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Articles 5101 - 5130 of 7363
Full-Text Articles in Entire DC Network
Bioinformatic Analysis Of A Mammalian Bip Gene For Insertion Into Green Algae And Comparison Of Its Possible Effects On The Synthesis Of A Mammalian Antibody, Katrina Ghazanfar
Bioinformatic Analysis Of A Mammalian Bip Gene For Insertion Into Green Algae And Comparison Of Its Possible Effects On The Synthesis Of A Mammalian Antibody, Katrina Ghazanfar
Theses and Dissertations
This dissertation describes a study utilizing bioinformatics to analyze homologues of a molecular chaperone, glucose-regulated protein 78 (grp 78), also known as BiP. The selected homologous proteins originate from organisms of infinitely diverse genera. Comparisons of protein sequence yielded the first clues of a common ancestry among these proteins. Furthermore, protein molecular weights, isoelectric points, N-terminal amino acids and half-lives of a known homolog and a non-homologous protein were examined. Additionally, electroporation, a state-of-the-art plasmid insertion technique, was explored using Chlamydomonas reinhardtii, a green alga, as the recipient of a parent plasmid, pSP124S. Distinctive hypertonic solutions and three separate field …
The Scarab (2004-06)
The Scarab, 1952-2010
From the cover: "Official Organ of the Alumni Association of the Medical College of Virginia."
Shafer Court Connections (2004-06)
Shafer Court Connections (2004-06)
Shafer Court Connections, 1994-2010
For alumni of the Academic Campus of Virginia Commonwealth University.
Moderate Mutation Rate In The Sars Coronavirus Genome And Its Implications, Zhongming Zhao, Haipeng Li, Xiaozhuang Wu, Yixi Zhong, Keqin Zhang, Ya-Ping Zhang, Eric Boerwinkle, Yun-Xin Fu
Moderate Mutation Rate In The Sars Coronavirus Genome And Its Implications, Zhongming Zhao, Haipeng Li, Xiaozhuang Wu, Yixi Zhong, Keqin Zhang, Ya-Ping Zhang, Eric Boerwinkle, Yun-Xin Fu
Psychiatry Publications
Background The outbreak of severe acute respiratory syndrome (SARS) caused a severe global epidemic in 2003 which led to hundreds of deaths and many thousands of hospitalizations. The virus causing SARS was identified as a novel coronavirus (SARS-CoV) and multiple genomic sequences have been revealed since mid-April, 2003. After a quiet summer and fall in 2003, the newly emerged SARS cases in Asia, particularly the latest cases in China, are reinforcing a wide-spread belief that the SARS epidemic would strike back. With the understanding that SARS-CoV might be with humans for years to come, knowledge of the evolutionary mechanism of …
Calcium And Glycolysis Mediate Multiple Bursting Modes In Pancreatic Islets, Richard Bertram, Leslie S. Satin, Min Zhang, Paul Smolen, Arthur Sherman
Calcium And Glycolysis Mediate Multiple Bursting Modes In Pancreatic Islets, Richard Bertram, Leslie S. Satin, Min Zhang, Paul Smolen, Arthur Sherman
Pharmacology and Toxicology Publications
Abstract
Pancreatic islets of Langerhans produce bursts of electrical activity when exposed to stimulatory glucose levels. These bursts often have a regular repeating pattern, with a period of 10–60 s. In some cases, however, the bursts are episodic, clustered into bursts of bursts, which we call compound bursting. Consistent with this are recordings of free Ca2+ concentration, oxygen consumption, mitochondrial membrane potential, and intraislet glucose levels that exhibit very slow oscillations, with faster oscillations superimposed. We describe a new mathematical model of the pancreatic β-cell that can account for these multimodal patterns. The model includes the feedback of …
Competition Between Linear And Cyclic Structures In Monochromium Carbide Clusters Crcn- And Crcn (N=2-8): A Photoelectron Spectroscopy And Density Functional Study, Hua-Jin Zhai, Lai-Sheng Wang, P. Jena, G. L. Gutsev, C. W. Bauschlicher Jr.
Competition Between Linear And Cyclic Structures In Monochromium Carbide Clusters Crcn- And Crcn (N=2-8): A Photoelectron Spectroscopy And Density Functional Study, Hua-Jin Zhai, Lai-Sheng Wang, P. Jena, G. L. Gutsev, C. W. Bauschlicher Jr.
Physics Publications
Photoelectron spectroscopy (PES) is combined with density functional theory (DFT) to study the monochromium carbide clusters CrC−n and CrCn (n=2–8). Well-resolved PES spectra were obtained, yielding structural, electronic, and vibrational information about both the anionic and neutral clusters. Experimental evidence was observed for the coexistence of two isomers for CrC−2, CrC−3, CrC−4, and CrC−6. Sharp and well-resolved PES spectra were observed for CrC−n (n=4,6,8), whereas broad spectra were observed for CrC−5 and CrC−7. Extensive DFT calculations using the generalized gradient approximation were carried out for the ground and low-lying excited states of all the CrC−n and CrCn species, as well …
Virginia Commonwealth University Fall Commencement Program [2004], Virginia Commonwealth University
Virginia Commonwealth University Fall Commencement Program [2004], Virginia Commonwealth University
VCU Commencement Programs
No abstract provided.
A Review Of The Physiological And Immunological Functions Of Biliary Epithelial Cells: Targets For Primary Biliary Cirrhosis, Primary Sclerosing Cholangitis And Drug-Induced Ductopenias, Chih-Te Wu, Paul A. Davis, Vellmir A. Luketic, M. Eric Gershwin
A Review Of The Physiological And Immunological Functions Of Biliary Epithelial Cells: Targets For Primary Biliary Cirrhosis, Primary Sclerosing Cholangitis And Drug-Induced Ductopenias, Chih-Te Wu, Paul A. Davis, Vellmir A. Luketic, M. Eric Gershwin
Internal Medicine Publications
Our understanding of biliary epithelial cells (BEC) in physiobiology and immunology has steadily expanded. BEC transports IgA as well as IgM into bile, synthesizes and secretes various chemokines, cytokines, and expresses adhesion molecules involved in cell interaction and signal transduction. These then suggest a myriad of potential roles for BEC in defense from invading microorganisms as well as the pathogenesis of diverse immunologically driven diseases such as primary biliary cirrhosis (PBC), graft-versus-host disease, and primary sclerosing cholangitis (PSC). Despite the progress, there still remain many areas of BEC biology that require further investigation. Most importantly, it remains to be clarified …
Palifermin For Oral Mucositis After Intensive Therapy For Hematologic Cancers, Ricardo Spielberger, Patrick Stiff, William Bensinger, Teresa Gentile, Daniel Weisdorf, Tarun Kewalramani, Thomas Shea, Saul Yanovich, Keith Hansen, Stephen Noga, John Mccarty, C. Frederick Lemaistre, Eric C. Sung, Bruce R. Blazar, Dieter Elhardt, Mon-Gy Chen, Christos Emmanouilides
Palifermin For Oral Mucositis After Intensive Therapy For Hematologic Cancers, Ricardo Spielberger, Patrick Stiff, William Bensinger, Teresa Gentile, Daniel Weisdorf, Tarun Kewalramani, Thomas Shea, Saul Yanovich, Keith Hansen, Stephen Noga, John Mccarty, C. Frederick Lemaistre, Eric C. Sung, Bruce R. Blazar, Dieter Elhardt, Mon-Gy Chen, Christos Emmanouilides
Internal Medicine Publications
BACKGROUND: Oral mucositis is a complication of intensive chemotherapy and radiotherapy with no effective treatment. We tested the ability of palifermin (recombinant human keratinocyte growth factor) to decrease oral mucosal injury induced by cytotoxic therapy. METHODS: This double-blind study compared the effect of palifermin with that of a placebo on the development of oral mucositis in 212 patients with hematologic cancers; 106 patients received palifermin (60 microg per kilogram of body weight per day) and 106 received a placebo intravenously for three consecutive days immediately before the initiation of conditioning therapy (fractionated total-body irradiation plus high-dose chemotherapy) and after autologous …
The Effect Of Loading On Disturbance Sounds Of The Atlantic Croaker Micropogonius Undulatus: Air Versus Water, Michael L. Fine, Justin Schrinel, Timothy M. Cameron
The Effect Of Loading On Disturbance Sounds Of The Atlantic Croaker Micropogonius Undulatus: Air Versus Water, Michael L. Fine, Justin Schrinel, Timothy M. Cameron
Biology Publications
Physiological work on fish sound production may require exposure of the swimbladder to air, which will change its loading (radiation mass and resistance) and could affect parameters of emitted sounds. This issue was examined in Atlantic croaker Micropogonius chromis by recording sounds from the same individuals in air and water. Although sonograms appear relatively similar in both cases, pulse duration is longer because of decreased damping, and sharpness of tuning (Q factor) is higher in water. However, pulse repetition rate and dominant frequency are unaffected. With appropriate caution it is suggested that sounds recorded in air can provide a useful …
Virginia Commonwealth University Commencement Program [2004], Virginia Commonwealth University
Virginia Commonwealth University Commencement Program [2004], Virginia Commonwealth University
VCU Commencement Programs
No abstract provided.
Virginia Commonwealth University Graduate And Professional Programs Bulletin [2004], Virginia Commonwealth University
Virginia Commonwealth University Graduate And Professional Programs Bulletin [2004], Virginia Commonwealth University
VCU Bulletins
Graduate and professional programs bulletin for Virginia Commonwealth University for the academic year 2004-2005. It includes information on academic regulations, degree requirements, course offerings, faculty, academic calendar, and tuition and expenses for graduate programs.