Digital Commons Network^™

Determining Genes Involved In Recovery From Chemotherapy In 4t1, Emt6, And Eo771 Breast Cancer Cells, Akash Jagdeesh, Joseph Landry Ph.D.

UROP Posters

Breast cancer is one of the most common types of cancer, and often has poor prognosis. Traditional treatments for breast cancer include chemotherapy, which involves a chemical attack on all growing cells within the body. However, these treatments are not 100% effective, and patients might experience recurrence in their cancer months or years after achieving remission. Cancer cells can evade chemotherapy through five mechanisms: senescence, quiescence, cytoprotective autophagy, and apoptosis/necroptosis suppression. Prior studies have conducted CRISPR screens and experiments involving inhibition of epigenetic regulators, to alter the regulation of genes that can contribute to breast cancer chemotherapy resistance. This study …

Analyzing The Impact Of Positive Youth Development Programming On Youth Critical Consciousness, Jaylin Pate

UROP Posters

Youth Participatory Action Research (YPAR) is an approach to research where young people have active involvement in the research process. By uplifting youth voices and allowing the next generation to partner as co-researchers, YPAR strengthens their empowerment and agency (Anyon et. al, 2018). This study explored the impacts of YPAR programming on youth critical consciousness. Youth Voices, a community-based program, aims to support high school students in understanding positive youth development opportunities. Participants in the program attended weekly meetings and were compared to a control group with no similar intervention. Both groups completed Likert-scale surveys. Results that the intervention had …

Exploring The Knowledge Gap: Mental Health Crisis Identification Training For 911 Call Takers, Kayla L. Ralston, Emma Adcook, Gary Cuddeback, Rebecca Smith, Amy Adkins

UROP Posters

Individuals with serious mental illness (SMI) are more likely to come into contact with law enforcement and the justice system. Livingston (2016) found that 25% of people with mental illness have been arrested at least once in their lives.  Law enforcement officers often become the primary intervention in handling a mental health crisis, and most mental health-related training curricula (e.g., Crisis Intervention Team (CIT)) have focused on this group. However, the burden to initially ascertain if an emergency is mental health-related has fallen to 911 call takers and dispatchers, the first first responder. The performance outcomes outlined by the Virginia …

Establishment Of A Conditionally Replicating Guinea Pig Cytomegalovirus Model For Molecular Characterization Of Latency, Akshay R. Molakalapalli, Saketh Majeti, Michael A. Mcvoy, Jian Ben Wang

UROP Posters

Human cytomegalovirus (HCMV) is a member of the Herpesviridae that establishes life-long latent infections that pose risks of life-threatening disease upon reactivation in immunocompromised individuals. Understanding the molecular mechanisms that govern the latent state is critical for developing effective treatments. However, molecular characterization has been impeded by the scarcity of latently infected cells in vivo and the inability of current in vitro models to support the expansion of clonal latent cell lines. To address these limitations, we developed a novel cell culture model utilizing a conditionally replicating guinea pig cytomegalovirus, a relative of HCMV that mimics HCMV pathology and provides …

A Closer Look At Substance Use: Understanding Abstinence In Social Gatherings, Hillary Bogyah

UROP Posters

A Closer Look at Substance Use: Understanding Abstinence In Social Gatherings
Hillary Bogyah
Virginia Commonwealth University

Abstract

Alcohol and drug use in social settings remains a central focus in public health research, as these behaviors are often shaped by peer norms, environmental factors, and perceived social benefits. This study observes how people in various social contexts utilize drugs, alcohol, and both at the same time. A survey measuring substance usage throughout the previous month and how social interactions affected these behaviors was completed by a total of 257 participants.

The majority of respondents indicated no recent substance use. According to …

Examining Reproductive Equity In The Post-Roe United States, Yali Pang, Anna Grace Causey, Nakeina E. Douglas-Glenn, Research Institute For Social Equity Rise

Research Institute for Social Equity

Four years after the U.S. Supreme Court overturned Roe v. Wade, state-level variation in reproductive rights policy is associated with substantial geographic inequities in access to abortion and reproductive health care across the United States. The adoption of restrictive or protective reproductive rights policies is closely tied to legislative control, underscoring the political drivers of reproductive inequity. The evidence suggests that advancing reproductive equity will require coordinated national, state, and local response to strengthen healthcare infrastructure, reduce economic barriers, and establish durable legislative protections for reproductive rights.

Nurturing A Collection Development Community Within The Medical Library Association [Survey Data], Sarah Mcclung, Iris Kovar-Gough, Karen H. Gau

VCU Libraries Faculty and Staff Data

This submission is aggregated survey results comprising the supplemental material for a case study that will be published in late 2026 or early 2027, with all free-text comments removed. A version of this survey with de-identified comments included is available through the Medical Library Association Collection Development Caucus’s archives, which requires membership for access (https://www.mlanet.org/communities/caucuses).

Below is the case study abstract:

The work of health sciences collection development librarians can be isolating as they are often the sole person responsible for stewarding the collection at their institution. This case study explores the iterative process of information and experience …

“I Don’T Always See A Future For Me Here”: Oppressive Political Pressures On Lgbtq+ College Students’ Well-Being, Jodi Linley, Olivia M. Copeland, Kathleen J. Buell, Cindy Ann Kilgo, Megan Pendleton, Alex C. Lange, N F. Tennessen

Journal of Queer and Trans Studies in Education

In recent decades, colleges have broadly supported LGBTQ+ students. Now, institutions have shuttered LGBTQ+ initiatives in response to political pressures, with little consideration for the effects on students. This study answers the question, what current policy factors do LGBTQ+ college students describe as affecting their well-being, and in what ways? We analyzed 426 responses from a multi-institution study of LGBTQ+ students. By and large, students feel anxious and fearful as they navigate the current climate. Our analysis illustrated numerous factors, from the President and his administration to states and general emboldened violence, and the real and potential consequences of those …

Infrared Simulation, Sophia Zhou, Ashton Hoo, Tyler Ricks, Sebastian Fox, Kathy Phu

UROP Posters

Infrared image recognition is more difficult than visible-spectrum recognition due to limited high-quality training data. This project addresses that challenge by generating simulated infrared images using temperature-driven rendering in Unreal Engine and other 3D software. These simulations can support applications such as health monitoring, heat detection in mechanical and structural systems, thermal regulation, and engineering process control.

Evolving Trends In Organ Donation, Recovery, And Utilization In The United States: A Decade Of Change And The Impact Of Covid-19, Nirmay H. Rokad, Ohm Tripathi

UROP Posters

Evolving Trends in Organ Donation, Recovery, and Utilization in the United States: A Decade of Change and the Impact of COVID-19 Background: Over the past decade, organ donation and transplantation in the U.S. have undergone substantial changes, influenced by evolving donor practices and the COVID-19 pandemic. We examined national trends in donor types, organ recovery, utilization, and discard rates between 2012 and 2023. Methods: We analyzed SRTR/OPTN registry from 2012–2023, including total deaths, DBD (donation after brain death); DCD( donation after circulatory death); NRP (normothermic regional perfusion), organ authorization, recovery, transplantation, and discard rates. Pre-COVID (2016–2019) was compared with post-COVID …

Neuron-Enriched Extracellular Vesicle Micrornas Reflect Hormonal Suppression Associated With Oral Contraceptive Use In Young Women, Amulya Chowdhory, Rebekah Frye, Roxann Roberson-Nay

UROP Posters

Hormonal contraceptives alter hypothalamic–pituitary–ovarian (HPO) feedback, but their impact on brain-associated molecular communication remains poorly understood. Neuron- enriched extracellular vesicle (nEV) microRNAs (miRNAs), isolated from plasma, provide a minimally invasive window into brain molecular activity. This pilot study examined nEV miRNA expression in young women (ages 18–22) who were either naturally cycling or using a combined monophasic oral contraceptive (OC) pill. To identify hormonally responsive miRNAs, we calculated effect sizes (Cohen’s d) between the two groups and selected those showing large between-group differences (|d| ≥ 0.8). These miRNAs were entered into a principal component analysis (PCA) to reduce dimensionality, and …

Agrivoltaics Swot Analysis For Implementation In The United States, Vani Ramesh

UROP Posters

Agrivoltaics is the implementation of solar installations alongside agricultural land in order to improve the efficiency of land usage in both industries. Research in European and Asian countries developing agriculture and solar developments in tandem has indicated that implementation in the United States, including Virginia, is feasible and beneficial. The US has the highest energy use per capita in the world, with the increase of various technologies has resulted in land developments using higher energy levels than previously. While Virginia’s energy demand has increased with the addition of data centers. Increased energy demand and food security requirements have unearthed policy/political …

Llm-Driven Weekly Newsletter To Assess Open Source Software Project Github Health, Christian Novalski, Christopher Chavez, Ghalian Fayyadh, Kostadin Damevski

UROP Posters

Open Source Software (OSS) projects increasingly depend on a diverse set of contributors, including episodic participants who contribute intermittently. Episodic contributors represent a large portion of OSS communities, yet projects often struggle to retain them, leading to decreased project health and continuity. While dashboards and real-time communication tools support continuously active contributors, they often fail to serve the unique needs of episodic participants, who may struggle to remain informed and re-engage with project activity after periods of absence. In this study, we examine the effect of a weekly, email-based newsletter intervention designed to improve awareness and engagement among episodic OSS …

The Effects Of Coping Motives On Alcohol Use Consequences, Madisyn E. Feliciano, Samantha Pelfrey

UROP Posters

The purpose of this study was to examine the difference in alcohol use consequences between those who drink to cope with anxiety or depression symptoms and those who do not. Our research aimed to expand on earlier studies by placing emphasis on how coping with anxiety and depression influences alcohol consequences using constructs aligned with DSM-V symptom criteria. Research has consistently shown that those who drink to regulate distressing emotions experience more harmful consequences, making this an imperative area for prevention efforts. It was hypothesized that coping motivated drinking would be associated with an increased amount of alcohol related consequences. …

Bridging The Gap: Why Circulating Micrornas Have Yet To Become Clinical Biomarkers For Endometriosis, Anisha Addepalli, Mary C. Boyes

UROP Posters

Endometriosis is a chronic inflammatory disorder in which endometrial-like tissue grows  outside the uterus, leading to pelvic pain, infertility, and diagnostic delays due to the current  reliance on invasive laparoscopy. Although imaging and hormonal assays offer limited accuracy in diagnosing the disease, circulating microRNAs (miRNAs) in arterial blood have emerged as a  promising alternative method as noninvasive biomarkers because they regulate gene expression,  reflect inflammatory and angiogenic pathways, and remain stable in circulation. I propose  investigating miRNAs such as miR-17-5p, miR-451a, and the let-7 family because of their direct  involvement in the regulation of processes such as cell proliferation, immune …

Antiestrogens As Bone Protective Therapeutics For Estrogen Receptor-Positive Breast Cancer In The Presence Of Osteoporosis, Faith E. Parker, Emily K. Zboril, David C. Boyd, Rachel Myrick, J. Chuck Harrell

UROP Posters

Breast cancer (BC) is one of the most significant causes of mortality among women and the second leading cause of cancer death in women. The estrogen receptor (ER) is a key oncogenic driver in the majority of breast cancer. ER+ BC is the most common molecular subtype of BC. Management of ER+ breast cancer varies depending on menopausal status. For premenopausal women, the goal is to suppress estradiol production from the ovaries with surgical oophorectomy and/or aromatase inhibitors. In postmenopausal women, endocrine therapy (ET) serves to suppress estradiol production from sources other than the ovaries. During the menopausal transition, estradiol …

The Gendered Heart: Closing The Gender Gap In Heart Disease Diagnosis And Treatment, Aiden Varghese

UROP Posters

Cardiovascular disease (CVD) continues to be the primary cause of death for both men and women in the United States, being characterized and treated in a historically male-centric manner. This research paper will address the disparities in risk factors for heart disease between genders, gender differences in diagnosis, and gender differences in management/treatment, thereby demonstrating the critical importance of incorporating sex specific factors into the field of cardiology. It has been demonstrated that lifestyle changes such as physical activity and smoking cessation can reduce CVD risk universally. This signifies a necessary shift toward being proactive in the prevention of CVD. …

Commonwealth Times 2025-12-03

Commonwealth Times, 1969-

No abstract provided.

Unmasking Injustice In Tumultuous Times: Protest Art And Student Agency In A Summer Program, Indira Bailey

International Journal of Lifelong Learning in Art Education

In today’s political climate, academic freedom is increasingly threatened, and topics that challenge dominant narratives are often censored. Art education faces growing pressure to thoughtfully integrate these critical issues into its curriculum. This paper explores a five-day summer social justice art workshop at a Historically Black College and University (HBCU). Using a social justice art education framework, the workshop engaged undergraduate students, including non-art majors, in social justice research through creative expression and protest art making. The author argues that non-visual art students can create impactful visual counter-narratives that confront oppression while engaging deeply with both creative processes and social …

Bridging Generations Through Art: Community, Creativity, And Wellbeing, Eva V. Coker Phd, Johnson K. Wor

International Journal of Lifelong Learning in Art Education

Bridging Generations Through Art: Community, Creativity, and Wellbeing

Abstract

This article documents an intergenerational Art Day event that brought together participants of all ages to engage in a shared community art experience. Hosted in a community setting and facilitated by graduate students, the event emphasized intergenerational artmaking as a way to foster connection, creativity, mutual leaning, and wellbeing across generations. Through activities such as mindful pattern-making, montage, linoleum block printing, and weaving, participants collaborated, exchanged skills, and created artworks. Each art station was designed to support personal reflection, exploration, and participants across ages and abilities, and was informed by research …

Archaeology As Alternative Prison Education, Jayne Price Dr, Caroline Pudney Dr

Journal of Prison Education Research

This paper presents the educational focused outcomes of a set of workshops entitled 'Introduction to Archaeology’ that were delivered within a prison. The workshops were delivered as part of a project that seeks to explore the pro-social benefits and social capital (i.e. social and structural aspects that support positive identity formation) that could be developed through engagement with archaeology, specifically for those within the criminal justice system. The workshops offered a bespoke, alternative, educational offering within an adult male prison in Wales. It was designed and delivered by an archaeologist who has an established background in the field, especially in …

Commonwealth Times 2025-11-19

Commonwealth Times, 1969-

No abstract provided.

Commonwealth Times 2025-11-12

Commonwealth Times, 1969-

No abstract provided.

Do No Harm?: An Assemblage Of Care, Compliance, And Resistance To North Carolina’S Parents’ Bill Of Rights, Sarah Cornette, William Pryor Iv

Journal of Queer and Trans Studies in Education

North Carolina’s Parents’ Bill of Rights (NC-PBOR) requires school counselors to disclose sensitive student information to parents, creating profound legal-ethical dilemmas. This study examines how counselors navigate these mandates through interviews, surveys, and arts-based analysis. Findings show counselors experience institutional betrayal, ethical precarity, and emotional exhaustion, yet also engage in subtle resistance through strategic ambiguity, relational buffering, and quiet noncompliance. Methodologically, we integrate coding, poetic inquiry, and visual confection to capture affect, embodiment, and contradiction often missed by conventional analysis. By foregrounding emotion and multiplicity, we contribute to assemblage-informed policy studies and queer qualitative inquiry, while bearing witness to the …

Commonwealth Times 2025-11-05

Commonwealth Times, 1969-

No abstract provided.

Commonwealth Times 2025-10-29

Commonwealth Times, 1969-

No abstract provided.

Italian Mathematics Prison Teachers’ Perspective On The Teaching/Learning Of Mathematics In Prison School, Andrea Maffia, Luca Decembrotto, Chiara Giberti, Federica Mennuni, Gabriella Pocalana, Silvia Regola, Agnese Telloni

Journal of Prison Education Research

Teaching in the prison context is characterized by a high complexity level; it is a multifaced activity influenced by several factors depending on the specific context. We present a preliminary but overall picture of schooling in Italian prisons by considering teachers’ reflections regarding their experiences in teaching mathematics in correctional facilities. To address the gap in the current literature on this issue, we conducted a SWOT analysis on the reflection provided by a group of nine Italian mathematics teachers who teach in different prisons and with different experiences and backgrounds. Their reflection allowed us to identify and describe six theory-driven …

Commonwealth Times 2025-10-22

Commonwealth Times, 1969-

No abstract provided.

An Early Female Daguerreotypist In Spain: Marie-Agnès-Anastasie Clemandot, Madame Fritz, Maria De Los Santos García Felguera, Gregorio Escalada Sardina

Art Inquiries

Research on women who have worked in the field of photography in Spain is recent and has developed mostly in the 21st century. Still in 2025, we don’t have a book that includes them all. Outside Spain, they are completely unknown.

Here we present, as a case of study, a French woman who doesn’t fit into the rules of her time: Marie-Agnèse-Anastasie Clemandot (Le Puy-en-Velay, Haute-Loire, 1807 – Paris, 1876). She was a bookseller in Zurich, a ribbon merchant in Paris, a travelling daguerreotypist in France, Spain and Portugal and seller of leather for surgical instruments. She also had a …

Review: Luna Luna: Forgotten Fantasy, Jessica J. Stephenson

Art Inquiries

In 1987, Luna Luna, a fairground/immersive art installation, opened in Hamburg, Germany. A decades-long project in the making, it was conceived and realized by André Heller, a Vienna-based avant-garde artist, musician, film-maker, and author favoring multimedia work including circuses, parades, variety shows, firework displays and poetic gardens. Over the course of three months, about 300,000 attendees traversed Heller’s Luna Luna’s exuberant space with performances, music, and rides on art works that took the form of Ferris wheels, carousals, infinity mirror rooms, puppet shows and other theatrics. The works were created by more than 30 artists including notable 20 …