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Marginalia No. 33, Merrill-Cazier Library

Marginalia

The Digital Public Library of America and USU

In Memoriam: USU President Stanford O. Cazier

RW13: Research Week at the Library celebrating Faculty authors

The 2012 Leonard J. Arrington Writing Awards: Benjamin Harman, Peter Wosnik, Chad L. Nielsen

May Swenson's 100th Birthday Celebration, Exhibition

Founders Day 2013: the 125th Anniversary of Utah State University

Nota Bene: Merrill-Cazier Librarians' Presentations and Publications

Save the Date: Gregory A. Prince will speak at the Arrington Fall Lecture, September 19

Cover Story: Puck in Pasture, download free with LYRASIS

With Help From Our Friends: Ensuring the Library's Continuing Role

Development, Testing, And Deployment Of An Air Sampling Manifold For Spiking Elemental And Oxidized Mercury During The Reno Atmospheric Mercury Intercomparison Experiment (Ramix), B. D. Finley, D. A. Jaffe, K. Call, Seth Lyman, M. Sexauer Gustin, C. Peterson, M. Miller, T. Lyman

USU Uintah Basin Faculty Publications

The Reno Atmospheric Mercury Intercomparison Experiment (RAMIX) was in Reno, NV from August 22, 2011 to September 16, 2011. The goals of the experiment were to compare existing and new methods for measurements of ambient elemental and oxidized Hg, and to test these with quantitative spikes of Hg0, HgBr2, O3 and water vapor. In this paper we describe the design, testing, and deployment of a high flow manifold system designed to deliver ambient air and spiked compounds to multiple instruments simultaneously. The manifold was constructed of 1” OD PFA tubing and heated to 115 °C for the entire active zone. …

Fast Time Resolution Oxidized Mercury Measurements During The Reno Atmospheric Mercury Intercomparison Experiment (Ramix), Jesse L. Ambrose, Seth N. Lyman, Jiaoyan Huang, Mae Sexauer Gustin, Daneil A. Jaffe

USU Uintah Basin Faculty Publications

The Reno Atmospheric Mercury Intercomparison Experiment (RAMIX) was carried out from 22 August to 16 September, 2011 in Reno, NV to evaluate the performance of new and existing methods to measure atmospheric mercury (Hg). Measurements were made using a common sampling manifold to which controlled concentrations of Hg species, including gaseous elemental mercury (GEM) and HgBr2 (a surrogate gaseous oxidized mercury (GOM) compound), and potential interferents were added. We present an analysis of Hg measurements made using the University of Washington’s Detector for Oxidized Hg Species (DOHGS), focusing on tests of GEM and HgBr2 spike recovery, the potential for interference …

Do We Understand What The Mercury Speciation Instruments Are Actually Measuring? Results Of Ramix, Mae Sexauer Gustin, Jiaoyan Huang, Matthieu B. Miller, Christianna Peterson, Daniel A. Jaffe, Jesse Ambrose, Brandon D. Finley, Seth N. Lyman, Kevin Call, Robert Talbotl, Dara Feddersen, Huiting Mao, Steven E. Lindberg

USU Uintah Basin Faculty Publications

From August 22 to September 16, 2012, atmospheric mercury (Hg) was measured from a common manifold in the field during the Reno Atmospheric Mercury Intercomparison eXperiment. Data were collected using Tekran systems, laser induced fluorescence, and evolving new methods. The latter included the University of Washington-Detector for Oxidized Mercury, the University of Houston Mercury instrument, and a filter-based system under development by the University of Nevada-Reno. Good transmission of total Hg was found for the manifold. However, despite application of standard protocols and rigorous quality control, systematic differences in operationally defined forms of Hg were measured by the sampling systems. …

Characterization Of A Novel Fusion Protein Of Ipab And Ipad Of Shigella And Its Potential As A Pan-Shigella Vaccine, F. J. Martinez-Becerra, X. Chen, Nicholas E. Dickenson, S. P. Choudhari, K. Harrison, J. D. Clements, W. D. Picking, L. L. Van De Verg, R. I. Walker, W. L. Picking

Chemistry and Biochemistry Faculty Publications

Shigellosis is an important disease in the developing world, where about 90 million people become infected with Shigella spp. each year. We previously demonstrated that the type three secretion apparatus (T3SA) proteins IpaB and IpaD are protective antigens in the mouse lethal pulmonary model. In order to simplify vaccine formulation and process development, we have evaluated a vaccine design that incorporates both of these previously tested Shigella antigens into a single polypeptide chain. To determine if this fusion protein (DB fusion) retains the antigenic and protective capacities of IpaB and IpaD, we immunized mice with the DB fusion and compared …

Potential Role Of Wildlife In Pathogenic Contamination Of Fresh Produce, Jeff A. Langholz, Michele T. Jay-Russell

Human–Wildlife Interactions

The safety of fresh produce is an important concern in the United States, especially in the wake of recent national foodborne illness outbreaks. The agricultural industry has implemented steps to enhance food safety along the entire farm-to-fork supply chain. This includes on-farm measures to exclude wildlife and to remove its habitat in and around fields. Farmers and others from across the United States have expressed concern about the ecological consequences and uncertain food safety benefits of such practices. This article reviews the scientific rationale behind management of wildlife and its habitat as part of good agriculture practices for enhancing food …

Physiological Level Production Of Antigen-Specific Human Immunoglobulin In Cloned Transchromosomic Cattle, A. Sano, H. Matsushita, H. Wu, J. Jiao, P. Kasinathan, E. J. Sullivan, Z. Wang, Y. Kuroiwa

Animal, Dairy, and Veterinary Science Faculty Publications

Therapeutic human polyclonal antibodies (hpAbs) derived from pooled plasma from human donors are Food and Drug Administration approved biologics used in the treatment of a variety of human diseases. Powered by the natural diversity of immune response, hpAbs are effective in treating diseases caused by complex or quickly-evolving antigens such as viruses. We previously showed that transchromosomic (Tc) cattle carrying a human artificial chromosome (HAC) comprising the entire unrearranged human immunoglobulin heavy-chain (hIGH) and kappa-chain (hIGK) germline loci (named as κHAC) are capable of producing functional hpAbs when both of the bovine immunoglobulin mu heavy-chains, bIGHM and bIGHML1, are homozygously …

Synthesis And Biological Activity Of Aminoglycosides And 1,4-Naphthoquinone Derivatives, Marina Fosso Yatchang

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The research described in this dissertation is at the interface of organic chemistry and biology, and it aimed at designing and synthesizing biologically active molecules for the possible development of therapeutic agents.

Spinal muscular atrophy is an incurable disease that affects 1 in every 6000 babies, making it the leading genetic cause of infant mortality. While no treatment is available, efforts are being taken to solve this issue. Part of the work outlined in this dissertation was carried out in collaboration with researchers from the University of Missouri to investigate a potential therapeutic for this disease.

In addition, the continuous …

The Antimycobacterial Activity Of Hypericum Perforatum Herb And The Effects Of Surfactants, Shujie Shen

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Tuberculosis is a stubborn and lethal infectious disease. The world-wide tuberculosis surveillance reports that the new TB cases ranges from seven to eight million per year and deaths ranges from 1.3 to 1.6 million every year. The treatment of tuberculosis mainly depends on antituberculosis drugs, such as isoniazid, rifampin, pyrazinamide and ethambutol. However, drug-resistance acquisition is an inevitable process during tuberculosis treatment. Today, multi-drug resistant and the extensively drug-resistant TB cases have been widely reported around the world. Thus, the discovery of novel antituberculosis drugs is essential to effective TB treatment. Hypericum perforatum, also called St. John’s Wort, is …

Caehnorhabditis Elegans: A Low-Cost In Vivo Animal Model For Efficacy Studies Of Novel Antibiotics, Rylee Ann Gregory

Undergraduate Honors Capstone Projects

Since the 1940s, antibiotics have greatly reduced the adverse effects of infectious diseases caused by microbes. However, due to excessive, and often incorrect, use of known antibiotics, many organisms have adapted antibiotic resistance. Currently, over 70% of known infectious bacteria are resistant to at least one antibiotic. In the U.S. , 90,000 deaths occur each year due to infection by bacteria resistant to antibiotics. This number has increased by nearly 75,000 in the last 20 years. It is necessary, therefore, to continue developing new antibiotics in an effort to keep up with increasing antibiotic resistance. Traditional in vitro and whole …

Exitus: An Agent-Based Evacuation Simulation Model For Heterogeneous Populations, Matthew T. Manley

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Evacuation planning is important for businesses given the continuing occurrence of both natural and human-caused disasters throughout the world. Unfortunately, the traditional fire-drill approach is impractical for many large organizations but especially those responsible for airports and sports arenas. The purpose of this research was to develop a new computer program capable of simulating large scale evacuations in such buildings. The program, called Exitus, is different from other evacuation simulators in the way it considers the physical, psychological, and social characteristics of individuals with disabilities during emergency situations.

In this research, Exitus was used to simulate evacuations of three buildings …

Robust Computational Tools For Multiple Testing With Genetic Association Studies, William L. Welbourn Jr.

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

The mapping of the human genome and the completion of the Human HapMap project over the past decade have significantly altered how research is conducted with respect to the genetic epidemiology of human disease. Study designs and analytic approaches have evolved rapidly from investigations involving relatively few targeted candidate genes to hypothesis-free genome-wide association studies, where thousands – and now even millions – of single molecular mutations are simultaneously analyzed to identify regions of the genome that may influence disease. As laboratory techniques continue to improve and costs decrease, the volume of genetic data will inexorably rise, and robust tools …

A Multiple Streams Approach To Bioterrorism Policy, Craig Reeder

All Graduate Plan B and other Reports, Spring 1920 to Spring 2023

Bioterrorism is not a new phenomenon and the issues that surround bioterrorism are complex. This paper focuses on the history of bioterrorism, its current threat in public view, and then applying a theory in which explains how those problems became issues in government. The paper starts by examining a historical account of bioterrorism. The history serves a purpose to discuss the ongoing developments and struggles of drafting legislation for an ongoing problem.

After a discussion of bioterrorism from a historical perspective, the paper examines the current threat or state of bioterrorism. This will lead into a discussion about John Kingdon’s …

Genetic Diversity And Genetic Structuring At Multiple Spatial Scales Across The Range Of The Northern Leopard Frog, Rana Pipiens, Ryan P. O'Donnell

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Genetic diversity is the raw material for evolution: evolution cannot happen without genetic diversity, and the ability of a population to respond to a changing environment depends directly on how diverse its genes are. Understanding the distribution of genetic diversity is important for many reasons, including predicting whether species will be able to adapt to climate change and predicting the spread of invasive species. Information about the distribution of genetic diversity across the range of the Northern Leopard Frog, a declining species, will not only help us to ensure that the species can continue to evolve in response to changing …

A Demographic Evaluation Of Increasing Rates Of Suicide Mortality In Japan And South Korea, Sun Young Jeon

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

According to a World Health Organization report, about one million people die by suicide each year. Fortunately, rates of suicide mortality have been decreasing
among most of the OECD countries, but Japan and South Korea are the only two exceptions to this trend, which has shown increasing suicide rates over the last 25
years. A number of studies have focused on psychological motives and individual-level causes of suicide, such as depression, mental disorder, and disability. However,
as Durkheim pointed out, suicide in a society does not have any obvious relationship to the prevalence of mental disorder. With his theory indicating …

Causes And Control Of Selected Diseases Related To Backyard Chicken Flocks In Utah, David D. Frame

All Current Publications

This fact sheet will discuss the cause and control of a few chicken diseases that either may be encountered or should be prevented from occurring in small suburban/urban flocks in Utah

How To Manage Your Septic System And Protect Your Water - Homeowner Fact Sheet, Nancy Mesner

All Current Publications

Proper management of stored manure depends on proper design and construction of the storage facility, a good knowledge of the physical and chemical characteristics of the soil and subsurface geologic materials within the storage area, and proper land application of manure once it leaves the storage facility

How To Manage Stored Manure And Protect Your Water - Homeowner Fact Sheet, Nancy Mesner

All Current Publications

Runoff from improperly stored or managed manure can lead to contamination of groundwater and surface water. Land application of manure at proper agronomic rates or composting of manure conserves nutrients contained in the manure and minimizes leaching and runoff of contaminants.

Native American Uses Of Utah Forest Trees, Laurel Anderton, Darren Mcavoy, Michael R. Kuhns

All Current Publications

A number of companies in the U.S. sell free-choice or cafeteria-style mineral supplements. Their rational is that ruminants will select the minerals they need and in the quantities they require for maintenance, pregnancy and growth.

Apparent Prevalence Of Swine Brucellosis In Feral Swine In The United States, Kerri Pedersen, Sarah N. Bevins, Brandon S. Schmit, Mark W. Lutman, Michael P. Milleson, Clint T. Turnage, Troy T. Bigelow, Thomas J. Deliberto

Human–Wildlife Interactions

Samples were collected in 35 states as part of a national monitoring system to detect multiple diseases in feral swine (Sus scrofa). During March 2009 through December 2010, we collected serum samples from 4,479 feral swine from 13 states, and 159 animals tested were seropositive for brucellosis. No difference in likelihood of infection was found between males and females, but adults were more likely than sub-adults or juveniles to be exposed to brucellosis. Feral swine sampled during winter months also were more likely to be seropositive than animals sampled during other seasons. Apparent prevalence varied among states, and …

Public Perceptions Of Wildlife-Associated Disease: Risk Communication Matters, Daniel J. Decker, William F. Siemer, Darrick T. N. Evenson, Richard C. Stedman, Katherine A. Mccomas, Margaret A. Wild, Kevin T. Castle, Kirsten M. Leong

Human–Wildlife Interactions

Wildlife professionals working at the interface where conflicts arise between people and wild animals have an exceptional responsibility in the long-term interest of sustaining society’s support for wildlife and its conservation by resolving human–wildlife conflicts so that people continue to view wildlife as a valued resource. The challenge of understanding and responding to people’s concerns about wildlife is particularly acute in situations involving wildlife-associated disease and may be addressed through One Health communication. Two important questions arise in this work: (1) how will people react to the message that human health and wildlife health are linked?; and (2) will wildlife-associated …

Introduction One Health: More Than Just A Catch Phrase!, Sherman W. Jack

Human–Wildlife Interactions

No abstract provided.

Contagious Ecthyma In A Rocky Mountain Bighorn Sheep From Utah, David J. Wilson, Leslie Mcfarlane

Human–Wildlife Interactions

In December 2008, near Flaming Gorge Reservoir in northeastern Utah, a 2 ½-year-old male Rocky Mountain bighorn sheep (Ovis canadensis canadensis) was reported in poor body condition with bloody lesions covering the muzzle area. The sheep was euthanized, and samples were submitted to the Utah Veterinary Diagnostic Laboratory in Logan, Utah. The gross and microscopic lesions confirmed the diagnosis of contagious ecthyma (CE). This is the first documented report of CE in bighorn sheep from Utah.

Using Radio-Telemetry To Assess The Risk European Starlings Pose In Pathogen Transmission Among Feedlots, Shannon M. Gaukler, H. Jeffrey Homan, George M. Linz, William J. Bleier

Human–Wildlife Interactions

We monitored site-use and movements of 102 radio-tagged European starlings (Sturnus vulgaris) during the winter months at 2 concentrated animal feeding operations (feedlots) in central Kansas. Our research investigated the spatial ecology of wintering starlings as part of a broad epidemiological study on the possible role of starlings in pathogen transmission at feedlots. Site fidelity was 0.677 and 0.552 (days at capture-site per total days tagged) for feedlots A and B, respectively. Minimal exchange (9%) occurred between feedlots A and B and was often followed by a roost-site change. Starlings rarely abandoned the feedlot where they were captured, …

Brucellosis In The Greater Yellowstone Area: Disease Management At The Wildlife–Livestock Interface, Brant A. Schumaker, Dannelle E. Peck, Mandy E. Kauffman

Human–Wildlife Interactions

Elk (Cervus elaphus) and bison (Bison bison) of the Greater Yellowstone area are the last known reservoir of bovine brucellosis (Brucella abortus) in the United States. Domestic cattle occasionally contract the disease while grazing in areas where infected wild ungulates have aborted their fetuses or have given birth. Cases of brucellosis in cattle trigger costly quarantine, testing, and culling procedures. Government agencies and stakeholders, therefore, allocate valuable resources to prevent wildlife-to-cattle transmission. Scientific uncertainty about the biology, epidemiology, and economics of brucellosis makes it difficult to determine the length to which society should go to control it or the combination …

Role Of Bird Movements In The Epidemiology Of West Nile And Avian Influenza Virus, Sabir B. Muzaffar, Nichola J. Hill, John Y. Takekawa, William M. Perry, Lacy M. Smith, Walter M. Boyce

Human–Wildlife Interactions

Avian influenza virus (AIV) is influenced by site fidelity and movements of bird hosts. We examined the movement ecology of American crows (Corvus brachyrhynchos) as potential hosts for West Nile virus (WNV) and greater white-fronted geese (Anser albifrons frontalis) as potential hosts for AIVs. Research was based on radio-telemetry studies conducted in the Central Valley of California, USA. While crows were restricted to a small area of only a few square kilometers, the distribution of the geese encompassed the northern Central Valley. The crows used 1.5 to 3.5 different roosting areas monthly from February through October, …

Serologic Evidence Of Brucella And Pseudorabies In Mississippi Feral Swine, Sherman W. Jack, James C. Cumbee Jr., Kristina C. Godwin

Human–Wildlife Interactions

Feral swine (Sus scrofa) are an ever-increasing problem across the United States. Besides physical environmental damage that they cause, they may harbor and transmit a number of pathogens to humans, livestock, and other domestic animals. We sampled feral swine across the state of Mississippi for titers to several diseases. Antibodies against Brucella were found in 16 of 499 (3.2%) feral swine, and antibodies against pseudorabies (porcine herpes virus, type 1; Herpesveridae sp.) virus were identified in 37 of 499 (7.4%) feral swine from across the state of Mississippi. Evidence of classical swine fever, African swine fever, swine influenza, …

Animal-Related Injuries Resulting In Emergency Department Visits And Hospitalizations In The United States, 2006–2008, Ricky L. Langley

Human–Wildlife Interactions

This paper presents information on emergency department (ED) visits and hospitalizations resulting from an animal-caused injury from 2006 to 2008 using data collected from the Agency for Healthcare Research and Quality. Information on the number of ED visits and hospitalizations from adverse animal encounters, the types of injuries resulting from such encounters, and the therapeutic procedures performed to treat injured persons from bites or stings caused by various species of animals are presented. The economic costs of animal-caused injuries also are discussed. Over 1 million hospital ED visits and 48,000 hospitalizations were reported annually in the United States due to …

Characteristics Of Serial Title Changes And Recognition Of New Serial Works: Theoretical And Practical Implications, Mavis B. Molto

Library Faculty & Staff Publications

The paper reports findings from a study to identify characteristics of serials with title changes and then make recommendations for recognizing new works for these serials. Findings show title changes occur due to underlying subject, function, corporate, geographic, frequency, or format changes, with 80.8% of the changes being subject or function changes. It is recommended that reasons for title changes be determined from clear statements in text or elsewhere, and that new works be recognized based upon the requirements of a definition of a work. With the FRBR definition, a new work would be recognized only for a significant subject …

Molecular Interactions Of Salmonella With The Host Epithelium In Presence Of Commensals, Prerak T. Desai

All Graduate Theses and Dissertations, Spring 1920 to Summer 2023

Food-borne infections are a major source of mortality and morbidity. Salmonella causes the highest number of Food-borne bacterial infections in the US. This work contributes towards developing strategies to control Salmonella by (a) defining receptors used by Salmonella to adhere to and invade the host epithelium; (b) developing a host receptor based rapid detection method for the pathogen in food matrix; (C) and defining mechanisms of how probiotics can help alleviate Salmonella-induced cell death in the host epithelium.

We developed a cell-cell crosslinking method to discover host-microbe receptors, and discovered three new receptor-ligand interactions. Interaction of Salmonella Ef-Tu with …