Association Of Interpersonal Trauma And Polygenic Risk Scores With Depressive Symptoms In College Students, Rowan K. O'Hara

Theses and Dissertations

Major depression is considered a complex trait influenced by both polygenic risk factors and environmental exposures, such as childhood trauma. This study applied statistical genetic methods to calculate aggregate genetic risk for major depression to predict depressive symptoms scores in a college student sample. Data were from the Spit for Science (S4S) study in which college students from a large urban university self-reported interpersonal trauma (IPT) exposure prior to college and depressive symptoms from the past month (N = 7502; ancestry group: 20% African [AFR], 12% Admixed Americas [AMR], 10% East Asian [EAS], 49% European [EUR], 8% South Asian [SAS]). …

Exploring Polyamorous Relationship Experiences Of Lesbian, Gay, Bisexual, And Pansexual Individuals, Jiale Man

Theses and Dissertations

Polyamory is a type of relationship under the consensual non-monogamy relationship umbrella that assumes the possibility, validity, and worthwhileness of maintaining romantic, sexual, and intimate relationships with multiple people simultaneously. In Western society, the prevalence and domination of mononormativity have led to the marginalization of relationships alternative to monogamy (i.e., polyamory). As a result, individuals in polyamorous relationships continue to experience bias, stigma, and discrimination at varying levels. With a rise in public interest in CNM in the past two decades, scientists and researchers have slowly started to examine various topics related to CNM, including its prevalence, public attitudes toward …

Coming Out To Treatment: Identifying Facilitators & Characterizing Experiences Of Sexual And Gender Minoritized Individuals In Opioid Use Disorder Treatment Before And During The Covid-19 Pandemic, Jaclyn S. Sadicario

Theses and Dissertations

Sexual and Gender Minority (SGM) individuals are disproportionately impacted by substance use disorders vs. their non-SGM counterparts. Additionally, SGM folks face more barriers to access for treatment than others due to minority stressors including discrimination, internalized stigma, and marginalization related to their sex and gender minority statuses. It is important for researchers and treating providers alike to understand how these different factors are impacting the treatment of substance use disorders in SGM populations. With this in mind, this two phase study employed a mixed-methods approach to (1) describe the population of SGM folks enrolled in a MOUD treatment program with …

“It's Just Not Enough”: Examining The Experiences Of School-Based Sexual Health Education And Conversation Engagement With Trusted Adults Among Black Boys In Richmond, Va, Sharyn A. Dougherty

Theses and Dissertations

The Centers for Disease Control and Prevention estimate that youth make up a quarter of the sexually active population, yet account for half of the 20 million new sexually transmitted infections in the United States.In 2021, youth age 15-19 living in Virginia’s central region, which includes the Richmond Metropolitan area, had the second highest number of chlamydia cases and fourth highest number of gonorrhea cases among all age groups, with the highest rates among Black youth. The aim of this study is to explore the experiences of Black youth in Richmond, VA with school-based sexual health education (SHE) and their …

Recovery Sleepers: A Pilot Study Of A Sleep Health Intervention For College Students In Recovery From Substance Use Disorder, Morgan P. Reid

Theses and Dissertations

There is an increasing number of students in recovery from substance use disorder (SUD) on college campuses, and collegiate recovery programs have been designed to support students’ recovery and global health needs. However, little research has focused on interventions that can promote health outcomes within this population. Chronic substance misuse can have lingering, negative effects on sleep even after sustained remission; thus, the present paper describes a pilot study of Recovery Sleepers, a sleep health promotion intervention rooted in self-determination theory for college students in recovery from SUD. Study aims were to examine the feasibility, acceptability, and fidelity of the …

The Effect Of Strain And Drug Combinations On Ketamine's Locomotor Activating Effects In Rats, Caroline K. Flagler

Theses and Dissertations

Rationale: Initially developed as an anesthetic, ketamine is now used to treat a variety of disorders, including treatment resistant depression (TRD). While ketamine appears to be a breakthrough therapy for TRD, it has many use-limiting side effects, including abuse liability, psychotomimetic effects, and sedation. Utilizing ketamine in combination with other medications, such as the monoaminergic antidepressant desipramine (DSP), opioid antagonist naltrexone (NTX), and the NMDA receptor partial agonist D-cycloserine (DCS) may reduce side-effects resulting from ketamine therapy.

Objectives: The goal of this project was to study ketamine’s adverse effects using locomotor activation in an open field as a behavioral correlate …

Well-Being From Home To Work: The Role Of Mindfulness, Alisha Gupta

Theses and Dissertations

Considering the growing spillover of work and home and its impact on well-being, I draw from the Work-Home Resources Model and Attention Restoration Theory to examine the effects of evening recovery experiences at home on mindfulness at work and eudaimonic workplace well-being. Specifically, I focus on two indicators of eudaimonic well-being—one indicator of psychological functioning (work meaningfulness) and one indicator of social functioning (high-quality connections; HQCs). Further, I introduce a boundary condition, distance from work, of the relationship between evening recovery experiences and mindfulness. I suggest that due to alternative work arrangements in today’s workforce (i.e., that permit increased overlap …

Quantitative And Molecular Genetic Analyses Of Brain Structure, Substance Use, And Posttraumatic Stress Phenotypes: Data From Children, Adolescents And Adults, Daniel Bustamante

Theses and Dissertations

Abstract

QUANTITATIVE AND MOLECULAR GENETIC ANALYSES OF BRAIN-IMAGING, SUBSTANCE USE, AND POSTTRAUMATIC STRESS PHENOTYPES: DATA FROM CHILDREN, ADOLESCENTS AND ADULTS

By Daniel Bustamante, B.S., B.A.

Doctoral dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy in Integrative Life Sciences – Behavioral and Statistical Genetics at Virginia Commonwealth University.

Virginia Commonwealth University, 2023.

Dissertation directors: Michael C. Neale, Ph.D., Banks Distinguished Professor of Psychiatry & Human and Molecular Genetics; and, Ananda B. Amstadter, Ph.D., Professor of Psychiatry, Psychology, & Human and Molecular Genetics.

Substance use (SU) and posttraumatic stress disorder (PTSD) phenotypes are comorbid, share …

I'M Not Sure It Was A Hoopoe Or A Decanter, Ali Kaeini

Theses and Dissertations

“I’m not sure it was a Hoopoe or a Decanter” explores the experience of cultural displacement through the lens of an Iranian artist and immigrant. Drawing on ancient Iranian stories, Persian poetry, and cultural artifacts, my paintings and drawings reflect the uncertainty of the contemporary political and religious conditions in Iran, as well as the challenges faced by individuals forced to flee their homeland due to war, political instability, and social conditions. My work weaves references to ancient Iranian objects, Persian miniatures' structural forms and patterns, and Islamic architecture, using traditional and contemporary materials to create large, unconventional paintings. Through …

Examining The Home Interventionist Model Of Care In Pediatric Asthma, Katherine D. Lohr

Theses and Dissertations

Pediatric asthma disproportionately affects children living in urban areas and within families reporting an income below the poverty threshold. Home interventionist models of care, utilizing interventionists from the communities they serve, have been found to improve pediatric asthma symptoms and reduce Medicaid costs. Home interventionists, such as community health workers (CHWs) and Healthy Homes assessors (HHAs), focus on connecting care among schools, providers, and homes, and empowering families in accessing resources to overcome barriers to care. However, research is just beginning to understand how home interventionists create positive change among families within low-income, urban communities. This dissertation study used a …

Buckets In A Deep Well: Essays About Shakespeare’S History Play Characters And An Original Drama, Brian C. Bassett

Theses and Dissertations

Buckets in a Deep Well is a set of essays that examines various characters portrayed in Shakespeare’s history plays, as well as parallel figures in 20th and 21st century works. Each essay primarily focuses on a single character’s response to a power structure: Richard Gloucester to the Tudor England of his audience in Richard III; Richard Nixon’s campaign-produced version of himself to 20th century American democracy in “Checkers;” Falstaff to organized society in Henry IV, Part 1; Marlo Stanfield to the drug economy of early 2000’s Baltimore in The Wire; the Duke of York to the disrupted monarchy of The …

Risk And Resilience: An Exploration Of Adverse Childhood Experiences, Protective Factors, And Internalizing Symptoms In Black Youth, Irene A. Jacobs

Theses and Dissertations

The study examines mechanisms of risk and resilience that influence the psychological well-being of Black youth. Previous literature has established a link between adverse childhood experiences (ACEs) and mental health outcomes in youth (Kerker et al., 2015; Thakur et al., 2020). A substantial amount of the ACEs literature solely focuses on risk factors (e.g., mental impairment, low SES, health risk behaviors) for poor outcomes associated with ACEs. Despite Black youth experiencing high rates of ACEs (Liu et al., 2019), the ACEs literature examining mechanisms of their resilience is sparse (Meeker et al., 2021). Given the state of the ACEs literature, …

Sustaining Breaths For Restorative Rest: A Preliminary Evaluation Of Sleep, Mental Health, And Cognitive Function Following Hypoglossal Nerve Stimulation For Obstructive Sleep Apnea, Elliottnell Perez

Theses and Dissertations

Introduction: Obstructive sleep apnea (OSA) is a sleep-related breathing disorder that produces repetitive obstruction or collapse of the upper airway. Positive airway pressure (PAP) therapy is the gold standard treatment for OSA. Hypoglossal nerve stimulation (HNS) is considered an alternative treatment for patients who are unable to tolerate PAP therapy. The purpose of the study was to examine sleep, mental health, and cognitive health outcomes before and after HNS to determine its viability as an alternative treatment.

Methods: The study utilized a single-group, pretest-posttest design. Objective and subjective sleep was measured using actigraphy, sleep diary, and questionnaires. Objective and subjective …

Community On Campus: Examining The Impact Of Campus Climate, Belonging, And Flourishing On Bystander Behavior Among Diverse University Students, Amelia Liadis

Theses and Dissertations

This exploratory, nonexperimental study aimed to investigate the relationships among diverse undergraduate and graduate students’ perceived campus climate, flourishing, and university belonging on bystander intentions and bystander behaviors during the COVID-19 pandemic. The study’s theoretical framework combined the Theory of Planned Behavior and feminist theory, and examined intersectionality through an Identity Risk Index. Data used in the current study were originally collected as part of an institutional Healthy Minds Survey, on health behaviors of college students; responses from n = 171 of the randomly selected participants were used in the current study’s analyses. The majority of participants indicated at least …

The Promis Women Education Program: Promoting Cervical Cancer Prevention Methods Among Muslim Women In Virginia, Asmaa M. Namoos

Theses and Dissertations

Abstract

Purpose: US Muslim women have suboptimal participation in cervical cancer screening and prevention services. This is due in part to a lack of access to culturally relevant education programs. To address this issue three aims were identified: Aim 1. Adapt existing evidence- based educational materials for a religious and culturally appropriate intervention; Aim 2. Test the preliminary efficacy of the intervention and Aim 3. Assess the feasibility and acceptability of the intervention and materials.

Methods: The ORBIT model for developing behavioral interventions guided intervention design, refinement (Phase I), and preliminary testing (Phase II). Focus groups and interviews were conducted …

Incorporating Noh Training Into Contemporary Western Theatre: An Examination Of The Benefits To Implementing Noh Theatre And Suzuki Training Into Western Performance Pedagogy, Baylee A. Holloran

Theses and Dissertations

Noh theatre is a traditional Japanese theatre practice that focuses on isolated and intentional physicality and separating actor personality from character. It is an imaginative and heightened performance that differs greatly from Western theatrical realism. This thesis examines Noh theatre, its origins, and why it should be more implemented into Western acting pedagogy. I start by describing what Noh is as an art form, from the ritualistic aspects to how it is staged and performed. Then I outline the religious and historical significance of Noh and how they are showcased in its storytelling and performance. I analyze the pedagogies of …

Illusion: Immersive Experience, Tessa S. Trowbridge

Theses and Dissertations

Can society learn from art, and if so, what type of knowledge can be gained from art? It is currently understood that art and design can help humans explore, discover, and understand philosophical and imaginative topics. There is a general agreement that art can create insight and awareness in ways that logical and rational statements cannot, and from these unique interactions, humans can see the world with a new perspective (Worth, n.d.). This thesis will investigate the claim that art can inspire human imagination and allow viewers to gain insight into a surreal reality using designed, physically immersive spaces.

Immersive …

Underrepresentation Of Black Participants In Drug Court: Reasons Reported For Non-Admission In Six Jurisdictions, Kathryn J. Genthon

Theses and Dissertations

Despite the beneficial impacts of drug court participation, access to these programs may not be equitable across racial groups. The reasons behind racial disparities in access to these programs are not well-documented in the current literature. This study investigates disparities in access to drug court and the possible reasons they occur. Chi-square tests are used to assess for disparities in admissions between Black and White individuals referred to drug court. Additional statistical analyses addressed the association of sex and age with admission to provide a broader picture of the impact of a variety of demographic characteristics on admission to drug …

Sense Of Belonging As Behaviorist Construct: “Doing Belonging” And Its Application For College Students With Disabilities, Chris Parthemos Phd

Theses and Dissertations

Sense of Belonging has been widely linked to academic performance, retention and persistence for college students. Students with disabilities are less likely to enroll than peers, and are more likely to drop out. Similar to other historically-marginalized groups, these students report lower sense of belonging than peers. Research with this population suggests that they may be seeking ways of building community and belonging at their universities which are self-driven. This notion of “doing belonging”, as it is described in the sociological literature, appears at first glance to be compatible with behaviorist approaches to student support. Although not without controversy, behavior …

Activity Levels Of Different Cell Types In An Epileptogenic Model Of Cortical Microgyria: A Cfos Investigation, Peter F. Lamothe

Theses and Dissertations

A large percentage of individuals with intractable epilepsies have an accompanying cortical malformation, the underlying cellular mechanisms of which are not fully understood. In an animal model for one such malformation, polymicrogyria, epileptogenesis occurs most easily in a region of tissue just adjacent to the microgyria termed the paramicrogyral region (PMR). Previous studies implicate somatostatin containing interneurons (SOM) as a potential contributor to this pathology, and show increased excitation of SOM in the PMR. We hypothesis that SOM are more active in the PMR when compared to SOM within the homologous region of the control cortex. In addition to this …

Incorporating A Developmental Perspective Into Gene Identification Models For Alcohol Use Behaviors, Nathaniel S. Thomas

Theses and Dissertations

Frequent alcohol use can lead to alcohol use disorder, which accounts for three million deaths and over 133 million life years lost to disability and death worldwide per year. Alcohol use behaviors unfold across development, beginning with initiation of drinking and progressing through various escalating stages of use. Alcohol use behaviors are also under genetic influence. Genome-wide association represents the state-of-the-science statistical methodology for identifying genes associated with alcohol use outcomes. However, contemporary genome-wide association study (GWAS) methods typically do not account for variability in genetic effects throughout development. In this project, I applied novel multivariate genomic methods to combine …

Exploring The Effect Of Early Motor Delay And Physical Therapy Interventions On The Parent-Child Relationship, Rebecca Molinini

Theses and Dissertations

Emotional availability (EA) or the ability of the parent-child dyad to engage emotionally and partake in congruent and mutually enjoyable interactions, is essential for familial health and well-being. EA is considered the “connective tissue” of healthy parent-child relationships and is associated with secure attachment, maternal mental health, and children’s adaptive development. Most evidence supporting the integral role of EA on healthy outcomes is supported by typically developing populations in which adults present with a social or biological risk factor such as experiencing past traumas of adversities with mental health. In line with the transactional model of development, children are equal …

Examining Psychosocial Factors Of Chronic Disease Control To Improve Outcomes For Patients With Multiple Chronic Conditions, Kristen O'Loughlin

Theses and Dissertations

Psychosocial needs are associated with worse health outcomes for patients with multiple chronic conditions (MCC). The Biopsychosocial Model provides a framework for conceptualizing the influence that psychosocial factors have on the management of disease. To date, research has primarily focused on examining the relation between psychosocial factors and chronic disease onset. Therefore, the temporal relation between psychosocial factors and disease management remains poorly understood. The current study aimed to 1) describe patients’ psychosocial needs and their prioritization, 2) examine reciprocal relations between anxious symptoms, depressive symptoms, social needs, and MCC management, and 3) qualitatively explore patient definitions of health in …

Amtrak Staples Mill Station: Strategic Vision Plan 2023, Daniel S. Longest

Master of Urban and Regional Planning Capstone Projects

This plan proposes the replacement of the current Amtrak Staples Mill Station with a new facility designed to incorporate civic art, multi-use development, and fast and easy train boarding. Drawing on successful examples like Union Station in D.C. and Main Street Station in Richmond, this plan encourages stakeholders to adopt a strategic vision for the station and its vicinity as an asset to the region. An independent commission with equal representation from state agency representatives and residents would enact these improvements through a public-private partnership, including a transit-oriented development scheme for adjacent land.

Putting The “U” In Shore U: Expanding Postsecondary Education On Virginia’S Eastern Shore, Katelyn D. Jones, Karen Belanger, Katharine Wise, Takeya Mclaurin

Doctor of Education Capstones

The University of the Eastern Shore of Virginia Foundation (Shore U) submitted a Request for Assistance to examine opportunities to expand postsecondary education on Virginia’s Eastern Shore. In response to this request, a doctoral research team conducted a mixed-methods study that explored potential pathways for a four-year degree option on the Eastern Shore. Eastern Shore Community College (ESCC) students, ESCC employees, and Eastern Shore community members were surveyed during the quantitative phase of the study. Secondary data was used to understand the postsecondary positionality of Eastern Shore high school students. The President of ESCC, Eastern Shore community members, and Virginia …

Assessing Graduate Student Needs And Structures Of Support At Virginia Commonwealth University, Trisha Saunders, Kiama Anthony Bishop, Herbert Hill Iii, Tameka Fitzgerald Burroughs

Doctor of Education Capstones

The purpose of this multi-case study was to explore how the institutional landscape is designed to support graduate student success at Virginia Commonwealth University (VCU), a large, public, urban, R1 research university. The study included review of existing literature on the various factors that contribute to or limit graduate student success at institutions across the country. A major aim of this study was to collect qualitative data from participants with a key stake in this issue, including enrolled graduate students, and faculty/staff supporting graduate (master’s and doctoral) programs at VCU. Participants included 39 graduate students and 23 institutional stakeholders. All …

A Brighter Future For Sms: Cultivating School Coherence Through A Shared Vision, Nicole K. Herndon, Heather Holcomb, Audra Krupp

Doctor of Education Capstones

Staunton City Public Schools submitted an RFA (Request for Assistance) to Virginia Commonwealth University (VCU) to address concerns at Shelburne Middle School related to teacher satisfaction, student discipline, and student achievement. Document and data analysis, a site visit, and partner interviews surfaced issues of organizational fragmentation; the capstone team identified the need for a collaboratively constructed and implemented vision to better cohere the school. Through document analysis and stakeholder surveys, our mixed methods study aimed to understand stakeholder views on three aspects to support the work of the leadership team at SMS. First, the capstone team identified the needs in …

A Case Study Exploring William & Mary Military Alums' Experiences With Career Transition, Dirron Allen, Amanda Baldwin-Estep, Matthew Grinsell, Kimberly Lintag-Nguyen

Doctor of Education Capstones

Background: The purpose of this qualitative study was to understand William & Mary (W&M) Master of Business Administration (MBA) military alums’ experiences with their career transitions post-graduation and the influence of the program on their experiences.

Methods: This study utilized a case study design, including focus groups and interviews with 21 alums from the last 10 years and formal, semi-structured interviews with six current faculty and staff. We used Schlossberg’s (1981) individuals’ situation, self, support, and strategies to analyze data using thematic analysis, and then iteratively reducing codes into themes.

Results: Demographic findings showed a lack of diversity, such as …

Unmet: The Undergraduate Experience Of Basic Need Insecurity At An Uncommon University, Michelle C. Bair, Rachelle V. Blackwell-Stegall, Sara E. Rafuse, Ra’Meer J. Roberts, Sara E. Weinstein

Doctor of Education Capstones

Virginia Commonwealth University’s (VCU) Dean of Students office submitted a Request for Assistance with needs related to food and housing insecurity and lack of basic funds for students. To address this request, a doctoral Capstone team conducted a problem and context analysis, literature review, student focus groups, and an internal survey of departments. The goal was to explore the undergraduate experience of unmet needs and to identify gaps and overlaps in basic needs support and services already provided at VCU. Findings suggest that students do not know the resources available to them through the Dean of Students office, that students …

Driven By Personality: Exploring The Relationship Between Custom Cars And Self-Expression, Tharwa Dalansi

Theses and Dissertations

Custom Car Culture (CCC) is a form of creativity that emerges from personal identities and passions. It involves the restoration, modification and personal adornment of commercially manufactured cars. This process creates a journey, where the enthusiast goes through multiple phases of self-reflection. But due to a lack of local resources, Qatar-based CCC enthusiasts often have to send their cars abroad to Dubai or Japan in order to customize them, relinquishing creative control in the process.

In response to these challenges, based on observations and interviews conducted among actual CCC enthusiasts, I develop a platform for engagement between these enthusiasts and …