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Western University

2021

Diabetes

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Sex Differences In The Intestinal Microbiome: Interactions With Risk Factors For Atherosclerosis And Cardiovascular Disease, Shamon Ahmed, J. David Spence Dec 2021

Sex Differences In The Intestinal Microbiome: Interactions With Risk Factors For Atherosclerosis And Cardiovascular Disease, Shamon Ahmed, J. David Spence

Department of Medicine Publications

Background: There are clearly sex differences in cardiovascular disease. On average, women experience cardiovascular events at an older age, and at any age, women, on average, have less atherosclerotic plaque than men. The role of the human intestinal microbiome in health and disease has garnered significant interest in recent years, and there have been indications of sex differences in the intestinal microbiome. The purpose of this narrative review was to evaluate evidence of sex differences in the interaction between the intestinal microbiome and risk factors for cardiovascular disease. Several studies have demonstrated changes in microbiota composition and metabolic profile as …