Open Access. Powered by Scholars. Published by Universities.®
- Discipline
-
- Social and Behavioral Sciences (1843)
- Medicine and Health Sciences (1051)
- Psychology (939)
- Arts and Humanities (789)
- Education (772)
-
- Sociology (516)
- Race and Ethnicity (389)
- Art and Design (277)
- Art Education (213)
- Clinical Psychology (196)
- Higher Education (171)
- Psychiatry and Psychology (168)
- Fine Arts (153)
- Dentistry (145)
- Health Psychology (145)
- Social Work (139)
- Public Affairs, Public Policy and Public Administration (135)
- Physical Sciences and Mathematics (131)
- Teacher Education and Professional Development (119)
- Counseling Psychology (113)
- Life Sciences (113)
- Public Health (111)
- Nursing (110)
- History (99)
- Educational Leadership (97)
- Interdisciplinary Arts and Media (89)
- Medical Specialties (89)
- Mental and Social Health (89)
- Art Practice (84)
- Feminist, Gender, and Sexuality Studies (84)
- Keyword
-
- Virginia Commonwealth University (248)
- Catalog (169)
- Bulletin (168)
- Book review (95)
- Psychology (88)
-
- Commencement Program (78)
- Depression (74)
- Dentistry (71)
- Mental health (65)
- Anxiety (58)
- Education (56)
- Stress (45)
- Art (42)
- Gender (41)
- Race (41)
- Women (40)
- Obesity (39)
- College students (38)
- Culture (37)
- Identity (36)
- Mindfulness (35)
- African American (34)
- Theatre (34)
- Trauma (34)
- Adolescence (33)
- Alcohol (32)
- Art Education (32)
- Adolescents (31)
- Substance use (31)
- Full Issue (30)
- Publication Year
- Publication
-
- Theses and Dissertations (2459)
- Commonwealth Times, 1969- (884)
- Proscript, 1940-1969 (377)
- UROP Posters (191)
- VCU Bulletins (185)
-
- Journal of Social Theory in Art Education (168)
- VCU Today, 1972-1988 (153)
- Explorations in Ethnic Studies (144)
- VCU Voice, 1988-1998 (139)
- MCV/Q, Medical College of Virginia Quarterly (119)
- Explorations in Sights and Sounds (112)
- Ethnic Studies Review (97)
- VCU Commencement Programs (78)
- The Medicovan, 1948-1973 (74)
- Journal of Mathematics and Science: Collaborative Explorations (73)
- Journal of Prison Education and Reentry (2014-2023) (67)
- Psychiatry Publications (62)
- VCU Magazine, 1971-1993 (60)
- Graduate Research Posters (58)
- Psychology Publications (55)
- Menorah Review (50)
- Virginia Dental Journal (50)
- Richmond Music Journal (43)
- The Atlas, 1929-1939 (42)
- The Scarab, 1952-2010 (42)
- IRBEH/Spit for Science Publications and Presentations (39)
- Journal of Hip Hop Studies (37)
- AUCTUS: The Journal of Undergraduate Research and Creative Scholarship (36)
- Reflections in Ink, 1978-1994 (36)
- VCU Board of Visitors Minutes (36)
- Publication Type
- File Type
Articles 4051 - 4080 of 6812
Full-Text Articles in Entire DC Network
The Photographer's Wife: Emmet Gowin's Photographs Of Edith, Mikell Waters Brown
The Photographer's Wife: Emmet Gowin's Photographs Of Edith, Mikell Waters Brown
Theses and Dissertations
Exemplified in the oeuvres of photographers Alfred Stieglitz, Harry Callahan, Lee Friedlander, and Emmet Gowin, the photographer's wife is a distinctive subject in twentieth-century American fine-art photography that fuses the domains of public and private life through the conflation of art and marriage. The transgressive nature of this juncture can be located in a confluence of gazes - the artist's, the subject's, and the viewer's - that are embroiled in constructing subjectivities. The phrase "photographer's wife" underscores an assumed imbalance of power reflecting a binary of active/passive, artist/model, and husband/wife. It is this study's contention that the complexity of the …
The Civil War: A Collaboration In Direction And Choreography, Cara E. Rawlings
The Civil War: A Collaboration In Direction And Choreography, Cara E. Rawlings
Theses and Dissertations
This text is a partial record of the development of the Virginia Commonwealth University production of The Civil War: A Musical that opened on April 7, 2005 for a three-week run ending April 28, 2005. The greater part of the text is devoted to the evaluation of the underlying principles of direction and choreography applied in the creation of an artistically aid financially successful production of this size. Included in the evaluation of The Civil War: A Musical are analyses of the directors' --Patti D'Beck and David Leong --individual creative processes, aesthetics, and working styles. The result of this evaluation …
Delivery Of Smoke Toxicants From Cigarettes Made In Developed And Developing Countries: A Comparison Of U.S. Full Flavor And Ultra Light Brands With Syrian Cigarettes, Lynn M. Anderson
Theses and Dissertations
Clinical research is needed to understand how cigarette toxicant yield affects smoker toxicant exposure. While there is much clinical research on yield and exposure in developed countries, there is little in developing countries. Forty smokers completed one, 4-hour session to compare yield and exposure of different cigarettes. Participants smoked three cigarettes under controlled topography conditions: one U.S. 111 flavor, one U.S. ultra light, and one Syrian cigarette, with 90 minutes between cigarettes. Sessions differed by Syrian brand; 21 participants smoked Alhamraa while 19 smoked A1 Sham cigarettes. Blood nicotine and breath CO samples were obtained, HR was monitored and subjective …
The Experience Of Decision Making In Adolescent Females And Young Women With Mobility Limiting Disorders, Bernice Balzer Allen
The Experience Of Decision Making In Adolescent Females And Young Women With Mobility Limiting Disorders, Bernice Balzer Allen
Theses and Dissertations
Young women with mobility limiting disorders face many challenges as they move through adolescence into young adulthood. In addition to the challenges of this developmental period, they must consider their disability as they manage their lives. Competent decision making is a foundational skill for self-management and for transition in adulthood. It is also a protective factor for resilience.There is little research on decision making in adolescents with disabilities. Therefore, the purpose of this qualitative study was to explore the decision making experiences of female adolescents and young women with mobility limiting disorders. Theoretical underpinnings for the study included Resilience Theory …
Experimental Navigation And The Creative Process, Teresa A. Engle
Experimental Navigation And The Creative Process, Teresa A. Engle
Theses and Dissertations
For this creative project, I am exploring alternate methods of navigating urban environments, and ways in which this activity can inspire creativity. This process is intended to create a new awareness of the urban landscape, break out of the prescribed, and to inspire innovation. The range of possibilities for this way of navigating is vast, and part of the challenge of my experience has been defining boundaries, assigning variables, and using strategies for exploration making my process inherently morphological. I hope that my work here will encourage others to step out of their comfort zone and experience their environment …
Innovative Interventions For Disordered Eating: A Pilot Comparison Between Dissonance-Based And Yoga Interventions, Karen S. Mitchell
Innovative Interventions For Disordered Eating: A Pilot Comparison Between Dissonance-Based And Yoga Interventions, Karen S. Mitchell
Theses and Dissertations
Disordered eating, including bingeing, dieting, purging, and clinical and subclinical forms of anorexia nervosa, bulimia nervosa, and binge eating disorder, is prevalent among college-aged women. To date, few interventions have successfully reduced risk factors related to disordered eating. One promising intervention utilizes principles of cognitive dissonance to reduce thin-ideal internalization among women at risk for eating disorders. Additionally, the benefits of yoga, including increased awareness of bodily processes, offer hope that this practice might reduce disordered eating symptomatology. The current study compared cognitive dissonance and yoga interventions for disordered eating attitudes and behaviors. Hierarchical regression analyses revealed that there were …
Certified Registered Nurse Anesthetist Performance And Perceptions: Use Of A Handheld, Computerized, Decision Making Aid During Critical Events In A High-Fidelity Human Simulation Environment, Vicki C. Coopmans
Theses and Dissertations
With the increasing focus on patient safety and human error, understanding how practitioners make decisions during critical incidents is important. Despite the move towards evidence-based practice, research shows that much decision making is based on intuition and heuristics (“rules of thumb”). The purpose of this study was to examine and evaluate the methodologic feasibility of a strategy for comparing traditional cognition versus the use of algorithms programmed on a personal digital assistant (FDA) in the management of unanticipated critical events by certified registered nurse anesthetists (CRNAs).
A combined qualitative-quantitative methodology was utilized. The quantitative element consists of a pilot study …
Assessing The Effects Of Momentary Priming On Memory Retention During An Interference Task, Paul Cameron Schutte
Assessing The Effects Of Momentary Priming On Memory Retention During An Interference Task, Paul Cameron Schutte
Theses and Dissertations
A memory aid, that used brief (33ms) presentations of previously learned information (target words), was assessed on its ability to reinforce memory for target words while the subject was performing an interference task. The interference task required subjects to learn new words and thus interfered with their memory of the target words. The brief presentation (momentary memory priming) was hypothesized to refresh the subjects' memory of the target words. 143 subjects, in a within subject design, were given a 33ms presentation of the target memory words during the interference task in a treatment condition and a blank 33ms presentation in …
Influences On Career Self-Efficacy: Examining Attachment, Anya Elizabeth Moon
Influences On Career Self-Efficacy: Examining Attachment, Anya Elizabeth Moon
Theses and Dissertations
This study examined the influences of attachment style and level of optimism on career self-efficacy. It was hypothesized that level of optimism moderates the relationship between attachment style and career self-efficacy. Participants were 173 college students who completed the Experiences in Close Relationships (ECR; K.A. Brennan, C.L. Clark, & P.R. Shaver, 1998), the Life Orientation Test - Revised (LOT-R; M. Sheier, C. Carver, & M. Bridges, 1994), and the Career Decision-Making Self-Efficacy - Short Form (CDMSE-SF; N. Betz, K. Klein, & K. Taylor, 1996). The moderator model was not supported, but hierarchical regression revealed a positive relationship between optimism and …
Defending Defense: Circular Arguments About Artmaking, Ryan Mulligan
Defending Defense: Circular Arguments About Artmaking, Ryan Mulligan
Theses and Dissertations
This paper is a critical look at video and performance arts intrinsic relationship to culture. Investigations of storytelling, personal mythology, fear, and image saturation. Think-pieces on the nature of art in an entertainment society. Juggling a brief overview of various works and their relation to over arching themes of game theory, dark humor, and fascination with media. An in depth look at the process of the thesis show, "Defense is the Best Defense." Multiple takes on the thesis exhibit counterbalance the need for contemporary art to include description. This paper is a detailed look at the process of Ryan Mulligan's …
Asperger's Syndrome And Non-Verbal Learning Disabilities: A Study Of Differential Diagnosis Agreement Across Disciplines, Norman J. Geller
Asperger's Syndrome And Non-Verbal Learning Disabilities: A Study Of Differential Diagnosis Agreement Across Disciplines, Norman J. Geller
Theses and Dissertations
Mental health professionals tend to have a clinical perspective that is dependent upon Diagnostic and Statistical Manual of Mental Disorders-IV-TR (DSM-IV) criteria for a differential diagnosis. School-based clinicians are bound by regulations governing special education placement established by Individuals with Disabilities Education Act (IDEA). While both sets of clinicians generate diagnostic recommendations for students, the guidelines and criteria are not of parallel descriptors. AS is only a diagnosis provided for in DSM-IV. Non-verbal learning disability (NVLD) and high functioning autism (HFA) are addressed in both DSM-IV and IDEA. The dilemma presented to clinicians is intertwining the terminology of both fields …
Assessing The Relationship Between Socioeconomic Variables And Risk Of Overweight Among Children 6 Years Of Age, Marilyn Cochon Batan
Assessing The Relationship Between Socioeconomic Variables And Risk Of Overweight Among Children 6 Years Of Age, Marilyn Cochon Batan
Theses and Dissertations
Background: The percentage of overweight children has tripled in the last thirty years. Inconsistent findings are published regarding the relationship between socioeconomic variables and being overweight in childhood.Objective: To determine whether socioeconomic variables are associated with risk of being overweight among six year olds. Methods: Six year olds with BMI data were selected from the National Survey of Children's Health (n=4,362). Variables were coded and a low socioeconomic index was created. Using population weights, descriptive statistics were generated and regression was utilized to assess the relationship between socioeconomic variables and being 'at risk' for overweight. Socioeconomic variables were also compared …
Building Hypertext In The Elementary School Art Classroom: An Integrated Approach To Learning And Curriculum, Talitha Church
Building Hypertext In The Elementary School Art Classroom: An Integrated Approach To Learning And Curriculum, Talitha Church
Theses and Dissertations
In response to the many demands and pressures faced by both students and teachers in public schools, the art teacher in this action research study searched for ways to change her teaching practices to facilitate active inquiry. She utilized Thinking Maps®, a specialized form of graphic organizers, and Inspiration®, a hypertext linking program to promote interdisciplinary teaching and learning. The goals of the study were to increase student engagement, improve learning, and promote higher order thinking in elementary school art classes. The target group was comprised of the third grade students at Saunders Elementary School in Newport News, Virginia. Each …
Co-Parenting In Intact And Divorced Families: Its Impact On Young Adult Adjustment, Jill A. Ferrante
Co-Parenting In Intact And Divorced Families: Its Impact On Young Adult Adjustment, Jill A. Ferrante
Theses and Dissertations
Co-parenting is the ideal parenting relationship after divorce, characterized by involvement of both parents in all decisions regarding their children. Children who report that their parents demonstrate healthy co-parenting are generally better adjusted than their peers who experience unhealthy co-parenting. The present study examined the potential mediating roles of co-parenting and parenting practices upon the relationship between marital status and young adult adjustment. Data were analyzed via structural equation modeling. Participants were 340 undergraduate students from intact and divorced/separated families. Data were obtained via questionnaires that tapped a range of adjustment factors (i.e., mental health, fear of intimacy, work ethic, …
Paragon/Paragone: Raphael's Portrait Of Baldassare Castiglione (1514-16) In The Context Of Il Cortegiano, Margaret Ann Southwick
Paragon/Paragone: Raphael's Portrait Of Baldassare Castiglione (1514-16) In The Context Of Il Cortegiano, Margaret Ann Southwick
Theses and Dissertations
This thesis argues that Raphael's portrait, Baldassare Castiglione, is three portraits in one: 1) a "speaking likeness" of the subject, 2) a portrait of the "perfect" courtier, and 3) a "shadow" portrait of the Court of Urbino in the early sixteenth century. The formal analysis of the painting is presented in the context of the paragone of word and image expounded by its subject in his masterpiece, Il Cortegiano. Both author and artist demonstrate the concepts of sprezzatura (an artful artlessness) and grazia (graceful elegance) in the creation of their portraits, as well as avoidance of affetazione (affectation). It is …
Child's Temperament And Conscious Sedation Outcomes, Jennifer Mark Dixon
Child's Temperament And Conscious Sedation Outcomes, Jennifer Mark Dixon
Theses and Dissertations
The purpose of this study was to investigate the role of child temperament and its effect on the outcome of conscious sedation using the following agents: Chloral Hydrate (35mg/kg), Meperidine (2mg/kg), and Hydroxyzine (2mg/kg).The Emotionality, Activity, Sociability (EAS) Temperament Survey for Children was used to measure the child's temperament. The temperament survey measures three realms (Emotionality, Activity, Sociability/Shyness). The sedation outcomes were rated using the modified North Carolina Behavior Rating Scale (NCBRS) from 1-4 (Quiet, Annoyed, Upset, and Wild). The final sample population consisted of 34 children, 24 girls (71%) and 10 boys (29%), ranging in age from 0-9 years …
Psychosocial Adjustment Of Adolescent Cancer Survivors: Time Perspective And Positive Emotions As Mediators To Quality Of Life And Benefit Finding, Matthew John Bitsko
Psychosocial Adjustment Of Adolescent Cancer Survivors: Time Perspective And Positive Emotions As Mediators To Quality Of Life And Benefit Finding, Matthew John Bitsko
Theses and Dissertations
Adolescents with cancer are surviving at improved rates with levels of psychopathology in line with their healthy peers. Thus, recent psycho-oncology research is focusing on finding significant predictors to their positive adjustment and psychosocial functioning. The author examined adolescent cancer survivors (n = 50; diagnosis age = 10 21; 2 10 years post-diagnosis) to test the mediation effects of positive emotionns (satisfaction with life, subjective happiness, and optimism) and time perspective on the outcome variables quality of life and benefit finding with demographic/medical variables (gender, number of treatments received for cancer, and previous psychotherapy) as independent variables. Results …
Help-Seeking For Depression In Rural Women: A Community Portrait, Vicky Mitchell Fisher
Help-Seeking For Depression In Rural Women: A Community Portrait, Vicky Mitchell Fisher
Theses and Dissertations
This study was conducted with fourteen participants who lived in a rural Virginia community. The focus of the study was exploration of the nature of the experience of depression and of help-seeking for depression in one rural woman and in her community social network. The need for exploration of the community social network was influenced by the DeFacto Services Model of Rural Mental Health, which emphasized the influence of community factors in making decisions to seek mental health care. Findings of the study included the following themes, which related to the nature of depression: 1) linkage of experiential depression to …
Addiction And Recovery Experiences Of African American Women: A Phenomenological Study, Patricia Diana Hill
Addiction And Recovery Experiences Of African American Women: A Phenomenological Study, Patricia Diana Hill
Theses and Dissertations
Historically, substance abuse research has for the most part excluded African American women. The small body of existing substance abuse research regarding African American women does not examine gender and socio-cultural issues from African American women's perspectives. The purpose of this phenomenological study is to develop a deeper, contextual understanding of the experiences and perspectives of this marginalized population of women. The major goal of the study is to examine the perspectives of African American women about their substance abuse, treatment and recovery. The knowledge gained from this research with African American women regarding their experiences and specific needs in …
Complementary And Alternative Medicine And Diet Change In Southern Rural Residents Enrolled In A Cancer Prevention Intervention Trial, Amanda Kracen
Complementary And Alternative Medicine And Diet Change In Southern Rural Residents Enrolled In A Cancer Prevention Intervention Trial, Amanda Kracen
Theses and Dissertations
Using data from The Rural Physician Cancer Prevention Project, a dietary intervention trial, this cross-sectional, longitudinal study explored predictors of complementary and alternative medicine (CAM) use in a Southern, rural population (N = 375). Participants' dietary knowledge, stage of change, and dietary behavior were examined at baseline and 1 and 12 months after the intervention. More than half the participants (mean age = 48 years; 60% female; 60% Caucasian) reported using CAM. Logistic regression indicated that age, education, ethnicity and trust in physician affect the likelihood of CAM use. Hierarchical multiple regressions suggested that CAM use was associated with healthier …
Relation Of Healthcare Provider-Patient Interpersonal Impacts And Health Related Control Appraisals To Patients' Satisfaction And Compliance With Treatment, Thomas A. Campbell
Relation Of Healthcare Provider-Patient Interpersonal Impacts And Health Related Control Appraisals To Patients' Satisfaction And Compliance With Treatment, Thomas A. Campbell
Theses and Dissertations
The current study examined healthcare provider-patient interpersonal impacts and health related control appraisals to patients' satisfaction and compliance with treatment recommendations. Secondary outcomes such as patient satisfaction are becoming increasingly important, and compliance with treatment can have direct effects on primary outcomes. Eighty-one patients at a large, urban university student health center participated in the current study. Participants completed participatory style and interpersonal impact measures both before and after the visit with their provider, and completed satisfaction questionnaires immediately following the visit, and at the two-week follow-up along with a measure assessing compliance with treatment recommendations. Providers also completed interpersonal …
Magic Mountain, Diana Al-Hadid
Magic Mountain, Diana Al-Hadid
Theses and Dissertations
My installations are propositions for an imaginary world that relies on its own internal logic, a world of believability without recognition. While the work references landscape it also emphasizes its contrivance, as it is automatically estranged in an "unnatural" gallery setting. I subvert or de-familiarize the materials and processes that I use in the service of creating a fictitious environment. My places are impossible places. They are irregular, illogical, and unstable. Our imagination can be one of most dangerous things to psychological stability as it is an inventory of all things possible, no matter how irrational or improbable. The irrational …
Searching For The Transatlantic Freedom: The Art Of Valerie Maynard, Karen Berisford Getty
Searching For The Transatlantic Freedom: The Art Of Valerie Maynard, Karen Berisford Getty
Theses and Dissertations
This thesis focuses on an African-American female artist, Valerie Maynard, examining how she synthesizes African and American elements in her works. It provides detailed formal and iconographical analyses, revealing concealed meanings and paying special attention to those works with which the artist mirrors the Black experience in the United States and Africa on the other side of the Atlantic. In the process, the thesis sheds new light on the significance of Valerie Maynard's work and how she has used some of them to embody the Black quest for freedom and social justice during the Civil Rights struggle of the 1960s …
Epileptogenesis Causes Long-Term Plasticity Changes In Calbindin D-28k In The Rat Pilocarpine Model Of Acquired Epilepsy, Anne Johnston Harrison
Epileptogenesis Causes Long-Term Plasticity Changes In Calbindin D-28k In The Rat Pilocarpine Model Of Acquired Epilepsy, Anne Johnston Harrison
Theses and Dissertations
Epilepsy is one of the most common neurological disorders, affecting more than 2% of children and 1% of adults in the U.S. Emerging research has demonstrated that calcium, as a major second messenger system, underlies many of these injury-induced plasticity changes associated with the development of epilepsy. Recent evidence has suggested that long term elevations in neuronal resting calcium levels play a role in initiating and maintaining epileptogenesis (the development of epilepsy). Collaborations between our lab and others have produced microarray data that suggests that a major calcium-binding protein, calbindin D-28k, mRNA levels are decreased in epileptic rats even up …
Age At Sexual Assault And Posttraumatic Stress Disorder In Females Residents Of Virginia, Ahmed Gasmelseed Babiker
Age At Sexual Assault And Posttraumatic Stress Disorder In Females Residents Of Virginia, Ahmed Gasmelseed Babiker
Theses and Dissertations
Background Post Traumatic Stress Disorder (PTSD) is a psychiatric debilitating condition that can occur in individuals who experience extremely stressful or traumatic life events. Sexual assault is considered as one of the most traumatic stressor in life. Although few studies investigated the association between history of sexual assault and PTSD, no studies have examined the impact of age at sexual assault on PTSD.Method A cross-sectional telephone survey was conducted among adult female residents of Virginia from November 2002 to February 2003. A total of 1,769 women aged 18 and older were interviewed using a random digit dialing method. Detailed screening …
The Influence Of Lipid Composition On The Binding Of Ldl To Chondroitin 6-Sulphate, Wilma Espiritu
The Influence Of Lipid Composition On The Binding Of Ldl To Chondroitin 6-Sulphate, Wilma Espiritu
Theses and Dissertations
The interaction between low-density lipoprotein (LDL) and glycosaminoglycans is a key factor in atherosclerosis. The present study examines the characteristics of LDL and its binding properties with the main glycosaminoglycan of the vascular wall, chondroitin 6- sulphate (C6S). The compositional characteristics that were studied for each LDL sample were phase transition temperature, phospholipid content, free cholesterol content, cholesteryl ester content, triglyceride content, and size. Correlations of these characteristics with LDL-C6S binding were analyzed using a turbidity assay. Our results showed that there is no correlation between LDL-C6S binding and phase transition temperature, triglyceride content, or size. Strong correlations were present …
Flight Signs, Flight Symbols, Margaret Mary Urban
Flight Signs, Flight Symbols, Margaret Mary Urban
Theses and Dissertations
I am investigating the significance of historic events of flight through image making; particularly incidents that captured the collective imagination and became part of our cultural memory. These events have surpassed mere entries in historical texts and become mythic. In the terms of Jungian psychology, they have become symbolic. In terms of Semiotics, they have become signs. Through photographs and installation, I seek to understand their presence in my, and our, unconscious mind.
Educational Survey On Eating Disorders In Post-Graduate Pediatric Curriculum, Priya Jitendraprasad Patel
Educational Survey On Eating Disorders In Post-Graduate Pediatric Curriculum, Priya Jitendraprasad Patel
Theses and Dissertations
Purpose: The purpose of this study was to assess if the topic of eating disorders is a part of post-graduate pediatric dental residency training curriculum. This study examined if there is a need for increased training of pediatric dental residents regarding the oral manifestations and treatment of patients with eating disorders.Methods: A cross-sectional online survey was used to compare data from all 66 post-graduate pediatric dental residency program directors. After thirty days a second emailing was conducted, with an additional thirty days to reply. Univariate distributions were obtained and percents for all items were based on the total number of …
Global Discontents, Priyadarshini A. Khatri
Global Discontents, Priyadarshini A. Khatri
Theses and Dissertations
My creative project explores toys as means to express economic issues of globalization. By exploiting the educational and imaginative aspects of toys for adults and children, I intend to reflect on the impact and pressures of globalization on employment, technology and environment. In creating these toys I hope to make a visual statement concerning critical issues of human survival, sustainability and the divisive side of globalization.
Dual Mechanism Analgesia-Enhancing Agents, Shawquia Elithia Young
Dual Mechanism Analgesia-Enhancing Agents, Shawquia Elithia Young
Theses and Dissertations
Currently, there is an increasing need for novel analgesics that are potent but lack undesired side effects. Recent studies have shown that both 5-HT3 receptors and α2B- adrenoceptors play a role in antinociception. MD-354, N-(3-chlorophenyl)guanidine, has a high-affinity both for 5-HT3 and α2B- adrenoceptors and could be viewed as the first example of a rather selective 5-HT3/α2B- adrenoceptor ligand. MD-354, inactive by itself, potentiates the antinociceptive effects of an inactive dose of clonidine in the mouse tail- flick assay. An attempt to determine the underlying mechanism of this potentiating effect was the purpose of the present investigation. The studies focused …