright State Student Body

The Guardian Student Newspaper

News articles from The Guardian for the week of December 9, 2019. The Guardian is the official student-run newspaper for Wright State University. It has been published regularly since March of 1965.


Investigation Of Retrieved Cardiac Devices, Anmar Salih, Iosif Papadakis Ktistakis, Spyridon Manganas, Abdul Wase, Tarun Goswami Dec 2019

Investigation Of Retrieved Cardiac Devices, Anmar Salih, Iosif Papadakis Ktistakis, Spyridon Manganas, Abdul Wase, Tarun Goswami

Biomedical, Industrial & Human Factors Engineering Faculty Publications

Damage assessment of lead and pulse generator with various exposure times is important in the development of cardiac devices. Approximately, 92.1 million patients in the US suffer from cardiovascular diseases with an estimated healthcare cost of over $300 billion and at least one million with implantable cardiac devices. These devices are complex and composed on multiple levels and present challenges while assessing the damage. However, the study on the analysis of cardiac devices may lend insight into common damage patterns and improve future cardiac devices design. The objective of this work is to perform a thorough in vivo damage assessment …


Board Of Trustees Meeting Minutes, December 5, 2019 Dec 2019

Board Of Trustees Meeting Minutes, December 5, 2019

Board of Trustees Minutes

Minutes from the Wright State University Board of Trustees Meeting held on December 5, 2019.


Investigation Of A Neuro-Stimulator Retrieved Posthumously, Megan Markl, Rodney J. Gutherie, Tarun Goswami Dec 2019

Investigation Of A Neuro-Stimulator Retrieved Posthumously, Megan Markl, Rodney J. Gutherie, Tarun Goswami

Biomedical, Industrial & Human Factors Engineering Faculty Publications

A neurostimulator was investigated in this paper posthumously. Device was presented to our anatomical gift program. Investigation was multi-fold and contained visual inspection, using an optical microscope, and mechanical and electrical testing of leads and its insulator. It was concluded that the device could have been damaged during implantation, in vivo, during removal, and/or during transportation to author’s laboratories. The damage observed on the lead insulation is similar to that which can occur due to anchoring of the lead and hardening due to oxidation. Insulation stiffness was determined to be 1/10 of new insulator. The results reported here on the …


Simulation Of Skull Fracture Due To Falls, Anthony Vicini, Tarun Goswami Dec 2019

Simulation Of Skull Fracture Due To Falls, Anthony Vicini, Tarun Goswami

Biomedical, Industrial & Human Factors Engineering Faculty Publications

This study presents novel predictive equations for von Mises stress values of bones in the frontal and lateral regions of the skull. The equations were developed based on results of a finite element model developed during this research. The model was validated for frontal and lateral loading conditions with input values mimetic to fall scenarios. Using neural network processing of the information derived from the model achieved R2 values of 0.9990 for both the stress and deflection. Based on the outcome of the fall victims, a threshold von Mises stress of 40.9 to 46.6 MPa was found to indicate skull …


The Guardian, Week Of December 2, 2019, Wright State Student Body Dec 2019

The Guardian, Week Of December 2, 2019, Wright State Student Body

The Guardian Student Newspaper

News articles from The Guardian for the week of December 2, 2019. The Guardian is the official student-run newspaper for Wright State University. It has been published regularly since March of 1965.


Accelerated Relaxation In Disordered Solids Under Cyclic Loading With Alternating Shear Orientation, Nikolai V. Priezjev Dec 2019

Accelerated Relaxation In Disordered Solids Under Cyclic Loading With Alternating Shear Orientation, Nikolai V. Priezjev

Mechanical and Materials Engineering Faculty Publications

The effect of alternating shear orientation during cyclic loading on the relaxation dynamics in disordered solids is examined using molecular dynamics simulations. The model glass was initially prepared by rapid cooling from the liquid state and then subjected to cyclic shear along a single plane or periodically alternated in two or three dimensions. We showed that with increasing strain amplitude in the elastic range, the system is relocated to deeper energy minima. Remarkably, it was found that each additional alternation of the shear orientation in the deformation protocol brings the glass to lower energy states. The results of mechanical tests …


Deep Brain Stimulation: Prediction Model For Volume Of Tissue Stimulated, Melissa Jones, Tarun Goswami Nov 2019

Deep Brain Stimulation: Prediction Model For Volume Of Tissue Stimulated, Melissa Jones, Tarun Goswami

Biomedical, Industrial & Human Factors Engineering Faculty Publications

An attempt has been made to understand deep brain stimulation in humans via marketable devices that are approved by the US Food and Drug Administration. The electrode characteristics were presented to influence the volume of tissue stimulated. Experimental data were digitized and VTS data were presented a function of electrode diameter, aspect ratio, applied current, pulse duration, voltage and frequency. Amongst other trends voltage and VTS were found to exhibit a three-stage relation, where Stage II characteristics were represented by a linear equation. It is in this stage, the VTS was found to be stable and where the most effective …


The Guardian, Week Of November 18, 2019, Wright State Student Body Nov 2019

The Guardian, Week Of November 18, 2019, Wright State Student Body

The Guardian Student Newspaper

News articles from The Guardian for the week of November 18, 2019. The Guardian is the official student-run newspaper for Wright State University. It has been published regularly since March of 1965.


The Guardian, Week Of November 11, 2019, Wright State Student Body Nov 2019

The Guardian, Week Of November 11, 2019, Wright State Student Body

The Guardian Student Newspaper

News articles from The Guardian for the week of November 11, 2019. The Guardian is the official student-run newspaper for Wright State University. It has been published regularly since March of 1965.


The Guardian, Week Of November 4, 2019, Wright State Student Body Nov 2019

The Guardian, Week Of November 4, 2019, Wright State Student Body

The Guardian Student Newspaper

News articles from The Guardian for the week of November 4, 2019. The Guardian is the official student-run newspaper for Wright State University. It has been published regularly since March of 1965.


The Guardian, Week Of October 28, 2019, Wright State Student Body Oct 2019

The Guardian, Week Of October 28, 2019, Wright State Student Body

The Guardian Student Newspaper

News articles from The Guardian for the week of October 28, 2019. The Guardian is the official student-run newspaper for Wright State University. It has been published regularly since March of 1965.


Myeloid-Derived Suppressor Cells And Pancreatic Cancer: Implications In Novel Therapeutic Approaches, Anita Thyagarajan, Mamdouh Salman A. Alshehri, Kelly L.R. Miller, Catherine M. Sherwin, Jeffery B. Travers, Ravi P. Sahu Oct 2019

Myeloid-Derived Suppressor Cells And Pancreatic Cancer: Implications In Novel Therapeutic Approaches, Anita Thyagarajan, Mamdouh Salman A. Alshehri, Kelly L.R. Miller, Catherine M. Sherwin, Jeffery B. Travers, Ravi P. Sahu

Pediatrics Faculty Publications

Pancreatic ductal adenocarcinoma (PDAC) remains a devastating human malignancy with poor prognosis and low survival rates. Several cellular mechanisms have been linked with pancreatic carcinogenesis and also implicated in inducing tumor resistance to known therapeutic regimens. Of various factors, immune evasion mechanisms play critical roles in tumor progression and impeding the efficacy of cancer therapies including PDAC. Among immunosuppressive cell types, myeloid-derived suppressor cells (MDSCs) have been extensively studied and demonstrated to not only support PDAC development but also hamper the anti-tumor immune responses elicited by therapeutic agents. Notably, recent efforts have been directed in devising novel approaches to target …


October 15, 2019 - From The President's Desk, Cheryl B. Schrader Oct 2019

October 15, 2019 - From The President's Desk, Cheryl B. Schrader

From the Desk of the President

President Cheryl B. Schrader announces her retirement from the position of President of Wright State effective on December 31. She reflects on her time and goals as President of the University. She also discusses the outcomes of the budgetary issues, and her own return to the classroom.


2019-2020 Common Data Set - Wright State University Dayton Campus, Office Of Institutional Research & Effectiveness, Wright State University, Princeton Review Oct 2019

2019-2020 Common Data Set - Wright State University Dayton Campus, Office Of Institutional Research & Effectiveness, Wright State University, Princeton Review

Common Data Set

The 2019-2020 Common Data Set of Wright State University Dayton Campus from the Princeton Review. It includes data on admissions, student enrollment, faculty, class size, financial aid and other measures, using standard definitions that aid comparisons between schools.


2019-2020 Common Data Set - Wright State University Lake Campus, Office Of Institutional Research & Effectiveness, Wright State University, Princeton Review Oct 2019

2019-2020 Common Data Set - Wright State University Lake Campus, Office Of Institutional Research & Effectiveness, Wright State University, Princeton Review

Common Data Set

The 2019-2020 Common Data Set of Wright State University Lake Campus from the Princeton Review. It includes data on admissions, student enrollment, faculty, class size, financial aid and other measures, using standard definitions that aid comparisons between schools.


Horn Mayoral Re-Election Campaign Brochure Oct 2019

Horn Mayoral Re-Election Campaign Brochure

Charles F. Horn Selected Materials

A political brochure for Charles Horn's re-election campaign for mayor of Kettering, Ohio. Horn served as mayor of Kettering from 1969-1980. Circa 1969-1980.


"Thank You, Senator Horn" Campaign Document Oct 2019

"Thank You, Senator Horn" Campaign Document

Charles F. Horn Selected Materials

A political brochure describing Charles Horn's various achievements during his term as an Ohio senator. From 1985 to 2000, Horn served in the Ohio Senate, representing the sixth district, which encompasses most of Montgomery County, including Dayton. Circa 1984-1999.


The Guardian, Week Of October 7, 2019, Wright State Student Body Oct 2019

The Guardian, Week Of October 7, 2019, Wright State Student Body

The Guardian Student Newspaper

News articles from The Guardian for the week of October 7, 2019. The Guardian is the official student-run newspaper for Wright State University. It has been published regularly since March of 1965.


Increasing Expression Of Civic-Engagement Values By Students In A Service-Learning Chemistry Course, Audrey E. Mcgowin, Rebecca Teed Oct 2019

Increasing Expression Of Civic-Engagement Values By Students In A Service-Learning Chemistry Course, Audrey E. Mcgowin, Rebecca Teed

Chemistry Faculty Publications

A service-learning course at a midsized Midwestern research university was modified over a period of six years to integrate best-practice pedagogies that have been shown to increase civic engagement by students. Best-practice pedagogies included regular interaction with community partner(s), significant time spent on the service activity, and regular reflection (written and verbal) on the implications of the service activity. Besides water quality monitoring, students performed private well water analysis, wrote multiple formal reflection papers, and presented a public talk on the results of their project that included significant discussion time with community partners. Authentic expression of civic engagement values was …


Raj Soin College Of Business Monthly Update - October 2019, Raj Soin College Of Business Oct 2019

Raj Soin College Of Business Monthly Update - October 2019, Raj Soin College Of Business

RSCob Monthly Update

The RSCoB Monthly Update highlights the activities in the college, such as, publications, new faculty, recognitions, and student accomplishments.


Aging And Rejuvenation During Elastostatic Loading Of Amorphous Alloys, Nikolai V. Priezjev Oct 2019

Aging And Rejuvenation During Elastostatic Loading Of Amorphous Alloys, Nikolai V. Priezjev

Mechanical and Materials Engineering Faculty Publications

Using molecular dynamics simulations, we investigate the effect of uniaxial elastostatic compression on the potential energy, structural relaxation, and mechanical properties of binary glasses. We consider the three-dimensional Kob-Andersen binary mixture, which was initially cooled from the liquid state to the glass phase with a slow rate at zero pressure. The glass was then loaded with a static stress at the annealing temperature during extended time intervals. It is found that the static stress below the yielding point induces large-scale plastic deformation and significant rejuvenation when the annealing temperature is smaller than a fraction of the glass transition temperature. By …


Undergraduate And Graduate Course Descriptions, 2019 Fall, Wright State University Oct 2019

Undergraduate And Graduate Course Descriptions, 2019 Fall, Wright State University

Course Descriptions

Wright State University undergraduate and graduate course descriptions from Fall 2019.


Wright State University Magazine, Fall 2019, Office Of Marketing, Wright State University, Wright Sate Alumni Association, Wright State University Foundation Oct 2019

Wright State University Magazine, Fall 2019, Office Of Marketing, Wright State University, Wright Sate Alumni Association, Wright State University Foundation

Wright State University Magazine

48-page issue of the Wright State Magazine. This magazine is published twice a year and focuses on news related to Wright State alumni, faculty, and friends of the university.


The Guardian, Week Of September 30, 2019, Wright State Student Body Sep 2019

The Guardian, Week Of September 30, 2019, Wright State Student Body

The Guardian Student Newspaper

News articles from The Guardian for the week of September 30, 2019. The Guardian is the official student-run newspaper for Wright State University. It has been published regularly since March of 1965.