Digital Commons Network^™

Vigorous Physical Activity And The Length Of Telomeres Across Levels Of Bmi In 4,458 U.S. Adults, Christina M. Blackmon, Larry A. Tucker

International Journal of Exercise Science: Conference Proceedings

Telomere length is an index of cellular aging. Longer telomeres are predictive of longer life. Healthy lifestyles are associated with longer telomeres. PURPOSE: This study focused on the relationship between time spent in vigorous physical activity (PA) and leukocyte telomere length (LTL) in 4,458 randomly selected U.S. adults, 20-69 years old. METHODS: The association was studied using data collected as part of the National Health and Nutrition Examination Survey (NHANES) and a cross-sectional design. Vigorous physical activity was indexed by calculating total time spent jogging or running per week (Jog/Run/Wk). Weekly jog/run time was calculated by multiplying days of jog/run …

Strength Training And Biological Aging: Telomere Evidence From A National Sample Of 4,813 U.S. Adults, Carson J. Bates, Larry A. Tucker

International Journal of Exercise Science: Conference Proceedings

Telomere length is an index of biological aging. As humans age, their telomeres become progressively shorter. Additionally, healthy lifestyle practices are associated with longer telomeres and unhealthy habits predict shorter telomeres. PURPOSE: This study evaluated the association between weekly time spent strength training (ST) and leukocyte telomere length (LTL) in 4,813 randomly selected U.S. adults, 20-69 years old. METHODS: Data collected as part of the National Health and Nutrition Examination Survey (NHANES) was employed to answer the research question using a cross-sectional design. The findings are generalizable to the U.S. adult population. Time spent ST per wk was calculated by …

The Effect Of Quercetin On Bone Turnover Markers, Inflammatory Markers, And Bone Mineral Density In Postmenopausal Women: A Double-Blind Placebo-Controlled Investigation, Alyssa R. Bailly, Garrett M. Hester, Robert J. Buresh, Michaela M. Alesi, Jeremy B. Ducharme, Christine M. Mermier, Trisha A. Vandusseldorp

International Journal of Exercise Science: Conference Proceedings

Maintaining optimal bone health prevents major bone disorders (e.g., osteoporosis) and prolongs longevity. Quercetin is a plant-based flavonoid that is suggested to have anti-inflammatory effects and may improve bone health. PURPOSE: To investigate the effects of quercetin supplementation over 90-days on prominent bone turnover markers (BTMs), inflammatory markers, bone mineral density (BMD), body composition, and physical functioning in postmenopausal women. METHODS: Thirty-three healthy, nonosteoporotic, postmenopausal women (59.2±7.0 years) participated in a double-blind, placebo-controlled investigation. Participants were randomized into one of two supplement groups: 1) 500 mg of quercetin (QUE) once daily or 2) 500 mg of methylcellulose (placebo; …

Validity Of A Novel Sensor For Noninvasive Measurement Of Core Body Temperature In Humans During Exercise, Colin Atkins, Grace Handler, Casandra Mendez, Alvin Molina, Lauryn Outlaw, Matthew G. Becker, Matthew M. Schubert

International Journal of Exercise Science: Conference Proceedings

The measurement of core body temperature during exercise can be useful for athletic performance and the prevention of heat-related illness. Non-invasive sensors have been developed for the measurement of core body temperature, but more data on their validity and reliability is needed before they can be recommended for widespread adoption. PURPOSE: The purpose of the present study was to evaluate a noninvasive core temperature sensor (T_Core) during exercise compared to an ingestible thermistor (T_Pill). METHODS: Twenty men and women (25 ± 4 years) participated in this study. Participants completed 20 minutes of exercise at 60% age-predicted …

Handgrip, Pinch Grip, And Reaction Time Of Firefighters And Police Officers, Zarmina Amin, Galilea Gutierrez, Yangmi Kang, Larissa True

International Journal of Exercise Science: Conference Proceedings

Handgrip strength (HGS) and pinch grip strength are related to proper hand function. Quick and accurate reaction to stimuli is critical to perceptual-motor abilities. Firefighters (FF) and police officers (PO) are routinely involved in high-intensity emergency tasks that require HGS, pinch grip strength, and reaction time (RT). PURPOSE: The purpose was to examine differences in bimanual HGS, bimanual pinch grip strength, and dominant hand RT between FF and PO in the Southwest. METHODS: Anthropometric measures of the hand were taken. HGS was measured using a hand dynamometer. Tip, key and palmar pinch grip strength were measured using a …

Heart Rate Variability Threshold Evaluation During Arm And Leg Cycling, Kaylee Allen, Nicolas Clark, David H. Fukuda Ph.D.

International Journal of Exercise Science: Conference Proceedings

Background: The Heart Rate Variability Threshold (HRVT) is a point of deflection in heart rate variability assessed during incremental exercise to exhaustion. This threshold is thought to represent a shift in the autonomic balance. Purpose: The purpose of this study was to evaluate (HRVT) during arm (AC) and leg cycling (LC). Methods: There were twenty-three participants (age: 23.3±4.7 years; height: 168.6±7.5 cm; weight 66.8±8.9 kg). Participants completed two graded exercise tests, one for AC and one for LC on different days. They wore a heart rate monitor which recorded R-R intervals. The test performed was a graded exercise test to …

Measurement Of Physical Activity With Wrist-Worn Actigraph Gt3x+ In Older Women, Michal T. Smith, Erin E. Kishman, Robert G. Weaver, Jennifer R. O'Neill, Xuewen Wang

International Journal of Exercise Science

International Journal of Exercise Science 15(7): 1538-1553, 2022. Higher wear compliance has been seen with wrist placed accelerometers versus hip placed. Performance of wrist placed ActiGraph GT3X+ accelerometer (GT3X+, ActiGraph LLC, Pensacola, FL) in assessing physical activity (PA) remains unclear. PURPOSE: This study examined GT3X+’s performance in measuring PA energy expenditure (PAEE) and classifying PA intensity in older women. METHODS: Women [n = 89, age = 65.6 (4.3)] wore GT3X+ and SenseWear Armband Mini (SWAM, BodyMedia Inc. Pittsburgh, PA) for 2 weeks. Concurrently, doubly labeled water (DLW) determined total daily energy expenditure (TDEE). Resting energy expenditure (REE) was determined …

Cognitive Function Is Unaffected During Acute Hypoxic Exposure But Was Improved Following Exercise, Jasmin R. Jenkins, Owen F. Salmon, Cory M. Smith

International Journal of Exercise Science

International Journal of Exercise Science 15(5): 1481-1491, 2022. To investigate the effects of two levels of acute hypoxic exposure and exercise compared to normoxia on the Stroop color word test. A total of 14 (4 females and 10 males) active participants with a self-reported (mean±SEM) 8.54±1.44 h/week of physical activity, performed a 3-repetition maximum hex/trap bar deadlift, Hand-Release Push-Up, and Leg Tuck events from the Army Combat Fitness Test at normoxia and normobaric hypoxia of fraction of inspired oxygen (FiO₂) of 16% and 14.3%. The Stroop color-word test was administered on a touch screen device before and after …

Effects Of Oxidative Damage During Ruesi Dadton Exercise In Mild Cognitive Impairment: A Randomized Controlled Trial, Phaksachiphon Khanthong, Ananya Dechakhamphu, Kusuma Sriyakul, Aungkana Krajarng, Chuntida Kamalashiran, Parunkul Tungsukruthai

International Journal of Exercise Science

International Journal of Exercise Science 15(3): 1528-1537, 2022. This study aimed to investigate the effect of biomarkers of oxidative stress (OS) in 8-isoprostane (8-iso) and 8-hydroxy-2'–deoxyguanosine (8-OH-dG) on mild cognitive impairment (MCI) during a 12-week Ruesi Dadton (RD) exercise. A total of 274 enrolled participants were classified into blocks based on age and formal educational years, and randomly assigned into two groups: RD and control (CON). The participants’ cognitive functions were tested using Mini-Mental State Examination and Montreal Cognitive Assessment (MoCA) scores to screen for MCI. Urine samples of approximately 30 mL were collected from both groups pre- and post-intervention. …

Neuromuscular Fatigability Associated With Different Pacing Strategies During An Ultra-Endurance Pull-Up Task: A Case Study, Jenny Zhang, Arash Khassetarash, Guillaume Y. Millet, Saied J. Aboodarda

International Journal of Exercise Science

International Journal of Exercise Science 15(3): 1514-1527, 2022. While neuromuscular fatigability has been previously characterized after running and cycling, no study has investigated an ultra-endurance upper body task. In preparation for a world record attempt, three pacing strategies to perform 1980 pull-ups in 6 hrs were compared during independent sessions: fast pace, long recovery (FL), fast pace, multiple short recoveries (FMS), and slow pace, no recovery (SN). Elbow flexion maximal voluntary contraction (MVC) force, grip strength, peripheral fatigue, and biceps brachii electromyography were quantified every 330 pull-ups and during recovery, alongside heart rate, perceived effort, and arm muscle pain. In …

Is There A Relationship Between Foot Reaction Time And Ankle Frontal Plane Torque In Female Soccer Athletes: A Pilot Study., Maggie Feehan, Andrew Shim, Guilherme M. Cesar, Amy Burggraff

International Journal of Exercise Science

International Journal of Exercise Science 15(1): 1506-1513, 2022. The purpose of this study was to determine if a relationship existed between foot reaction time and ankle frontal plane peak torque in female soccer athletes. A one-shot case study design was selected for this investigation. Seventeen female college athletes volunteered to participate. Right and left foot reaction time measurements were assessed using 3x4 switch mats interfaced with a precise timing counter. Participants stood in front of the mat with eyes closed and responded to the auditory stimulus by touching the mat as fast as possible with their foot. Two trials were …

The Triple Step In Recreational Swing Dancers: A Kinematic Analysis, Meredith D. Wells, Feng Yang

International Journal of Exercise Science

International Journal of Exercise Science 15(1): 1492-1505, 2022. Swing dancing is gaining popularity, yet our biomechanical understanding of swing dance remains poor, creating barriers to the development of training protocols and evaluation of performances. This study aimed to determine whether dancing with or without a partner affects the lower extremity kinematics of the triple step, and if the kinematics differ among the three steps of the dance element. Eight recreational swing dancers completed three sets of rightward triple steps with and without a partner. The angles in the sagittal, frontal and transverse planes were determined for bilateral lower limb joints …

Convergent Validity Of The Short Recovery And Stress Scale In Collegiate Weightlifters, Alec R. Perkins, S. Kyle Travis, Satoshi Miziguchi, Michael Stone, Kevin Breuel, Michael Kellmann, Caleb Bazyler

International Journal of Exercise Science

International Journal of Exercise Science 15(6): 1457-1471, 2022. The purpose of this study was to determine whether changes in collegiate weightlifters’ external training load, biochemical markers, and jumping performance correlate to changes in items of the Short Recovery and Stress Scale (SRSS) throughout four microcycles. Twelve well-trained weightlifters (8 males, 4 females; age 24.30 ± 4.36 yr; height 170.28 ± 7.09 cm; body mass 81.73 ± 17.00 kg) with at least one year of competition experience participated in the study. Measurements included hydration, SRSS, biochemical analysis of blood (cortisol [C], creatine kinase [CK]), and unloaded and loaded squat jumps (SJ), …

The Role Of Gut Health In Parkinson’S Disease: The Impact On Motor Symptoms And Fitness Levels, Kaylie Zapanta, E Todd Schroeder, Beth E. Fisher

International Journal of Exercise Science: Conference Proceedings

While Parkinson’s disease (PD) has traditionally been considered a central nervous system disease, recent groundbreaking research argues that PD symptomology is influenced by gut microbiota alterations (dysbiosis).¹ People with PD suffer from dysbiosis,^2-6 and gut symptoms characteristic of dysbiosis, like constipation.^7,8 Given this evidence, strategies that improve gut health in PD are warranted. One possible strategy is exercise. In non-PD populations, fitness status is linked to gut health,^9-13 and exercise which increases fitness status improves the gut.^14-19 It is now known that exercise improves motor symptoms in PD,^20-23 but the gut may be a …

The Two-Dimensional Relationship Between Ground Reaction Force Vector And Knee Axis Of Rotation Reflect Knee Loading Deficits During Squatting Post-Aclr, Jiaqi Wang, Susan Sigward

International Journal of Exercise Science: Conference Proceedings

PURPOSE

Individuals post-anterior cruciate ligament reconstruction (ACLr) perform reduced knee extensor moments (KEM) during squats by shifting weight to the non-surgical (NSx) limb ¹ or by shifting demands from the knee to hip ^1,2. These compensations occur without observable differences in joint angles by small adjustments in the center of pressure (COP). This makes them difficult to detect and may contribute to their persistence. Differences between limbs in COP position suggest that individuals adjust the relationship of the ground reaction force vector (GRFv) relative to the joint center to redistribute the loading demands in the surgical limb ³. …

Stimulated Muscle Contractions Regulate Membrane-Bound And Soluble Tlr4 To Prevent Lps-Induced Signaling And Myotube Atrophy In Skeletal Muscle Cells, Jeremy B. Ducharme, Zachary J. Fennel, Zachary J. Mckenna, Quint N. Berkemeier, Michael R. Deyhle

International Journal of Exercise Science: Conference Proceedings

Toll-like receptor 4 (TLR4) activation by lipopolysaccharides (LPS) contributes to chronic inflammation and causes upregulation of muscle atrophy signaling pathways. Exercise can suppress LPS/TLR4 axis activation by reducing the expression of TLR4 on immune cells. It is unknown how this regulation occurs, and it is not clear how exercise affects TLR4 on skeletal muscle. PURPOSE: To uncover the nature and mechanisms by which exercise affects TLR4 expression and intracellular signaling using cell culture models and human experiments. METHODS: C2C12 myotubes were subjected to electrical pulse stimulation (EPS) with and without subsequent treatment with 500 ng/mL lipopolysaccharide (LPS) along with …

Sex Differences In Hemodynamic Response To High Intensity Interval Exercise (Hiie), Leah N. Coe

International Journal of Exercise Science: Conference Proceedings

There are sex differences in the cardiorespiratory and hemodynamic response to exercise due to inherent differences in heart size, blood volume, and hemoglobin mass that elicit a higher VO₂max in men versus women. These alterations in cardiac structure and function may mediate changes in VO₂max per the Fick Equation. However, existing data are inconclusive on whether sex differences in training responsiveness exist. PURPOSE: The purpose of this study is to investigate potential sex differences in the hemodynamic response to HIIE. If men and women reveal discrepant cardiovascular responses to HIIE, this may partially mediate sex differences …

Inter-Step Height Variation Of Stairways And Observations Of Fall-Related Events, Chayston B. Brown, Shandon Poulsen, Chris Dakin, Sara Harper, Tyson Barrett

International Journal of Exercise Science: Conference Proceedings

INTRODUCTION: Variation in step height within a stairway could negatively impact safe stairway negotiation by decreasing step height predictability, and consequently, increasing stair users’ fall risk. Unfortunately, inter-stairway step height variability is common, particularly in older stairways, but its impact may be lessened by highlighting steps’ edges using high-contrast stripes on the top front edge of each step. Such contrast enhancement may draw greater attention to the steps’ edges and potentially enhance the precision of the edge’s estimated location. PURPOSE: To determine (1) if fall-related events are associated with greater inter-step height variation, and (2) if such fall-related events are …

The Impact Of Squat Velocity On Force, Power, And Muscle Activity, Kyle D. Puccini, James Baldonado, Bonnie Yee, Christie R. O'Hara

International Journal of Exercise Science: Conference Proceedings

The squat is a thoroughly examined movement pattern and commonly used in sport performance training protocols, rehabilitation programs, and recreational exercise. Previous research measuring absolute strength has shown hamstring muscle activity in a six-repetition max barbell back squats. PURPOSE: The purpose of this study is to examine the effects of varying squat velocities (25, 50, 75 deg/s) on force, power, and the activation of the quadricep and hamstring muscles. Using a single-blind randomized research design, we hypothesized that hamstring muscle activity will increase at faster squat velocities. Our secondary hypothesis is that peak power will occur at 50 deg/s and …

Impact Of Mask Wearing On Post-Exercise Hemodynamics, Payton J. Price, Zachary Zeigler, Luke Heikka, Adarius West, Sofia Harman, Anthony Acevedo

International Journal of Exercise Science: Conference Proceedings

As the guidelines regarding COVID-19 regressed, many fitness centers established regulations requiring mask-wearing during exercise. Data suggest that the impact of a mask during exercise has minimal effects on exercise hemodynamics. The post-exercise period has been described as a window of opportunity to lower blood pressure, a phenomenon called post-exercise hypotension. The impact of wearing a mask on post-exercise hemodynamics is unknown. PURPOSE: The purpose of this study was to examine the impact of mask-wearing during exercise on post-exercise hemodynamics. METHODS: Nine total participants aged 18-30 yr were recruited for this experimental cross-over study. This within-subject design involved …

Muscle Mitochondrial Function At Different Phases Of The Menstrual Cycle, Brandon S. Pfeifer, Briell King, Erin Atkinson, Chad R. Hancock, Robert D. Hyldahl

International Journal of Exercise Science: Conference Proceedings

The effect of menstrual cycle (MC) phase on muscle recovery from damage has been studied using markers of strength and soreness, but remains inconclusive. Mitochondrial function is essential for muscle recovery, and has been found to be influenced by estradiol (E2). Understanding the relationship between MC phase and mitochondria can provide further insight into women’s muscle health. The PURPOSE of this study was to determine how MC phase affects markers of muscle damage and recovery, with emphasis on mitochondrial function, following electrically-stimulated muscle contractions. METHODS: 22 premenopausal females were recruited and split into two groups, early follicular (EF) and …

Exercise And Esr1 Control Mitochondrial Content And Function To Regulate Adiposity, Alice M. Ma, Nicole Lee Yang, Alexander R. Strumwasser, Zhenqi Zhou, Andrea L. Hevener

International Journal of Exercise Science: Conference Proceedings

Mechanisms that underlie adipose tissue remodeling to enhance metabolic health in response to exercise training remain inadequately understood. PURPOSE: We utilized mouse genetics and human GWAS to determine the impact of exercise training on mitochondrial DNA copy number, and interrogate the relationship between Esr1 and adipose tissue health. METHODS: We performed RNAseq on adipose tissue from 100 strains of inbred mice following exercise training and determined mitochondrial content by qPCR. We performed deep phenotyping of mice harboring conditional Esr1 overexpression selectively in adipose tissue. Adipose specific Esr1 overexpression and control mice were fed a high fat diet and …

“Cheating” In A Fast By Exercising After A Snack, Katelynn Hales, Landon Deru Ms, Mba, Atc, Bruce Bailey Phd, Facsm,, Hi'ilei Chan, Jake Moss

International Journal of Exercise Science: Conference Proceedings

As the prevalence of chronic diseases has increased, research has emerged supporting the utility of intermittent fasting in managing certain health conditions. Despite potential benefits, adhering to a fasting regimen can be difficult. PURPOSE: The purpose of this study was twofold. The first purpose was to describe how consuming a modest snack prior to exercise influences plasma glucose, beta-hydroxybutyrate and hunger in reference to fasting with and without exercise. The second purpose was to examine how exercising in a fasted state influences plasma glucose, beta-hydroxybutyrate and hunger. METHODS: A randomized crossover design with counterbalanced treatment conditions was used to compare …

A Pilot, Virtual Exercise Intervention Improves Health And Fitness During The Covid-19 Pandemic, Alexander H.K. Montoye, Makenzie J. Rajewski, Drew A. Marshall, Sylvia E. Neph, Karin A. Pfeiffer

International Journal of Exercise Science

International Journal of Exercise Science 15(7): 1395-1417, 2022. Physical activity levels are low in individuals with chronic disease (e.g., obesity) and have worsened during the COVID-19 pandemic. Purpose: Our pilot study tested a virtual exercise intervention for rural-dwelling adults with chronic disease from January-April 2021 for changes in mental health, physical fitness, and physical activity and for intervention fidelity. Methods: Participants (n = 8 [7 female]; age = 57.5 ± 13.8 years, body mass index = 38.2 ± 8.0 kg/m²) completed an exercise intervention led virtually by collegiate health science majors. Participants attended two 60-minute sessions/week for …

Changes In Fitness-Fatness Index Following A Personalized, Community-Based Exercise Program In Physically Inactive Adults: A Randomised Controlled Trial, Abbey M. Jones, Lance C. Dalleck, Ryan M. Weatherwax, Joyce S. Ramos

International Journal of Exercise Science

International Journal of Exercise Science 15(4): 1418-1429, 2022. Fitness-fatness index (FFI) is used to identify those at high risk of developing type 2 diabetes and cardiovascular events. It is measured as the ratio between an individual’s cardiorespiratory fitness (CRF) and waist-to-height ratio. Studies suggest that CRF and waist-to-height ratio are modifiable and can be improved by exercise. However, there is limited evidence surrounding a personalized approach to exercise prescription. This study investigated the impact of a 12-week personalized exercise program on FFI among sedentary individuals. It was hypothesized that the intervention would be effective in improving FFI in this cohort. …

Exercise Based Cancer Rehabilitation Program Improves Phase Angle In Breast Cancer Survivors, Trevor Short, Cheri Teranishi-Hashimoto, Paulette Yamada

International Journal of Exercise Science

International Journal of Exercise Science 15(3): 1444-1456, 2022. Phase angle (PhA) is an index of cell membrane integrity and prognostic indicator of survival and quality of life in cancer survivors. The efficacy of exercise-based cancer rehabilitation programs (ExCR) on PhA is unknown. To assess the effect of ExCR on PhA in breast cancer survivors. Fifty-nine female breast cancer survivors (61 ± 9 years) were referred to the ExCR by their oncologist and participated in one-on-one exercise-based training for 90 minutes, 3 times a week, for 12 weeks. Training sessions included 45 minutes of resistance training at intensities between 40-85% of …

Functional Benefits Of Hard Martial Arts For Older Adults: A Scoping Review, Ian Miller, Mike Climstein, Luke Del Vecchio

International Journal of Exercise Science

International Journal of Exercise Science 15(3): 1430-1443, 2022. The present scoping review focused upon the functional benefits of hard martial arts training for older adults. The AXIS Critical Appraisal Tool was used to appraise all studies included in the review. A systematic literature search identified 265 papers via electronic database and ten papers from additional sources. Of these, six studies featuring 240 participants were included in the final scoping review. Of the included studies, three were randomized control trials and three were comparative studies with concurrent controls. The available studies outlined improvements in functional fitness parameters for older adults participating …

The Association Of Field Test Outcomes With Peak Oxygen Uptake In Patients With Cystic Fibrosis: A Systematic Review, Natália E. Campos, Fernanda M. Vendrusculo, Gisele A. Da Costa, Ingrid S. De Almeida, Nicolas A. Becker, Márcio V F Donadio

International Journal of Exercise Science

International Journal of Exercise Science 15(3): 1381-1394, 2022. The purpose of the study was to evaluate the association of field test outcomes with peak oxygen uptake (VO₂peak) in patients with cystic fibrosis (CF) and to describe the main prediction equations available. Data searches were performed in five databases (Pubmed, Embase, LILACs, Scopus and Web of Science) and also in the reference lists of articles included. The following inclusion criteria were used: studies including individuals with CF, presenting both a field test and a cardiopulmonary exercise testing (CPET), and describing a predictive equation or coefficient of correlation/determination. Case studies, …

Ua12/2/1 College Heights Herald: Kickin' It, Wku Student Affairs

WKU Administration Documents

Magazine edition of College Heights Herald, includes Adulting section.

• Moore, Jake. Here’s to a Mag-nificent Semester
• Turner, B & Debra Murray. Students, Alumni React to Loss of Folk Studies Graduate Program
• Crimmins, Michael. Faculty Leaders Concerned with Timothy Caboni’s Lack of Faculty Senate Attendance
• Trickett-Wile, Arthur. Cop a Pair - Melissa Bailey, Michael Jordan
• The Suspension of Humanities Programs Shouldn’t Come as a Shock
• Dock, Emma. Student Guide: Writing a Professional Email
• Johnson, Nicole. Bang for Your Buck: Party Edition
• Dock, Emma & Alyssa Butler. A Guide to Flying Alone
• Moore, Haden. How to Use Dark Humor
• Preparing for Grad …

Four Weeks Of Hericium Erinaceus Supplementation Does Not Impact Markers Of Metabolic Flexibility Or Cognition, Corey Grozier, Victor Alves, Lauren Killen, Eric O'Neal, Jeffrey Simpson, Hunter Waldman

International Journal of Exercise Science

International Journal of Exercise Science 15(2): 1366-1380, 2022. Hericium erinaceus (HE), also known as Lion’s Mane mushroom, has been found to enhance cognition and metabolic flexibility in various animal models. To date however, only four studies exist in humans and none have evaluated the effects of HE on markers of metabolic flexibility or cognitive performance. A single-blind, placebo controlled, parallel-longitudinal study was used to determine the effects of HE on markers of metabolic flexibility and cognition. Twenty-four participants completed a graded exercise test on a cycle ergometer to analyze substrate oxidation rates and markers of cardiorespiratory fitness. Additionally, two dual-task …