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Impact Of Intermittent Hypoxia On Glucose Tolerance In Type 2 Diabetes, Jiahui Zhao, Sten Stray-Gundersen, Sophie Lalande

International Journal of Exercise Science: Conference Proceedings

Hypoxia increases glucose uptake in skeletal muscle through an insulin-independent pathway. PURPOSE: To assess the impact of intermittent hypoxia on glucose and insulin concentrations during an oral glucose tolerance test in adults with type 2 diabetes. METHODS: Six adults with type 2 diabetes (5 men, age: 51±15 years, HbA1c: 7.3±1.5%) performed a 2-hour oral glucose tolerance test on two separate occasions. On both visits, venous blood samples were collected before and 30, 60, 90, and 120 min after the ingestion of a high-glucose drink. After ingestion of the drink, participants were exposed to either an intermittent hypoxia (IH) protocol, consisting …

Nutrition Able: A Lecture-Based Intervention To Promote Nutritional Literacy About Protein Intake In Women, Jeffery Bolte, Alejandra Garcia, Jacob Abalos, Jakson Johnson, Alex Joyce, Christopher Hinds, Jared Tuttle, Jeff Svec

International Journal of Exercise Science: Conference Proceedings

Sport performance is influenced by sport-specific requirements for body composition. One major predictor of body composition is protein intake. Higher protein intake tends to cause leaner body composition relative to lower protein intake, especially during caloric deficit. In Bexar County, ~72% of the adult population is overweight/obese and 15.5% are diabetic. This suggests that high protein diet could be a high leverage option in the San Antonio population for optimizing body composition for sport performance. Furthermore, late life sporting activity and protein intake is a primary method for mitigating sarcopenia, osteoporosis, fractures, and accidental death in post-menopausal women. PURPOSE: …

Thirty Minutes Of Electrical Muscle Stimulation Improves Glycemic Control, Jehu N. Apaflo, Irene John Tomy, Gabriel Narvaez, Joshua Labadah, Ulices Villalobos, Sudip Bajpeyi

International Journal of Exercise Science: Conference Proceedings

Electrical muscle stimulation is a suitable skeletal muscle contraction modality for people with physical functional disabilities and other sedentary individuals. While the extensive use of this technique has focused primarily on muscle strengthening and regeneration during rehabilitation, there is an increasing research interest to explore its potential to improve other metabolic health parameters similar to the benefits of conventional exercise. PURPOSE: This study aims to determine the effect of acute electrical stimulation on glycemic control in a predominantly Hispanic population. METHODS: Thirty-one participants (Males: 10; Females: 21; BMI: 33.3 ± 7.1 kg/m²; Age: 35.1 ± 12.0 …

Effects Of Neuromuscular Electrical Stimulation On Glycemic Control In A Hyperglycemic Population, Irene John Tomy, Jehu Apaflo, Victoria Rocha, Gabriel Narvaez, Joshua Labadah, Ulices Villalobos, Sudip Bajpeyi

International Journal of Exercise Science: Conference Proceedings

Hyperglycemia in people with prediabetes and diabetes, if left untreated, can cause serious health conditions and may lead to a diabetic coma. Muscle contraction through conventional exercise is known to increase glucose uptake in cells, thereby decreasing blood glucose levels. Neuromuscular electrical stimulation (NMES) is an innovative approach to contract skeletal muscle involuntarily. Whereas exercise is widely recommended for hyperglycemia management, it is not known whether NMES can be used as an alternative strategy to improve glycemic control. PURPOSE: The purpose of this study was to determine if the use of NMES for muscle contraction can improve glycemic control …

Physical Activity Assessment Of People With Type Ii Diabetes In The Dominican Republic, Camille H. Palarpalar, Kristen Green, Mónica Ortiz Rossi, Alex Rothstein, Lillian B. Niwagaba, Amerigo Rossi

International Journal of Exercise Science: Conference Proceedings

The prevalence of type II diabetes has increased nearly 25% in the past 10 years, leading to significantly higher risk of morbidity and premature mortality. Although it is well-known that physical activity (PA) improves diabetes outcomes, little is known about PA among Dominicans. PURPOSE: To evaluate PA participation and perceptions among people with type II diabetes in the Dominican Republic (DR). METHODS: Participants (N=29) were recruited from an urban diabetes clinic in Nagua, DR. Age, height, and weight were self-reported. Actigraph wGT3X-BT triaxial accelerometers were fitted for wear on the non-dominant wrist, and participants were instructed not to change their …

Postprandial And Fasting Lipopolysaccharide Levels In Healthy Hispanic Residents Of Southeast Texas With Positive Family History Of Type 2 Diabetes, Amanda J. Wheeler, Yu Lun Tai, Smaran Marupudi, Ryan D. Russell

International Journal of Exercise Science: Conference Proceedings

PURPOSE: Healthy people with a family history (FH+) of type 2 diabetes (T2D) display impaired metabolic and microvascular function prior to glucose intolerance, and are at greater risk for developing T2D. While mechanisms to explain this disparity are lacking, it is possible that intestinal permeability plays a role, as it is also linked with insulin resistance, glucose intolerance, and chronic inflammation. Lipopolysaccharides (LPS) act as an outer membrane component of gram-negative bacteria in intestines and play a role in inflammation and chronic disease when in circulation, thus serving as a surrogate measure of intestinal permeability. However, the link between FH+ …

Biphasic Glucose Curve Morphology Reflects Better Glucose Tolerance And Substrate Utilization, Jehu Narh Apaflo, Joshua Labadah, Ali Mossayebi, Victoria Rocha, Sudip Bajpeyi

International Journal of Exercise Science: Conference Proceedings

The shape of glucose curve during an oral glucose tolerance test is a plausible risk factor for insulin resistance and other metabolic disorders and could be a potential biomarker for predicting risk for developing diabetes. PURPOSE: This study aimed to compare the glucose tolerance and substrate utilization between monophasic and biphasic glucose curve morphologies. METHODS: A total of 50 subjects (33/17 male/female; Age: 27 ± 7.74 years; BMI: 27.7 ± 4.97 kg/m²) without diabetes were tested for a two-hour oral glucose tolerance after ingesting 75g of glucose drink. Blood glucose levels were measured at time points …

Lifestyle Factors Affecting Android Fat In Hispanic Residents Of The Rgv, Alexandro Rodriguez, Ryan D. Russell, Smaran Marupudi, Gabriel Figueroa, Jaime Rodriguez, Saraswathy Nair, Jimmy Gonzalez, Yu Lun Tai

International Journal of Exercise Science: Conference Proceedings

ABSTRACT

Approximately 79% of the Hispanic population in the Rio Grande Valley (HPRGV) are overweight or obese. As such, this population also have ~3x the type 2 diabetes (T2D) rates than the US average. Distribution of adipose tissue, affected largely by genetics and lifestyle (diet and physical activity, has been identified as a key-marker for T2D risk among apparently healthy individuals. However, the relationship of lifestyle factors such as diet and physical activity on android fat in healthy young Hispanics of the RGV has not been completely explored. Purpose: The purpose of this study was to determine whether there is …

Metabolic Flexibility In Healthy Hispanics In The Rio Grande Valley With And Without A Family History Of Type 2 Diabetes, Jaime Rodriguez, Ryan D. Russell, Gabriel A. Figueroa, Alexandro Rodriguez, Smaran Marupudi, Yu Lun Tai, Sara Swathy, Jimmy Gonzales

International Journal of Exercise Science: Conference Proceedings

ABSTRACT Type 2 Diabetes (T2D) has several comorbidities such as cardiovascular disease, elevated lipid profile, microvascular complications, and impaired metabolic flexibility (MF: the ability to switch substrate use upon stimulation). Further, healthy Caucasians with a family history of T2D (FH+) have impaired MF similar to T2D, suggesting impaired MF could be an early-detection tool to identify at-risk populations. Hispanics of the Rio Grande Valley have ~3x the T2D rates as the US average, and have ~79% of the people in this region are either overweight or obese. However, patterns of MF in this population have not been addressed. Purpose: The …

Impact Of Intermittent Hypoxia On The Glycemic Response To An Oral Glucose Tolerance Test, Sahar D. Massoudian, Frank Wojan, Jiahui Zhao, Sophie Lalande

International Journal of Exercise Science: Conference Proceedings

Hypoxia triggers glucose uptake independently from the action of insulin. PURPOSE: To determine the acute effect of intermittent hypoxia, defined as alternating short bouts of breathing hypoxic and room air, on plasma glucose levels during an oral glucose tolerance test in healthy individuals. We hypothesized that exposure to intermittent hypoxia would attenuate the increase in glucose levels in response to an oral glucose tolerance test. METHODS: Nine individuals (5 men, age: 24 ± 4 years, height: 175 ± 9 cm, weight: 71.0 ± 13.5 kg, HbA1c: 5.4 ± 0.1%) participated in the study. Participants visited the laboratory on two occasions. …

Sleep And Risk For Metabolic Syndrome, Hypertension, Diabetes And Obesity Among Community-Dwelling Older Adults, Philip Zendels, Trudy L. Moore-Harrison, Jane F. Gaultney

International Journal of Exercise Science

International Journal of Exercise Science 15(3): 88-102, 2022. Older adults often face a variety of health problems that are found less frequently in younger populations. Metabolic syndrome and other related diseases are common due to a variety of age and lifestyle factors. Sleep, often operationalized only as duration, quality, or apnea diagnosis, is associated with worse health outcomes across the lifespan. However, sleep is multi-faceted and may require a collection of measures in order to reflect this. This study examined a suite of self-reported sleep habits (risk for sleep apnea, night time duration, nap duration, quality, timing, and consistency of …

A Comparison Of High-Intensity Interval And Moderate Intensity Continuous Training On Glucose Regulation In Sedentary, Obese Individuals, Sophia R. Mirth, Brandon J. Sawyer, Dharini M. Bhammer, Glenn A. Gaesser

International Journal of Exercise Science: Conference Proceedings

It is well known that exercise is beneficial in the prevention of type 2 diabetes (T2D) but the ideal type of training is not clear. PURPOSE: To compare the effects of high-intensity interval training (HIIT) and moderate-intensity continuous training (MICT) on blood glucose regulation in sedentary, obese adults. METHODS: 22 sedentary, obese individuals were randomized into either HIIT or MICT. Each group exercised on a cycle ergometer 3 times/wk for 8 wks. The HIIT group performed 10, 1 min intervals at 90-95% HR_max with 1 min rest intervals in between. The MICT group performed 30 min of …

The Effects Of A Faith-Based Diabetes Program For African Americans, Pandora Goode

International Journal of Faith Community Nursing

Purpose: The purpose of the study was to pilot test the effectiveness of a diabetes self-management program for African Americans with Type 2 Diabetes (T2D) in a group format in a faith-based setting. The rationale for the study was to create appropriate diabetes education in response to the growing diabetes prevalence among African Americans. The investigator hypothesized that after completing a 12-week program, participants would have improved diabetes knowledge, self-management practices, hemoglobin A1C, and an increase in self-efficacy. By reaching these goals, this program would contribute to one of the Healthy People 2020 objectives of increasing the proportion of …

Role Of Acute And Chronic Glycemic Control On Covid-19 Severity And Length Of Hospital Stay In Hospitalized Patients, Ali Mossayebi, Helen Kreit, Sundar Cherukuri, Roshni A. Mandania, Jeannie B. Concha, Hyejin Jung, Amy Wagler, Akshay Gupte, Abhizith Deoker, Sudip Bajpeyi

International Journal of Exercise Science: Conference Proceedings

COVID-19 patients with diabetes have greater morbidity and mortality. Glycated hemoglobin (A1c) indicates chronic glycemic control and is considered a standard of care in the diagnosis and management of diabetes. Whereas, fasting blood glucose (FBG) indicates acute glycemic control and is also recommended option to diagnose diabetes. PURPOSE: The purpose of this study was to determine the effects of acute and chronic glycemic control on severity and length of hospital stay among hospitalized patients with COVID-19. METHODS: This retrospective study used medical records from patients admitted to the University Medical Center, El Paso, TX with COVID-19 (n=364; age …

Detection Of P2x3 In Drg Using An Automated Approach To Immunoblotting, Jess, Junghoon Lee, Audrey J. Stone, Michelle L. Harrison

International Journal of Exercise Science: Conference Proceedings

Exaggerated cardiovascular (CV) responses to exercise can lead to adverse CV events. Previous studies have reported that P2X₃ receptors, found on the peripheral endings of afferents, contribute to an exaggerated exercise pressor reflex in individuals with CV-related diseases. One way to investigate the role played by these receptors in CV pathophysiology is through immunoblotting. The Jess (Protein Simple) provides an automated option for the protein separation and immunoblotting of the traditional Western Blot and allows for total protein staining, an improvement over the use of loading controls to normalize for sample loading variability. PURPOSE: The purpose of this study …

The Effect Of Acute And Chronic Thermotherapy On Type 2 Diabetic Skeletal Muscle Cell Viability And Gene Expression: Pilot Study, Louay Bachnak, Jean Sparks, Xavier F. Gonzales, Daniel Newmire, Felix Omoruyi

International Journal of Exercise Science: Conference Proceedings

Diabetes is a chronic metabolic disease affecting millions of people globally. Type 2 diabetes is associated with insulin resistance or a defective secretion of insulin from the pancreas. The skeletal muscle system accounts for 80% of glucose uptake and is a vital player in healthy aging and muscle mass maintenance. PURPOSE: The purpose of this study was to investigate the effects of thermotherapy on gene expression and cell viability in Type 2 Diabetic skeletal muscle. METHODS: Human skeletal muscle myoblast (HSMM) and Diabetic Type 2 human skeletal muscle myoblast (D-HSMM) (Lonza Inc, Walkersville, MD) were cultured until 90% confluency was, …

Plasma Lipid, Glucose, And Immune Responses To Consumption Of Nutritive And Nonnutritive Sweeteners And Exercise, Jarrett Walbolt, Yunsuk Koh

International Journal of Exercise Science: Conference Proceedings

Although nonnutritive sweeteners are widely used as substitutes for nutritive sweeteners, it is currently uncertain how these commonly available sweeteners affect plasma glucose and lipid metabolism. PURPOSE: To examine how nutritive and nonnutritive sweeteners influence plasma lipid profiles, complete blood counts, and plasma glucose content at rest and during exercise. METHODS: This randomized, double-blinded, cross-over design study included 9 healthy, college aged, individuals (4 females and 5 males). In four separate visits, participants consumed 8 oz of sweetened drink in random order with either 445mg of stevia, 507mg of aspartame, 169mg of sucralose, or 110,000mg of sucrose mixed into water. …

Mathematical Modeling Of Diabetic Foot Ulcers Using Optimal Design And Mixed-Modeling Techniques, Michael Belcher

Mahurin Honors College Capstone Experience/Thesis Projects

A mathematical model for the healing response of diabetic foot ulcers was developed using averaged data (Krishna et al., 2015). The model contains four major factors in the healing of wounds using four separate differential equations with 12 parameters. The four differential equations describe the interactions between matrix metalloproteinases (MMP-1), tissue inhibitors of matrix metalloproteinases (TIMP-1), the extracellular matrix (ECM) of the skin, and the fibroblasts, which produce these proteins. Recently, our research group obtained the individual patient data that comprised the averaged data. The research group has since taken several approaches to analyze the model with the individual …

Investigating The Change In The Out-Of-Pocket Cost Of Insulin Over Time, Jared Long

Mahurin Honors College Capstone Experience/Thesis Projects

Insulin is often cited as a classic near perfectly inelastic good; for those living with Type-1 diabetes, antihyperglycemic medicines are the only thing standing between them and possible death, and they must be willing to pay for the medication regardless of the price. When researchers at the University of Toronto released the patent for insulin in 1922, they asked for only $1 so that the medication would be available to as many people as possible; however, as insulin analogs and new biosimilar substitutes have been invented, the price of medications has increased substantially. While the rising cost of insulin has …

Exploring Health Related Lifestyle Habits And Influences In Rural India, Priyanka Aranha

International Journal of Exercise Science: Conference Proceedings

Background: According to the World Health Organization (WHO) diabetes in India is projected to increase from 31.7 million in 2000 to 79.4 million in 2030. This drastic growth clearly outlines the need for an increase in both awareness and education. Purpose: The purpose of this project was to collaborate with the non-governmental organization, Mysore Resettlement and Development Agency (MYRADA), to develop an understanding of the perspective towards diabetes in the Chitradurga District. Methods: Focus groups were developed within eight villages to discuss lifestyle behaviors (i.e. level of physical activity, leisure time, occupation, nutritional habits, alcohol and tobacco …

Repeated Plyometric Exercise Attenuates Blood Glucose In Healthy Adults, Saldiam R. Barillas, Casey M. Watkins, Megan A. Wong, Ian J. Dobbs, David C. Archer, Cameron N. Munger, Andrew J. Galpin, Jared W. Coburn, Lee E. Brown

International Journal of Exercise Science

International Journal of Exercise Science 10(7): 1076-1084, 2017. Plyometric exercise is popular in commercial exercise programs aiming to maximize energy expenditure for weight loss. However, the effect of plyometric exercise on blood glucose is unknown. The purpose of this study was to investigate the effect of relatively high intensity plyometric exercise on blood glucose. Thirteen subjects (6 females age= 21.8 ± 1.0 yrs.; height= 163.7 ± 7.8 cm; mass= 60.8 ± 6.7 kg and 7 males age= 22.0 ± 2.6 yrs.; height= 182.3 ± 3.6 cm; mass= 87.4 ± 12.5 kg) volunteered to participate. Subjects completed two random conditions on …

The Effect Of Acute Hyperglycemia On Muscular Strength, Power And Endurance, Franklin Lime-Ma, Joshua A. Cotter, Evan E. Schick

International Journal of Exercise Science

International Journal of Exercise Science 10(3): 390-396, 2017. The purpose of this study was to elucidate the impact of acute hyperglycemia on skeletal muscle strength, power, and endurance. Ten male collegiate athletes (age 21.5 ± 1.5 years, height 186 ± 2.03 cm, body mass 108.8 ± 7.6 kg) participated in 2 testing sessions, separated by 7 days and randomized for either high glucose (HG) or control (C) treatment conditions. HG consumed a high glucose drink (2 g glucose/kg body weight) while controls consumed an isocaloric nutrition bar (40% protein, 30% fat, and 30% carbohydrate). Blood glucose (BC) levels for HG …

High Fat Diet Induced Obesity Impairs Skeletal Muscle Glycogen And Lipid Preservation After Adiponectin Incubation, Cesar Meza, Cynthia Montenegro, Catalina De La Peña, Lannie O'Keefe, Shaan Naughton, Anna Simcocks, Deanne Hryciw, Michael Mathai, Andrew Mcainch, Sudip Bajpeyi

International Journal of Exercise Science: Conference Proceedings

High fat diets have been attributed as critical factors contributing to obesity and type 2 diabetes, characterized by increased lipid accumulation, impaired glucose uptake, and defects in glycogen storage in skeletal muscle. Adiponectin, an adipokine, has been shown to have antidiabetic effects by improving fat oxidation and glucose uptake. PURPOSE: To investigate the effects of adiponectin incubation, in high fat diet induced obese rats, on measures of skeletal muscle substrate metabolism including glycogen, glucose transporter 4 (GLUT4), lipid, and mitochondrial contents. METHODS: Male Sprague Dawley rats were fed a Western-style (21% fat by weight; 41% total energy) high …

Muscle Mir-27a Is Decreased During Diabetes And Is Regulated By Calcineurin Signaling, E. Muñoz, A. Folk, J. Rahnert, X. Wang, S. Price, J. Jeka, J. Park, M. Hudson

International Journal of Exercise Science: Conference Proceedings

Please refer to the pdf version of the abstract located adjacent to the title.

Passive Hyperthermia Therapy Similarly Reduces Arterial Blood Pressure In Obese Type 2 Diabetic And Healthy Individuals, Eric Rivas

International Journal of Exercise Science: Conference Proceedings

Diabetes which is associated with impaired glycemic control, can damage macro and microvasculature, and impair vascular relaxation (i.e., endothelial dysfunction). The high thermal conductance of hot water will cause thermoregulatory adjustments that increase cardiac output, heart rate and stroke volume while reducing central venous pressure. This project tested the hypothesis that an acute bout of hot water hyperthermia will reduce arterial blood pressure during and following the exposure, but the response will be attenuated in obese type 2 diabetics. Eleven obese type 2 diabetics (T2D) (50.1 ± 12 y, 45 ± 7.1% fat mass, 7.5 ± 1.8% HbA1C) and nine …

Pre-Prandial Vinegar Ingestion Improves Two-Hour Glucose Control In Older, Type Ii Diabetics More Than Post-Prandial Walking, Sarah J. Taylor, Matthew J. Garver, Anna E. Ciufo, Taylor G. Flowers, Chase M. Harbach, Austin A. Ray, Cory M. Scheadler

International Journal of Exercise Science: Conference Proceedings

Background: Exercise engagement benefits diabetic patients through an insulin-like effect on muscle. Literature indicates that vinegar consumption may lower blood glucose levels. It is not currently clarified whether a relative amount of vinegar ingestion or a walking bout is more effective at controlling glucose in older, Type II diabetics during the acute phase following a meal. Purpose: The aim was to directly compare the impact of preferred-pace walking (15 min, postprandial) versus ingestion of a relative quantity of vinegar (0.3 g/kg) on two-hour glucose control. Methods: The two arms of the trial were completed in a randomized, …

C.Elegans As A Diabetes & Ischemia Model: Identification Of Genetic And Cellular Changes That Modulate The Survival Of Hyperglycemia And Oxygen-Deprivation, Anastacia M. Garcia, Mary L. Ladage, Brian K. Mcfarlin, Rajeev K. Azad, Pamela A. Padilla

International Journal of Exercise Science: Conference Proceedings

Diet represents an exogenous influence that often yields colossal effects on an individual’s phenotype, physiology, long-term health and disease risk. The overconsumption of dietary sugars for example, has contributed to significant increases in obesity and type 2 diabetes, health issues that are costly both in terms of dollars and human life. Additionally, individuals with these conditions have compromised oxygen delivery and thus, an increased vulnerability to other oxygen-deprivation related disease states, including cardiovascular disease, ischemic strokes, vascular and coronary diseases and myocardial infarction. While human and other mammalian studies have shown that individuals with type 2 diabetes have a worse …

The Truth About Type 1 Diabetes Mellitus: The Myths Exposed, Caitlynn Oberhausen

Mahurin Honors College Capstone Experience/Thesis Projects

Children with type 1 diabetes, T1DM, live with a widely misunderstood, chronic disease. The daily management regimens and psychosocial aspect of T1DM bring attention to the child with diabetes. Myths and misconceptions of diabetes management abound. The intent of this research is to address myths and misconceptions by reading a children’s book, written and illustrated by the researcher, to students in grades 3-5 at a local elementary school and measuring change in knowledge with an assessment tool based on book content.

Comparing Effectiveness Of Motivational Signage For Promoting Physical Activity Between Two Difference Story Buildings, Junyoung Hong

International Journal of Exercise Science: Conference Proceedings

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Can Follow Up Phone Calls Decrease Complications Of Chemotherapy Toxicities In Adults?, Maire M. Blankenship

Doctor of Nursing Practice Technical Reports

Approximately 22% of all cancer patients in the United States receive chemotherapy. Older adults account for 60 % of new cancer diagnoses in the United States. The aging process is associated with comorbidities that potentially can increase toxicities associated with chemotherapy. These include coronary artery disease, hypertension, and diabetes. Monitoring for toxicities during treatment and intervening when needed allows patients to move forward in their treatment plan. Interruptions in the treatment plan have the potential to adversely affect treatment goals. The purpose of this study is to determine if patients receiving phone calls on predetermined days had fewer days of …