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Articles 4981 - 5010 of 8116
Full-Text Articles in Entire DC Network
Skpa Restrains Synaptic Terminal Growth During Development And Promotes Axonal Degeneration Following Injury, E. J. Brace, Chunlai Wu, Vera Valakh, Aaron Diantonio
Skpa Restrains Synaptic Terminal Growth During Development And Promotes Axonal Degeneration Following Injury, E. J. Brace, Chunlai Wu, Vera Valakh, Aaron Diantonio
Open Access Publications
The Wallenda (Wnd)/dual leucine zipper kinase (DLK)-Jnk pathway is an evolutionarily conserved MAPK signaling pathway that functions during neuronal development and following axonal injury. Improper pathway activation causes defects in axonal guidance and synaptic growth, whereas loss-of-function mutations in pathway components impairs axonal regeneration and degeneration after injury. Regulation of this pathway is in part through the E3 ubiquitin ligase Highwire (Hiw), which targets Wnd/DLK for degradation to limit MAPK signaling. To explore mechanisms controlling Wnd/DLK signaling, we performed a large-scale genetic screen in Drosophila to identify negative regulators of the pathway. Here we describe the identification and characterization of …
Comparison Of Antibodies That Mediate Hiv Type 1 Gp120 Antibody-Dependent Cell-Mediated Cytotoxicity In Asymptomatic Hiv Type 1-Positive Men And Women, Mariana M. Mata, Joyce R. Iwema, Shanna Dell, Leslie Neems, Beth D. Jamieson, John Phair, Mardge H. Cohen, Kathryn Anastos, Linda L. Baum
Comparison Of Antibodies That Mediate Hiv Type 1 Gp120 Antibody-Dependent Cell-Mediated Cytotoxicity In Asymptomatic Hiv Type 1-Positive Men And Women, Mariana M. Mata, Joyce R. Iwema, Shanna Dell, Leslie Neems, Beth D. Jamieson, John Phair, Mardge H. Cohen, Kathryn Anastos, Linda L. Baum
Open Access Publications
No abstract provided.
Circadian Rhythm Reprogramming During Lung Inflammation, Jeffrey A. Haspel, Et Al
Circadian Rhythm Reprogramming During Lung Inflammation, Jeffrey A. Haspel, Et Al
Open Access Publications
No abstract provided.
Effects Of Instructions On Optokinetic Nystagmus (Okn), Erin Downs Whalen
Effects Of Instructions On Optokinetic Nystagmus (Okn), Erin Downs Whalen
Independent Studies and Capstones
The primary objective of this research study is to determine the effects of instructions on optokinetic nystagmus (OKN).
The Relationship Between Vulnerability To Temporary Versus Permanent Threshold Shifts In Balb, Cba/J And B6 Inbred Mice, Lauren Lewis
The Relationship Between Vulnerability To Temporary Versus Permanent Threshold Shifts In Balb, Cba/J And B6 Inbred Mice, Lauren Lewis
Independent Studies and Capstones
This study examines the dose-response relationship between TTS and PTS. Results indicate that susceptibility to TTS does not predict susceptibility to PTS and that long standing principles such as the equal energy hypothesis and early vulnerability period do not apply at low levels of noise.
Cognitive Consequences Of Degraded Speech: The Effect Of Background Noise, Noise-Vocoded Speech And Low-Pass Filtering On Short Story Recall, Laura Anne Horowitz
Cognitive Consequences Of Degraded Speech: The Effect Of Background Noise, Noise-Vocoded Speech And Low-Pass Filtering On Short Story Recall, Laura Anne Horowitz
Independent Studies and Capstones
Recall accuracy for speech-degraded short stories was assessed in young adults with normal hearing sensitivity. Stories were presented in the clear, or in noise vocoded, low-pass filtered, or background noise conditions of varying difficulty. Propositional scoring was used to determine the accuracy of participants’ recall. No significant effect on short story recall accuracy was observed for the degraded listening conditions. These results suggest that young adult listeners may be less susceptible to the extra cognitive challenge associated with degraded speech than might be predicted by the effortfulness hypothesis.
The Effect Of Anti-Inflammatory Drugs On Hair Cell Regeneration In The Zebrafish Lateral Line, Sarah C. Garbo
The Effect Of Anti-Inflammatory Drugs On Hair Cell Regeneration In The Zebrafish Lateral Line, Sarah C. Garbo
Independent Studies and Capstones
Hair cell death and regeneration on the three distal-most neuromasts in the posterior lateral line of zebrafish larvae were investigated after neomycin treatment. Treatment with ibuprofen, dexamethasone and salicylate examined the role of a normal inflammatory response on hair cell regeneration. Regeneration was observed 48 hours post-treatment indicating these reagents have no effect on the regeneration process.
The Early Language Environment And Effect Of Parental Counseling On Adult Language Exposure Of Children With Unilateral And Mild Bilateral Hearing Loss, Anita Marie Calwas
The Early Language Environment And Effect Of Parental Counseling On Adult Language Exposure Of Children With Unilateral And Mild Bilateral Hearing Loss, Anita Marie Calwas
Independent Studies and Capstones
This pilot study investigated the early language environment of children with unilateral and mild to moderate bilateral hearing loss. A one-time educational session with a parent is assessed for its ability to increase parental speech to children with unilateral and mild to moderate bilateral hearing loss.
Helminth.Net: Expansions To Nematode.Net And An Introduction To Trematode.Net., John Martin, Bruce A. Rosa, Philip Ozersky, Kymberlie Hallsworth-Pepin, Xu Zhang, Veena Bhonagiri-Palsikar, Rahul Tyagi, Qi Wang, Young-Jun Choi, Xin Gao, Samantha N. Mcnulty, Paul J. Brindley, Makedonka Mitreva
Helminth.Net: Expansions To Nematode.Net And An Introduction To Trematode.Net., John Martin, Bruce A. Rosa, Philip Ozersky, Kymberlie Hallsworth-Pepin, Xu Zhang, Veena Bhonagiri-Palsikar, Rahul Tyagi, Qi Wang, Young-Jun Choi, Xin Gao, Samantha N. Mcnulty, Paul J. Brindley, Makedonka Mitreva
Open Access Publications
No abstract provided.
The Transcription Factor Gtf2ird1 Regulates The Topology And Function Of Photoreceptors By Modulating Photoreceptor Gene Expression Across The Retina, Tomohiro Masuda, Xiaodong Zhang, Cindy Berlinicke, Jun Wan, Anitha Yerrabelli, Elizabeth A. Conner, Sten Kjellstrom, Ronald Bush, Snorri S. Thorgeirsson, Anand Swaroop, Shiming Chen, Donald J. Zack
The Transcription Factor Gtf2ird1 Regulates The Topology And Function Of Photoreceptors By Modulating Photoreceptor Gene Expression Across The Retina, Tomohiro Masuda, Xiaodong Zhang, Cindy Berlinicke, Jun Wan, Anitha Yerrabelli, Elizabeth A. Conner, Sten Kjellstrom, Ronald Bush, Snorri S. Thorgeirsson, Anand Swaroop, Shiming Chen, Donald J. Zack
Open Access Publications
No abstract provided.
Natural Antisense Transcripts Regulate The Neuronal Stress Response And Excitability, Xingguo Zheng, Vera Valakh, Aaron Diantonio, Yehuda Ben-Shahar
Natural Antisense Transcripts Regulate The Neuronal Stress Response And Excitability, Xingguo Zheng, Vera Valakh, Aaron Diantonio, Yehuda Ben-Shahar
Open Access Publications
No abstract provided.
Clonal Analysis Of Kit Ligand A Functional Expression Reveals Lineage-Specific Competence To Promote Melanocyte Rescue In The Mutant Regenerating Caudal Fin, Robert C. Tyron, Stephen L. Johnson
Clonal Analysis Of Kit Ligand A Functional Expression Reveals Lineage-Specific Competence To Promote Melanocyte Rescue In The Mutant Regenerating Caudal Fin, Robert C. Tyron, Stephen L. Johnson
Open Access Publications
No abstract provided.
Washington University School Of Medicine Bulletin, 2014-2015
Washington University School Of Medicine Bulletin, 2014-2015
Washington University School of Medicine Bulletins
No abstract provided.
Management Of Anticoagulant-Related Intracranial Hemorrhage: An Evidence-Based Review, Bappaditya Ray, Salah G. Keyrouz
Management Of Anticoagulant-Related Intracranial Hemorrhage: An Evidence-Based Review, Bappaditya Ray, Salah G. Keyrouz
Open Access Publications
No abstract provided.
Actin Scaffolding By Clathrin Heavy Chain Is Required For Skeletal Muscle Sarcomere Organization, Stéphane Vassilopoulos, Christel Gentil, Jeanne Lainé, Pierre-Olivier Buclez, Agathe Franck, Arnaud Ferry, Guillaume Précigout, Robyn Roth, John E. Heuser, Frances M. Brodsky, Luis Garcia, Gisèle Bonne, Thomas Voit, France Piétri-Rouxel, Marc Bitoun
Actin Scaffolding By Clathrin Heavy Chain Is Required For Skeletal Muscle Sarcomere Organization, Stéphane Vassilopoulos, Christel Gentil, Jeanne Lainé, Pierre-Olivier Buclez, Agathe Franck, Arnaud Ferry, Guillaume Précigout, Robyn Roth, John E. Heuser, Frances M. Brodsky, Luis Garcia, Gisèle Bonne, Thomas Voit, France Piétri-Rouxel, Marc Bitoun
Open Access Publications
No abstract provided.
Cortical–Subcortical Interactions In Hypersomnia Disorders: Mechanisms Underlying Cognitive And Behavioral Aspects Of The Sleep–Wake Cycle, Linda J. Larson-Prior, Yo-El Ju, James E. Galvin
Cortical–Subcortical Interactions In Hypersomnia Disorders: Mechanisms Underlying Cognitive And Behavioral Aspects Of The Sleep–Wake Cycle, Linda J. Larson-Prior, Yo-El Ju, James E. Galvin
Open Access Publications
No abstract provided.
Development Of The Hear Smart Card Sort Noise Assessment Program, Lana Marie Joseph
Development Of The Hear Smart Card Sort Noise Assessment Program, Lana Marie Joseph
Independent Studies and Capstones
The goal of this Capstone Project was to create a web-based application that would allow hearing practitioners to assess and counsel patients on the hazards of past and present occupational and recreational hazardous noise exposure.
Using Therapy Dogs To Improve Reading Fluency Of Children Who Are Deaf Or Hard Of Hearing: Is It Effective?, Jacklyn Marie Litzinger
Using Therapy Dogs To Improve Reading Fluency Of Children Who Are Deaf Or Hard Of Hearing: Is It Effective?, Jacklyn Marie Litzinger
Independent Studies and Capstones
The purpose of this paper is to discuss the effectiveness of using therapy dog reading programs with children who are deaf or hard of hearing using cochlear implants and hearing aids. It includes a literature review of reading fluency and therapy dog programs.
Progress In Research On Tourette Syndrome, Kevin J. Black, Joseph Jankovic, Tamara Hershey, Kevin St. P Mcnaught, Jonathan W. Mink, John Walkup
Progress In Research On Tourette Syndrome, Kevin J. Black, Joseph Jankovic, Tamara Hershey, Kevin St. P Mcnaught, Jonathan W. Mink, John Walkup
Psychiatry Faculty Publications
No abstract provided.
Reducing The Burden Of Acute Respiratory Distress Syndrome: The Case For Early Intervention And The Potential Role Of The Emergency Department, Brian M. Fuller, Nicholas M. Mohr, Richard Hotchkiss, Marin Kollef
Reducing The Burden Of Acute Respiratory Distress Syndrome: The Case For Early Intervention And The Potential Role Of The Emergency Department, Brian M. Fuller, Nicholas M. Mohr, Richard Hotchkiss, Marin Kollef
Emergency Medicine Faculty Publications
No abstract provided.
Renal Dysplasia, Halana V. Whitehead
Pathophysiology And Treatment Of Calcineurin Inhibitor Nephrotoxicity, Jonna Kemper, Kara Kniska
Pathophysiology And Treatment Of Calcineurin Inhibitor Nephrotoxicity, Jonna Kemper, Kara Kniska
Kidneycentric
No abstract provided.
Bacterial Nucleoid-Associated Protein Uncouples Transcription Levels From Transcription Timing, Igor Zwir, Won-Sik Yeo, Dongwoo Shin, Tammy Latifi, Henry Huang, Eduardo A. Groisman
Bacterial Nucleoid-Associated Protein Uncouples Transcription Levels From Transcription Timing, Igor Zwir, Won-Sik Yeo, Dongwoo Shin, Tammy Latifi, Henry Huang, Eduardo A. Groisman
Open Access Publications
No abstract provided.
A Statin-Loaded Reconstituted High-Density Lipoprotein Nanoparticle Inhibits Atherosclerotic Plaque Inflammation, Catherine Martel, Gwendalyn J. Randolph, Et Al
A Statin-Loaded Reconstituted High-Density Lipoprotein Nanoparticle Inhibits Atherosclerotic Plaque Inflammation, Catherine Martel, Gwendalyn J. Randolph, Et Al
Open Access Publications
No abstract provided.
Construction And Radiolabeling Of Adenovirus Variants That Incorporate Human Metallothionein Into Protein Ix For Analysis Of Biodistribution, David T. Curiel, Et Al
Construction And Radiolabeling Of Adenovirus Variants That Incorporate Human Metallothionein Into Protein Ix For Analysis Of Biodistribution, David T. Curiel, Et Al
Open Access Publications
No abstract provided.
Strategies To Prevent Clostridium Difficile Infections In Acute Care Hospitals: 2014 Update, Erik R. Dubberke, Philip Carling, Curtis J. Donskey, Vivian G. Loo, L. Clifford Mcdonald, Lisa L. Maragakis, Thomas J. Sandora, David J. Weber, Deborah S. Yokoe, Dale N. Gerding
Strategies To Prevent Clostridium Difficile Infections In Acute Care Hospitals: 2014 Update, Erik R. Dubberke, Philip Carling, Curtis J. Donskey, Vivian G. Loo, L. Clifford Mcdonald, Lisa L. Maragakis, Thomas J. Sandora, David J. Weber, Deborah S. Yokoe, Dale N. Gerding
Open Access Publications
No abstract provided.