Digital Commons Network^™

Tuberculosis In Jim Crow Virginia, 1900-1972, Elizabeth Dooley

Theses and Dissertations

Tuberculosis (TB) was a major public health concern in the United States, especially in the first half of the twentieth century. Transmission and treatment of the disease, which is spread between humans through close contact, was complicated by racial segregation laws in the South known as Jim Crow laws. Virginia subscribed to these laws, which played a role in how and where Black Virginians with TB could be treated. Segregated treatment facilities with an inadequate number of beds for the number of infected people and deaths in the state added to these complications of disease control and plan for eradication. …

Early Math Readiness And Later Achievement: A Longitudinal Study, Bailey Bontrager

Theses and Dissertations

The current body of literature provides much evidence that mathematics skills at the start of kindergarten are predictive of later mathematics achievement, and that students enrolled in early childhood education (ECE) programs are better prepared for mathematics at the start of kindergarten. However, the potential for children to develop mathematical skills prior to entering kindergarten relies on access to ECE programs and resources in families’ surrounding communities. Recent use of geospatial data collection techniques and measures of community resource availability have enabled researchers to examine specific localities for the ways in which community organizations and institutions support residents in particular …

Class-Aware Early-Exit Networks For Efficient And Secure Edge Deployment, Mohammed Ayyat

Theses and Dissertations

Edge devices increasingly run high-stakes machine learning workloads under strict latency, power, memory, and communication constraints. Deep neural networks provide the accuracy needed for tasks such as network intrusion detection, health monitoring, autonomous sensing, and human activity recognition, but conventional inference executes the same computational path for every input. Early-exit neural networks reduce average inference cost by allowing confident samples to terminate before the final layer. However, existing early-exit systems are largely class-agnostic: they allocate computation according to confidence or uncertainty, without considering that different output classes may carry different operational urgency. This dissertation develops class-aware early-exit inference, a framework …

Nanomagnet Based Straintronic Devices For Unconventional Computing: Simulation And Performance Analysis, Rahnuma Rahman

Theses and Dissertations

Nanomagnetic devices are of great interest in digital hardware because of their non-volatility and dynamic ability to change magnetization but suffer from high switching error rates and temperature sensitivity. Magnetostrictive nanomagnets that utilize strain to switch between stable magnetization states encoding bit information are of interest since they are extremely energy efficient as piezoelectric layers can be used to rotate magnetization that have switching energies in the range of attojoules. Their stochasticity can also be useful in probabilistic, analog, neuromorphic, and collective computing systems, where occasional switching errors are not devastating. The dissertation extends spintronics beyond conventional computing schemes by …

Discrete Cell Signaling Differences Cause Female-Dominant Il-33 Responses In Mast Cells, Tania D. Maldonado

Theses and Dissertations

Many allergic diseases are more common and severe in women than in men. A key component of allergic inflammation is IL-33, a cytokine released by epithelial cells after allergen exposure. Because mast cells are a central early responder in allergic disease and are activated by IL-33, we investigated sex differences in mast cell responses to IL-33. We first found that male mast cells expanded poorly in standard RPMI-based culture media containing phenol red, which has estrogenic properties. Male cells also responded poorly to IL-33 when cultured with in media containing phenol red. In contrast, female mast cells expanded 3-fold less …

Ontological Runtime Monitoring For Mission Engineering, Alexander R. Will

Theses and Dissertations

The advent of the Urban Air Mobility (UAM) concept will bring low-altitude aviation to civilians through passenger and cargo transport. However, the prospective vehicles in UAM studies are predominantly autonomous, raising questions about their efficacy and stability in densely populated urban areas. At the same time, extensive work has been performed to define a new branch of systems engineering that focuses on runtime behavior, synchronization, communication, and task allocation.This field is known as "mission engineering". Mission engineering has been deployed in military scenarios to model human-autonomy cooperation. By applying the concepts from this field to UAM, full systems-of-systems can be …

Real-Life Health Applications Of Wireless Sensing Using Edge Devices, Md Touhiduzzaman

Theses and Dissertations

Wireless sensing has emerged as a transformative paradigm that leverages ubiquitous radio-frequency signals for environmental perception and human activity recognition beyond their primary role in data communication. Unlike wearable sensors and camera-based systems, wireless sensing offers a non-intrusive, privacy-preserving, and cost-effective alternative that operates seamlessly under low-lighting conditions, through walls, and in non-line-of-sight (NLoS) scenarios. The growing availability of edge computing devices further enables real-time on-device data processing, making wireless sensing solutions highly suitable for in-home health monitoring and smart living applications. This dissertation investigates real-life health applications of wireless sensing through four completed systems, each addressing a distinct challenge …

Positive Body Image In Postpartum Women: A Psychometric Evaluation Of The Body Appreciation Scale-2 And A Phenomenological Exploration, Taylor Vashro

Theses and Dissertations

Postpartum women appear particularly vulnerable to body dissatisfaction due to the rapid physiological, emotional, and environmental changes that occur across the perinatal experience (Baskin et al., 2021; Nippert et al., 2021). Recent studies have demonstrated the experience of both negative and positive body image during postpartum (Rodgers et al., 2024; Watson et al., 2016). However, there is limited research regarding the measurement and exploration of positive body image in postpartum women. The current study aimed to: 1) evaluate the factor structure and psychometric properties of the Body Appreciation Scale-2 (BAS-2), a widely used measure of positive body image in postpartum …

The Development And Initial Validation Of A Measure Of Professional Mentoring Engagement Among School Counselors, Emily Kitching

Theses and Dissertations

This study describes the development and initial validation of the Mentoring Engagement Scale (MES), a self-report instrument designed to measure a person’s level of engagement in professional mentoring. Despite emerging evidence that professional mentoring may serve as a protective factor against the burnout and stress associated with school counselors’ roles and responsibilities, existing measures of mentoring are limited by weak documentation of development procedures, mixed psychometric support, and limited practical applicability. In two phases, the present study aimed to (1) evaluate content validity and systematically refine items grounded in Kahn’s (1990) theory of engagement and (2) investigate the preliminary psychometric …

The Long Shadow Of The Boys In Blue: Civil War Memory & The Evolution Of Veteran Identity In Twentieth Century Pennsylvania, Alexander L. Barbolish

Theses and Dissertations

This thesis presents a case study of the transformation of veteran identity and civic culture in Northeastern Pennsylvania, tracing the profound shifts in the way Americans remembered war, commemorated sacrifice, and defined what it meant to be a veteran, from the turn of the twentieth century to the dawn of World War II. By examining the complex interactions and relationships between three distinct and overlapping generations of veterans—those of the Civil War, the Spanish-American War, and World War I—this study argues that veteran identity was neither static nor monolithic, but was continually renegotiated through commemorative practice, organizational culture, and public …

A Framework For Digital Energy Modulation And Translation In Projectional X-Ray Imaging, Richard R. Wargo

Theses and Dissertations

In projectional X-ray imaging, acquisition energy fundamentally influences subject contrast, image noise, and radiation dose. While dual-energy techniques exploit spectral differences to optimize contrast and enable material separation, acquiring multiple images of the same anatomy often requires additional exposures and increased system complexity.

This dissertation presents a framework for digital energy modulation (DEM), in which computational models are trained to translate projection images between energy domains without requiring additional X-ray acquisitions. DEM is conceived as a generalizable strategy for controlled contrast modulation in projection imaging, with potential applications in image optimization, radiation therapy alignment, and dual-energy applications.

The framework was …

Medical Linear Accelerator Water Tank Measurements Optimization For Commissioning, Tyler R. Laugh

Theses and Dissertations

Beam commissioning is a critical component of linear accelerator (LINAC) implementation, requiring accurate measurement of percent depth dose (PDD), beam profiles, and output factors across a wide range of field sizes. Conventional commissioning workflows often require multiple detectors and can be time-intensive, particularly for small-field dosimetry where measurement accuracy is highly sensitive to detector characteristics. This study evaluated the performance of a plastic scintillation detector (BP-PSD) for full water tank commissioning and its potential to improve efficiency while maintaining dosimetric accuracy.

Beam data were acquired for field sizes ranging from 1 × 1 cm² to 40 × 40 cm² using …

Psychometric Evaluation Of The Treatment Integrity Instrument For Elementary School Classrooms - Observer Report: Preliminary Evidence For Construct And Discriminative Validity, Cristian J. Rivera Nales

Theses and Dissertations

Treatment integrity is the degree to which a program and its practices are delivered as intended. Treatment integrity measures are critical for evaluating the effectiveness of evidence-based programs (EBPs) in effectiveness research, but few are designed for research conducted in community settings, such as schools. The Treatment Integrity Instrument for Elementary School Classrooms – Observer Report (TIES-O) is an observational measure used to assess the treatment integrity of teachers implementing EBPs in their classrooms. This study evaluated the psychometric properties of the TIES-O, which captures Adherence (frequency and thoroughness of delivery) Competence (skillfulness of delivery), and Differentiation (the extent to …

Staging Violence With Intentionality, Toby O'Brien

Theses and Dissertations

This thesis examines the role of the fight choreographer in the theatre while addressing the potential issues staged violence has in distracting an audience from the intended narrative of the play. Avoiding the instruction manual approach of stage combat in favor of expounding on the theory of violent entertainment, I have constructed a thesis that informs the reader of certain types of violence found in both classical and modern productions and have researched the psychological ramifications of violent spectatorship and the necessity for content acknowledgements as well as consideration for the performer’s well-being. By exploring the history of violent entertainment …

Towards Sample-Efficient Deep Reinforcement Learning, Guang Yang

Theses and Dissertations

Deep reinforcement learning (DRL), combining reinforcement learning and high-performance function approximations such as deep neural networks (DNN), is a powerful approach to solving complex sequential decision-making problems. However, due to the complex solution space of the sequential decision-making problems and the inefficient design of the DRL algorithms, DRL algorithms usually require a prohibitively large number of data samples to train effective strategies. Consequently, it is difficult to apply these DRL algorithms to complex real-world problems that require high costs to collect a large volume of data samples. This dissertation proposes new mechanisms to address this sample inefficiency issue, realizing sample-efficient …

An Integrated Data-Driven Framework For Arctic Shipping: Analyzing Vessel Speed, Environmental And Ecological Factors Through Innovative Statistical Spatio-Temporal Methods, Inverse Optimization And Machine Learning, Mauli Pant

Theses and Dissertations

This dissertation develops an integrated data-driven framework to analyze vessel navigation and ecological risk in the United States Arctic from 2010 to 2019. As environmental change and maritime activity increase in the region, understanding how vessels respond to dynamic conditions and how those responses interact with marine ecosystems has become increasingly important. A central theme of this dissertation is the treatment of vessel speed as both an observed outcome and a decision variable reflecting trade- offs among operational, environmental, and ecological factors. The first chapter develops a predictive framework for vessel speed over ground (SOG) using Gaussian Process Boosting (GPBoost), …

Magnetic Resonance Only Planning Validation Using Synthetic Ct By Mvision, Eric D. Brass Sr

Theses and Dissertations

Problems: Adaptive radiotherapy requires clinically practical methods for responding to patient-anatomy changes that occur between the original planning images and the day of treatment delivery. Registering a previously acquired computed tomography scan to a newly acquired magnetic resonance image can introduce cross-modality uncertainty and may delay replanning. This thesis evaluates whether synthetic computed tomography generated from same-day magnetic resonance imaging can reduce registration-related uncertainty while supporting rapid dose recalculation for fraction-level adaptation.

Procedure: Magnetic resonance imaging DICOM data were exported from the ViewRay MRIdian treatment planning system and uploaded to MVision for synthetic computed tomography generation. The synthetic computed tomography …

The Ethereal Being That Is Me, And Maybe You, Hwiy Chang

Theses and Dissertations

The Ethereal Being That Is Me, and Maybe You is a 23-minute video collection of short stories accompanied by an installation at the Institute for Contemporary Art at Virginia Commonwealth University. This thesis explores the work’s creation as a visual and narrative meditation on self-transformation, drawing from personal experiences in therapy and philosophical texts including Carl Jung’s concept of the unconscious. The paper examines how each story represents a distinct stage of transformation—from recognizing patterns to confronting setbacks to reshaping internal dialogue—and how watercolor’s fluid, unpredictable nature serves as a visual metaphor for the process of change. The installation component …

Regulation Of Tgf-Β1–Induced Epithelial–Mesenchymal Transition By Integrin Inhibition, Wesam Elhawabri

Theses and Dissertations

Epithelial–mesenchymal transition (EMT) is a critical process underlying cancer progression, fibrosis, and tissue remodeling, characterized by coordinated changes in cell morphology, nuclear structure, and extracellular matrix (ECM) organization. Transforming growth factor beta 1 (TGF-β1) is a primary inducer of EMT; however, the extent to which integrin-mediated signaling and ECM remodeling regulate these structural changes remains incompletely understood. In this study, we quantitatively investigated EMT-associated remodeling in A549 lung carcinoma cells and MCF10A epithelial cells following TGF-β1 stimulation. Cells were cultured on ECM-coated substrates and treated with TGF-β1 in the presence or absence of integrin-targeting inhibitors (ATN-161, 28-G11, and STX-100). Im …

Absolute Quantification And Identification Of Rna From Rna-Lipid Nanoparticles Using High Resolution Mass Spectrometry, Jason C. Funderburk

Theses and Dissertations

RNA therapeutics are a rising drug category with potential use for a range of conditions encompassing infectious diseases to therapies for cancer, diseases, and genetic disorders. RNA-lipid nanoparticles (RNA-LNPs) are the prominent delivery method for these therapeutics approved products include mRNA vaccines and polyneuropathy treatments. The emergency use authorizations and orphan drug status of current RNA-LNP drugs has allowed approval without finalization of the regulatory analytical procedures for quality monitoring. The objective of the study was to develop an LC-MS assay to simultaneously measure identity and concentration of two therapeutically relevant intact RNA constructs extracted from RNA-LNPs to enhance quality …

Light And Unseen, Daša Kulikova

Theses and Dissertations

This thesis is a body of paintings and two poetic fragments. Shaped by distance and displacement, the work finds its ground in the tension between the desire to be free from the past and heal, and longing for home and connection. Painting practice becomes an event of contact with what is lost, or unclear, or in the process of becoming through accumulating layers, marks, erasures, and traces of the process of its making.

There Is A Puddle In Stonehenge, Nathaniel Newcomb

Theses and Dissertations

I began by making what I called "furniture": finding discarded logs and using a chainsaw, I milled out slabs of wood far larger than any normal board or beam, and gave them the function of chair, table, shelf. Sometimes it was a "shelf" in name only, and was commentary on furniture. In my practice, using discarded wood is necessary for the sake of the earth; making original pieces is necessary for the sake of my soul. I am reminded of megaliths when I erect these enormous forms in wood. I make intuitively, and like the meaning of megaliths, obscured by …

Film For Jeanette, Brice Goldberg

Theses and Dissertations

Film for Jeanette is an experimental documentary concerning grief, memory, and what remains of those who have left this physical plane. The film paints the portrait of my late sister, Jeanette Lee Goldberg, who died in a car accident when she was 19. What begins as a memorial becomes a celebration of her life and an exploration into the complexities of her character that led to her death. Jeanette’s story is told through interviews with family members, while the visuals, created with various alternative 16mm film techniques, depict my own journey through the filmmaking process. I was only 3 when …

All Other Ground Is Sinking Sand, Kevin Hopkins

Theses and Dissertations

My thesis project, All Other Ground Is Sinking Sand, is a body of work that frames soft sculpture as "prophetic charm" and collaborative performance as the ceremony that charges them. In this essay, I will explore the conceptual chronology of the charms, their connection to the notion of décalage, and their potential to compel witnesses toward the immediate liberation of queer, Black individuals.

With my research centered on the necessity of shifting cultural responses to enduring racial trauma, I focus my work on deconstructing Black hypermasculine archetypes shaped by white supremacy and unpacking the tension between individual autonomy and social …

Examining Mental Healthcare Underutilization Among Latino Immigrants: Healthcare Providers’ And Community Health Workers' Perspectives, Geovani Muñoz

Theses and Dissertations

Latinos continue to experience many logistical and systemic barriers to professional mental health services (Derr, 2016) despite being the second-largest racial-ethnic group in the United States (U.S.). With a community of 65 million people (U.S. Census Bureau, 2024), Latinos experience mental healthcare inequalities (Cook et al., 2019) due to structural, cultural, and systemic barriers. Although prior research has emphasized culturally responsive care as a pathway to reducing disparities (Nagy et al., 2025), much of the literature has focused on Western medical models, with limited attention to community-based perspective. Guided by the Knowledge, Attitude, and Practices (KAP) framework, the present study …

The Effects Of Overwash On Barrier Island Evolution And Building A Barrier Island Measure Of Resistance, Beth Thomas

Theses and Dissertations

Barrier islands are critical for coastal communities, as they serve as a natural buffer against storm surge, waves, and the effects of rising sea levels, protecting life and property. These islands continuously evolve due to both normal and severe environmental conditions; global warming makes it increasingly difficult to predict the evolution of these islands due to increases in storm frequency and intensity. We present a cellular model of barrier island evolution consisting of biotic and abiotic processes including the effects of vegetation, wind, ocean currents, and gravity. The model is used to predict the future evolution of barrier islands off …

Mathematical Models With Clinical Applications For Improving Health Outcomes, Helen Harris

Theses and Dissertations

In clinical settings, patients are exposed to many risks and stressors that could result in adverse health outcomes. Here we present mathematical models that seek to address these risks. First, we present a Markov Chain model to investigate the effect of medication reconciliation (MR) completion on patient health outcomes in the intensive care unit. Using this model, we simulate the annual incidence of adverse drug events (ADEs) for three different ADE rates. Based on the simulated results, we conduct a cost-benefit analysis for various levels of compliance to determine the financial implications of increasing MR completion depending on the baseline …

Algorhythm: Commodification Of Hobbies On Social Media Platforms, Fariha Ahmed

Theses and Dissertations

Forcing the world online, the COVID-19 pandemic appeared to turn social-media-based hobbies into income-generating cash cows. Digital creative spaces became sites of capitalist logic where hobbyists came to operate as both laborers and commodities. Profit-focused algorithms operate imperceptibly, shaping creative behavior and decision-making in ways that are difficult to recognize, and even harder to resist. This thesis asks how algorithmic participation on platforms such as Instagram conditions a hobbyist, and how that conditioning can be made legible to audiences who inhabit such platforms without always seeing them. Using autoethnography, I position myself as both researcher and subject to document the …

Dietary Acculturation, Dietary Inflammatory Potential, And Metabolic Syndrome Among Immigrants In The United States: A Mixed-Methods Approach Using Nhanes And Qualitative Data, Esse G. Foka Nzaha

Theses and Dissertations

Background and Objectives: Immigrants in the United States undergo acculturation — a process of sociocultural and behavioral adaptation to the host country. Increasingly, behavioral adaptations have been associated with cardiometabolic health and chronic disease risk. Metabolic syndrome (MetS), a cluster of conditions including abdominal obesity, elevated blood pressure, impaired fasting glucose, elevated triglycerides, and reduced HDL cholesterol, is a major risk factor for type 2 diabetes mellitus, cardiovascular diseases and other chronic diseases, including cancer. Despite the growing immigrant population in the U.S., the role of diet and dietary acculturation in MetS development remains poorly understood in this population. This …

Mediator: Ornament As A Visual Language Of The Transcendent, Selma Fejzullaj

Theses and Dissertations

Adolf Loos’s declaration that “ornament is a crime” defined modernist design, establishing a legacy that dismisses ornamentation as wasteful and regressive. This research questions that legacy by repositioning aesthetics as a divinely grounded value, inspired by the Qur’anic vision of Paradise. In this celestial realm, beauty is not wasteful but a manifestation of divine perfection. Conceptually, the project reclaims ornament as a vital tool for contemplating metaphysical themes. Materially, it reimagines glass, shifting it from modernist "radical honesty" to a medium of layered depth. Recombining traditional Islamic ornamentation practices such as Girih and Chaharbagh, the project evokes the Qur’anic vision …