Problem-Based Learning And Information Literacy: Revising A Technical Writing Class, Kelly Diamond

Faculty & Staff Scholarship

This chapter discusses the collaboration between a librarian and faculty member to revise an online technical writing course using the Association of College and Research Libraries (ACRL) Framework for Information Literacy, problem-based learning, and instructional design principles. The chapter outlines three components of course revision: 1) re-design online course to be more engaging to students as well as easier to navigate; 2) create assignments and activities to mirror actual workplace writing tasks; 3) develop research assignments focused on information literacy skills used in the workplace. Using elements from ADDIE (Analyze; Design; Develop; Implement; Evaluate) and Backward Design, the course …

Intranasal Peptide-Based Fpva-Klh Conjugate Vaccine Protects Mice From Pseudomonas Aeruginosa Acute Murine Pneumonia, Emel Sen-Kilic, Catherine B. Blackwood, Dylan T. Boehm, Wiliam T. Witt, Aaron C. Malkowski, Justin R. Bevere, Ting Y. Wong, Jesse M. Hall, Shelby D. Bradford, Melinda E. Varney, Fredrick Heath Damron, Mariette Barbier

Faculty & Staff Scholarship

Pseudomonas aeruginosa is an opportunistic pathogen causing acute and chronic respiratory infections associated with morbidity and mortality, especially in patients with cystic fibrosis. Vaccination against P. aeruginosa before colonization may be a solution against these infections and improve the quality of life of at-risk patients. To develop a vaccine against P. aeruginosa, we formulated a novel peptide-based P. aeruginosa subunit vaccine based on the extracellular regions of one of its major siderophore receptors, FpvA. We evaluated the effectiveness and immunogenicity of the FpvA peptides conjugated to keyhole limpet hemocyanin (KLH) with the adjuvant curdlan in a murine vaccination and challenge …

Mutations In Arl2bp, A Protein Required For Ciliary Microtubule Structure, Cause Syndromic Male Infertility In Humans And Mice, Abigal R. Moye, Nicola Bedoni, Jessica G. Cunningham, Urikhan Sanzhaeva, Eric S. Tucker, Peter Mathers, Virginie G. Peter, Mathieu Quinodoz, Liliana P. Paris, Luisa Coutinho-Santos, Pedro Camacho, Madeleine G. Purcell, Abbie C. Winkelmann, James A. Foster, Elena N. Pugacheva, Carlo Rivolta, Visvanathan Ramamurthy

Faculty & Staff Scholarship

Cilia are evolutionarily conserved hair-like structures with a wide spectrum of key biological roles, and their dysfunction has been linked to a growing class of genetic disorders, known collectively as ciliopathies. Many strides have been made towards deciphering the molecular causes for these diseases, which have in turn expanded the understanding of cilia and their functional roles. One recently-identified ciliary gene is ARL2BP, encoding the ADP-Ribosylation Factor Like 2 Binding Protein. In this study, we have identified multiple ciliopathy phenotypes associated with mutations in ARL2BP in human patients and in a mouse knockout model. Our research demonstrates that spermiogenesis …

Educational Intervention Improves Fruit And Vegetable Intake In Young Adults With Metabolic Syndrome Components, Rashel L. Clark, Oluremi A. Famodu, Ida Holásková, Aniello M. Infante, Pamela J. Murray, I. Mark Olfert, Joseeph W. Mcfadden, Marianne T. Downes, Paul D. Chantler, Matthew W. Duespohl, Christopher F. Cuff, Melissa D. Olfert

Faculty & Staff Scholarship

The FRUVEDomics study investigates the effect of a diet intervention focused on increasing fruit and vegetable intake on the gut microbiome and cardiovascular health of young adults with/at risk for metabolic syndrome(MetS). It was hypothesized that the recommended diet would result in metabolic and gut microbiome changes. The 9-week dietary intervention adhered to the US Department of Agriculture Dietary Guidelines for Americansand focused on increasing fruit and vegetable intake to equal half of the diet. Seventeen eligible young adults with/or at high risk of MetS consented and completed preintervention and postintervention measurements, including anthropometric, body composition, cardiovascular, …

Investigational Monoclonal Antibodies In The Treatment Of Multiple Myeloma: A Systematic Review Of Agents Under Clinical Development, Ahmad Iftikhar, Hamza Hassan, Nimra Iftikhar, Adeela Mushtaq, Atif Sohail, Nathaniel Rosko, Rajshekhar Chakraborty, Faryal Razzaq, Sonia Sandeep, Jason Neil Valent, Abraham Sebastian Kanate, Faiz Anwer

Faculty & Staff Scholarship

Background: Immunotherapy for multiple myeloma (MM) has been the focus in recent years due to its myeloma-specific immune responses. We reviewed the literature on non-Food and Drug Administration (FDA) approved monoclonal antibodies (mAbs) to highlight future perspectives. We searched PubMed, EMBASE, Web of Science, Cochrane Library and ClinicalTrials.gov to include phase I/II clinical trials. Data from 39 studies (1906 patients) were included. Of all the agents, Isatuximab (Isa, anti-CD38) and F50067 (anti-CXCR4) were the only mAbs to produce encouraging results as monotherapy with overall response rates (ORRs) of 66.7% and 32% respectively. Isa showed activity when used in combination with …

Analyses And Prevention Of Coal Spontaneous Combustion Risk In Gobs Of Coal Mine During Withdrawal Period, Wan-Xing Ren, Qing Guo, Hui-Hui Yang

Faculty & Staff Scholarship

Coal spontaneous combustion (CSC) in gob causes notorious safety issues to workers, especially during withdrawal period. Withdrawal period was normally divided into three stages (initial stage, expanding back channel stage and equipment returning stage) when evaluating and preventing the risk of CSC. This study first analyzed the characteristics of ventilation system at each stage, such as oxidized zone movement, local fire wind pressure and air leakage. Then, principles and specialized measurements were applied to minimize the ranges and effects of CSC in gob. In detail, this includes reducing the total air volume flow of mining face in initial stage, adding …

Underground Ground Control Monitoring And Interpretation, And Numerical Modeling, And Shield Capacity Design, Syd S. Peng, Jingyi Cheng, Feng Du, Yuting Xue

Faculty & Staff Scholarship

Mine or longwall panel layout is a 3D structure with highly non-uniform stress distribution. Recognition of such fact will facilitate underground problem identification/investigation and solving by numerical modeling through proper model construction. Due to its versatility, numerical modeling is the most popular method for ground control design and problem solving. However numerical modeling results require highly experienced professionals to interpret its validity/applicability to actual mining operations due to complicated mining and geological conditions. Underground ground control monitoring is routinely performed to predict roof behavior such as weighting and weighting interval without matching observation of face mining condition while the …

Bariatric Surgery Outcomes In Appalachia Influenced By Surgery Type, Diabetes, And Depression, Makenzie L. Barr, Lawrence E. Tabone, Stephanie J. Cox, Cassie Brode, Nova Szoka, I. Mark Olfert, Laura Davisson, Melissa D. Olfert

Faculty & Staff Scholarship

Background

Most effective treatment for morbid obesity and its comorbidities is bariatric surgery. However, research is limited on weight loss and associated outcomes among patients in Appalachia. The objective of this study was to examine demographic and comorbidity influence on surgical outcomes of this population including age, sex, race, state of residence, education, marital status, body mass index (BMI kg/m2), excess body weight (EBW), percent excess weight loss (%EWL), blood pressure, diagnosed depression, diagnosed type 2 diabetes (T2D), Beck Depression Inventory-II (BDI-II), and laboratory values (i.e., hemoglobin A1c).

Methods

A retrospective electronic medical record (EMR) data extraction was performed on …

Differences Between Occupational And Non-Occupational-Related Motor Vehicle Collisions In West Virginia: A Cross-Sectional And Spatial Analysis, Toni Marie Rudisill

Faculty & Staff Scholarship

Background

Motor vehicle collisions comprise the majority of occupational-related fatalities in the United States and West Virginia has one of the highest occupational-related fatality rates in the nation. The purpose of this study was to compare work and non-work-related collisions, crash locations, and the characteristics of in-state and out-of-state drivers ≥18 years of age who were fatally injured in work-related collisions in West Virginia.

Methodology

Data were from the 2000–2017 Fatality Analysis Reporting System. Work and non-work-related crashes and characteristics in-state vs. out-of-state drivers were compared using binary and multivariable logistic regression analyses. Crash locations were compared via spatial analyses …

Effect Of A Motivational Interviewing–Based Intervention On Initiation Of Mental Health Treatment And Mental Health After An Emergency Department Visit Among Suicidal Adolescents, Jacqueline Grupp-Phelan, Jack Stevens, Stephanie Boyd, Daniel M. Cohen, Robert T. Ammerman, Stacey Liddy-Hicks, Kendra Heck, Steven C. Marcus, Lara Stone, John V. Campo, Jefferey A. Bridge

Faculty & Staff Scholarship

Abstract

IMPORTANCE Emergency department (ED) visits present opportunities to identify and refer suicidal youth for outpatient mental health care, although this practice is not routine.

OBJECTIVE To examine whether a motivational interviewing–based intervention increases linkage of adolescents to outpatient mental health services and reduces depression symptoms and suicidal ideation in adolescents seeking emergency care for non–mental health–related concerns who screen positive for suicide risk.

DESIGN, SETTING, AND PARTICIPANTS In this randomized clinical trial, adolescents aged 12 to 17 years who screened positive on the Ask Suicide Screening Questions (ASQ) during a nonpsychiatric ED visit at 2 academic pediatric EDs in …

Acute Levodopa Dosing Around-The-Clock Ameliorates Rem Sleep Without Atonia In Hemiparkinsonian Rats, Vishakh Iyer, Quynh Vo, Anthony Mell, Siven Chinniah, Ashley Zenerovitz, Kala Venkiteswaran, Allen R. Kunselman, Jidong Fang, Thyagarajan Subramanian

Faculty & Staff Scholarship

• Article
• Open Access
• Published: 29 November 2019

Acute levodopa dosing around-the-clock ameliorates REM sleep without atonia in hemiparkinsonian rats

• Vishakh Iyer,
• Quynh Vo,
• Anthony Mell,
• Siven Chinniah,
• Ashley Zenerovitz,
• Kala Venkiteswaran,
• Allen R. Kunselman,
• Jidong Fang &
• Thyagarajan Subramanian

npj Parkinson's Disease volume 5, Article number: 27 (2019) Cite this article

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Abstract

Rapid-eye-movement (REM) sleep without atonia (RSWA), a marker of REM sleep behavior disorder (RBD), is frequently comorbid with Parkinson’s disease (PD). Although rodent models are commonly used for studying PD, the neurobiological and behavioral correlates of …

Surgical Correction Of Aortic Regurgitation Using A Haart 300™ Rigid Aortic Ring: A Novel Method To Standardize Aortic Valve Repair, Radoslaw Gocol, Marek Jasiński, Damian Hudziak, Jaroslaw Bis, Aleksandra Żak, Piotr Duraj, Magdalena Mizia, J. Scott Rankin, Marek A. Deja

Faculty & Staff Scholarship

No abstract provided.

Exercise And Adiposity In Overweight And Obese Children And Adolescents: A Systematic Review With Network Meta-Analysis Of Randomised Trials, George A. Kelley, Kristi S. Kelley, Russell R. Pate

Faculty & Staff Scholarship

Objectives Determine both the effects and hierarchy of effectiveness for exercise interventions (aerobic, strength training or both) on selected measures of adiposity (body mass index (BMI) in kg/m2 , fat mass and per cent body fat) in overweight and obese children and adolescents. Design Network meta-analysis of randomised exercise intervention trials. Setting Any setting where a randomised trial could be conducted. Participants Overweight and obese male and/or female children and adolescents 2–18 years of age. Interventions Randomised exercise intervention trials>4 weeks, published between 1 January 1973 and 22 August 2018, and which included direct and/or indirect evidence for aerobic, …

Impact Of Ethanol Plant Location On Corn Revenues For U.S. Farmers, Ani L. Katchova, Ana Claudia Sant'anna

Faculty & Staff Scholarship

settings Open AccessArticle

Impact of Ethanol Plant Location on Corn Revenues for U.S. Farmers

by Ani L. Katchova 1,* andAna Claudia Sant’Anna 2 1 Department of Agricultural, Environmental, and Development Economics, The Ohio State University, Columbus, OH 43210, USA 2 Division of Resource Economics and Management, West Virginia University, Morgantown, WV 26506, USA * Author to whom correspondence should be addressed. Sustainability 2019, 11(22), 6512; https://doi.org/10.3390/su11226512 Received: 22 October 2019 / Revised: 11 November 2019 / Accepted: 15 November 2019 / Published: 19 November 2019 (This article belongs to the Special Issue Green, Closed Loop, Circular Bio-Economy) …

Cannabis And Psychosis Through The Lens Of Dsm-5, Nathan T. Pearson, James H. Berry

Faculty & Staff Scholarship

Evidence for an association between cannabis and psychosis has been documented in literature in many forms including experimental studies, epidemiological data, and case series. The association has implications for psychotic outcomes ranging from mild to severe and occurring over minutes to years. Due to the huge variety of exposures and outcome measures reported, creating a coherent account of all the available information is difficult. A useful way to conceptualize these wide-ranging results is to consider the association between cannabis and psychosis as it occurs within the context of widely used DSM-5 diagnoses. In the present review we examine cannabis/psychosis associations …

Comparison Of Whole-Genome Sequences Of Legionella Pneumophila In Tap Water And In Clinical Strains, Flint, Michigan, Usa, 2016, Emily Garner, Connor L. Brown, David Otto Schwake, William J. Rhoads, Gustavo Aragon-Argoty, Liqing Zhang, Guillaume Jospin, David A. Coil, Jonathan A. Eisen, Marc A. Edwards, Amy Pruden

Faculty & Staff Scholarship

During the water crisis in Flint, Michigan, USA (2014–2015), 2 outbreaks of Legionnaires’ disease occurred in Genesee County, Michigan. We compared whole-genome sequences of 10 clinical Legionella pneumophila isolates submitted to a laboratory in Genesee County during the second outbreak with 103 water isolates collected the following year. We documented a genetically diverse range of L. pneumophila strains across clinical and water isolates. Isolates belonging to 1 clade (3 clinical isolates, 3 water isolates from a Flint hospital, 1 water isolate from a Flint residence, and the reference Paris strain) had a high degree of similarity (2–1,062 single-nucleotide polymorphisms), all …

Mitsui-7,Heat-Treated, And Nitrogen-Doped Multi-Walled Carbon Nanotubes Elicit Genotoxicity In Human Lung Epithelial Cells, Katelyn J. Siegrist, Steven H. Reynolds, Dale W. Porter, Robert R. Mercer, Allison K. Bauer, David Lowry, Lorenzo Cena, Todd A. Stueckle, Michael L. Kashon, John Wiley, Jeffrey L. Salisbury, John Mastovich, Kristin Bunker, Mark Sparrow, Jason S. Lupoi, Aleksandr B. Stefaniak, Michael J. Keane, Shuji Tsuruoka, Mauricio Terrones, Michael Mccawley, Linda M. Sargent

Faculty & Staff Scholarship

The unique physicochemical properties of multi-walled carbon nanotubes (MWCNT) have led to many industrial applications. Due to their low density and small size, MWCNT are easily aerosolized in the workplace making respiratory exposures likely in workers. The International Agency for Research on Cancer designated the pristine Mitsui-7 MWCNT (MWCNT-7) as a Group 2B carcinogen, but there was insufficient data to classify all other MWCNT. Previously, MWCNT exposed to high temperature (MWCNT-HT) or synthesized with nitrogen (MWCNT-ND) have been found to elicit attenuated toxicity; however, their genotoxic and carcinogenic potential are not known. Our aim was to measure the genotoxicity of …

Finding New Cell Wall Regulatory Genes In Populus Trichocarpa Using Multiple Lines Of Evidence, Anna Furches, David Kainer, Deborah Weighill, Annabel Large, Piet Jones, Angelica M. Walker, Jonathon Romero, Joao Gabriel Felipe Machado Gazolla, Wayne Joubert, Manesh Shah, Jared Streich, Priya Ranjan, Jeremy Schmutz, Avinash Sreedasayam, David Macaya-Sanz, Nan Zhao, Madhavi Z. Martin, Xiaolan Rao, Richard A. Dixon, Stephen Difazio, Timothy J. Tschaplinski, Jin-Giu Chen, Gerald A. Tuskan, Daniel Jacobson

Faculty & Staff Scholarship

Understanding the regulatory network controlling cell wall biosynthesis is of great interest in Populus trichocarpa, both because of its status as a model woody perennial and its importance for lignocellulosic products. We searched for genes with putatively unknown roles in regulating cell wall biosynthesis using an extended network-based Lines of Evidence (LOE) pipeline to combine multiple omics data sets in P. trichocarpa, including gene coexpression, gene comethylation, population level pairwise SNP correlations, and two distinct SNP-metabolite Genome Wide Association Study (GWAS) layers. By incorporating validation, ranking, and filtering approaches we produced a list of nine high priority gene candidates for …

A Rare Case Of Adult Congenital Heart Disease: Single Ventricular Chamber With Anomalous Right Coronary Artery In An Octogenarian, Muhammad Shabbir Rawala, Anna Saleem Ahmed, Syed Bilal Rizvi

Faculty & Staff Scholarship

ABSTRACT Patients with single-ventricle physiology encompass a wide array of anatomic subtypes, including but not limited to: tricuspid atresia, hypoplastic left heart syndrome, doubleoutlet or double-inlet ventricles. The outcomes for patients with single ventricle born before 1990 are relatively poor. An 81-year-old female presented to the hospital as non-ST elevation myocardial infarction. She was started on antiplatelet and anticoagulation. Echocardiogram revealed a single ventricle which was thought to be left ventricle with possible transposition of great vessels. Angiography was performed that identified the single ventricle and anomalous origin of the right coronary artery (RCA). She was also found to have …

Gwtc-1: A Gravitational-Wave Transient Catalog Of Compact Binary Mergers Observed By Ligo And Virgo During The First And Second Observing Runs, B. P. Abbott

Faculty & Staff Scholarship

We present the results from three gravitational-wave searches for coalescing compact binaries with component masses above 1 M⊙ during the first and second observing runs of the advanced gravitationalwave detector network. During the first observing run (O1), from September 12, 2015 to January 19, 2016, gravitational waves from three binary black hole mergers were detected. The second observing run (O2), which ran from November 30, 2016 to August 25, 2017, saw the first detection of gravitational waves from a binary neutron star inspiral, in addition to the observation of gravitational waves from a total of seven binary black hole mergers, …

Local Synaptic Inputs Support Opposing, Network-Specific Odor Representations In A Widely Projecting Modulatory Neuron, Xiaonan Zhang, Kaylynn Coates, Andrew Dacks, Cengiz Günay, J. Scott Lauritzen, Feng Li, Steven A. Calle-Schuler, Davi Bock, Quentin Gaudry

Faculty & Staff Scholarship

Serotonin plays different roles across networks within the same sensory modality. Previously, we used whole-cell electrophysiology in Drosophila to show that serotonergic neurons innervating the first olfactory relay are inhibited by odorants (Zhang and Gaudry, 2016). Here we show that network-spanning serotonergic neurons segregate information about stimulus features, odor intensity and identity, by using opposing coding schemes in different olfactory neuropil. A pair of serotonergic neurons (the CSDns) innervate the antennal lobe and lateral horn, which are first and second order neuropils. CSDn processes in the antennal lobe are inhibited by odors in an identity independent manner. In the lateral …

Cardiac Prostheses‐Related Hemolytic Anemia, Mohamad Alkhouli, Ali Farooq, Ronald S. Go, Sudarshan Balla, Chalak Berzingi

Faculty & Staff Scholarship

Hemolysis is an unintended sequel of temporary or permanent intracardiac devices. However, limited data exist on the characteristics and treatment of hemolysis in patients with cardiac prostheses. This entity, albeit uncommon, often poses significant diagnostic and management challenges to the clinical cardiologist. In this article, we aim to provide a contemporary overview of the incidence, mechanisms, diagnosis, and management of cardiac prosthesis-related hemolysis.

Differences In Sodium Channel Densities In The Apical Dendrites Of Pyramidal Cells Of The Electrosensory Lateral Line Lobe, Sree I. Motipally, Kathryne M. Allen, Daniel K. Williamson, Gary Marsat

Faculty & Staff Scholarship

Heterogeneity of neural properties within a given neural class is ubiquitous in the nervous system and permits different sub-classes of neurons to specialize for specific purposes. This principle has been thoroughly investigated in the hindbrain of the weakly electric fish A. leptorhynchus in the primary electrosensory area, the Electrosensory Lateral Line lobe (ELL). The pyramidal cells (PCs) that receive inputs from tuberous electroreceptors are organized in three maps in distinct segments of the ELL. The properties of these cells vary greatly across maps due to differences in connectivity, receptor expression, and ion channel composition. These cells are a seminal example …

A Novel Cooperative Distributed Secondary Controller For Vsi And Pq Inverters Of Ac Microgrids, F. Doost Mohammadi, H. Keshtkar, A. Dehghan Banadaki, A. Feliachi

Faculty & Staff Scholarship

This paper proposes a novel cooperative secondary control strategy for microgrids which is fully distributed. There is a two-layered coordination, which exists between inverter based DGs of both types, i.e. Voltage Source Inverter (VSI) and Current Source Inverter (CSI), also called PQ inverter. In first layer of the proposed two-layered cooperative control strategy, VSIs will take care of the primary average voltage regulation by implementing the average consensus algorithm (ACA); then in the second layer of control, the PQ inverters will improve the voltage quality of the microgrid while maintaining the average voltage of buses at the same desired level. …

Application Of Mobile Health, Telemedicine And Artificial Intelligence To Echocardiography, Karthik Seetharam, Nobuyuki Kagiyama, Partho P. Sengupta

Faculty & Staff Scholarship

The intersection of global broadband technology and miniaturized high-capability computing devices has led to a revolution in the delivery of healthcare and the birth of telemedicine and mobile health (mHealth). Rapid advances in handheld imaging devices with other mHealth devices such as smartphone apps and wearable devices are making great strides in the field of cardiovascular imaging like never before. Although these technologies offer a bright promise in cardiovascular imaging, it is far from straightforward. The massive data influx from telemedicine and mHealth including cardiovascular imaging supersedes the existing capabilities of current healthcare system and statistical software. Artificial intelligence with …

Closed-Loop Cardiovascular Interactions And The Baroreflex Cardiac Arm: Modulations Over The 24 H And The Effect Of Hypertension, Gianfranco Parati, Paolo Castiglioni, Andrea Faini, Marco Di Rienzo, Giuseppe Mancia, Riccardo Barbieri, J. Philip Saul

Faculty & Staff Scholarship

Closed-loop models of the interactions between blood pressure (BP) and heart rate variations allow for estimation of baroreflex sensitivity (feedback effects of BP changes on heart rate) while also considering the feedforward effects of heart rate on BP. Our study is aimed at comparing modulations of feedback and feedforward couplings over 24 h in normotensive and hypertensive subjects, by assessing closed-loop baroreflex models in ambulatory conditions. Continuous intra-arterial BP recordings were performed for 24 h in eight normotensive and eight hypertensive subjects. Systolic BP (SBP) and pulse interval (PI) beat-by-beat series were analyzed by an autoregressive moving average model over …

Correction To: Determinant Roles Of Dendritic Cell-Expressed Notch Delta-Like And Jagged Ligands On Anti-Tumor T-Cell Immunity, Elena E. Tchekneva, Mounika U.L. Goruganthu, Roman V. Uzhachenko, Portia L. Thomas, Anneliese Antonucci, Irina Chekneva, Michael Koenig, Longzhu Piao, Anwari Akhter, Maria Teresa P. De Aquino, Paravathi Ranganathan, Nicholas Long, Thomas Magliery, Anna Valujskikh, Jason V. Evans, Rajeswara R. Arasada, Pierre P. Massion, David P. Carbone, Anil Shanker, Mikhail M. Dikov

Faculty & Staff Scholarship

Background: Notch intercellular communication instructs tissue-specific T-cell development and function. In this study, we explored the roles of dendritic cell (DC)-expressed Notch ligands in the regulation of T-cell effector function. Methods: We generated mice with CD11c lineage-specific deletion of Notch Delta-like ligand (Dll)1 and Jagged (Jag)2. Using these genetically-ablated mice and engineered pharmacological Notch ligand constructs, the roles of various Delta-like and Jagged ligands in the regulation of T-cell-mediated immunity were investigated. We assessed tumor growth, mouse survival, cytokine production, immunophenotyping of myeloid and lymphoid populations infiltrating the tumors, expression of checkpoint molecules and T-cell function in the experimental settings …

Trends In Suicide Among Youth Aged 10 To 19 Years In The United States, 1975 To 2016, Donna A. Ruch, Arielle H. Sheftall, Paige Schlagbaum, Joseph Rausch, John V. Campo, Jefferey A. Bridge

Faculty & Staff Scholarship

IMPORTANCE Suicide is a leading cause of death among youth aged 10 to 19 years in the United States, with rates traditionally higher in male than in female youth. Recent national mortality data suggest this gap may be narrowing, which warrants investigation. OBJECTIVE To investigate trends in suicide rates among US youth aged 10 to 19 years by age group, sex, race/ethnicity, and method of suicide. DESIGN, SETTING, AND PARTICIPANTS Cross-sectional study using period trend analysis of US suicide decedents aged 10 to 19 years from January 1, 1975, to December 31, 2016. Data were analyzed for periods defined by …

Quaternion-Based Robust Attitude Estimation Using An Adaptive Unscented Kalman Filter, Antonio C. B. Chiella, Bruno O. S. Teixeira, Guilherme A. S. Pereira

Faculty & Staff Scholarship

This paper presents the Quaternion-based Robust Adaptive Unscented Kalman Filter (QRAUKF) for attitude estimation. The proposed methodology modifies and extends the standard UKF equations to consistently accommodate the non-Euclidean algebra of unit quaternions and to add robustness to fast and slow variations in the measurement uncertainty. To deal with slow time-varying perturbations in the sensors, an adaptive strategy based on covariance matching that tunes the measurement covariance matrix online is used. Additionally, an outlier detector algorithm is adopted to identify abrupt changes in the UKF innovation, thus rejecting fast perturbations. Adaptation and outlier detection make the proposed algorithm robust to …

Ancient Polyploidy And Genome Evolution In Palms, Craig F. Barrett, Michael R. Mckain, Brandon T. Sinn, Xue Jun Ge, Yuqu Zhang, Alexandre Antonelli, Christine D. Bacon

Faculty & Staff Scholarship

Mechanisms of genome evolution are fundamental to our understanding of adaptation and the generation and maintenance of biodiversity, yet genome dynamics are still poorly characterized in many clades. Strong correlations between variation in genomic attributes and species diversity across the plant tree of life suggest that polyploidy or other mechanisms of genome size change confer selective advantages due to the introduction of genomic novelty. Palms (order Arecales, family Arecaceae) are diverse, widespread, and dominant in tropical ecosystems, yet little is known about genome evolution in this ecologically and economically important clade. Here, we take a phylogenetic comparative approach to investigate …