Digital Commons Network^™

The Walls We Put Up - Loneliness And Belonging In Urban Co-Living, Richard Rozewski

Theses and Dissertations

ABSTRACT

Concurrent issues of social isolation and loneliness have long been recognized as problems that affect seniors but it is also being proven to affect young people as well, specifically with the rise of new technologies and a perception of connectedness. Co-living provides one alternative design solution to traditional housing models which can unlock a range of social benefits.

MOTIVATION

Loneliness is an unfortunate reality of modern life and it is something that most people experience at least once in their life (Cacioppo & Patrick, 2008). A study carried out by Berguno, Leroux McAinsh, Shaikh (2004), showed that 80% of …

Geospatial Analysis Of Invasive Plant Species And Their Threats To Ecological Functionality At The Vcu Rice Rivers Center, Erik W. Kellogg

Theses and Dissertations

Invasive plants are a significant threat to native ecosystems and to biodiversity. They are often strong competitors and have multiple techniques to outcompete native plants. Thus, controlling or removing invasive plants facilitates the restoration of native ecosystems. We used GPS technology coupled with field surveying techniques adapted from the U.S. Fish and Wildlife Service to locate and identify invasive plants present within VCU’s Rice Rivers Center. We digitally overlaid a 50-meter x 50-meter grid system over the property. In each grid cell we recorded visual estimations of invasive plant coverage sorted into modified Daubenmire cover classes and used ArcGIS for …

Associations Between Ethnic-Racial Identity, Family Factors And Alcohol Problems Among Diverse Emerging Adults, Chloe Walker

Theses and Dissertations

The current study examined how multiple dimensions of ethnic-racial identity (ERI) were associated with alcohol use and alcohol use disorder (AUD) symptoms and how these relations varied by individuals’ ethnic-racial group among 1850 diverse emerging adults (M = 18.46, SD = .38). Further, measurement invariance of the Ethnic Identity Scale-Brief (EIS-B) was tested across Latinx, White, Black, Asian, and Multiracial students. Additionally, alternative models were examined that tested whether family factors (i.e., parent education and family history of alcohol problems) moderated the relations between ERI and alcohol problems to further examine nuances in these relations. Results indicated that the …

Examining How Primary Care Team Structures Are Used And Their Effect On Cross-Disciplinary Relationships: A Qualitative Study, Matthew J. Depuccio

Theses and Dissertations

Team-based primary care is an innovative care delivery model that has the potential to improve access to comprehensive, coordinated, and high-quality patient care. It is understood that in order for primary care teams to work effectively, health care providers must work across disciplinary boundaries and develop strong relationships that enable them to coordinate their roles and expertise. This research investigated how health care providers make use of different team structures (i.e., tools) to manage their interdependent work, enabling them to deliver team-based primary care. This research also examined how team structures influence the intra-team relationships important for coordinating care. By …

Cellular Mechanisms By Which Alcohol Promotes Hiv Protease Inhibitor-Induced Hepatotoxicity, Michael Hinton

Theses and Dissertations

CELLULAR MECHANISMS BY WHICH ALCOHOL PROMOTES HIV PROTEASE INHIBITOR-INDUCED HEPATOTOXICITY

Michael Hinton, B.S.

A dissertation submitted in partial fulfillment of the requirements for the degree of Doctor of Philosophy at Virginia Commonwealth University

Virginia Commonwealth University, 2019

Major Director: Huiping Zhou

Professor, Department of Microbiology and Immunology

The development of highly-active-antiretroviral therapy(HAART) has allowed management of HIV and extended the lives of those infected. Alcohol abuse, which is very common in HIV-1 infected patients, is one of the most important co-morbid risk factors for liver injury and has been associated with the occurrence of serious metabolic syndrome and subsequent discontinuation …

Examination Of Strain-Dependent Differences In S. Sanguinis Virulence And Growth, Shannon Baker

Theses and Dissertations

Streptococcus sanguinis, an abundant and benign inhabitant of the oral cavity, is an important etiologic agent of infective endocarditis, particularly in people with pre-disposing cardiac valvular damage. Although commonly isolated from patients with IE, little is known about the factors that make any particular S. sanguinis isolate more virulent than another or, indeed, whether significant differences in virulence exist among isolates. To investigate the virulence of multiple isolates, a variation of the Bar-seq (barcode sequencing) method was employed. A conserved chromosomal site was identified for subsequent insertion of a barcode identifier, unique for each strain. Barcode insertion did not …

Enhanced Proteomics Resolves Kcc2 As A Novel Therapeutic Target For Traumatic Brain Injury, Pavel N. Lizhnyak

Theses and Dissertations

The development of traumatic brain injury (TBI) therapeutics and effective translation to clinic remains stubbornly elusive despite the high prevalence of TBI within the United States and across the globe. Interventions must be devised around testable targets, appropriately timed to intercede on secondary results. Here, we have utilized temporal neuroproteomics as an ideal approach to inform on the complex biochemical processing in order to address the well-recognized temporal evolution of TBI pathobiology and interrogate a novel therapeutic target in a mild-moderate rat Controlled Cortical Impact (CCI) within perilesioned somatosensory cortex. First, our findings revealed 2047 proteins significantly impacted within the …

Loneliness And Sleep Disturbance In Older Americans, Sarah C. Griffin

Theses and Dissertations

Loneliness is a risk factor for premature mortality but the mechanics of this relationship remain obscure. A potential mechanism is sleep disturbance. The present study aimed to examine the association between loneliness and sleep disturbance, evaluate loneliness as a risk factor for sleep disturbance and vice-versa, model effects between loneliness and sleep disturbance over time, and evaluate a mediation model of loneliness, sleep disturbance, and health. Data came from the 2006-2012 waves of the Health and Retirement Study, a nationally-representative study of older Americans; participants > 65 were included (n=11,400). Analyses included (i) linear regressions accounting for complex sampling and (ii) …

The Role Of Syndecan-1 And Extracellular Vesicles In Breast Cancer Brain Metastasis, Megan R. Sayyad

Theses and Dissertations

Breast cancer metastasizes to the brain in 15-30% of all breast cancer cases, and metastasis is the predominant cause of breast cancer-related deaths. Patients with HER2-enriched and triple-negative breast cancers (TNBCs) are more likely to develop brain metastases. While targeted therapies exist for HER2-enriched breast cancers, there are no effective treatments for TNBCs. Thus, a greater understanding of how these cancers spread to the brain is critical. In order to spread to the brain, disseminated breast cancer cells must overcome 2 major steps—crossing the blood-brain barrier (BBB) and survival and successful colonization of the distinctive and mostly cellular brain environment. …

Indirect Relatedness, Evaluation, And Visualization For Literature Based Discovery, Sam Henry

Theses and Dissertations

The exponential growth of scientific literature is creating an increased need for systems to process and assimilate knowledge contained within text. Literature Based Discovery (LBD) is a well established field that seeks to synthesize new knowledge from existing literature, but it has remained primarily in the theoretical realm rather than in real-world application. This lack of real-world adoption is due in part to the difficulty of LBD, but also due to several solvable problems present in LBD today. Of these problems, the ones in most critical need of improvement are: (1) the over-generation of knowledge by LBD systems, (2) a …

Arab Americanesque, Hannah W. Shaban

Theses and Dissertations

Culture, as defined by Edward Said, is a concept of identity selectively curated through imperialism. Through my ceramic practice, I explore what constitutes my cultural identity as a first generation Arab American. My work, primarily influenced by family narrative was initially expressed through investigations in the figure and viewer relationships with my sculpted figures. As my research progressed into Western Imperialism, I began noticing extensive evidence of colonialism’s lasting effects, especially within Western consumer markets. Interest in the writings of Said, works by French Orientalist painters, family memory, and a general displeasure with the plethora of Middle Eastern design used …

Scott's Addition Green Space Plan: Small Changes Making A Big Impact, Sara J. Rozmus

Master of Urban and Regional Planning Capstone Projects

Scott’s Addition is a fast growing, postindustrial neighborhood situated on the north side of West Broad street and bordering Henrico county to the west. The current building stock in Scott’s Addition consists of industrial and manufacturing buildings, and warehouses, much of which have been converted into multi-family residential buildings, commercial businesses, office and restaurant space (Neighborhood History, 2018). As a consequence of its original land use and zoning most of Scott’s Addition is dominated by concrete surface area and sprawling, one to two story building structures. Adaptive reuse of existing buildings has brought new investment and residents into the neighborhood …

Vcu Campus Tree Plan, Bilal Damaj

Master of Urban and Regional Planning Capstone Projects

Throughout the past several years VCU has grown tremendously as a large public research university and an anchor institution within the city of Richmond However, VCU also has been working towards a more sustainable future and is committed to furthering sustainability in its community and campuses. While VCU has several long-range plans dedicated towards different aspects of the University’s planning and design initiatives, the University does not have any plan dedicated specifically towards its campus trees or tree canopy. An analysis of the existing conditions on VCU’s campuses found that there is low amount of urban tree canopy cover, high …

Planning An Inclusive Entrepreneurial Ecosystem In Norfolk Virginia, Matthew A. Cline

Master of Urban and Regional Planning Capstone Projects

Provides an overview of Norfolk’s emerging entrepreneurial ecosystem and challenges associated with its disadvantaged entrepreneurs. Presents policy recommendations in creating more equitable environment for these small business ventures.

Making A House A Home: A Community Plan For Regional Engagement On Housing, Anna N. Clemens

Master of Urban and Regional Planning Capstone Projects

This plan was developed for Virginia Organizing, a statewide non-partisan grassroots organization dedicated to challenging injustice by empowering local communities. The plan was designed to produce a replicable model for organizers embarking on housing campaigns. Research on the Virginia Organizing chapters in Fredericksburg and Charlottesville was completed as well as on the broader affordable housing ecosystems in these regions. This research was gathered through interviews with regional and local planners, organizers, non-profit representatives, and individuals working in the intersection of planning and organizing. Chapter member research, which guided this plan, was conducted through surveying, focus groups, and qualitative mapping. Findings …

A Strategy For The Cultivation Of Community Strength, Jessica Tomasita Turner

Master of Urban and Regional Planning Capstone Projects

This professional plan is a community-based template for neighborhoods in the urban landscape that were once thriving and are now struggling with population stability. The study area is found in the south side of Richmond, Virginia in the neighborhoods of Bellemeade and Oak Grove. The recommendations of this plan are focused on the cultivation of long-term residents. The research of this plan investigates three elements that can be focused on in order to cultivate this demographic: aging in place, abandonment due to family growth, and housing issues. These three elements have been researched and developed in order to craft well …

Ampthill Neighborhood Market Analysis & Community Strengthening Plan, Claude P. Armstrong

Master of Urban and Regional Planning Capstone Projects

This is a Strengthening Plan in support of a future commercial corridor development in the Ampthill Neighborhood of Chesterfield County. It is a part of a larger strategy along Jefferson Davis Highway to strengthen ties between neighborhoods and businesses. The Plan encourages economic and community development to create a welcoming destination. A foundation for economic development results and a community road map to assist in navigating discussions, leveraging assets and upgrading transportation infrastructure. This traditionally working-class neighborhood south of Richmond has experienced major demographic change. For others to venture into the area and “get to know it”, Ampthill may …

Guiding Growth: A Growth Management Plan For Powhatan County, Julia E. Hensley

Master of Urban and Regional Planning Capstone Projects

This plan offers Powhatan County a series of analyses and recommendations to maintain their rural character. Because of its proximity to the City of Richmond and other more-populated localities, Powhatan has been experiencing accelerated growth recently compared to historically. This document analyzes past development trends, current development trends, and projects future development trends and density scenarios. It pays close attention to the county’s predetermined Special Areas as locales for growth. Following the analyses, there were numerous obvious suggestions to be made to the county’s current growth management tools that could help them strengthen their ability to maintain and preserve their …

Impact Investment Strategy: Linking Health & Housing, Elizabeth G. Mckinsey

Master of Urban and Regional Planning Capstone Projects

The purpose of this plan is to create an impact investment strategy for RMHF that explicitly links health and housing. The strategy will use impact investing, an investment strategy that directs capital to enterprises that generate social and or environmental benefits for the surrounding community. One of RMHF’s goals is for the investment strategy to offer strategies that address the entrenched racism and inequities in the City of Richmond. Impact investing will enable RMHF to be a contributing partner with Richmond as it moves away from a history of unfair housing policies that negatively impact countless citizens to a healthier, …

Residential Fire Impacts On Richmond, Virginia: A Plan For Identifying And Educating Our Most Vulnerable Communities, Jennifer L. Tillett

Master of Urban and Regional Planning Capstone Projects

In 2017, 1.3 million fires in the U.S. caused 3,400 deaths, 14,600 injuries, and $23 billion in loss. Vulnerable populations are less resilient due to their lack of adequate access to financial, medical, and community resources as well as their propensity to reside in substandard housing. This plan studies the impacts of Richmond’s residential fires (2015-2017) on vulnerable communities within the city. Its purpose is to provide an understanding of where fires occurred in vulnerable communities and to recommend actions for prevention education.

The plan is divided into six sections: Introduction, Background, Methodology, Findings, Recommendations, and Implementation. A Social Vulnerability …

Metaproteomic Investigation Of The Vaginal Microbiome In Pregnancy, Zaneera Hassan

Theses and Dissertations

The development of early diagnostics and prevention strategies for preterm birth is an important global health challenge with the potential to impact over 15 million children annually, by improving health outcomes and reducing economic burden. Advances in microbial sequencing technology have opened the door to 16S rRNA gene survey, whole metagenomics, and whole transcriptomics, providing molecular evidence that the composition of the vaginal microbiome affects pregnancy outcomes in women, particularly those of African descent. A current gap in our molecular level understanding of the vaginal microbiome as it relates to healthy pregnancies is the metaproteome which comprises proteins from both …

Associations Between Expressed Emotion, Mental Health, And Functioning In Families: Child Asthma Status As A Moderator, Katherine W. Dempster

Theses and Dissertations

Expressed emotion (EE), the affective attitudes and behaviors of one toward another, can affect caregivers’ behaviors toward their child. Research examining associations between EE and child/family outcomes is mixed; these associations may be affected by other influences such as the presence of a chronic disease or parent mental health. In this study of families living in an urban area, we examined associations between EE and child outcomes (anxiety/depressive symptoms) and family functioning, with parent anxiety as a covariate. We evaluated child asthma status as a moderator as the presence of a chronic illness may strengthen the association between EE and …

What's In A Message? The Impact Of Patient-Clinician Email Message Content On Patient Health Outcomes And Healthcare Utilization, Dawn M. Heisey-Grove

Theses and Dissertations

Introduction

In the upcoming chapters, we present our study findings as three papers ready for submission to peer-reviewed journals. The first paper describes the associations between taxa and the characteristics of the patients and clinic staff who exchange those messages. The second paper explores the associations between those taxa and patients’ healthcare utilization. The third paper presents associations between taxa and patient health outcomes for diabetes and hypertension. We conclude with how the three papers are related and highlight the importance of this research.

Across the three papers, we reference a theory-based taxonomy we developed specifically for secure messaging. A …

In Memoriam

Art Inquiries

In Memoriam: Charles (Randy) Mack, long-time SECAC member and past president of the organization, died in Columbia, SC on October 31, 2018. He was 78. Here, four SECAC members offer memories of Randy, to whom this issue of Art Inquiries is fondly dedicated.

Art Inquiries, Xvii:4, Full Issue

Art Inquiries

No abstract provided.

The Impact Of Social Determinants Of Health On The Efficacy Of School-Based Interventions For Adolescents With Adhd, Cathrin D. Green

Theses and Dissertations

Adolescents with Attention-deficit/hyperactivity disorder (ADHD) often experience impairment in academic functioning in the school and home environment. Because of this, many school- and clinic-based interventions have been developed to target these problems. Initially, clinic-based interventions were mainly used; however, these interventions were associated with many barriers to care, such as lack of transportation, financial resources, and time. Therefore, school-based interventions were developed to address these barriers. However, there has been minimal research evaluating the role of social determinants of health on the efficacy of school-based interventions. In a sample of 222 adolescents with ADHD randomly assigned to receive either a …

Impact On Bacterial Micro-Leakage In Exposed Root Canal Obturation Material In Teeth Irrigated With Different Solutions, Khalifa W. Alhaddad

Theses and Dissertations

Purpose: Determine the timeframe of bacterial penetration that occurs to the apex when obturation material (gutta percha) is exposed to bacteria for a set period of time (45 days) and to determine if bacterial penetration of the obturated root is influenced by the type of irrigant used during the final rinse (17% EDTA vs 2% Chlorhexidine vs full strength 5.25% NaOCl). Methods: Thirty-six extracted teeth, including six controls, were instrumented and irrigated with 5.25% NaOCl followed by a final rinse of either: 17% EDTA, 2% Chlorhexidine, or 5.25% NaOCl, and then obturated. Each root was suspended between two chambers: the …

Optically Transparent Antennas And Filters For Smart City Communication, Ryan B. Green

Theses and Dissertations

Incremental usage of mobile devices demand a new generation of wireless networks (5G) to provide faster data rates, more reliable coverage, monitor city infrastructure usage, and increase network capacity. The frequencies proposed for the upcoming 5G network would result in shorter broadcast distances and network dead zones, countered by incorporating transparent antennas into glass high rises. Transparent antennas possess, however a major challenge: low gain. This lower gain can be countered by means of employing antennas in an antenna array, boosting the gain and even giving the array the ability to beam form for the upcoming 5G network. The 5G …

Comparison Of Patient Factors Influencing The Selection Of An Orthodontist, General Dentist, Or Direct-To-Consumer Aligners For Orthodontic Treatment, Jeffrey C. Olson

Theses and Dissertations

Purpose: To evaluate the factors that influence potential orthodontic patients choosing between an orthodontist, general dentist, and direct-to-consumer (DTC) aligners for their treatment, and to determine the demand for each provider type.

Methods: An electronic survey was administered to 250 individuals among the general population of adults in the United States. Questions were designed to determine the respondent’s level of interest in pursuing orthodontic treatment with each provider type, evaluate their current level of knowledge concerning provider options, and identify factors influencing their selection. Pearson’s chi-squared test and ANOVA were used to evaluate the factors influencing patients in …

Evaluation And Comparison Of Periapical Healing Using Periapical Films And Cone Beam Computed Tomography: Post-Treatment Follow Up, Adam S. Polinsky

Theses and Dissertations

Purpose: The purpose of this study was to assess the radiographic changes in periapical status and analysis of healing determined using periapical radiographs (PA) versus cone beam computed tomography (CBCT) pre-operatively and at 3-64 months following endodontic treatment.

Methods: Pre/post treatment radiograph and CBCT scans of patients who had NSRCT, NSReTx, or SRCT from July 2011-December 2018 at VCU Graduate Endodontic clinic were included in this study. Volumetric and linear measurements of periapical lesions on initial and recall PA and CBCT images were performed using three calibrated examiners. Changes and differences in the estimated area from PA to CBCT were …