Digital Commons Network^™

Pwatem: An Anthology Of Literature And Art (2019)

Pwatem (Poictesme), 2006-

Pwatem is an anthology of literature and art from undergraduate students at Virginia Commonwealth University. Pwatem publishes poetry, prose and art of all kinds from talented undergraduate students of all majors.

The Compass, Summer 2019

The Compass, 2018-

The Compass is an annual orientation guide for VCU students produced by the Student Media Collective in the VCU Student Media Centered. The guide is distributed physically during summer orientation sessions for new and transfer students. The publication includes short articles, illustrations, letters of welcome from students and administrators, comics, and advertisements from VCU and Richmond organizations.

Amendment Literary And Art Journal + Medical Literary Messenger: Ablation (2019)

Amendment, 2004-

A zine companion to the Amendment and Medical Literary Messenger.

Rabble: A Chapbook Companion To Pwatem (2019)

Rabble, 2014-

Rabble is a companion chapbook publication to the magazine Pwatem. From the preface of most issues: "'Tell the rabble my name is Cabell."- James Branch Cabell to his editor, to help people learn how to pronounce his name. Cabell used the word derogatively but we are taking it back. These pages will showcase the writing and illustrations of our rabble-the ordinary students of VCU."

Understanding Effectiveness Of A Diverse Board In The Nonprofit Sector: The Role Of Board Inclusion & Critical Mass Of The Diverse Board Members, Suparna Dutta

Theses and Dissertations

Using rated responses from nonprofit CEOs who participated in the 2016 BoardSource national survey, this study investigates whether nonprofit board inclusive behavior or board inclusive practices are positively correlated with nonprofit board effectiveness. It further examines whether a critical mass of racial and ethnic minority or women board members may moderate the relationship stated above. To answer these questions, the study tested six hypotheses using principal component analysis, followed by hierarchical regression analysis, and found no evidence of statistical significance in main or moderator effects. The study recommends that policymakers should frame policies that ensure mandatory quotas for women and …

The Role Of Irf1 In The Brain And In Adaptive Responses Of Astrocytes, Andrew Hoskins

Theses and Dissertations

In neurodegenerative diseases, the CNS becomes inflamed through activation of pathways, including the NF-B pathway. Some of the therapies for those diseases target neuroinflammatory pathways. Here, we explore the mechanisms for the upregulation of a subset of genes following a restimulation of the NF-B pathway. We discover that this upregulation occurs independent of IRF1 expression and type 1 interferon signaling. A knockdown of IRF1 using siRNA and an inhibition of JAK proteins using inhibitor AG490 both had no effect on priming. A secreted factor was found to upregulate the expression of both this subset of genes and genes encoding pro-inflammatory …

Perception Of Patient Cooperation Among Dentist, Guardian, And Child, Cole A. Staines Dds

Theses and Dissertations

Purpose: Evaluate behavior assessment and agreement among dentist, guardian, and child. Evaluate child behavior by appointment type.

Methods: Patients recruited from the pediatric dental department at Virginia Commonwealth University for this convenience sample. Inclusion criteria: patients presenting for clinical exams and/or restorative treatment without the use of advanced behavior guidance between August 29, 2018, and March 7, 2019; ages 4-12-years-old; and scheduled with a single clinician. Appointments were stratified by difficulty. Behavior was assessed by dentist and caregiver using the Frankl Scale. Patient self-assessed cooperation using an age-appropriate modified Frankl Scale, developed for this study. Agreement assessed among the 3 …

The Nail That Sticks Up Isn't Always Hammered Down: Women, Employment Discrimination, And Litigiousness In Japan, Kristen Luck

Theses and Dissertations

Much recent scholarship is devoted to projecting Japan’s future and analyzing its prospects as a global power. After two decades of economic stagnation, alarming demographic trends, and the 3/11 triple disaster, some scholars argue that Japan is grappling with an era of precarity, marked with instability and anxiety. Prime Minister Shinzo Abe returned to office in 2012, promoting his economic reform policy, “Abenomics” and within the third “arrow" of this approach targeting structural reforms, he promoted “womenomics”, a term coined by Kathy Matsui of Goldman-Sachs. Prime Minister Abe’s objective is to create a society where "women can shine” and women …

A Thesis Is A Product Is A Tracking, Yixue Li

Theses and Dissertations

In this work, I discuss how global products/ identities are made, transported and consumed, and the inevitable ‘mis-’ in acts of transmission. This research ranges from the miscommunication in languages and linguistics, to the gap between production and consumption. I investigate how things and humans are misread, mispronounced, misfit and mistranslated when they traverse social and cultural borders, arriving at a place in between languages, holding on to and letting go of things that are familiar to neither and both cultures. This work explores diverse media such as publications, videos and installations, and examines how they maybe used to address …

Mother/Artist/Teacher: The Labor Of Becoming, Miranda L. Clayton

Theses and Dissertations

This paper explores possible applications of the experiential knowledge of motherhood in the field of art education through self-portraiture, a methodology which blends a/r/tography with elements of portraiture. A review of relevant literature situates the study within the scope of mothering pedagogy and arts-based research. Employing artistic practice and anecdotal journaling as the primary methods of inquiry, the researcher examines her experiences as a mother in a preservice art education program and the intersections of her roles as mother/artist/teacher. The researcher identifies resonant metaphors, including labor, separation, the umbilical cord, circles, the ovum, and pretending; offers parallels between mothering and …

Examination Of Strain-Dependent Differences In S. Sanguinis Virulence And Growth, Shannon Baker

Theses and Dissertations

Streptococcus sanguinis, an abundant and benign inhabitant of the oral cavity, is an important etiologic agent of infective endocarditis, particularly in people with pre-disposing cardiac valvular damage. Although commonly isolated from patients with IE, little is known about the factors that make any particular S. sanguinis isolate more virulent than another or, indeed, whether significant differences in virulence exist among isolates. To investigate the virulence of multiple isolates, a variation of the Bar-seq (barcode sequencing) method was employed. A conserved chromosomal site was identified for subsequent insertion of a barcode identifier, unique for each strain. Barcode insertion did not …

Enhanced Proteomics Resolves Kcc2 As A Novel Therapeutic Target For Traumatic Brain Injury, Pavel N. Lizhnyak

Theses and Dissertations

The development of traumatic brain injury (TBI) therapeutics and effective translation to clinic remains stubbornly elusive despite the high prevalence of TBI within the United States and across the globe. Interventions must be devised around testable targets, appropriately timed to intercede on secondary results. Here, we have utilized temporal neuroproteomics as an ideal approach to inform on the complex biochemical processing in order to address the well-recognized temporal evolution of TBI pathobiology and interrogate a novel therapeutic target in a mild-moderate rat Controlled Cortical Impact (CCI) within perilesioned somatosensory cortex. First, our findings revealed 2047 proteins significantly impacted within the …

Arab Americanesque, Hannah W. Shaban

Theses and Dissertations

Culture, as defined by Edward Said, is a concept of identity selectively curated through imperialism. Through my ceramic practice, I explore what constitutes my cultural identity as a first generation Arab American. My work, primarily influenced by family narrative was initially expressed through investigations in the figure and viewer relationships with my sculpted figures. As my research progressed into Western Imperialism, I began noticing extensive evidence of colonialism’s lasting effects, especially within Western consumer markets. Interest in the writings of Said, works by French Orientalist painters, family memory, and a general displeasure with the plethora of Middle Eastern design used …

Bending Educational Reality, Mariam Rafehi

Theses and Dissertations

Virtual reality (VR), an emergent technology, affords experiential content delivery in education by evoking emotive responses in users, which can be prohibitive via traditional media. This thesis explores VR for the development of grit – passion and perseverance, which are essential characteristics in education and long-term success. The research proposes design strategies to stimulate senses for emotional engagement and a physiological response. In the project, two interactive environments position the user in emotional states to build passion and perseverance. To develop passion, the virtual world is designed to engage in creativity using 3D-spatial audio and visual effects. In contrast, to …

Characterization Of The Novel Interaction Between Neisseria Gonorrhoeae Tdfj And Its Human Ligand S100a7, Stavros Maurakis

Theses and Dissertations

Neisseria gonorrhoeae is an obligate human pathogen that causes the common STI gonorrhea, which presents a growing threat to global health. The WHO estimated 78 million new cases of gonorrhea worldwide in 2017, with estimates of 820,000 new cases in the United States alone according to the CDC. High-frequency phase and antigenic variation inherent in N. gonorrhoeae, coupled with its natural ability to rapidly acquire and stably integrate antimicrobial resistance factors into its genome, have culminated in an infection against which there is no effective vaccine, and for which the list of viable therapeutic options is quickly shrinking. Moreover, no …

Metallic Systems At The Nano And Micro Scale: Bimetallic Nanoparticles As Catalysts And Mcraly Bond Coats In Thermal Barrier Coatings, Kenneth Kane

Theses and Dissertations

The dissertation is split into two parts. The first part will be focused on changes in material properties found at the nanoscale, as miscibility and electronic structure can change significantly with size. The formation of classically-immiscible bimetallic nanoparticles (BNPs) becomes favorable at the nanoscale and novel catalytic properties can emerge from the bimetallic alloying. The formation of alloyed and non-alloyed BNPs is achieved through pulse laser ablation (PLA) and a significant increase in catalytic activity is observed for both. Recently discovered, the increased activity in the non-alloyed BNPs, deemed multicomponent photocatalysis, is examined and the proposed mechanism discussed. The second …

Impacts Of Gender-Based Violence And Harassment On Graduate Student Academic Functioning, Jennifer W. Underwood

Theses and Dissertations

Researchers and practitioners have increasingly focused on institutional responses to campus gender-based violence/harassment, yet they have paid far less attention to graduate student experiences than to undergraduate student experiences. Graduate students operate in a different context from undergraduates, and therefore specific knowledge of gender-based violence/harassment in the lives of graduate students is needed. The purpose of this exploratory, nonexperimental study was to better understand the prevalence of adult gender-based violence/harassment and adverse childhood experiences (ACEs) among graduate students, as well as to understand the relationship between those experiences and participants’ mental health and academic functioning. The study’s theoretical framework combined …

Genetic And Environmental Factors Influence Drosophila Ethanol Sedation, Rebecca E. Schmitt

Theses and Dissertations

Alcohol use disorder is a global health issue that affects a significant portion of the population, with affects including both negative mental and physical consequences. Currently, there are few treatment options available to those who suffer from alcohol use disorder, alcohol abuse, or alcohol dependence. Identifying candidate genes or environmental influences would therefore improve the means for possible treatments or identification of those people at risk for alcohol use disorder. Previous studies in humans have demonstrated an inverse association between initial sensitivity and risk for alcohol abuse. This connection allows investigators, and our laboratory, to investigate genetic and environmental factors …

Finpathlight: Framework For An Ontology-Based, Multiagent, Hybrid Recommender System Designed To Increase Consumer Financial Capability, Lawrence Bunnell

Theses and Dissertations

This study is a design science research (DSR) project in which a description of the development and evaluation process for several novel technological artifacts will be communicated. Specifically, this study will establish: 1) an ontology of recommender systems issues, 2) an ontology of financial capability goals, and 3) a framework for a Personal Financial Recommender System (PFRS) application designed to improve user financial capability, called FinPathlight. The impetus for the RecSys Issues Ontology is to address a gap in the literature by providing researchers with a comprehensive knowledge classification of the issues and limitations inherent to recommender systems research. …

Parallel Pattern: A Familial Legacy Of Care, Diana Antohe

Theses and Dissertations

My work revolves around exploring identity of the in-between, occupying the Venn diagram middle of two cultures. As a Romanian-born, American-raised artist, I want to preserve and broadcast links to the cultures of my upbringing and birthplace. In attempts to ground and define my own “in-between” identity, I look to my parents and grandparents for cues on how they made home for themselves wherever they went, reflecting their experiences with voluntary and involuntary displacement. This text connects the research and influential family practices that shaped its companion exhibition, ranging from the role of portability in emotional transnationalism to the lasting …

At The Table; An Investigation Of How Growing, Cooking, And Sharing Food Together Can Bring A Wealth Of Benefits, Angeline M. Troilo

Theses and Dissertations

MOTIVATION: The value of family mealtime has been well documented by decades of academic research. Children from families, (regardless of race, class or income), that routinely sit down to a meal together, suffer less depression, obesity and substance abuse. They also stay healthier and do better in school (Benefits 2018). There are nutrition, health, social, and mental benefits to eating with others. Research has shown that people eat more fruits and vegetables and other nutrient-rich foods when they share a meal with others. They also drink less soda and eat less fried foods (Benefits 2018). Eating meals together teaches children …

A Sacred Gift: Rebalancing Our Relationship With Water, Noora Naser Melhim

Theses and Dissertations

In the Middle East, and specifically Qatar, water has significant cultural history and preciousness as a commodity. Today, the rapid economic development has resulted in a disconnection from the past leading to subconscious overconsumption of water.

This thesis investigates water from the context of cultural relevance, by examining systems of distribution before and after the discovery of oil. It reinterprets the materiality of the traditional ceramic vessels used to contain and preserve water with the intention of using the natural properties of clay, such as cooling and filtering, to produce new artifacts. The intent of this research is to critically …

(And I Can't Stress This Enough) In My Mouth: Extradiegetic Affect As Material, C. Klockner

Theses and Dissertations

(and i can’t stress this enough) in my mouth: Extradiegetic Affect as Material is a non-linear exploration into the structures of feeling that exist in relation to cinema in its role as a technology for generating subjectivity. In the development of this research, a proposal of cinema’s likeness to the ecological circulation of microplastics is drawn in order to illustrate cinema’s materiality and nearly invisible ubiquity. The notion of extradiegetic affect is outlined as a post-cinematic condition in which lived experience becomes secondary to cinematic representation and which, simultaneously, becomes directly shaped by engaging with these representations.

...An Already Dreamed State Already Dreaming State Already…, Francheska Alcantara

Theses and Dissertations

A compendium of horizontality through the means of theory, facts, fictions, questions and other ruminations on the Caribbean and the diasporic experience.

An Enzymology And Inhibition Study Of A Camp-Dependent Protein Kinase Linked To Acth-Independent Cushing's Syndrome, Nicole Luzi

Theses and Dissertations

Cyclic-AMP dependent protein kinase (PKA) is a key intracellular signal transduction kinase that is modulated by G_s- and G_i-coupled GPCRs. Under normal physiological conditions, PKA exists as an inactive holoenzyme made up of two catalytic subunits and two regulatory subunits. Upon cAMP binding to the regulatory subunits, the catalytic subunits (PKACa) are released to perform various downstream phosphorylation events. However, aberrant PKA activation can cause various diseases including Cushing’s Syndrome, which is an endocrine disorder caused by the overproduction of cortisol by the hypothalamus-pituitary-adrenal hormone system. This disorder can be caused by pituitary adenomas that release …

William Bernard Cooke, George Cooke, And J.M.W. Turner: Business Of The Topographical Print Series, Saskia C. Turpijn

Theses and Dissertations

The organization of eighteenth and nineteenth-century British printmaking and publishing was based on economic principles and occurred in the collaborative sphere of the engraver’s studio. Print designers, engravers, printers, and publishers formed a professional network that operated on economic principles, publishing prints that served to generate income for its participants. These ventures faced great challenges in the lengthy and laborious processes of engraving and publishing, and in financing the project for the duration of that time.

This project examines the economic structure of early nineteenth-century prints. Using comprehensive accounting records, it analyzes two well-known topographical print series. The profitable Southern …

Planning An Inclusive Entrepreneurial Ecosystem In Norfolk Virginia, Matthew A. Cline

Master of Urban and Regional Planning Capstone Projects

Provides an overview of Norfolk’s emerging entrepreneurial ecosystem and challenges associated with its disadvantaged entrepreneurs. Presents policy recommendations in creating more equitable environment for these small business ventures.

Residential Fire Impacts On Richmond, Virginia: A Plan For Identifying And Educating Our Most Vulnerable Communities, Jennifer L. Tillett

Master of Urban and Regional Planning Capstone Projects

In 2017, 1.3 million fires in the U.S. caused 3,400 deaths, 14,600 injuries, and $23 billion in loss. Vulnerable populations are less resilient due to their lack of adequate access to financial, medical, and community resources as well as their propensity to reside in substandard housing. This plan studies the impacts of Richmond’s residential fires (2015-2017) on vulnerable communities within the city. Its purpose is to provide an understanding of where fires occurred in vulnerable communities and to recommend actions for prevention education.

The plan is divided into six sections: Introduction, Background, Methodology, Findings, Recommendations, and Implementation. A Social Vulnerability …

Saving The Libby Hill Viewshed: Preserving And Enhancing One Of Richmond’S Greatest Assets, Christopher J. Mcnamara

Master of Urban and Regional Planning Capstone Projects

The view from Libby Hill Park in Richmond's Church Hill neighborhood has been identified as an endangered view, and the possibility of new development changing this view has increased in recent years. This plan explores what this view means to the identity of the neighborhood and the city and identifies ways to preserve the view while promoting development. The plan also identifies ways to make the park more accessible and open to all residents to increase its value to the city of Richmond, VA.

Metaproteomic Investigation Of The Vaginal Microbiome In Pregnancy, Zaneera Hassan

Theses and Dissertations

The development of early diagnostics and prevention strategies for preterm birth is an important global health challenge with the potential to impact over 15 million children annually, by improving health outcomes and reducing economic burden. Advances in microbial sequencing technology have opened the door to 16S rRNA gene survey, whole metagenomics, and whole transcriptomics, providing molecular evidence that the composition of the vaginal microbiome affects pregnancy outcomes in women, particularly those of African descent. A current gap in our molecular level understanding of the vaginal microbiome as it relates to healthy pregnancies is the metaproteome which comprises proteins from both …