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Washington University School of Medicine

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Articles 14551 - 14580 of 20412

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A Clustering Analysis Of Lipoprotein Diameters In The Metabolic Syndrome, Alexis C. Frazier-Wood, Stephen Glasser, W Timothy Garvey, Edmond K. Kabagambe, Ingrid B. Borecki, Hemant K. Tiwari, Michael Y. Tsai, Paul N. Hopkins, Jose M. Ordovas, Donna K. Arnett Jan 2011

A Clustering Analysis Of Lipoprotein Diameters In The Metabolic Syndrome, Alexis C. Frazier-Wood, Stephen Glasser, W Timothy Garvey, Edmond K. Kabagambe, Ingrid B. Borecki, Hemant K. Tiwari, Michael Y. Tsai, Paul N. Hopkins, Jose M. Ordovas, Donna K. Arnett

Open Access Publications

No abstract provided.


Resorufin Analogs Preferentially Bind Cerebrovascular Amyloid: Potential Use As Imaging Ligands For Cerebral Amyloid Angiopathy, Byung Hee Han, Meng-Liang Zhou, Ananth K. Vellimana, Eric Milner, David H. Kim, Jacob K. Greenberg, Wenhua Chu, Robert H. Mach, Gregory J. Zipfel Jan 2011

Resorufin Analogs Preferentially Bind Cerebrovascular Amyloid: Potential Use As Imaging Ligands For Cerebral Amyloid Angiopathy, Byung Hee Han, Meng-Liang Zhou, Ananth K. Vellimana, Eric Milner, David H. Kim, Jacob K. Greenberg, Wenhua Chu, Robert H. Mach, Gregory J. Zipfel

Open Access Publications

No abstract provided.


Type I Interferon Negatively Controls Plasmacytoid Dendritic Cell Numbers In Vivo, Melissa Swiecki, Yaming Wang, William Vermi, Susan Gilfillan, Robert D. Schreiber, Marco Colonna Jan 2011

Type I Interferon Negatively Controls Plasmacytoid Dendritic Cell Numbers In Vivo, Melissa Swiecki, Yaming Wang, William Vermi, Susan Gilfillan, Robert D. Schreiber, Marco Colonna

Open Access Publications

No abstract provided.


Memory B Cells, But Not Long-Lived Plasma Cells, Possess Antigen Specificities For Viral Escape Mutants, Whitney E. Purtha, Thomas F. Tedder, Syd Johnson, Deepta Bhattacharya, Michael S. Diamond Jan 2011

Memory B Cells, But Not Long-Lived Plasma Cells, Possess Antigen Specificities For Viral Escape Mutants, Whitney E. Purtha, Thomas F. Tedder, Syd Johnson, Deepta Bhattacharya, Michael S. Diamond

Open Access Publications

No abstract provided.


Bjc Today Dec 2010

Bjc Today

BJC Today

No abstract provided.


Midazolam Inhibits Hippocampal Long-Term Potentiation And Learning Through Dual Central And Peripheral Benzodiazepine Receptor Activation And Neurosteroidogenesis, Kazuhiro Tokuda, Kazuko A. O'Dell, Yukitoshi Izumi, Charles F. Zorumski Dec 2010

Midazolam Inhibits Hippocampal Long-Term Potentiation And Learning Through Dual Central And Peripheral Benzodiazepine Receptor Activation And Neurosteroidogenesis, Kazuhiro Tokuda, Kazuko A. O'Dell, Yukitoshi Izumi, Charles F. Zorumski

Open Access Publications

Benzodiazepines (BDZs) enhance GABA(A) receptor inhibition by direct actions on central BDZ receptors (CBRs). Although some BDZs also bind mitochondrial receptors [translocator protein (18 kDa) (TSPO)] and promote the synthesis of GABA-enhancing neurosteroids, the role of neurosteroids in the clinical effects of BDZs is unknown. In rat hippocampal slices, we compared midazolam, an anesthetic BDZ, with clonazepam, an anticonvulsant/anxiolytic BDZ that activates CBRs selectively. Midazolam, but not clonazepam, increased neurosteroid levels in CA1 pyramidal neurons without changing TSPO immunostaining. Midazolam, but not clonazepam, also augmented a form of spike inhibition after stimulation adjacent to the pyramidal cell layer and inhibited …


Golgi Cells Operate As State-Specific Temporal Filters At The Input Stage Of The Cerebellar Cortex, Shane A. Heine, Stephen M. Highstein, Pablo M. Blazquez Dec 2010

Golgi Cells Operate As State-Specific Temporal Filters At The Input Stage Of The Cerebellar Cortex, Shane A. Heine, Stephen M. Highstein, Pablo M. Blazquez

Open Access Publications

Cerebellar processing of incoming information begins at the synapse between mossy fibers and granule cells, a synapse that is strongly controlled through Golgi cell inhibition. Thus, Golgi cells are uniquely positioned to control the flow of information into the cerebellar cortex and understanding their responses during behavior is essential to understanding cerebellar function. Here we show, for the first time, that Golgi cells express a unique oculomotor-related signal that can be used to provide state- and time-specific filtering of granule cell activity. We used newly established criteria to identify the unique electrophysiological signature of Golgi cells and recorded these neurons …


Bjc Today Dec 2010

Bjc Today

BJC Today

No abstract provided.


The Contraceptive Choice Project: Recruiting Women At Highest Risk For Unintended Pregnancy And Sexually Transmitted Infection, Janine E. Spain, Jeffrey F. Peipert, Tessa Madden, Jenifer E. Allsworth, Gina M. Secura Nov 2010

The Contraceptive Choice Project: Recruiting Women At Highest Risk For Unintended Pregnancy And Sexually Transmitted Infection, Janine E. Spain, Jeffrey F. Peipert, Tessa Madden, Jenifer E. Allsworth, Gina M. Secura

Open Access Publications

No abstract provided.


Bjc Today Nov 2010

Bjc Today

BJC Today

No abstract provided.


Symptomatic Progression Of Asymptomatic Rotator Cuff Tears A Prospective Study Of Clinical And Sonographic Variables, Nathan A. Mall, H. Mike Kim, Jay D. Keener, Karen Steger-May, Sharlene A. Teefey, William D. Middleton, Georgia Stobbs, Ken Yamaguchi Nov 2010

Symptomatic Progression Of Asymptomatic Rotator Cuff Tears A Prospective Study Of Clinical And Sonographic Variables, Nathan A. Mall, H. Mike Kim, Jay D. Keener, Karen Steger-May, Sharlene A. Teefey, William D. Middleton, Georgia Stobbs, Ken Yamaguchi

Open Access Publications

No abstract provided.


Bjc Today Nov 2010

Bjc Today

BJC Today

No abstract provided.


Bjc Today Oct 2010

Bjc Today

BJC Today

No abstract provided.


Membrane Anchoring Subunits Specify Selective Regulation Of Rgs9·Gbeta5 Gap Complex In Photoreceptor Neurons, Yan Cao, Alexander V. Kolesnikov, Ikuo Masuho, Vladimir J. Kefalov, Kirill A. Martemyanov Oct 2010

Membrane Anchoring Subunits Specify Selective Regulation Of Rgs9·Gbeta5 Gap Complex In Photoreceptor Neurons, Yan Cao, Alexander V. Kolesnikov, Ikuo Masuho, Vladimir J. Kefalov, Kirill A. Martemyanov

Open Access Publications

The RGS9·Gβ5 complex is the key regulator of neuronal G-protein signaling and shows remarkable selectivity of subunit composition. In retinal photoreceptors, RGS9·Gβ5 is bound to the membrane anchor R9AP and the complex regulates visual signaling. In the basal ganglia neurons, RGS9·Gβ5 is instead associated with a homologous protein, R7BP, and regulates reward circuit. Switching this selective subunit composition of the complex in rod photoreceptors allowed us to study the molecular underpinning of signaling specificity in diverse G-protein pathways. We have found that both membrane anchoring subunits play a conserved role in regulating protein levels of RGS9·Gβ5 and enhancing the ability …


Report From The 2009 Aoa North American Traveling Fellowship, Ryan T. Bicknell, Gregory J. Della Rocca, Wellington K. Hsu, Amanda D. Marshall, Robert H. Brophy Oct 2010

Report From The 2009 Aoa North American Traveling Fellowship, Ryan T. Bicknell, Gregory J. Della Rocca, Wellington K. Hsu, Amanda D. Marshall, Robert H. Brophy

Open Access Publications

No abstract provided.


Bjc Today Oct 2010

Bjc Today

BJC Today

No abstract provided.


Protein Turnover Of The Wallenda/Dlk Kinase Regulates A Retrograde Response To Axonal Injury, Xin Xiong, Xin Wang, Ronny Ewanek, Pavan Bhat, Aaron Diantonio, Catherine A. Collins Oct 2010

Protein Turnover Of The Wallenda/Dlk Kinase Regulates A Retrograde Response To Axonal Injury, Xin Xiong, Xin Wang, Ronny Ewanek, Pavan Bhat, Aaron Diantonio, Catherine A. Collins

Open Access Publications

No abstract provided.


Bjc Today Sep 2010

Bjc Today

BJC Today

No abstract provided.


Bjc Today Sep 2010

Bjc Today

BJC Today

No abstract provided.


School-Based Physical Activity And Fitness Promotion, Susan B. Racette, W. Todd Cade, Laura R. Beckmann Sep 2010

School-Based Physical Activity And Fitness Promotion, Susan B. Racette, W. Todd Cade, Laura R. Beckmann

Physical Therapy Faculty Publications

No abstract provided.


What's New In Spine Surgery, Keith H. Bridwell, Paul A. Anderson, Scott D. Boden, Alexander R. Vaccaro, Jeffrey C. Wang Aug 2010

What's New In Spine Surgery, Keith H. Bridwell, Paul A. Anderson, Scott D. Boden, Alexander R. Vaccaro, Jeffrey C. Wang

Open Access Publications

No abstract provided.


Age-Related Deterioration Of Rod Vision In Mice, Alexander V. Kolesnikov, Jie Fan, Rosalie K. Crouch, Vladimir J. Kefalov Aug 2010

Age-Related Deterioration Of Rod Vision In Mice, Alexander V. Kolesnikov, Jie Fan, Rosalie K. Crouch, Vladimir J. Kefalov

Open Access Publications

Even in healthy individuals, aging leads to deterioration in visual acuity, contrast sensitivity, visual field, and dark adaptation. Little is known about the neural mechanisms that drive the age-related changes of the retina and, more specifically, photoreceptors. According to one hypothesis, the age-related deterioration in rod function is due to the limited availability of 11-cis-retinal for rod pigment formation. To determine how aging affects rod photoreceptors and to test the retinoid-deficiency hypothesis, we compared the morphological and functional properties of rods of adult and aged B6D2F1/J mice. We found that the number of rods and the length of their outer …


W. Beaumont’S “On Physical Man Or The Phenomena Of Life Principally In Relation To Nutrition.” Undated Aug 2010

W. Beaumont’S “On Physical Man Or The Phenomena Of Life Principally In Relation To Nutrition.” Undated

Undated

No abstract provided.


W. Beaumont’S Notes From Works Of Jan Baptist Van Helmont Including “His Dream On The Flux Or Flowing Unto Generation” And “Prophetic Poems On Himself And His Works With An Acrostic On His Name.” Undated Aug 2010

W. Beaumont’S Notes From Works Of Jan Baptist Van Helmont Including “His Dream On The Flux Or Flowing Unto Generation” And “Prophetic Poems On Himself And His Works With An Acrostic On His Name.” Undated

Undated

No abstract provided.


Bjc Today Aug 2010

Bjc Today

BJC Today

No abstract provided.


Bjc Today Aug 2010

Bjc Today

BJC Today

No abstract provided.


Comparison Of Costs Of Surgical Site Infection And Endometritis After Cesarean Delivery Using Claims And Medical Record Data, Margaret A. Olsen, Anne M. Butler, Denise M. Willers, Gilad A. Gross, Victoria J. Fraser Aug 2010

Comparison Of Costs Of Surgical Site Infection And Endometritis After Cesarean Delivery Using Claims And Medical Record Data, Margaret A. Olsen, Anne M. Butler, Denise M. Willers, Gilad A. Gross, Victoria J. Fraser

Infectious Diseases Faculty Publications

No abstract provided.


Chronological List Of Events Of Beaumont’S Life From His Birth On November 21, 1785 To Doctor Joseph Lovell’S Death On October 17, 1836. Undated Jul 2010

Chronological List Of Events Of Beaumont’S Life From His Birth On November 21, 1785 To Doctor Joseph Lovell’S Death On October 17, 1836. Undated

Undated

No abstract provided.


Register Of Beaumont’S Correspondence Between September 1824 And May 15, 1852 With Synopses Of Each Letter. Undated Jul 2010

Register Of Beaumont’S Correspondence Between September 1824 And May 15, 1852 With Synopses Of Each Letter. Undated

Undated

No abstract provided.


Chronological List Of Events Of Beaumont’S Life From June 9, 1812–June 11, 1815, Including A Copy Of Beaumont’S Diary. Undated Jul 2010

Chronological List Of Events Of Beaumont’S Life From June 9, 1812–June 11, 1815, Including A Copy Of Beaumont’S Diary. Undated

Undated

No abstract provided.