Digital Commons Network^™

The Effects Of Exosomes On The Regeneration Of Rat Calvaria, Jill T. Beitz

Theses and Dissertations

Periodontal disease is a bacterial induced chronic inflammatory condition that occurs in a susceptible host, affecting the teeth, gingiva, periodontal ligament, and alveolar bone. The resultant pathological bone defects often require surgical intervention, with the ultimate goal being regeneration of the periodontium through the application of grafting materials and biologics. Mesenchymal stem cells (MSCs) show great potential in regenerative medicine for their ability to enhance cell proliferation and differentiation, increase angiogenesis, and modulate the immune response. Stem cell-derived by-products, known as exosomes are a specific class of lipid-membrane-bound extracellular vesicles that are proliferative and chemotactic, are able to inhibit cytokine …

Cyberbullying: School Administrators' Perceptions Of Law And Prevalence, And Their Roles In Prevention, Intervention And Discipline, Suzan Gragg Denby

Theses and Dissertations

This study was aimed at investigating secondary school administrators’ experiences with and their perceptions of cyberbullying, as well as their intervention and prevention procedures. As technology has become ubiquitous in our society, students’ use has increased and impacted the school environment. Given the potential for cyberbullying and the negative effects of such, schools harbor the responsibility to prevent and intervene in such occurrences. This can be a tricky process.

This study included 12 administrators of secondary schools across eight school divisions in Virginia. Through an interview process, administrators spoke of their experiences with technology and cyberbullying incidents, and how they …

The Intersection Of Social Stress, Mental Well-Being, And Sexual Health Among Black Women In Emerging Adulthood, Brandi Galloway

Theses and Dissertations

With an estimated 37,000 new HIV infections each year, HIV continues to be a major public health concern. HIV affects some populations more than others. Young Black women, in particular, are disproportionately affected by HIV. While being a woman does not typically increase a person’s HIV risk, being Black and being a woman does.

Data indicate that individual-level factors do not fully address the differences in HIV and STIs between Black emerging adult women and their White counterparts. Thus, it is critical to better understand contextual factors such as social stress and mental-wellbeing which might better account for these disparities. …

Changing Landscapes: Perspectives Of Young African American Women Of Population-Wide Testing For Hereditary Breast Cancer Mutations, Alesha Henderson

Theses and Dissertations

Young African American women continue to die from breast cancer at higher rates than White women. In an effort to promote breast cancer prevention, population-wide testing (PWT) for all women in the U.S. starting at age 30 is a potential future initiative that is garnering a lot of attention. However, African American women currently utilize genetic testing for hereditary breast cancer at lower rates than White women. Therefore, if young African American women are not prioritized in a future roll out of PWT, then existing breast cancer and genetic testing disparities will likely continue to widen. The purpose of this …

Swipe Right For Condoms And Testing: Differences In High-Risk Sexual Behavior And Sexual Health Beliefs Among Dating App Users Compared To Non-App Users, Shelby A. Smout

Theses and Dissertations

Millions of Americans are currently using smartphone dating applications (apps) to socialize and meet with others. In some cases, app-based conversations lead to sexual interactions. Previous research examining the relationship between the use of dating apps and sexual behaviors has found that individuals who use dating apps and meet with partners from the app are more likely to engage in high-risk sexual behaviors such as having multiple partners and inconsistent condom use. Individuals between the ages of 18 and 24 are the group most likely to be using dating apps compared to other age groups and are a high-risk group …

Entitled Versus Untitled, Johana Nasreen

Theses and Dissertations

Social hierarchy across class divisions in Qatar is evident in clothing apparel. Materiality, objects and form act as powerful signifiers relative to an individual’s social belonging. Our perception and identification of these elements is driven by our own pre-existing assumptions and position within Qatar’s social stratification. We interpret social status and identity through symbolic representation.

Construction site materials are demonstrative of individuals working on the sites and their social status, just as the Birkin bag becomes emblematic of the women’s position within the social hierarchy. This thesis project utilizes hybridization of material and form as a primary mode for translating …

A Phenomenological Study Of Nonbinary Resilience And Mental Health, Calvin J. Hall Iii

Theses and Dissertations

Nonbinary individuals, or those who do not exclusively identify with a male or female gender, have gained increasing recognition and representation within the past ten years. Despite these steps forward, nonbinary individuals still experience higher rates of sexual assault, police brutality/harassment, job-related discrimination, and erasure when compared to binary transgender individuals, or gender-diverse individuals who exclusively identify as male or female. These disparities in violence, discriminatory practices, and erasure have been linked to exceptionally high rates of depression and anxiety in nonbinary people within the U.S. Thus, efforts to improve nonbinary mental health are critically needed. Previous research finds that …

Social Learning Theory And Digital Piracy: Explaining Uploading Behaviors Of Digital Pirates, Cydney J. Lowenstein

Theses and Dissertations

Digital piracy has received significant attention in criminological research but almost no studies have explored illegal uploading and how it may differ from illegal downloading. It is important to examine what theories can explain illegal uploading behaviors and their related factors to develop more effective policies to address digital piracy. This dissertation examined whether Akers’ (1998) social learning theory could explain engagement in digital piracy, both illegal downloading and uploading behavior. Additionally, this research examined the relationship between reciprocity and digital piracy. Questionnaires were administered to 398 university students and 315 visitors to several online communities using a combination of …

Self-Efficacy Of Endorsed And Nonendorsed Elementary Teachers Of Gifted Students In Stem Education, Lianna L. Moss-Everhart

Theses and Dissertations

This study compared elementary endorsed and nonendorsed teachers of gifted students in science, mathematics, and STEM self-efficacy as well as self-reported use of STEM instructional strategies in central Virginia. The survey, adapted from the T-STEM survey by the Friday Institute at NC State University, focused on self-efficacy and use of STEM instructional strategies. ANOVAs, univariate linear analyses, were conducted on 39 responses to compare teachers’ self-efficacy and use of STEM instructional strategies. ANCOVA and moderated regressions were used to compare the groups of teachers while controlling for the variables of grade level, years of experience, and recent STEM training. Multiple …

Culturally-Relevant Factors That Influence Healthy Eating Among African American College Students, Danyel Smith

Theses and Dissertations

Obesity is a national epidemic in the US, disproportionately affecting African Americans, such that the obesity prevalence in African Americans (49.6%) surpassed the national prevalence (42.4%) in 2018. Those same disparities exist at the collegiate level, such that 27.4% of a sample of African Americans college students had obesity, surpassing the national prevalence of obesity (12.1%) in 2018. Diet, an important driver of obesity, is influenced by several psychological, social, and environmental factors. However, cultural factors influencing diet are understudied among African American college students. The overarching goal of the current study was to identify culturally-relevant factors that promote healthy …

Comparing Parent-Report And Performance-Based Measures Of Vestibular Processing, Elisha D. Chambers

Theses and Dissertations

Abstract

Comparing Parent-report and Performance-based Measures of Vestibular Processing

By Elisha Chambers, MS. OTR/L

A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy at Virginia Commonwealth University

Virginia Commonwealth University, 2020

Major Director: Stacey Reynolds, Ph.D OTR/L

Associate Professor, Department of Occupational Therapy

In the field of occupational therapy, there is a need to explore the relationship between performance based-measures and parent-report measures of vestibular functioning because thorough assessment sets the foundation for effective intervention. Time constraints, child distractibility, and limited participation are all issues that pediatric occupational therapists face during evaluations. It …

Impact Of A Culturally-Relevant Support Program And Latinx Adolescents' Help Seeking Services: An Academic-Latinx Community Service Partnership To Enhance Culturally Responsive Services For Latinx Immigrant Youth., Lisa S. Fuentes

Theses and Dissertations

Latinxs, in general, report logistical barriers that contribute to utilizing fewer healthcare services and/or not knowing how to navigate the healthcare system. In addition to underutilizing healthcare services, Latinx immigrant youth also report higher levels of negative attitudes towards mental health. However, little is still known regarding factors that impact these attitudes with Latinx immigrant youth, as well as the community support efforts that are available to this specific group. Using a semi-structured interview on 12 Latinx immigrant youth, this master’s thesis explored: (1) the attitudes towards mental health, (2) attitudes towards mental health services, (3) and the experiences of …

Discerning The Spectroscopic Properties And Chemical Reactivity Of Bioinspired Metallocomplexes, Ashley K. Forney

Theses and Dissertations

In Nature, metalloenzymes catalyze a variety of thermodynamically demanding reactions with remarkable performance under mild, physiological conditions. This innate ability is a driving force for the development of nature inspired, synthetic analogues that are robust and can catalyze a variety of organic transformations. This work involves the successful syntheses of four coordinate, bioinspired complexes, [M^II(n-DOB)] (M = Ni, Co, and Cu; n = 12 and 13), which have been characterized by NMR, ESI-MS, UV/Vis, EPR, and CV. Spectroscopic evidence presents the generation of reactive metal-(di)oxygen species that display amphoteric reaction behavior, making these rarities among inorganic oxidants. These …

University Hackathons: Managerialism, Gamification, And The Foreclosure Of Creativity, Anthony L. Clary

Theses and Dissertations

This research presents a generative critique of hackathon events held in the contemporary research university. Through the analysis of cultural imaginaries and embedded techno-political forms, it works toward an assessment of whether these events support, foreclose, or redirect ideas of the future that might otherwise challenge technocratic, accumulatory, and/or hierarchal organization. Informed by institutional histories and firsthand field research at events, dynamics of entrepreneurialism, gamification, and techno-solutionism are extrapolated and problematized. Ultimately, this research draws on a historical materialist approach to understanding how and why hackathon events have flourished in the university setting. Corroborating recent theories of platform capitalism, vectoralism, …

Mother Is How I Got Down Pat, Kyrae Dawaun

Theses and Dissertations

This essay gathers concepts of matriarchal studies, theatre and hospitality in thinking beyond the contemporary venue of painting. Recognizing the limits of fine arts, as it is today, a product of a patriarchal, capitalistic societal structure, in its service to an inclusive, public sphere, my work is insistent on the value of installation. Accessibility to space (the art space), language, and the right to politics are goals inspiring the evolved features in my studio practice. The use of word is central in my study of our human behaviors as they can be best modeled according to the appreciation of mother(ing). …

Exploring The Creation Of Immersive And Responsive Spaces For Interrelationship Through The Concept Of Playfulness, Yonghun Jung

Theses and Dissertations

The COVID-19 pandemic that began in early 2020 is causing serious damage to many countries. As of May, the number of confirmed patients worldwide is at 3.35 million and the death toll stands at 239,000 people. As a way to prevent the pandemic, most countries encourage people to keep social or physical distance and self-quarantine. According to the U.S. Centers for Disease Control and Prevention, they recommend that people stay at least six feet away from each other and the South Korean government also recommend keeping their distance from each other at least two meters.

Because of the current situation, …

Detection Of Biomolecules Via Ocp Measurements Using Npg Electrodes, Borkat Ullah

Theses and Dissertations

In sensing application nanoporous gold (NPG) has attracted much attention. NPG is prepared by dealloying Au:Ag alloys. Characterization was done using scanning electron microscopy (SEM), X-ray photoelectron spectroscopy (XPS), and cyclic voltammetry (CV). In this work, the open circuit potential (OCP) of ferricyanide, cysteine, uric acid, and ascorbic acid was measured in phosphate buffer solution (PBS) and biofouling solution containing bovine serum albumin (BSA) at pH 7.4. OCP measurement has been hindered due to biofouling and surface passivation on the metal electrodes. By the use of the NPG electrodes, electrochemical activity can be maintained. From the OCP measurement of cysteine, …

I Hope My Black Skin Don't Dirt This White Tuxedo, Luis A. Vasquez La Roche

Theses and Dissertations

I Hope My Black Skin Don't Dirt This White Tuxedo is a series of works--sculpture, installations, and performances--that explore themes of shame, failure, commodity, ephemerality, ritual, resilience, erasure, race, and death. The research and interest in these themes stem from a page of the Trinidad and Tobago Slave Registry. I use the research that surrounds this document to highlight different moments in history, in my personal life, and to imagine near futures.

Port To World, Samuel M. Brown

Theses and Dissertations

Among those that are ill for long periods, there is often a mistrust created not only in one’s own body but in the institution that promises a cure to the malady. Often this stems naturally from the dogma of the institution paired with one’s desire for wellness, for the institution's goals are many besides the overall health of the patient. Even when a patient is cured of an ailment, this is often just the first step in the actual healing process. The body can quickly change, and the mind takes time to catch up with the body's condition. My work …

Paul By Paul By Paul, Paul Finch

Theses and Dissertations

In 2020 flamboyant fashion is associated with queer performativity. Psychologist Alan Downs and queer theorist madison moore understand this to be a response to a culture that is hostile to sexual behaviour and gender expression that falls outside a rigid binary. I study the history of flamboyant aesthetics and camp sensibilities from an intersectional perspective, and locate designers and artists who have produced clothes in ways that materialize the political implications of fashion. As a studio-based artist, I employ traditional sewing techniques, digital technologies, and performance to create clothes and new media works that demonstrate a circular understanding of time, …

Moving Parts, Andrew Lowrie

Theses and Dissertations

Material bodies, human and non-human, exist in a constant state of doing and undoing. As bodies change over time, so too do the objects they wear. In this way, a jewelry object is never finished and is constantly being made. In contemporary art practice, this is described as relational ontology by Amelia Jones, who reaches this terminology through the eco-political writings of Jane Bennett and Karen Barad. Through this framework we are able to understand the way artists like Gabriel Orozco and Helen Carnac resist the notion of a finished object or artwork. By engaging with the ways that process …

...And Yet The Devil Exists, John Hee Taek Chae

Theses and Dissertations

...And Yet the Devil Exists is a project that explores the ways in which ideology determines reality. It is an installation that plots and connects the historical and personal narratives that have defined my sense of identity–narratives in which perceptions of reality shatter, mutate, or hybridize when confronted with power, opportunity, or coercion. The installation component of the project consists of three parts. The first is an infrastructure made of wooden beams upon which paintings and images are installed; I call this the lantern. In the center of this is a round table on top of which is a nonsensical …

Relationship Of Demographic Characteristics Of Occupational And Physical Therapists Towards Their Knowledge And Attitude On Person-Centered Care In Skilled Nursing Facilities, Sadashiv R. Aggarwal

Theses and Dissertations

The study aimed to assess the relationship of specific demographic characteristics of occupational (OTs) and physical therapists (PTs) with their knowledge and attitudes towards principles of Person-Centered Care (PCC) in skilled nursing facilities (SNFs). The study further examined if knowledge and/or attitudinal differences exist between OTs and PTs towards PCC. The proposed descriptive study used the Person-Centered Care theory, which is a holistic (bio-psychosocial-spiritual) health care delivery approach. PCC delivers services that are respectful and individualized, allowing negotiation of care, and offering choice through a therapeutic relationship where persons receiving care are empowered to be involved in health decisions at …

See As One, Min Haeng Kang

Theses and Dissertations

Everything that exists in the world is made from “nature.” Humans who initially coexisted with nature began to distinguish themselves from what is human and what is not. Unlike past systems that used to reuse all materials, Society so far has focused on maximizing economic profits along with advancing technology. As a result, the nature of the earth is being irrevocably destroyed, and I think the basis for this lies in the distinctions made between the human and the non-human.

I am always seeking to be in a state where I do not have an atman, like the Buddhist concept …

Jazz, Improvisation & The Importance Of Collaboration, Laurie Marcotte

Theses and Dissertations

Project Statement

As one of the least popular, yet highly influential and pervasive, musical genres of modern times, jazz will help inspire impressionable high school aged students in cultivating individual expression and collaboration through an environment of musical and social interaction. The project is designed to be a safe haven for these students where the ambiance intends to promote a sense of self-worth, security, and curiosity through the engagement of jazz music.

Concept Statement

The project celebrates harmony and individual expression through the improvisational and collaborative efforts of jazz music.

Motivation

It is commonly accepted that music education has a …

Spooky Stuff, Petra A. Szilagyi

Theses and Dissertations

A real imaginal exploration of the aesthetics of the supernatural.

Analysis Of Stigmatic Content In State Mental Health Legislative Proposals, David L. Conley

Theses and Dissertations

Despite the proven effectiveness of mental health interventions, services remain limited across the country. Social workers have repeatedly advocated for increased funding, but mental healthcare gaps persist. Disparities could be addressed through the policy process, but critical proposals often do not pass. One of the biggest barriers is the concept of stigma, which could extend into legislatures and influence mental health-related policy outcomes as a form of structural stigma. Factors that influence legislator voting behavior are found in the literature, but studies have not explicitly focused on structural stigma or mental health-specific policy outcomes. Thus, the present study aimed to …

From Abdication To Action: Turning Points In Clinton's Foreign Policy, Eric J. Szandzik

Theses and Dissertations

This research analyzes important turning points in the foreign policy of President Bill Clinton (1993-2000). These turning points include Clinton's decision to not intervene in the Rwandan genocide (1994), and his decision to intervene in Bosnia (1995) and Kosovo (1999). The various reasons why Clinton did, or did not, intervene in those three events are examined. Clinton admitted that not intervening in the Rwandan genocide was the greatest regret of his presidency. The regret of not intervening in Rwanda had a substantial impact on his decision to launch military interventions into Bosnia and Kosovo. The impact of that regret is …

Understanding Droplet Mobility And Penetration In Nonwovens Via Numerical Simulation And Complementary Experiment, Mohammad Jamali 1991

Theses and Dissertations

Water droplet mobility on a hydrophobic surface cannot be guaranteed even when the droplet exhibits a high contact angle with the surface. Droplet mobility is defined as the required force to move a droplet on the surface. In fact, droplet mobility on a surface, especially a fibrous surface, has remained an unsolved empirical problem. As the earth gravity may not be strong enough to initiate water droplet mobility or penetration into some hydrophobic fibrous coatings (electrospun polystyrene), a novel test method was designed. In the experiment, an aqueous ferrofluid droplets rather than water are used so that the body force …

Anti-Tumor Functions Of Sphingosine Kinase 1 And Sphingosine Kinase 2 In Breast Cancer Development, Melissa A. Maczis

Theses and Dissertations

Bioactive sphingolipid metabolite sphingosine-1‐phosphate (S1P) circulating levels have been implicated in breast cancer (BC) progression. BCs usually respond to 17β-Estradiol (E2) through canonical receptor ERα66 for genomic effects, however, E2 also triggers rapid, non-genomic responses. E2 has been shown to activate sphingosine kinase 1 (SphK1), increasing S1P for S1P receptors signaling important for BC. The E2 receptor activating SphK1 has not been identified. We demonstrate triple negative BC cells, expressing only novel ERα splice variant ERα36, E2-induced SphK1 activation for S1P secretion. Tamoxifen, first-line BC endocrine therapy, an ERα66 antagonist but ERα36 agonist, activates SphK1 and increases S1P secretion in …