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Articles 4771 - 4800 of 11062
Full-Text Articles in Entire DC Network
Behavioral And Transcriptomic Analysis Of Trem2-Null Mice: Not All Knockout Mice Are Created Equal, Silvia S Kang, Aishe Kurti, Kelsey E Baker, Chia-Chen Liu, Marco Colonna, Jason D Ulrich, David M Holtzman, Guojun Bu, John D Fryer
Behavioral And Transcriptomic Analysis Of Trem2-Null Mice: Not All Knockout Mice Are Created Equal, Silvia S Kang, Aishe Kurti, Kelsey E Baker, Chia-Chen Liu, Marco Colonna, Jason D Ulrich, David M Holtzman, Guojun Bu, John D Fryer
2010-2019 OA Pubs
It is clear that innate immune system status is altered in numerous neurodegenerative diseases. Human genetic studies have demonstrated that triggering receptor expressed in myeloid cells 2 (TREM2) coding variants have a strong association with Alzheimer's disease (AD) and other neurodegenerative diseases. To more thoroughly understand the impact of TREM2 in vivo, we studied the behavioral and cognitive functions of wild-type (WT) and Trem2-/- (KO) mice during basal conditions and brain function in the context of innate immune stimulation with peripherally administered lipopolysaccharide (LPS). Early markers of neuroinflammation preceded Aif1 and Trem2 upregulation that occurred at later stages (24-48 h …
Zinc Inhibits Trpv1 To Alleviate Chemotherapy-Induced Neuropathic Pain, Jialie Luo, Alexis Bavencoffe, Pu Yang, Jing Feng, Shijin Yin, Aihua Qian, Weihua Yu, Shenbin Liu, Xuan Gong, Tao Cai, Edgar T. Walters, Carmen W. Dessauer, Hongzhen Hu
Zinc Inhibits Trpv1 To Alleviate Chemotherapy-Induced Neuropathic Pain, Jialie Luo, Alexis Bavencoffe, Pu Yang, Jing Feng, Shijin Yin, Aihua Qian, Weihua Yu, Shenbin Liu, Xuan Gong, Tao Cai, Edgar T. Walters, Carmen W. Dessauer, Hongzhen Hu
Open Access Publications
Zinc is a transition metal that has a long history of use as an anti-inflammatory agent. It also soothes pain sensations in a number of animal models. However, the effects and mechanisms of zinc on chemotherapy-induced peripheral neuropathy remain unknown. Here we show that locally injected zinc markedly reduces neuropathic pain in male and female mice induced by paclitaxel, a chemotherapy drug, in a TRPV1-dependent manner. Extracellularly applied zinc also inhibits the function of TRPV1 expressed in HEK293 cells and mouse DRG neurons, which requires the presence of zinc-permeable TRPA1 to mediate entry of zinc into the cytoplasm. Moreover, TRPA1 …
Pacs Viewbook 2018-2019, Program In Audiology And Communication Sciences
Pacs Viewbook 2018-2019, Program In Audiology And Communication Sciences
PACS News
No abstract provided.
Incorporating Reflection Boundary Conditions In The Neumann Series Radiative Transport Equation: Application To Photon Propagation And Reconstruction In Diffuse Optical Imaging, Abhinav K. Jha, Yansong Zhu, Simon Arridge, Dean F. Wong, Arman Rahmim
Incorporating Reflection Boundary Conditions In The Neumann Series Radiative Transport Equation: Application To Photon Propagation And Reconstruction In Diffuse Optical Imaging, Abhinav K. Jha, Yansong Zhu, Simon Arridge, Dean F. Wong, Arman Rahmim
Open Access Publications
No abstract provided.
Deletion Of Tsc2 In Nociceptors Reduces Target Innervation, Ion Channel Expression, And Sensitivity To Heat, Dan Carlin, Judith P. Golden, Amit Mogha, Vijay K. Samineni, Kelly R. Monk, Robert W. Gereau, Valeria Cavalli
Deletion Of Tsc2 In Nociceptors Reduces Target Innervation, Ion Channel Expression, And Sensitivity To Heat, Dan Carlin, Judith P. Golden, Amit Mogha, Vijay K. Samineni, Kelly R. Monk, Robert W. Gereau, Valeria Cavalli
Open Access Publications
No abstract provided.
Trpv1 Agonist, Capsaicin, Induces Axon Outgrowth After Injury Via Ca2+/Pka Signaling, Erin Frey, Scott Karney-Grobe, Trevor Krolak, Jeff Milbrandt, Aaron Diantonio
Trpv1 Agonist, Capsaicin, Induces Axon Outgrowth After Injury Via Ca2+/Pka Signaling, Erin Frey, Scott Karney-Grobe, Trevor Krolak, Jeff Milbrandt, Aaron Diantonio
Open Access Publications
No abstract provided.
The Genetic Underpinnings Of Variation In Ages At Menarche And Natural Menopause Among Women From The Multi-Ethnic Population Architecture Using Genomics And Epidemiology (Page) Study: A Trans-Ethnic Meta-Analysis, D. C. Rao, Karen Schwander, Et Al.
The Genetic Underpinnings Of Variation In Ages At Menarche And Natural Menopause Among Women From The Multi-Ethnic Population Architecture Using Genomics And Epidemiology (Page) Study: A Trans-Ethnic Meta-Analysis, D. C. Rao, Karen Schwander, Et Al.
Open Access Publications
No abstract provided.
Amphiregulin Modifies The Minnesota Acute Graft-Versus-Host Disease Risk Score: Results From Bmt Ctn 0302/0802, Iskra Pusic
Amphiregulin Modifies The Minnesota Acute Graft-Versus-Host Disease Risk Score: Results From Bmt Ctn 0302/0802, Iskra Pusic
Open Access Publications
No abstract provided.
Magic Angle Spinning Spheres, Pinhui Chen, Brice J. Albert, Chukun Gao, Nicholas Alaniva, Lauren E. Price, Faith J. Scott, Edward P. Saliba, Erika L. Sesti, Patrick T. Judge, Edward W. Fisher, Alexander B. Barnes
Magic Angle Spinning Spheres, Pinhui Chen, Brice J. Albert, Chukun Gao, Nicholas Alaniva, Lauren E. Price, Faith J. Scott, Edward P. Saliba, Erika L. Sesti, Patrick T. Judge, Edward W. Fisher, Alexander B. Barnes
Open Access Publications
No abstract provided.
Epithelial Vertex Models With Active Biochemical Regulation Of Contractility Can Explain Organized Collective Cell Motility, Sarita Koride, Andrew J. Loza, Sean X. Sun
Epithelial Vertex Models With Active Biochemical Regulation Of Contractility Can Explain Organized Collective Cell Motility, Sarita Koride, Andrew J. Loza, Sean X. Sun
Open Access Publications
No abstract provided.
A Brain Electrical Activity Electroencephalographic-Based Biomarker Of Functional Impairment In Traumatic Brain Injury: A Multi-Site Validation Trial, Daniel Hanley, Leslie S. Prichep, Neeraj Badjatia, Jeffrey Bazarian, Richard Chiacchierini, Kenneth C. Curley, John Garrett, Elizabeth Jones, Rosanne Naunheim, Brian O'Neil, John O'Neill, David W. Wright, J. Stephen Huff
A Brain Electrical Activity Electroencephalographic-Based Biomarker Of Functional Impairment In Traumatic Brain Injury: A Multi-Site Validation Trial, Daniel Hanley, Leslie S. Prichep, Neeraj Badjatia, Jeffrey Bazarian, Richard Chiacchierini, Kenneth C. Curley, John Garrett, Elizabeth Jones, Rosanne Naunheim, Brian O'Neil, John O'Neill, David W. Wright, J. Stephen Huff
Open Access Publications
No abstract provided.
Feasibility Of Co-Registered Ultrasound And Acoustic-Resolution Photoacoustic Imaging Of Human Colorectal Cancer, Xiandong Leng, William Chapman, Bin Rao, Sreyankar Nandy, Ruimin Chen, Rehan Rais, Ivan Gonzalez, Qifa Zhou, Deyali Chatterjee, Matthew Mutch, Quing Zhu
Feasibility Of Co-Registered Ultrasound And Acoustic-Resolution Photoacoustic Imaging Of Human Colorectal Cancer, Xiandong Leng, William Chapman, Bin Rao, Sreyankar Nandy, Ruimin Chen, Rehan Rais, Ivan Gonzalez, Qifa Zhou, Deyali Chatterjee, Matthew Mutch, Quing Zhu
Open Access Publications
No abstract provided.
Reprogramming Glioblastoma Multiforme Cells Into Neurons By Protein Kinase Inhibitors, Jie Yuan, Fan Zhang, Dennis Hallahan, Zhen Zhang, Liming He, Ling-Gang Wu, Meng You, Qin Yang
Reprogramming Glioblastoma Multiforme Cells Into Neurons By Protein Kinase Inhibitors, Jie Yuan, Fan Zhang, Dennis Hallahan, Zhen Zhang, Liming He, Ling-Gang Wu, Meng You, Qin Yang
Open Access Publications
No abstract provided.
15q23 Gain In A Neonate With A Giant Omphalocele And Multiple Co-Occurring Anomalies, Hui-Fang Zhou, Christopher J. O'Conor, Chiraag Gangahar, Louis P. Dehner
15q23 Gain In A Neonate With A Giant Omphalocele And Multiple Co-Occurring Anomalies, Hui-Fang Zhou, Christopher J. O'Conor, Chiraag Gangahar, Louis P. Dehner
Open Access Publications
No abstract provided.
Mycobacterium Tuberculosis Type Vii Secretion System Effectors Differentially Impact The Escrt Endomembrane Damage Response, Ekansh Mittal, Michael L. Skowyra, Grace Uwase, Emir Tinaztepe, Alka Mehra, Stefan Köster, Phyllis I. Hanson, Jennifer A. Philips
Mycobacterium Tuberculosis Type Vii Secretion System Effectors Differentially Impact The Escrt Endomembrane Damage Response, Ekansh Mittal, Michael L. Skowyra, Grace Uwase, Emir Tinaztepe, Alka Mehra, Stefan Köster, Phyllis I. Hanson, Jennifer A. Philips
Open Access Publications
No abstract provided.
Phase I Studies Of Azd1208, A Proviral Integration Moloney Virus Kinase Inhibitor In Solid And Haematological Cancers, Geoffrey L. Uy, Et Al
Phase I Studies Of Azd1208, A Proviral Integration Moloney Virus Kinase Inhibitor In Solid And Haematological Cancers, Geoffrey L. Uy, Et Al
Open Access Publications
No abstract provided.
Combining Immunotherapy With Radiation Therapy In Thoracic Oncology, Shahed N. Badiyan, Michael C. Roach, Michael D. Chuong, Stephanie R. Rice, Nasarachi E. Onyeuku, Jill Remick, Srinivas Chilukuri, Erica Glass, Pranshu Mohindra, Charles B. Simone Ii
Combining Immunotherapy With Radiation Therapy In Thoracic Oncology, Shahed N. Badiyan, Michael C. Roach, Michael D. Chuong, Stephanie R. Rice, Nasarachi E. Onyeuku, Jill Remick, Srinivas Chilukuri, Erica Glass, Pranshu Mohindra, Charles B. Simone Ii
Open Access Publications
No abstract provided.
Gpr56/Adgrg1 Regulates Development And Maintenance Of Peripheral Myelin, Sarah D. Ackerman, Amit Mogha, Breanne L. Harty, Mitchell D'Rozario, Nicholas E. Sanchez, Paul Gamble, Matthew R. Macewan, Wilson Zachary Ray, Kelly R. Monk, Et Al
Gpr56/Adgrg1 Regulates Development And Maintenance Of Peripheral Myelin, Sarah D. Ackerman, Amit Mogha, Breanne L. Harty, Mitchell D'Rozario, Nicholas E. Sanchez, Paul Gamble, Matthew R. Macewan, Wilson Zachary Ray, Kelly R. Monk, Et Al
Open Access Publications
No abstract provided.
Antenatal Spontaneous Renal Forniceal Rupture Presenting As An Acute Abdomen, Jennifer Travieso, Omar M. Young
Antenatal Spontaneous Renal Forniceal Rupture Presenting As An Acute Abdomen, Jennifer Travieso, Omar M. Young
Open Access Publications
No abstract provided.
Construction, Expression, And Characterization Of Rsea-Egf And In Vitro Evaluation Of Its Antitumor Activity Against Nasopharyngeal Cancer, Xueting Liu, Liping Zeng, Zhongqiu Zhou, Yang Xie, Shan Wang, Junyan Zhang, Ying He, Zehong Zou, Jianguo Zhang, Ailin Tao
Construction, Expression, And Characterization Of Rsea-Egf And In Vitro Evaluation Of Its Antitumor Activity Against Nasopharyngeal Cancer, Xueting Liu, Liping Zeng, Zhongqiu Zhou, Yang Xie, Shan Wang, Junyan Zhang, Ying He, Zehong Zou, Jianguo Zhang, Ailin Tao
Open Access Publications
No abstract provided.
Synthesis And Evaluation Of Troponoids As A New Class Of Antibiotics, Feng Cao, Cari Orth, Maureen J. Donlin, Patrick Adegboyega, Marvin J. Meyers, Ryan P. Murelli, Mohamed Elagawany, Bahaa Elgendy, John E. Tavis
Synthesis And Evaluation Of Troponoids As A New Class Of Antibiotics, Feng Cao, Cari Orth, Maureen J. Donlin, Patrick Adegboyega, Marvin J. Meyers, Ryan P. Murelli, Mohamed Elagawany, Bahaa Elgendy, John E. Tavis
Open Access Publications
No abstract provided.
The Toxoplasma Gondii Active Serine Hydrolase 4 Regulates Parasite Division And Intravacuolar Parasite Architecture, Ian T. Foe, Ouma Onguka, Katherine Amberg-Johnson, Rikki M. Garner, Neri Amara, Wandy Beatty, Ellen Yeh, Matthew Bogyo
The Toxoplasma Gondii Active Serine Hydrolase 4 Regulates Parasite Division And Intravacuolar Parasite Architecture, Ian T. Foe, Ouma Onguka, Katherine Amberg-Johnson, Rikki M. Garner, Neri Amara, Wandy Beatty, Ellen Yeh, Matthew Bogyo
Open Access Publications
No abstract provided.
Washington University Magazine, Fall/Winter 2018-2019
Washington University Magazine, Fall/Winter 2018-2019
Washington University Magazine
No abstract provided.
Washington University Magazine, Spring 2018
Washington University Magazine, Spring 2018
Washington University Magazine
No abstract provided.
The Immediate Early Gene Egr3 Is Required For Hippocampal Induction Of Bdnf By Electroconvulsive Stimulation, Kimberly T. Meyers, Ketan K. Marballi, Samuel J. Brunwasser, Briana Renda, Milad Charbel, Diano F. Marrone, Amelia L. Gallitano
The Immediate Early Gene Egr3 Is Required For Hippocampal Induction Of Bdnf By Electroconvulsive Stimulation, Kimberly T. Meyers, Ketan K. Marballi, Samuel J. Brunwasser, Briana Renda, Milad Charbel, Diano F. Marrone, Amelia L. Gallitano
Open Access Publications
No abstract provided.
Positron Emission Tomography (Pet) For Prediction Of Glioma Histology: Protocol For An Individual-Level Data Meta-Analysis Of Test Performance, Nikolaos A. Trikalinos, Takashi Nihashi, Evangelos Evangelou, Teruhiko Terasawa
Positron Emission Tomography (Pet) For Prediction Of Glioma Histology: Protocol For An Individual-Level Data Meta-Analysis Of Test Performance, Nikolaos A. Trikalinos, Takashi Nihashi, Evangelos Evangelou, Teruhiko Terasawa
Open Access Publications
No abstract provided.
Characterization Of Small Molecules Inhibiting The Pro-Angiogenic Activity Of The Zinc Finger Transcription Factor Vezf1, Ming He, Qianyi Yang, Allison B. Norvil, David Sherris, Humaira Gowher
Characterization Of Small Molecules Inhibiting The Pro-Angiogenic Activity Of The Zinc Finger Transcription Factor Vezf1, Ming He, Qianyi Yang, Allison B. Norvil, David Sherris, Humaira Gowher
Open Access Publications
No abstract provided.
The Presentation Of The Mind-Brain Problem In Leading Psychiatry Journals, Alexander Moreira-Almeida, Saulo De F. Araujo, C. Robert Cloninger
The Presentation Of The Mind-Brain Problem In Leading Psychiatry Journals, Alexander Moreira-Almeida, Saulo De F. Araujo, C. Robert Cloninger
Open Access Publications
No abstract provided.
An Integrated Clinical Program And Crowdsourcing Strategy For Genomic Sequencing And Mendelian Disease Gene Discovery, Nathan O. Stitziel, Et Al
An Integrated Clinical Program And Crowdsourcing Strategy For Genomic Sequencing And Mendelian Disease Gene Discovery, Nathan O. Stitziel, Et Al
Open Access Publications
No abstract provided.
New Insights Into The Role Of Trem2 In Alzheimer’S Disease, Maud Gratuze, Cheryl E.G. Leyns, David M. Holtzman
New Insights Into The Role Of Trem2 In Alzheimer’S Disease, Maud Gratuze, Cheryl E.G. Leyns, David M. Holtzman
Open Access Publications
No abstract provided.