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Commonwealth Times 2018-04-09

Commonwealth Times, 1969-

No abstract provided.

Commonwealth Times 2018-04-02

Commonwealth Times, 1969-

No abstract provided.

[2018-03-22] Meeting Of The Audit And Compliance Committee, Virginia Commonwealth University. Board Of Visitors

VCU Board of Visitors Minutes

Official minutes of the VCU Board of Visitors and its Executive Committee.

Commonwealth Times 2018-03-12

Commonwealth Times, 1969-

No abstract provided.

Commonwealth Times 2018-02-26

Commonwealth Times, 1969-

No abstract provided.

Commonwealth Times 2018-02-12

Commonwealth Times, 1969-

No abstract provided.

Review: Do The Different Sensory Areas Within The Cat Anterior Ectosylvian Sulcal Cortex Collectively Represent A Network Multisensory Hub?, M. Alex Meredith, Mark T. Wallace, H. Ruth Clemo

Anatomy and Neurobiology Publications

Current theory supports that the numerous functional areas of the cerebral cortex are organized and function as a network. Using connectional databases and computational approaches, the cerebral network has been demonstrated to exhibit a hierarchical structure composed of areas, clusters and, ultimately, hubs. Hubs are highly connected, higher-order regions that also facilitate communication between different sensory modalities. One region computationally identified network hub is the visual area of the Anterior Ectosylvian Sulcal cortex (AESc) of the cat. The Anterior Ectosylvian Visual area (AEV) is but one component of the AESc that also includes the auditory (Field of the Anterior Ectosylvian …

Theoretical Open-Loop Model Of Respiratory Mechanics In The Extremely Preterm Infant, Laura Ellwein Fix, Joseph Khoury, Russell R. Moores Jr., Lauren Linkous, Matthew Brandes, Henry J. Rozycki

Mathematics and Applied Mathematics Publications

Non-invasive ventilation is increasingly used for respiratory support in preterm infants, and is associated with a lower risk of chronic lung disease. However, this mode is often not successful in the extremely preterm infant in part due to their markedly increased chest wall compliance that does not provide enough structure against which the forces of inhalation can generate sufficient pressure. To address the continued challenge of studying treatments in this fragile population, we developed a nonlinear lumped-parameter respiratory system mechanics model of the extremely preterm infant that incorporates nonlinear lung and chest wall compliances and lung volume parameters tuned to …

Intestine‐Specific Expression Of Human Chimeric Intestinal Alkaline Phosphatase Attenuates Western Diet‐Induced Barrier Dysfunction And Glucose Intolerance, Siddhartha S. Ghosh, Hongliang He, Jing Wang, William Korzun, Paul J. Yannie, Shobha Ghosh

Internal Medicine Publications

Intestinal epithelial cell derived alkaline phosphatase (IAP) dephosphorylates/detoxifies bacterial endotoxin lipopolysaccharide (LPS) in the gut lumen. We have earlier demonstrated that consumption of high‐fat high‐cholesterol containing western type‐diet (WD) significantly reduces IAP activity, increases intestinal permeability leading to increased plasma levels of LPS and glucose intolerance. Furthermore, oral supplementation with curcumin that increased IAP activity improved intestinal barrier function as well as glucose tolerance. To directly test the hypothesis that targeted increase in IAP would protect against WD‐induced metabolic consequences, we developed intestine‐specific IAP transgenic mice where expression of human chimeric IAP is under the control of intestine‐specific villin promoter. …

Autophagy-Deficient Breast Cancer Shows Early Tumor Recurrence And Escape From Dormancy, Masoud H. Manjili

Massey Comprehensive Cancer Center Publications

Breast cancer patients who initially respond to cancer therapies often succumb to distant recurrence of the disease. It is not clear why people with the same type of breast cancer respond to treatments differently; some escape from dormancy and relapse earlier than others. In addition, some tumor clones respond to immunotherapy while others do not. We investigated how autophagy plays a role in accelerating or delaying recurrence of neu-overexpressing mouse mammary carcinoma (MMC) following adriamycin (ADR) treatment, and in affecting response to immunotherapy. We explored two strategies: 1) transient blockade of autophagy with chloroquine (CQ), which blocks fusion of autophagosomes …

Supporting Play Exploration And Early Developmental Intervention Versus Usual Care To Enhance Development Outcomes During The Transition From The Neonatal Intensive Care Unit To Home: A Pilot Randomized Controlled Trial, Stacey C. Dusing, Tanya Tripathi, Emily C. Marcinowski, Leroy R. Thacke, Lisa F. Brown, Karen D. Hendricks-Muñoz

Physical Therapy Publications

Background

While therapy services may start in the Neonatal Intensive Care Unit (NICU) there is often a gap in therapy after discharge. Supporting Play Exploration and Early Development Intervention (SPEEDI) supports parents, helping them build capacity to provide developmentally supportive opportunities starting in the NICU and continuing at home. The purpose of this single blinded randomized pilot clinical trial was to evaluate the initial efficacy of SPEEDI to improve early reaching and exploratory problem solving behaviors.

Methods

Fourteen infants born very preterm or with neonatal brain injury were randomly assigned to SPEEDI or Usual Care. The SPEEDI group participated in …

Addressing The Spiritual Needs Of People Aging With Dementia And/Or Lifelong Disabilities, Kathy Fogg Berry

Case Studies from Age in Action

Educational Objectives

1. Present the need for spiritual care as part of holistic care for people living with dementia and/or lifelong disabilities.

2. Distinguish the difference between spirituality and religion.

3. Discuss how to assess the spiritual needs of people living with dementia and/or lifelong disabilities.

4. Show through case study examples specific ways to address the spiritual needs of people living with dementia and/or lifelong disabilities.

Gerontology Theory Communicated In The Primary Grades Through Picture Books, Edward F. Ansello

Case Studies from Age in Action

Educational Objectives

1. To recognize children’s first literature as a means of socialization to aging and older people.

2. To identify children’s books that reflect basic principles of gerontology theory.

3. To help primary school teachers, grandparents, and others interested in human development use books and activities to capture children’s attention.

4. To identify a unit of six brief, overlapping modules, each with objectives, activities, and recommended readings.

Silver Saddles: An Equestrian Intervention For Older Adults With Dementia, Christine Jensen, Jessica Lyon, Tina Thomas, Rachel Scrivano

Case Studies from Age in Action

Educational Objectives

1. Demonstrate the encouraging outcomes therapeutic horseback riding programs can have for older adults with memory loss.

2. Describe the importance of trained volunteers and staff at both the riding center and the long-term care community for aiding older adults with memory loss during the therapeutic riding program.

3. Showcase the research process and pilot results.

4. Highlight lessons learned and future directions for Silver Saddles.

Prospective Longitudinal Study Of The Pregnancy Dna Methylome: The Us Pregnancy, Race, Environment, Genes (Preg) Study, Dana M. Lapato, Sara Moyer, Emily Olivares, Ananda B. Amstadter, Patricia A. Kinser, Shawn J. Latendresse, Colleen Jackson-Cook, Roxann Roberson-Nay, Jerome F. Strauss, Timothy P. York

Human and Molecular Genetics Publications

Purpose The goal of the Pregnancy, Race, Environment, Genes study was to understand how social and environmental determinants of health (SEDH), pregnancy-specific environments (PSE) and biological processes influence the timing of birth and account for the racial disparity in preterm birth. The study followed a racially diverse longitudinal cohort throughout pregnancy and included repeated measures of PSE and DNA methylation (DNAm) over the course of gestation and up to 1 year into the postpartum period.

Participants All women were between 18 and 40 years of age with singleton pregnancies and no diagnosis of diabetes or indication of assisted reproductive technology. …

Medical Literary Messenger (Vol. 5, No. 2, Spring/Summer 2018)

Medical Literary Messenger

The Essentials / Dave Morrison -- Sometimes I Pretend / Emily Pineau -- Psalm for Anorexia / Elizabeth Gauffreau -- On Harvey Dent / Bryan Walpert -- On the Level / Jane Blanchard -- Cirrhosis / Arthur Ginsberg -- Open Microphone / Stuart M. Terman -- Guest Lavatory, Beaumont Hospital, Day Five / John Jeffire -- Change of Heart / Rosie Sorenson -- Code Blue / Caroline Mosher -- Beautiful Pulses / Paul Hostovsky -- The Hospital and After / Michele Levy -- Mouth to Mouth / Charles H. Halsted -- A Meditation on Memory and Morocco / Janie Breggin …

Virginia Commonwealth University Courses [2018], Virginia Commonwealth University

VCU Bulletins

Listing of courses for the 2018-2019 year.

Virginia Commonwealth University Commencement Program [2018], Virginia Commonwealth University

VCU Commencement Programs

No abstract provided.

Temporal And Spatial Impact Of Human Cadaver Decomposition On Soil Bacterial And Arthropod Community Structure And Function, Baneshwar Singh, Kevan J. Minick, Michael S. Strickland, Kyle G. Wickings, Tawni L. Crippen, Aaron M. Tarone, M. Eric Benbow, Ness Sufrin, Jeffery K. Tomberlin, Jennifer L. Pechal

Forensic Science Publications

As vertebrate carrion decomposes, there is a release of nutrient-rich fluids into the
underlying soil, which can impact associated biological community structure and
function. How these changes alter soil biogeochemical cycles is relatively unknown and may prove useful in the identification of carrion decomposition islands that have long lasting, focal ecological effects. This study investigated the spatial (0, 1, and 5 m) and temporal (3–732 days) dynamics of human cadaver decomposition on soil bacterial and arthropod community structure and microbial function. We observed strong evidence of a predictable response to cadaver decomposition that varies over space for soil bacterial and …

Virginia Dental Journal (Vol. 95, No. 2, 2018)

Virginia Dental Journal

No abstract provided.

Search Process Checklist, Roy E. Brown

VCU Libraries Faculty and Staff Publications

The Search Process Checklist is a tool that is used in instructional sessions with nurses in reference to evidence-based practice and literature searching. It is intended as a reference handout.

It is under a creative commons license. If you would like a version that can be rebranded for your organization to use, please contact the author for an editable version.

Modular Structure In Fish Co-Occurrence Networks: A Comparison Across Spatial Scales And Grouping Methodologies, Daniel Mcgarvey Dr., Joseph Veech

Environmental Studies Publications

Network modules are used for diverse purposes, ranging from delineation of biogeographical provinces to the study of biotic interactions. We assess spatial scaling effects on modular structure, using a multi-step process to compare fish co-occurrence networks at three nested scales. We first detect modules with simulated annealing and use spatial clustering tests (interspecific distances among species’ range centroids) to determine if modules consist of species with broadly overlapping ranges; strong spatial clustering may reflect environmental filtering, while absence of spatial clustering may reflect positive interspecific relationships (commensalism or mutualism). We then use non-hierarchical, multivariate cluster analysis as an alternative method …

Crossing The Digital Divide: Monism, Dualism And The Reason Collective Action Is Critical For Cyber Theory Production, Christopher Whyte

L. Douglas Wilder School of Government and Public Affairs Publications

In studying topics in cyber conflict and cyber-security governance, scholars must ask—arguably more so than has been the case with any other emergent research agenda—where the epistemological and ontological value of different methods lies. This article describes the unique, dual methodological challenges inherent in the multifaceted program on global cyber-security and asks how problematic they are for scholarly efforts to construct knowledge about digital dynamics in world affairs. I argue that any answer to this question will vary depending on how one perceives the social science enterprise. While traditional dualistic perspectives on social science imply unique challenges for researcher, a …

Virginia Dental Journal (Vol. 95, No. 3, 2018)

Virginia Dental Journal

No abstract provided.

Triangulating Abuse Liability Assessment For Flavoured Cigar Products Using Physiological, Behavioural Economic And Subjective Assessments: A Within-Subjects Clinical Laboratory Protocol, Catherine S. Wall, Rose S. Bono, Rebecca C. Lester, Cosima Hoetger, Thokozeni Lipato, Mignonne C. Guy, Thomas E. Eissenberg, Warren K. Bickel, Andrew J. Barnes, Caroline O. Cobb

Health Policy Publications

Introduction
In the USA, Food and Drug Administration regulations prohibit the sale of flavoured cigarettes, with menthol being the exception. However, the manufacture, advertisement and sale of flavoured cigar products are permitted. Such flavourings influence positive perceptions of tobacco products and are linked to increased use. Flavourings may mask the taste of tobacco and enhance smoke inhalation, influencing toxicant exposure and abuse liability among novice tobacco users. Using clinical laboratory methods, this study investigates how flavour availability affects measures of abuse liability in young adult cigarette smokers. The specific aims are to evaluate the effect of cigar flavours on nicotine …

Abjection And Vision, Brianna Perry

AUCTUS: The Journal of Undergraduate Research and Creative Scholarship

I am currently researching medieval Christian mysticism and Black Hoodoo. Both traditions are founded upon a more involved relationship with the body and spirit. The herbalism, magic and superstition involved in the Black Hoodoo tradition have served as means of resistance among Black Americans. In light of the Tuskegee Airman incident, Black Americans’ doubt of the white medical establishment has increased. In a world dominated by reason and logic, magic makes less and less sense. The role of mystics provided new opportunities and fulfillment for medieval women, who found their voices through articulating and illustrating their visions. Visions primarily served …

Floral Symmetry Genes Elucidate The Development And Evolution Of Oil-Bee Pollinated Flowers Of Malpighiaceae And Krameriaceae, Farahnoz N. Khojayori

Theses and Dissertations

Specialization on insect and animal pollinators is thought to be the driving force for the evolution of floral traits. Specifically in the New World (NW), the oil-bee pollination syndrome has led to the convergence of floral characters in two distantly related families of core eudicots, Malpighiaceae and Krameriaceae. Both families display a flag-like structure that establishes a zygomorphic flower and floral oil rewards in epithelial elaiophores. These traits work concomitantly to attract and reward female oil-bees that help fertilize these flowers and in return receive oils. The underlying genetics of floral zygomorphy were studied in several clades of core eudicots, …

Effects Of Electronic Cigarette Liquid Solvents Propylene Glycol And Vegetable Glycerin On User Nicotine Delivery, Heart Rate, Subjective Effects, And Puff Topography, Tory Spindle

Theses and Dissertations

Electronic cigarettes (ECIGs) are a class of tobacco products that use a heating element to aerosolize a liquid, typically containing nicotine, allowing for user inhalation. Despite their rapid growth in popularity, little is known about ECIGs including how certain device and liquid factors influence nicotine delivery, user physiological and subjective responses, and puffing behavior (puff topography). Limited pre-clinical research has demonstrated that the ratio of two solvents commonly found in ECIG liquids, propylene glycol (PG) and vegetable glycerin (VG), may have an influence on the nicotine content of ECIG aerosols. However, the extent to which PG:VG ratio in ECIG liquids …

Tides, Isa N. Gagarin

Theses and Dissertations

My artistic practice creates relationships between the abstract and the personal. I define the abstract in the context of my studio work as a material exploration of color and form. The personal encompasses autobiography in relation to my sense of time and place. In this text, I use my concept of oceanic tides (considered as a temporal and spatial shift between states) to chart my activities as an artist. These activities include making objects that change in character over time, and durational work including performance and video. Interwoven throughout Tides are narrative passages based on my personal experiences, including witnessing …

Lorcaserin As A Potential Opioid-Sparing Adjunct, Kumiko M. Lippold

Theses and Dissertations

Opioids, such as oxycodone, morphine, and fentanyl, are commonly used medications in the treatment of moderate to severe pain. In spite of their efficacious analgesic properties, their increased prescribing rates by physicians and inherent abuse-related effects have led to the ongoing opioid epidemic. Their clinical utility is limited by the risk of adverse dose-dependent side effects, such as constipation and respiratory depression, and the development of tolerance and dependence. Opioid-sparing adjunctive therapies are sought to address these issues by reducing the dose of opioid needed to achieve analgesia through alternative non-opioidergic mechanisms and as a result, reduce the incidence of …