Digital Commons Network^™

The Role Of Efflux Pump Inhibitor In Enhancing Antimicrobial Efficiency Of Silver Nanoparticles And Methylene Blue As An Effective Photodynamic Therapy Agent, Yaran Allamyradov

Masters Theses & Specialist Projects

Efflux pumps are critical active transport systems utilized by cells to expel toxic substances, including antibiotics and photosensitizer complexes, thereby contributing to antimicrobial resistance. Efflux pump inhibitors (EPIs), which are compounds that obstruct the transport of molecules through these pumps, play a pivotal role in enhancing the effectiveness of antimicrobial therapies against pathogens. This study investigates the effects of the EPI reserpine on the photodeactivation rate of pathogens when used in conjunction with silver nanoparticles (Ag NPs) and methylene blue (MB), a common photosensitizer.

Our research reveals that the application of reserpine, in combination with Ag NPs and MB, leads …

Evaluating Stormwater Erosion Prevention And Sediment Control Best Management Practices Using High-Resolution Rainfall Monitoring And Field-Based Assessment Tools, Brittany Pekara

Masters Theses & Specialist Projects

Advancing stormwater management methods and technology is critical as runoff from impermeable surfaces increases with urbanization and development. Stormwater runoff is highly susceptible to contamination from non-point source pollution and causing flood impacts following rain events, which varies spatially and temporally in an urban landscape. To counteract the impacts of contamination and drainage issues, Best Management Practices (BMPs) are implemented to reduce the effects of stormwater runoff; however, the unpredictable nature of storm events can make methods for effectively monitoring impacts difficult in trying to capture first flush inputs, flood threats, and sedimentation sources. This research utilizes a highresolution rainfall …

Effect Of Glucocorticoid Blockade On Inflammatory Responses To Acute Sleep Fragmentation In Male Mice, Zim Hasan

Masters Theses & Specialist Projects

The association between sleep and the immune-endocrine system is well recognized, but the nature of that relationship is not well understood. Sleep fragmentation induces a pro-inflammatory response in peripheral tissues and brain, but it also activates the hypothalamic-pituitary-adrenal (HPA) axis, releasing glucocorticoids (GCs) (cortisol in humans and corticosterone in mice). It is unclear whether this rapid release of glucocorticoids acts to potentiate or dampen the inflammatory response in the short term. The purpose of this study was to determine whether blocking or suppressing glucocorticoid activity will affect the inflammatory response from acute sleep fragmentation (ASF). Male C57BL/6J mice were injected …

Newsletter, Wku Staff Senate

Staff Council

Newsletter created by WKU Staff Council to report on work accomplished.

A Flood Of Consequences In Louisville, Kentucky: Using Hgis To Track Refugees Impacted By The 1937 Ohio River Flood, Trevor Harry

Masters Theses & Specialist Projects

The Ohio River flood of 1937 was the most devastating flood in the recorded history of the Ohio River Valley and is commonly referred to as the “Great Flood of 1937”. In January 1937, after nearly two months of continuous precipitation, over 60% of the city of Louisville, Kentucky, was flooded and at least 23,000 residents were displaced. The purpose of this research was to document, map, and compare the pre-flood residential locations, evacuation destinations, and post-flood residential locations of African American and White Louisville refugees from the 1937 Ohio River flood. Socioeconomic information from the manuscript versions of the …

Analysis And Tritrophic Associations Of Bats, Bat Flies, And Laboulbeniales Microfungi In Kenya, Ally Willis

Masters Theses & Specialist Projects

Bats (Chiroptera) are host to diverse lineages of ectoparasitic arthropods including ticks, mites, fleas, bat bugs, and bat flies (Arthropoda). Streblidae and Nycteribiidae are families in the dipteran superfamily Hippoboscoidea, and these hematophagous ectoparasites and their host associations are relatively well studied in the American tropics but not as well in east Africa. One of the main properties of host-parasite systems is host specificity, with some Eastern Hemisphere species (Nycteribiidae) appearing to display a lower level. The morphology of bat flies may drive (or be the result of) niche partitioning on the landscape of the host. Streblid bat flies in …

“Not Like Your Abuelos”: A (Fe)Minist/Autoethnographic Approach To Vernacular Religious Belief And Traditionalization, Ciara Bernal

Masters Theses & Specialist Projects

In this thesis I explore how vernacular Mexican Catholicism is practiced, explained, and passed down within my family. I look at vernacular religious belief and traditionalization as an integrated process that impacts the practices, beliefs, and stories of my family. I include myself as a subject of this research, conducting autoethnography within each chapter. I utilize reflexive and vulnerable writing practices to accomplish this.

My overarching research questions for this thesis are: How has Mexican-Catholicism shaped the relationships, stories, and beliefs of my family members? What can Chicana feminist perspectives add to the study of vernacular religious belief and family …

Contaminant Transport Mechanisms And Source Tracking In Karst Groundwater Systems Under Agricultural Land Use, Shreya Pandey

Masters Theses & Specialist Projects

Karst areas in general face severe groundwater contamination problems that can degrade their water quality. In comparison to other landscapes, groundwater within karst regions is more susceptible to contamination. The situation gets worse when agriculture is practiced in these karst regions, because the nutrients and bacteria like nitrates and E. coli (Escherichia coli) are released into the groundwater systems which contaminate the water quality of those karst groundwater systems. This research aims to study the impacts of these contaminants, specifically nitrates and E. coli., by identifying the contaminant transport mechanisms and source tracking of these contaminants in the groundwater under …

Comprehensive Climate Vulnerability Assessment Of A Regional Karst Landscape For Hazard Mitigation Planning, Kara Brunot

Masters Theses & Specialist Projects

Climate change is the global phenomena affecting all sectors of society by creating conditions more conducive for the occurrence of extreme weather events. It is projected that the intensity and frequency of events will increase. Flooding, in particular, is projected to increase in frequency due to more intense precipitation events. Karst landscapes are especially vulnerable to climate change impacts because of their unique hydrology and geology. Karst flooding is most likely to occur from prolonged or intense rain events, which climate change will likely make more feasible. Areas are disproportionately affected by climate change due to population demographics and environmental …

Perceptions And Visual Awareness Of Urban Karst Flooding To Inform Preparedness Planning And Management Actions, Grace Hermann

Masters Theses & Specialist Projects

Awareness and perception of flooding can heavily affect how an individual or community prepares for flooding. Flood awareness can be affected by factors like past flood experience and demographics. Flood experience and demographics can affect flood awareness differently based on factors including the types and cause of flooding. Flooding in karst landscapes can vary from other types of flooding and neither perception nor awareness of karst flooding has been directly studied before. This study explored both expert and non-expert flood awareness and perception and flood policies in a karst landscape through interviews with experts, surveys, and cognitive mapping activities. The …

Development And Application Of The Sinkhole Hazard Risk Index To Inform Karst Policy And Mitigation Planning, Meghan Puente

Masters Theses & Specialist Projects

Sinkholes are geologic hazards that occur in karst landscapes and can be highly destructive and costly. Sinkhole mitigation plans and development policies are nonexistent at the federal level within the United States and vary significantly at the state level. The lack of a unified standard for sinkhole mitigation planning is partly due to a lack of available data and resources needed to assess sinkhole risk. While there are established sinkhole assessments within the literature, they focus more on the detection and prediction of sinkholes rather than a holistic approach to risk assessment. The goal of this study is to create …

The Evolution Of A Response To Smoke Within The Arthropoda, Adam Miles

Masters Theses & Specialist Projects

Many animals have a survival instinct to flee in response to fire, but do they respond to smoke alone? Many arthropods respond to fire or smoke by moving in the opposite direction (a negative taxis) to obtain shelter. At the species level, taxa that have adapted a behavioral response to fire increase their fitness. This response behavior has been observed in many terrestrial arthropods. Still, the behavior is currently unknown for marine, aquatic, or cave arthropods, which are atypically exposed to smoke or fire. This project assesses how often behavioral adaptation to smoke avoidance may have evolved within Arthropoda. Twenty-two …

Parameter Estimation For Stroke Patients Using Brain Ct Perfusion Imaging With Deep Temporal Convolutional Neural Network, Shake Ibna Abir

Masters Theses & Specialist Projects

Acute ischemic stroke, caused by cerebral artery blockage, is a leading cause of long-term disability and mortality. Effective management relies on accurate, timely assessments from neuroimaging data. Computed tomography perfusion (CTP) imaging is crucial in evaluating stroke patients, offering detailed maps of cerebral perfusion to identify irreversibly damaged tissue and at-risk areas. This detailed assessment is essential for informed therapeutic decisions.

Key perfusion parameters derived from CTP imaging, including cerebral blood volume (CBV), cerebral blood flow (CBF), time to peak (TTP), and mean transit time (MTT), are crucial for understanding the extent and nature of cerebral ischemia, providing valuable insights …

Assessing Regional Responsibility Of Plecoptera (Stoneflies) Across Two U.S. Fish And Wildlife Service Regions, Josie Griffith

Masters Theses & Specialist Projects

Developing an objective metric to designate taxa that are the responsibility of the region is imperative for the proper allocation of conservation funding. This project focused on stoneflies (Order Plecoptera), an imperiled group of aquatic insects at the global scale, in two U.S. Fish and Wildlife Service regions. At the regional scale, a baseline designation of Regional Species of Greatest Conservation Need (RSGCN) was applied to each species where their range included at least 75% of states within either the Midwestern or Northeastern regions. Two sets of data were accumulated for each RSGCN. One, distributional information was collected from valid …

Alfred Russel Wallace Notes 31. Wallace’S Personal Copy Of “Life Of Alexander Von Humboldt.”, Charles H. Smith

Faculty/Staff Personal Papers

Alfred Russel Wallace owned a personal copy of the two-volume 1873 English edition of the Life of Alexander von Humboldt, now held by the library of the Linnean Society of London. Each volume is highly annotated, and the nature of these notes, and their several-directioned importance, is here discussed.

Effects Of Remote Versus In-Person Training On Metabolic Profiles And Body Composition Of Physically Inactive Adults. Randomized Clinical Trial, Jhonatan Peña, Willlian Martin, Luis Cardozo, John F. Rodriguez, Cristian C. Peña, Luisa Cardenas, Luis Andres Tellez Tinjaca

International Journal of Exercise Science

International Journal of Exercise Science 17(4): 1016-1025, 2024. The COVID-19 pandemic has pushed the population to adopt increasingly sedentary lifestyles. Faced with this problem, remote training appears as a practical and inexpensive strategy to promote physically active lifestyles. The aim of this research was to compare the effects of remote versus in-person training on metabolic profiles and body composition of physically inactive adults. This research was conducted through a randomized, single-blind clinical trial with balanced block randomization. The sample consisted of 30 physically inactive subjects of both sexes between 18 and 30 years of age. The sample was selected using …

Skills And Hills: Factors That Influence Women’S And Non-Binary College Students’ Decisions To Commute Via Bicycle, Emily Dzieniszewski, Ashley N. Myers, Lucas D. Elliott, Melissa Bopp

International Journal of Exercise Science

International Journal of Exercise Science 17(8): 1003-1015, 2024. College students, who actively travel in the forms of walking and/or bicycling, have shown a wide range of physical and mental health benefits. Despite the known benefits of bicycling, participation is influenced by various demographics, including gender identity, sexual orientation, and race/ethnicity. Universities have the potential to promote active travel participation to all populations. The study aimed to understand the environmental and social factors influencing female students’ decision to commute via bicycle in a university setting. A volunteer sample of female college students (n=153) were surveyed to identify common themes from the …

The Effect Of Resisted Sprint Training On Acceleration: A Systematic Review And Meta-Analysis, Elizabeth K. Aldrich, Katherine Sullivan, Jonathan E. Wingo, Michael R. Esco, James Leeper, Mark T. Richardson, Lee J. Winchester, Michael V. Fedewa

International Journal of Exercise Science

International Journal of Exercise Science 17(6): 986-1002, 2024. Resisted sprint (RS) training, such as sled or parachute towing, is commonly used for sprint training among field sport athletes. While RS training is frequently employed by athletes and coaches, there is little research on its benefits, especially compared to unresisted running (UR) training programs with similar training volumes. This systematic review and meta-analysis compared the effectiveness of RS training on acceleration compared to UR training. Potential sources were limited to peer-reviewed articles published in English prior to June 12, 2022, and gathered from the EBSCOhost, PubMed, and Web of Science online …

Thompson, Archibald, 1736-1808 (Sc 3730), Manuscripts & Folklife Archives

Manuscript Collection Finding Aids

Finding aid for Manuscripts Small Collection 3730. Journal of Archibald Thompson, a native of Ireland and a Revolutionary War veteran. He records many family births and marriages, his own family’s various relocations in Virginia and in Monroe (formerly Cumberland) County, Kentucky, and miscellaneous accounts and transactions. Includes a typescript and name index prepared by Sandra K. Gorin under the title “The Archibald Thompson Journal" (Click on "Additional Files" below for scan, made available with her permission).

Newsletter, Wku Staff Senate

Staff Council

Newsletter created by WKU Staff Council to report on work accomplished.

Identifying Sudden Cardiac Arrest Risk In Adolescent Male Athletes, Alexis Sattler, Susan Rozzi

International Journal of Exercise Science

International Journal of Exercise Science 17(2): 874-886, 2024. The purpose of the study was to determine the prevalence of sudden cardiac arrest (SCA) risk factors in high school (HS) athletes. Thirty-three male soccer players from a public HS in the southeastern United States (ages 14-17) self-reported survey data. Participants reported demographic, lifestyle, heart health, COVID-19 history, and symptoms indicative of SCA risk. An electrocardiogram (ECG) assessed heart rate (HR), rhythm, and electrical activity. Resting HR and blood pressure (BP) were measured with a BP monitor. The association between COVID-19 history, HR, and BP were calculated. Participants were divided into ECG …

Motivation Matters: Understanding The Antidepressant Mechanism Of Physical Activity Among Young Adults, Jessica E. H. Ryan, Travis R. Menuz, Megan E. Ames

International Journal of Exercise Science

International Journal of Exercise Science 17(5): 861-873, 2024. A negative association between physical activity and depressive symptoms is consistently reported within scientific literature and physical self-concept has been suggested to mediate this pathway. However, for whom these associations are strongest remains poorly understood, and little is known about how other psychosocial factors might be implicated. Consequently, we examined how various exercise motivations, specifically appearance, physical health, and mental health, might moderate the indirect effect of physical activity on depressive symptoms through physical self-concept. Canadian young adults (N = 496, Mage = 20.36, SD = 1.87) completed an online questionnaire. …

How An Ijes Working Group Grappled With The Complexities Of Three Letters—Dei—With The Goal To Broaden Inclusion And Representation In Exercise Science Research, Dustin W. Davis, Matthew J. Garver, Jafra Thomas, James W. Navalta, Shannon Siegel, Joel D. Reece, Jill M. Maples

International Journal of Exercise Science

International Journal of Exercise Science 17(8): 852-860, 2024. A self-study of International Journal of Exercise Science (IJES) publications from 2008 through 2021 revealed a sex-data gap in participant and corresponding author representation. This finding prompted the creation of the IJES Working Group for Opportunity, Representation, and Diverse Perspectives. We are a collaborative team of authors, reviewers, and editors, spanning both rural and urban teaching- and research-focused institutions, who assembled regularly starting in September 2023. The goal was to contemplate potential challenges and opportunities around diversity, equity, and inclusion (DEI), elicit discourse, and broaden inclusion and representation in exercise science research. …

The Use Of Musculoskeletal Fitness Measures As Indicators Of Performance In Police Occupational Tasks, Elisa F.D. Canetti, Robin Marc Orr, William Brown, Ben Schram, Robert G. Lockie, J. Jay Dawes

International Journal of Exercise Science

International Journal of Exercise Science 17(4): 819-830, 2024. Fitness testing is employed by some law enforcement agencies to assure performance in occupational tasks. The aim of this study was to investigate associations between musculoskeletal fitness assessment scores and performance in police occupational tasks. Retrospective data from 106 law enforcement officers who completed five musculoskeletal fitness assessments (vertical jump (VJ), hand grip strength, leg back dynamometer, 1-minute push-ups and sit-ups) and three routine occupational tasks (1.22m fence jump (FJ), 8.5m victim drag (VD) with 101kg and a get-up (GU)) were collected. A standard multiple regression was performed to determine if the …

Normative Hamstrings And Quadriceps Isometric Strength Values And Hamstrings-Quadriceps Asymmetry In Healthy Collegiate Soccer And Basketball Players, Oluwatoyosi Owoeye, Davie Mulenga, Jemma Kim, Anthony Breitbach, Jamil Neme

International Journal of Exercise Science

International Journal of Exercise Science 17(4): 768-778, 2024. The objectives of this study were to report weight-normalized, sex- and sport-stratified normative values for hamstrings and quadriceps isometric strength in collegiate soccer and basketball players using a low-cost hand-held dynamometer and assess the prevalence of “substantial” hamstrings-quadriceps (H/Q) ratio strength imbalance (<0.6) among players. Ninety-four healthy collegiate male and female soccer and basketball players (age range: 18–24 years) were examined for baseline isometric hamstrings and quadriceps strength using a handheld isometric dynamometer with standardized and valid protocols. For soccer, the mean (95%CI) weight-normalized peak isometric strength values (considering dominant limbs) were 3.29 (2.90 to 3.64) N/kg (hamstrings) and 5.48 (4.96 to 6.00) N/kg (quadriceps) in male players and 2.62 (2.39 to 2.85) N/kg (hamstrings) and 4.55 (4.14 to 4.96) N/kg (quadriceps) in female players. For basketball, the mean (95% CI) peak strength values were 2.97 (2.72 to 3.21) N/kg (hamstrings) and 4.89 (4.44 to 5.33) N/kg (quadriceps) in male players and 2.48 (2.15 to 2.80) N/kg (hamstrings) and 4.21 (3.54 to 4.87) N/kg (quadriceps) in female players. The prevalence of substantial H/Q strength imbalance was 37% (95%CI: 24% to 52%) in soccer and 44% (95%CI: 29% to 60%) in basketball players. This study is first to provide normative values for peak isometric hamstrings and quadriceps strength using a low-cost hand-held dynamometer. The normative database from this study is valuable to coaches, sports medicine professionals, exercise scientists and other stakeholders to inform injury prevention, rehabilitation progression, return to play decisions and performance goals in collegiate soccer and basketball players.

Acute Effects Of Exercise At Different Temperatures On Clinical Symptoms And Nasal Blood Flow In Patient With Allergic Rhinitis: A Randomized Crossover Trial, Kanphatson Kerdkaew, Wannaporn Tongtako

International Journal of Exercise Science

International Journal of Exercise Science 17(3): 779-793, 2024. Allergic rhinitis (AR) affects the nose and is triggered by allergens. However, no research studies have analyzed the acute effect of aerobic exercise at different temperatures in AR patients. This study was to determine the acute effect of aerobic exercise at different temperatures on rhinitis symptoms and nasal blood flow (NBF) in AR patients. Fifteen AR patients aged 18–24 years were randomized in a crossover fashion into two protocols: 60 minutes of aerobic exercise at temperatures of 25 °C and 34 °C. The NBF, rhinitis symptoms, peak nasal inspiratory flow (PNIF), fractional …

Validity Of A Heart Rate Monitor For Heart Rate Variability Analysis During An Orthostatic Challenge, Christian Soto Catalan, Alain Steve Comtois Phd, David Martin, Suzzane Leclerc

International Journal of Exercise Science

International Journal of Exercise Science 17(2): 810-818, 2024. Heart rate variability (HRV) is used as a measure of autonomic nervous system (ANS) function and is based on heart rate (HR) beat-to-beat time interval variance analysis. Various techniques are used for recording HR, however, few studies have compared Holter-type recordings vs HR monitors (HRM) during an orthostatic challenge. OBJECTIVES: Compare HRV measures from an electrocardiogram (ECG) Holter and a HRM as a tool for investigating ANS response for post-concussion rehabilitation follow-up. METHODS: Twenty-seven participants (n = 27; 15 females, 12 males), 18 to 35 years old, non-smoking, no history of …

Empowerher: A Pilot Study To Increase Physical Activity And Strength Through Powerbuilding, Aspen E. Streetman, Murry T. Streetman, Halle N. Brin, Emily L. Mailey, Katie M. Heinrich

International Journal of Exercise Science

International Journal of Exercise Science 17(8): 750-767, 2024. Engaging in empowering exercise develops movement competency (MC) and strength and supports physical health, mental well-being, and quality of life. Powerbuilding combines powerlifting and bodybuilding to increase physical activity (PA), MC, and strength. To our knowledge, powerbuilding has not been explored as an exercise intervention. This pilot study investigated the impact of an eight-week powerbuilding intervention on women’s PA, MC, strength, and empowerment. Eighteen women aged 25.1±9.8 with no powerbuilding experience participated in the intervention, meeting three times weekly for one hour. PA and MC were assessed pre- and post-intervention. Three-repetition maximum …

The 2024 International Journal Of Exercise Science Position Stand On Inclusion, James W. Navalta, Dustin W. Davis, Jafra Thomas, Matthew J. Garver, Shannon Siegel, Joel D. Reece, Jill M. Maples

International Journal of Exercise Science

International Journal of Exercise Science 17(8): 730-749, 2024. The International Journal of Exercise Science (IJES) Working Group for Opportunity, Representation, and Diverse Perspectives was tasked with developing a position stand to provide guidance in critical areas of inclusion. We present to authors, reviewers, and all readership IJES ideals to utilize in practice. Key points are presented, followed by a deeper look with greater explanation into the areas of inclusive language, diversity and inclusion in research, and accessibility. The same approach is presented for the areas of age, disability status, gender identity and sexual orientation, race, and ethnicity with attention to …

Hayes, Eugenia Mary (Blakey), 1905-1992 (Mss 764), Manuscripts & Folklife Archives

Manuscript Collection Finding Aids

Finding aid only for Manuscripts Collection 764. Primarily genealogical research collected by Eugenia Hayes on her ancestors in the Blakey, King, Morris, Cowherd and related families.