Digital Commons Network^™

Investigation Of Inosine And Hypoxanthine As Biomarkers Of Cardiac Ischemia In Plasma Of Non-Traumatic Chest Pain Patients And A Rapid Analytical System For Assessment, Don E. Farthing

Theses and Dissertations

Each year in the U.S., approximately 7-8 million patients with non-traumatic chest pain visit hospital emergency departments (ED) for medical evaluation. It is estimated that approximately 2-5% of these patients are experiencing acute cardiac ischemia, but due to the shortcomings of current test methods, they are incorrectly diagnosed and discharged without appropriate treatment provided, thus leading to poor patient outcome and potential medical malpractice litigation.The goals of this research were to evaluate plasma samples for potential biomarker(s) of acute cardiac ischemia prior to heart tissue necrosis, and to ultimately develop a rapid method for detection of the potential biomarker(s) in …

Role Of Vegf-C In Proliferation And Migration In A Cancer Model, Emily Marie Benke

Theses and Dissertations

Head and neck cancer ranks high among the most common cancers world wide. In addition, there is a high recurrence rate, as well as a high prevalence of loco-regional tumor spread. Among many factors contributing to metastasis is vascular endothelial cell growth factor C. VEGF-C is primarily an inducer of new lymph vessel formation, typically during embryogenesis; however, some advanced cancers show a significant increase in VEGF-C expression, suggesting a role in metastasis. In the current study, the effects of VEGF-C expression were tested in HN12 cells, which are highly metastatic and known to express high levels of the chemokine …

Possible Stimulation Of Anti-Tumor Immunity Using Repeated Cold Stress: A Hypothesis, Nikolai A. Shevchuk, Sasa Radoja

Radiation Oncology Publications

Background The phenomenon of hormesis, whereby small amounts of seemingly harmful or stressful agents can be beneficial for the health and lifespan of laboratory animals has been reported in literature. In particular, there is accumulating evidence that daily brief cold stress can increase both numbers and activity of peripheral cytotoxic T lymphocytes and natural killer cells, the major effectors of adaptive and innate tumor immunity, respectively. This type of regimen (for 8 days) has been shown to improve survival of mice infected with intracellular parasite Toxoplasma gondii, which would also be consistent with enhanced cell-mediated immunity.

Presentation of the hypothesis …

Virginia Commonwealth University Undergraduate Bulletin Courses [2007], Virginia Commonwealth University

VCU Bulletins

Listing of undergraduate courses for 2007-2008.

Virginia Commonwealth University Undergraduate Bulletin [2007], Virginia Commonwealth University

VCU Bulletins

Undergraduate bulletin for Virginia Commonwealth University for the academic year 2007-2008. It includes information on academic regulations, degree requirements, course offerings, faculty, academic calendar, and tuition and expenses for undergraduate programs.

Virginia Commonwealth University Graduate And Professional Programs Bulletin Courses [2007], Virginia Commonwealth University

VCU Bulletins

Listing of professional and graduate courses for 2007-2008.

Possible Use Of Repeated Cold Stress For Reducing Fatigue In Chronic Fatigue Syndrome: A Hypothesis, Nikolai A. Shevchuk

Radiation Oncology Publications

Background Physiological fatigue can be defined as a reduction in the force output and/or energy-generating capacity of skeletal muscle after exertion, which may manifest itself as an inability to continue exercise or usual activities at the same intensity. A typical example of a fatigue-related disorder is chronic fatigue syndrome (CFS), a disabling condition of unknown etiology and with uncertain therapeutic options. Recent advances in elucidating pathophysiology of this disorder revealed hypofunction of the hypothalamic-pituitary-adrenal axis and that fatigue in CFS patients appears to be associated with reduced motor neurotransmission in the central nervous system (CNS) and to a smaller extent …

Virginia Commonwealth University Bulletin All Courses [2006], Virginia Commonwealth University

VCU Bulletins

Listing of undergraduate, professional, and graduate courses for 2006-2007.

Jimmy Hit His First Home Run, Eileen N. Rafferty

Theses and Dissertations

This document begins with the end of a life and ends with the beginning of hope. It is a brief description of the artist's history, artistic and literary influences, and subsequent works produced during graduate school, specifically Dichotomy, Swan Dive, and Jimmy Hit His First Home Run. Topics discussed include Human Physiology, Transference, Buddhism, and Bubbles. This document was created in Microsoft Word 2004 for Mac, Version 11.2.

Small Molecules Binding To Serpins, Junaid Afridi

Theses and Dissertations

Serpins are a unique breed of proteins due to their enzymatic mechanism. Two systems were closely monitored during fluorescent binding studies, the ACT-CHY along with the AT:TRY interaction. Four different conformational variants of each system were studied including the native, cleaved, latent and complex forms. Three different fluorescent dyes were used to identify the conformations including ANS, TNS, and bis-ANS. SI studies and protease assays utilizing both Suc-AAPF-pNA and L-BAPNA were instrumental in determining conformations along with gel electrophoresis studies. The hydrophobic dyes bound to the different serpins with varying KD and ΔFmax due to structural variations among the conformers …

Virginia Commonwealth University Bulletin All Courses [2005], Virginia Commonwealth University

VCU Bulletins

Listing of undergraduate, professional, and graduate courses for 2005-2006

Method Of Infant Feeding As A Predictor Of Maternal Responsiveness, Emily Eiwen Drake

Theses and Dissertations

Infants need to develop effective, secure attachment to their primary caregivers in the first year of life. Researchers have not been able to identify all the factors that may influence the development of infant attachment. Most of the studies in this area have been done without regard to infant feeding as a potential factor. Maternal responsiveness appears to be key in the child's development of secure attachment behaviors, yet even after decades of research on infant attachment and maternal responsiveness, there is little evidence available to assist with early identification of families at risk and few interventions known to be …

Virginia Commonwealth University Graduate And Professional Programs Bulletin Appendix A-Graduate And Professional Courses [2004], Virginia Commonwealth University

VCU Bulletins

Supplemental listing of graduate and professional courses for 2004-2005.

Preservice Teacher Education: Alive And Well At Two-Year Colleges, R. Collins, V. Bergeron

Journal of Mathematics and Science: Collaborative Explorations

No abstract provided.

Reviews: Vera L. Zolberg’S Constructing A Sociology Of The Arts, Jeffrey Leptak

Journal of Social Theory in Art Education

Book review for Constructing a Sociology of the Arts, Vera L. Zolberg, Cambridge University Press, New York, 1990.

Reviews: John Lang’S Creating Architectural Theory, Joanne K. Guilfoil

Journal of Social Theory in Art Education

Book review for Creating Architectural Theory, Jon Lang, van Nostrand Reinhold, New York, 1987.

The Merging Of Traditional Chinese Medicine And Western Medicine In China: Old Ideas Cross-Culturally Communicated Through New Perspectives, James A. Schnell

Explorations in Ethnic Studies

The People's Republic of China is engaged in reforms which involve development of its economic, cultural, educational, and political processes. The need for reform has been realized as China has fallen behind the development of the western world in many areas. China closed its doors to the outside world in 1949, and it experienced limited interaction with the outside world until reform began in 1979.

Synthesis Of 3-(Substituted-Aryl)-1,2,3,4-Oxatriazolium-5-Olates As Potential Hypotensive Agents, Mary Quinn Lund

Theses and Dissertations

Hypertension or high blood pressure is a major cause of illness and death in the United States today.^1,2 An estimated thirty-six million people suffer from this disease.³ Prolonged hypertension and its attendant strain on various organs may cause heart failure, brain stroke or kidney damage.⁴ Usually, a pressure of 140/90 mm Hg is taken to be the dividing line between normotension and hypertension.^5,6

The hypertensive condition is generally characterized as either primary (essential) hypertension or secondary hypertension.¹ A specific cause can be identified in secondary hypertensive patients, such as, pheochromocytoma or adrenal tumor. These causes …

Abstracts Of Papers Presented At The 6th Annual Conference On Ethnic And Minority Studies

Explorations in Ethnic Studies

Before developing programs to help minority women, program developers should assess themselves. White men usually create problems that cause minority women to need programs developed. White men who have had minimal social contact with minority women are not qualified to solve minority women's problems. White men ask white women and minority men to give assistance in solving minority women's problems. White women, who have been considered superior to minority women because of social, educational, or economical circumstances, are not qualified to solve minority women's problems. Minority men who have chauvinist values and do not have minority women's concerns at heart …

Virginia Commonwealth University School Of Arts And Sciences Graduate Bulletin [1976], Virginia Commonwealth University

VCU Bulletins

School of Arts and Sciences Graduate bulletin for Virginia Commonwealth University includes information on academic regulations, degree requirements, course offerings, faculty, academic calendar, and tuition and expenses for graduate programs.

Virginia Commonwealth University School Of The Arts Graduate Bulletin [1974], Virginia Commonwealth University

VCU Bulletins

School of the Arts Graduate bulletin for Virginia Commonwealth University includes information on academic regulations, degree requirements, course offerings, faculty, academic calendar, and tuition and expenses for graduate programs.

Unique Characteristics And Implications Of Individual Health Profiles, George Z. Williams

MCV/Q, Medical College of Virginia Quarterly

During the era of the prescientific medicine, people were divided into two categories: those who were sick and those who were not sick. Physicians found it necessary to establish criteria to differentiate the ill and separate them according to symptoms and signs characteristic of classifiable diseases. Because of preoccupation with disease, the concept of the "normal" versus the pathological, as two opposite and definable conditions, was inevitable in the absence of scientific knowledge of human chemistry and physiology. This concept has carried over into the present era of scientific medicine.

Abstracts Of Theses For Graduate Degrees

MCV/Q, Medical College of Virginia Quarterly

Abstracts of graduate degree theses, Medical College of Virginia, June 1970. Summary includes: Radioimmunoassay of HGH and ACTH in Surgically Stressed Patients by James Carrington Rose; Tongue Rolling and Tongue Folding in an American Caucasian Population by Martha Jane Ruebush; Study of the Toxic, Pyrogenic, and Cytopathogenic Properties of Lipopolysacchardie of Salmonella Abortus Equi by Brenda Lee Wright; Influence of the Cutaneous Application of Ice on Isolation and Control of Single Motor Units in Humans by Martha Anne Clendenin; Sodium Dodecyl Sulfate Inactivation of Bovine Liver Glutamate Dehydrogenase by Stanley Clark Yusko; A Study to Determine why a Group of …

Iatrogenic Disorders, Robert H. Moser

MCV/Q, Medical College of Virginia Quarterly

The contemporary physician and his patient are riding the crest of the most dramatic expansion of medical capability in history. But the rapid proliferation of medical knowledge has not been entirely benign. Although our reverses have been minor in contrast to our advances, negative effects cannot be ignored. My discussion involves one aspect of this problem--the emergence of what I have called "Diseases of Medical Progress" (Moser, 1964).

Panel On Arteriosclerosis, William Dock

MCV/Q, Medical College of Virginia Quarterly

Panel on Arteriosclerosis held during the Thirty-Sixth annual McGuire Symposium on Hypertension and Arteriosclerosis, Medical College of Virginia, October 7-9, 1964, moderated by William Dock.

The Proscript (1942-10-22)

Proscript, 1940-1969

Published by the students of the Richmond Professional Institute, College of William and Mary (1940-1947); The Richmond Professional Institute and Virginia Polytechnic Institute cooperating (1947-1955); Richmond Professional Institute of the Colege of William and Mary <1955-1962>; Richmond Professional Institute, Sept. 21, 1962-May 24, 1968; Virginia Commonwealth University, Sept. 20, 1968-May 23, 1969.