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Effect Of Ceftazidime On Systemic Cytokine Concentrations In Rats, Khalid M. Alkharfy, John A. Kellum, Reginald F. Frye, Gary R. Matzke Jan 2000

Effect Of Ceftazidime On Systemic Cytokine Concentrations In Rats, Khalid M. Alkharfy, John A. Kellum, Reginald F. Frye, Gary R. Matzke

Pharmacotherapy and Outcomes Science Publications

The effect of a single dose of ceftazidime on circulating concentrations of interleukin-6 (IL-6) and tumor necrosis factor alpha (TNF-α) in a rat model of sepsis was studied. IL-6 concentrations were significantly elevated (100 to 200 times the baseline) 6 h after ceftazidime administration in both septic and nonseptic (control) rats. TNF-α concentrations increased significantly in nonseptic (∼40 times the baseline) rats but not septic (∼2 to 3 times the baseline) rats. Ceftazidime administration was not associated with an increase in endotoxin concentrations. These findings suggest that ceftazidime modulation of proinflammatory cytokine concentrations may be independent of its antimicrobial properties.


Menorah Review (No. 48, Winter, 2000) Jan 2000

Menorah Review (No. 48, Winter, 2000)

Menorah Review

The Problem of Pain -- Science and Religion: The Case of Judaism -- Shylock the Liberal -- The Poet of Delight Beyond Suffering -- The Feminist's Corner -- American Jews: A Body Politic -- From Woodstock Shall Go Forth the Law -- Noteworthy Books


Cyanonews (Vol. 15, No. 1, July 2000), Jeff Elhai Jan 2000

Cyanonews (Vol. 15, No. 1, July 2000), Jeff Elhai

CyanoNews

CyanoNews was a newsletter that served the cyanobacteriological community from 1985 to 2003, with content provided by readers (sort of a blog before there were blogs). The newsletter reported new findings from the lab, summaries of recent meetings (often provided by graduate students and post-docs entering the field), positions sought or available, life transitions, a compendium of recent cyanobacteria-related articles, and other items of interest to those who study cyanobacteria.


Development Of A High Throughput, Molecular Diagnostic Assay For Predicting Telomerase Activity In Breast Cancer Cell Lines And Tissues, L. Elmore, A. Akalin, L. Gollahon, G. Clarke, M. Grimes, A. Ferreira-Gonzalez, C. Garrett, S. Holt Jan 2000

Development Of A High Throughput, Molecular Diagnostic Assay For Predicting Telomerase Activity In Breast Cancer Cell Lines And Tissues, L. Elmore, A. Akalin, L. Gollahon, G. Clarke, M. Grimes, A. Ferreira-Gonzalez, C. Garrett, S. Holt

Massey Comprehensive Cancer Center Publications

Telomerase is a cellular enzyme that helps to provide genomic stability in tumor cells by maintaining the integrity of telomeres. Telomerase is an RNA-dependent DNA polymerase that contains a protein component (hTERT) and an associated RNA (hTR), which is used as a template for telomere repeat addition. Telomerase activity, while not detectable in most normal human somatic cells, is associated with approximately 85% of malignant human cancers overall, including over 90% of breast cancers.

We have optimized a novel, quantitative, high-throughput telomerase activity assay using fluorescently labelled primers and Real Time quantitation via the ABI Prism 7700 (a.k.a., the TaqMan). …


The Scarab (2000-01) Jan 2000

The Scarab (2000-01)

The Scarab, 1952-2010

From the cover: "Official Organ of the Alumni Association of the Medical College of Virginia."


Millennium (2000) Jan 2000

Millennium (2000)

Millennium, 1997-2005

VCU's literary and arts magazine.


Attitudes In Physics Education: An Alternative Approach To Teaching Physics To Non-Science College Students, V. A. Niculescu, J. P. Chinnici, B. L. Brown Jan 2000

Attitudes In Physics Education: An Alternative Approach To Teaching Physics To Non-Science College Students, V. A. Niculescu, J. P. Chinnici, B. L. Brown

Journal of Mathematics and Science: Collaborative Explorations

In this article, we present an alternative way of teaching conceptual physics for non-science majors by depicting the role of physics in today's technology. The goal of this approach is to increase in the minds of non-science students the acceptance of physics as a useful component in general education, and as a major tool in comprehending the present-day technological world experienced by students outside the classroom.


[Review Of] Eric Greene. Planet Of The Apes As American Myth: Race, Politics, And Popular Culture, George H. Junne Jr Jan 2000

[Review Of] Eric Greene. Planet Of The Apes As American Myth: Race, Politics, And Popular Culture, George H. Junne Jr

Ethnic Studies Review

Planet of the Apes (1968) was such a hit movie that it spawned several sequels. They included Beneath the Planet of the Apes (1970), Escape from the Planet of the Apes (1971), Conquest of the Planet of the Apes (1972), and Battle for the Planet of the Apes (1973). In the 1974 television season CBS broadcast the series "Planet of the Apes." NBC followed with the animated Saturday morning series (September, 1975-September, 1976), "Return to the Planet of the Apes." Eric Greene clearly demonstrates that the Apes saga is little more than the support of the American myth of triumphalism: …


Kinetics And Mechanisms Of Macromolecular Disposition In The Rat Lung, Masahiro Sakagami Jan 2000

Kinetics And Mechanisms Of Macromolecular Disposition In The Rat Lung, Masahiro Sakagami

Theses and Dissertations

The kinetics and mechanisms of macromclecular absorption from the airways of the rat lung were studied in vivo and in vitro, following identical solute administration methods. The isolated perfused rat lung (IPRL) was used as an in vitro model, and the disposition of 7.4 and 4.3 kDa fluorophore-labeled polyhydroxyethylaspartamide (F-PHEA) and other small and macromolecular reference solutes was investigated across doses and in the presence of a variety of biochemical inhibitors.

Absorption profiles of F-PHEA, and the solute's lung distribution at different times after administration, were statistically identical in vivo and in vitro, showing that the IPRL possessed a viable …


Studies On The Role Creb As A Mediator Of Neurotrophin-3 Actions In Oligodendrocytes, Jamie Richard Johnson Jan 2000

Studies On The Role Creb As A Mediator Of Neurotrophin-3 Actions In Oligodendrocytes, Jamie Richard Johnson

Theses and Dissertations

In the central nervous system (CNS), oligodendrocytes (OLGs) are the cells responsible for producing the myelin membrane which allows for the saltatory conduction of neuronal impulses. We have previously shown that CREB (cAMP response element binding protein), a transcription factor that belongs to a large family bZip (basic leucine zipper) proteins, could be a mediator of neuronal signals that, coupled to different signal transduction pathways, may play different regulatory roles at specific stages of oligodendrocyte development. We have found before that, in committed OLGs, CREB activation by phosphorylation can be triggered by β-adrenergic stimulation and appears to play a role …


Examination Of Student-Active Learning Practices In A College/Middle School Educational Collaboration, S. Prattis, I. Czerwiec Jan 2000

Examination Of Student-Active Learning Practices In A College/Middle School Educational Collaboration, S. Prattis, I. Czerwiec

Journal of Mathematics and Science: Collaborative Explorations

A college and middle school student teaching collaboration was developed to interest more college students in teaching K-12 science, to enhance diversity among K-16 teaching faculties, and to inspire the K-12 students to expand their knowledge beyond their classroom curriculum. To assess our results, we used a modified Likert survey instrument and self-reflective analysis in middle school and college students, respectively. Overall, middle school students expressed satisfaction in the science learning in which they participated. In addition, college students reported that they learned specific content when made responsible for teaching material to younger students. Collaborative projects such as this one …


The Stcc Science Teaching Intern Project, N. Rapoport Jan 2000

The Stcc Science Teaching Intern Project, N. Rapoport

Journal of Mathematics and Science: Collaborative Explorations

The Springfield Technical Community College (STCC) Science Teaching Intern Project was implemented as a pilot study to give community college students an opportunity to experience science teaching. At the same time, it provided seventh graders in inner city middle schools opportunities to interact with college students and to take advantage of science resources not usually available to them. Interns attended weekly meetings and participated in an all-day science field trip at the college. Most participants also made observations in a middle school science classroom and presented a science activity in the classroom. Not only did the project provide a partnership …


Acute Gaba-A Receptor Modulation By Diazepam Following Traumatic Brain Injury In The Rat: An Immunohistochemical Study, Cynthia J. Gibson Jan 2000

Acute Gaba-A Receptor Modulation By Diazepam Following Traumatic Brain Injury In The Rat: An Immunohistochemical Study, Cynthia J. Gibson

Theses and Dissertations

Traumatic brain injury (TBI) disrupts ionic balance and produces acute widespread depolarization. Restoration of ionic balance and neuronal function after TBI may be achieved by increasing inhibitory neurotransmission (e.g., stimulating GABA-A receptors). This study used antibodies specific for β2/3 subunits to examine changes in GABA-A receptors in the rat hippocampus 24 hours following moderate fluid percussion TBI. The β2/ 3 antibody primarily stained dendritic processes. No injury related changes were found in the CA1 but extensive morphological dendritic alterations were found in the CA3 region of the hippocampus. Analysis revealed decreased length of immunoreactive processes in CA3 apical dendrites of …


Seeing Childhood In Art Education, Paul Duncum Jan 2000

Seeing Childhood In Art Education, Paul Duncum

Journal of Social Theory in Art Education

Art education theory and practice sees children as constructivist learners, but postmodern theory teaches us to see children with multiple and fragmented identities. Postmodern theory is used to examine childhood as a site of divergent discourses concerned with persistent adult attempts to control both actual children and the concept of childhood. Many alternative conceptions find pictorial form in the mass media, from abused child to nightmarish threat. This paper focuses on the idea of children as rabid consumers. It examines television advertisements aimed at children, especially by McDonald’s, Mattel and Cap Toys. Implications for the classroom as well as art …


The Journal Of Social Theory In Art Education Jan 2000

The Journal Of Social Theory In Art Education

Journal of Social Theory in Art Education

No abstract provided.


Examining Biases And Prejudices: Implications For Art Education, Shirley Hayes Yokley Jan 2000

Examining Biases And Prejudices: Implications For Art Education, Shirley Hayes Yokley

Journal of Social Theory in Art Education

In this paper, I combine an overview of Elisabeth Young-Bruehl’s (1996) socio-psychological examination of group prejudices with a critical examination of artwork by Juan Sánchez to illustrate how issues-based studies of works of art help teachers and students examine and resist biases and prejudices that contribute to oppressive or hegemonic actions.


Notes Toward A Theory Of Dialogue, Grace Deniston-Trochta, Jane Vanderbosch, Ed Check Jan 2000

Notes Toward A Theory Of Dialogue, Grace Deniston-Trochta, Jane Vanderbosch, Ed Check

Journal of Social Theory in Art Education

Multiple dimensions of dialogue as pedagogical practice are examined in the following three essays. In the first piece, “When Life Imitates Art: Notes on the Nature of Dialogue,” poet and essayist Jane Vanderbosch reflects about the politics of silence and voice in graduate school. She analyzes how power and politics charge the atmosphere of the classroom. In “The Pedagogy of Dialogue: A Relation Between Means and End,“ Grace Deniston-Trochta focuses on self-examining the possibility of dialogue in a large “pit” classroom. She proposes teacher as listener/learner, a teacher who is self-reflective and respectful. In the final essay, “Managing the Silence …


Learning On The Halfshell, M. H. Duffey, C. Roberts Jan 2000

Learning On The Halfshell, M. H. Duffey, C. Roberts

Journal of Mathematics and Science: Collaborative Explorations

No abstract provided.


Diversity Education For Pre-Service Science Teachers, D. R. Sterling Jan 2000

Diversity Education For Pre-Service Science Teachers, D. R. Sterling

Journal of Mathematics and Science: Collaborative Explorations

No abstract provided.


A General Chemistry Course For Prospective Elementary School Teachers, M. S. Lazarus Jan 2000

A General Chemistry Course For Prospective Elementary School Teachers, M. S. Lazarus

Journal of Mathematics and Science: Collaborative Explorations

The paper describes a general chemistry course designed for students who are planning to become elementary school teachers. The course has been structured so as to transmit the fun and excitement of experiencing chemistry and uncovering its basic principles by centering on laboratory and other discovery experiences. In addition, the course uses peer led workshops in which the students discuss these experiences. The course is thus a product of a particularly strong collaboration between public schools and college faculties. It is going to become a part of a new four-course sequence that will be required of all students intending to …


Active Learning In Sophomore Mathematics: A Cautionary Tale, M. Eisenberg Jan 2000

Active Learning In Sophomore Mathematics: A Cautionary Tale, M. Eisenberg

Journal of Mathematics and Science: Collaborative Explorations

Math 245: Multivariate Calculus, Linear Algebra, and Differential Equations with Computer I is the first half of a year-long sophomore sequence that emphasizes the subjects' interconnections and grounding in real-world applications. The sequence is aimed primarily at students from physical and mathematical sciences and engineering. In Fall, 1998, as a result of my affiliation with the Science, Technology, Engineering, and Mathematics Teacher Education Collaborative (STEMTEC), I continued and extended previously-introduced reforms in Math 245, including: motivating mathematical ideas with real-world phenomena; student use of computer technology; and, learning by discovery and experimentation. I also introduced additional pedagogical strategies for more …


The Effects Of Acid Deposition, B. Proffitt Jan 2000

The Effects Of Acid Deposition, B. Proffitt

Journal of Mathematics and Science: Collaborative Explorations

No abstract provided.


Bridging The Gap: The Classroom And The "Real World", P. Strickler Jan 2000

Bridging The Gap: The Classroom And The "Real World", P. Strickler

Journal of Mathematics and Science: Collaborative Explorations

No abstract provided.


[Review Of] John M. Coward. The Newspaper Indian: Native American Identity In The Press, 1820-90, Cynthia R. Kasee Jan 2000

[Review Of] John M. Coward. The Newspaper Indian: Native American Identity In The Press, 1820-90, Cynthia R. Kasee

Ethnic Studies Review

It will not come as news to people familiar with Native American history the role the print medium has played in costructing [constructing] public images of indigenous Americans. What is refreshing is the way in which Coward offers his insights on the matter. He has chosen the period of the United States' most feverish expansion into "the West," a time when newspapers and related print sources were most active in defining now-common stereotypes of both sides in the ensuing conflicts.


Educational Research Abstracts, G. Bass Jr. Jan 2000

Educational Research Abstracts, G. Bass Jr.

Journal of Mathematics and Science: Collaborative Explorations

Editors' Note: As noted in previous issues of the Journal of Mathematics and Science: Collaborative Explorations, the purpose of this Educational Research Abstract section is to present current published research on issues relevant to math and science teaching at both the K-12 and college levels. Because educational research articles are published in so many different academic journals, it is a rare public school teacher or college professor who reads all the recent published reports on a particular instructional technique or curricular advancement. Indeed, the uniqueness of various pedagogical strategies has been tacitly acknowledged by the creation of individual journals dedicated …


Journal Of Mathematics And Science: Collaborative Explorations Jan 2000

Journal Of Mathematics And Science: Collaborative Explorations

Journal of Mathematics and Science: Collaborative Explorations

No abstract provided.


Reports On A Course For Prospective High School Mathematics Teachers, D. A. Stone Jan 2000

Reports On A Course For Prospective High School Mathematics Teachers, D. A. Stone

Journal of Mathematics and Science: Collaborative Explorations

The author describes his design for a course entitled Secondary School Mathematics from an Advanced Viewpoint. He adds subjective comments on how his design has worked in practice.


A Simple Anharmonic Oscillator, K. Durlacher, J. Boyd, T. Didascalou Waterman Jan 2000

A Simple Anharmonic Oscillator, K. Durlacher, J. Boyd, T. Didascalou Waterman

Journal of Mathematics and Science: Collaborative Explorations

No abstract provided.


Integration Of Multimedia Interactive Web Tools With In-Class Active Learning, A. Ganz, K. Wongthavarawat, A. Phonphoem Jan 2000

Integration Of Multimedia Interactive Web Tools With In-Class Active Learning, A. Ganz, K. Wongthavarawat, A. Phonphoem

Journal of Mathematics and Science: Collaborative Explorations

In this paper, we present our experience with an introduction to engineering course in which we used a combination of active and collaborative teaching methods, multimedia web-based material, and web-based interactive tools. The students were engaged in active learning in class with methods such as demonstrations, hands-on work, and group work. After class, the students used the web-based material that we developed, such as multiple choice quizzes, interactive applets, and animations. We have also developed a number of web-based course management tools that were used by the course instructors. We conclude that both the students and instructors had a very …


The Thayer Method: Student Active Learning With Positive Results, E. Connors Jan 2000

The Thayer Method: Student Active Learning With Positive Results, E. Connors

Journal of Mathematics and Science: Collaborative Explorations

Graduation from West Point requires successful completion of four courses in the mathematical sciences. These core mathematics courses include topics in discrete dynamical systems, differential and integral calculus (single variable and multivariable), differential equations, linear algebra, probability, and statistics. The instructional system employed throughout the core is the "Thayer Method," named for Colonel Sylvanus Thayer, "the Father of the Military Academy." In the Thayer Method, traces of cooperative education and "discovery learning" are evident. It is quintessential active learning. The West Point catalyst is the fundamental principle that cadets are responsible for their own education.