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Washington University School of Medicine

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Implementation Of Wearable Sensing Technology For Movement: Pushing Forward Into The Routine Physical Rehabilitation Care Field, Catherine E Lang, Jessica Barth, Carey L Holleran, Jeff D Konrad, Marghuretta D Bland Jan 2020

Implementation Of Wearable Sensing Technology For Movement: Pushing Forward Into The Routine Physical Rehabilitation Care Field, Catherine E Lang, Jessica Barth, Carey L Holleran, Jeff D Konrad, Marghuretta D Bland

Open Access Publications

While the promise of wearable sensor technology to transform physical rehabilitation has been around for a number of years, the reality is that wearable sensor technology for the measurement of human movement has remained largely confined to rehabilitation research labs with limited ventures into clinical practice. The purposes of this paper are to: (1) discuss the major barriers in clinical practice and available wearable sensing technology; (2) propose benchmarks for wearable device systems that would make it feasible to implement them in clinical practice across the world and (3) evaluate a current wearable device system against the benchmarks as an …


Online And Clicker Quizzing On Jargon Terms Enhances Definition-Focused But Not Conceptually Focused Biology Exam Performance, Steven C. Pan, James Cooke, Jeri L. Little, Mark A. Mcdaniel, Erin R. Foster, Lisa Tabor Connor, Timothy C. Rickard Dec 2019

Online And Clicker Quizzing On Jargon Terms Enhances Definition-Focused But Not Conceptually Focused Biology Exam Performance, Steven C. Pan, James Cooke, Jeri L. Little, Mark A. Mcdaniel, Erin R. Foster, Lisa Tabor Connor, Timothy C. Rickard

Open Access Publications

Mastery of jargon terms is an important part of student learning in biology and other science, technology, engineering, and mathematics domains. In two experiments, we investigated whether prelecture quizzes enhance memory for jargon terms, and whether that enhanced familiarity can facilitate learning of related concepts that are encountered during subsequent lectures and readings. Undergraduate students enrolled in neuroanatomy and physiology courses completed 10-minute low-stakes quizzes with feedback on jargon terms either online (experiment 1) or using in-class clickers (experiment 2). Quizzes occurred before conventional course instruction in which the terms were used. On exams occurring up to 12 weeks later, …


Gut Microbiota: From The Forgotten Organ To A Potential Key Player In The Pathology Of Alzheimer's Disease, Dong-Oh Seo, David M Holtzman Nov 2019

Gut Microbiota: From The Forgotten Organ To A Potential Key Player In The Pathology Of Alzheimer's Disease, Dong-Oh Seo, David M Holtzman

Open Access Publications

More than 300 years ago, Antony van Leewenhoeck first described observing single-celled microorganisms, which he termed "animalcules," examining his saliva under a microscope. Although the idea of the coexistence of microorganisms in our body is not new, we have only recently been able to investigate their ecological relationship to our body, with the development of high-throughput molecular techniques. The diverse microorganism communities residing in our guts are established and maintained by complex interactions among microorganisms and their host. Notably, their alteration has been implicated in influencing various diseases including neurological diseases. Alzheimer's disease (AD) is the most common cause of …


A Mutation In Site-1 Protease Is Associated With A Complex Phenotype That Includes Episodic Hyperckemia And Focal Myoedema, George G. Schweitzer, Connie Gan, Robert C. Bucelli, Daniel Wegner, Robert E. Schmidt, Marwan Shinawi, Brian N. Finck, Rita T. Brookheart Jan 2019

A Mutation In Site-1 Protease Is Associated With A Complex Phenotype That Includes Episodic Hyperckemia And Focal Myoedema, George G. Schweitzer, Connie Gan, Robert C. Bucelli, Daniel Wegner, Robert E. Schmidt, Marwan Shinawi, Brian N. Finck, Rita T. Brookheart

Open Access Publications

No abstract provided.


Top 10 Research Priorities In Spatial Lifecourse Epidemiology, Peng Jia, Ross C. Brownson, Et Al. Jan 2019

Top 10 Research Priorities In Spatial Lifecourse Epidemiology, Peng Jia, Ross C. Brownson, Et Al.

Open Access Publications

No abstract provided.


Outlook Magazine, Winter 2018 Jan 2018

Outlook Magazine, Winter 2018

Outlook Magazine

No abstract provided.


High-Throughput Scaffold-Free Microtissues Through 3d Printing, Christen J. Boyer, David H. Ballard, Mansoureh Barzegar, J. Winny Yun, Jennifer E. Woerner, Ghali E. Ghali, Moheb Boktor, Yuping Wang, J. Steven Alexander Jan 2018

High-Throughput Scaffold-Free Microtissues Through 3d Printing, Christen J. Boyer, David H. Ballard, Mansoureh Barzegar, J. Winny Yun, Jennifer E. Woerner, Ghali E. Ghali, Moheb Boktor, Yuping Wang, J. Steven Alexander

Open Access Publications

No abstract provided.


A Systematic Meta-Analysis Of Oxygen-To-Glucose And Oxygen-To-Carbohydrate Ratios In The Resting Human Brain, Tyler Blazey, Abraham Z. Snyder, Manu S. Goyal, Andrei G. Vlassenko, Marcus E. Raichle Jan 2018

A Systematic Meta-Analysis Of Oxygen-To-Glucose And Oxygen-To-Carbohydrate Ratios In The Resting Human Brain, Tyler Blazey, Abraham Z. Snyder, Manu S. Goyal, Andrei G. Vlassenko, Marcus E. Raichle

Open Access Publications

No abstract provided.


Short-Wavelength Light-Blocking Eyeglasses Attenuate Symptoms Of Eye Fatigue, Jonathan B. Lin, Blair W. Gerratt, Carl J. Bassi, Rajendra S. Apte Jan 2016

Short-Wavelength Light-Blocking Eyeglasses Attenuate Symptoms Of Eye Fatigue, Jonathan B. Lin, Blair W. Gerratt, Carl J. Bassi, Rajendra S. Apte

Open Access Publications

No abstract provided.


Nicotinamide Mononucleotide Supplementation Reverses Vascular Dysfunction And Oxidative Stress With Aging In Mice, Natalie E. De Picciotto, Lindsey B. Gano, Lawrence C. Johnson, Christopher R. Martens, Amy L. Sindler, Kathryn F. Mills, Shin-Ichiro Imai, Douglas R. Seals Jan 2016

Nicotinamide Mononucleotide Supplementation Reverses Vascular Dysfunction And Oxidative Stress With Aging In Mice, Natalie E. De Picciotto, Lindsey B. Gano, Lawrence C. Johnson, Christopher R. Martens, Amy L. Sindler, Kathryn F. Mills, Shin-Ichiro Imai, Douglas R. Seals

Open Access Publications

No abstract provided.


Angiotensin Converting Enzyme (Ace) Inhibitor Extends Caenorhabditis Elegans Life Span, Sandeep Kumar, Nicholas Dietrich, Kerry Kornfeld Jan 2016

Angiotensin Converting Enzyme (Ace) Inhibitor Extends Caenorhabditis Elegans Life Span, Sandeep Kumar, Nicholas Dietrich, Kerry Kornfeld

Open Access Publications

No abstract provided.


An Approach To Quantifying 3d Responses Of Cells To Extreme Strain, Yuhui Li, Guoyou Huang, Moxiao Li, Lin Wang, Elliot L. Elson, Tian Jian Lu, Guy M. Genin, Feng Xu Jan 2016

An Approach To Quantifying 3d Responses Of Cells To Extreme Strain, Yuhui Li, Guoyou Huang, Moxiao Li, Lin Wang, Elliot L. Elson, Tian Jian Lu, Guy M. Genin, Feng Xu

Open Access Publications

No abstract provided.


Effects Of Vitamin D Supplementation On C-Peptide And 25-Hydroxyvitamin D Concentrations At 3 And 6 Months, Paulette D. Chandler, Edward L. Giovannucci, Jamil B. Scott, Gary G. Bennett, Kimmie Ng, Andrew T. Chan, Bruce W. Hollis, Nader Rifai, Karen M. Emmons, Charles S. Fuchs, Bettina F. Drake Jan 2015

Effects Of Vitamin D Supplementation On C-Peptide And 25-Hydroxyvitamin D Concentrations At 3 And 6 Months, Paulette D. Chandler, Edward L. Giovannucci, Jamil B. Scott, Gary G. Bennett, Kimmie Ng, Andrew T. Chan, Bruce W. Hollis, Nader Rifai, Karen M. Emmons, Charles S. Fuchs, Bettina F. Drake

Open Access Publications

No abstract provided.


Bjc Today Feb 2014

Bjc Today

BJC Today

No abstract provided.


Bjc Today Apr 2013

Bjc Today

BJC Today

No abstract provided.


Mechanisms Of Hypoglycemia-Associated Autonomic Failure In Diabetes, Philip E. Cryer Jan 2013

Mechanisms Of Hypoglycemia-Associated Autonomic Failure In Diabetes, Philip E. Cryer

Open Access Publications

No abstract provided.


Bjc Today Mar 2012

Bjc Today

BJC Today

No abstract provided.


Tbc1d3, A Hominoid-Specific Gene, Delays Irs-1 Degradation And Promotes Insulin Signaling By Modulating P70 S6 Kinase Activity, Marisa J. Wainszelbaum, Jialu Liu, Chen Kong, Priya Srikanth, Dmitri Samovski, Xiong Su, Philip D. Stahl Jan 2012

Tbc1d3, A Hominoid-Specific Gene, Delays Irs-1 Degradation And Promotes Insulin Signaling By Modulating P70 S6 Kinase Activity, Marisa J. Wainszelbaum, Jialu Liu, Chen Kong, Priya Srikanth, Dmitri Samovski, Xiong Su, Philip D. Stahl

Open Access Publications

No abstract provided.


Three Ontologies To Define Phenotype Measurement Data, Mary Shimoyama, Rajni Nigam, Leslie Sanders Mcintosh, Rakesh Nagarajan, Treva Rice, D. C. Rao, Melinda R. Dwinell Jan 2012

Three Ontologies To Define Phenotype Measurement Data, Mary Shimoyama, Rajni Nigam, Leslie Sanders Mcintosh, Rakesh Nagarajan, Treva Rice, D. C. Rao, Melinda R. Dwinell

Open Access Publications

No abstract provided.


Ubiquitination And Degradation Of The Hominoid- Specific Oncoprotein Tbc1d3 Is Mediated By Cul7 E3 Ligase, Chen Kong, Dmitri Samovski, Priya Srikanth, Marisa J. Wainszelbaum, Audra J. Charron, Jialiu Liu, Jeffrey J. Lange, Pin-I Chen, Zhen-Qiang Pan, Xiong Su, Philip D. Stahl Jan 2012

Ubiquitination And Degradation Of The Hominoid- Specific Oncoprotein Tbc1d3 Is Mediated By Cul7 E3 Ligase, Chen Kong, Dmitri Samovski, Priya Srikanth, Marisa J. Wainszelbaum, Audra J. Charron, Jialiu Liu, Jeffrey J. Lange, Pin-I Chen, Zhen-Qiang Pan, Xiong Su, Philip D. Stahl

Open Access Publications

No abstract provided.


Pcr-Based Genotyping Of Helicobacter Pylori Of Gambian Children And Adults Directly From Biopsy Specimens And Bacterial Cultures, Ousman Secka, Martin Antonio, Mary Tapgun, Douglas E. Berg, Christian Bottomley, Vivat Thomas, Robert Walton, Tumani Corrah, Richard A. Adegbola, Julian E. Thomas Jan 2011

Pcr-Based Genotyping Of Helicobacter Pylori Of Gambian Children And Adults Directly From Biopsy Specimens And Bacterial Cultures, Ousman Secka, Martin Antonio, Mary Tapgun, Douglas E. Berg, Christian Bottomley, Vivat Thomas, Robert Walton, Tumani Corrah, Richard A. Adegbola, Julian E. Thomas

Open Access Publications

No abstract provided.


Research With Human Subjects, Sarah Fowler-Dixon Jan 2011

Research With Human Subjects, Sarah Fowler-Dixon

Human Research Protection Program (HRPP) Education

No abstract provided.


Identification Of Chemically Sulfated/Desulfated Glycosaminoglycans In Contaminated Heparins And Development Of A Simple Assay For The Detection Of Most Contaminants In Heparin, Jing Pan, Yi Qian, Xiaodong Zhou, Andrew Pazandak, Sarah B. Frazier, Peter Weiser, Hong Lu, Lijuan Zhang Jan 2010

Identification Of Chemically Sulfated/Desulfated Glycosaminoglycans In Contaminated Heparins And Development Of A Simple Assay For The Detection Of Most Contaminants In Heparin, Jing Pan, Yi Qian, Xiaodong Zhou, Andrew Pazandak, Sarah B. Frazier, Peter Weiser, Hong Lu, Lijuan Zhang

Open Access Publications

No abstract provided.


Fibroblast Growth Factor Receptors 1 And 2 In Keratinocytes Control The Epidermal Barrier And Cutaneous Homeostasis, Jingxuan Yang, Michael Meyer, Anna-Katharina Müller, Friederike Böhm, Richard Grose, Tina Dauwalder, Francois Verrey, Manfred Kopf, Juha Partanen, Wilhelm Bloch, David M. Ornitz, Sabine Werner Jan 2010

Fibroblast Growth Factor Receptors 1 And 2 In Keratinocytes Control The Epidermal Barrier And Cutaneous Homeostasis, Jingxuan Yang, Michael Meyer, Anna-Katharina Müller, Friederike Böhm, Richard Grose, Tina Dauwalder, Francois Verrey, Manfred Kopf, Juha Partanen, Wilhelm Bloch, David M. Ornitz, Sabine Werner

Open Access Publications

Fibroblast growth factors (FGFs) are master regulators of organogenesis and tissue homeostasis. In this study, we used different combinations of FGF receptor (FGFR)-deficient mice to unravel their functions in the skin. Loss of the IIIb splice variants of FGFR1 and FGFR2 in keratinocytes caused progressive loss of skin appendages, cutaneous inflammation, keratinocyte hyperproliferation, and acanthosis. We identified loss of FGF-induced expression of tight junction components with subsequent deficits in epidermal barrier function as the mechanism underlying the progressive inflammatory skin disease. The defective barrier causes activation of keratinocytes and epidermal gammadelta T cells, which produce interleukin-1 family member 8 and …


Defensins And The Convergent Evolution Of Platypus And Reptile Venom Genes, Camilla M. Whittington, Anthony T. Papenfuss, Paramjit Bansal, Allan M. Torres, Emily S.W. Wong, Janine E. Deakin, Tina Graves, Amber Alsop, Kyriena Schatzkamer, Colin Kremitzki, Chris P. Ponting, Peter Temple-Smith, Wesley C. Warren, Philip W. Kuchel, Katherine Belov Jan 2008

Defensins And The Convergent Evolution Of Platypus And Reptile Venom Genes, Camilla M. Whittington, Anthony T. Papenfuss, Paramjit Bansal, Allan M. Torres, Emily S.W. Wong, Janine E. Deakin, Tina Graves, Amber Alsop, Kyriena Schatzkamer, Colin Kremitzki, Chris P. Ponting, Peter Temple-Smith, Wesley C. Warren, Philip W. Kuchel, Katherine Belov

Open Access Publications

No abstract provided.


Nested Patch Pcr Enables Highly Multiplexed Mutation Discovery In Candidate Genes, Katherine Elena Varley, Robi David Mitra Jan 2008

Nested Patch Pcr Enables Highly Multiplexed Mutation Discovery In Candidate Genes, Katherine Elena Varley, Robi David Mitra

Open Access Publications

No abstract provided.


New Challenges In Studying Nutrition-Disease Interactions In The Developing World, Andrew M. Prentice, M. Eric Gershwin, Ulrich E. Schaible, Gerald T. Keusch, Cesar G. Victora, Jeffrey I. Gordon Jan 2008

New Challenges In Studying Nutrition-Disease Interactions In The Developing World, Andrew M. Prentice, M. Eric Gershwin, Ulrich E. Schaible, Gerald T. Keusch, Cesar G. Victora, Jeffrey I. Gordon

Open Access Publications

No abstract provided.


Large-Scale In Silico Mapping Of Complex Quantitative Traits In Inbred Mice, Pengyuan Liu, Haris Vikis, Yan Lu, Daolong Wang, Ming You Jan 2007

Large-Scale In Silico Mapping Of Complex Quantitative Traits In Inbred Mice, Pengyuan Liu, Haris Vikis, Yan Lu, Daolong Wang, Ming You

Open Access Publications

No abstract provided.


Washington University Record, September 1, 2006 Sep 2006

Washington University Record, September 1, 2006

Washington University Record

No abstract provided.


Genomic And Metabolic Studies Of The Impact Of Probiotics On A Model Gut Symbiont And Host, Justin L. Sonnenburg, Christina T. Chen, Jeffery I. Gordon Jan 2006

Genomic And Metabolic Studies Of The Impact Of Probiotics On A Model Gut Symbiont And Host, Justin L. Sonnenburg, Christina T. Chen, Jeffery I. Gordon

Open Access Publications

No abstract provided.