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Articles 1621 - 1650 of 7326
Full-Text Articles in Entire DC Network
Kinetics And Inhibition Studies Of The L205r Mutant Of Camp-Dependent Protein Kinase Involved In Cushing’S Syndrome, Nicole M. Luzi, Charles E. Lyons, Darrell L. Peterson, Keith C. Ellis
Kinetics And Inhibition Studies Of The L205r Mutant Of Camp-Dependent Protein Kinase Involved In Cushing’S Syndrome, Nicole M. Luzi, Charles E. Lyons, Darrell L. Peterson, Keith C. Ellis
Medicinal Chemistry Publications
Overproduction of cortisol by the hypothalamus–pituitary–adrenal hormone system results in the clinical disorder known as Cushing's syndrome. Genomics studies have identified a key mutation (L205R) in the α‐isoform of the catalytic subunit of cAMP‐dependent protein kinase (PKACα) in adrenal adenomas of patients with adrenocorticotropic hormone‐independent Cushing's syndrome. Here, we conducted kinetics and inhibition studies on the L205R‐PKACα mutant. We have found that the L205R mutation affects the kinetics of both Kemptide and ATP as substrates, decreasing the catalytic efficiency (kcat/KM) for each substrate by 12‐fold and 4.5‐fold, respectively. We have also determined the IC …
Van Gogh Redux: “Loving Vincent” : From Quest To Pilgrimage, Games To Gravitas, Cliff Edwards
Van Gogh Redux: “Loving Vincent” : From Quest To Pilgrimage, Games To Gravitas, Cliff Edwards
World Studies Publications
A review of "Loving Vincent," the 2017 film about the artist Vincent van Gogh.
Countering The Norm, (Re)Authoring Our Lives: The Promise Counterstorytelling Holds As A Research Methodology With Lgbtq Youth And Beyond, M. Alex Wagaman, Rae Caballero Obejero, James S. Gregory
Countering The Norm, (Re)Authoring Our Lives: The Promise Counterstorytelling Holds As A Research Methodology With Lgbtq Youth And Beyond, M. Alex Wagaman, Rae Caballero Obejero, James S. Gregory
Social Work Publications
Counterstorytelling, a methodology that is rooted in critical race theory, is undergirded by principles that are beneficial to understanding the experiences of lesbian, gay, bisexual, transgender, and queer-identified (LGBTQ) young people from an intersectional perspective. Counterstorytelling holds promise as a method that creates opportunities for individual transformation and resistance to dominant narratives among young people facing systemic oppression. This article outlines the design and implementation of a counterstorytelling study with LGBTQ youth and reflects on the value and associated challenges of counterstorytelling as a participatory research method.
Autophagy-Deficient Breast Cancer Shows Early Tumor Recurrence And Escape From Dormancy, Masoud H. Manjili
Autophagy-Deficient Breast Cancer Shows Early Tumor Recurrence And Escape From Dormancy, Masoud H. Manjili
Massey Comprehensive Cancer Center Publications
Breast cancer patients who initially respond to cancer therapies often succumb to distant recurrence of the disease. It is not clear why people with the same type of breast cancer respond to treatments differently; some escape from dormancy and relapse earlier than others. In addition, some tumor clones respond to immunotherapy while others do not. We investigated how autophagy plays a role in accelerating or delaying recurrence of neu-overexpressing mouse mammary carcinoma (MMC) following adriamycin (ADR) treatment, and in affecting response to immunotherapy. We explored two strategies: 1) transient blockade of autophagy with chloroquine (CQ), which blocks fusion of autophagosomes …
Social Media Best Practices In Academic Libraries (2016), Sue Robinson, Bettina Peacemaker, Emily J. Hurst
Social Media Best Practices In Academic Libraries (2016), Sue Robinson, Bettina Peacemaker, Emily J. Hurst
VCU Libraries Faculty and Staff Data
In order to understand current trends and use of social media in libraries, VCU Libraries created and conducted an online survey using SurveyMonkey. Our approach was informed by the study of social media and public relations practice conducted by Wright and Hinson (Wright, Donald K. and Michelle Drifka Hinson. 2015. “Examining Social and Emerging Media Use in Public Relations Practice: A Ten-Year Longitudinal Analysis.” Public Relations Journal 9).
The VCU Libraries survey consisted of 22 multiple-choice, multiple-answer, and open ended questions. The survey was distributed to email discussion lists frequented by library professionals involved in management or communications. The data …
Hip Hop Pedagogy As Culturally Sustaining Pedagogy, Melanie L. Buffington, Jolie Day
Hip Hop Pedagogy As Culturally Sustaining Pedagogy, Melanie L. Buffington, Jolie Day
The Melanie Buffington Papers
This paper argues that Hip Hop Pedagogy is a version of Culturally Sustaining Pedagogy and should be a part of art education. Further, we believe that when exploring Hip Hop Pedagogy, teachers need to reference the work of Black female and non-binary artists. After an overview of Hip Hop Pedagogy and Culturally Sustaining Pedagogy, we argue that these approaches should be a consistent part of art education. Through the work of contemporary visual artist and DJ, Rozeal, we offer suggestions for art educators about how they might transition their practice to embrace some aspects of Hip Hop Pedagogy. Specifically, through …
Gerontology Theory Communicated In The Primary Grades Through Picture Books, Edward F. Ansello
Gerontology Theory Communicated In The Primary Grades Through Picture Books, Edward F. Ansello
Case Studies from Age in Action
Educational Objectives
1. To recognize children’s first literature as a means of socialization to aging and older people.
2. To identify children’s books that reflect basic principles of gerontology theory.
3. To help primary school teachers, grandparents, and others interested in human development use books and activities to capture children’s attention.
4. To identify a unit of six brief, overlapping modules, each with objectives, activities, and recommended readings.
Silver Saddles: An Equestrian Intervention For Older Adults With Dementia, Christine Jensen, Jessica Lyon, Tina Thomas, Rachel Scrivano
Silver Saddles: An Equestrian Intervention For Older Adults With Dementia, Christine Jensen, Jessica Lyon, Tina Thomas, Rachel Scrivano
Case Studies from Age in Action
Educational Objectives
1. Demonstrate the encouraging outcomes therapeutic horseback riding programs can have for older adults with memory loss.
2. Describe the importance of trained volunteers and staff at both the riding center and the long-term care community for aiding older adults with memory loss during the therapeutic riding program.
3. Showcase the research process and pilot results.
4. Highlight lessons learned and future directions for Silver Saddles.
Oral History As Inquiry: Using Digital Oral History Collections To Teach School Desegregation, Yonghee Suh, Brian J. Daugherity
Oral History As Inquiry: Using Digital Oral History Collections To Teach School Desegregation, Yonghee Suh, Brian J. Daugherity
History Publications
A body of literature in both history and history education indicates that when it comes to contemporary historical issues, oral history is one of the essential sources to investigate the past, particularly as a source for “history from below,” experiences of those who were undocumented or ill-recorded. Most of all, with new digital technologies, oral histories are more accessible than ever to those who are interested in using them in their research and teaching. This article uses the topic of school desegregation as a case study to highlight the value of oral histories as a historical methodology for studying the …
Medical Literary Messenger (Vol. 5, No. 2, Spring/Summer 2018)
Medical Literary Messenger (Vol. 5, No. 2, Spring/Summer 2018)
Medical Literary Messenger
The Essentials / Dave Morrison -- Sometimes I Pretend / Emily Pineau -- Psalm for Anorexia / Elizabeth Gauffreau -- On Harvey Dent / Bryan Walpert -- On the Level / Jane Blanchard -- Cirrhosis / Arthur Ginsberg -- Open Microphone / Stuart M. Terman -- Guest Lavatory, Beaumont Hospital, Day Five / John Jeffire -- Change of Heart / Rosie Sorenson -- Code Blue / Caroline Mosher -- Beautiful Pulses / Paul Hostovsky -- The Hospital and After / Michele Levy -- Mouth to Mouth / Charles H. Halsted -- A Meditation on Memory and Morocco / Janie Breggin …
Virginia Commonwealth University Courses [2018], Virginia Commonwealth University
Virginia Commonwealth University Courses [2018], Virginia Commonwealth University
VCU Bulletins
Listing of courses for the 2018-2019 year.
Mental Health First Aid Training For Vcu Faculty And Staff, Grace E. Harris Leadership Institute, Virginia Commonwealth University, Roy Brown, Kendra Gerlach, Cristen Jandreau, Jennifer Lee, Anne Massey, Jennifer Tennison, Peter Uetz
Mental Health First Aid Training For Vcu Faculty And Staff, Grace E. Harris Leadership Institute, Virginia Commonwealth University, Roy Brown, Kendra Gerlach, Cristen Jandreau, Jennifer Lee, Anne Massey, Jennifer Tennison, Peter Uetz
The Grace E. Harris Leadership Institute Publications
Mental Health First Aid (MHFA), an international training program, teaches participants to notice and support individuals experiencing a mental health or substance use issue and connects them to appropriate resources. While resources exist for students, this project aims to implement MHFA as a professional development opportunity for VCU faculty and staff. A successful pilot training held this summer demonstrates the need and desire for training in the VCU community. Evidence shows mental health issues lead to absenteeism, employee turnover and increased healthcare costs, costing organizations billions in recruitment that may have been avoided. Through state partnerships, trainers are available to …
Virginia Commonwealth University Commencement Program [2018], Virginia Commonwealth University
Virginia Commonwealth University Commencement Program [2018], Virginia Commonwealth University
VCU Commencement Programs
No abstract provided.
Heroic Helping: The Effects Of Priming Superhero Images On Prosociality, Daryl R. Van Tongeren, Rachel Hibbard, Megan Edwards, Evan Johnson, Kirstin Diepholz, Hanna Newbound, Andrew Shay, Russell Houpt, Athena Cairo, Jeffrey D. Green
Heroic Helping: The Effects Of Priming Superhero Images On Prosociality, Daryl R. Van Tongeren, Rachel Hibbard, Megan Edwards, Evan Johnson, Kirstin Diepholz, Hanna Newbound, Andrew Shay, Russell Houpt, Athena Cairo, Jeffrey D. Green
Psychology Publications
Two experiments examined how exposure to superhero images influences both prosociality and meaning in life. In Experiment 1 (N = 246) exposed individuals to scenes with superhero images or neutral images. Individuals primed with superhero images reported greater helping intentions relative to the control group, which, in turn, were associated with increased meaning in life (indirect effect only; no direct effect). In Experiment 2 (N = 123), individuals exposed to a superhero poster helped an experimenter in a tedious task more than those exposed to a bicycle poster, though no differences were found for meaning in life. These …
Virginia Commonwealth University Graduate Bulletin [2018], Virginia Commonwealth University
Virginia Commonwealth University Graduate Bulletin [2018], Virginia Commonwealth University
VCU Bulletins
Graduate bulletin for Virginia Commonwealth University for the academic year 2018-2019. It includes information on academic regulations, degree requirements, course offerings, faculty, academic calendar, and tuition and expenses for graduate programs.
Fostering Democratic Patriotism Through Critical Pedagogy, Hillary Parkhouse
Fostering Democratic Patriotism Through Critical Pedagogy, Hillary Parkhouse
Teaching and Learning Publications
When I was a high school US history teacher in the Washington Heights neighborhood of New York City, I sometimes wondered about the relationship between patriotism and critique of one’s nation. Specifically, I questioned just how critical students could be without becoming disaffected toward the United States. I tried to be honest with my students about the nation’s mixed record of democracy—how the country was founded on ideals of equality and yet stole land from Native Americans, kidnapped millions of Africans as part of a massive system of chattel slavery, and denied the vote to women until 1920. But I …
Medical Literary Messenger (Vol. 6, No. 1, Fall/Winter 2018)
Medical Literary Messenger (Vol. 6, No. 1, Fall/Winter 2018)
Medical Literary Messenger
Lucky / Erika Walker -- What I Fear / Kathleen Walsh Spencer -- Swimming Alone / Charles Grosel -- This Is What We Had / Marissa S. McNamara -- Study of Skull / Annalyn Welp -- Origin of an Epidemic / John Graham-Pole -- Shedding Light / Sharon Fain -- Beam of Healing: The Trigeminal Neuralgia Series / Douglas W. Johnson -- First Shower / Tracy Rothschild Lynch -- Death Sentence / Barry Peters -- The Diagnosis / Roger Hart -- Drive By / Tony Reevy -- Heart (Ink), 2017 / Laurie Wacks -- Brain (Ink), 2015 / Laurie Wacks …
Virginia Commonwealth University Undergraduate Bulletin [2018], Virginia Commonwealth University
Virginia Commonwealth University Undergraduate Bulletin [2018], Virginia Commonwealth University
VCU Bulletins
Undergraduate bulletin for Virginia Commonwealth University for the academic year 2018-2019. It includes information on academic regulations, degree requirements, course offerings, faculty, academic calendar, and tuition and expenses for undergraduate programs.
Identifying Medication Management Smartphone App Features Suitable For Young Adults With Developmental Disabilities: Delphi Consensus Study, Teresa M. Salgado, Alexa Fedrigon, Donna Riccio Omichinski, Michelle A. Meade, Karen B. Farris
Identifying Medication Management Smartphone App Features Suitable For Young Adults With Developmental Disabilities: Delphi Consensus Study, Teresa M. Salgado, Alexa Fedrigon, Donna Riccio Omichinski, Michelle A. Meade, Karen B. Farris
Pharmacotherapy and Outcomes Science Publications
Background: Smartphone apps can be a tool to facilitate independent medication management among persons with developmental disabilities. At present, multiple medication management apps exist in the market, but only 1 has been specifically designed for persons with developmental disabilities. Before initiating further app development targeting this population, input from stakeholders including persons with developmental disabilities, caregivers, and professionals regarding the most preferred features should be obtained.
Objective: The aim of this study was to identify medication management app features that are suitable to promote independence in the medication management process by young adults with developmental disabilities using a Delphi consensus …
Gender-Inclusive Library Workgroup Report, Erin White, Donna E. Coghill, M. Teresa Doherty, Liam Palmer, Steve Barkley
Gender-Inclusive Library Workgroup Report, Erin White, Donna E. Coghill, M. Teresa Doherty, Liam Palmer, Steve Barkley
VCU Libraries Task Force Reports
The Gender-Inclusive Workgroup explored how VCU Libraries can better serve trans and gender-nonconforming users and staff. The group’s recommendations cover library spaces, staff, systems, services, and culture. Key recommendations include highlighting existing all-gender restrooms; building more gender-inclusive restrooms; expanding availability of menstrual products and disposal bins; continuing support for name-of-use changes in library systems; minimizing display of legal name in library systems; offering ongoing staff training in gender-inclusive language and customer service; and encouraging staff to share pronouns. The workgroup also recommends pursuing a culture of shared learning and inclusive thinking, with a reminder that gender identity is one facet …
Virginia Dental Journal (Vol. 95, No. 2, 2018)
Virginia Dental Journal (Vol. 95, No. 2, 2018)
Virginia Dental Journal
No abstract provided.
Reception Claims In Supernatural Horror In Literature And The Course Of Weird Fiction, John Glover
Reception Claims In Supernatural Horror In Literature And The Course Of Weird Fiction, John Glover
VCU Libraries Faculty and Staff Publications
This chapter explores H. P. Lovecraft's essay "Supernatural Horror in Literature," considering the ways in which Lovecraft attempted to construct favorable conditions for the reception of his own work. The writing of the essay was a pivotal moment in Lovecraft's career and authorial self-fashioning. Both it and he went on to influence the development of weird fiction in Lovecraft's lifetime and subsequently, lasting well into the current period of reevaluation of the author's legacy and person.
Ramerican Political Science Review (Vol. 3, 2018)
Ramerican Political Science Review (Vol. 3, 2018)
Ramerican Political Science Review
Letter from the Department of Political Science -- To What Extent Will Peaceful Korean Reunification Impact Both the North and South Korean Economies? / Hayne Noh -- The Impact of Gender Mainstreaming on Sexual Exploitation and Abuse by UN Peacekeepers / Katilyn Thomas -- Bangladesh and Its Quest to Become A Middle Income Country: An Evaluation of the Relationship Between Higher Education in Women and Economic Development / Thomas Fratkin -- Framing Bias and Identity Characteristics in the Portrayal of Terrorists in American News Media / Saffeya Ahmed -- The “Drone Memo” and the Targeted Killing of Anwar al-Aulaqi / …
Virginia Dental Journal (Vol. 95, No. 1, 2018)
Virginia Dental Journal (Vol. 95, No. 1, 2018)
Virginia Dental Journal
No abstract provided.
Radical Chemistry In A Femtosecond Laser Plasma: Photochemical Reduction Of Ag+ In Liquid Ammonia Solution, Victoria K. Meader, Mallory G. John, Laysa M. Frias Batista, Syeda Ahsan, Katharine M. Tibbetts
Radical Chemistry In A Femtosecond Laser Plasma: Photochemical Reduction Of Ag+ In Liquid Ammonia Solution, Victoria K. Meader, Mallory G. John, Laysa M. Frias Batista, Syeda Ahsan, Katharine M. Tibbetts
Chemistry Publications
Plasmas with dense concentrations of reactive species such as hydrated electrons and hydroxyl radicals are generated from focusing intense femtosecond laser pulses into aqueous media. These radical species can reduce metal ions such as Au3+ to form metal nanoparticles (NPs). However, the formation of H2O2 by the recombination of hydroxyl radicals inhibits the reduction of Ag+ through back-oxidation. This work has explored the control of hydroxyl radical chemistry in a femtosecond laser-generated plasma through the addition of liquid ammonia. The irradiation of liquid ammonia solutions resulted in a reaction between NH3 and OH·, forming peroxynitrite and ONOO−, and significantly reducing …
Hours Lost To Planned And Unplanned Dental Visits Among Us Adults, Uma Kelekar, Shillpa Naavaal
Hours Lost To Planned And Unplanned Dental Visits Among Us Adults, Uma Kelekar, Shillpa Naavaal
Dental Public Health and Policy Publications
Introduction
Poor oral health is associated with lost hours at work or school, which may affect a person’s productivity. The objective of our study was to estimate work or school hours lost to dental visits among adults aged 18 and older by the types of visits (emergency or unplanned; routine, planned, or orthodontic; or cosmetic) and to determine the factors associated with hours lost.
Methods
We used the most recent Oral Health Supplement data, from the 2008 National Health Interview Survey (NHIS), to estimate the total hours lost at work or school for dental visits among adults in the United …
Estimating The Cost Of School Sealant Programs With Minimal Data, Susan O. Griffin, Kari Jones, Shillpa Naavaal, Joan M. O'Connell, Christina Demopoulos, Dawn Arlotta
Estimating The Cost Of School Sealant Programs With Minimal Data, Susan O. Griffin, Kari Jones, Shillpa Naavaal, Joan M. O'Connell, Christina Demopoulos, Dawn Arlotta
Dental Public Health and Policy Publications
Objective: Develop methodology to estimate the annual cost of resources used by school sealant programs (SSPs) and demonstrate its use.
Methods: We used existing literature and expert opinion to identify SSP cost components and the most appropriate units for their measurement (e.g., per operator) and collection frequency (e.g., per day). For equipment and reusable instruments, costs were sufficiently homogenous across SSPs that we could provide default per unit cost estimates (2016 US$) that SSPs can use in lieu of collecting their own data. We also provide default costs for supply items such that SSPs can estimate total supply costs with …