Digital Commons Network^™

A Mixed Methods Study: High School Teachers’ Perspectives On Incorporating Mindful Artmaking In Their Classroom As A Mental Health Resource, Sherry A. Bosarge

Theses and Dissertations

Mental health concerns and the need for mental health resources for high school students continue to rise in Virginia. Some of the reported benefits to the current mental health services and resources offered in Virginia schools are increased academic outcomes, attendance, and positive behaviors. The reported barriers to current mental health services and resources are lack of participation, lack of training, time constraints, funding, and resources. This explanatory sequential mixed methods study examined high school teachers’ perspectives on the benefits and barriers to incorporating mindful artmaking in their classrooms as a mental health resource at a local high school. This …

Still An Athlete? An Exploration Of Athlete Identity, Body Appreciation, And Psychological Flourishing In Middle-Aged Former Collegiate Athletes, Kelly Furr

Theses and Dissertations

Collegiate athletes, upon retirement, are encouraged to develop other interests outside of sport to form a well-rounded identity. Yet middle-aged people often struggle to complete recommended strength training and exercise guidelines, and many continue to struggle with body appreciation and psychological well-being beyond adolescence and young adulthood. Using a cross-sectional survey design, 482 former NCAA athletes completed the Athlete Identity Measurement Scale (AIMS), Exercise Identity Scale (EIS), Body-Appreciation Scale (BAS-2), and Flourishing Scale (FS). The study used Structural Equation Modeling (SEM) to determine if athlete or exercise identity positively affects body appreciation and psychological flourishing through the mediating variable of …

A Mixed Method Case Study Of Leadership For Change: Authentic Transformational Leadership In A Local Baptist Church, Hui Sun

Theses and Dissertations

This convergent parallel mixed methods case study explores how a local Baptist church navigated organizational change during and after the COVID-19 pandemic through the lens of authentic and transformational leadership. Grounded in organizational leadership and open systems framework of organizational change, the study examined two primary hypotheses: (1) RBC demonstrated an authentic transformational leadership paradigm in its change processes since 2020, and (2) this paradigm significantly and positively influenced perceived leadership effectiveness.

Qualitative data were collected through semi-structured interviews with six leaders (three pastors, one minister, one staff leader, and one deacon) and 11 raters (five lay leaders, five congregants, …

Knowing By Heart: Philosophical Dimensions Of Humanistic Mathematics Education, Catherine Henney

Theses and Dissertations

This project seeks to revive interest in late twentieth century humanistic mathematics education (HME) so that its principles might cross the boundary of higher education and settle in corners of the K-12 math education space. In particular, HME’s theme of teaching math humanistically directs attention to features and phenomena that bear strongly on students’ daily classroom experiences. Personhood, agency, inquiry, meaning, environment, feelings, relationships: these elements invite a more thorough meditation and philosophical analysis. Though it is a largely philosophical endeavor, this project is enlivened by classroom vignettes and case studies that bring practical relevance to HME’s core principles. Chapters …

Scopolamine-Induced Modulation Of Serotonin And Dopamine Transporters Activity: Behavioral And Molecular Insights Into Rapid Antidepressant Action, Deepak Karunakaran

Theses and Dissertations

Major depressive disorder (MDD) affects over 350 million individuals worldwide and is characterized by profound dysregulation of serotonin (5-HT) and dopamine (DA) systems that govern mood, reward processing, and motivation. The serotonin transporter (SERT) and dopamine transporter (DAT), both dynamically regulated through phosphorylation, serve as critical determinants of synaptic monoamine signaling. Despite decades of therapeutic development, current antidepressants require 4-6 weeks to achieve efficacy, and approximately one-third to half of patients develop treatment-resistant depression. The emergence of rapid-acting antidepressants like ketamine represents a paradigmatic shift, demonstrating symptom relief within hours; however, ketamine's therapeutic potential remains constrained by abuse liability, dissociative …

Therapy-Induced Senescence In Cancer: Developing Senolytic-Based Combination Strategies To Delay Re-Emergence Of Triple-Negative Breast Cancer, Eesha Chakraborty

Theses and Dissertations

Therapy-induce senescence (TIS) represents a major biological outcome of many anticancer treatments and is increasingly recognized as a strategic vulnerability in triple negative breast cancer, which is a highly aggressive subtype with limited therapeutic options and frequent relapse. Here, we probed TIS as a primary cellular response that may ultimately compromise long-term outcomes using standard chemotherapeutic agents in TNBC as well as the antibody-drug conjugate sacituzumab govitecan (SG). Both chemotherapy and SG reliably induced pronounced senescence across TNBC models, yielding durable growth arrest, however, also generating a persistent reservoir of viable tumor cells capable of eventual proliferative recovery, a hallmark …

Effectiveness Of Immersive Virtual Reality Combined With Task-Specific Training On Hemiplegic Arm Function Following Stroke: A Single Case Series Study, Rahsaan J. Holley

Theses and Dissertations

Motor recovery of the arm following a neurological injury is a common goal of the rehabilitation process for individuals impacted by the condition . Due to the long-term functional implications of impaired arm movement, individuals are often trained to use compensatory strategies to complete functional tasks without incorporating the weakened limb. While compensatory strategies offer stroke survivors the opportunity to regain a level of independence, such approaches fail to directly address the underlying causes of the disability (i.e., limited range of motion, decreased strength, poor coordination, motor planning difficulties) which can unfortunately result in long-term impairment and functional disability.

Motor …

Swarming Segregation: Leveraging Swarm Intelligence And Regionalization As Instruments For School District Desegregation, Jeffrey Wooten

Theses and Dissertations

Even after Brown led to the South briefly having the most diverse schools in the nation, schools throughout the Northeast have remained the most segregated in the nation for decades. While federal jurisprudence has made compelling desegregation pursuant to the Equal Protection Clause more challenging, New Jersey has a particularly favorable landscape to address severe segregation. With a highly diverse, densely populated public enrollment, favorable state constitutional precedent, and a history of successfully compelling desegregation, New Jersey is fertile ground exploring regional desegregation. Scholars, judges, and even plaintiffs in ongoing litigation (Latino Action Network v. N.J.) have called for New …

Place, Culture, And Care: A Socioecological Examination Of Type 2 Diabetes Among Hispanics In The U.S., Danielle Montoya

Theses and Dissertations

Introduction: Type 2 diabetes (T2D) disproportionately affects U.S. Hispanic populations. This dissertation examined whether structural determinants fundamentally drive T2D disparities among Hispanics, with attention to within-group racial heterogeneity.

Methods: Three studies utilized nationally representative data. Study 1 examined neighborhood segregation and ethnic enclave residence associations with T2D using restricted NHANES data (2011-2018, n=5,056). Study 2 investigated acculturation and T2D associations using restricted NHANES data (2011-2018, n=4,540). Study 3 analyzed patient-provider racial/ethnic concordance and adequate diabetes care using MEPS data (2008-2021, n=17,138).

Results: Structural factors demonstrated primacy across all studies. Neighborhood segregation (aOR=1.17, p>0.05) and ethnic enclave residence showed no …

Exploring The Role Of Host Immune Responses And Bacterial Sensory Pathways In The Development Of Treponema Denticola-Mediated Periodontal Disease, Annie N. Hinson

Theses and Dissertations

Periodontitis is a chronic inflammatory disease driven by dysbiotic microbial communities and maladaptive host responses. Treponema denticola, a spirochete pathobiont, is strongly associated with disease severity. However, the molecular mechanisms underlying its interaction with host tissues and regulation of virulence remain incompletely understood. This work examines both the epithelial immune responses and bacterial transduction systems that shape T. denticola pathogenesis. Transcriptomic analysis of gingival keratinocytes revealed IL-36γ as the most highly induced cytokine following infection with T. denticola. Functional studies demonstrated that IL-36γ induction occurs in a dose- and time-dependent manner through TLR2/6 signaling, requiring the NF-κB, PI3K/Akt, and …

Relationship Extraction Using Retrieval Augmented Generation For Biomedical Dataset, Jannat .

Theses and Dissertations

With the increasing number of structured and unstructured data, obtaining reliable information effectively has become crucial. In the biomedical domain, extracting information from the scientific papers is crucial in order to stay up-to-date with accurate information, given the increased pace by which new research studies are published. This work focuses on identifying relationships between entities that are extracted from the abstracts and titles of biomedical research papers. In this work, we developed a Retrieval Augmented Generation (RAG) based system to automatically identify relations between biomedical entities. We evaluate multiple open source Large Language Models (LLMs) and the number of examples …

Characterization Of Outer Surface Protein C Of Borreliella Role In Host Tropism, Kathryn Mf Chambers

Theses and Dissertations

The Lyme disease spirochetes, Borreliella spp., are maintained in nature through a complex enzootic cycle involving Ixodes ticks and a diverse set of reservoir hosts. The outer surface protein C (OspC) of the bacterium is an essential virulence factor required for transmission from ticks and early infection of mammals. Deletion of ospC abolishes infectivity, yet the precise molecular mechanisms underlying OspC function remain incompletely defined. In this dissertation, I examined the contribution of OspC type identity to host specificity. OspC is highly diverse, with over 30 genetically stable types described. While intra-type sequences are conserved (>95% amino acid …

Genetic Studies At The Intersection Of Alcohol Use And Pain, Walker Rogers

Theses and Dissertations

Alcohol use disorder and pain are complex public health concerns affecting millions of people, and these conditions are often characterized by a bidirectional relationship. People experiencing pain may drink alcohol for its analgesic effects. In turn, excessive consumption of alcohol can lead to conditions that cause pain, leading to an escalating feedback loop of pain and alcohol use. Negating this cycle requires a nuanced understanding of the mechanisms underlying alcohol analgesia, which are presently not fully understood. The Miles and Damaj labs have previously shown that ethanol-induced antinociception is moderately heritable in mice, indicating a genetic component to the trait. …

The Design Of A House, Lars Mattingly

Theses and Dissertations

Photography lends itself to both damaging and facilitating connection, the camera at once a weapon of destruction and a catalyst for change. The Design of a House is a call to love deeply. In the aftermath of body trauma, I use portrait photography to reconnect with myself and others. Through making portraits, I bridge my own gap between fear and intimacy. Primarily working with film-based cameras and hand-sensitized photographic materials, I reintroduce touch through process. The slowness, delicacy, and tactility of these acts offer a safety I am learning to trust. When photographing myself, my mother, and my partner, I …

Opioid Tolerance And Withdrawal In The Mouse Colon, James Fune

Theses and Dissertations

Constipation is a major clinical obstacle associated with opioids, prompting patients to discontinue treatment due to pain, discomfort, and psychosocial stressors. Moreover, chronic users become tolerant to the analgesic effects of opioids, but not to their constipating effects. Upon cessation of long-term treatment, serious diarrhea–among other somatic signs of withdrawal–may ensue. These symptoms become a driving factor for relapse, causing patients to restart opioid treatment. In this study, we aim to understand mechanisms that contribute to opioid tolerance and withdrawal in the colon. Previous findings suggest that constipation occurs partly due to the colon’s lack of tolerance to opioids’ inhibitory …

Exploring Western Clinicians’ Treatment Of Cultural Concepts Of Distress, Lisa Y. Chung

Theses and Dissertations

As the rates of diverse ethnic populations and therefore cultural concepts of distress continue to grow in the United States, it becomes critical to learn and understand how western-trained mental health professionals are selecting treatments and implementing them. However, there is a paucity of research on cultural concepts of distress as a whole and much less on the psychotherapy of cultural concepts of distress in the United States. This exploratory study aimed to explore the treatment plan of mental health clinicians in the United States when encountering the Korean cultural concept of distress, hwabyung. Ninety-eight clinicians were recruited from Arkansas, …

Exploring The Development Of Students' Calling To The Work Of An Hod Practitioner In An Undergraduate Hod Degree Program, Neil Dana Rahbar-Daniels

Theses and Dissertations

This dissertation project consisted of a multiple case qualitative study to explore indications of cross-influences between students’ experiences of learning takeaways as participants in one or more HOD undergraduate degree courses and accompanying experiences (if any) of perceiving and/or living a calling to work as HOD practitioners. This phenomenological inquiry involved four undergraduate students who had completed one or more HOD degree courses at Mid-Atlantic States University (MSU as a pseudonym) during a two-year period. Each participant attended a single interview of about 90 minutes in duration, responded to a short vocational calling survey as a guide for interview questioning, …

From Trans Health To Vaccines: A Theoretically Driven Model Exploring Factors Related To Susceptibility To Medical Misinformation, Catherine Wall

Theses and Dissertations

Medical misinformation represents a significant threat to both individual and public health. While some consequences of this form of misinformation are relatively benign, there can be serious consequences ranging from a decreased trust in healthcare systems to an increased likelihood of epidemic outbreak and death. One such consequence can be seen in the recent legislative actions taken regarding access to transgender healthcare in the United States. Gender affirming care has been shown to benefit the mental well-being of transgender youth and adults; however, the demonstrably false information that underlies these legislative efforts can and has yielded significant harm. But what …

Beliefs Related To Diagnosing Bpd And Complex Ptsd, Bailey Pascuzzi

Theses and Dissertations

There has been speculation that Borderline personality disorder (BPD) and Complex post-traumatic stress disorder (Complex PTSD) are the same disorder or represent separate disorders on a broader trauma spectrum (Frost et al., 2020; Lewis & Grenyer, 2009). BPD and Complex PTSD share several symptoms but differ in their presentation (Ford & Courtis, 2021). Because the two disorders present so similarly, it could be that clinicians have difficulty differentiating them, leading to misdiagnosis (Miller, 2014). This study examined clinicians’ diagnostic decision-making and stigma toward BPD and Complex PTSD. Participants (N = 426) completed an online survey where they diagnosed a written …

“Some Vague Utopia”: Searching For Urania, Moira L. Neve

Theses and Dissertations

Despite the global pendulum swing of gender trouble marked by the United States’ President’s declaration that there are only two sexes, activists have been rejecting assimilation (ie. defining equality as gay marriage or queer people in the military) within queer studies long before 2025. In the first half of the 20th century, a journal by the name of Urania (1916-1940), privately published and circulated to their home base in the United Kingdom and beyond, five editors (Esther Roper, Eva Gore-Booth, Jessey Wade, Dorothy Cornish, and Irene Clyde/Thomas Baty), challenged the gender binary and the resulting assumptions of heterosexual marriage. This …

The General Movement Optimality Score-Revised (Gmos-R): An Early Biomarker For Developmental Delays, Shaaron E. Brown

Theses and Dissertations

The General Movement optimality score may provide insight into the relationship of term age General Movements and future neurodevelopmental disabilities and could be an early biomarker. This dissertation aimed to determine the relationship between term age neurologic function, measured by the optimality score of the General Movements, and postural control at term and three months (Chapter 2), and the relationship between neurologic function, at term and three months, and 12 month cognitive and motor outcomes (Chapter 3) and the impact of intervention on neurologic function and postural control at three months and on 12 month cognitive and motor outcomes in …

Exploring Prenatal Cannabis Use Among Young Pregnant Bisexual Individuals: A Mixed Methods Study, Nicole Boss

Theses and Dissertations

The perinatal period is a critical time for health behaviors with outcomes that have short- and long-term effects for both childbearing person and child. Research indicates that young bisexual people are at greater risk of unintended pregnancy, experience psychosocial health disparities, and may be more likely to use cannabis during pregnancy. Few studies have examined this phenomenon. This study is a secondary analysis of mixed methods data from a longitudinal cohort study. Thematic analysis of qualitative data (n=12) revealed the contextual adaptivity of cannabis use, with participants explaining the situations and rationales which motivated their cannabis use changed over time. …

Establishing A Conventional Linac-Based Electron Flash Beam, Justin Defrancisco

Theses and Dissertations

Problems: A rediscovered radiotherapy technique, FLASH, involves increasing the dose rate to >40 Gy/s. For a given dose, FLASH is shown to decrease the normal tissue complication probability without affecting the tumor control probability. More preclinical studies are necessary to confirm and enable these desirable properties on humans. Current preclinical investigations have diverse constraints, requiring FLASH apparatuses with flexible parameters and accurate control. However, there are limited FLASH platforms available, the existing ones are costly. Our institution is not in possession of any such infrastructure. Even if available, dosimetry and beam control in FLASH are extremely lacking. There is …

Social Support, Tobacco Attitudes/Perceptions Of Harm, And Asthma Status As Moderators In The Association Between Tobacco Exposure And Cotinine Levels, Rachel L. Pitts

Theses and Dissertations

Tobacco use and exposure are linked to adverse health outcomes (e.g., respiratory conditions) and increased healthcare utilization (e.g., emergency room visits). This study examined the moderating role of social support, tobacco attitudes/perceptions of harm, and asthma status on associations between tobacco use (e.g., combustible product use) and exposure (e.g., secondhand smoke) and cotinine levels among individuals in Richmond, Virginia. We also explored differences in tobacco-related variables by asthma status and associations among tobacco use, secondhand smoke exposure, cotinine levels, and asthma control. Youth (n = 201) and adults (n = 209) (95.7% Black/African American; 60.6% female; 65.8% non-tobacco users; 21% …

Molecular Mechanisms Of Kynurenine-Mediated Lifespan Regulation In Yeast, Ryan E. Counterman Jobb

Theses and Dissertations

The kynurenine pathway is a highly conserved pathway that acts as the primary pathway for tryptophan catabolism and has been found to be involved in lifespan regulation across many diverse organisms. Caloric restriction (CR) is the only known dietary intervention to date that both increases the mean lifespan and the health span of multiple organisms, although the molecular mechanisms of these effects are not fully understood. There are known and sometimes contradictory relationships between the kynurenine pathway activity and the life- extending effect of CR but the crosstalk between the two is not well characterized. Understanding these relationships could lead …

Sarge, Jon F. Merrill

Mighty Pen Project Anthology & Archive

A short story on how a service dog can change a man's life.

Articles, stories, and other compositions in this archive were written by participants in the Mighty Pen Project. The program, developed by author David L. Robbins, and in partnership with Virginia Commonwealth University and the Virginia War Memorial in Richmond, Virginia, offers veterans and their family members a customized twelve-week writing class, free of charge. The program encourages, supports, and assists participants in sharing their stories and experiences of military experience so both writer and audience may benefit.

Tunnel Rat - Part 2, Gene Pearson

Mighty Pen Project Anthology & Archive

Our combat medic has a much needed conversation with the tunnel rat on whether intervention is needed; an understanding is reached.

Articles, stories, and other compositions in this archive were written by participants in the Mighty Pen Project. The program, developed by author David L. Robbins, and in partnership with Virginia Commonwealth University and the Virginia War Memorial in Richmond, Virginia, offers veterans and their family members a customized twelve-week writing class, free of charge. The program encourages, supports, and assists participants in sharing their stories and experiences of military experience so both writer and audience may benefit.

God Of Baghdad, Phillip Trezza

Mighty Pen Project Anthology & Archive

In a powerful one-act play, a young Army medic rushes to a crowded Baghdad street corner destroyed by an IED hidden in a truck. The human carnage is everywhere; he must choose who will live and who will die. In those moments, in that place, he must be the God of Baghdad.

Articles, stories, and other compositions in this archive were written by participants in the Mighty Pen Project. The program, developed by author David L. Robbins, and in partnership with Virginia Commonwealth University and the Virginia War Memorial in Richmond, Virginia, offers veterans and their family members a customized …

Exploring The Educational Gap Of Virginia English Language Learners: Challenges And Opportunities For Academic Success, Amanda Purcell, Sochitl Rodriguez Kauffman

UROP Posters

English Language Learners (ELLs) in the state of Virginia have significantly lower scores in the Standards of Learning (SOL) assessment exam than those of their English-speaking peers. The SOL measures students’ mastery of knowledge and skills taught in the classroom, and over the last decade, passing rates of the assessment’s core subjects amongst ELLs have continued to decrease and remain relatively low. In the 2023-2024 academic year, the average passing rate for ELLs who took the Writing SOL was only 26%, with Science being not much higher at 29%, and Reading at 33%. For the non-ELL student body, average rates …

Ocean Acidification Mitigation: Potential Expansion Of Sav Restoration Strategy In The Chesapeake Bay, Cree N. Taylor

UROP Posters

Zostera marina is a species of marine macrophyte that has been largely prioritized in past submerged aquatic vegetation (SAV) restoration initiatives within the Chesapeake Bay because of its 1) previous abundance, 2) demonstrated carbon burial abilities, and 3) observed ability for meadows of Z. marina to ameliorate low pH conditions. Due to the temperature variability and poor water quality associated with anthropogenic disturbances in the Chesapeake Bay, Z. Marina beds have experienced several die-off events with limited capacity for regrowth. This systematic review explored the possible benefits of focusing future SAV recovery initiatives on ensuring a diverse variety of SAV …