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The Effect Of Type Ii Diabetes Mellitus On Oxygen Uptake Kinetics During Heavy Exercise, Dustin R. Allen, Cory L. Butts, Davor Krnjajic, David Keller, Paul Mcdonough

International Journal of Exercise Science: Conference Proceedings

The kinetics of oxygen uptake (Vo₂) during the rest to exercise transition are thought to be modulated by intracellular metabolic processes. Diabetes has been shown to slow Vo₂ kinetics, likely due to the impact of diabetes upon microvascular oxygen exchange (Padilla et al, 2007). However, to date, recovery from exercise has yet to be studied in these patients. Thus, the purpose of this study was to test the hypothesis that the existence of diabetes would hamper Vo₂ kinetics during transitions to and from heavy leg cycling (H: Supra-LT). Nine subjects (4 control, 5 diabetic) completed three …

Deptor Expression Correlates With Muscle Protein Synthesis, Kevin L. Shimkus, Elyse V. Wudeck, Yasaman Shirazi-Fard, Mats I. Nilsson, Nicholas P. Greene, Harry A. Hogan, James D. Fluckey

International Journal of Exercise Science: Conference Proceedings

Mammalian target of rapamycin (mTOR) has long been declared a focal point of muscle protein synthesis. mTORC1 (an mTOR complex consisting of mTOR, raptor, PRAS40, and mLST8) has been associated with regulation of protein translation in muscle, altering expression and activity levels of key downstream targets S6K1 and eIF-4E-BP1. mTORC1 has been shown to be affected by various stimuli, including nutritional status, growth factors, and mechanical loading. But in past incidents we have found disconnects in muscle protein synthesis and mTOR signaling, stimulating discussions that mTOR content and activation alone may not be able to fully account for muscle protein …

The Development Of A Diabetes Intervention And Community Education Program, Rosanne Schrieber Keathley Ph.D., Judy R. Sandlin Ph.D., David Ficklen Md, Karen Bilsing Bs

International Journal of Exercise Science: Conference Proceedings

Title: DEVELOPMENT OF A DIABETES INTERVENTION AND COMMUNITY EDUCATION PROGRAM

Author(s): Rosanne Keathley, PHD1, Judy Sandlin, PHD2, David Ficklen, MD3, Karen Bilsing, BS4

Affiliations: 1Health and Kinesiology, Sam Houston State University, 2 Human Resource and Development, Texas A & M University, 3 Chief Medical Officer, Huntsville Memorial Hospital, 4 Community Relations Manager, Huntsville Memorial Hospital

Purpose: Currently 25.8 million people (8.3%) in the US are living with diabetes. This study assessed the need for a diabetes intervention program through community health screenings. Method: Participants (N=323) completed a diabetes risk questionnaire with health screenings. Ages ranged between 17 …