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Development And Psychometric Validation Of A Novel Patient Survey To Assess Perceived Quality Of Substance Abuse Treatment In South Africa, Bronwyn Myers, Rajen Govender, J. Randy Koch, Ron Manderscheid, Kim Johnson, Charles D. H. Parry

Psychology Publications

Background

A hybrid performance measurement system that combines patient-reported outcome data with administrative data has been developed for South African substance abuse treatment services. This paper describes the development and psychometric validation of one component of this system, the South African Addiction Treatment Services Assessment (SAATSA).

Methods

First, a national steering committee identified five domains and corresponding indicators on which treatment quality should be assessed. A decision was made to develop a patient survey to assess several of these indicators. A stakeholder work group sourced survey items and generated additional items where appropriate. The feasibility and face validity of these …

Electronic Nicotine Delivery Devices, And Their Impact On Health And Patterns Of Tobacco Use: A Systematic Review Protocol, Allison M. Glasser, Caroline O. Cobb, Lyubov Teplitskaya, Ollie Ganz, Lauren Katz, Shyanika W. Rose, Shari Feirman, Andrea C. Villanti

Psychology Publications

Introduction

E-cigarettes or electronic nicotine delivery systems (ENDS) have recently attracted considerable attention. Among some individuals there is strong debate and a polarisation of views about the public health benefits versus harms of ENDS. With little regulation, the ENDS market is evolving, and new products are introduced and marketed constantly. Rapid developments in manufacturing, marketing and consumer domains related to ENDS will warrant frequent re-evaluation, based on the state of the evolving science. The purpose of this article is to describe a protocol for an ongoing comprehensive review of the published scientific literature on ENDS.

Methods and analysis

We will …

Electronic Cigarettes And Nicotine Dependence: Evolving Products, Evolving Problems, Caroline O. Cobb, Peter S. Hendricks, Thomas Eissenberg

Psychology Publications

Electronic cigarettes (ECIGs) use an electric heater to aerosolize a liquid that usually contains propylene glycol, vegetable glycerin, flavorants, and the dependence-producing drug nicotine. ECIG-induced nicotine dependence has become an important concern, as some ECIGs deliver very little nicotine while some may exceed the nicotine delivery profile of a tobacco cigarette. This variability is relevant to tobacco cigarette smokers who try to switch to ECIGs. Products with very low nicotine delivery may not substitute for tobacco cigarettes, so that ECIG use is accompanied by little reduced risk of cigarette-caused disease. Products with very high nicotine delivery may make quitting ECIGs …

One-Year Trajectories Of Mental And Physical Functioning During And After Rehabilitation Among Individuals With Disabilities, Line Preede, Martin Saebu, Paul B. Perrin, Astrid Nyquist, Haakon Dalen, Erik Bautz-Holter, Cecilie Røe

Psychology Publications

Purpose

First, to evaluate the trajectories of physical and mental functioning in individuals with chronic disabilities receiving adapted physical activity-based rehabilitation. Second, to determine whether demographic factors, disability group, pain, fatigue and self-efficacy at baseline influenced these trajectories.

Research design

A prospective intervention study.

Methods

The study included 214 subjects with chronic disabilities who were admitted to a four-week adapted physical activity-based rehabilitation stay at Beitostølen Healthsports Centre. The subjects completed written questionnaires eight and four weeks before the rehabilitation, at admission to and discharge from the rehabilitation centre and again four weeks and 12 months after discharge. Multilevel models …

Personal Strengths And Health Related Quality Of Life In Dementia Caregivers From Latin America, Stephen Trapp, Paul B. Perrin, Richa Aggarwal, Silvina Victoria Peralta, Miriam E. Stolfi, Eliana Morelli, Leticia Aracely Peña Obeso, Juan Carlos Arango-Lasprilla

Psychology Publications

The research literature has begun to demonstrate associations between personal strengths and enhanced psychosocial functioning of dementia caregivers, but these relationships have not been examined in the context of dementia caregivers in Latin America. The present study examined whether personal strengths, including resilience, optimism, and sense of coherence, were associated with mental and physical health related quality of life (HRQOL) in 130 dementia caregivers in Mexico and Argentina. Structural equation modeling found that the personal strengths collectively accounted for 58.4% of the variance in caregiver mental HRQOL, and resilience, sense of coherence, and optimism each had unique effects. In comparison, …

Disparities In The Completion Of Steps To Kidney Transplantation: Protocol For A Systematic Review, Heather M. Traino, Camillo W. Nonterah, John W. Cyrus, Avrum Gillespie, Megan Urbanski, Michael Adair-Kriz

Psychology Publications

Introduction

Disparities in access to transplantation have been well documented. The extant literature, however, focuses largely on disparities and related barriers for African-American patients and none has used the steps to transplantation as a guiding framework. This review will catalogue disparities in the steps to transplantation as well as the barriers and facilitators to completion of each step identified in the extant literature. The results of the review will be used to generate recommendations for future research to improve equity in access to kidney transplantation.

Methods and analysis

Standard procedures will be used in the conduct of the review. Searches …

Integrating Mrna And Mirna Weighted Gene Co-Expression Networks With Eqtls In The Nucleus Accumbens Of Subjects With Alcohol Dependence, Mohammed Mamdani, Vernell Williamson, Gowon O. Mcmichael, Tana Blevins, Fazil Aliev, Amy Adkins, Laura Hack, Tim Bigdeli, Andrew D. Van Der Vaart, Bradley Todd Webb, Silviu-Alin Bacanu, Gursharan Kalsi, Coga Consortium, Kenneth S. Kendler, Michael F. Miles, Danielle Dick, Brien P. Riley, Catherine Dumur, Vladimir I. Vladimirov

Psychology Publications

Alcohol consumption is known to lead to gene expression changes in the brain. After performing weighted gene co-expression network analyses (WGCNA) on genome-wide mRNA and microRNA (miRNA) expression in Nucleus Accumbens (NAc) of subjects with alcohol dependence (AD; N = 18) and of matched controls (N = 18), six mRNA and three miRNA modules significantly correlated with AD were identified (Bonferoni-adj. p≤ 0.05). Cell-type-specific transcriptome analyses revealed two of the mRNA modules to be enriched for neuronal specific marker genes and downregulated in AD, whereas the remaining four mRNA modules were enriched for astrocyte and microglial specific marker genes and …

A Disproportionate Burden Of Care: Gender Differences In Mental Health, Health-Related Quality Of Life, And Social Support In Mexican Multiple Sclerosis Caregivers, Paul B. Perrin, Ivan Panyavin, Alejandra Morlett Paredes, Adriana Aguayo, Miguel Angel Macias, Brenda Rabago, Sandra J. Fulton Picot, Juan Carlos Arango-Lasprilla

Psychology Publications

Background. Multiple sclerosis (MS) rates in Latin America are increasing, and caregivers there experience reduced mental and physical health. Based on rigid gender roles in Latin America, women more often assume caregiving duties, yet the differential impact on women of these duties is unknown. Methods. This study examined gender differences in mental health (Patient Health Questionnaire-9, Satisfaction with Life Scale, Rosenberg Self-Esteem Scale, State-Trait Anxiety Inventory, and Zarit Burden Inventory), health-related quality of life (HRQOL; Short Form-36), and social support (Interpersonal Support Evaluation List-12) in 81 (66.7% women) Mexican MS caregivers. Results. As compared to men caregivers, women had lower …

Electronic Cigarettes And Nicotine Dependence: Evolving Products, Evolving Problems, Caroline O. Cobb, Peter S. Hendricks, Thomas Eissenberg

Psychology Publications

Electronic cigarettes (ECIGs) use an electric heater to aerosolize a liquid that usually contains propylene glycol, vegetable glycerin, flavorants, and the dependence-producing drug nicotine. ECIG-induced nicotine dependence has become an important concern, as some ECIGs deliver very little nicotine while some may exceed the nicotine delivery profile of a tobacco cigarette. This variability is relevant to tobacco cigarette smokers who try to switch to ECIGs. Products with very low nicotine delivery may not substitute for tobacco cigarettes, so that ECIG use is accompanied by little reduced risk of cigarette-caused disease. Products with very high nicotine delivery may make quitting ECIGs …

Patterns Of Substance Use Across The First Year Of College And Associated Risk Factors, Seung Bin Cho, Danielle C. Llaneza, Amy E. Adkins, Megan Cooke, Kenneth S. Kendler, Shaunna L. Clark, Danielle M. Dick

Psychology Publications

Starting college is a major life transition. This study aims to characterize patterns of substance use across a variety of substances across the first year of college and identify associated factors. We used data from the first cohort (N = 2056, 1240 females) of the “Spit for Science” sample, a study of incoming freshmen at a large urban university. Latent transition analysis was applied to alcohol, tobacco, cannabis, and other illicit drug uses measured at the beginning of the fall semester and midway through the spring semester. Covariates across multiple domains – including personality, drinking motivations and expectancy, high …

Developmental Changes In Genetic And Shared Environmental Contributions To Smoking Initiation And Subsequent Smoking Quantity In Adolescence And Young Adulthood, Cristina B. Bares, Kenneth S. Kendler, Hermine H. Maes

Psychiatry Publications

Background

Few studies examining the genetic architecture of cigarette smoking have focused on adolescents or examined developmental changes in additive genetic, shared environment and unique environmental influences on liability to initiate cigarette smoking and quantity of cigarettes smoked. The aim of this study is to add to the literature on liability to initiate and use cigarettes during adolescence using a nationally representative sample.

Method

Data for this study came from adolescent and young adult twin pairs (ages 14-33) from the National Longitudinal Study of Adolescent to Adult Health. We ran a series of developmental causal-contingent-common pathway models to examine whether …

Genetic Network Properties Of The Human Cortex Based On Regional Thickness And Surface Area Measures, Anna R. Docherty, Chelsea K. Sawyers, Matthew S. Panizzon, Michael C. Neale, Lisa T. Eyler, Christine Fennema-Notestine, Carol E. Franz, Chi-Hua Chen, Linda K. Mcevoy, Brad Verhulst, Ming T. Tsuang, William S. Kremen

Psychiatry Publications

We examined network properties of genetic covariance between average cortical thickness (CT) and surface area (SA) within genetically-identified cortical parcellations that we previously derived from human cortical genetic maps using vertex-wise fuzzy clustering analysis with high spatial resolution. There were 24 hierarchical parcellations based on vertex-wise CT and 24 based on vertex-wise SA expansion/contraction; in both cases the 12 parcellations per hemisphere were largely symmetrical. We utilized three techniques—biometrical genetic modeling, cluster analysis, and graph theory—to examine genetic relationships and network properties within and between the 48 parcellation measures. Biometrical modeling indicated significant shared genetic covariance between size of several …

Political Attitudes Develop Independently Of Personality Traits, Peter K. Hatemi, Brad Verhulst

Psychiatry Publications

The primary assumption within the recent personality and political orientations literature is that personality traits cause people to develop political attitudes. In contrast, research relying on traditional psychological and developmental theories suggests the relationship between most personality dimensions and political orientations are either not significant or weak. Research from behavioral genetics suggests the covariance between personality and political preferences is not causal, but due to a common, latent genetic factor that mutually influences both. The contradictory assumptions and findings from these research streams have yet to be resolved. This is in part due to the reliance on cross-sectional data and …

Genome-Wide Association Data Suggest Abcb1 And Immune-Related Gene Sets May Be Involved In Adult Antisocial Behavior, J E. Salvatore, A C. Edwards, J N. Mcclintick, T B. Bidgeli, A Adkins, F Aliev, H J. Edenberg, T Foround, V Hesselbrock, J Kramer, J I. Nurnberger, M Schuckit, J A. Tischfield, X Xuei, D Dick

Psychiatry Publications

Adult antisocial behavior (AAB) is moderately heritable, relatively common and has adverse consequences for individuals and society. We examined the molecular genetic basis of AAB in 1379 participants from a case–control study in which the cases met criteria for alcohol dependence. We also examined whether genes of interest were expressed in human brain. AAB was measured using a count of the number of Antisocial Personality Disorder criteria endorsed under criterion A from the Diagnostic and Statistical Manual of Mental Disorders, 4th Edition (DSM-IV). Participants were genotyped on the Illumina Human 1M BeadChip. In total, all single-nucleotide polymorphisms (SNPs) accounted for …

Who Are Those “Risk-Taking Adolescents”? Individual Differences In Developmental Neuroimaging Research, James M. Bjork, Dustin A. Pardini

Psychiatry Publications

Functional magnetic resonance imaging (fMRI) has illuminated the development of human brain function. Some of this work in typically-developing youth has ostensibly captured neural underpinnings of adolescent behavior which is characterized by risk-seeking propensity, according to psychometric questionnaires and a wealth of anecdote. Notably, cross-sectional comparisons have revealed age-dependent differences between adolescents and other age groups in regional brain responsiveness to prospective or experienced rewards (usually greater in adolescents) or penalties (usually diminished in adolescents). These differences have been interpreted as reflecting an imbalance between motivational drive and behavioral control mechanisms, especially in mid-adolescence, thus promoting greater risk-taking. While intriguing, …

Giftedness As Property: Troubling Whiteness, Wealth, And Gifted Education In The Us, Katherine Cumings Mansfield

Educational Leadership Publications

The purposes of this article are to illumine the racist genealogy of gifted education policies and practices in the United States, to demonstrate how deficit discourses continue today, and to provide personal examples from the field of how educators can begin to question the status quo, resist taken-for-granted assumptions, and alternatively make substantive changes at the local level. I also aim to demonstrate how giftedness is an example of whiteness as property, or unearned white privilege, that, unintentionally or not, maintains a social caste system in schools

Upward Communication About Cancer Screening—Adolescent Daughter To Mother, Maghboeba Mosavel, Katie A. Ports

Social and Behavioral Sciences Publications

Substantial breast and cervical cancer disparities exist in the United States, particularly among African American women with low social economic status. There is considerable potential for discussions about cancer prevention between mothers and daughters. However, upward communication, from child to parent, remains a relatively novel research area, and it remains unclear how receptive mothers would be to messages from their daughter about cancer, a topic that may be considered culturally inappropriate for daughters to initiate. In this study, we simulated cancer message delivery to daughters and then conducted direct observation of daughters as they recalled and shared the message with …

Understanding Cognition Across Modalities For The Assessment Of Digital Resources, Valeriana Colon

Teaching and Learning Publications

Drawing from the theories of the cognitive process, this paper explores the transmission, retention and transformation of information across oral, written, and digital modes of communication and how these concepts can be used to examine the assessment of digital resource tools. The exploration of interactions across modes of communication is used to gain an understanding of the interaction between the student, digital resource and teacher. Cognitive theory is considered as a basis for the assessment of digital resource tools. Lastly, principles for the assessment of digital resource tools are presented along with how assessment can be incorporated in the educational …

From Local To Global: Making The Leap In Teacher Education, Hillary Parkhouse, Jocelyn Glazier, Ariel Tichnor-Wagner, Jessie Montana Cain

Teaching and Learning Publications

As the world becomes increasingly globalized, teachers must prepare a diverse group of students with new skills and mindsets necessary to engage in this global environment. This requires changes in teacher education, including expansion of instructional lenses from the local to the global. This case study examined how one teacher educator attempted to incorporate global competency into her course on culturally responsive teaching. Using surveys, document analysis, observations, and interviews with both the instructor and her students, the researchers found that some global competencies were developed. Ultimately, however, many areas of global competence were not addressed, due to the course’s …

Identifying Molecular Features Associated With Psychoneurological Symptoms In Women With Breast Cancer Using Multivariate Mixed Models, Qing Zhou, Colleen Jackson-Cook, Debra Lyon, Robert Perera, Kellie Archer

Biostatistics Publications

Breast cancer (BC) is the second most common cancer among women. Research shows many women with BC experience anxiety, depression, and stress (ADS). Epigenetics has recently emerged as a potential mechanism for the development of depression.1 Although there are growing numbers of research studies indicating that epigenetic changes are associated with ADS, there is currently no evidence that this association is present in women with BC. The goal of this study was to identify high-throughput methylation sites (CpG sites) that are associated with three psychoneurological symptoms (ADS) in women with BC. Traditionally, univariate models have been used to examine …

Heterosexism Faced By Adolescents In The Rural United States: A Case For Implementing Student-Made Lgbt Programs, Beau W. Coggsdale

UROP Posters

GSAs, Gay-Straight Alliances, influence the heterosexist environment within a school system, especially rural schools. The data was collected from various journals documenting suicide rates and levels of self-esteem in rural environments. A lot of the data was collected was cross-referenced because of the lack of research into LGBT youth in rural environments. Much of the research that was conducted was focused on ameliorating internalized homophobia of urban LGBT youth instead of rural LGBT youth, so research into LGBT urban youth was applied to those in a rural environment. Heterosexism exists in school systems because of the lack of support for …

The Metabolism Of Alcohol: Risk And Protective Factors, Sydney E. Levan, Amy Adkins, Danielle Dick, Karen G. Chartier

UROP Posters

Purpose: Abstract for poster submission to VCU Poster Symposium for

Undergraduate Research and Creativity

Title: The Metabolism of Alcohol: Risk and Protective Factors

Background: In 2002, it was reported by the National Institutes of Health that

60.3% of college aged students (18-22) drank alcohol in the past month of being

asked, as compared to 51.9% of those not in college. They also found that 20% of

college students met the criteria for at least one alcohol use disorder (AUDs)1.

Many genes have been linked to an increased risk for AUDs and how individuals

with various ethnic backgrounds respond to alcohol. …

The Effects Of Part-Time Work On Sleep Quality In College Students, Katherine A. Beachy, Candace Moore, Magda M. Smith

UROP Posters

Part time work can negatively affect sleeping patterns, resulting in poorer academic performance and a diminished sense of overall well-being. 521 undergraduate students working at least 20 hours per week were surveyed and self-reported post-work experiences and sleep quality. Results of a multiple regression analysis indicated that a block of four post-work experiences (psychological detachment, relaxation, mastery, and control over leisure time) were predictive of self-reported sleep quality. Completion of more mastery experiences and greater control over choosing post-work activities were both statistically significant predictors of higher sleep quality (Sonnentag, Binnewies, & Mojza, 2008).

Can You Please Put Your Phone Away? Examining How The Fomo Phenomenon And Mobile Phone Addiction Affect Human Relationships, Laila A. Chaudhry

UROP Posters

This study attempts to identify how attachment to social media as well as attachment to other forms of communication technology can lead to addiction to mobile devices and affect non-virtual interpersonal communication. I examined the phenomenon known as the fear of missing out, or FOMO, which can be defined as apprehension that others might be having rewarding experiences from which one is absent. Experiencing FOMO can lead to overuse of and even addiction to social media, another category I examined, because addicted individuals want to stay more up-to-date with social networks and social media is the most efficient way to …